LOCUS       NZ_CP116527            18533 bp    DNA     circular CON 01-MAR-2024
DEFINITION  Enterococcus faecium strain K69-1a plasmid pK69-1a-D, complete
            sequence.
ACCESSION   NZ_CP116527
VERSION     NZ_CP116527.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN23424532
            Assembly: GCF_028335465.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18533)
  AUTHORS   Biggel,M.
  TITLE     Oxazolidinone resistance genes in florfenicol resistant enterococci
            from beef cattle and veal calves at slaughter
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 18533)
  AUTHORS   Biggel,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JAN-2023) Institute for Food Safety and Hygiene,
            University of Zurich, Winterthurerstrasse 272, Zurich 8057,
            Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.5.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50x, 50x
            Sequencing Technology :: Illumina MiniSeq, Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/01/2024 02:05:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,882
            CDSs (total)                      :: 2,791
            Genes (coding)                    :: 2,696
            CDSs (with protein)               :: 2,696
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 34 of 95
            Pseudo Genes (incomplete)         :: 53 of 95
            Pseudo Genes (internal stop)      :: 25 of 95
            Pseudo Genes (multiple problems)  :: 14 of 95
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP116527.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..18533
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="K69-1a"
                     /isolation_source="fecal sample"
                     /host="Bos taurus"
                     /db_xref="taxon:1352"
                     /plasmid="pK69-1a-D"
                     /collection_date="2021"
                     /collected_by="ILS, University of Zurich"
     gene            join(17847..18533,1..267)
                     /locus_tag="PML71_RS14265"
                     /old_locus_tag="PML71_14265"
     CDS             join(17847..18533,1..267)
                     /locus_tag="PML71_RS14265"
                     /old_locus_tag="PML71_14265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_000429439.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLFE
                     KDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGSPG
                     SEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAADYII
                     AMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQKTID
                     KYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYYEQHGD
                     IEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
                     /name="ParA family protein"
     gene            239..514
                     /gene="prgO"
                     /locus_tag="PML71_RS14270"
                     /old_locus_tag="PML71_14270"
     CDS             239..514
                     /gene="prgO"
                     /locus_tag="PML71_RS14270"
                     /old_locus_tag="PML71_14270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="WP_001196543.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVDP
                     PVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
                     /name="prgO"
     gene            742..1422
                     /locus_tag="PML71_RS14275"
                     /old_locus_tag="PML71_14275"
     CDS             742..1422
                     /locus_tag="PML71_RS14275"
                     /old_locus_tag="PML71_14275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            1550..2509
                     /locus_tag="PML71_RS14280"
                     /old_locus_tag="PML71_14280"
     CDS             1550..2509
                     /locus_tag="PML71_RS14280"
                     /old_locus_tag="PML71_14280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS1252 family transposase"
                     /protein_id="WP_000222577.1"
                     /translation="MTYTHLTTDELVMIESYYHQNIKIVKIAEYLKRSRTPIYNVINFL
                     KEGHTALEYYQQYKENKKRCGRRNIVLPKKQQSYIKEKIAQGWTPDVIIGRKEKPISCS
                     VRTLYRQFKEKVFDESTLPMKGKRKPNGHQERRGKQAFKRNIVERETDYPTFKEEFGHI
                     EGDTIVGIHHKSAVITLVERLSKIIITLKPEGRKAIDIENTLNHWFGSIPRHLFKSITF
                     DCGKEFSNWKALSNQHDIAIYFADPGTPSQRALNENSNGLLRKDGLPKNMDFNQVDQAF
                     ISSVANKRNNIPRKSLDYQTPLEVFMSYMNEDILSSLI"
                     /name="IS30-like element IS1252 family transposase"
     gene            complement(2942..3514)
                     /locus_tag="PML71_RS14285"
