LOCUS       NZ_CP116128            30896 bp    DNA     circular CON 25-FEB-2024
DEFINITION  Escherichia coli strain DETEC-P666 plasmid pDETEC36, complete
            sequence.
ACCESSION   NZ_CP116128
VERSION     NZ_CP116128.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN31988472
            Assembly: GCF_027944795.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 30896)
  AUTHORS   Moran,R.A., Baomo,L., Doughty,E.L., Guo,Y., Ba,X., van Schaik,W.,
            Zhuo,C. and McNally,A.
  TITLE     Extended-spectrum beta-lactamase genes traverse the Escherichia coli
            populations of ICU patients, staff and environment
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 30896)
  AUTHORS   Moran,R.A., Baomo,L., Doughty,E.L., Guo,Y., Ba,X., van Schaik,W.,
            Zhuo,C. and McNally,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JAN-2023) Institute of Microbiology and Infection,
            University of Birmingham, Institute of Microbiology and Infection,
            Birmingham B15 2TT, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 10x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/25/2024 02:06:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,170
            CDSs (total)                      :: 5,049
            Genes (coding)                    :: 4,837
            CDSs (with protein)               :: 4,837
            Genes (RNA)                       :: 121
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 212
            CDSs (without protein)            :: 212
            Pseudo Genes (ambiguous residues) :: 0 of 212
            Pseudo Genes (frameshifted)       :: 83 of 212
            Pseudo Genes (incomplete)         :: 145 of 212
            Pseudo Genes (internal stop)      :: 42 of 212
            Pseudo Genes (multiple problems)  :: 52 of 212
            Pseudo Genes (short protein)      :: 3 of 212
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP116128.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..30896
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="DETEC-P666"
                     /isolation_source="ICU patient oral swab"
                     /db_xref="taxon:562"
                     /plasmid="pDETEC36"
                     /geo_loc_name="China: Guangzhou"
                     /collection_date="2019-09-10"
     gene            join(30839..30896,1..443)
                     /gene="ddp1"
                     /locus_tag="PIB57_RS25450"
                     /old_locus_tag="PIB57_25455"
     CDS             join(30839..30896,1..443)
                     /gene="ddp1"
                     /locus_tag="PIB57_RS25450"
                     /old_locus_tag="PIB57_25455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 1"
                     /protein_id="WP_063270188.1"
                     /translation="MKQIKFRVSDDELKLAEHNAILSGFTSVNAFAKHNVLNIETKPVN
                     IPVNNEAAKLVSVRLYPHEIELVKRNAVLHGMSMSREIAIRVRQSLLKNEVCLYPDEIK
                     EIRRLKTEINKLGRNVHYIISGDRFCIVNDPEFRKEINDALNICQQTAKQLETLVTAVV
                     NRF"
                     /name="ddp1"
     gene            455..1684
                     /gene="taxC"
                     /locus_tag="PIB57_RS25455"
                     /old_locus_tag="PIB57_25460"
     CDS             455..1684
                     /gene="taxC"
                     /locus_tag="PIB57_RS25455"
                     /old_locus_tag="PIB57_25460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA relaxase/nickase TaxC"
                     /protein_id="WP_001694183.1"
                     /translation="MGVHVEQEYRIKRAKSTGRDPKIPKLSGRHLHASKSAFNHKVRHG
                     ADKKAYNWTPTKEVTFKITGSGKTPAGIKNGIDYITRNGELEAYYYDGDGREKTGCGRN
                     FNAGITSGMTEDNDYSKTYRGENIDHVKNMVFSPPPEAGVSREDALKATVEFLKETYPN
                     HAFVAVYHDDKEDHPHVHVNIKLRDEETGRRLRLTKSETRKFRNGFHRKLKGMGYDVTA
                     TWKKDPERKREIERLQAENPKRLRNVYKVVDFGETSYQNKAGEKRTPFLTYETLKGGKQ
                     VTIWGKDLKNHFESEKLQPGTLIKVKKLAPTLVRSPMFNDDGTVAGYRETHRNNWQIEN
                     IALERNRERQVHERETRQPEESDVKKQLSRKHEQGHNIGFALEHGFTKDSEEHKKLRIQ
                     QERNWKGLGF"
                     /name="taxC"
     gene            1761..2054
                     /locus_tag="PIB57_RS25460"
                     /old_locus_tag="PIB57_25465"
     CDS             1761..2054
                     /locus_tag="PIB57_RS25460"
                     /old_locus_tag="PIB57_25465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134733.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO:0016987 - sigma factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_000134733.1"
                     /translation="MTEHDAICISALHQIFSDEEHLSEQQKDIILMYAYGYTLNEIADF
                     KGLKPSTVRKYLDSVRAELGGVSLAGIRTLVLIRTNALLVSSLSRISERGNL"
                     /name="sigma factor-like helix-turn-helix DNA-binding
                     protein"
     gene            2051..2266
                     /locus_tag="PIB57_RS25465"
                     /old_locus_tag="PIB57_25470"
     CDS             2051..2266
                     /locus_tag="PIB57_RS25465"
                     /old_locus_tag="PIB57_25470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000760375.1"
                     /translation="MKKYLLFALPFFVVGCSEEVKSVDWWGQHLTEAKQKQAECEKSGS
                     DSQNCKNVKQALFIQSQKDAPVPTFD"
                     /name="EexN family lipoprotein"
     gene            2622..3242
                     /locus_tag="PIB57_RS25470"
                     /old_locus_tag="PIB57_25475"
     CDS             2622..3242
                     /locus_tag="PIB57_RS25470"
                     /old_locus_tag="PIB57_25475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_000157549.1"
                     /translation="MASLFPALLLCAASVHPDTINDIARVESGFNPYAVAEIIPERERG
                     SYGKSVISHMPKSKEEALTVIREIENRKRRYSVGLMQITSSNFSFYSTSAEKLLDSCEN
                     LSVFEKIIVDCYKRGRSLENALSCYYTGNFSNGKRKEKEFNNTSYVERIGYTGNEKKYV
                     VPGTRSNGGEQRKNRSHNASVIWPETILKSAFVDNSHPTKVIN"
                     /name="lytic transglycosylase domain-containing protein"
     gene            3256..3582
                     /locus_tag="PIB57_RS25475"
                     /old_locus_tag="PIB57_25480"
     CDS             3256..3582
                     /locus_tag="PIB57_RS25475"
                     /old_locus_tag="PIB57_25480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000008647.1"
                     /translation="MSFKKSVCNRISSSVTAVMQRKNKVVMAVAGATVASPAFADGFSK
                     AETLLEKVKTGLSGLSLVTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAEVAS
                     MMVN"
                     /name="TrbC/VirB2 family protein"
     gene            3601..6348
                     /locus_tag="PIB57_RS25480"
                     /old_locus_tag="PIB57_25485"
     CDS             3601..6348
                     /locus_tag="PIB57_RS25480"
                     /old_locus_tag="PIB57_25485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="WP_000105985.1"
                     /translation="MSTLYKAMTRPAMYVGVPVVPLTVVAGALFLAGVYISKLIWLAIP
                     VAVFVLRMITKQDDHIFNLYFLKLKMLGNSVCNRFFGARAFLSGQYEAVEIDEFVNAMK
                     LNERITTGKYIPYSSHVDKNIVKTKNGDYVATWQLMGINFESISAEMLETIDSQVATLV
                     RSFSGLPVSFYNHSCRASFYDAFTTKSGNKYADIISDCYYGSMKKNKFKGNTLYFTLIY
                     RPDGRVEKLEKRKKSIKEKKDDINIHVKRMNEMINTFSGALDKFTCKLLGMYEENGKVF
                     SSQLSFYNYLLTGKLQKIRVTDSPVYNVLGGVDVFFNHDTGQICRIDGNKFFRSIEIKD
                     FCSETASGVFDVLQYSDADYIITHSYTSMSKSEALSTIKRAEKQLKSTEDDAVTQLQEL
                     EKAKNDIVSGDISFGYYHFTLMVMADSIRELDESVSKITADFTDLGIIPALSTMSLPAA
                     YFAQLPAVFHLRPRLSPVSNVNFVELASFHNFYQGKRDKNCWTEAVAILKTPSKQAYYL
                     NLHNSVLFKDETGEKNLANTKVIGTAGSGKTMFLSYLACSLQKYNNPETFADSAKNKKL
                     TCVFLDKDRGAELCIRMLGGEYYTVKSGEPTGWNPFALEATKRNRIFVKQLMEILCTRN
                     GERLSTRERLLISESVDAVMDFPPGEMREYGITRMLEHLMQRDDRDEQENGIILRLSQW
                     ANGQAHGWVFDNAKDTFNIQHVNNFGIDGTEFLDDPMVCAPITFYLLYRITQLLDGRRL
                     VIFLDEFWKWLQDEAFSDFVYNKLKTIRKLNGLVIPATQSPDEILKNKISRAVVEVCST
                     SIYLANPDADYNDYVEGLKLTPEEFNIVKNLDPMSRQFLIKKSSLKKGDGKSFSALATL
                     DLSGLGGYLKILSASADNLEIFESIYHEGMEPDDWVPEYLERAI"
                     /name="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
     gene            6360..7076
                     /locus_tag="PIB57_RS25485"
                     /old_locus_tag="PIB57_25490"
     CDS             6360..7076
                     /locus_tag="PIB57_RS25485"
                     /old_locus_tag="PIB57_25490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000832283.1"
                     /translation="MKRVKTLMLISLLTASFYSSAGIPVAIDASPEWAVEAARWTERLK
                     QWSETAQHYQSQIQAYKDQLATATGIRNIAAFTNELSNLQSELTNIYKQGNSYISDFTS
                     NPEGALSSQAKNLFSKYGAFDMCNTGYERNDNLCKARIVSTAASIEQGNEINKQLSSAM
