LOCUS       NZ_CP115475            25430 bp    DNA     circular CON 08-JUL-2023
DEFINITION  Staphylococcus aureus strain AF4005 plasmid unnamed, complete
            sequence.
ACCESSION   NZ_CP115475
VERSION     NZ_CP115475.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN32369493
            Assembly: GCF_030408975.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 25430)
  AUTHORS   Pitcher,N., Feder,A., Bolden,N., Zirbes,C., Pamatmat,A., Boyken,L.,
            Hill,J., Thurman,A., Reeb,V., Porterfield,H., Moustafa,A., Planet,P.
            and Fischer,A.
  TITLE     Parallel Evolution of Linezolid Resistance in Staphylococcus aureus
            from Patients with Cystic Fibrosis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 25430)
  AUTHORS   Fischer,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-DEC-2022) Department of Pediatrics, University of Iowa
            Hospitals and Clinics, Newton Road, Iowa City, IA 52246, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: GS De Novo Assembler v. 1.1.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 102.02x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 07/08/2023 07:07:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,973
            CDSs (total)                      :: 2,894
            Genes (coding)                    :: 2,808
            CDSs (with protein)               :: 2,808
            Genes (RNA)                       :: 79
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 52 of 86
            Pseudo Genes (incomplete)         :: 37 of 86
            Pseudo Genes (internal stop)      :: 26 of 86
            Pseudo Genes (multiple problems)  :: 28 of 86
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP115475.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..25430
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="AF4005"
                     /isolation_source="Oropharynx"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed"
                     /geo_loc_name="USA: Iowa"
                     /lat_lon="41.6578 N 91.5346 W"
                     /collection_date="2017-11-27"
     gene            81..698
                     /gene="cadD"
                     /locus_tag="PDI58_RS14720"
                     /old_locus_tag="PDI58_14720"
     ARG             82..695
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            717..1064
                     /locus_tag="PDI58_RS14725"
                     /old_locus_tag="PDI58_14725"
     CDS             717..1064
                     /locus_tag="PDI58_RS14725"
                     /old_locus_tag="PDI58_14725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            1221..1313
                     /locus_tag="PDI58_RS14730"
                     /old_locus_tag="PDI58_14730"
     CDS             1221..1313
                     /locus_tag="PDI58_RS14730"
                     /old_locus_tag="PDI58_14730"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(1485..2456)
                     /locus_tag="PDI58_RS14735"
                     /old_locus_tag="PDI58_14735"
     CDS             complement(1485..2456)
                     /locus_tag="PDI58_RS14735"
                     /old_locus_tag="PDI58_14735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            2580..2999
                     /locus_tag="PDI58_RS14740"
                     /old_locus_tag="PDI58_14740"
     CDS             2580..2999
                     /locus_tag="PDI58_RS14740"
                     /old_locus_tag="PDI58_14740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(3513..4358)
                     /gene="blaZ"
                     /locus_tag="PDI58_RS14745"
                     /old_locus_tag="PDI58_14745"
     ARG             complement(3517..4358)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.29"
                     /coverage="100.0"
     gene            4465..6222
                     /gene="blaR1"
                     /locus_tag="PDI58_RS14750"
                     /old_locus_tag="PDI58_14750"
     ARG             4466..6219
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.8"
                     /coverage="100.0"
     gene            6212..6592
                     /gene="blaI"
                     /locus_tag="PDI58_RS14755"
                     /old_locus_tag="PDI58_14755"
     ARG             6213..6589
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            6856..7434
                     /locus_tag="PDI58_RS14760"
                     /old_locus_tag="PDI58_14760"
     CDS             6856..7434
                     /locus_tag="PDI58_RS14760"
                     /old_locus_tag="PDI58_14760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(7657..7842)
                     /locus_tag="PDI58_RS14765"
                     /old_locus_tag="PDI58_14765"
     CDS             complement(7657..7842)
                     /locus_tag="PDI58_RS14765"
                     /old_locus_tag="PDI58_14765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            8104..8778
                     /locus_tag="PDI58_RS14770"
                     /old_locus_tag="PDI58_14770"
     CDS             8104..8778
                     /locus_tag="PDI58_RS14770"
                     /old_locus_tag="PDI58_14770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(8947..9518)
                     /locus_tag="PDI58_RS14775"
                     /old_locus_tag="PDI58_14775"
                     /pseudo=""
     CDS             complement(8947..9518)
                     /locus_tag="PDI58_RS14775"
