LOCUS       NZ_CP116184            13744 bp    DNA     circular CON 25-FEB-2024
DEFINITION  Escherichia coli strain DETEC-E480 plasmid pDETEC57, complete
            sequence.
ACCESSION   NZ_CP116184
VERSION     NZ_CP116184.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN31988416
            Assembly: GCF_027944955.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13744)
  AUTHORS   Moran,R.A., Baomo,L., Doughty,E.L., Guo,Y., Ba,X., van Schaik,W.,
            Zhuo,C. and McNally,A.
  TITLE     Extended-spectrum beta-lactamase genes traverse the Escherichia coli
            populations of ICU patients, staff and environment
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 13744)
  AUTHORS   Moran,R.A., Baomo,L., Doughty,E.L., Guo,Y., Ba,X., van Schaik,W.,
            Zhuo,C. and McNally,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JAN-2023) Institute of Microbiology and Infection,
            University of Birmingham, Institute of Microbiology and Infection,
            Birmingham B15 2TT, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 10x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/25/2024 01:54:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,153
            CDSs (total)                      :: 5,044
            Genes (coding)                    :: 4,810
            CDSs (with protein)               :: 4,810
            Genes (RNA)                       :: 109
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 234
            CDSs (without protein)            :: 234
            Pseudo Genes (ambiguous residues) :: 0 of 234
            Pseudo Genes (frameshifted)       :: 77 of 234
            Pseudo Genes (incomplete)         :: 176 of 234
            Pseudo Genes (internal stop)      :: 34 of 234
            Pseudo Genes (multiple problems)  :: 47 of 234
            Pseudo Genes (short protein)      :: 3 of 234
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP116184.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..13744
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="DETEC-E480"
                     /isolation_source="button"
                     /db_xref="taxon:562"
                     /plasmid="pDETEC57"
                     /geo_loc_name="China: Guangzhou"
                     /collection_date="2019-08-19"
     gene            137..562
                     /locus_tag="PIB86_RS25605"
                     /old_locus_tag="PIB86_25605"
     CDS             137..562
                     /locus_tag="PIB86_RS25605"
                     /old_locus_tag="PIB86_25605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001373091.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_000422741.1"
                     /translation="MELQDWRKEPRKNYSNEFKLRMVELASQPGACVAQIARENGVNDN
                     VIFKWLRLWQNEGRVSRRLPVTTSSDTGVELLPVEITPDEQKEPVAAIAPSLSTSTQTR
                     VSASSCKVEFRHGNMTLENPSPELLTVLIRELTGRGR"
                     /name="transposase"
     gene            559..909
                     /gene="tnpB"
                     /locus_tag="PIB86_RS25610"
                     /old_locus_tag="PIB86_25610"
     CDS             559..909
                     /gene="tnpB"
                     /locus_tag="PIB86_RS25610"
                     /old_locus_tag="PIB86_25610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311895.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="WP_000624722.1"
                     /translation="MISLPSGTRIWLVAGVTDMRKSFNGLGEQVQHVLNDNPFSGHLFI
                     FRGRRGDTVKILWADADGLCLFTKRLEEGQFIWPAVRDGKVSITRSQLAMLLDKLDWRQ
                     PKTSSRNSLTML"
                     /name="tnpB"
     gene            940..2553
                     /locus_tag="PIB86_RS25615"
                     /old_locus_tag="PIB86_25615"
     CDS             940..2553
                     /locus_tag="PIB86_RS25615"
                     /old_locus_tag="PIB86_25615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080195.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66-like element ISEc23 family transposase"
                     /protein_id="WP_000080195.1"
                     /translation="MSQKYLIRIAELERLLSEQAEALRQKDQQLSLVEETEAFLRSALT
                     RAEEKIEEDEREIEHLRAQIEKLRRMLFGTRSEKLRREVELAEALLKQREQDSDRYSGR
                     EDDPQVPRQLRQSRHRRPLPAHLPREIHRLEPEESCCPECGGELDYLGEVSAEQLELVS