                     SQIQSLSSRIEASKDIKESQDLANALQAQSLKMQAIKMQYDVWNNKNKADHEMLVTQEQ
                     EAFIKQQKEAEPLTFD"
                     /name="type IV secretion system protein"
     gene            7088..8182
                     /locus_tag="PIB57_RS25490"
                     /old_locus_tag="PIB57_25495"
     CDS             7088..8182
                     /locus_tag="PIB57_RS25490"
                     /old_locus_tag="PIB57_25495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001677777.1"
                     /GO_process="GO:0030255 - protein secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000046889.1"
                     /translation="MAQGFFVKYNSTVMDSVDKISSSYQTQFANDIMSLATVSVTLYVL
                     WKGYQILASKTQTPLQDLVWDLSKFAIIIMFITNADGYLTAATDALQGMKDGFSGGVSV
                     WQTLDNLWKSTQNLGAEIYSLDKSTYVKDQGVVGQFLIWTGSLILMAVSVVVFLTADVT
                     MKLLIITAPIFIFCLMFGFIRSMFNNWLQSLFSSILTVLFASLVIRIAMDFQGMILSHA
                     IRAAQTGNVNLVSTGAMGFMAGFLGALLVLIAKGFAVQLAGAGVEGAVQGAAMMGLGAA
                     GMATGKSLMLGGRAGLGFGLGMAGRTGMNSLSGKAGNLMGRGARTAAEWAGEKGYQALA
                     PTGALGMKARRLASLEKARARNAA"
                     /name="type IV secretion system protein"
     gene            8679..9365
                     /locus_tag="PIB57_RS25495"
                     /old_locus_tag="PIB57_25500"
     CDS             8679..9365
                     /locus_tag="PIB57_RS25495"
                     /old_locus_tag="PIB57_25500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_021548634.1"
                     /translation="MSEKIEKKIETAKSFERQLYAENERSKKNAWRVAAAASLLSLCLG
                     AAICVLVPLKEKELAIVAVGEKTGRTELITQVKQEKILQSEALGRYFVNTYITLREGYN
                     YPSLQYDYETVQLYSSNTVKDDYLRLYNSDMAPDKIYHNNGSYVAIEVISNIISDATAP
                     DKLASVRFKKTTRNFTTGQVSVSYWTARVTYRFEPEKSVKSSSRELNPLGFTVTSYQTD
                     REVRGE"
                     /name="type IV secretion system protein"
     gene            9362..10270
                     /gene="virB9"
                     /locus_tag="PIB57_RS25500"
                     /old_locus_tag="PIB57_25505"
     CDS             9362..10270
                     /gene="virB9"
                     /locus_tag="PIB57_RS25500"
                     /old_locus_tag="PIB57_25505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_271291425.1"
                     /translation="MMKKLFIATCLLLPGLVYSAATPLPSGFDARMQTVSYNGANTTVI
                     RSKTGFLTSVVFDEGEAVISAKAGFPAGWEITTDDNVVYINPRPVVQEQEGDEGEKLKK
                     VFQPTEKEWDTNLFVRTTKRIYSLDLILLSEEKQAQPAYVVQFRYPSEIAKKNAEEVRL
                     AKEKQEKLRQKKLISESFEKADAPKNWNYFMRVNEKYDSRRIAPDFAYDNGIFTFLGFN
                     SGKVFPAPFAVRDDQEQTLAFNVETKGKYKIMVIHNVNDKFVLRYGNSVVGVVNKSFGK
                     VLTDQRNTSSPAVERVEVNND"
                     /name="virB9"
     gene            10263..11381
                     /gene="virB10"
                     /locus_tag="PIB57_RS25505"
                     /old_locus_tag="PIB57_25510"
     CDS             10263..11381
                     /gene="virB10"
                     /locus_tag="PIB57_RS25505"
                     /old_locus_tag="PIB57_25510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_000131269.1"
                     /translation="MTDMKKTDDLVDDANQSKLESKPVHDIGDIRNKNNRMRSGFLFGL
                     MAVLVIGIFALKTYKNYFADDQQKASESTGDTSISQVSKIRTGLGQNFDPVENKAIINP
                     GATGSGNTVSDGHKEVPQEGFRKYLSIPVADQGGSQTGASGSSRTSQTSEPQEERKESK
                     ENVPGKSGMKVTAIKLNPDLYIEENRLIPCALTTRFVSDVAGRISCVFTEDVWSANHHT
                     KLLEQGTKAFGRYQTGTLNHGQGRMFVMWEQLRTPDNKRIDMVNTAAAGPLGEAGIDGW
                     IDSHFWERFGGSLMLSMVQDVAAAAADNAPGKDRNVDYTENSRQAMAEMAKVALENSIN
                     IPPTMYKNQGDIITIMVGEDIDFSDIYELKVK"
                     /name="virB10"
     gene            11383..12411
                     /gene="virB11"
                     /locus_tag="PIB57_RS25510"
                     /old_locus_tag="PIB57_25515"
     CDS             11383..12411
                     /gene="virB11"
                     /locus_tag="PIB57_RS25510"
                     /old_locus_tag="PIB57_25515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401678.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_001014667.1"
                     /translation="MNGVIPVSISNKSLDFYKNQVFQSFLDIEGLTEIAVNRPGEIWTE
                     INGDWTFHNNDSVTFDFCKRFSQTLASFRGDEIGDTKPLLSATLESGERVQVVFPPACE
                     RNTISITIRKPSTRQITHKEYVANGFYDYVQSGKKHRTYDDELLDLFRARNIAAFMELA
                     VAAGKTIVFAGATGSGKTTYMKSLIDFIPLNTRLITIEDAEEIKFFIHKNYVHLFYPSE
                     SGSDSGSIITAAKLIKSCLRMKPDRILLAEIKGGDAWDFVKVAGSGHSGSMTSIHAASA
                     KDAIIQMVTKCYQNRECQNLPFDVLRKIIMDSIDIVVHVGRDGVVRHMSDIYYKGAECE
                     NF"
                     /name="virB11"
     gene            12398..14260
                     /gene="taxB"
                     /locus_tag="PIB57_RS25515"
                     /old_locus_tag="PIB57_25520"
     CDS             12398..14260
                     /gene="taxB"
                     /locus_tag="PIB57_RS25515"
                     /old_locus_tag="PIB57_25520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxB"
                     /protein_id="WP_000847107.1"
                     /translation="MKTFNKSQSVFIFAVMLVAAWFAGSFIFFVLYFSQIKNLKPLKAV
                     FRSIDAYRMDIFTDSLTLSVVTTDIRVLAFVALGAGFVVSLIIPVAALIKLNEKKENIF
                     GDARFATINDIRESNSFTLDGDEKDGIIVGIKDKKIIRYVGAAFSAMGAGTRAGKGAGI
                     VITNLMKYWWSVIILDPKRECFNITSLIRKVILGHEVYKFDPFSPVTHRFNPLYYVSMG
                     TSEGFNQLENLSLIIYPYKTDGADAGSYLNKTAGGVFKSYAVALWFMIKNDKAGLKTLD
                     IEPVFSMSKINQLFERAEPEHLLSFMNDIRSELRGKDKTLADIGVAGLKAFIEMEDKTK
                     AQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNARLAEKITNIF
                     FQLGIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQV
                     GSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGSKSKSRSRGG
                     TSRSESENLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYLHEYFFGDFVKVA
                     PELANIFPRKKGKLVMPPQKVFENEIVAKGYLAVKDVPDLDKAA"
                     /name="taxB"
     gene            14269..14691
                     /locus_tag="PIB57_RS25520"
                     /old_locus_tag="PIB57_25525"
     CDS             14269..14691
                     /locus_tag="PIB57_RS25520"
                     /old_locus_tag="PIB57_25525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_001353737.1"
                     /translation="MMKKLVFLLISILAGCSSPPEPTPAQFEKANEVINPSLPYVPDFH
                     GVIKSEVSGKGWVYEITSLSGVQARTPTFYYALAHADRVVVTTHDAGLWFRIRDLLKME
                     GATAVVEWRNEKSFLPEQVKIVFIKAQNEVKNDWKK"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            14675..14980
                     /locus_tag="PIB57_RS25525"
                     /old_locus_tag="PIB57_25530"
     CDS             14675..14980
                     /locus_tag="PIB57_RS25525"
                     /old_locus_tag="PIB57_25530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_000147047.1"
                     /translation="MTGKNRVVLPVFLALGLISTNANASDPCASVLCLYGKAVGQGGGS
                     ECRSAEKDFFNILKKKKGSIRWSKTFDARKAFLNQCSTADPAAISKIMSKFGRVRG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            15035..15283
                     /locus_tag="PIB57_RS25530"
                     /old_locus_tag="PIB57_25535"
     CDS             15035..15283
                     /locus_tag="PIB57_RS25530"
                     /old_locus_tag="PIB57_25535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_159120708.1"
                     /translation="MNVTRFVTAPSDINKVKETHSDDELNRLLEAVNQNYPARIVLGSV
                     EKGKETPLKWCFRTIPERISIEEIDEIKFIKNPSEQR"
                     /name="hypothetical protein"
     gene            15355..15789
                     /locus_tag="PIB57_RS25535"
                     /old_locus_tag="PIB57_25540"
     CDS             15355..15789
                     /locus_tag="PIB57_RS25535"
                     /old_locus_tag="PIB57_25540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001576897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_201286317.1"
                     /translation="MMNKFSYVNRMLRRVFVFSFITAPSIALFVVFMFFSFNNSIAGSF
                     LKEARGLITDTPSDKVNVCLFEKGVPQDMELTNSTTEHVLKNKCITTLVDAADWQESVD
                     GSIRYFYWSSVIVGFAAWLTFNFSALEELFYRRNRKGDVE"
                     /name="hypothetical protein"
     gene            15786..16304
                     /locus_tag="PIB57_RS25540"
                     /old_locus_tag="PIB57_25545"
     CDS             15786..16304
                     /locus_tag="PIB57_RS25540"
                     /old_locus_tag="PIB57_25545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="WP_094326099.1"
                     /translation="MRILLSVILFLFTVFQSANAGGIPYTLNQEILQGKVIRVLDGDTI
                     EVKTLPAKIVVYEVPIRVRLINIDAPEKKQPFGRWSTNQLKTLLAGQSVTVSYTQTDRY