                     /old_locus_tag="PDI58_14775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(9794..10588)
                     /gene="aph(3')-IIIa"
                     /locus_tag="PDI58_RS14780"
                     /old_locus_tag="PDI58_14780"
     ARG             complement(9798..10588)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(10681..11211)
                     /gene="sat4"
                     /locus_tag="PDI58_RS14785"
                     /old_locus_tag="PDI58_14785"
     ARG             complement(10685..11211)
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            complement(11208..>11843)
                     /locus_tag="PDI58_RS14790"
                     /old_locus_tag="PDI58_14790"
                     /pseudo=""
     CDS             complement(11208..>11843)
                     /locus_tag="PDI58_RS14790"
                     /old_locus_tag="PDI58_14790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            complement(11984..12658)
                     /locus_tag="PDI58_RS14795"
                     /old_locus_tag="PDI58_14795"
     CDS             complement(11984..12658)
                     /locus_tag="PDI58_RS14795"
                     /old_locus_tag="PDI58_14795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            complement(<12715..12891)
                     /locus_tag="PDI58_RS14800"
                     /old_locus_tag="PDI58_14800"
                     /pseudo=""
     CDS             complement(<12715..12891)
                     /locus_tag="PDI58_RS14800"
                     /old_locus_tag="PDI58_14800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            complement(12905..13642)
                     /locus_tag="PDI58_RS14805"
                     /old_locus_tag="PDI58_14805"
     CDS             complement(12905..13642)
                     /locus_tag="PDI58_RS14805"
                     /old_locus_tag="PDI58_14805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_190362697.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFVSMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            complement(13635..14564)
                     /locus_tag="PDI58_RS14810"
                     /old_locus_tag="PDI58_14810"
     CDS             complement(13635..14564)
                     /locus_tag="PDI58_RS14810"
                     /old_locus_tag="PDI58_14810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(14680..15561)
                     /locus_tag="PDI58_RS14815"
                     /old_locus_tag="PDI58_14815"
                     /pseudo=""
     CDS             complement(14680..15561)
                     /locus_tag="PDI58_RS14815"
                     /old_locus_tag="PDI58_14815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            complement(15558..>15935)
                     /locus_tag="PDI58_RS14820"
                     /old_locus_tag="PDI58_14820"
                     /pseudo=""
     CDS             complement(15558..>15935)
                     /locus_tag="PDI58_RS14820"
                     /old_locus_tag="PDI58_14820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            complement(15993..16667)
                     /locus_tag="PDI58_RS14825"
                     /old_locus_tag="PDI58_14825"
     CDS             complement(15993..16667)
                     /locus_tag="PDI58_RS14825"
                     /old_locus_tag="PDI58_14825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            17141..18607
                     /gene="msr(A)"
                     /locus_tag="PDI58_RS14830"
                     /old_locus_tag="PDI58_14830"
     ARG             17142..18604
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            18706..19605
                     /locus_tag="PDI58_RS14835"
                     /old_locus_tag="PDI58_14835"
     CDS             18706..19605
                     /locus_tag="PDI58_RS14835"
                     /old_locus_tag="PDI58_14835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            complement(20074..20817)
                     /locus_tag="PDI58_RS14840"
                     /old_locus_tag="PDI58_14840"
     CDS             complement(20074..20817)
                     /locus_tag="PDI58_RS14840"
                     /old_locus_tag="PDI58_14840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            21243..22226
                     /locus_tag="PDI58_RS14845"
                     /old_locus_tag="PDI58_14845"
     CDS             21243..22226
                     /locus_tag="PDI58_RS14845"
                     /old_locus_tag="PDI58_14845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            <22246..22535
                     /locus_tag="PDI58_RS14850"
                     /old_locus_tag="PDI58_14850"
                     /pseudo=""
     CDS             <22246..22535
                     /locus_tag="PDI58_RS14850"
                     /old_locus_tag="PDI58_14850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            23082..23231
                     /locus_tag="PDI58_RS14855"
                     /old_locus_tag="PDI58_14855"
     CDS             23082..23231
                     /locus_tag="PDI58_RS14855"
                     /old_locus_tag="PDI58_14855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(23399..24091)
                     /locus_tag="PDI58_RS14860"
                     /old_locus_tag="PDI58_14860"
     CDS             complement(23399..24091)
                     /locus_tag="PDI58_RS14860"
                     /old_locus_tag="PDI58_14860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            24201..24395
