LOCUS       NZ_CP113030            17850 bp    DNA     linear   CON 14-JAN-2024
DEFINITION  Staphylococcus aureus strain Akali plasmid unnamed4.
ACCESSION   NZ_CP113030
VERSION     NZ_CP113030.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN31523637
            Assembly: GCF_026625365.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 17850)
  AUTHORS   Huang,Y.-T. and Liu,P.-Y.
  TITLE     Whole genome sequencing of methicillin-resistant Staphylococcus
            aureus
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 17850)
  AUTHORS   Huang,Y.-T. and Liu,P.-Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-OCT-2022) Computer Science and Information
            Engineering, National Chung Cheng University, No.168, Sec. 1,
            University Rd., Min-Hsiung Township, Chia-yi County 621, Taiwan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: flye v. 2.8.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 306x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/14/2024 03:23:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,092
            Genes (coding)                    :: 2,979
            CDSs (with protein)               :: 2,979
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 113
            CDSs (without protein)            :: 113
            Pseudo Genes (ambiguous residues) :: 0 of 113
            Pseudo Genes (frameshifted)       :: 59 of 113
            Pseudo Genes (incomplete)         :: 51 of 113
            Pseudo Genes (internal stop)      :: 23 of 113
            Pseudo Genes (multiple problems)  :: 19 of 113
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP113030.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..17850
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="Akali"
                     /isolation_source="environmental"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed4"
                     /geo_loc_name="Taiwan"
                     /lat_lon="24.23321 N 120.9417 E"
                     /collection_date="2022-06-01"
                     /collected_by="Po-Yu Liu"
     gene            complement(<1..550)
                     /locus_tag="OS080_RS00005"
     CDS             complement(<1..550)
                     /locus_tag="OS080_RS00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_204180552.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSI"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(787..882)
                     /locus_tag="OS080_RS00010"
     CDS             complement(787..882)
                     /locus_tag="OS080_RS00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_000889979.1"
                     /translation="MLEILVHITTTVISGCIVALFTHWLRNRNDK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(1360..1968)
                     /locus_tag="OS080_RS00015"
     CDS             complement(1360..1968)
                     /locus_tag="OS080_RS00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017432088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000793183.1"
                     /translation="MKNLKSFFIKNTLVLTSTALLFSSFEPVVHAAENKEVVKTVENDN
                     VEFNELLEGQEYIWEVLSRDDEGFKMFLDEQRAFNPNFDNDVLLAKQEGALNSSVFANN
                     SMTLNSNKPTPRGPIGATLKAIKALSPSLRHGGTAISWIIKPLSRKHAVLVKKYSRKMS
                     NAIDRLDKSTKSAVENAFVKAGIPRSDAKTLTYIVFLVI"
                     /name="hypothetical protein"
     gene            complement(3475..>3579)
                     /locus_tag="OS080_RS15850"
                     /pseudo=""
     CDS             complement(3475..>3579)
                     /locus_tag="OS080_RS15850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     gene            complement(3639..4313)
                     /locus_tag="OS080_RS00020"
     CDS             complement(3639..4313)
                     /locus_tag="OS080_RS00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISSau6 family transposase"
                     /protein_id="WP_001105943.1"
                     /translation="MNYFRYKQFDKDVITVAVGYYLRYALSYRDISEILRERGIYVHHS
                     TIYRWVQEYAPILYQIWKKKNKQAYYKWHIDETYIKIKGQWNYLYRAIDADGHTLDISL
                     RKKRDNHSAYTFIKRLIKQFGKPQMIITNQAPSTKVAMSKVIKDFKLTPNCHCNSKYLN
                     NLIEQDHRHIKVRKISYQSINTAKNTIKGIECIYGLYKKNRRFLQIYGFSPCRVISIML
                     AS"
                     /name="IS6-like element ISSau6 family transposase"
     gene            4350..5261
                     /locus_tag="OS080_RS00025"
     CDS             4350..5261
                     /locus_tag="OS080_RS00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="WP_078056064.1"
                     /translation="MSNFATEPNVSYADILEILKIKKAYNVKQCGNVLEFKPTDEGYLK
                     LHKTWFCKSKLCPVCNWRRAMKNSYQAQKVIEEVIKEKPKARWLFLTLSTKNAIDGDTL
                     EQSLKHLTKAFDRLSRYKKVKQNLVGFMRSTEVTVNKNDGNYNQHMHVLLCVENAYFRK
                     KENYITQEEWVNLWQKALQVDYRPVVNIKAIKPNQKGDKDIESAIKETSKYSVKSSDFL
                     TDDDEKNQEIVSDLEKGLYRKRMLSYGGLLKQKHKILNLDDAEDGNLINTSDEDKITDE
                     EAKAHSITAIWNFEKQNYYLRH"