                     GRIIGRVFTTNGTDASRFMVQSGAAWVYERYNADESLPALQREAQEQKRGLWADSNPVP
                     PWEWRHKQN"
                     /name="thermonuclease family protein"
     gene            16386..17648
                     /locus_tag="PIB57_RS25545"
                     /old_locus_tag="PIB57_25550"
     CDS             16386..17648
                     /locus_tag="PIB57_RS25545"
                     /old_locus_tag="PIB57_25550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517490.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_001503550.1"
                     /translation="MGKLTLVEQALRLHKEYYGEDNFGTVVKDCDYYPKVAEIFINRKN
                     RKIYSNLDIEPVASTVVHTGSSPVMAKAGRIKKLMFKDGSGAYRIHLGQNEVVHIIRFI
                     LNSKVRMEYAVGTTKSMSMLHNLCEAGRAKLNRSLPRKGIWKLGYYDGVYYHGKARKEE
                     IENAMRFSVHPKFDELENDFNQFFSDIDFYTRYGQSGMRKVLFTGPPGTGKTTIAKALG
                     AKYQDKYVFVYADDYFKDVCYAAAQKKIPVIIIAEEVDELYRADAGTLSFLDGADTPRN
                     VAGTYVIFSTNYPKRIDPRIRKRPGRIDRIISVGAFRTKAAAACAKMYLPEDVEIDLKE
                     LGAVLDRTTPAEIKEIINIAIGMIRGTKNELSVDVIKNARAFLKGTLDLSVQEADEDIE
                     EREELYKKNGAQPDYLSYLED"
                     /name="AAA family ATPase"
     gene            17652..18227
                     /locus_tag="PIB57_RS25550"
                     /old_locus_tag="PIB57_25555"
     CDS             17652..18227
                     /locus_tag="PIB57_RS25550"
                     /old_locus_tag="PIB57_25555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001199074.1"
                     /translation="MQYALVDALERKFLLDALEFGVLKDWKENPVKELPDIDESVHPFH
                     VCYGGYLLNPGVSDSDISRKIKDQTGFWLAAIDDTRMDCHSIAYYDIHTLPLILCGHQK
                     IVPFAALIKADECIISKIASYSGFAVTAFLRIKDQDIATNILNREGIFAFNGCERRFRQ
                     PVSEDNWQQAVSEERAIRCANRLIQCKG"
                     /name="hypothetical protein"
     gene            18232..20385
                     /locus_tag="PIB57_RS25555"
                     /old_locus_tag="PIB57_25560"
     CDS             18232..20385
                     /locus_tag="PIB57_RS25555"
                     /old_locus_tag="PIB57_25560"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_053911937.1"
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPEYKAWKVETLPLRLYPVKYQPVESAAKQVKTILELIRRGDVTEIVHAGD
                     PDEEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKALARS
                     VADAVYGFSMTRAYTIPAIARGYKGVLSVGRVQTPILGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVIRANWKPGEFAPLTDRKLLDKAWANGTAASLAGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKLTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFPQSLDIDSSRKSKAFNSAKVTAHTAIIPTASVPDVNALSTDERNVYLAIAQ
                     HYLVQFMPEKAYQEVSVAIQCGDESFCARARKTTDSGFEAFLGAETTDEGESEDNDDSA
                     FELLCKIRTGETLTTKEVVVNEKKTTPPPLFTEASLLAALVRVADFVTDPTIKKLLKDK
                     DKDKKDEHGGIGTPATRAAILETLKKRNYITLEKGKLIPTDTGYALIDALPSIAVNPDM
                     TALWAEKQTAIENGDLTVEQFINELYGELADMITDVDLGDMKIEPAAPAGQSQRLESPC
                     PSCGKQIVIRPKGYFCTGCEFKIWNEFSGKKITQAQAEKLVKSGKTDLIKGFKKKSGGT
                     YDTVLVLEDKKTGKLGFPARVKK"
                     /name="type IA DNA topoisomerase"
     gene            20382..20588
                     /gene="hha"
                     /locus_tag="PIB57_RS25560"
                     /old_locus_tag="PIB57_25565"
     CDS             20382..20588
                     /gene="hha"
                     /locus_tag="PIB57_RS25560"
                     /old_locus_tag="PIB57_25565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_000850857.1"
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIDINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
                     /name="hha"
     gene            20604..21068
                     /locus_tag="PIB57_RS25565"
                     /old_locus_tag="PIB57_25570"
     CDS             20604..21068
                     /locus_tag="PIB57_RS25565"
                     /old_locus_tag="PIB57_25570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293133.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0030527 - structural constituent of chromatin [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_001293143.1"
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFSREIDFEQLLEMQEKLNVV
                     VEERREDAEREAAERQELEAKRQQAIEYIISLGLDPESLLAPVTADTVKTRRKAKGGVR
                     KAKYRFKDENGEIREWSGNGKRPLALQKLLDEGHFMEDFLIEKTKPEQAE"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            21689..22336
                     /locus_tag="PIB57_RS25570"
                     /old_locus_tag="PIB57_25575"
     CDS             21689..22336
                     /locus_tag="PIB57_RS25570"
                     /old_locus_tag="PIB57_25575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000587671.1"
                     /translation="MIIVIGGDKGGTGKSHLATNLTVCLSQQGKRTGLVETDLNGSTKK
                     WNKRREQAGLPPVALNEAYGDISAKITKMADVAEILIIDTAGYDSTEFRTALKVADIVI
                     VPIDPLAQVEADSLQTVTKIVRDAQKINPRLAAHVLLYKCQPNTFSEQQELRDSLNSHD
                     YWLKPMKSTVSFLRAFVRAMNQGMGVHELKSNVSGASQAKAQIELLLKELEL"
                     /name="division plane positioning ATPase MipZ"
     gene            22411..22680
                     /locus_tag="PIB57_RS25575"
                     /old_locus_tag="PIB57_25580"
     CDS             22411..22680
                     /locus_tag="PIB57_RS25575"
                     /old_locus_tag="PIB57_25580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001086090.1"
                     /translation="MAKLELPELEQNQEVNATKFVQDAGKRPTENKTKLASFRIPNELL
                     EFIDNESKRLHRPKTKIIKAALLAYQDLDENELINLWFRADRND"
                     /name="hypothetical protein"
     gene            22705..22920
                     /locus_tag="PIB57_RS25580"
                     /old_locus_tag="PIB57_25585"
     CDS             22705..22920
                     /locus_tag="PIB57_RS25580"
                     /old_locus_tag="PIB57_25585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000399458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000806548.1"
                     /translation="MKQCIFDLGIMNYDAVITWTVPVVFFFLVLLAGIAFNIGRKSNLI
                     VFALAMLLPVTTVFIFMLLGGKIDMC"
                     /name="hypothetical protein"
     gene            complement(23215..23742)
                     /locus_tag="PIB57_RS25585"
                     /old_locus_tag="PIB57_25590"
     CDS             complement(23215..23742)
                     /locus_tag="PIB57_RS25585"
                     /old_locus_tag="PIB57_25590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="WP_000577044.1"
                     /translation="MIFNRNKKRDEQHNSAVVLPSTENVFSDFIKNNPALITNAFTAIG
                     EVDCFTKVPLLSNKESEFLGILSRNIIPDYSVFPKIRLIEFVRPHGSEEAVKDLIREVQ
                     NITCDFVLKSYDETVLAVIQFGETATVRQQKKKLIIQRVCAMTGISFFEFKNTVDMMGS
                     EDFCQFLRDDEE"
                     /name="DUF2726 domain-containing protein"
     gene            complement(23878..24282)
                     /locus_tag="PIB57_RS25590"
                     /old_locus_tag="PIB57_25595"
     CDS             complement(23878..24282)
                     /locus_tag="PIB57_RS25590"
                     /old_locus_tag="PIB57_25595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_063270189.1"
                     /translation="MKDNVVDFQRIRRDLGAHSTDVANDAVYSDKKKISRFFYLLTPVR
                     YLLAASLYLVVVIPLGILAGFRFLLQFLGGIAVMGLTIAWYMGADVSGYVVLAAWIALT
                     VCGCAEQIFEWWIESRFAFRLFGIGRTPEE"
                     /name="hypothetical protein"
     gene            complement(24295..25164)
                     /locus_tag="PIB57_RS25595"
                     /old_locus_tag="PIB57_25600"
     CDS             complement(24295..25164)
                     /locus_tag="PIB57_RS25595"
                     /old_locus_tag="PIB57_25600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122745.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_271291424.1"
                     /translation="MMSSTGGMMMKLNIYMNLAQKTKIRHRNELNLTLAQLPLAAKRVM
                     YMALASVDSRKPIETGQVFRVRADDLASAADIEISVAYKQLKDGAKLLRGSSLTLTGDD
                     IIALSDELNLPYGSRNRPSEIDLSITDYCAYFNNEGYLELRFSRVIEPYISSLLGNKYK
                     FTTQLLTSCLRLSGQYSSALYQLIRKYHSKFSGKNSFIISLNELKEEIIAYTFKDDGTI
                     EYKYPDFPIFKRDVLNKAIAEIKKKTEVKELTCATYKKDGRKVSSLIFEFVIEENVFPE
                     EGMPESEN"
                     /name="replication initiation protein"
     gene            26862..27377
                     /locus_tag="PIB57_RS25600"
                     /old_locus_tag="PIB57_25605"
     CDS             26862..27377
                     /locus_tag="PIB57_RS25600"
                     /old_locus_tag="PIB57_25605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025395.1"
                     /translation="MNIQEALNVFGLSGELTEKDIKAAYRKAALKYHPDRNPLGAELMK