                     /old_locus_tag="PML71_14285"
     CDS             complement(2942..3514)
                     /locus_tag="PML71_RS14285"
                     /old_locus_tag="PML71_14285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000170424.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRDR
                     PKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTSMG
                     RMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELLTSG
                     KSYKEVEAITGFSRSTLFRIKKKIEES"
                     /name="recombinase family protein"
     gene            complement(3530..4135)
                     /locus_tag="PML71_RS14290"
                     /old_locus_tag="PML71_14290"
     CDS             complement(3530..4135)
                     /locus_tag="PML71_RS14290"
                     /old_locus_tag="PML71_14290"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="WP_000599739.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTFK
                     GLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEIIKK
                     YVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDLEIR
                     YLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
                     /name="protein adenylyltransferase Fic"
     gene            complement(4333..5013)
                     /locus_tag="PML71_RS14295"
                     /old_locus_tag="PML71_14295"
     CDS             complement(4333..5013)
                     /locus_tag="PML71_RS14295"
                     /old_locus_tag="PML71_14295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            <5045..5758
                     /locus_tag="PML71_RS14300"
                     /old_locus_tag="PML71_14300"
                     /pseudo=""
     CDS             <5045..5758
                     /locus_tag="PML71_RS14300"
                     /old_locus_tag="PML71_14300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /name="C40 family peptidase"
     gene            5755..6687
                     /locus_tag="PML71_RS14305"
                     /old_locus_tag="PML71_14305"
     CDS             5755..6687
                     /locus_tag="PML71_RS14305"
                     /old_locus_tag="PML71_14305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="WP_001224318.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVLL
                     GLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSIDN
                     RMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQLITE
                     GENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSITTNEI
                     NEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTVSLTVE
                     YIDQQTKATQVSQFDLVLEKNGSNWKIIE"
                     /name="conjugal transfer protein"
     gene            6932..7048
                     /locus_tag="PML71_RS14310"
                     /old_locus_tag="PML71_14310"
     CDS             6932..7048
                     /locus_tag="PML71_RS14310"
                     /old_locus_tag="PML71_14310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="WP_001814923.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
                     /name="tetracycline resistance determinant leader peptide"
     gene            7064..8983
                     /gene="tet(M)"
                     /locus_tag="PML71_RS14315"
                     /old_locus_tag="PML71_14315"
     ARG             7065..8980
                     /name="tet(M)"
                     /gene="tet(M)"
                     /gene_name="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="98.12"
                     /coverage="100.0"
     gene            9182..10558
                     /gene="tet(L)"
                     /locus_tag="PML71_RS14320"
                     /old_locus_tag="PML71_14320"
     ARG             9183..10555
                     /name="tet(L)"
                     /gene="tet(L)"
                     /gene_name="tetracycline efflux MFS transporter Tet(L)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="95.41"
                     /coverage="100.0"
     gene            11122..12384
                     /gene="mobV"
                     /locus_tag="PML71_RS14325"
                     /old_locus_tag="PML71_14325"
     CDS             11122..12384
                     /gene="mobV"
                     /locus_tag="PML71_RS14325"
                     /old_locus_tag="PML71_14325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="WP_000119405.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENYD
                     LKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRFFE
                     ESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQDKF
                     PEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYSDKVK
                     SDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTAARDND
                     RLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERFNENVNDYNELLEENKSLKSK
                     ISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHDLEPKKNE
                     FELTHNREVKKERSRDQGMSL"
                     /name="mobV"
     gene            12629..>12967
                     /locus_tag="PML71_RS14330"
                     /old_locus_tag="PML71_14330"
                     /pseudo=""
     CDS             12629..>12967
                     /locus_tag="PML71_RS14330"
                     /old_locus_tag="PML71_14330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001611915.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(13013..13693)
                     /locus_tag="PML71_RS14335"
                     /old_locus_tag="PML71_14335"
     CDS             complement(13013..13693)
                     /locus_tag="PML71_RS14335"
                     /old_locus_tag="PML71_14335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(14126..14338)
                     /locus_tag="PML71_RS14340"
                     /old_locus_tag="PML71_14340"
     CDS             complement(14126..14338)
                     /locus_tag="PML71_RS14340"
                     /old_locus_tag="PML71_14340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002324171.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIEY
                     RTEYLELTNQTDFLLIRKQQEQEKN"
                     /name="hypothetical protein"
     gene            complement(14359..15210)
                     /locus_tag="PML71_RS14345"
                     /old_locus_tag="PML71_14345"
     CDS             complement(14359..15210)
                     /locus_tag="PML71_RS14345"
                     /old_locus_tag="PML71_14345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002287227.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILDL
                     TVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAGKL
                     FKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILFFVG
                     YVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKGIRSI
                     LKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDLELPMK
                     DK"
                     /name="hypothetical protein"
     gene            complement(15311..15607)
                     /locus_tag="PML71_RS14350"
                     /old_locus_tag="PML71_14350"
     CDS             complement(15311..15607)
                     /locus_tag="PML71_RS14350"
                     /old_locus_tag="PML71_14350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication control protein PrgN"
                     /protein_id="WP_000053907.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTRE
                     KTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
                     /name="replication control protein PrgN"
     gene            complement(15742..17235)
                     /locus_tag="PML71_RS14355"
                     /old_locus_tag="PML71_14355"
     CDS             complement(15742..17235)
                     /locus_tag="PML71_RS14355"
                     /old_locus_tag="PML71_14355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="WP_000947691.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSKQ
                     LMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINTFV
                     VDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVIDVA
                     KKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSMKLES
                     DQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTLSLAYY
                     SSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELCQQWVSP
                     TLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLNLSKKELA
                     SQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLSKEKRLDYS
                     TRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
                     /name="primase C-terminal domain-containing protein"
     ARG             9273..10558
                     /name="tet(45)"
                     /gene="tet(45)"
                     /gene_name="major facilitator superfamily (MFS) antibiotic
                     efflux pump"
                     /tool="rgi"
                     /drug_class="tetracycline antibiotic"
                     /identity="77.75"
                     /coverage="93.45"
     Typing          complement(15743..17235)
                     /name="rep_cluster_185"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          11123..12381