                     /locus_tag="PDI58_RS14865"
                     /old_locus_tag="PDI58_14865"
     CDS             24201..24395
                     /locus_tag="PDI58_RS14865"
                     /old_locus_tag="PDI58_14865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_216798522.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLVVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     ARG             18707..19602
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             17142..18607
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             18707..19605
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(10682..11199)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             complement(3514..4358)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="95.37"
                     /coverage="100.0"
     ARG             complement(11506..11807)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     Typing          22592..22739
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(20075..20817)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          21244..22226
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          22358..22527
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
ORIGIN
        1 gcaattggaa taaagcacct atgattattt aaaaatataa gttataatac attcaaaaat
       61 atttttgaat gaggtgtatt atgattcaaa cggttgttgc tgctgctgtt ctttatattg
      121 ctacagcagt tgatttatta gtaattttat taatattttt tgctagagca aagactagaa
      181 aagaatatag agatatttat gttggtcaat atttagggtc tattatttta atattagtta
      241 gtttgttttt agcttttgta ttaaattatg ttccagaaaa gtggatatta ggtttattgg
      301 gtttaatacc aatttatctt ggaattaaag tggctattta tgatgattgt gaaggagaaa
      361 agagagctaa aaaagaattg aatgaaaaag gattgtctaa attagttggt acggttgcaa
      421 ttgttacgat agcaagttgt ggcgccgata atattggttt atttgttccg tattttgtga
      481 cattaagtgt tactaattta ttacttactc tgtttgtctt tttaatttta attttcttct
      541 tggtgtttac tgcacaaaaa ttagctaata ttccaggaat tggagaaatt gttgagaaat
      601 ttagtcgttg gattatggct attatttata tagctttagg tttatttatt attattgaaa
      661 atgacactat tcaaacaatt ttaggattta tattttaatt tagggtgtga ttttatatga
      721 gttatgaaaa tacttgtgat gtgatctgtg tacatgagga taaagttaac aatgctttaa
      781 gttttttaga agatgataaa tctaagaaat tacttaacat tttagaaaaa atttgtgatg
      841 agaagaaatt gaaaatcata ttatctttga ttaaagaaga tgagttgtgt gtttgtgata
      901 tttctttgat attgaaaatg agtgttgctt caacttcaca tcatttaagg cttttatata
      961 aaaatgaggt acttgatttt tataaagatg gaaagatggc atattatttt attaaagacg
     1021 atgaaataag agagtttttc tctaaaaatc atgagggttt ttgaaacgag tttcttcttg
     1081 tcttgatact ataaaaaaca aagttatata acataagacg acttatcgga agtagatatg
     1141 cttgtatatt cacagatggt ataataatag agtcgcctat ctctcaggcg tcaattgacg
     1201 aagagaggag gtgcattact ttgctaatca ttttcgttca catcatagca ccagtcatca
     1261 gtggctgtgc tgttgcgtat tatacttatt ggcttagtaa acgcaacaaa taattaatag
     1321 gcgactttat aagccagcat cgaaaaaatc cccacactac tgcaatagtg tggggattgg
     1381 tgcattaatt gttaatcatt ttcgttatat aaattataac actggttagt agagaaatgc
     1441 aaaatgattg aattaatagt aaatgtatta atgaatactc acacttatac ttttaaaata
     1501 gttcttccta aatgttgtcc ttttaaaagc tgatctatcg ttttatagaa ttcttcaaat
     1561 ccaatttcat tgtatagaag tgaatttcct atattccatt catttgctaa cttactccat
     1621 atatcttcac ggatattatg atcaacatat acagaatcaa tgccaattaa tttaatacct
     1681 ctaagaataa acggtaatat attagcgtta agtgaatttc ctgctacatt tccacataca
     1741 gtagcaacac cttgataatt tagacgtttt aaaccgtata atgttacatt actccccact
     1801 gtatctaaga aataatcaaa aatacctttt ttaagcggtt tattatcatc ttcaattatt
     1861 attacttgtt ttgcacctaa tttttttgcg atttctattt gcttttcttt tcttacgata
     1921 gcagtgatat tttcatatcc aattttatgt aaaatttgta tagcaacact gcccacacca
     1981 cctgtagccc cagacactaa aatttcaggt tgtgatttga tattcattcc atatttttct
     2041 agttcaaaaa ttgataatgc tgccgtaaaa ccggctgtgc catataccat agactcttta
     2101 atagacattt cttggggaat aggaacaatc cactctccag gcacttgtgc atattctgaa
     2161 aatccacctg tatgtgtcac gccaacatca taaccagtaa ctaatacatt atcgccttct
     2221 ttaaacttat cattcgaact tgattcaaca atacctgcaa aatctatacc aggaatcata
     2281 ggataatctc taattacacc gcctttatat tgtaaagcta gcatatcctt ataatttatt
     2341 gaagagtata ccacttttac taatacatca cccttcgata aatgagattc atcaactttt
     2401 tctactttat aactaacatt tgatgcactt tttctcacta ctaccgcatt gaacatttat
     2461 tagccttctt tcacaattgt tttgtagaag tatgtttttg ttgcaaaact attttcctac
     2521 aaaacttatc atgatatgat aagcgagtca atactaatga tttaagagag gttttagttg
     2581 tggaattaga taattgtata aattatttgt tgagtacttc tcagaataga gtttttaaac
     2641 attttaaaag tttattaagt ccctataata ttactccagc agaatatggt gttttgaatt
     2701 gcttgattaa tagtaatttg aatacaccta aagcgattgg taatacttta aatttagaac
     2761 cttcaacaat atctggaata ttagataaga tgtccaaaaa ggatctaata acacgtcaaa
     2821 ctgataatga aaatagaaga actgtgctaa taaacagtac aaataaagca aaagacttat
     2881 ggccaacatt agaaaagaaa gcctatcaac ttaataatca ttacttcgct aatttaacta
     2941 atgaagaaac tgtagtgttt aaaaagatat tactaaagat aaataaaact acgttttaat
     3001 ttttacgtta taaaaaagtt gaagtgcgaa ttataatcga gtaaatataa atgatagctt
     3061 agcttaatta tatattaaag ccaactatac ttttattccc gaaaaaccta ctatccaaat
     3121 ttctaagata ctttagcctc tataataaac atattgtaat ataatttatg tattatttag
     3181 gtttacccta atcgaacaat aaaaaatact tgtaaaatgc tattgtcact ttgcttgata
     3241 tatgagaatt atttaacctt ataaatgaga aaaaagcaac gcactttaaa taagatacgt
     3301 tgctttttcg attgatgaat acctataatt aaactattca tctattattt atgatttttt
     3361 gtatatacaa tatttctagt ttgttaaaga gaattaagaa aataaatatc gaaaataata