                     AVNAAFDVLMANIDKINQFQSTDEHARYNYGDDLEKVLNVLSGLSGLVFEVIGNWVWIS
                     GETITHKETLKEIGCKWAAKKKQWFYRPDEHKSYWNREEHTIEEIRAKYGTTGQRRATG
                     WQRVETRA"
                     /name="J domain-containing protein"
     gene            27482..28024
                     /locus_tag="PIB57_RS25605"
                     /old_locus_tag="PIB57_25610"
     CDS             27482..28024
                     /locus_tag="PIB57_RS25605"
                     /old_locus_tag="PIB57_25610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001083906.1"
                     /translation="MNSFFEQYHPVFEVVCRILGNGWRVNKLDDCSSRIKLTSPQFKNY
                     SVHIRMEKDRFSVVGSVDSRSWRSPHHVCTLSRKRNPVDIAADIERKILVNASQEVLQA
                     IEYEKHQVEKKDEILILKGMLSQLVQLESWYGALTGFKAENGLNGKVTEQGDSYDLQIR
                     GLSIDQLVKITGYLKQL"
                     /name="hypothetical protein"
     gene            28021..28272
                     /locus_tag="PIB57_RS25610"
                     /old_locus_tag="PIB57_25615"
     CDS             28021..28272
                     /locus_tag="PIB57_RS25610"
                     /old_locus_tag="PIB57_25615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001565860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001230707.1"
                     /translation="MRKNKGDVTYFLEKEGDNYRLTKRIKARTNVKIGNKTTKITLYDA
                     VLNENELQHIDFTCAGLREDDETPVKNLIKEFMLNETR"
                     /name="hypothetical protein"
     gene            28259..28486
                     /locus_tag="PIB57_RS25615"
                     /old_locus_tag="PIB57_25620"
     CDS             28259..28486
                     /locus_tag="PIB57_RS25615"
                     /old_locus_tag="PIB57_25620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000801440.1"
                     /translation="MKPDNTPENVKKLRLKAGLTQKECSHIYGVGLRTWQKKEEVNTQN
                     SQSLSLVEFEFLLLLAGEHPEYVLCKRESK"
                     /name="hypothetical protein"
     gene            28488..28808
                     /locus_tag="PIB57_RS25620"
                     /old_locus_tag="PIB57_25625"
     CDS             28488..28808
                     /locus_tag="PIB57_RS25620"
                     /old_locus_tag="PIB57_25625"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="WP_224693477.1"
                     /translation="MTCDGFILVPGVAPVARWRSHAQYSAPSRETLDGVNSLARALTAA
                     FCGANQHNHGLLVSWALQGEGMACAPWYVRQRLRRASGRCGSCAALVFSFAPSIRLRGL
                     KT"
                     /name="molecular chaperone DnaJ"
     gene            28935..29207
                     /locus_tag="PIB57_RS25625"
                     /old_locus_tag="PIB57_25630"
     CDS             28935..29207
                     /locus_tag="PIB57_RS25625"
                     /old_locus_tag="PIB57_25630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001272119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001272373.1"
                     /translation="MSAFVFRTTFKPTGDQQKDAIAHIEVMQERAVKAFVSWMSCQECS
                     DFLSNLQEITTELNSLIDAVESHTPVFRKKADELEALLAHYKTLL"
                     /name="hypothetical protein"
     gene            29275..29580
                     /locus_tag="PIB57_RS25630"
                     /old_locus_tag="PIB57_25635"
     CDS             29275..29580
                     /locus_tag="PIB57_RS25630"
                     /old_locus_tag="PIB57_25635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_072182957.1"
                     /translation="MARLPFIESTTQQIFVFNTLTLCTIGLIHLETEKEYVVVFTDNNK
                     IRDYKTGIVTQFGELKQSDIDLILFYRDEYEKYFDSLNNGEEYLSFKEYIGCIRGE"
                     /name="hypothetical protein"
     gene            29886..30134
                     /locus_tag="PIB57_RS25635"
                     /old_locus_tag="PIB57_25640"
     CDS             29886..30134
                     /locus_tag="PIB57_RS25635"
                     /old_locus_tag="PIB57_25640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005653200.1"
                     /GO_function="GO:0003729 - mRNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family toxin"
                     /protein_id="WP_000520549.1"
                     /translation="MGKTDKLLAKFLNSKKTFEWDELVVLFSSLGYVKKEMQGSRVRFF
                     NAEINHTILMHRPHPESYIKGGTLKAIKQNLKEAGLL"
                     /name="type II toxin-antitoxin system HicA family toxin"
     gene            30131..30478
                     /locus_tag="PIB57_RS25640"
                     /old_locus_tag="PIB57_25645"
     CDS             30131..30478
                     /locus_tag="PIB57_RS25640"
                     /old_locus_tag="PIB57_25645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="WP_000681613.1"
                     /translation="MKHLKYKGYLGTVEPDFENNVLYGKLAFIRDLVTYEASTLAELEQ
                     EFKTSVDLYLQSCVEDGKEPDTPFKGVFNVRLDPELHRRVAEMAMEEDLSLNAFVNKAL
                     EKEVSNHRAGA"
                     /name="type II toxin-antitoxin system HicB family
                     antitoxin"
     Typing          456..1681
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.132"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          7089..8164
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.164"
                     /coverage="100.0"
                     /evalue="9.03e-173"
     Typing          8680..9362
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.123"
                     /coverage="100.0"
                     /evalue="1.68e-137"
     Typing          9363..10267
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.338"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          12399..14257
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.871"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ctattttaag tggatttacc agtgtcaatg cttttgctaa gcataatgtg cttaatattg
       61 aaaccaagcc tgttaatatt ccagttaata atgaagcagc aaagctggta tcagtgcgcc
      121 tttaccctca tgaaatagaa cttgttaaac gtaatgctgt ccttcacggc atgagcatga
      181 gcagagaaat tgctattcgt gtacgtcagt ctttgttaaa aaatgaagtc tgtctttatc
      241 ctgatgagat taaagaaatc aggagactta aaacggaaat taacaaactc ggacgcaatg
      301 ttcattatat cattagtggt gacagatttt gtattgttaa cgatcctgaa ttcagaaagg
      361 aaattaatga tgcgcttaat atttgtcagc aaacagcgaa acagttagaa actctggtga
      421 ctgctgtagt gaacagattt tgataaggtg agttatgggt gtgcatgtag aacaggaata
      481 ccgtattaaa cgtgctaaaa gtactgggcg tgatccgaaa attccgaaac tgtctggaag
      541 gcatctacat gccagtaaat cagcctttaa tcataaagtc aggcatggag cagacaagaa
      601 ggcatacaac tggacaccta caaaagaagt cacttttaaa atcactggct cgggtaaaac
      661 tcccgcaggg atcaaaaatg gcattgacta cattacccgt aatggtgaac ttgaggctta
      721 ctactatgat ggcgatggcc gtgaaaaaac tggatgtggg cgaaatttta acgctggtat
      781 tacatcaggt atgacagagg ataatgatta ttctaaaaca tatcgtggag aaaacatcga
      841 tcatgtgaaa aacatggtct tttcaccacc accagaagct ggagtaagca gggaagacgc
      901 tctgaaagct acggtagaat ttcttaaaga gacttatcca aaccatgctt tcgttgccgt
      961 ataccatgat gataaagaag atcatcctca tgtacatgtt aatattaaac ttcgtgatga
     1021 agaaacagga agaagattaa gacttactaa atctgaaacc aggaagttca gaaacggttt
     1081 tcatagaaaa ctgaaaggta tgggatatga tgttaccgct acctggaaaa aagatcccga
     1141 acgtaaacgg gagattgagc gattacaggc tgaaaatccg aaaagactcc ggaatgttta
     1201 caaggtggtg gattttgggg agacttcata tcagaataag gcaggggaaa aacgaacacc
     1261 tttcctcact tatgaaactt taaaaggtgg aaaacaggtt acgatttggg gtaaagacct
     1321 gaaaaatcat ttcgagtctg aaaagctcca gccaggaacg cttatcaaag taaaaaaact
     1381 ggctcctacg cttgtacgta gtccaatgtt taatgatgat ggaactgttg caggctacag
     1441 ggaaacgcat cgcaataact ggcagattga aaatattgcc cttgagcgga acagagaacg
     1501 tcaggttcat gagcgtgaaa ccaggcagcc ggaagagagc gacgttaaaa agcagctatc
     1561 cagaaaacat gagcaaggtc acaatatcgg gtttgctctt gaacacgggt ttacaaagga
     1621 ttcagaagaa cataaaaaac taagaataca gcaagagagg aactggaaag gcctgggatt
     1681 ttaatttgat ttcggcgcag gtgaacaaag cggctacttt gctcacctgc taatcacaac
     1741 aacctacgag ggaggttatc atgactgagc atgatgctat ctgcatttct gcacttcatc
     1801 aaatttttag tgatgaagaa catttgagtg agcaacaaaa agacattatt ctgatgtacg
     1861 cttatggcta taccctgaat gaaattgctg atttcaaagg actaaagcct tcaactgtca
     1921 gaaaatatct cgattctgta agagctgaac tgggaggtgt ctcgttggca gggatcagaa
     1981 cactggtact cattcggact aatgcccttc tcgtgtcaag tctttccagg atcagtgaga
     2041 gggggaattt atgaaaaaat atctgctttt tgctttgccg ttcttcgttg ttggttgtag
     2101 tgaagaagta aaaagtgtgg attggtgggg gcagcatctt acggaagcta aacaaaagca
     2161 ggcagagtgt gagaagtctg gctctgattc tcagaactgt aagaatgtta aacaagcatt
     2221 gtttattcag tctcagaagg atgctccagt ccctacattc gattaactaa tgtttaaatc
     2281 atactaaagc gcccatatgg gcgctttttt ttgcatgatc acacgaatca taatatgacc
     2341 attttgtcaa tgttatttga tcgtattgtt gagcattgtt attttgcgaa tcatgttcgc
     2401 atctaaaaca aatccaaaac acacttatag tggattgatt aaatgaagga gaaatcagat
     2461 aagtcatcgg aaaaaggggt ttatgtcacg ataaaactcg atcccaggtt gaatgcattt