                     SALKVIRTERVKKACTKCDCIVEAPAPSRPIERGIAGPGLLARVLTGKYCEHLPLYRQS
                     EIFARQGVELSRALLSNWVDACCQLMTPVNDALYRYVMNTRKVHTDDTPVKVLAPGQKK
                     AKTGRIWTYVRDDRNVGSSSPPAVWFAYSPNRQGKHPEQHLRPFRGILQADAFTGYDRL
                     FSAEREGGALTEVACWAHARRKIHDVYISSKSATAEEALKRISELYAIEDEIRGLPESE
                     RLAVRQQRSKVLLTSLHEWMVEKNGTLSKKSRLGEAFSYVLNQWDALCYYSDDGLAEAD
                     NNAAERALRAVCLGKKNFMFFGSDHGGERGALLYGLIGTCRLNGIDPEAYLRHILSVLP
                     EWPSNRVDELLPWNVVLTNK"
                     /name="IS66-like element ISEc23 family transposase"
     gene            2641..2895
                     /locus_tag="PIB86_RS25620"
                     /old_locus_tag="PIB86_25620"
     CDS             2641..2895
                     /locus_tag="PIB86_RS25620"
                     /old_locus_tag="PIB86_25620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication regulatory protein RepA"
                     /protein_id="WP_000083830.1"
                     /translation="MSQTENAVTSSSGAKRAYRKGNPLSDAEKQRLSVARKRASFKEVK
                     VFLEPKYKAMLMQMCHEDGLTQAEVLTALIKSEAQKRCM"
                     /name="replication regulatory protein RepA"
     gene            3133..3207
                     /gene="tap"
                     /locus_tag="PIB86_RS25625"
                     /old_locus_tag="PIB86_25625"
     CDS             3133..3207
                     /gene="tap"
                     /locus_tag="PIB86_RS25625"
                     /old_locus_tag="PIB86_25625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001370046.1"
                     /GO_process="GO:0006276 - plasmid maintenance [Evidence
                     IEA]; GO:0031556 - transcriptional attenuation by ribosome
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA leader peptide Tap"
                     /protein_id="WP_001365705.1"
                     /translation="MPGKVQDFFLCSLLLRIVSAGWCD"
                     /name="tap"
     gene            3200..4057
                     /gene="repA"
                     /locus_tag="PIB86_RS25630"
                     /old_locus_tag="PIB86_25630"
     CDS             3200..4057
                     /gene="repA"
                     /locus_tag="PIB86_RS25630"
                     /old_locus_tag="PIB86_25630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052675.1"
                     /GO_process="GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="incFII family plasmid replication initiator RepA"
                     /protein_id="WP_000130646.1"
                     /translation="MTDLHQTYYRQVKNPNPVFTPREGAGTLKFCEKLMEKAVGFTSRF
                     DFAIHVAHARSRGLRRRMPPVLRRRAIDALLQGLCFHYDPLANRVQCSITTLAIECGLA
                     TESAAGKLSITRATRALTFLSELGLITYQTEYDPLIGCYIPTDITFTSALFAALDVSEE
                     AVAAARRSRVVWENKQRKKQGLDTLGMDELIAKAWRFVRERFRSYQTELKSRGIKRARA
                     RRDADRERQDIVTLVKRQLTREIAEGRFTANREAVKREVERRVKERMILSRNRNYSRLA
                     TASP"
                     /name="repA"
     gene            4971..5240
                     /gene="yacA"
                     /locus_tag="PIB86_RS25635"
                     /old_locus_tag="PIB86_25635"
     CDS             4971..5240
                     /gene="yacA"
                     /locus_tag="PIB86_RS25635"
                     /old_locus_tag="PIB86_25635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015056448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin YacA"
                     /protein_id="WP_012881119.1"
                     /translation="MAQVNMSLRIDAELKDAFMAAAKSMDRNGSQLIRDFMRQTVERQH
                     NTWFRDQVAAGRQQLERGDVLPHDMVESSATAWRDEISRKVAGK"
                     /name="yacA"
     gene            5240..5518
                     /gene="yacB"
                     /locus_tag="PIB86_RS25640"
                     /old_locus_tag="PIB86_25640"
     CDS             5240..5518
                     /gene="yacB"
                     /locus_tag="PIB86_RS25640"
                     /old_locus_tag="PIB86_25640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013009346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin YacB"
                     /protein_id="WP_244449344.1"
                     /translation="MEIFWTILASQDRKRIREYIAEQNLMAAIELDERIGYSASSLAGQ