     3421 gagggaaaat cagtttttga tatcaaaatt atacatgtca acgataatac aaactataag
     3481 atgatatcag tatttattat gcatttagaa tattaaaatt ccttcattac actcttggcg
     3541 gtttcactta tcaacttatc atttggctta tcacttttat tgtctttatt cgtaaaaatg
     3601 actaaaacaa taggttcaga ttggccctta ggataaacaa aagcaacatc atttctagaa
     3661 gcatatgtta ttgcttgacc acttttatca gcaaccttac agtcttttga aacaccgtct
     3721 ttaattaaag tatctccgct tttattattt aacattaaat caagtaagaa ttttttgttt
     3781 tctttgctta attttccatt tgcgataagt ttatttaaag tcttaccgaa agcagcaggt
     3841 gttgaagtat cttttttgct ctttggtgaa taataattta attctatctc atatctaact
     3901 ggatttgtta ctttatctcc tagtcctttt agacgttgtt taactttttt gatcccaccg
     3961 atctctttta taattttatt gtttgctgta ttatcactat atgccattga agcctcaata
     4021 agttctttta aagtgatatc ttttcctaca tatttttcta aaataggaga ataagcaact
     4081 atatcatctt tgttaatatg tattttttta tttaacttat tataaggtac ttgttctaac
     4141 aaaatagcac tatttatcgc ttttgaagtc gaagcatagg caaatctctt atctgaatta
     4201 aattttactt ccttaccact tttagtatct aaagcataaa caccaatatg agcattatat
     4261 tttttttcta aatcatttaa ctctttggca tgtgaactgt ttgaattaca tgcacttaaa
     4321 actaaagcaa ttacaattaa aaatattaac tttttcaaaa taaaccctcc gatattacag
     4381 ttgtaatttt tataaatcaa taatattaca attgtaatat tgatgtcaat tgtttattat
     4441 aaatatttga aagaaggtgt caaaatggct aaattactaa taatgagcgt agtaagcttt
     4501 tgttttatat ttctattgtt agtatttttt aggtacatat taaaacgcta ttttaattat
     4561 agtttaaatt ataaagtttg gtatctaact atgcttgctg gattaattcc ttttatccca
     4621 attaaattct cttttataaa atttaataat gtgaataatc aagcgcccac agttgaaagt
     4681 aagtcacacg atttgaacca taacataaat accaccaaac ctattcaaga gttcacaaca
     4741 gatatccata agtttaattg ggattcaatt gataatatct gcacagttat ttggatagtt
     4801 ttagttatta ttttaagttt taaatttttg aaagccttat tatatcttaa atatttaaag
     4861 aaacagtcac tttatctaaa cgaaaatgaa aaaaataaaa tagatacgat acttttcaac
     4921 catcaatata aaaaaaatat tgtgattcga aaagcagagg ctattcaatc tccaataact
     4981 ttttggtatg ggaaatatat tattttgatt cctagttcat attttaaaag tgtaattgat
     5041 aaaagactaa aatatataat actgcatgaa tatgctcatg ctaaaaatag agatacttta
     5101 catttaatta tctttaatat cttctctatt gttatgagtt acaatccatt aatacatatt
     5161 gtaaaaagaa agataattca tgacaatgaa gtagaagctg atagatttgt tcttaataat
     5221 attaacaaaa atgaatttaa aacttatgcg gaatctatta tggactccgt attaaatatt
     5281 ccatttttta ataaaaatat attaagccat tcatttaatg gtaaaaagtc attactcaaa
     5341 agaagattaa ttaatataaa agaagccaat ttgaaaaaac agtctaaatt aattccaatt
     5401 tttatttgta tttttacttt tttgctcata gtaattcaaa gccagttttt gatggggcaa
     5461 tccataactg attataatta taaaaagccc ttacagaacg atcaccaaat tttagatgaa
     5521 agtaaaaatt ttggttcaaa tagtggatct ttcgtcatgt acagcatgaa gaaagacaaa
     5581 tactatattt ataatgaaaa agaaagtaga aaaagatatt ctcctgattc aacttataaa
     5641 atttatttag cgatgtttgg acttgaccgt catatcataa gtgataaaaa ttcacgtatg
     5701 tcatggaatc ataaacatta tcctttcgag tcttggaata aggaacaaga tttaaataca
     5761 gcaatgcaaa attcagttaa ttggtacttc gaacgtatta gtaatcaaat accaaagaac
     5821 tatactgcgg ctcaactcaa gcaattaaat tatggtaatg aaaatttggg aagttataaa
     5881 aactattgga tggaagatag tttgaaaata tctaatcttg aacaagtaat agtttttaaa
     5941 aatatgatgg aacaaaataa ccattttagt aaaaaagcaa agaatcaatt atcttcttca
     6001 ttattgatta agaaaaatga aaagtatgaa ctgtatggga aaacaggtac aggtatagta
     6061 aacgggaagt ataataatgg gtggtttgta ggttacgtaa ttacaaatca tgataagtat
     6121 tattttgcta cacatttatc agatggaaac ccgtctggga aaaatgctga attaatcagt
     6181 gaaaaaatat taaaagaaat gggtgtttta aatggccaat aagcaagttg aaatatctat
     6241 ggctgaatgg gatgttatga atataatatg ggataaaaaa tcagtatcag ctaatgaaat
     6301 tgtagttgaa attcaaaaat ataaagaagt tagcgataaa acaattagaa cattaatcac
     6361 aagactatat aaaaaagaga ttataaaacg atacaaatca gagaatattt atttttactc
     6421 atcaaatatt aaagaagacg atattaaaat gaaaactgct aaaacttttc ttaataaact
     6481 gtatggaggg gacatgaaaa gtttagtgct aaattttgcg aaaaatgaag aattaaataa
     6541 caaagaaatt gaagaattgc gagacatttt aaatgatatt agtaaaaagt aattagagat
     6601 atgtttcaaa cattatacat atgtaaacta tacttgactc ttattaaatt agttttgtta
     6661 ataacattta aaatatatta gtaaagatga gagtgtacat aaaataacca ttttctgtac
     6721 actctctttt tatgtctaaa taagtatgta ttacatagaa ttatgtgttc aaaaacccaa
     6781 caaaaaatct atgttcacaa aagacctcgt aatcaagtta tggtacacta aaggtgtata
     6841 taggaggtct gtattttgaa aataggttat gcaagagttt caactggatt acaaaatttg
     6901 aatttacagg aggatcgatt aaatacatat ggttgtgaaa agatatttaa tgaccatatg
     6961 agtggttcaa aaagtaagcg acctggttta gataaagcaa ttgaatttgc gaggtcagga
     7021 gatacgattg ttgtttggag attagataga ctaggacgga acatggagga tttaatcacg
     7081 ttagttaatg aacttaacga acgaggtgtg agttttcata gtttagaaga aaatataacg
     7141 atggataaat caagttctac aggacaatta ttatttcatt tattcgcagc atttgcagag
     7201 tttgaacgta atttaatttt agagcgatca tcagccggtc gaattgcagc acgtgctaga
     7261 ggccgatatg gaggtagacc tgaaaaatta aataaacaag atttaaactt acttaagaca
     7321 ctttatgata atggtacgcc aattaaaaca attgcagagc agtggcaagt ttcacgtaca
     7381 actatttatc gttatctcaa taaattagag gcaaaagaga ataaaaacaa gtagagcaac
     7441 taatctagct tactataatg aatctactaa ataattttat atatcattaa catacaaaga
     7501 ctttgattca atgtcactcg atgtaaaaga gacgttctga cagcgtctaa aatctcataa
     7561 tattttcctg ttatgagatt ttaataataa cacaagaaaa aagcgtacaa attcgtacgc
     7621 ttttttaata taatacctgt ttcactaatg aacgttttaa gtatcttcat cattaactga
     7681 aactacagta ataatactcg tcaacaatat tagtatagtt aaaatagaaa gacttaggac
     7741 tggcataacc gaactaaaat tatatttgaa atataaaagt gctaatgaag agagaaatgt