     2521 atcgaagaga aaacgaaaac atctttgctt agtaagagga agcaaattat ttacttatta
     2581 atgcagagta tgcgtattga tggatatatg gagcgttagc tatggcgtct ttattcccag
     2641 ccttgttgct gtgtgcggcg tcagttcatc cggatacgat aaatgatatt gcacgggtcg
     2701 agagtggctt caatccttat gctgtggctg aaattattcc tgaaagggaa cgcggtagct
     2761 atggcaaaag tgttatcagt catatgccca aaagtaagga ggaagctcta acagttatca
     2821 gagaaattga aaacagaaaa agacgttatt ctgtcggatt gatgcagatt accagcagta
     2881 atttttcttt ttattccacg tccgcagaaa aactccttga ttcgtgtgaa aacttgtctg
     2941 ttttcgaaaa gattatcgtg gattgttata aacgagggag gagcctggag aatgcgctta
     3001 gttgttacta tacaggaaat tttagtaacg gtaagcgaaa agaaaaagaa tttaataata
     3061 caagttatgt tgagcgaatt ggttatacag ggaacgaaaa aaaatatgtt gtaccaggta
     3121 caagaagcaa cgggggagaa cagcgaaaaa atcgttcaca caatgcgtca gttatctggc
     3181 ccgaaaccat tctgaaatct gcttttgttg ataactcaca tccaacaaaa gttattaatt
     3241 aacaggactt ataaaatgtc atttaagaaa tcagtatgta atcgtatcag ttcatctgtc
     3301 actgctgtaa tgcagcgtaa aaataaggta gttatggcag tcgccggggc aacagttgca
     3361 tcaccggcct ttgcggatgg attttcaaaa gcggaaacac tgctggaaaa ggttaaaaca
     3421 gggcttagtg gcctttcact ggtcacggtg actattgcct gtctgtgggt cggctacaag
     3481 gttctgtttg gtggaagcac gattcgtgaa tgctcaccta tcatcatcgg ggcaattgtt
     3541 atcgccagtg cggctgaagt tgcatcaatg atggttaact aataaagcgg ggacgatagt
     3601 atgtctacac tttataaagc gatgacacgc cctgctatgt atgtgggtgt tcctgtcgtc
     3661 cctcttactg tggttgcagg ggcgttattt ctggcggggg tttatatcag caagctgatc
     3721 tggctggcta ttcctgtcgc ggtttttgtt ctcagaatga tcactaaaca ggacgaccac
     3781 atttttaacc tttactttct taagctgaaa atgctcggaa actcagtgtg taatcgtttt
     3841 tttggcgcac gagcgttcct ctccggacaa tatgaagctg ttgaaattga tgagtttgtt
     3901 aatgccatga aactgaatga gcgaatcact actggtaaat atatcccata ttcaagccac
     3961 gttgataaaa acatcgtcaa aacaaaaaac ggtgattatg tagcgacatg gcaactgatg
     4021 gggattaact ttgagtcaat ctctgcggag atgttagaaa ctattgactc acaggttgcc
     4081 actcttgttc gttcattttc cggactgccc gtttcatttt ataaccattc atgcagggcg
     4141 agtttttatg atgcctttac cacaaaatca ggtaataaat atgctgatat aatatcagac
     4201 tgttattatg gttcgatgaa gaaaaataaa ttcaagggga acactcttta ctttacgctg
     4261 atctacagac cagacgggcg tgtagaaaaa ctggaaaaac gcaaaaaaag tattaaagaa
     4321 aagaaagatg atattaacat tcatgtgaag agaatgaatg aaatgattaa tacattctct
     4381 ggcgctcttg ataaatttac ttgtaaactt cttggtatgt atgaggagaa cggaaaggta
     4441 ttttcttctc aactgtcatt ctataattat cttctgacag ggaagttgca aaaaatcaga
     4501 gtcactgatt ctccggtgta taacgttctt ggtggagtgg atgtattttt taatcatgat
     4561 accggacaga tatgccgcat tgatggaaat aaattctttc gttctattga aattaaagat
     4621 ttctgtagtg agactgcatc cggtgttttt gatgtgctcc agtattctga tgctgactat
     4681 attattacgc attcatatac atccatgagc aaatcagaag cattgagtac cattaaacgt
     4741 gcggaaaaac agttaaagag tacagaagat gatgcggtta ctcaattgca ggaactggaa
     4801 aaggcaaaaa atgatattgt gtccggtgat atatcctttg gttactacca tttcacgcta
     4861 atggtaatgg cggacagtat cagggagctt gacgaatctg taagtaaaat tacggcagac
     4921 tttactgacc tgggcattat tccggcattg tcaaccatgt cattgccagc agcatatttt
     4981 gcccagcttc cggcggtttt tcatttaaga ccgcgtttat ctccggtatc gaatgtaaat
     5041 tttgtcgaac tggcatcatt ccataatttc taccagggga aacgcgataa aaactgctgg
     5101 acagaagcgg ttgctattct caaaacacca agcaaacagg cgtattatct gaatttacat
     5161 aactcagtac tgtttaaaga tgaaacaggt gaaaagaatc ttgctaatac taaagttata
     5221 ggaacggcgg gttcaggtaa gacaatgttt ctgtcatatc ttgcctgttc attacagaaa
     5281 tacaataacc ctgaaacttt tgctgattct gcaaaaaata agaagttaac gtgtgtcttt
     5341 cttgataagg acagaggggc tgaattatgt atcagaatgc ttggtgggga atattacacc
     5401 gtaaaaagcg gtgagccgac aggatggaat ccttttgctc tggaggcaac aaaacgtaac
     5461 cgtatttttg tcaagcaact gatggagatt ctgtgtacca gaaatggtga aagattatcg
     5521 acaagagaaa gattgcttat tagcgaaagt gttgatgctg tgatggattt tcctcctggc
     5581 gaaatgcggg aatatggtat tacccgaatg cttgagcatc ttatgcagag agatgatcgg
     5641 gatgagcagg agaacgggat tatccttcgg ttgtcccaat gggctaatgg tcaggctcat
     5701 ggctgggttt ttgataatgc taaagacaca ttcaatattc agcatgtcaa taattttggc
     5761 attgatggca ccgagtttct tgatgatccg atggtatgtg caccaattac tttctatctg
     5821 ctgtatcgca ttacgcagct tcttgacggt cggcgtcttg ttatcttcct ggatgagttc
     5881 tggaaatggc tacaggatga agcattcagc gactttgtct ataacaagct gaaaacaatt
     5941 cgtaagctga acgggctggt tattccggca actcagtctc cggatgaaat actgaagaat
     6001 aagatttcac gggctgtggt tgaagtatgc agcaccagta tttatctggc taaccctgat
     6061 gccgattaca atgattatgt ggaagggctt aagctgacac cagaagaatt taatattgtt
     6121 aaaaatcttg atccaatgtc gagacagttc ctgattaaaa aaagcagtct taaaaaaggg
     6181 gatggtaaat cattttcagc acttgcgaca ctcgatttat cgggacttgg tggatatctg
     6241 aaaatattgt ctgccagtgc agataatctg gaaatttttg aaagtattta tcatgaagga
     6301 atggagcctg atgactgggt tcctgaatat ctcgaacggg caatctgaca ggtgaattta
     6361 tgaaacgtgt aaaaacattg atgctgatat cattattgac ggcttcattt tatagtagcg
     6421 caggaattcc ggttgctatt gatgccagtc cggaatgggc tgttgaagcc gcaagatgga
     6481 cagaacgact caaacaatgg tccgaaactg cgcaacatta tcagagtcag attcaggcat
     6541 ataaagacca gttagccacg gcaacaggta taaggaatat tgcggcattc acaaatgaac
     6601 taagtaatct acaatcagaa ctgacaaata tttataagca ggggaacagt tatatttctg
     6661 attttaccag taatcccgaa ggtgcattga gcagccaggc taaaaatctg ttcagcaagt
     6721 atggagcctt cgatatgtgt aatacgggct atgaacgtaa tgataatctc tgtaaagcac
     6781 ggattgtgtc aacggctgcc agtattgaac agggaaatga gatcaataag cagttatcaa
     6841 gtgcaatgtc tcagattcag agtttaagta gccgaattga ggcttcaaag gatatcaaag
     6901 aatcccagga tttggctaac gcattacagg cgcagtcgtt aaaaatgcag gcgataaaaa
     6961 tgcagtatga tgtctggaat aataaaaata aagcagatca tgagatgttg gtcacacaag
     7021 aacaagaggc ctttattaaa cagcagaaag aagctgaacc attaactttt gattaaaagg
     7081 tggatatatg gctcaggggt ttttcgttaa atataattct accgttatgg attcggtaga
     7141 taaaatcagc tccagttatc aaacacaatt tgctaatgat attatgtcgt tagcgacggt
     7201 atcggttacg ttatatgtac tatggaaagg atatcaaata cttgccagta aaactcagac
     7261 gcccttgcag gatttagtat gggatctatc aaaatttgca atcataatca tgtttataac
     7321 taatgcggat gggtatttaa ctgcggctac tgatgcgttg caaggcatga aagatggttt
     7381 ttctggaggg gtgagtgtct ggcaaacttt agataactta tggaaaagta cgcaaaatct
     7441 tggtgcggaa atatactctt tagataaatc aacatatgtt aaagatcaag gtgtagttgg
     7501 tcagttttta atatggactg gctcgcttat tttaatggct gttagtgtgg ttgttttttt
     7561 aacagcagat gtaacgatga aactcctgat tattacagca ccgatattta tcttttgtct
     7621 catgtttggt tttattcgga gcatgtttaa taattggtta caatcgttat tctccagtat
     7681 tctgacagtt ctatttgcca gtttagtgat tcggatagca atggattttc aagggatgat
     7741 cctttcccat gctattcgtg ctgcacaaac agggaatgta aatcttgtat ctacaggtgc
     7801 tatgggcttt atggctgggt ttttgggggc tttattggtt cttatagcta aaggttttgc
     7861 tgtccagtta gcaggtgcag gtgttgaagg tgctgttcag ggcgcagcca tgatggggct
     7921 gggtgctgct ggtatggcta ctggtaagtc tctgatgctt ggcggtcgtg ctggtttagg
     7981 ttttggctta gggatggccg gaagaacggg catgaattct ttatcaggga aagcagggaa
     8041 tctgatgggg cgtggtgcgc gaacagccgc tgaatgggcg ggtgaaaagg gatatcaggc
     8101 gctggctccg acaggtgctt tggggatgaa ggctagaaga cttgcatccc tggaaaaagc
     8161 gcgagcgagg aatgccgcat gaatatcatg aaacgttttt tttatgtgat gtccctgaac
     8221 tggatactga cgtttgttga taaacatatc acctccggat ggagcaggaa gagaaagcta
     8281 ataacccagc ttgttatttt aatcacggga attaccttat ttaaggtctt aggtggaatc
     8341 agtcagagct ggttgtgaca tgcttcatta ttttgtccta atccttcttt taggagtgtt
     8401 tacctgcttc gcaggaataa ggcttggttt agggcttgcg ggaaaatgga gaaagagtat
     8461 ggatcttcgc tttttgattc ttattggtgg gattcttttt cttcatcttg gcctttatct
     8521 cttaaaggtg ttcgtgaacg cttaataagg tgaatttatg cgatatgtga tttttttgtt
     8581 tttcctgttt cagatttccg gatgtaccac aaggaatacc cttccttctg atgtttccgg
     8641 cgaactggaa cccattaacc acagccaggt aatcagttat gagtgaaaaa atcgaaaaga
     8701 agattgagac agctaaatcc ttcgaaagac aactctatgc agaaaatgaa cggtctaaga
     8761 aaaatgcatg gcgtgttgca gcggcagcat cattactgtc cttatgtctt ggggctgcaa
     8821 tttgtgttct tgtgccatta aaagaaaaag agcttgctat tgtggctgtt ggcgaaaaaa
     8881 caggccgtac agaactgatt actcaggtta aacaggaaaa gattctgcaa tctgaagcac
     8941 ttgggcggta ttttgtaaac acgtatatta ctttacgtga aggttataat tatccgtctc
     9001 ttcagtatga ttatgagact gtacagctat atagctcgaa tacagtaaag gacgattatc
     9061 ttcgtttgta taacagcgat atggctcctg ataaaattta tcataataac ggttcttacg
     9121 ttgcgattga ggtcatctcc aatattattt ctgacgcaac cgcgccagat aaactggcct
     9181 ctgtgcgctt taaaaaaacg acgagaaact tcacgaccgg acaggtttca gtttcatact
     9241 ggacggctcg tgtgacatat cgttttgaac cagaaaagtc ggttaaaagt tccagtcgtg
     9301 agcttaatcc tctcggtttt actgtaacca gttaccagac agatcgggaa gtcagggggg
     9361 aatgatgaag aaattattta ttgctacatg tttattgctt cctgggcttg tgtattcagc
     9421 agcgactccg ttaccttctg gatttgatgc aaggatgcag actgtgagtt ataacggtgc
     9481 gaatacgacc gttatccggt caaagacagg atttctcaca tcagttgttt ttgatgaagg
     9541 tgaggctgtt atcagtgcaa aggctggttt tcctgccgga tgggaaatca caaccgatga