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="96.19"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tttaaaagca ttgttaaagg ctcggatcgg ttagaaatgt atggtgagaa tggtatccaa
       61 ttaaatgatt atgtagatcg aagatggtgg gctatttttg cagacatctt tacagaatta
      121 gaagaaagaa ttgaatacta tgaacaacat ggtgatattg aaggatttga ttatacacct
      181 aaatatgctg actcaatggc caatcatatc ctacctcttg gaaaggagat taaactaaat
      241 ggcattatta ccaacgaaca aagataagaa gaaaattggt gctgaagata tttcaattaa
      301 agatgatatt aatgtcgagt taggggaacg aaagtacact gcgaaagaaa gaaaaccagt
      361 tcaagtagat cctcccgtac taaaaaccat tcgggatctt agttatgcaa aagatattcc
      421 tatgtatgaa atagtcaaac ttgcaatgga cgcctatgtt gatactttaa acgacgagga
      481 acggattata tataatagac gatcaaaaga ttaaaatata gtaagtatac tagatatagt
      541 aaatatattt agtatactta ctatattttt agctttatta atcctaatcc ttcaaaatat
      601 gtgtattgtt tgggggtata caacattcac aaattttatt gtttctagtt tttactatac
      661 taaatatggt tctgttgcaa agttttaaat ctactatcaa ataaggtaga ataatagaaa
      721 aagatagcag gaggaatgac gatgaatcat tttaaaggaa agcaatttca gcaggatgtg
      781 attattgtag ccgtgggcta ctatcttcgt tataacctta gctatcgtga agttcaagaa
      841 atcttatatg atcgtggcat taacgtttct catacgacga tttatcgttg ggtgcaagaa
      901 tatggcaaac tactctatca aatttggaaa aagaaaaata aaaaatcctt ttattcatgg
      961 aaaatggatg aaacgtacat caaaattaaa ggaaaatggc attatttgta tcgagccatc
     1021 gatgcagatg gtttaacctt ggatatttgg ttacgtaaaa aacgggacac acaagcagcc
     1081 tatgcttttc ttaagcggtt agtgaagcag tttgatgaac cgaaggttgt agtcacagat
     1141 aaagccccct ctattacaag tgcctttaag aaactaaaag aatacggctt ttatcaaggg
     1201 acagaacatc gtaccattaa atacctgaat aatttgattg aacaagacca tcgtccagta
     1261 aagagacgca ataaattcta tcgaagttta cgcactgcct ctaccacgat taaaggcatg
     1321 gaagccattc gaggattata taagaaaacc cgaaaagaag gcactctctt cgggttttcg
     1381 gtctgtactg aaatcaaggt attattggga atcccagctt aaatcataga taccgtaagg
     1441 gattttattc tttacgccga ttgtaaaatt aagctagaca aataaataag ccattcgtgc
     1501 tacactcaaa atgtaattcc gactaaagaa aacataggag tgatcacgaa tgacctacac
     1561 ccatcttacc acggatgaac tggtgatgat agagtcttac taccaccaaa acatcaaaat
     1621 tgtgaaaatt gctgagtacc tgaaacgatc tcgaacaccg atttataacg tcattaattt
     1681 cttgaaagaa ggccatacgg ccctcgaata ctaccaacag tataaagaaa ataagaaacg
     1741 gtgtggcaga cgaaacatcg tcttgccaaa gaaacaacag tcctacatta aagaaaaaat
     1801 tgcccaaggc tggacgccag acgttatcat tgggcgtaaa gagaaaccaa tcagctgttc
     1861 cgtaagaacc ctttatcgcc agttcaagga aaaggtgttc gatgaatcga ctttgcccat
     1921 gaagggtaag cggaaaccaa atggacatca agaacgccga ggaaaacagg cttttaaacg
     1981 gaatatcgtt gaaagagaaa ctgattaccc gacatttaaa gaagagttcg gccatatcga
     2041 aggcgatacc attgtaggca ttcatcataa gagtgctgtc ataactttgg tagaacgtct
     2101 atcgaaaatc atcatcacct tgaagcccga ggggcgcaag gcgatcgata ttgagaatac
     2161 tctgaaccac tggtttggat cgattcccag acatttattt aaatccatta cctttgattg
     2221 tgggaaagaa ttctctaatt ggaaggcttt aagtaaccaa catgacatcg ctatttattt
     2281 cgctgatcca gggactcctt cgcaacgagc actgaatgaa aattccaatg gcttgctgcg
     2341 aaaagatggt ctgccaaaaa acatggattt taatcaagtc gaccaagctt ttatctcttc
     2401 agtggcgaat aagagaaaca atattccacg aaagtccttg gattatcaaa cacccctgga
     2461 agtatttatg agttacatga atgaagatat tttgtctagc ttaatttgac aaatcaaatt
     2521 atttaaaact ttgcaacaga accttagcag cagtgctgat ttttatgata gttatttggt
     2581 tcttaaatga aagatctaaa gacaatcaac accgtaggga tatggagata aaatcaatag
     2641 agtcaataga ttatttatcg ataataacac taaaaaagcc acgttcctaa acgtgactta
     2701 cgctgaacga tatgtgttgt ttggtagacg aacaaatcgt tcattataaa tatatgatgg
     2761 tatcctaata tagtaagcgt ggctagcata cctttaatta ctttaccttt tacagttacc
     2821 atacacattt tttgagcaga aatcaagtaa ataaaaaaat attatatttc acaacatgct
     2881 aatagactca tatctagaac gcattaagta tttacctgtc tggttcgctg agacttcttt
     2941 tttaactttc ttcaattttc ttctttattc taaaaagcgt actgcgactg aaaccggtta
     3001 tagcttcaac ttccttatac gatttacctg aagtaagcag ttcatatgcg tgcctcttct
     3061 tcggtgtgat tgttgctttc ggacgtcctt ctctgaaatt aggattattc tttcttgcaa
     3121 acatttttcc ttcttgggta cgttccacaa tcatatcacg ttccatttct gctacactca
     3181 acaacgtccg tgtcaccatt cgccccatgg acgtattttc aatcgttcct agattcaaaa
     3241 ccttgatcgt tacgttatca tcgagtaaag gttcaatgat ctctaatgct tctctcgtgt
     3301 tacgagcaaa tcgatcaagc ttcgtaacaa ctatttcatc tccaggcttc agaccagcca
     3361 acagctgatt gaattttggc cgatcccgtt ttgtacccgt aaatttttct gaaaaaatat
     3421 tcttcttctc tacgccgttc tcaagcaact gttgaatttg ttcttttgta ctttgagaag
     3481 cggttgagac acgtgcatat ccatatttcg tcatttggtc cacctacttt tacaaatcat
     3541 ctatcgtata ctcagaatac ccttcataga aatagctgac atcgattcct ttcatatata