     7801 aaaaataata aataccaaag accatttttc taatttattc attggcttca cctctttgaa
     7861 cttttatata atcataggag atatttttac tacgatttat aaaaaataag aagataatca
     7921 ttattaaaga aacgattaat ataatgttga atcctatagt atcacctaat tcgtttacac
     7981 ctttgcctaa tatcggagat acaaagcttt gtattaataa tgaaagagat gcccatatag
     8041 taaatgaggt tctgttgcaa agttgaattt atagtataat tttaacaaaa aggagtcttc
     8101 tgtatgaact atttcagata taaacaattt aacaaggatg ttatcactgt agctgttggc
     8161 tactatctaa gatatgcatt gagttatcgt gatatatctg aaatattaag ggaacgtggt
     8221 gtaaacgttc atcattcaac ggtctaccgt tgggttcaag aatatgcccc aattttatat
     8281 caaatttgga agaaaaagca taaaaaagct tattacaaat ggcgtattga tgagacgtac
     8341 atcaaaataa aaggaaaatg gagctattta tatcgtgcca ttgatgcaga gggacataca
     8401 ttagatattt ggttgcgtaa gcaacgagat aatcattcag catatgcgtt tatcaaacgt
     8461 ctcattaaac aatttggtaa acctcaaaag gtaattacag atcaggcacc ttcaacgaag
     8521 gtagcaatgg ttaaagtaat taaagctttt aaacttaaac ctgactgcca ttgtacatcg
     8581 aaatatctga ataacctcat tgagcaagat caccgtcata ttaaagtaag aaagacaagg
     8641 tatcaaagta tcaatacagc aaagaatact ttaaaaggta ttgagtgtat ttacgctcta
     8701 tataaaaaga accgcaggtc tcttcagatc tacggatttt cgccatgcca cgaaattagc
     8761 atcatgctag caagttaagc gaacactgac atgataaatt agtggttagc tatatttttt
     8821 tactttgcaa cagaaccagc atttgtttta atatttgttc caaagagcca tcatggcttt
     8881 gacagagctc ttcttctatg caaatgcttt taatccgatc cacacgaaaa ttcctatatt
     8941 catttcttag cctgcaaaac cgattaagta ccagttctgt tcataaaacc ccagtgatat
     9001 aggctctatc attctgcttt ccggttcttg ccctcctgat gcaggatatt gaattgatat
     9061 taccctttta ttgcagattg cagtctgaat tgctgcaata acgttatccg ccaatgtatt
     9121 tttctgtcca gatgtgctgt acacgttaat actgttctcc aactcctgtg catagttttt
     9181 ttcaccatgc ttcaaaatag atttgatttt atacatagct gaatcaaaat cctttataaa
     9241 tgattcatct ccatggcaat ttaaaaattt ccctgctgta atcaatgcac ccacttccgc
     9301 cgctgtaaac attaccggcg gaagtaggaa gccctctaca agaaaatatc cttttccggc
     9361 ctcagatcca attggtattc cggcttcttc aagtgtccgg atatctctgt aaactgtcct
     9421 taagcttata ttaaatcgct gtgcaatttc tttggcagga attatttttt tgattgcagc
     9481 tgaataagaa tagaggttac tctgttaatc ctgttcaaat tttattcctc ctctgtgact
     9541 tccataaaaa gtatatccta tgcgttctta agctagctgc tgttagtgct tctcattgca
     9601 ccctggttat aaaagccata ctcacaaacc tcttcaccaa aactctttac atctctaata
     9661 tagaactcta tctagcgaac ttttagaaaa gatataaaac atcagagtat ggacagttgc
     9721 ggatgtactt cagaaaagat tagatgtcta aaaagcttgt agttaaagct ttttagacat
     9781 ctaaatctag gtactaaaac aattcatcca gtaaaatata atattttatt ttctcccaat
     9841 caggcttgat ccccagtaag tcaaaaaata gctcgacata ctgttcttcc ccgatatcct
     9901 ccctgatcga ccggacgcag aaggcaatgt cataccactt gtccgccctg ccgcttctcc
     9961 caagatcaat aaagccactt actttgccat ctttcacaaa gatgttgctg tctcccaggt
    10021 cgccgtggga aaagacaagt tcctcttcgg gcttttccgt ctttaaaaaa tcatacagct
    10081 cgcgcggatc tttaaatgga gtgtcttctt cccagttttc gcaatccaca tcggccagat
    10141 cgttattcag taagtaatcc aattcggcta agcggctgtc taagctattc gtatagggac
    10201 aatccgatat gtcgatggag tgaaagagcc tgatgcactc cgcatacagc tcgataatct
    10261 tttcagggct ttgttcatct tcatactctt ccgagcaaag gacgccatcg gcctcactca
    10321 tgagcagatt gctccagcca tcatgccgtt caaagtgcag gacctttgga acaggcagct
    10381 ttccttccag ccatagcatc atgtcctttt cccgttccac atcataggtg gtccctttat
    10441 accggctgtc cgtcattttt aaatataggt tttcattttc tcccaccagc ttatatacct
    10501 tagcaggaga cattccttcc gtatctttta cgcagcggta tttttcgatc agttttttca
    10561 attccggtga tattctcatt ttagccattt attatttcct tcctcttttc tacagtattt
    10621 aaagataccc caagaagcta attataacaa gacgaactcc aattcactgt tccttgcatt
    10681 ctaaaacctt aaataccaga aaacagcttt ttcaaagttg gcgtataaca tagtatcgac
    10741 ggagccgatt ttgaaaccac aattatgata gaatttacaa gctataaggt tattgtcctg
    10801 ggtttcaagc attagtccat gcaagttttt atgctttgcc cattctatag atatattgat
    10861 aagcgcgctg cctatgcctt gccccctgaa atccttacat acggcgatat cttctatata
    10921 agcgtaccgg ttccaatttt ttcgcagttt aacttttccg acgcatttat cgtcttggta
    10981 gtaaagatat attatcttat cagtattgtc aatatattca aggcaatctg cctcctcatc
    11041 ctcttcatcc tcttcgtctt ggtagctttt taaatatggc gcttcataga gtaattctgt
    11101 aaaggtccaa ttctcgtttt catacctcgg tataatctta cctatcacct caaatggttc
    11161 gctgggttta tcgatatctt tcaggtgccc tgctttcatt tctgtaatca ctgttcccgc
    11221 ctctcttcta tatcagcggc atatgtgcta tccaggcagc cggttttacc agtgtatttt
    11281 ttatacatgt ccctggtata ttttgttata ttcctatcat actccggata ggcataatga
    11341 agcctttccg ccacctcacc ggataccgcc ctgaacaatt gatggcatag aaataatgct
    11401 tcccatatgt tttcatagga atccatccgg taggtggaca aaagtttctc ccacaaatcc
    11461 tcggatatat acctttcaat aaacttatag ttcttgccta cacttcattt aaagcctgtt
    11521 tcgatgccga ccttccatga tatcattctc agcagctcat ggcgaacaat ctgattaaaa
    11581 tgatcaatag caaataaaat ttccttacgg cacaatcctt taataacata aggtgttaca
    11641 ttccaaaatt cattgcagca atcatcatac tcccttgcgc ttggctttct tacatgataa
    11701 tctatatcag tcggaactat gtccctttta attctacaat ctttatcaat tagaaccttt
    11761 attaatttat cgccctttag gtaattatct aactcttcca agggcaataa ggtaagatca
    11821 attttattgt aatcatcaaa tagctataat agatttagag gtaaagaaat taaatacatt
    11881 gaagagcaga aagattttac aaaagagtat tttaataaaa atgatggttc tgttgcaaag
    11941 taaaaaatat agctaatcac taatatatca tgtcagtgtt cgtttaactt gctagcatga
    12001 tgctaatttc gtggcatggg gaaaatccgt agatctgaag agacctacgg ttctttttat
    12061 atagagcgta aatacattca atacctttta aagtattctt tgccgtattg atactttgat
    12121 atcttgtctt tcttacttta atatgacggt gatcttgctc aatgaggtta ttcagatatt
    12181 tcgatgtaca atgacagtca ggtttaagtt taaaagcttt aattatttta gccattgctg