     9601 taatgttgtt tacatcaatc cgcgtccagt tgttcaggaa caggaaggcg atgaaggcga
     9661 aaaactgaaa aaggttttcc agccaacaga aaaggaatgg gatacgaatc tttttgtcag
     9721 aacaacaaag cggatttaca gtctggatct aatccttctg tcagaagaaa aacaagcgca
     9781 acctgcttat gttgtacaat tccgctatcc atcagaaata gcgaaaaaga atgcagaaga
     9841 agtaaggctg gcaaaagaaa aacaggaaaa actcagacag aagaaactga tttctgaaag
     9901 ttttgaaaaa gccgatgcgc ctaaaaactg gaattatttc atgcgagtca atgaaaaata
     9961 tgacagccgt cgtatcgccc ctgattttgc ttatgataat ggcatattta cctttttagg
    10021 ttttaactca gggaaagtat tcccagctcc atttgctgta agagatgatc aggaacagac
    10081 acttgctttt aatgtggaaa caaaaggcaa gtataaaatt atggttatcc acaacgttaa
    10141 tgacaaattt gttttacgct atggaaacag cgttgttggt gttgtgaata aatctttcgg
    10201 aaaagtacta accgaccaga ggaatacatc ttctcctgcg gtagaacgtg ttgaggtgaa
    10261 taatgactga tatgaaaaaa acagatgatt tagttgatga tgcgaatcag tcaaagctgg
    10321 aaagtaaacc cgttcatgat atcggtgata tcaggaacaa aaataatcgt atgcgttctg
    10381 gctttctgtt tggtctgatg gctgtattag ttattggtat ttttgcgctg aaaacatata
    10441 aaaattattt tgcagatgac cagcagaaag catcagaatc aacaggcgat accagcattt
    10501 ctcaggtaag taaaatccgt actggtcttg gtcagaattt tgaccctgtt gagaacaaag
    10561 caattattaa tcctggtgct actggctctg gtaatactgt ttctgacggt cataaagaag
    10621 taccacagga ggggttcagg aaatatttgt caatacctgt tgctgatcag ggagggagtc
    10681 agactggcgc gagtggcagc agcaggacat cgcagacatc agagccacag gaagaaagga
    10741 aagaatcaaa agaaaatgtt cctggtaaat caggaatgaa agtgactgct attaagctca
    10801 atcctgatct ctatattgag gaaaacaggc ttataccgtg tgctttaacc acacgctttg
    10861 tttctgatgt tgctggtcgt atcagttgtg tttttacaga agatgtatgg agtgctaatc
    10921 accacacaaa attactggaa cagggaacta aggcttttgg tcgttaccag accggaacgc
    10981 tgaatcatgg acagggcaga atgttcgtta tgtgggagca gttgcggacg cctgataata
    11041 aacgaatcga tatggtaaat acagcagcgg ctggccccct gggagaagcg ggcattgatg
    11101 gatggatcga ttctcacttc tgggagcgtt ttggtggttc tcttatgctc agtatggttc
    11161 aggatgtagc ggctgcggcg gcggataatg cacctggtaa agatcgtaat gtggattata
    11221 ccgaaaactc acgacaggca atggctgaaa tggctaaagt cgcacttgag aattcgataa
    11281 atattcctcc aacaatgtat aaaaaccagg gtgacataat cactattatg gtcggggaag
    11341 acattgattt ttctgatatc tatgagttaa aggtaaaata gtatgaatgg cgttattcct
    11401 gtcagcatta gcaataaatc gctcgatttt tataaaaatc aagtattcca gtcttttctt
    11461 gatattgaag ggctaacaga aattgctgtc aaccgtcctg gtgaaatctg gacggaaatt
    11521 aatggtgact ggacattcca taataatgac agtgtgacct ttgatttttg taaacgtttt
    11581 tctcagacgc tggcatcatt tcggggagat gaaatcggcg ataccaagcc attactttca
    11641 gcaacactgg aatcaggaga acgtgtacag gtcgtttttc ctcctgcatg tgagagaaat
    11701 actatttcaa tcaccatacg taaaccatcg acacggcaga taacgcataa agaatatgtg
    11761 gcgaacggtt tttatgatta tgtccagtca ggaaaaaaac acaggacata cgatgatgag
    11821 cttcttgatt tattcagagc gagaaatatc gctgctttta tggagcttgc cgtagcagca
    11881 gggaaaacca ttgtatttgc cggagcaacg ggttccggta aaacaacata tatgaagagt
    11941 cttatcgatt tcataccatt gaatacacgg ctgattacga ttgaagatgc agaggaaatc
    12001 aaatttttta tccataaaaa ttatgtgcat cttttttacc cttcggaatc cggcagtgat
    12061 tccggctcta tcataacagc agcgaaatta atcaaatcct gtttgagaat gaaacctgac
    12121 agaattttac tggcggaaat taaaggtggc gatgcctggg attttgtgaa agttgctggt
    12181 tctggtcaca gtggaagcat gacgtccatt cacgcggcct cggcaaaaga tgccatcatt
    12241 cagatggtga caaaatgtta tcagaacaga gaatgtcaga atcttccttt tgatgttctt
    12301 cgtaaaatca ttatggacag tattgatatt gttgttcatg taggcaggga tggtgttgtc
    12361 aggcatatga gcgacatcta ttacaaaggg gctgaatgtg aaaactttta ataagtcgca
    12421 atctgttttt atattcgctg ttatgcttgt tgcggcatgg tttgcaggtt catttatttt
    12481 ctttgtgctt tacttcagcc agataaagaa tctgaaacca ttgaaggctg tgttcagatc
    12541 cattgatgcg tacaggatgg atatttttac agacagcctt actttatctg ttgtgactac
    12601 ggatatcaga gttttagcct ttgttgcact tggagcagga tttgtcgtgt ctcttatcat
    12661 ccctgttgcg gcgttgataa aactgaacga gaagaaagaa aatattttcg gtgatgcgcg
    12721 atttgcaaca attaatgata ttcgtgagtc taacagtttc acgcttgacg gtgacgaaaa
    12781 agacgggatt atcgttggta taaaagacaa gaaaataata cgctatgtgg gagcagcatt
    12841 cagtgctatg ggagccggaa caagggctgg taaaggtgct ggtatagtca tcactaatct
    12901 tatgaagtac tggtggagtg ttattattct cgatccaaaa agggagtgtt ttaatatcac
    12961 cagtcttatc aggaaggtga ttttaggtca tgaggtttat aaatttgatc cctttagtcc
    13021 ggtaacgcac cgctttaacc ctttgtatta tgtcagcatg ggaacgagtg aaggttttaa
    13081 ccagcttgaa aatctttcgt tgattattta cccctataag acagatggtg cggatgctgg
    13141 tagctatctt aataagacgg cgggtggtgt ttttaaatct tatgctgtcg ctttatggtt
    13201 tatgattaag aatgataagg ctggactaaa aacgcttgat attgagcctg tcttctcaat
    13261 gtctaaaatt aatcagcttt ttgagcgtgc agaacccgaa catcttcttt cattcatgaa
    13321 tgatattcgt tcagaattaa gggggaaaga caaaacgctt gctgatattg gtgtcgctgg
    13381 ccttaaggca ttcattgaga tggaggataa aacaaaagca caactcaaaa gcaactttct
    13441 taatggatta tcaccgtttg ctaaccccaa tgtggcgaat gctactgatg gaaatgattt
    13501 tgatttgcgg caggtgcgga aaaaacggat gacaatttat ttctgtattt ctggtgataa
    13561 tgccaggttg gctgaaaaaa taacaaatat tttctttcag cttggtatac aggtgaatct
    13621 tgaaaagatg ccaacggatg atccggaaat aaagcatgac tgcctttttc tactggatga
    13681 attcccgtca attggtgctg tagattacat caagagtaaa tctggtctta ttgctggtta
    13741 caagctgaaa ttgttgattg tttaccaggt cggctctcag cttgaggaaa tctacagtta
    13801 tgcaggcagt aaaacattac tggcaagtgc accctgcaaa atcgtttatt ctgcttctga
    13861 tgttaaagat gcacgggagt tatcagaggc gatgggaaca cgaacagtaa ctatcggttc
    13921 gaaaagcaaa agtcgtagtc gtggaggaac atcgagatct gaatcagaaa accttattga
    13981 gcgtccactg gtaacaacaa atgaactact gacactgaaa tttagtgaag aaatcctggc
    14041 aatgaaggga gaaaacccga ttcgttgtga aaaggcattc tactatctcc atgagtattt
    14101 ctttggtgat tttgtgaagg ttgctccgga acttgcaaat attttcccca ggaagaaagg
    14161 aaagctggtt atgcctccac agaaagtatt tgaaaatgaa atcgtcgcaa aagggtatct
    14221 ggcagtaaaa gatgttcctg atctcgataa agcggcataa aggagaacat gatgaagaag
    14281 ttagtgtttt tattgatttc tatccttgct ggttgttcat caccgccaga gccaacaccc
    14341 gcgcagtttg aaaaggcaaa tgaagtgatc aatccctcat tgccgtatgt ccccgatttt
    14401 cacggcgtca taaagtcaga agttagcggt aaaggatggg tttatgagat cacttcctta
    14461 tccggtgtac aggccagaac gccgacgttc tattacgctc tggctcatgc ggacagggtg
    14521 gtagtgacaa cacatgatgc tgggctgtgg tttcgaatca gagatctgtt gaagatggaa
    14581 ggggcaacag cagtcgtgga atggcgaaac gagaaaagtt ttttacctga acaggtaaaa
    14641 atagttttca ttaaagcaca aaatgaggtg aaaaatgact ggaaaaaata gagtggtttt
    14701 acctgtcttt ctggcgttag gattaatatc aacaaatgct aatgcatctg acccttgcgc
    14761 ttcggtactt tgcttatatg gaaaagcagt cgggcaaggt ggagggagtg aatgcagaag
    14821 tgctgaaaag gattttttta atattctgaa aaagaaaaaa ggaagcattc gctggagtaa
    14881 aacttttgat gcccgtaaag catttctgaa tcagtgttca acggctgatc ctgctgctat
    14941 atcgaaaatc atgagtaagt ttggtcgtgt cagaggttaa ttaaaacctg atacccgcgc
    15001 caacgggtat caagggatat acaggacaat aattatgaat gtaactagat ttgtaaccgc
    15061 accatctgat attaacaagg ttaaagagac tcattctgat gacgagttaa accgtttgct
    15121 ggaagctgtt aatcagaatt acccagccag aattgtgttg ggtagtgtgg agaaggggaa
    15181 agaaacacca ctcaagtggt gttttagaac aataccagag cgtatttcaa ttgaagaaat
    15241 tgatgaaata aaatttatca agaatccttc tgaacagaga taaaggtaaa cgccgcagat
    15301 tccagatttt aatctgggat ttgcggggtt gaacaaccga agggcgttag ttttatgatg
    15361 aataaattta gttatgtcaa tcgtatgctt cggcgcgttt ttgtttttag ttttatcacg
    15421 gccccatcaa tagctttatt tgttgttttt atgttttttt cgtttaataa ctcaattgct
    15481 ggttcatttt taaaagaggc cagggggctt ataaccgata ctccttctga taaggttaac
    15541 gtctgtcttt tcgaaaaggg cgtaccacag gatatggagt tgacaaactc cacaactgaa
    15601 catgtattaa aaaataaatg tataacaacg ttagttgatg ctgctgactg gcaggaatct
    15661 gttgacggtt ccattcgata tttttattgg tcatcagtta ttgtgggctt tgcggcctgg
    15721 cttaccttta atttttctgc gctggaagaa ttattttatc gtagaaacag aaaaggagac
    15781 gttgaatgag aattttgtta agcgttattt tattcctgtt tactgttttt cagtctgcaa
    15841 atgcaggtgg aataccttat acattaaatc aggaaattct tcaggggaaa gttattcgcg
    15901 ttctcgatgg cgacaccata gaagttaaaa cgctacccgc gaaaattgtt gtgtatgaag
    15961 ttccgattcg ggtccgattg ataaatatcg atgcccctga aaagaaacaa ccttttggac
    16021 gctggtcaac aaatcaactt aaaaccctgc tcgcaggcca atccgttacc gtctcttata
    16081 cgcaaacaga ccgctacgga cgcattatcg gtcgtgtgtt cacgacgaac ggcacagatg
    16141 ccagccgctt tatggttcag tctggtgctg catgggtata tgaacgttac aacgcggatg
    16201 agtcattacc ggctctgcaa cgggaagcgc aggaacaaaa acgaggttta tgggctgaca
    16261 gtaatccggt tccaccgtgg gaatggcgac ataaacagaa ctgacgcgcg ttgcttgtcc
    16321 aacccctcca ctaccttaaa taaatttcag gcagtgtcac ggttttaaat atacatggtg
    16381 cgcttatggg taaattaact ctggtagagc aggctttacg tcttcacaaa gaatattacg
    16441 gtgaagataa ttttggtact gtcgtaaagg attgtgatta ctatcctaaa gtggcagaga
    16501 tttttataaa cagaaagaat cgtaaaattt attcgaatct ggatatcgaa cctgttgctt
    16561 caaccgttgt tcatacggga agtagccctg ttatggctaa agccgggaga attaaaaaac
    16621 ttatgttcaa agatggttct ggtgcataca ggattcatct tggtcaaaat gaagttgttc
    16681 atattattcg cttcattctt aactctaaag tcaggatgga gtacgccgtt gggactacta