     3601 actcgcgatc gtcaatttta tcagtcagag cattggaaat tagatagcgt atttccaaat
     3661 cgtttatggg acttcgctcc attgcagaaa gatagtctgc tttatcgatt aagttccaat
     3721 ctacaacttt ttgcaattct tcctttaaaa tgagatccag ccaaattcta gtacttcggc
     3781 catttccttc tcgaaatggg tgagcgatat tcatctccac atatttcttg ataatctctt
     3841 caaaagaagt ttgtggcatc tgatcaatat gctgtaacga atgttctaaa tacataactg
     3901 gtgcaaatcg aaaatttcct tttgcaatat tgaccgatcg gatttttccg gcaaaatcgt
     3961 aaatatccga aaatagaaat tcatgaattt cagataaacc tttaaatgta ccaacttcga
     4021 tttcatttat ttttccacaa tcgtacaatt ctttcgcttt ttgtttactg agtttttctt
     4081 caaccttagc caactcaact tgattggtta atcccaattt attctctaaa atcatgcgaa
     4141 atctccttaa ctttatgaca taagtttatg aaacactctc aaccccatta tatcgcgatt
     4201 ttgtttatgt gtcaaaaact attaagtttc tgacccccga tagatttttc aagtgtctct
     4261 attttgcaca gtctagttgg ttctgttgca aagttttaaa taaagaataa aatcccttac
     4321 ggtatctatg atttaagctg ggattcccaa taataccttg atttcagtac agaccgaaaa
     4381 cccgaagaga gtgccttctt ttcgggtttt cttatataat cctcgaatgg cttccatgcc
     4441 tttaatcgtg gtagaggcag tgcgtaaact tcgatagaat ttattgcgtc tctttactgg
     4501 acgatggtct tgttcaatca aattattcag gtatttaatg gtacgatgtt ctgtcccttg
     4561 ataaaagccg tattctttta gtttcttaaa ggcacttgta atagaggggg ctttatctgt
     4621 gactacaacc ttcggttcat caaactgctt cactaaccgc ttaagaaaag cataggctgc
     4681 ttgtgtgtcc cgttttttac gtaaccaaat atccaaggtt aaaccatctg catcgatggc
     4741 tcgatacaaa taatgccatt ttcctttaat tttgatgtac gtttcatcca ttttccatga
     4801 ataaaaggat tttttatttt tctttttcca aatttgatag agtagtttgc catattcttg
     4861 cacccaacga taaatcgtcg tatgagaaac gttaatgcca cgatcatata agatttcttg
     4921 aacttcacga tagctaaggt tataacgaag atagtagccc acggctacaa taatcacatc
     4981 ctgctgaaat tgctttcctt taaaatgatt catcgtcatt cctcctgcta tctttttcta
     5041 ttattctacc ttatttgata gtagatttaa aactttgcaa cagaaccgtg tgaagtattt
     5101 cagtgaatta ttagccagta gcgaaaggct cagtgtagat ttagaatcgg ttatccagtc
     5161 ctacaattat ggtggtggtt tcttagggta tgtggctaat cgtggaaata aatatacctt
     5221 tgaactggct caaagtttct caaaagagta ttcaggtggc gaaaaagtgt cttaccccaa
     5281 tcccatagcc atacctatca atgggggctg gcgatacaac tatggcaata tgttttatgt
     5341 gcaactggta acgcagtatc ttgtcacaac agagtttgat gatgatacgg tacaagccat
     5401 catggacgaa gcactgaaat atgagggctg gcgatacgtt tacggtggag cttccccgac
     5461 tacttctttt gattgtagcg gactgacaca atggacgtat ggaaaagctg gaattaactt
     5521 accacgaacc gcacaacagc aatatgatgt gacccagcat atcccactat cggaagcaca
     5581 agctggcgat ttggttttct ttcattctac ctataacgct ggctcttata ttactcatgt
     5641 tgggatatac cttggcaata accgtatgtt tcatgcaggc gacccaatcg gttatgccga
     5701 cttaacaagc ccctactggc aacagcattt agtgggagca ggacgaatca aacaatgaga
     5761 aaggaagatt taatgatgaa atttagaaaa aatcagaata aagaaaaaca gataccaaag
     5821 gaaaagaaac ctcgtgtcta taaggtcaat cctcataaaa aggttgtgat tgccttgtgg
     5881 gtacttttag ggcttagttt cagctttgcg atattcaagc actttacagc tatagatact
     5941 catactattc acgaaacaac tatcatagaa aaggaatacg ttgatactca tcatgtagaa
     6001 aattttgtag agaactttgc gaaagtctac tattcatggg agcaatccga taagtccatt
     6061 gataatcgaa tggaaagtct aaaaggctat ctgacagatg aacttcaagc tctcaatgtt
     6121 gatacagtac gcaaagatat tcctgtatcg tcttctgtaa gaggatttca gatatggacg
     6181 gtagagccaa ctggcgacaa tgagtttaat gtaacctaca gtgtagacca gctcattaca
     6241 gagggagaaa atacaaagac cgtccactct gcttatatag tgagtgtcta tgtagatggt
     6301 tctggaaata tggtactggt taagaatccg accattacca acatacctaa gaaatcaagt
     6361 tataaaccaa aagccattga aagtgagggg acggttgatt ccattacaac caatgaaatc
     6421 aatgagtttt taacgacgtt cttcaagctc tatcctacag cgacagccag tgaactttcc
     6481 tactatgtga atgacgggat attaaaacca atcggaaaag agtacatctt tcaagaactg
     6541 gtaaatccta ttcacaatcg taaggataat caagtcacgg tatcgctgac agtggagtat
     6601 atcgaccagc agaccaaagc aacgcaggta tctcaatttg atttggtact tgaaaagaac
     6661 gggagtaatt ggaagattat agaataacaa atattggtac attattacag ctattttgta
     6721 atcacgtact ctctttgata aaaaattgga gattccttta caaatatgct cttacgtgct
     6781 attatttaag tatctattta aaaggagtta ataaatatgc ggcaaggtat tcttaaataa
     6841 actgtcaatt tgatagtggg aacaaataat tggatgtcct tttttaggag ggcttagttt
     6901 tttgtaccca gtttaagaat acctttatca tgtgattcta aagtatccgg agaatatctg
     6961 tatgctttgt atgcctatgg ttatgcataa aaatcccagt gataagagta tttatcactg
     7021 ggatttttat gcccttttgg gcttttgaat ggaggaaaat cacatgaaaa ttattaatat
     7081 tggagtttta gctcatgttg atgcgggaaa aactacctta acagaaagct tattatataa
     7141 cagtggagcg attacagaat taggaagcgt ggacaaaggt acaacgagga cggataatac
     7201 gcttttagaa cgtcagagag gaattacaat tcagacagga ataacctctt ttcagtggga
     7261 aaatacgaag gtgaacatca tagacacgcc aggacatatg gatttcttag cagaagtata