    12241 ccttcgttga aggtgcctga tctgtaacta ccttttgagg cttaccaaat tgtttaatga
    12301 gacgtttgat aaacgcatat gctgaatgat tatctcgttg cttacgcaac caaatatcta
    12361 atgtatgtcc ctctgtatca atggcacgat ataaatagct ccattttcct tttattttga
    12421 tatacgtctc atcaatacgc catttgtaat aagctttttt atgctttttc ttccaaattt
    12481 gatataaaat tggggcatat tcttgaaccc aacggtagat cgttgaatga tgaacgttta
    12541 caccacgttc tcttaatatt tcagatatat cacgatagct caatgcatat cttagatagt
    12601 agccaacggc tacagtgata acatccttgt taaattgttt atatctgaaa tagttcatac
    12661 agaagactcc tttttgttaa aattatatta taaattcaac tttgcaacag aacctcctaa
    12721 ctgtattacc accttaaaag tagttgcaga cgcacttcct aaatcgtcag cagtgtttaa
    12781 ccacatatca tcaacaataa tcatatgacc tgttgatgat actggagcaa attctgtcaa
    12841 cccttcaact acacctaaaa taaatgcttt aatctgctct ataaaaccca tttttctcct
    12901 ccttttaact tatatcagtt tttttaaagt atgagaataa tataattaca ctgaatatag
    12961 atgtaacaat tatgataatt aaagataata gaaatggata agtattaggt aatgttcctc
    13021 tagatatgtc tccaactgca gcccaaggaa ataatcctct atgttcagaa ttagcagtca
    13081 ttaaatttat caaagtaatt attatggtta aaacaattgt gggaacataa tttttaaaat
    13141 atatcgacaa aataattatt ggtggagata atatccataa taacactccg ccaataacaa
    13201 atgtaaagaa tgaatcaatt attaaactct ggcttaaccc ttgaaaatgc aatagcatac
    13261 ctagcattaa agttagcaac catgcaataa cagatagtgt ttgaatccac aagaataata
    13321 atattatttt acttactaaa aaactttctc tagatatagg tataattaat aagtttttta
    13381 aagtatcttc tatatattct cttccaaaca aataggctat tataacccca tatagaggag
    13441 gtccaataat tagcatatga tataaactga cttcttcaaa taactgttta aatacaatat
    13501 taggagtcgg tactttcgtc cgcatactaa caaaagaagc tacaaccacc ataaaaggtg
    13561 ctacgcatgt acctaaaata cttattagaa acatatatga tctttttaac ttaataaatt
    13621 ctgtacggag tagattatcc aattgtgcca cctcctacta agtcttcgaa ataagtttct
    13681 agattatctt ctatcactct catctggaaa acatcaatat tgtttaatac taataatcta
    13741 ttaatttctt gttgtctatc aatatgtgaa taaattttaa attcgccatt ttctttaatt
    13801 ttatagtcat aaattccgaa gttagtttcc aacaaacatg caactttttc ttcatctgat
    13861 actgatatac ttataaattg tctgttcttt ttttttaaat cttcatacat aatttcttct
    13921 aacaaaactc cgttatgaat aatacccacc ttgtctacta actgctctat ttctgacaat
    13981 atatgacttg aaattaaaat ggttatattt ctagattgag ccagatcctt aatcaacttt
    14041 ctaatttctt ttatgccaat aggatctaat ccattcgtcg gctcatcaag tatcaataat
    14101 tcgggattgt gcaataaagc tctcgcaatc cctaaacgtt gcttcatacc taaagaataa
    14161 tttttaaaca attttacttt ttcagaagct agtcctacta tttctaacac ttcttcaatt
    14221 gcattttctt tttgtatacc taatatttta gcatttatag ttaagttctc tttagctgtc
    14281 aaattactat aaaaacctgg cgtttcaacc atagcaccaa tattttttaa aatttcagtt
    14341 ttattacttt cgaactcttt ttcaaatatt ttaatattac ctttcgtagg tttaattaag
    14401 cctaaaagca ttcttatagt agttgttttg cctgcaccat ttcttcctaa aaaaccataa
    14461 atttgtccac tttcaacagt tatactcaaa ttattaactg ctatctgact tccatattgc
    14521 tttgttaagt tatttatttc aattatatta ttcaaatttt tcacctctgg cacctttctt
    14581 agtttgttgt tacctttatc ttacgcgcga ttagaaaagg ctgcctttat ctattcttac
    14641 aaaaacagcc gctaatctta caaaaatgaa agattggagt tatttaaatt gaatggtgaa
    14701 tattgaacca tcgtttaatg tagatgtagc acttacttta tggcctaagc gctttgagat
    14761 tgtgctgaca atatataaac caataccgct tgatttctca cttattctac cgttatagcc
    14821 cgagaaacct ttatcaaaga ttttcggtaa atcactcgca ttaatgccga taccgttatc
    14881 tcggattgat aatttctttg tattttcgtc aaacgtaatc cacacatctt tgccacgtgc
    14941 atattttaat gcattgttta atatttgctc aatcataatt gatgcccatt tggcatctgt
    15001 taatataacc gcttcacttt tctcataatg caactttgtt tgatgatgaa taaactgtat
    15061 cgcataacgt ttaatcagtg gtcgaattaa ttcatctaca ctcacttcca taaagaccat
    15121 gtatgtcttt tggttcatga gtttcaaata gttcagtgca agattcgtgt aattatcaat
    15181 ttgtaagact tcattacgca cgttagaaat cacgtgttca tcaggatctt caagcagtaa
    15241 ctttgatgct gtaatcggtg tcttgatttg atgcacccac attaaaaaat atgactctaa
    15301 ctcactttgg tagttaataa agtcattacg aagtttatgg ttttcgattc ttaaatcttc
    15361 gttctgttcc tgtagtgttt attctttttt aaagttcatg taatggatac cccagtaaat
    15421 cattgaaaca aacaatacaa tacctagacc aatcatatat gcttgcatcg gcacattata
    15481 catgaataat ataaagtaga ataaagcaca agtaaggatg acaatataaa tttcacgttg
    15541 gattgatttc aagaaattca tacgtcacct acacgatatc cgacattttt cttcgtttcg
    15601 ataaaatctg taagtcctag tttttgtagc tttttgcgta aacgtgtaat gttgacagca
    15661 agcgtattgt catcaatgaa gtgttctgat tcccagcatt tttcgattaa cgcattacga
    15721 ctgacgaatt tgcccttgtt ctggaataag ctatgcatga tttgcaattc agtgtgtgtc
    15781 aggtctatgg tttcttcatt aaatttaagc tttgctgcat caagtagtaa ctcgcaatca
    15841 tctactgtta aattattaac ttgagtggtg aaatcatacg tgcggcgtaa tagtgcttga
    15901 atcttagtaa ttgtaacagt catattaaat ggctggttct gttgcaaagt aaaaaatata
    15961 gctaatcact aatatatcat gtcagtgttc gtttaacttg ctagcatgat gctaatttcg
    16021 tggcatgggg aaaatccgta gatctgaaga gacctacggt tctttttata tagagcgtaa
    16081 atacattcaa taccttttaa agtattcttt gccgtattga tactttgata tcttgtcttt
    16141 cttactttaa tatgacggtg atcttgctca atgaggttat tcagatattt cgatgtacaa
    16201 tgacagtcag gtttaagttt aaaagcttta attattttag ccattgctgc cttcgttgaa
    16261 ggtgcctgat ctgtaactac cttttgaggc ttaccaaatt gtttaatgag acgtttgata
    16321 aacgcatatg ctgaatgatt atctcgttgc ttacgcaacc aaatatctaa tgtatgtccc
    16381 tctgtatcaa tggcacgata taaatagctc cattttcctt ttattttgat atacgtctca
    16441 tcaatacgcc atttgtaata agctttttta tgctttttct tccaaatttg atataaaatt
    16501 ggggcatatt cttgaaccca acggtagatc gttgaatgat gaacgtttac accacgttct
    16561 cttaatattt cagatatatc acgatagctc aatgcatatc ttagatagta gccaacggct