                     PYKGRNGRVEGTRELVIHPHFVLVYEVDSQWGKVYILRVLHTAQKWP"
                     /name="yacB"
     gene            5564..6412
                     /locus_tag="PIB86_RS25645"
                     /old_locus_tag="PIB86_25645"
     CDS             5564..6412
                     /locus_tag="PIB86_RS25645"
                     /old_locus_tag="PIB86_25645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001057990.1"
                     /GO_function="GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="WP_012881117.1"
                     /translation="MNNDELVTRRAQAIAEDRCFSKGRLRDEFRMKPAPGAEPVKWYKN
                     TYGGRFAVYRIADCVPMREKRPLTSKQQLAGQRLSVLSRLNSTSGRMARQAYDWLSLAP
                     LFLDTETTGLDNTAEALEIGLTDAAGQVVFETRLKPTVAIGAQAAAVHGISEQALCGAP
                     SWTDMARQLRHAIGDRPVIIFNARFDIRILKQTAAAHSDPADWLEEMTVYCAMELAAGY
                     YGATNRYGTISLASAASQAGLTWEGLAHSAIVDARMAAGVVNAIAAYHLELLQEQARLK
                     I"
                     /name="3'-5' exonuclease"
     gene            6529..7011
                     /locus_tag="PIB86_RS25650"
                     /old_locus_tag="PIB86_25650"
     CDS             6529..7011
                     /locus_tag="PIB86_RS25650"
                     /old_locus_tag="PIB86_25650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001402899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001311056.1"
                     /translation="MRNKTREAMRLFLGGRCYTAEKLEKDYLAEVANYSNDRWEAPQRA
                     ARLAASVKRYKTSEMLRFIFATIAYDPDPDLTPLTVRRLCKALFGRTGSQWLVVEVFGE
                     KGRQHRSADSNPEMVEKMAARYRHAAELHWSATLAEIERVKRLYQTKIKKSKKEVG"
                     /name="hypothetical protein"
     gene            complement(<7046..8068)
                     /gene="lamB"
                     /locus_tag="PIB86_RS25655"
                     /old_locus_tag="PIB86_25655"
                     /pseudo=""
     CDS             complement(<7046..8068)
                     /gene="lamB"
                     /locus_tag="PIB86_RS25655"
                     /old_locus_tag="PIB86_25655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709883.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="maltoporin LamB"
                     /name="lamB"
     gene            complement(<8117..8524)
                     /locus_tag="PIB86_RS25660"
                     /old_locus_tag="PIB86_25660"
                     /pseudo=""
     CDS             complement(<8117..8524)
                     /locus_tag="PIB86_RS25660"
                     /old_locus_tag="PIB86_25660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491235.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS903B family transposase"
                     /name="IS5-like element IS903B family transposase"
     gene            complement(8604..9479)
                     /locus_tag="PIB86_RS25665"
                     /old_locus_tag="PIB86_25665"
     CDS             complement(8604..9479)
                     /locus_tag="PIB86_RS25665"
                     /old_locus_tag="PIB86_25665"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032492044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extended-spectrum class A beta-lactamase
                     CTX-M-14"
                     /protein_id="WP_001617865.1"
                     /translation="MVTKRVQRMMFAAAACIPLLLGSAPLYAQTSAVQQKLAALEKSSG
                     GRLGVALIDTADNTQVLYRGDERFPMCSTSKVMAAAAVLKQSETQKQLLNQPVEIKPAD
                     LVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGPGGVTAFARAIGDETF
                     RLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRAQLVTWLKGNTTGAA
                     SIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQPQQNAESRRDVLA
                     SAARIIAEGL"
                     /name="extended-spectrum class A beta-lactamase CTX-M-14"
     gene            9907..11169
                     /locus_tag="PIB86_RS25670"
                     /old_locus_tag="PIB86_25670"
     CDS             9907..11169
                     /locus_tag="PIB86_RS25670"
                     /old_locus_tag="PIB86_25670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031587700.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISEcp1 family transposase"
                     /protein_id="WP_000608644.1"