     7321 tcgttcatta tcagttttag atggggcaat tctactgatt tctgcaaaag atggcgtaca
     7381 agcacaaact cgtatattat ttcatgcact taggaaaatg gggattccca caatcttttt
     7441 tatcaataag attgaccaaa atggaattga tttatcaacg gtttatcagg atattaaaga
     7501 gaaactttct gccgaaattg taatcaaaca gaaggtagaa ctgtatccta atatgtgtgt
     7561 gacgaacttt accgaatctg aacaatggga tacggtaata gagggaaacg atgacctttt
     7621 agagaaatat atgtccggta aatcattaga agcattggaa ctcgaacaag aggaaagcat
     7681 aagatttcag aattgttccc tgttccctgt ttatcacgga agtgcaaaaa acaatatagg
     7741 gattgataac cttatagaag tgattacgaa taaattttat tcatcaacac atcgaggtca
     7801 gtctgaactt tgcggaaatg ttttcaaaat tgaatataca aaaaaaagac aacgtcttgc
     7861 atatatacgt ctttatagtg gcgtactgca tttgcgagat tcggttagaa tatcggaaaa
     7921 ggaaaaaata aaaattacag aaatgtatac ttcaataaat ggtgaattat gtaaaatcga
     7981 taaggcttat tccggggaaa ttgttatttt gcagaatgag tttttgaagt taaatagtgt
     8041 tcttggagat acaaagctat tgccacagag agagagaatt gaaaatcccc tccctctgct
     8101 gcaaacaact gttgaaccga gcaaacctca acaaagggaa atgttacttg atgcactttt
     8161 agaaatctcc gacagtgacc cgcttctaca atattatgtg gattctacga cacatgaaat
     8221 tatactttct ttcttaggga aagtacaaat ggaagtgact tgtgctctat tgcaagaaaa
     8281 gtatcatgtg gaggtaaaaa taaaaaagcc tacagtcatt tatatggaaa gaccgttaaa
     8341 aaaagcagag tataccattc acatcgaagt gccaccgaat cccttctggg cttccattgg
     8401 tttatctgta tcaccgcttc cgttgggaag tggaatgcag tatgagagct cggtttctct
     8461 tggatactta aatcaatcat ttcaaaatgc agttatggaa gggatacgct atggttgcga
     8521 acaaggatta tatggttgga atgtgacgga ttgtaaaatc tgttttaagt atggcttata
     8581 ctatagccct gttagtaccc cagcagattt tcggatgctt gctcctattg tattggaaca
     8641 agttttaaaa aaagctggaa cagaattgtt agagccatat cttagtttta aaatttatgc
     8701 accacaagaa tatctttcac gagcatatga cgatgctcct aaatattgtg cgaacatcgt
     8761 agacactcaa ctgaaaaata atgaggtcat tcttagtgga gaaattcctg ctcggtgtat
     8821 tcaagaatat cgtaatgatt taactttctt tacaaatgga cgtagcgttt gtttaacaga
     8881 gttaaaagga tatcaggtta ccactggcga acctgtttgc cagccccgtc gtccaaatag
     8941 tcggatagat aaagtacgat atatgttcaa taaaataact tagcacattt tatattgtta
     9001 tataaatgtg gcttcttgtt aaacgaaacg agatgaaata ttttttaata aagatttgaa
     9061 ttaaagtgta aaggaggaat taattatgaa gtaaaatgaa tgtaacaggg ttcaattaaa
     9121 agagggaagc gtatcattaa ccctataaac tacgtctgcc ctcattattg gagggtgaaa
     9181 tgtgaataca tcctattcac aatcgaattt acgacacaac caaattttaa tttggctttg
     9241 cattttatct ttttttagcg tattaaatga aatggttttg aacgtctcat tacctgatat
     9301 tgcaaatgat tttaataaac caccggcgag tacaaactgg gtgaacacag cctttatgtt
     9361 aaccttttct attggaacag ctctatatgg aaagctatct gatcagctag gcattaaaag
     9421 gttactccta tttgggatta taataaattg cttcggatcg gtaattgggt ttgttggaca
     9481 ttctttcttt cccatactta ttctggctcg atttattcaa ggagctggtg cagctgcatt
     9541 tccagcactc gtgatggttg tagttgcgcg ctatattcca aaggaaaata ggggtaaagc
     9601 atttggtctt attggatcga tagtagccat gggagaagga gtcggtccag cgattggtgg
     9661 aatgatagcc cattatattc attggtccta tcttctactc attcctatga taacaattat
     9721 cactgttccg tttcttatga aattattaaa gaaagaagta aggataaaag gtcattttga
     9781 tatcaaagga attatactaa tgtctgtagg cattgtattt tttatgttgt ttacaacatc
     9841 atatagcatt tcttttctta tcgttagcgt gctgtcattc ctgatatttg taaaacatat
     9901 caggaaagta acagatcctt ttgttgatcc cggattaggg aaaaatatac cttttatgat
     9961 tggagttctt tgtgggggaa ttatatttgg aacagtagca gggtttgtct ctatggttcc
    10021 ttatatgatg aaagatgttc accagctaag tactgccgaa atcggaagtg taattatttt
    10081 ccctggaaca atgagtgtca ttattttcgg ctacattggt gggatacttg ttgatagaag
    10141 aggtccttta tacgtgttaa acatcggagt tacatttctt tctgttagct ttttaactgc
    10201 tgcctttttt ttagaagtaa caccatggtt actgacaatt atattagttt ttgtttttgg
    10261 tgggctgtca ttcaccaaaa cagttatatc tacaattgtt tcaagtagtt tgaaacaaaa
    10321 ggaagctggt gccggaatga gtttgcttaa ttttaccagc tttttatcag agggaacagg
    10381 tattgcaatt gttggtggtt tattatctgt acgcttgctg aatcagaagt tgctacctat
    10441 ggaccttgat caatccactt acttgtatag taatatgcta ttcctttttt caggaatcat
    10501 tgtcattagt tggctggtta ccttgaatgt atataaacat tctcaaaggg atttctaaat
    10561 cgttaaggga tcaactttgg gagagagttc aaaattgatc ctttttttat aacaggaatt
    10621 caaatctttt tgttccatta aagggcgcga ttgctgaata aaagatacga gagacctctc
    10681 ttgtatcttt tttattttga gtggttttgt ccgttacact agaaaaccga aagacaataa
    10741 aaattttatt cttgctgagt ctggctttcg gtaagctaga caaaacggac aaaataaaaa
    10801 ttggcaaggg tttaaaggtg gagatttttt gagtgatctt ctcaaaaaat actacctgtc
    10861 ccttgctgat ttttaaacga gcacgagagc aaaacccccc tttgctgagg tggcagaggg
    10921 caggtttttt tgtttctttt ttctcgtaaa aaaaagaaag gtcttaaagg ttttatggtt
    10981 ttggtcggca ctgccgacag cctcgcagag cacacacttt atgaatataa agtatagtgt
    11041 gttatacttt acttggaagt ggttgccgga aagagcgaaa atgcctcaca tttgtgccac