    16621 acagtgataa catccttgtt aaattgttta tatctgaaat agttcataca gaagactcct
    16681 ttttgttaaa attatattat aaattcaact ttgcaacaga accgtatttt atgagtacac
    16741 tctaaattaa ggagatgtat aatcaatcta aaattgtatt tttatacttt tgttatataa
    16801 tctttctact tagagatata ttgtaaaaaa accaacaaaa tgttatatta acattactat
    16861 tttatcgatg aaggaggatt aaaatgacag cttctatgag actcaaataa acctttttga
    16921 atacaaaact aaattaattc aaaaaggctt gtccgcaata cacactcata ggatgactta
    16981 tgtcattttt tatccttcga taggaataat aaacgctttc aaatactaaa acatcataat
    17041 aaatttttaa gtgtttgaaa gtgtaatgtg aatgagacgg gagtagcctg tctcattttt
    17101 ttgcgtacac gtcctttaaa tatacaagga gtgtataaat atggaacaat atacaattaa
    17161 atttaaccaa atcaatcata aattgacaga tttacgatca cttaacatcg gtcatcttta
    17221 cgcttaccaa tttgaaaaaa tagcacttat tgggggtaat ggtactggca aaaccacatt
    17281 actaaatatg attgctcaaa aaacaaaacc agaatctgga acagttgaaa cggttggcga
    17341 aattcaatat tttgaacagc ttaacatgga tgtggaaaat gattttaaca cgttagacgg
    17401 tagtttaatg agtgaactcc atatacctat gcatacaacc gacagtatga gtggtggtga
    17461 aaaagcaaaa tataaattag ctaatgtcat atcaaattat agtccgatat tacttttaga
    17521 tgaacctaca aatcacttgg ataaaattgg taaagattat ctgaaaaata ttttaaaata
    17581 ttactatggt actttaatta tagtaagtca tgatagagca cttatagacc aaattgctga
    17641 cacaatttgg gatatacaag aagatggcac aataagagtg tttaaaggta attacacaca
    17701 gtatcaaaat caatatgaac aagaacagtt agaacaacaa cgtcaatatg aacagtatat
    17761 aagtgaaaaa caaagattgt cccaagccag taaagctaaa cgaaatcaag cgcaacaaat
    17821 ggcacaagca tcatcaaaac aaaaaaacaa aagtatagca ccagatcgtt taagtgcatc
    17881 aaaacaaaaa ggcacggttg agaaggctgc tcaaaaacaa gctaagcata ttgaaaaaag
    17941 aatggaacat ttggaagaag ttgaaaaacc acaaagttat catgaattca atttcccaca
    18001 aaataaaatt tatgatatcc ataataatta tccaatcatt gcacaaaatc taacattggt
    18061 taaaggaagt caaaaactgc taacacaagt acgattccaa ataccatatg gcaaaaatat
    18121 agcgctcgta ggtgcaaatg gtgtaggtaa gacaacttta cttgaagcta tttaccacca
    18181 aatagaggga attgattgtt ctcctaaagt gcaaatggca tactatcgtc aacttgctta
    18241 tgaagacatg cgtgacgttt cattattgca atatttaatg gatgaaacgg attcatcaga
    18301 atcattcagt agagctattt taaataactt gggtttaaat gaagcacttg atcgttcttg
    18361 taatgttttg agtggtgggg aaagaacgaa attatcgtta gcagtattat tttcaacgaa
    18421 agcgaatatg ttaattttgg atgaaccaac taatttttta gatattaaaa cattagaagc
    18481 attagaaatg tttatgaata aatatcctgg aatcattttg tttacatcac atgatacaag
    18541 gtttgttaaa catgtatcag ataaaaaatg ggaattaaca ggacaatctc ttcatgatat
    18601 aacttaaaaa ctatacacta atttatattg aatattaggt tcatttatat caatataaaa
    18661 aatacgttca caagaaaaat ataatagaaa taaggatcca ataaaatgac tcgacataat
    18721 gaaattatta aatgtgcaga aaaatatcaa ttacacatcc aacctcaaac aatctcattg
    18781 aatgaatcgg gacttgattt tcaagttgca tttggaaaag ataaacatgg agtagaatgg
    18841 gttttgagac taccaagaag acctgacgtt tataaacgaa caaaacccga aaaacaaacg
    18901 gtagacttct tacagaagaa tgtttcattt gaaataccga agtggaaagt acatgcaaaa
    18961 gaccttattg cttacccaaa acttacaggt aaacccgcag ccacaataga tccagaaata
    19021 caaaattatg tatgggaaat tgaacacaaa ccattaccag aaaactttat taacacatta
    19081 gctgaaacac tcgtagattt acacaacata ccagaagaaa acattaacgt tcagcatata
    19141 aatatcaaaa ccatacaaga aataaaaaat gactttcaaa gaagaatgaa taaagttaaa
    19201 gaaacttatg gcgtatcaga tgaattatgg aacagatgga aacaatggtt agaaaacgac
    19261 gaactatggc ctcgacatgc gaccatgata catggggact tacatccagg acatataatg
    19321 gtagataacc aagcaaacgt cacaggtctc atagactgga ctgaagcaac ccactccgac
    19381 ccatcaatgg actttatagg acaccatcgt gtattcgacg acgaaggatt agagcaactt
    19441 ataacagcat acggtaaagc tggaggtgaa atatggccac gaatgaaaga gcatataata
    19501 gaactcaatg cagtattccc aatgtttatc gctgagtttg ctatggaatc aggagaatcg
    19561 gcgtatgaaa cgatggcatt gaaagagtta ggtatgaaag agtagaactt atattaaaag
    19621 aggcccattt taaagacgaa ggcaatcctg atgaaatttt aaaactgcgt ttaattagtg
    19681 atggtctttg gttttctata atgtattaaa tatctggaca tggaacaaat gcaacaaatg
    19741 gaaagaatcg ttttcgaaat ttctaactcc ttaaatcagg aggataaata aacggtcatt
    19801 ttcattgaaa gcacttatat aaatttcatc aattttaata cctaccgtaa atacatttca
    19861 taagtattaa acagatgatt aaaattttta gttaatttaa atatttatga tagagatgac
    19921 cttcaaatga acgtttataa cgcaatcatg atgagagtat taatacagtt aattatttga
    19981 aatactttag tttacataat cgatgattac cagaagttct cactatataa aagacactaa
    20041 aattttataa cttttagtgc ctaatcaatt attttagcta ccaaacaaac gactccaaaa
    20101 ccccttttta ggttccgttt cttcactctt ttcttctata tcactatcat tgtcatttag
    20161 attagctgga acgtcttctt tttttgcttc ttcaccttgt gtactttcgt cgctttgact
    20221 tccagatata tccttatatt gaatctctgt ttctttagtt tcttcctgat ctctgttaat
    20281 atttacagga ttagtagtat atgttttttc ttgtgcatca acgttttgtc tagtgttagt
    20341 agatgtatca aagggataat taaggtgttt ttctttttct aattgatttt ctaatttttg
    20401 aatcttttta ttactctcta atgccagaac ttgctgattt tcaagcaatt ttgatctttc
    20461 ttgcaactct tttctgtaaa attcaattgt tgtttcatga cgactttctt gtttttcaat
    20521 ttgattattt aaagtatcaa tctgattttt aaggatttct actatttgag catcgctttt
    20581 cgattcaaaa ttaatattat ccgacccttt tttttgtttg tcttcagtag tactttcaaa
    20641 accatatttc tttttatttt catttactct ttgaatgatt ttttctatat cggtatcttc
    20701 tttaataaac gaagtgtttt cctgttttat tgtctctata ttcaatcgct taatattatt
    20761 aaaaatcgtt tgcttactaa cccctaattc ttcactcaac tttttcacac ttttcatatc
    20821 atcaaccctt tataaaatgt ttataaaccc ttgataaaat attataagct tataatgctt
    20881 aataataaag tgattaataa ataaaaataa acatccatca acctttttat caagggttta
    20941 tgaaaggttt atgatattta tcaagggttt ataaaccctt gataaagcta tattttccct