                     /translation="MINKIDFKAKNLTSNAGLFLLLENAKSNGIFDFIENDLVFDNDST
                     NKIKMNHIKTMLCGHFIGIDKLERLKLLQNDPLVNEFDISVKEPETVSRFLGNFNFKTT
                     QMFRDINFKVFKKLLTKSKLTSITIDIDSSVINVEGHQEGASKGYNPKKLGNRCYNIQF
                     AFCDELKAYVTGFVRSGNTYTANGAAEMIKEIVANIKSDDLEILFRMDSGYFDEKIIET
                     IESLGCKYLIKAKSYSTLTSQATNSSIVFVKGEEGRETTELYTKLVKWEKDRRFVVSRV
                     LKPEKERAQLSLLEGSEYDYFFFVTNTTLLSEKVVIYYEKRGNAENYIKEAKYDMAVGH
                     LLLKSFWANEAVFQMMMLSYNLFLLFKFDSLDSSEYRQQIKTFRLKYVFLAAKIIKTAR
                     YVIMKLSENYPYKGVYEKCLV"
                     /name="IS1380-like element ISEcp1 family transposase"
     gene            <11181..11675
                     /locus_tag="PIB86_RS25675"
                     /old_locus_tag="PIB86_25675"
                     /pseudo=""
     CDS             <11181..11675
                     /locus_tag="PIB86_RS25675"
                     /old_locus_tag="PIB86_25675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052671.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="fertility inhibition protein FinO"
                     /name="fertility inhibition protein FinO"
     gene            11804..12016
                     /locus_tag="PIB86_RS25680"
                     /old_locus_tag="PIB86_25680"
     CDS             11804..12016
                     /locus_tag="PIB86_RS25680"
                     /old_locus_tag="PIB86_25680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001490517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANR family transcriptional regulator"
                     /protein_id="WP_001309245.1"
                     /translation="MNGTGRDSQNSGVWRYRQVGRRAVRLEVRGDWPGAAEAWLRAAQS
                     APRTDWQQFARKRAEHCHRRCRGRV"
                     /name="ANR family transcriptional regulator"
     gene            12261..12722
                     /locus_tag="PIB86_RS25685"
                     /old_locus_tag="PIB86_25685"
     CDS             12261..12722
                     /locus_tag="PIB86_RS25685"
                     /old_locus_tag="PIB86_25685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="WP_001233838.1"
                     /translation="MRKYIPLVLFIFSWPVLCADIHGRVVRVLDGDTIEVMDSRKAVRI
                     RLINIDAPEKKQDYGRWSTDMMKSLVAGKTVTVTYFQRDRYGRILGQVYAPDGMNVNQF
                     MVRAGAAWVYEQYNTDPVLPVLQNEARQQKRGLWSDADPVPPWIWRHRK"
                     /name="thermonuclease family protein"
     gene            12768..12977
                     /gene="hha"
                     /locus_tag="PIB86_RS25690"
                     /old_locus_tag="PIB86_25690"
     CDS             12768..12977
                     /gene="hha"
                     /locus_tag="PIB86_RS25690"
                     /old_locus_tag="PIB86_25690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_001298565.1"
                     /translation="MAKTKQEWLYQLRRCSSVNTLEKIIHKNRDSLLNSERESFNSAAD
                     HRLAELITGKLYDRIPKEIWKYVR"
                     /name="hha"
     gene            13015..13605
                     /locus_tag="PIB86_RS25695"
                     /old_locus_tag="PIB86_25695"
     CDS             13015..13605
                     /locus_tag="PIB86_RS25695"
                     /old_locus_tag="PIB86_25695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="WP_000766807.1"
                     /translation="MKLIIFILIVLIIAALLIRIILRSVNQHSPLLMQLHAAGIRTGDA
                     ERILSGGEYWQRQKTLLTEREVSFMKGLFRIVDMKRWYLCPQVRVADIVQLNGNIRPRS
                     RQWWQLFRMVSQWHVDVVIVERRSFSIVAAVELDDASHLRPERRRRDILLEEVLRQAGI
                     PLLRSHDARKLLQMTGEWLNTTGADQQSPEHRS"
                     /name="DUF2726 domain-containing protein"
     ARG             complement(8608..9479)
                     /name="blaCTX-M-14"
                     /gene="blaCTX-M-14"
                     /gene_name="extended-spectrum class A beta-lactamase
                     CTX-M-14"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          3231..4057
                     /name="IncFIA"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.517"
                     /coverage="97.0"
                     /evalue="0.0"
ORIGIN
        1 gcgccaacac agatcttcgt cacaattctc aagtcgctga tttcaaaaaa cgtaagcgta
       61 aactgaccgc cgtatgtagc catcagacga gaattggtaa cttagacgcc catctgatat