    16741 aaagtatgtc aatgctccac aatctttgcg aggcaggacg cgctaaatta aaccgctcat
    16801 taccacgtaa aggtatctgg aaacttgggt actatgatgg tgtttattat cacggtaagg
    16861 caagaaagga ggaaattgaa aatgctatgc gtttctcagt tcatccaaaa tttgacgagc
    16921 tggaaaacga ctttaatcaa ttcttttctg atattgattt ctatacccgg tatggtcagt
    16981 caggtatgcg taaagtgctc tttactggcc ccccaggaac aggcaagaca actatcgcaa
    17041 aagctttggg ggcaaagtat caggataagt atgtttttgt ttatgccgat gattacttta
    17101 aagatgtttg ctacgccgct gctcagaaga aaatacccgt cattattata gctgaagagg
    17161 ttgatgaact ttatcgggct gatgccggaa cgttaagttt tcttgatgga gctgatacac
    17221 cgcgaaatgt cgcaggtaca tatgtgatct tttctacaaa ctatccaaaa cgcatcgacc
    17281 cacgcatcag aaaacgtcca ggtcgaattg acaggataat ctctgtaggt gctttcagaa
    17341 ccaaagccgc tgccgcttgc gccaaaatgt acttaccaga agatgtagaa attgacctta
    17401 aagagcttgg cgcagtgctg gacagaacga ctccggctga aatcaaggaa attattaata
    17461 tcgcaatcgg aatgattcgc ggaaccaaaa atgaattatc agtggatgta ataaaaaatg
    17521 ctcgtgcctt tttgaaagga acccttgatc tgagcgtgca ggaagcagat gaagatatag
    17581 aggaaaggga agagctttat aaaaagaacg gggcgcaacc tgactattta agttacctgg
    17641 aggattaaca catgcaatat gcattagttg atgcgctgga acgaaaattt ttgctggatg
    17701 ctcttgaatt tggtgttctg aaggactgga aagaaaatcc ggtaaaagaa cttcctgata
    17761 ttgatgaatc tgttcacccc ttccatgtct gctatggtgg atatttatta aatcctggtg
    17821 tttcagattc agatattagc agaaaaataa aagaccagac aggattctgg ctggcagcta
    17881 ttgatgatac ccgcatggat tgtcattcaa tagcttatta tgatattcac accctccctt
    17941 tgattttgtg tggacatcaa aagatagttc cttttgccgc attaataaaa gctgatgaat
    18001 gcatcatttc aaaaattgct tcatattctg gttttgctgt aacagctttt ttgagaatta
    18061 aagaccagga tatcgcaacg aatatactta accgtgaggg aatttttgcc tttaatggct
    18121 gtgagcgcag attcagacaa cctgtaagtg aagataactg gcaacaggca gtatcagaag
    18181 aacgcgctat tcgttgtgca aacagattaa ttcaatgtaa aggataacaa aatgagactt
    18241 tttatcgcag aaaaacccgc agtagcaaat gatattgtta aggcacttgg tggcaatttt
    18301 acccgccatg atggctggtt tgaaagtgat aacgccattg tgactaactg ttttggtcat
    18361 attatcgaat cacaaccgcc ggaaaactat aatcctgaat acaaagcctg gaaggttgaa
    18421 acgcttcctt tacgtcttta tcccgtgaag tatcagcctg ttgaaagtgc agcaaaacag
    18481 gttaaaacga ttctcgaact tatcagacgt ggagacgtga ctgaaattgt tcatgctggc
    18541 gaccctgatg aagaaggtca gctacttgtt gatgaagttc tggaatatgc ggggaacaca
    18601 aaacccgtta agcgcgttct gattaacgac aacacgcttc cggcagtgaa aaaggcactg
    18661 gcaaatctta aagataatcg tgatttcaaa gggctttacc ttaaggcgct ggcgcgttca
    18721 gttgctgatg ccgtctatgg cttctccatg acgcgtgctt acaccattcc tgcaatagcc
    18781 agaggatata agggcgttct gtctgtcggg cgcgtccaga cacccattct tggcctgatt
    18841 gtgaatcgta cccgcgctaa ccagaaccac aaatccagtt tctactacac catgaccgga
    18901 gtctttcagc gtggtgctga tgttatcagg gcaaactgga aaccaggcga atttgctccg
    18961 ctgacagatc gtaaattgct tgataaggca tgggcaaacg gaacggctgc atcccttgca
    19021 ggaaaaccgg ctacagttga agcagcagca actgatgata aaaaaacggc tgcaccattg
    19081 ccctttaacc tggtccggct tcagcagtac atgaacaaaa agttcaaact gacggcacaa
    19141 aagacgctgg atattacgca gcaactacgc gaaaaatata aagcgatcac ttataaccgc
    19201 tctgattgtt catatctttc tgatgaacaa ttcagcgaag cgccgcaggt tatcgatgcc
    19261 ctgaagtcag tctttcctca gtcgctggat attgattctt cacgtaaaag caaagcgttt
    19321 aacagtgcaa aggtgactgc gcatactgcg ataatcccga ccgccagtgt gcctgatgtt
    19381 aacgcactca gcaccgacga gcgcaatgtt tacctggcga tcgcacaaca ctatcttgtt
    19441 cagttcatgc ctgaaaaagc ataccaggaa gtatcggttg ccattcagtg tggtgatgag
    19501 tcgttctgtg cccgtgccag aaaaacaact gacagcggat ttgaggcgtt tcttggcgcg
    19561 gaaaccacag acgaaggtga atcagaagat aatgatgatt ccgcttttga actgctctgt
    19621 aaaattcgca caggagaaac actgacgaca aaagaagtgg ttgtgaatga gaagaaaacg
    19681 acaccgccgc cattatttac tgaggcatca ttgcttgctg cgcttgttcg tgtcgcggat
    19741 tttgtcaccg atccaacgat taaaaagtta ctgaaagata aagataagga caaaaaagat
    19801 gaacatggcg gcattggtac gccagctacc cgcgccgcta ttctggaaac gttgaagaag
    19861 agaaattata tcacgctgga aaaaggaaaa ctcattccga cagataccgg atatgcgctt
    19921 attgatgccc ttccctctat tgcagtaaac cccgatatga ctgcattgtg ggctgaaaag
    19981 cagacagcta ttgaaaatgg cgatctgacc gtcgaacagt tcattaatga gctttacggt
    20041 gaactggcag acatgataac tgatgttgac ctgggtgata tgaagattga acccgcagcg
    20101 ccagcgggac aatctcagcg actggagtcg ccctgccctt catgtggcaa acaaattgtt
    20161 atcagaccaa aaggttattt ctgtacagga tgtgaattta aaatctggaa tgagttttct
    20221 ggcaagaaaa tcacccaggc acaggccgaa aaactggtta aatcaggaaa aaccgatttg
    20281 attaagggat ttaaaaagaa aagcggtgga acgtatgata cagttcttgt acttgaagat
    20341 aagaaaacag ggaagctggg ttttccggca agggttaaga agtgaaaaca aagcaggaat
    20401 ggctttttca gttaagaaaa tgtacatcaa gagatactct tgaaaaagtt attgatatta
    20461 accgttacaa actgccttta tcagaatcag aggcatttta ttctgccgca gatcatcgtc
    20521 gcgcagaact ggttatgaat aaactttatg ataaggttcc ttccggtgtc tggaagtacg
    20581 ttcactaaac aagaggatta attatgagcg aactgactaa agaagatgaa tacggcatta
    20641 tcagccggac tatgatgaat attcgttcat tgcgtgtgtt ttcccgtgag attgattttg
    20701 agcagttgct cgaaatgcag gaaaaactga acgttgttgt tgaagaacgt cgtgaagatg
    20761 ctgaacgtga agcggctgaa cgccaggaac ttgaagccaa acgtcagcag gccattgaat
    20821 acatcatatc tttaggtctt gatcccgaat cactccttgc tcctgtaaca gcagatacag
    20881 taaaaaccag gcggaaagct aaaggcggag taagaaaggc taaataccgc tttaaggatg
    20941 aaaatggcga gatcagagaa tggtctggta atggcaagcg tccgcttgct ttacagaagc
    21001 tgcttgatga ggggcatttc atggaagatt tcctcattga gaaaactaag ccggaacagg
    21061 cagaataacc cgccaggtat acatcacaca gacatacaca taggtatgtc tgtgtgacat
    21121 atgtatgtac agtgccagat ggcgttgcta cgtgaaaaat aacctaccct acccctgctt
    21181 ttttcgcaga ttttacgtag cacaccgttg ctatagcatt catctaaaaa gctgaatgtc
    21241 cttagaccga agaaccaaca gacaaaggcc gcgtaagtgg cctttaattg ggataccttt
    21301 tagttacaac attctaatag ttcattccat cctccgctca tccagcaaac ataacctccc
    21361 tgcccctccc cactacagaa agggcgcgcc ccgcccgtac gggcggaatc taatcgctta
    21421 attttgaatg ttgtaactaa gcatattcat tgctgtattg ccacaaggtt tcgcagcaag
    21481 ggaggatacc gaaagtaacg ctgtcacttt tgctttcaag tgaccaacca acgagtacat
    21541 cacactgaca tacaataatg tatttcttca tgatgtacat tattgtaatt cattgtgaca
    21601 tacactatag tatttccatg tgacatacgt ctgcgtacat cacatggaaa tacacatgag
    21661 taaatcactg tgacatacaa gaggtactat gattatcgta atcggtggtg ataaaggcgg
    21721 tacaggtaaa tcacatctgg caaccaactt aactgtttgc ctctcacaac agggaaagag
    21781 aacggggctt gttgaaacag acctgaatgg ctcgaccaaa aaatggaata aacgcagaga
    21841 acaggccgga ttaccgcccg tcgcgttaaa tgaagcctat ggcgacatca gtgccaaaat
    21901 aacaaaaatg gcggatgtag ccgaaatcct cattatagat actgccggat atgacagcac
    21961 ggagttcaga actgcactaa aagttgcaga cattgtgatt gtcccgatcg acccgcttgc
    22021 ccaggtggaa gcagacagtc ttcagactgt gacaaaaatt gtcagggatg cgcaaaaaat
    22081 aaatcccagg ctggctgcac atgtgctcct gtataaatgc cagccaaata cgttcagtga
    22141 acaacaggaa ttaagagact ctctcaacag ccatgattac tggcttaaac caatgaaaag
    22201 cacggtttct tttctccggg cctttgtaag agcaatgaat cagggaatgg gggttcacga
    22261 gttaaaaagt aatgttagcg gtgccagcca ggcaaaagca caaatcgaac ttttgctgaa
    22321 agaactggaa ctgtaaatca cagtgacata cactaatgta catcattatg aaatacatta
    22381 gtgtgaaaca atcagattag aaggtacatc atggcaaagc tggaactacc agaactagaa
    22441 caaaaccagg aagtgaacgc cacaaaattt gttcaggacg caggaaaacg ccccacagag
    22501 aacaaaacaa aactggcttc attccgcata ccgaatgaat tgcttgaatt cattgataac
    22561 gaatcaaaaa gactgcatcg ccccaagaca aagataatca aagcagcatt actggcttat
    22621 caggatctgg acgaaaacga actcattaat ttgtggttca gagctgacag aaatgattaa
    22681 cttctcacgg aggagtttaa ctctatgaaa caatgcatct ttgatttagg catcatgaac
    22741 tatgatgccg tcattacatg gactgtacca gttgtatttt tctttttagt gttactggct
    22801 ggtatagcat ttaatattgg caggaaaagt aatctgattg tttttgccct ggcaatgttg
    22861 ctcccagtaa caacggtttt catttttatg ttactgggcg gtaagatcga tatgtgctga
    22921 tcaattaaaa gaggattaaa caatgataaa ttcaatcgcg tttagtctta tagcgttatg
    22981 tataatatat atatcatcac tacttaaaaa aagtaacttc agaatgtttt atataactgt
    23041 atctacgtgc tctttattat tatcatgtgc accaaacaag tacggtatga ttggtatagc
    23101 agcattggta tttacaacta tgttaggacc attattaatt attttagagg ataacagaca
    23161 ataaattatg acaatgcgtt tgttaagccc gcaaatatgt gggcttattt ttaattactc
    23221 ttcatcatcc cgcaggaact gacaaaagtc ttcgctcccc atcatatcga ctgtgttttt
    23281 aaattcgaaa aaagaaattc ctgtcatagc acacacgcgc tggataatca gttttttctt
    23341 ttgctgtctg acggttgcgg tttcaccaaa ctggataaca gccaggactg tttcatcata
    23401 tgatttcagg acaaaatcac aggttatatt ctgcacttca cggattaaat cttttacagc
    23461 ttcctcgcta ccatgaggac gaacaaattc aatgagccgt attttgggaa aaacggaata
    23521 atcaggtata atattacgtg aaagaatgcc taaaaactct gattccttat ttgagagtaa
    23581 gggtacttta gtaaaacaat caacctcccc aatggctgta aaagcattgg ttatcaaagc
    23641 tggattattc ttaataaaat cagagaatac gttttcagtt gatggcaaaa caacagcaga
    23701 attatgttgt tcatctcgtt ttttattacg gttaaatatc atttcatatt ccttttaaaa
    23761 gagcctgcgg caggcacagg caaaaaccct gtttttggac aatccgatat cgaatggtac