    11101 ctaaaaagga gcgatttaca tatgagttat gcagtttgta gaatgcaaaa agtgaaatca
    11161 gctggactaa aaggcatgca atttcataat caaagagagc gaaaaagtag aacgaatgat
    11221 gatattgacc atgagcgaac acgtgaaaat tatgatttga aaaatgataa aaatattgat
    11281 tacaacgaac gtgtcaaaga aattattgaa tcacaaaaaa caggtacaag aaaaacgagg
    11341 aaagatgctg ttcttgtaaa tgagttgcta gtaacatctg accgagattt ttttgagcaa
    11401 ctggatccag gagaacaaaa acgatttttt gaggaaagtt ataaattatt ttccgaacga
    11461 tatggcaagc aaaatattgc ttatgcaaca gttcataatg atgagcaaac ccctcacatg
    11521 catttaggtg ttgtgcctat gcgtgatgga aaactgcaag gaaaaaatgt gtttaatcgt
    11581 caagaactgt tatggctaca agataaattc cccgagcata tgaaaaaaca gggttttgag
    11641 ttgaagcgtg gtgaacgtgg ctctgaccgt aaacatattg agacagctaa atttaaaaaa
    11701 caaactttgg aaaaagagat tgattttcta gaaaaaaatt tagcagttaa aaaagatgaa
    11761 tggactgctt atagcgataa agttaaatca gatttagaag taccagcgaa acgacacatg
    11821 aaaagtgttg aagtgccaac gggtgaaaag tccatgtttg gtttgggaaa agaaataatg
    11881 aaaacagaaa agaaaccaac caaaaatgtt gttatatcgg agcgtgatta taaaaactta
    11941 gtgactgctg cgagagataa cgataggtta aaacagcatg ttagaaatct catgagtact
    12001 gatatggcga gagaatataa aaaattaagt aaagaacatg ggcaagttaa agaaaaatat
    12061 agtggtcttg tagagcgatt taatgaaaat gtaaatgatt ataatgagtt gcttgaagaa
    12121 aacaagtctt taaagtctaa aataagcgat ttaaagcgtg atgtgagttt aatctatgaa
    12181 agcactaagg aattccttaa ggaacgtaca gacggcttaa aagcctttaa aaacgttttt
    12241 aaggggtttg tagacaaggt aaaggataaa acagcacaat tccaagaaaa acacgattta
    12301 gaacctaaaa agaacgaatt tgaactaact cataaccgag aggtaaaaaa agaacgaagt
    12361 cgagatcagg gaatgagttt ataaaataaa aaaagcacct gaaaaggtgt ctttttttga
    12421 tggttttgaa cttgttcttt cttatcttga tacatataga aataacgtca tttttatttt
    12481 agttgctgaa aggtgcgttg aagtgttggt atgtatgtgt tttaaagtat tgaaaaccct
    12541 taaaattggt tgcacagaaa aaccccatct gttaaagtta taagtgacca aacaaataac
    12601 taaatagatg ggggtttctt ttaatattat gtgtcctaat agtagcattt attcagatga
    12661 aaaatcaagg gttttagtgg acaagacaaa aagtggaaaa gtgagaccat ggagagaaaa
    12721 gaaaatcgct aatgttgatt actttgaact tctgcatatt cttgaattta aaaaggctga
    12781 aagagtaaaa gattgtgctg aaatattaga gtataaacaa aatcgtgaaa caggcgaaag
    12841 aaagttgtat cgagtgtggt tttgtaaatc caggctttgt ccaatgtgca actggaggag
    12901 agcaatgaaa catggcattc agtcacaaaa ggttgttgct gaagttatta aacaaaaggg
    12961 ttctgttgca aagttttaaa taaagaataa aatcccttac ggtatctatg atttaagctg
    13021 ggattcccaa taataccttg atttcagtac agaccgaaaa cccgaagaga gtgccttctt
    13081 ttcgggtttt cttatataat cctcgaatgg cttccatgcc tttaatcgtg gtagaggcag
    13141 tgcgtaaact tcgatagaat ttattgcgtc tctttactgg acgatggtct tgttcaatca
    13201 aattattcag gtatttaatg gtacgatgtt ctgtcccttg ataaaagccg tattctttta
    13261 gtttcttaaa ggcacttgta atagaggggg ctttatctgt gactacaacc ttcggttcat
    13321 caaactgctt cactaaccgc ttaagaaaag cataggctgc ttgtgtgtcc cgttttttac
    13381 gtaaccaaat atccaaggtt aaaccatctg catcgatggc tcgatacaaa taatgccatt
    13441 ttcctttaat tttgatgtac gtttcatcca ttttccatga ataaaaggat tttttatttt
    13501 tctttttcca aatttgatag agtagtttgc catattcttg cacccaacga taaatcgtcg
    13561 tatgagaaac gttaatgcca cgatcatata agatttcttg aacttcacga tagctaaggt
    13621 tataacgaag atagtagccc acggctacaa taatcacatc ctgctgaaat tgctttcctt
    13681 taaaatgatt catcgtcatt cctcctgcta tctttttcta ttattctacc ttatttgata
    13741 gtagatttaa aactttgcaa cagaaccgtt cgtcacatct tcgatcaatt tctcttacga
    13801 ttttctcatc cacatttctt attcttactt ccatattaat tcctccaatt taaaaaggat
    13861 agcgaaaagg agcctatcct ttttgctatc ctactaccct ccttttacta tccttcacta
    13921 tcctttcact atcctatttt taaatatttt gttcccacat ttatttttga gaaacgtaat
    13981 aggcacagcc tattggaaca ctttttttaa aaagtgttcc cacgtttcct tatgctcttt
    14041 acaaataaag gcttttagag acgttctgga attttagatt ccttgaattg ttcccattca
    14101 tcaatcaatt ggctataagt agccattaat ttttttcttg ctcttgttgc tttcgaatca
    14161 acaaaaaatc agtttgattc gttaattcta aatattctgt tcggtattca atgttcatcg
    14221 tacccgtttt actacatagt aactgattat gacgttcttt cactttgaat aactgctcct
    14281 tctttaaggt ttttaactcc atgccaacta taagcacaat cctgtataga ggaatcattt
    14341 tcaaacgatt ctccataatt atttatcttt cattggaagt tctaaatcac tactgttcca
    14401 aaaaatgtat ggtttgtttt gacgaatatt acttccatct aaccacaatt ttccgatgcc
    14461 atatcgtagg cttgcttcga cttcataaaa attgtagatc tcttttcttc gatctattgc
    14521 tttcatttcc tggccatttt ttaaaataga tctgatgccc ttaacagtag attcatggat
    14581 actcgtgtga acgatatccg tattgatcaa ttcgtcatat cttccaaaat caacattgta
    14641 ctcataacca agaagtgtcg gaatcaggtc aatttcaatt tctttttcaa ttgaacgttt
    14701 aataagtttc gtggatacat acccgacaaa aaagagaata atacccactt caaacaaata
    14761 catgtgtcca tttacaaagt gaataaacgt caataaaaaa tccttcactc cttttgttgt