      121 agacggacat ctaagtatgg aattacagga ctggcgaaaa gaacctcgta aaaactattc
      181 gaatgaattc aaacttcgta tggtggaact ggcatcacaa cctggagctt gtgttgcaca
      241 gattgcacgt gaaaatggcg tcaatgataa tgttattttc aaatggctca ggctctggca
      301 gaacgaaggg cgtgtttcgc ggcgtcttcc ggtaacgacc tcttctgaca ctggcgttga
      361 attattacct gtagaaataa cgccggatga gcagaaagaa cctgtggcgg ccattgcgcc
      421 gtctttatcc acttccactc agaccagagt cagtgccagt tcctgcaagg tggaattccg
      481 tcacggtaac atgacgctgg aaaatccatc gccagagctg ctcacagtgt tgatccgtga
      541 actgaccggg aggggaagat gatctcactc ccatcaggta cccgtatctg gctcgttgcc
      601 ggcgttaccg atatgcgtaa atccttcaac ggactgggag aacaggtaca acatgtgctg
      661 aatgataatc ccttctccgg tcacctgttt atcttccgtg gccgacgggg tgacaccgtc
      721 aaaattcttt gggctgatgc tgatggtctg tgcctgttca ccaaacgcct ggaggaaggc
      781 cagtttatct ggcctgcggt acgtgacggc aaggtatcca ttacccgctc gcaactggca
      841 atgctcctcg ataagctgga ctggcgtcag ccaaaaacat ccagccgtaa ctcactgaca
      901 atgttgtaaa aaactcctga ccgcattata aaaacggtca tgagtcagaa atacctcatt
      961 cgcatcgcag agctggaaag gttgctctct gagcaggctg aagccctccg tcagaaagac
     1021 cagcaactga gtctggttga agagacggaa gccttcctgc gctctgcact gacacgtgcc
     1081 gaagaaaaga tcgaagaaga tgaacgggaa atagaacatc tgcgggctca gatagaaaaa
     1141 ctgcgccgga tgctgttcgg tacccgttct gaaaaactgc gtcgtgaagt tgaactggct
     1201 gaggctctgc tgaaacaacg tgaacaggac agcgatcgtt acagtgggcg ggaagacgat
     1261 cctcaggttc cccgccagtt gcgacagtcg cgccatcgtc gtccgttacc ggcacacctt
     1321 ccccgtgaaa tacaccgcct ggagccagaa gaaagctgtt gcccggagtg tggcggtgag
     1381 ctggattatc tgggggaagt cagcgctgaa cagctggaac tggtgagcag tgccctgaaa
     1441 gtgatccgca cagaacgggt aaaaaaagcc tgtacaaaat gtgactgtat tgttgaagca
     1501 ccggcgccgt cccgcccgat agagcgtggt atcgcgggcc ccggattact tgcccgcgtg
     1561 ttaacgggaa aatactgcga acatctgcca ctgtatcgtc agagtgaaat ctttgcccgc
     1621 cagggtgtcg aactgagccg ggccttactc tccaactggg ttgacgcgtg ctgccagtta
     1681 atgacaccgg tgaatgatgc cctgtaccgt tatgtaatga acacccgcaa ggttcacact
     1741 gatgacacac cggtaaaggt actggcaccg ggtcagaaaa aggcgaaaac agggcgtatc
     1801 tggacgtatg tccgggatga tcgcaatgtg ggttcgtcat ctcctccagc ggtctggttc
     1861 gcgtactcgc cgaaccggca ggggaaacac ccggagcaac acctccgccc cttccggggt
     1921 atcctgcagg cggatgcgtt cacaggttac gacaggttgt tcagtgcaga acgtgaaggt
     1981 ggtgcactga cagaagttgc gtgctgggcc catgcccggc gaaaaatcca cgatgtatac
     2041 atcagcagca aaagtgcgac ggcagaagaa gccctgaagc gaatcagtga actgtacgcc
     2101 atcgaggatg aaatacgggg attaccggag tcagagcgtc ttgccgtcag gcagcagcga
     2161 agcaaagtgt tactgacgtc gctgcatgaa tggatggtgg agaagaatgg tacgctgtcg
     2221 aaaaaatcca gactgggcga agcgttcagc tatgtactga atcagtggga tgccctctgt
     2281 tattacagtg atgacggtct ggcggaggcg gataataatg ctgcggaaag agcgcttcgt
     2341 gcagtctgtc tcggaaagaa aaactttatg ttctttggca gcgatcacgg cggcgagcgt
     2401 ggagcactgt tgtacgggct gatcggcacc tgccgtctga acggtatcga tccggaagcg
     2461 tatctgcgcc atatcctgag cgtactgccg gaatggcctt ccaaccgagt tgacgaactc
     2521 ctgccatgga acgtagtact caccaataaa taagcgtcaa tacggtgctc cgttgacgct
     2581 taccaaaaaa ctgtagtatc ctctgcgaaa cgatccctgt ttgagtattg aggaggcgag
     2641 atgtcgcaga cagaaaatgc agtgacttcc tcatctggcg caaaacgagc atacagaaag
     2701 gggaatccgc tttctgatgc agagaaacaa agattatcag tggcccgtaa aagagcttcg
     2761 ttcaaggaag taaaagtatt tcttgaacca aagtataagg ccatgctcat gcaaatgtgt
     2821 catgaagatg gtctgactca ggctgaagtt ctgaccgcac tgataaaaag tgaagcgcaa
     2881 aaacgatgca tgtgatgatg ggcttacatt cttgagtgtt cagaagatta gtgctagatt
     2941 actgatcgtt taaggaattt tgtggctggc cacgccgtaa ggtggcaagg aactggttct
     3001 gatgtggatt tacaggagcc agaaaagcaa aaaccccgat aatcttcttc aactttggcg
     3061 agtaagaaaa gattaccggg gcccacttaa accgtatagc caacaattca gctatgcggg
     3121 gagtatagtt atatgcccgg aaaagttcaa gacttctttc tgtgctcgct ccttctgcgc
     3181 attgtaagtg caggatggtg tgactgatct tcaccaaacg tattaccgcc aggtaaagaa
     3241 cccgaatccg gtgtttacac cccgtgaagg tgcaggaacg ctgaagttct gcgaaaaact
     3301 gatggaaaag gcggtgggct tcacttcccg ttttgatttc gccattcatg tggcgcatgc
     3361 ccgttcgcgt ggtctgcgtc gacgcatgcc accagtgctg cgtcgacggg ctattgatgc
     3421 gctcctgcag gggctgtgtt tccactatga cccgctggcc aaccgcgtcc agtgctccat
     3481 caccacgctg gccattgagt gcggactggc gacggagtct gctgccggaa aactctccat