                     /name="protein rep"
     gene            <6167..6268
                     /locus_tag="OS080_RS00030"
                     /pseudo=""
     CDS             <6167..6268
                     /locus_tag="OS080_RS00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            complement(6303..6443)
                     /locus_tag="OS080_RS00035"
     CDS             complement(6303..6443)
                     /locus_tag="OS080_RS00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001199886.1"
                     /translation="MQYNTTRSITENQDNKTLKDMTKSGKQRPWREKKIDNVRFCCKVK
                     K"
                     /name="hypothetical protein"
     gene            complement(6634..6981)
                     /locus_tag="OS080_RS00040"
     CDS             complement(6634..6981)
                     /locus_tag="OS080_RS00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119692.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDGI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(7000..7616)
                     /gene="cadD"
                     /locus_tag="OS080_RS00045"
                     /pseudo=""
     CDS             complement(7000..7616)
                     /gene="cadD"
                     /locus_tag="OS080_RS00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium resistance transporter CadD"
                     /name="cadD"
     gene            complement(7797..7919)
                     /locus_tag="OS080_RS00050"
     CDS             complement(7797..7919)
                     /locus_tag="OS080_RS00050"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466482.1"
                     /translation="MFFYEDDDFDEMEEKYDYHEDKKIDDAFMPRKFIDVEKNP"
                     /name="hypothetical protein"
     gene            complement(8000..8188)
                     /locus_tag="OS080_RS00055"
     CDS             complement(8000..8188)
                     /locus_tag="OS080_RS00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001030803.1"
                     /translation="MNKDTMLDKGYVIATILNVFFLLGLIFISHLENLYILIPYVILMG
                     INAIYLVVKVMNFKKNN"
                     /name="hypothetical protein"
     gene            complement(8768..8914)
                     /locus_tag="OS080_RS00060"
     CDS             complement(8768..8914)
                     /locus_tag="OS080_RS00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001092934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001092935.1"
                     /translation="MNTKILTGMTGSSLERKINNFINDNQIEVIDIKFSSSVFYFGVMI
                     IYK"
                     /name="hypothetical protein"
     gene            complement(8919..9122)
                     /locus_tag="OS080_RS00065"
     CDS             complement(8919..9122)
                     /locus_tag="OS080_RS00065"
                     /inference="COORDINATES: protein motif:HMM:NF013603.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="WP_001796115.1"
                     /translation="MYRKRMLSYGGLLKEKHKILNLDDAEDGNLINTSDEDKTTDEEEK
                     AHSITAIWNFEKQNYYLKNLRS"
                     /name="protein rep"
     gene            complement(9237..10181)
                     /locus_tag="OS080_RS00070"
     CDS             complement(9237..10181)
                     /locus_tag="OS080_RS00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001132442.1"
                     /translation="MPNFEKYNLSQVKTERFYQLPKYLFEDAYFKKMSAEAKIMYALLK
                     DRFELSIQNEWVDRNNNIYFIFSNKHLCEYLGYGEQKIIKLKKELVNFNLLTQERVGLN
                     KPNRLYLLKPNYDIEASLTKELPNSQFQNNEFGSSRTVNLSGQELPNSQSNDTELNNTN
                     YIENEDNDTYDMNDIISNTLINNNHHSNHTNHQKTEFNNDALKFQVLEELPQQLQDYLS
                     KFEIREIRIIKSVLLKGKKSFNTSHDTYYRLEDVEFEIVSVLKRFKAMLLQKNETVEAM
                     QGYLMQSIKAELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            10625..11395
                     /locus_tag="OS080_RS00075"
     CDS             10625..11395
                     /locus_tag="OS080_RS00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000848988.1"
                     /translation="MKTIKMVADELNVTKQTIVNNAKNLNISFKKENGINYINDNDCLK
                     IIEKITKKERTMQNKESIKKERFNENTAEFEKHIYNNSNGFESLKTKVNELEKQIEIFE
                     TRAKNDEKYIENLTKQLDQQNSNVNTLNKLLENQQILALESNKKIQKLENQLEEERQLN
                     YSFDTATNDRQSINPQEATFTEEYQNSNQQQKKIQPIEAELNHKGITKAKKDDSSNEDV
                     LKRDDKLSEEIESGPEDREVETPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(11711..12271)
                     /locus_tag="OS080_RS00080"
     CDS             complement(11711..12271)
                     /locus_tag="OS080_RS00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001077893.1"
                     /translation="MNRADIFKIFDVELNITIFLGALVATFIYFISYMNNVNELITLCL
                     TLAFPAYLLKISRSFEVILLEEKIKNSKIKICDKDRIEREILVKKNLIDELLFPNRVIK
                     KYTLTILIYSIGIIILLLLCNMLSYGIGENVNFIWRLLACYVTSVTVIIVALIIMIMIF
                     DLIIGLLLNFQIFLKNKKYDDFL"