    14821 tcttccagat tgttcaattt gttttattaa agtcgctaga attgcattta caacaattaa
    14881 atcgaatagg cttttgaaaa gttttcctgc tgttaatttt tgcctggtaa attgcatgac
    14941 taattgagta aaaatagaca atagcatgac aaaaatcaac gtcattagca ctgtaaaaat
    15001 gtctgatgct gcaatcctat tgggatcatt tatcaagtaa taagccgttc caaatactcc
    15061 aatcgagtaa acggttaaat caagaataag tcgtgccccg taactacaaa gttttcctaa
    15121 tggccataat tgcaataccc aaaatttctt tcgtttgcta tttcttttca gaggaagcca
    15181 ggtgtgttca atccagtcgt ccgatttcat ttcgatttct tccctaaatt ctttccttta
    15241 acgttttcct ttgctacttt agcagcgata ggttgctcaa tgaaccaatt ttttaagtaa
    15301 ataaaaacta ctactggata tacttcttcc tttttcttaa ctcgttagct attttatact
    15361 caatatactc ctgctctaac acacacaaac aatcatatac ctgatccata gtctccccag
    15421 aagctaagga caacccatga agaaactcaa tcggcaaaga agcaactgtt ttttccctgg
    15481 taacccaaga agacaaagtc ccctgcttaa aaccataaag ctcacagaac acttccacag
    15541 ataatcccaa acgaccaatg ataaacacat taacaggatg tgaatagaca taatttttta
    15601 acgacataca acttcctcca tgatacataa gactgcatac gcagttataa gtataccacc
    15661 tacacgtagc taggcaaagg gagcaacacc tacagaagta tcatagatat attgtatagg
    15721 gcaatttgca ccttttattt ttcaacctgt atctacttca aaaagattca cttctttaag
    15781 agggttcaag ggggttgata attgtctaaa tgtctcttct actaagctct cgttgagtcc
    15841 aaatacctct gtgatccttg ttgaataatc tagtctcttt tctttactta gttgaataac
    15901 cctcgcgaac aacgttttga ctgaagcaat gatcattccg ccatttcttc ctcgtgttac
    15961 cttgtagaag actttattct cctctcgtaa ctcatttaag atcttatcaa gtgttcgctt
    16021 gggcatcgtt agttgtgaag ccaattcttt ttttgacagg ttcaaataag gctcactagc
    16081 aagacttttt tcgcttagat aagccaatag atcttctttc cattcatttt tatgactata
    16141 ttttctttga tctcgtggct ttttaaattt ccaccagcca cgtcgttgaa tgaacagatc
    16201 attatttttt aaggttggtg aaacccattg ctggcacaat tcaataatga attctctgct
    16261 tgctgcttga taattaccag aataagcact acgtacaatc tttactaatt ctgcttcaga
    16321 tagcggttcc tgtaaccgtt cgttgaatgt gaacatattg tattcgcaag tatccaatgc
    16381 ataacctgaa gagtaataag ctaaagaaag cgtgaaaatc acattatttc gaccaagacg
    16441 tccttctccg ccgacgatgt ttgctttatg aagtaacata tcgaaccacg gttcatctac
    16501 ttgacgaatt tcttttttct caggaaagac aattagtttt cgttctcgat cttcttttgt
    16561 tttttgatct gattcaagct tcatcgacca ttgaatccag tcagcaaaag aatactgata
    16621 gttcatttct ttaaaaacaa tattattttc ttgtgggaat cgagcaattc cgaagtggtt
    16681 acatcctaga tccactccgg acaatttttc agccaactgt agacgaattg tttttgaaat
    16741 tttttttgct acatcgatca ccttgaaatt gcttttcttt gtgacatagc ctggtgtctt
    16801 tagtacaaaa taaacttgat aaccatgatc tgattctaaa attagcgttg gcatgtagcc
    16861 cacttgatct aaacaggcta aaataatttc gccttgatgg ttctcttttg aatcgatatc
    16921 aactacaaat gtgttgattt gacttaagtt tttctcagaa tgacctttaa ccactgttcg
    16981 ataatcatcc gcataagtac caaagcgata ggtattaggt gtccaatgcg ttagtttctt
    17041 ttcgttctct aaaatagctt cttccgaagt aatgaccata ccacgcccaa cattcattaa
    17101 ttgcttgcta cggtacgcaa agatagcacc actcctactg gaatcaatat gacctgcagg
    17161 tttcatggtg ctgtttcgat atttgtatgt acgtaagccg tttttaagaa tagctgaata
    17221 aatttcgctc aacatcgatt gtaacgtcct ttctcaaaca aaaagagaac acagtttagc
    17281 tttaatctca gccatagtat gtgttctctc ttcagtgttt aagaatattt aatttaagta
    17341 cactaaataa actttcttct gttgagttgc tcgccttttt ttggtagaat aaaggcaatc
    17401 ggaaaaggta tccgatcaac ttttaatata agtagttggt agctacttac atattcttga
    17461 gacgagcgtg aacacatgtc ctaaccatgt gattcagaaa taattgattc tgctaaaatc
    17521 aattatttcc gtctcttttt tttatgtaat ttttctgttt aaagagtacc actgcttttg
    17581 ctactttgta aatagtgaat tatctgtggt ttctatagaa ttaagtttac ctcttttcac
    17641 tctaaattgt caacgcaaaa cgcacaaata tattttgaca ttttgaatat atctgatata
    17701 ctgaatatag caaatatatt tagtatatcc actatattcc ttataaagtc tgaattctta
    17761 tcaatttgga gtatattaga tatatcgaat atattaagta tatgaagtat actaaatata
    17821 tttagtatag gaaattggag ggaactatgg aaaacttacg gactgcattt aaaacatcag
    17881 ataaactagg aaaagttgta atgcttacag gtagaaaagg cggcattggt aagactacag
    17941 acaatgattt attagcgatt gtttctagtc aactttttga aaaagacgtg ttgctaattg
    18001 attatgacca acaaagaaat actacttcca acattggatc aacgtatcaa attactagct
    18061 ttgatcgatc catgtctgca gcaatcaaaa aaggggactg ggtttcaggt attactcaag
    18121 taagtccaca tttatatatt atggctggct ctcctggatc tgaagaactt aatgaatact
    18181 tgtccgaaaa atatcctgat cgtcgtaaga gatcattggc cttcattaaa cctttagaag
    18241 aattgagaaa aaatttcgat tatatcttta tcgactgccc accatcaaca gataatgtgg
    18301 ttcgtgcatt cttaactgct gcagattata ttattgcaat gcaagaatta aaacggtacg
    18361 caatggaagg aacagaagat tttattaata aagttttagt tccgattgtc acgaattttg
    18421 aagagtctca tcttcaaatc attggaattt tgcctgttct tttctcagtg cgacgttcct
    18481 ctcaacacgc aaactatcaa aaaacaattg ataagtatgg tgaatcaaac att
//