     3541 cacccgtgcc acccgggccc tgacgttcct gtcagagctg ggactgatta cctaccagac
     3601 ggaatatgac ccgcttatcg ggtgctacat tccgaccgat atcacgttca catctgcact
     3661 gtttgctgcc ctcgatgtat cagaggaggc agtggccgcc gcgcgccgca gccgtgtggt
     3721 atgggaaaac aaacaacgca aaaagcaggg gctggatacc ctgggcatgg atgaactgat
     3781 agcgaaagcc tggcgttttg ttcgtgagcg ttttcgcagt tatcagacag agcttaagtc
     3841 ccggggaata aagcgtgccc gtgcgcgtcg tgatgcggac agggaacgtc aggatattgt
     3901 caccctggtg aaacggcagc tgacgcgcga aatcgcggaa gggcgcttca ctgccaatcg
     3961 tgaggcggta aaacgcgaag ttgagcgtcg tgtgaaggag cgcatgattc tgtcacgtaa
     4021 ccgtaattac agccggctgg ccacagcttc cccctgaaag tgacctcctc tgaataatcc
     4081 ggcctgcgcc ggaggcttcc gcacgtctga agcccgacag cgcacaaaaa atcagcacca
     4141 catacaaaaa acaacctcat catccagctt ctggtgcatc cggccccccc tgttttcgat
     4201 acaaaacacg cctcacagac ggggaatttt gcttatccac attaaactgc aagggacttc
     4261 cccataaggt tacaaccgtt catgtcataa agcgccatcc gccagcgtta cagggtgcaa
     4321 tgtatctttt aaacacctgt ttatatctcc tttaaactac ttaattacat tcatttaaaa
     4381 agaaaaccta ttcactgcct gtcctgtgga cagacagata tgcacctccc accgcaagcg
     4441 gcgggccccg accggagcca ctttagttac aacacacaaa aacaacctcc agaaaaaccc
     4501 cggtccagcg cagaaccgaa accacaaagc ccctccctca taactgaaaa gcggccccgc
     4561 cccggcccaa agggccggaa cagagtcgct tttaattatg aatgttgtaa ctacatcttc
     4621 atcgctgtca gtcttctcgc tggaagttct cagtacacgc tcgtaagcgg ccctcacggc
     4681 ccgctaacgc ggagatacgc cccgacttcg ggtaaaccct cgtcgggacc actccgaccg
     4741 cgcacagaag ctctatcatg gctgaaaacg ggtatggctt agcaggactg gggatgggta
     4801 aggtgaaatc tatcaatcag taccggctta cgccgggctt cggcggtttt actcctgtgc
     4861 catatgcaac aacggagtgc cgccttccat gccgctggcg cggcatatcc tggtgacgat
     4921 atctgaatcg ttatatactg tgtatatacg tagtaatgac gaggtgataa atggcacagg
     4981 ttaatatgag tttaagaatc gacgctgaac tgaaggatgc ttttatggcc gctgcaaaaa
     5041 gcatggaccg taatggctct cagttaattc gggattttat gcgccagacc gttgaacggc
     5101 agcataatac ttggttccgt gaccaggttg cggcaggacg tcagcaactc gaacgcggcg
     5161 atgtgcttcc ccatgatatg gtcgaatcct ccgctactgc atggcgggat gaaataagca
     5221 ggaaggtcgc cggtaaatga tggagatatt ctggaccata ctggccagcc aggacaggaa
     5281 gcgcattcgt gagtatattg cggagcagaa cctgatggct gccattgaac tggacgaacg
     5341 gattggttat tcagccagca gcctggccgg gcagccgtat aaaggccgca acggtcgtgt
     5401 ggaaggtacc cgggaactgg ttattcaccc gcattttgtt ctggtttatg aggtcgacag
     5461 ccagtgggga aaagtgtata tcctgcgagt attgcatact gcacagaagt ggccatagag
     5521 gggctgtccg gatataaaaa cgtctgacgg agatgcaaga accatgaata atgatgagct
     5581 ggtcaccaga cgtgcgcagg cgattgccga agacaggtgt ttctcgaaag gacgtctgcg
     5641 cgatgaattc agaatgaagc cagcccccgg tgctgagccg gttaagtggt ataaaaatac
     5701 ttatggtggc aggttcgctg tataccgaat tgcagactgt gttccgatgc gtgagaaacg
     5761 ccctctgacg agtaaacaac agctggctgg ccagcggctt tccgttttat cccggctaaa
     5821 cagcaccagt ggccggatgg cacggcaggc atatgactgg ctgagtctgg caccactctt
     5881 tctggatact gaaacgacag gactggataa taccgcggaa gccctggaaa tcggcctgac
     5941 cgatgcggcc ggtcaggtgg tatttgaaac caggctgaag cccacggtcg ccatcggggc
     6001 gcaggccgcc gccgtgcatg gtatcagtga gcaggctctt tgcggcgcac catcatggac
     6061 agatatggcg cggcaactgc ggcatgcaat cggagatcga ccagtaatta tctttaatgc
     6121 ccggttcgac atccgcattc tgaaacagac tgcggccgca catagcgatc cggctgactg
     6181 gctggaagaa atgacggtat attgtgcgat ggagctggct gcaggatatt atggggccac
     6241 caaccgctat ggcacgattt cactggccag tgctgccagc caggccggac tgacctggga
     6301 agggctggca cactcagcga tcgtcgacgc acggatggcg gcaggggtgg taaacgctat
     6361 tgctgcatat catctggaac tgctgcagga acaggcacgg ctgaaaatct gaccgcctgg
     6421 cctgtatacc gcaatcattt acgttatcca gacgtaaatc cgccgcttgt tactgtcagc
     6481 atgttaatgc taatgtatgc gtacattagc attaatgagg gatgatatgt gagaaataaa
     6541 accagggagg ccatgcggct ttttttaggc ggcaggtgct acacggctga aaaacttgaa
     6601 aaggattatc tggctgaagt ggctaattac agtaacgacc gctgggaagc accgcaacgt
     6661 gccgcacgcc tggctgccag cgtaaagcgt tacaagacat cagaaatgct gcgctttatt
     6721 tttgctacca ttgcctatga tcccgatcca gatttaaccc cgctgactgt gagacgtttg
     6781 tgcaaggcat tgttcggcag aaccggaagc cagtggctgg ttgttgaagt ttttggggag
     6841 aaggggcgtc agcaccgcag cgcggacagc aatccggaga tggtggaaaa aatggctgcc
     6901 agatatcgtc atgccgccga actacactgg tccgcaacgc tggcagaaat tgaacgggta