    21001 tttataagtt tatttaaagt gctataataa acttaatata acaaaaaccc caactactgg
    21061 taatagtcgg ggtttggtaa taaaacgttt agaaactgtt tatttatata attttcgata
    21121 cttgtattat ataatgaata atatcttagt gcaagcacct aaatcattaa ataaatgtaa
    21181 agctaaataa aaacgtttta ttacctctta ccaaactaaa atatggaaag aggttttttg
    21241 tcatgcaaaa tcaatatttt acagtgcaag aaaattacaa agaaagattt tatcaaatcc
    21301 ctaaagtatt ctttaccagt gaaaattata aaaatctaac taatgatatg aaaatagcct
    21361 atgctatctt acgtgatcgc ttaaatttat ctattaaaaa tagctgggtt gatgaagatg
    21421 gtaacattta ctttgtttat tcaaatgaaa agctaatgga aatcttaaat tgtaaaaaag
    21481 aaaagttaac aaaaataaaa aaagggttag aaaacgatgg tctactcatt caaaaacgac
    21541 gtggtttaaa taaaccaaat attctatatt taatgaaacc tattgtcaca gaacgtgata
    21601 tttacaaaat agaaaaagaa gaaaacgatg ttgaacctta cggcgagaag gaagttcgaa
    21661 aatcgaacgt ccagaagttc gaaaatcgaa cgtccagaag ttcgaaaatc gaacgtccag
    21721 aagttcgaaa atcgaacact aatgatactg actttaatga cattgacttt aatgatactg
    21781 agaataatga tatgaatgac ttgaatgata taaagtacaa aaatgaaatt agtaatcatt
    21841 caaatcattc aaatcaattt acacataatt ttgatgataa agaaatgcta ttgcaagaat
    21901 tcccagaaca actaactaat tatttattaa aatatgatta tagagattta gaaatcataa
    21961 aggctgttat tcttaaagca aaaaaatcat ttaattcaag gcatgaagat atgcattaca
    22021 tgttagagga cattgaggat gaaatattaa cttctttaaa aagacttaaa aaagctatac
    22081 atgatagggg agttaaaggc caaaaggaaa caatcaagtc aatgcaagct tatttaatgc
    22141 aaacaattct aactgaactt gaagaaacac atgcccttta tatgcgccgt aaaaacatga
    22201 aacaatataa tatctttaat caataattca aatgatttta taacactcga agagacatca
    22261 aaatattccg ttaaatcatc tgacttttta actgatgacg acgaaaaaaa tcaagaaatt
    22321 gtaagtgatt tagaaaaagg tttgtatcga aaacgtatgt taagttatgg tggattgctt
    22381 aaacaaaagc ataaaatttt aaacttagac gatgccgaag atggtaattt gattaataca
    22441 agtgatgaag ataaaacgac agacgaagaa aaaaagcaca ttcaattacc gcaatttgga
    22501 atttcgaaaa gcaaaattat tatttaagac attagtgata actgatgtct ttttttattg
    22561 tttttctgta aaaaagtgct gtcttatttt tgtgacaaat gctgtatgta gtgtcacaaa
    22621 agtgtgacac tacagctttg tatgatatca ctttaaaata acttaaaacc cttggaatgt
    22681 ctggccttgc cagatctatc atttttgaat gatagcaaat ttcccttatg ctcttacgga
    22741 gattttagag ttaaattaaa atttctaagt ttttgataag aaaagccctg caggaattta
    22801 gaaaaacatg gggaagtttt aaagtatttt atgctaattt ttaaatttgc atgtaaatgg
    22861 gcagtatcta aaaaattagt cactgatttt gctgaaattt ttgtttgtga aattagcata
    22921 tatttatttg gctcatattt gcgttttaag agactgtata gatttttaag tacaaaacct
    22981 atatgatttg cctctaagtc ttcaaaatgc ctcttaaaat ccaaaataaa agtgtttaat
    23041 attgtaataa ggattgctat ttttataaaa ggagagatat catgaagatt aaaactttcg
    23101 ctacttttac tcatcgtcaa ttagataaac aagttaatag gtttttaaag aatgatattc
    23161 atgtattaga aattcaaaca cacagtaatt ggttatatat ttcagctatt gttttttatg
    23221 aggataaata aggaacatcg tatttatgcc gaaaaaattt attgatgttg agaagaaccc
    23281 ttaactaaac ttgcagacga atgtcggcat agcgtgagct attaagccga ccattcgaca
    23341 agttttggga ttgttaaggg ttccgaggct caacgtcaat aaaacaattg gaataaaatc
    23401 aacctacaga gcatccagct gcaaatgcag ttccgcaaac tgcttcacat acaccgccgg
    23461 ctattggatt tacgattgcc catactccac agtagtgagc acatgcataa agtccagcca
    23521 tactacaagc gaatgctttg ccgttccatt tgaatcctgc atatgttacc ggtctgtttt
    23581 tatcaacttt ttcagcctta tattcaacgt aatttttgtt aataagtatt tttccctctt
    23641 tgttttcagt catacttctt ttttcggcaa tgaattttgt gatttttttg ttgtagttat
    23701 catatattgt ttcagaaact acaatttctt ttgttttttc atttttataa gcgttattag
    23761 ctatgtagcc atatgcattt ttatcatttg cttctgtagc tagatatttt aatttagaat
    23821 ttttgtcttc tagctttatt tttttaaatc cttctttttt catttgcttt tcgaattttt
    23881 gcatatcttc atttttattt tgcaattgtt ctagaaaact tatttctttc ttggtcattt
    23941 gtgatacttc gatgtttttg cttttcaatt tttctttttg attttctagt aaagaacttt
    24001 tttgttcttc atttgcgtaa gcattagaaa aattcgcgct aaataccagt aggaacaagg
    24061 aaattattga aaataatttt ataattttca tttgatacct ccaagataat aagatatttt
    24121 aattgtataa gtaagcgctt tataaaatca atatttattt taatatattt ataaacatat
    24181 ttttgaaagg agtctatttt atgaatgaaa atttagaaaa atatataaaa agtttgccac
    24241 ttttaggttt gttaattagt attttgttag ttgttttatt cttttttatt ttagatgttg
    24301 atgaagattt attcgtggtt tttttatact gtttattgcc tttgatagtt aatttgtcta
    24361 tttatggttt ttatgttttt gttaaaagaa agtaagatta tgaataattt tgtttttaat
    24421 ttgtatgctt tgagggggtt ggaaaacggt aggtgtatag attagatttc ttgttttttt
    24481 gaaacgagtg tgaacgagtt tcttcttgtc ttgatttttg ataaaaacgc cctacaggaa
    24541 tttagaaaaa cgtggggaag ttttaaagaa ttttatgcta atttttaatt tgcatgtaaa
    24601 tgggcagtgt ctaaaaatag ttattgtttt tgctcaaatt tttgtttttg aaaatagcat
    24661 atatttattt ggctcatatt tgcgttttaa aagcatatat aagttttaga tataaaacta
    24721 tatgaatcac ccctaaatct ttaaaatgcc ctcttaaaat tcaaaataag ggcataaaaa
    24781 ataaaagcta ccccagataa agtgaggtag ctttttcttt catacggtct atttattttt
    24841 ctttcgacgc cgtatcgtcg atgtaattca aaaaagttat gggctataaa tctacatcac
    24901 tttttcaaga atgtagtagc aatattcaac gcaaattaat ttttataact gctcggaata
    24961 tctcaagccg tttctttaat tttgaaataa aaaaatcgac gaaggtcgat tacgtttttg
    25021 cacatgtcga tttatccgac gtataagtgc gcccttacgg gatttaacta gattataacg
    25081 acgaatttta gacctgtaaa gcaataacaa ttaggtctac caggtagata aagtgtacaa
    25141 agtagaaccg aaaaagttat ttattttgaa gatttttcgt agatataatt tgctaataaa
    25201 cttcctaaaa ctgaataaag aaaaatagtt aaactcatgt aatcactcca taattctgaa
    25261 gtgtctccat gtctacgcat agacacgcat ttatgccgaa aaaatttatt gatgttgaga
    25321 agaaccctta actaaacttg cagacgaatg tcggcatagc gtgagctatt aagccgacca
    25381 ttcgacaagt tttgggattg ttaagggttc cgaggctcaa cgtcaataaa
//