    23821 catttgacat cggattgtct atcctgcatt gttctttact gcctgtaaga tcggcgctca
    23881 ttcttccggc gttctcccga taccaaaaag acggaacgca aaacggcttt cgatccacca
    23941 ttcaaaaatc tgctctgcgc aaccacaaac agttaaggcg atccatgcag caagaacaac
    24001 gtaaccactg acatctgcac ccatgtacca ggcgatagtt aaacccatca ctgcgatacc
    24061 gcctaaaaac tgcaacaaga aacgaaatcc cgcaagaatc cccaatggaa taacgacaac
    24121 cagataaagg gaagcagcca gaaggtatct gacaggtgtc agcagataaa agaacctgga
    24181 tattttcttt ttgtcagaat aaacggcatc atttgcaaca tctgttgaat gagcgcccag
    24241 gtctctcctg atacgttgaa aatccacgac gttatctttc atattgttat gacctcagtt
    24301 ttcagattca ggcatacctt cttcagggaa cacgttttct tcaataacaa attcaaagat
    24361 caaactacta accttccttc catctttttt atatgttgca catgttaatt ctttaacttc
    24421 cgtttttttc tttatttcag cgatagcttt attcaacaca tcgcgtttaa atatcgggaa
    24481 atcagggtac ttatactcta ttgttccatc atctttaaaa gtataggcga taatttcctc
    24541 tttaagttca ttcagggaaa tgatgaaact atttttgcca gaaaacttcg agtgatattt
    24601 tcttatcaac tgatacaatg cagatgaata ttgaccgctc aatctcagac aagacgtcaa
    24661 tagctgtgta gtaaatttat atttgttacc cagcaaactt gatatgtaag gctcaatgac
    24721 gcgagaaaat cttaactcca gatagccttc attattaaaa tatgcacaat aatctgttat
    24781 tgataaatca atttcagatg gcctgttcct ggaaccataa ggtaaattta gttcatcgga
    24841 gagagctata atatcatcac cagtcaaagt taaactacta cctcttaata actttgcacc
    24901 atcttttaat tgtttatacg ctacagatat ttcaatatcc gccgcagacg ctaaatcatc
    24961 tgctctgacc ctgaatacct gacctgtttc tatcggctta cgactatcaa cagaggctaa
    25021 cgccatatac ataacccgct ttgctgcgag tggtaactgt gcaagcgtta aattcagttc
    25081 atttcgatgc cggattttag ttttttgagc caggttcata taaatattca gcttcatcat
    25141 cattccacct gtagatgaca tcattctacc acccaaaaac atgagatcaa cataaaatca
    25201 ctcatgttta atggcaaatc ctctcatgtt tgagagcaat caaatttcac ccgcacatag
    25261 ttcttgttta gattcaccct aaatctattt gggattcaaa acgaatccgc tttgcttgtg
    25321 gatatgatgt gcataaagct gtatataact catgtataag ctgttaattt aacggcaaat
    25381 cctctcatgt ttaacggcaa atcctctcat gtttaacggc aaatcctctc atgtttaacg
    25441 gcaaatcctc tcatgtttaa gtctaaaaaa cgtttttttt caaaatgtta cagccctctt
    25501 aagtttttaa gaaaagataa gaaaagaaaa ggatctttat aataaagcaa caccataaat
    25561 ctgtcccccg atgtcattgg cagacaaact gaaatctaca cattcaataa ctcaaaccaa
    25621 ttacgtgtcc ttttaagtat atgaaattaa aattattatt ggcttttccg ttaaattctc
    25681 tgccaatttt aagcgtcata aacaacctct tttccaacca taaatttgtc cctggttagc
    25741 tttcaattat ttgaaataaa aaggaaatat aatatccgtg cgtacggatt catatgcagc
    25801 atcgaagaca ttccgcttcc tcgctcacta actcgctccg ctcggtcgtt cgactgcggc
    25861 gagcggagtt atttctcaca tatcgctggt aattctgttg ttgttccttc ggtgataagt
    25921 cgcttgatag cctctaaaac acgctcagaa gctctcagac gcacgaaacc gggttaaata
    25981 cccctcaggg catgggaggc atgaaaaacg cttacagagg ctttctgttc atcagaatca
    26041 tgatcctgtg aagaccgaga aagttctcat gtttagttac aacctgaata tttcattccg
    26101 agggtggttt aatataacta actgatttta ttgagttctt tgaaagaatt tttttaatta
    26161 tgatcctcat tttgctaacc gaggatcttc tcatgtttca ataaaatacc tttaatatca
    26221 acattatata ttcttttatc aattggttta tgtgaccaca tcatttcaac gatacataaa
    26281 tcaacagatc cagtaatgcc ccctccccaa agtgtcacag agaagccctg aatcgcgctc
    26341 tgccgcttcg ttcggtacaa ccatgaggga aaccatgcaa aataaaaaaa aatcgcttag
    26401 aacgcgttac agagcgtttt agggaggttc tgttagttct cctgcattgc gcccgtagtt
    26461 cgctgacgct cacacgcgca gtacagcgcc ccgtccaggg aaatcctgga cggcgtaaac
    26521 tcgctggcgc gagcgctaac tgcggcattc tgcggcgcaa atcagcgtca tcgttgtctg
    26581 cgagtcagtc gggcttagca gggcgggaag gtggtcgtgg ttccggtcgg ttacggtagc
    26641 ggcgttgccg cgtttcgggg cgatgtggct cctgtgctgc cctggtattt tcgttcgccc
    26701 cttccatccg cttacgcgga ttaaaaaacg tgataacaat cacttatcga gtaaaaaaac
    26761 ggaagaacac ttgcaaatac gacctgagag tcgtattatt gtttcatcga aaggggaatg
    26821 gcccctctca caatagccca gcagggcagg agatttaaaa aatgaatatc caggaagcat
    26881 taaacgtttt tggattatcc ggcgaattaa ctgaaaaaga tatcaaagca gcatacagaa
    26941 aagccgcttt aaaatatcat ccagatcgta acccgttagg ggctgaactg atgaaagcgg
    27001 taaatgcagc ttttgatgta ttgatggcaa atattgataa aataaatcag ttccagagca
    27061 ccgatgaaca tgcacgatat aattacggtg atgacctgga aaaagtatta aacgttcttt
    27121 ctggtttatc tggtctggta tttgaagtga taggtaactg ggtctggatt agtggagaaa
    27181 ccattacaca taaggaaact ttaaaagaaa tcgggtgtaa atgggcggca aagaaaaaac
    27241 aatggtttta tcgtccagac gaacataaaa gttactggaa tcgtgaagaa cacacgatag
    27301 aagaaatccg cgcaaaatac ggtacaaccg gacagcgcag ggcgacaggg tggcaacgcg
    27361 tggaaaccag agcgtaacca gaacgggggc gagaagcccc cgatattata gccagcccgt
    27421 cttttggggc atcgaaccca aaaagacggg aacagcagcc acgtagcaaa aagggaaaca
    27481 gatgaactct ttttttgaac aatatcaccc tgtctttgaa gttgtctgcc gtatcctggg
    27541 gaacggctgg cgcgtgaaca aacttgatga ttgttcgtct cgtataaaac tgacgtcacc
    27601 gcagtttaaa aattactctg tgcatattcg gatggaaaaa gaccggtttt ctgttgtggg
    27661 gagtgtggat agtcgctcct ggcgtagtcc gcatcatgtt tgcacgttat ccagaaaacg
    27721 gaatcccgtt gatattgcag ccgatatcga gcgaaaaatt ctggtaaatg cttcgcagga
    27781 ggtgttacag gcgattgagt atgagaaaca ccaggtggaa aaaaaggacg aaattctgat
    27841 cctgaaaggt atgttatcgc aacttgtcca gcttgaaagc tggtatgggg cattgacagg
    27901 ctttaaagct gaaaacggat tgaatggtaa agtcaccgaa cagggcgaca gttatgattt
    27961 acagattcgg ggcttgagta tagatcaact tgttaaaatt acagggtatt tgaaacagtt
    28021 atgagaaaaa ataaaggtga tgtgacttat tttcttgaaa aagaaggtga caattacagg
    28081 cttacaaaaa ggataaaagc cagaacaaat gttaaaatcg ggaacaaaac tacgaaaatc
    28141 acattgtatg atgccgtgct gaatgagaat gaattacaac atattgattt tacgtgtgcc
    28201 ggattaaggg aagacgatga gacgccagtt aagaatttaa ttaaggagtt tatgttaaat
    28261 gaaacccgat aatacacctg aaaatgtaaa aaaattacgt ttaaaagcag gattaacaca
    28321 aaaggaatgc agtcatattt atggtgttgg gctaagaacc tggcagaaaa aagaggaagt
    28381 taatactcaa aacagtcaaa gtctgtcact ggttgagttt gagtttcttt tgttacttgc
    28441 aggagaacat cctgaatacg tgctctgcaa aagggagtca aaataaaatg acctgtgatg
    28501 gttttatatt agtacctgga gttgcgcccg tagctcgctg gcgctcacac gcgcagtaca
    28561 gcgccccgtc cagggaaacc ctggacggcg taaactcgct ggcgcgagcg ctaactgcgg
    28621 cattctgcgg cgcaaatcag cataatcatg gcctgctggt cagttgggct ttgcagggtg
    28681 aagggatggc ctgtgcaccc tggtacgttc gtcagcggct gcgccgcgct tcggggcgat
    28741 gtggctcctg tgctgccctg gtattttcgt tcgccccttc catccgctta cgcggattaa
    28801 aaacgtgata acaatcactt atcgagtaaa aaaacgggag aacacttgca aatgcgactt
    28861 aaaagtcgta ttattatttc atcgaaaggg gaatggcccc tctcacaata gcccagcagg
    28921 gcaggagatt taaaatgagt gcatttgttt tcagaaccac ctttaaaccg actggcgacc
    28981 agcaaaaaga tgctattgcc cacatcgaag ttatgcagga acgagcagta aaagcctttg
    29041 tttcctggat gagctgccag gaatgttcag attttttaag caatttgcag gaaatcacaa
    29101 cagaacttaa ttcactgatt gatgcggtag agtcccacac ccctgttttc agaaagaaag
    29161 ctgatgaact ggaagcgctt ttagctcatt acaaaacgtt gctgtaagtc ctcaacgggg
    29221 catttgcccc gttatccggt ccttaattta atctaaaaca ggtggagtta aaaaatggct
    29281 cgcttacctt tcattgaatc aaccacacaa cagatttttg tttttaatac tttgacgctt
    29341 tgtactattg gattaattca tttggagact gaaaaagaat atgttgtagt gtttacagat
    29401 aataataaga ttcgggatta caaaaccgga attgttactc agtttggtga acttaagcag
    29461 agtgatattg atttaatcct tttctatcgg gacgaatatg aaaaatattt tgactcttta
    29521 aataacggcg aggagtattt gagttttaaa gaatatatcg gatgtataag gggggaataa
    29581 attatgagag gtgtgttcag gttgctggaa caacctgaac acgttatcga caatcaaaac
    29641 tgaatgaggt ttttaaatgt caacacgaca gatcgtacag cttgctgatt ctcttgtcaa
    29701 aggctgggaa accagaatcc cagcaatgac gtttagtgag tgggatcaat tccggtggtg
    29761 gttaaactac ctgcaagggt atgaaatgtt ttaaataaaa aaaggggctt tctgcccctt
    29821 tgtatttttt gacaaaaatg ctatgtgtaa ctataattag ttgcatatct ataggggatg
    29881 gatttatggg gaaaacagat aagctactgg caaagttttt aaacagtaaa aaaacgtttg
    29941 aatgggatga actggtcgtt ttgttttcct ctttgggata tgtcaaaaag gaaatgcagg
    30001 ggtcaagagt gcggtttttc aatgctgaaa tcaatcacac catattaatg catcgtccac
    30061 atccggaaag ttatatcaaa ggtggtacgc tgaaagcaat taaacagaat ctgaaagagg
    30121 ctggattatt atgaaacatt taaaatataa aggatattta ggcacggttg aacccgattt
    30181 tgaaaataat gtcctgtatg ggaaactggc gtttattcgg gacctggtaa cttatgaggc
    30241 ttctacatta gctgaactgg aacaggagtt taaaacatct gttgatctgt atttacagtc
    30301 ttgtgtggag gatggaaagg aacctgatac cccgtttaaa ggcgtgttta acgtcaggct
    30361 tgatccagaa ctgcatcgtc gggtagcaga aatggcgatg gaagaagatt tatcactgaa
    30421 cgcctttgtt aataaggctc tggaaaaaga agtcagcaat catcgcgcag gggcttaatt
    30481 gcccttgttt cttatgccct gtaagggcat gggaggcgct ttgcgccgga agccccgcag
    30541 cgcagcgagg acttaaaaag cgttacggct tcagccgtaa caattcccag ccctgccagg
    30601 cttgtttttt ctttcacaaa tctttcagct atacgtttgc cagatggtcg aagacgaaag
    30661 aacctttcag caacgaaatc tggacatatg cagcgacgat tttatagcca ggcacagcgc
    30721 cacatatggt acaatcaatg caggatagac aatccgatgt caaatggtac cattcgatat
    30781 cggattgtcc aaaaacaggg tttttgcctg tgcctgccgc aggctctatg gagtgaagat
    30841 gaaacagata aaattcagag ttagtgatga tgagttaaaa cttgcagaac ataacg
//