     6961 aagcggcttt atcagacgaa aattaagaaa tccaaaaaag aagtgggttg actgccattg
     7021 ttattctttt ccttcatcat taatgctggg attcgacgtt gtcgtagccg atttccatca
     7081 cggtgctcat gattggcgtc cacttgtaca tcgggcgaat accgacggtc caccacttgg
     7141 tgccgttgtc gttatcccag ttgatatcct ggtacatacc cacgtacatc atgtcccagt
     7201 tgtcgcccat ggagatcgct ccgtggtcga ggatacgcag catgtgaccg ttgttgttga
     7261 tattgtaggc aaatttttcg ttatcaaacg cgacgccaga accctgcgac agacctttac
     7321 cctgcgaggt catcgagtca gtagcgtact gaacaacaaa cttgttaaag cccttcagga
     7381 cactctgagt atgttcagca gtgaacaacc agccgtcttt cgatgcgcca tcaaccagac
     7441 gatagttatc acgcaggttg gcacgaccgt agtcgacacc cagttctaat gtgccgcccg
     7501 gattgatttc catctgcgct aaacgcacat cgaaaacgtc gttcgcggtt tcgttggtat
     7561 agtcataaat attgttgctg gcgaaagagg aagaaccacc tgcttcagag gagcgggttg
     7621 ctgccagaga gagtttaccg aagccaacat cgatgttttc cagaccggca ccaggaccag
     7681 aaatatccca gtagtagaag tcgatcatat gaacgtcatg acgttggtag aagcgcttac
     7741 ctgcccagat ggtggagcct ggcagccatt cgatcaggtt tttaccctgc acgtttgctt
     7801 cacggaaggc cggatcggta gcttcccagt cattctgttg tgcgacggaa taggccacgt
     7861 tagtgtcgaa atagaagctc ttatcgccct ctttccacac ttcctgaccc aattttaatt
     7921 cagcataagt ttcacattcg ttgccaagac ggtatttact ttgagcaccg gtagtctgga
     7981 aacactgttg ttcaccgccg ctacctgtcc agccaatacc ggaacgtgca tagccgtgga
     8041 aatcaacagc cattgcctga gcagacatta cgcccgctgc gacggcaacc gccagaggaa
     8101 gtttgcgcag agtaatcttg actttccact cgccttcacc gaagaccttc agcccggtgg
     8161 aatcaattac caggtgtgcg atttcacccc gggtgggcgt tttgaaactg atattaaccg
     8221 actttgcccg cctgctgaca cagctgtaat ccgggcagcg tagcggaacg ttcatcagag
     8281 aaaaaatgga atcaataaag ccctgcgcag cgcgcagggt cagcctgaat acgcgtttaa
     8341 tgaccagcac agtcgtgatg gcaaggtcag aatagcgctg aggtctgcct cgtgaagaag
     8401 gtgttgctga ctcataccag gcctgaatag cttcatcatc cagccagaaa gttatggagc
     8461 cacggttgat gagggcttta ttgtaggtgg gccagttggt gattttgaac ttttgctttg
     8521 ccacggaacg gtctgcgttg tcgggaagat acgtgatctg atccttcaac tcagcaaaag
     8581 ttcgatttat tcaacaaaac cagttacagc ccttcggcga tgattctcgc cgctgaagcc
     8641 agcacatcgc ggcggctctc tgcgttctgt tgcggctggg taaaataggt caccagaacc
     8701 agcggcgcac gaccctgcgg ccagatcacc gcaatatcat tggtggtgcc gtagtcgccg
     8761 ctgccggtct tatcacccac agtccacgac gtcggtaagc cggcccgaat gctggctgcg
     8821 ccggtcgtat tgcctttgag ccacgtcacc aactgcgccc gctgggtttc gcccagcgca
     8881 tgacccagcg taagctgacg caacgtctgc gccatcgccc gcggcgtggt ggtgtctctc
     8941 gggtcgccgg gaatggcggt attcagcgta ggttcagtgc gatccagacg aaacgtctca
     9001 tcgccgatcg cgcgggcaaa agccgtcacg cctcccgggc caccgagctg ggcaatcaat
     9061 ttgttcatgg cggtattgtc gctgtactgc aacgcggccg cgctcagttc tgccagcgtc
     9121 attgtgccgt tgacgtgttt ttcggcaatc ggattgtagt taaccagatc ggcaggcttg
     9181 atctcgacag gctgattaag cagctgcttt tgcgtttcac tctgcttaag caccgccgcg
     9241 gccgccataa ctttactggt actgcacatt ggaaagcgtt catcaccgcg ataaagcacc
     9301 tgcgtattat ctgcggtatc gatgagcgcg acgcccagcc gccctccgct gcttttctcc
     9361 agcgccgcca gcttttgctg caccgcactc gtctgcgcat aaagcggcgc gctgcccagc
     9421 agcagcggaa tgcacgccgc cgccgcgaac atcatccgtt gcactctctt tgtcaccatc
     9481 tcaaactccc aatacggtca atccgtgtta catcagtatt ccctaaattc cacgtgtgtt
     9541 ttttattagc ttcaaaaatc actatttcac gaagaattta gactgcttct cacacattgt
     9601 aacattattt acaaccacct ttcaatcatt tttgataaat cattgatttc atctttgctg
     9661 caatgatact taataaactc tgcaagttat ccacagagca acactcaatt ttattgatga
     9721 cctagattct acgtcagtac ttcaaaaagc ataatcaaag ccttgataaa tatgcattcc
     9781 ttcgaaattc agctttcacc cattgggtga aagaaaagtg ctcaaaaata tgttaaatta
     9841 tcagctttta tgactcgata tatggtaaaa taatagtaag aaaagtagta aaaaggggtt
     9901 ctaattatga ttaataaaat tgatttcaaa gctaagaatc taacatcaaa tgcaggtctt
     9961 tttctgctcc ttgagaatgc aaaaagcaat gggatttttg attttattga aaatgacctc
    10021 gtatttgata atgactcaac aaataaaatc aagatgaatc atataaagac catgctctgc
    10081 ggtcacttca ttggcattga taagttagaa cgtctaaagc tacttcaaaa tgatcccctc
    10141 gtcaacgagt ttgatatttc cgtaaaagaa cctgaaacag tgtcacggtt tctaggaaac
    10201 ttcaacttca agacaaccca aatgtttaga gacattaatt ttaaagtctt taaaaaactg
    10261 ctcactaaaa gtaaattgac atccattacg attgatattg atagtagtgt aattaacgta
    10321 gaaggtcatc aagaaggtgc gtcaaaagga tataatccta agaaactggg aaaccgatgc
    10381 tacaatatcc aatttgcatt ttgcgacgaa ttaaaagcat atgttaccgg atttgtaaga
    10441 agtggcaata cttacactgc aaacggtgct gcggaaatga tcaaagaaat tgttgctaac
    10501 atcaaatcag acgatttaga aattttattt cgaatggata gtggctactt tgatgaaaaa
    10561 attatcgaaa cgatagaatc tcttggatgc aaatatttaa ttaaagccaa aagttattct
    10621 acactcacct cacaagcaac gaattcatca attgtattcg ttaaaggaga agaaggtaga
    10681 gaaactacag aactgtatac aaaattagtt aaatgggaaa aagacagaag atttgtcgta
    10741 tctcgcgtac tgaaaccaga aaaagaaaga gcacaattat cacttttaga aggttccgaa
    10801 tacgactact ttttctttgt aacaaatact accttgcttt ctgaaaaagt agttatatac
    10861 tatgaaaagc gtggtaatgc tgaaaactat atcaaagaag ccaaatacga catggcggtg
    10921 ggtcatctct tgctaaagtc attttgggcg aatgaagccg tgtttcaaat gatgatgctt
    10981 tcatataacc tatttttgtt gttcaagttt gattccttgg actcttcaga atacagacag
    11041 caaataaaga cctttcgttt gaagtatgta tttcttgcag caaaaataat caaaaccgca
    11101 agatatgtaa tcatgaagtt gtcggaaaac tatccgtaca agggagtgta tgaaaaatgt
    11161 ctggtataat aagaatatca tcccggaaaa ccatcatcaa tgtcaccacg ccaccaaaat
    11221 ggaaggtgaa aaagcagaaa ctggcggaga aggctgcccg ggaagcagag ctgacagcaa
    11281 aaaaagcgca ggccagacag gcgctgtcca tttatctgaa cctgcccaca ctggatgaag
    11341 ccgtgaacac cctgaaaccc tggtggccgg gattatttga cggtgacaca ccccggcttc
    11401 tggcctgcgg tatccgggac gtgttactgg aagacgtggc gcagcggaat atcccgctct
    11461 cgcataaaaa actgcgcagg gcgctgaagg ccatcacccg ttcagaaagc tatctgtgtg
    11521 ccatgaaagc cggtgcctgc cggtatgaca cggaagggta tgtgacggag catatttctc
    11581 aggaggaaga agtgtatgcg gcagagcgtc tggataaaat ccgccgccag aaccggataa
    11641 aggcagaact tcaggccgtg cttgatgaac aataaaaaag cctccttcac actaaaggag
    11701 gcggaaaaat aaggcttctc tgaaaccttc ttccataccc ggcagaagaa ggttataaaa
    11761 atttataaca cattcaccgg cctggattaa agggggaagg aaaatgaacg gaacagggcg
    11821 tgattcgcaa aactccgggg tatggcgcta ccggcaggtc ggacgccggg ctgtccggct
    11881 ggaagtcagg ggggactggc cgggagccgc tgaggcatgg ctacgggctg cgcagtctgc
    11941 tccccggaca gactggcagc agtttgcccg aaaaagggct gaacactgcc accggcgctg
    12001 ccggggaagg gtgtaacgaa aaagcagcct tcattactcc agggattcag aaggctgaat
    12061 aatgcatgag atttgctttt tttaatatcc ggtcgggaag tatgaccgga cagttctgag
    12121 tagcacagag ttttttccgt attaagtcgt gattttatat tttgtgatta atttcacaaa
    12181 ataaggtgtt attcagtgtg tgctgcgata ttcaggatta cctgaaatac aggtgccatt
    12241 tatctgatat ggagaataac atgaggaaat atattccact ggtattattt atcttttcat
    12301 ggccggtatt gtgtgcagat attcatggac gggttgttcg tgtactggac ggtgatacca
    12361 tcgaggtcat ggactcacgg aaggcagtgc ggatcaggct gataaatatt gatgcaccgg
    12421 aaaagaaaca ggattatggc cggtggtcaa cggacatgat gaaatcactg gttgcaggaa
    12481 aaacggttac cgtcacatat tttcagcgag atcgttatgg tcgtattctc gggcaggttt
    12541 atgcaccaga cggaatgaat gttaatcagt ttatggtccg ggccggggct gcctgggtat
    12601 atgagcagta caacacagat cccgtgctgc ctgtccttca gaacgaagcc agacaacaaa
    12661 aacgtgggct ctggtcagat gctgatccgg ttcccccctg gatatggaga caccgtaaat
    12721 aaagcgatgg caatcttatc attcatctgt tctcagcggg aataaaaatg gcgaaaacaa
    12781 aacaggaatg gctgtatcag ttacggcgat gttcatcagt caatacgctg gaaaaaatta
    12841 ttcataaaaa cagagacagt ttattaaaca gtgaacgtga atcatttaat tcagcagcag
    12901 accaccggtt agcggaatta atcaccggaa agttatatga caggatacca aaagagatat
    12961 ggaaatatgt aaggtaataa ttcagcataa ttaattacca ggagcagata aacaatgaag
    13021 ctgattattt ttattcttat tgttctgatt attgcagcgt tacttatccg gattatcctc
    13081 agaagtgtaa atcagcattc tcctttgctg atgcaattgc atgcggcagg tatacggacc
    13141 ggtgatgcag agcgaatact gtccggcggt gaatactggc aacgtcagaa gacgctgctg
    13201 acagaaaggg aagtcagttt tatgaaagga ctgttcagaa ttgtggatat gaagcggtgg
    13261 tatctgtgtc cgcaggtacg ggtcgcggat atcgtccagc tgaacgggaa tatccggcca
    13321 cgatcacgcc agtggtggca gttattcagg atggtgtctc agtggcatgt tgatgtggtt
    13381 atcgttgagc ggcgttcgtt cagtattgtt gcagcagtag agctggatga tgccagccat
    13441 ttacgaccgg aacgcagacg ccgggatatt cttctggaag aggttctgag gcaggctggt
    13501 attccgttgc tcagaagcca cgatgccaga aaactgctgc agatgaccgg agaatggctg
    13561 aatacaacag gggctgatca gcagtccccg gaacatcgta gctgacgcct tcgcgttgct
    13621 cagttgtcca accccggaaa cgggaaaaag caagttttcc ccgctcccgg cgtttcaata
    13681 actgaaaacc atactatttc acagtttaaa tcacattaaa cgacagtaat ccccgttgat
    13741 ttgt
//