                     /name="hypothetical protein"
     gene            complement(12476..14020)
                     /gene="qac"
                     /locus_tag="OS080_RS00085"
     CDS             complement(12476..14020)
                     /gene="qac"
                     /locus_tag="OS080_RS00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QacA/B family quaternary ammonium compound efflux
                     MFS transporter"
                     /protein_id="WP_000622774.1"
                     /translation="MISFFTKTTDMMTSKKRWTALVVLAVSLFVVTMDMTILIMALPEL
                     VRELEPSGTQQLWIVDIYSLVLAGFIIPLSAFADKWGRKKALLTGFALFGLVSLAIFFA
                     ESAEFVIAIRFLLGIAGALIMPTTLSMIRVIFENPKERATALAVWSIASSIGAVFGPII
                     GGALLEQFSWHSAFLINVPFAIIAVVAGLFLLPESKLSKEKSHSWDIPSTILSIAGMIG
                     LVWSIKEFSKEGLADIIPWVVIVLAITMIVIFVKRNLSSSDPMLDVRLFKKRSFSAGTI
                     AAFMTMFAMASVLLLASQWLQVVEELSPFKAGLYLLPMAIGDMVFAPIAPGLAARFGPK
                     IVLPSGIGIAAIGMFIMYFFGHPLSYSIMALALILVGAGMASLAVASALIMLETPTSKA
                     GNAAAVEESMYDLGNVFGVAVLGSLSSMLYRVFLDISSFSSKGIVGDLAHVAEESVVGA
                     VEVAKATGIKQLANEAVTSFNDAFVATALVGGIIMIIISIVVYLLIPKSLDITKQK"
                     /name="qac"
     gene            14198..14764
                     /gene="qacR"
                     /locus_tag="OS080_RS00090"
     ARG             14199..14761
                     /name="qacR"
                     /gene="qacR"
                     /gene_name="multidrug-binding transcriptional regulator
                     QacR"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(14897..15082)
                     /locus_tag="OS080_RS00095"
     CDS             complement(14897..15082)
                     /locus_tag="OS080_RS00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(15087..15425)
                     /locus_tag="OS080_RS00100"
     CDS             complement(15087..15425)
                     /locus_tag="OS080_RS00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            complement(15671..16279)
                     /locus_tag="OS080_RS00105"
     CDS             complement(15671..16279)
                     /locus_tag="OS080_RS00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            complement(16405..16983)
                     /locus_tag="OS080_RS00110"
     CDS             complement(16405..16983)
                     /locus_tag="OS080_RS00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690625.1"
                     /translation="MKIGYARVSTGLQNLNLQEDQLNQYGCEKIFSDHISGSKSKRPGL
                     DKAIEFARAGDTIVVWRLDRLGRNMEDLITLVNELNNRGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLKLLKTLYDNGTPI
                     KTIAEQWKVSRTTIYRYLNRLNNQENKDK"
                     /name="recombinase family protein"
     gene            17355..17723
                     /gene="cadC"
                     /locus_tag="OS080_RS00115"
     ARG             17356..17720
                     /name="cadC"
                     /gene="cadC"
                     /gene_name="Cd(II)/Pb(II)/Zn(II)-sensing metalloregulatory
                     transcriptional repressor CadC"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM/LEAD/ZINC"
                     /identity="100.0"
                     /coverage="100.0"
     gene            17716..>17850
                     /locus_tag="OS080_RS00120"
     CDS             17716..>17850
                     /locus_tag="OS080_RS00120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003267.1"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-associated domain-containing protein"
                     /protein_id="WP_267841428.1"
                     /translation="MSEQKVKLMEEEMNVYRVQGFTCANCAGKFEKNVKKIPGVQDAKV
                     "
                     /name="heavy metal-associated domain-containing protein"
     ARG             complement(12480..14020)
                     /name="qacA"
                     /gene="qacA"
                     /gene_name="quaternary ammonium compound efflux MFS
                     transporter QacA"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="99.81"
                     /coverage="100.0"
     Typing          5351..5488
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="99.281"
                     /coverage="93.0"
                     /evalue="1.01e-64"
     Typing          4374..5261
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="96.625"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(8930..9107)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.179"
                     /coverage="95.0"
                     /evalue="3.73e-65"
     Typing          complement(9238..10181)
                     /name="rep_cluster_1215"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.577"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tgatactttg ataccttgtc tttcttactt taatatgacg gtgatcttgc tcaatgaggt
       61 tattcagata tttcgatgta caatgacagt caggtttaag tttaaaagct ttaattactt
      121 tagccattgc taccttcgtt gaaggtgcct gatctgtaat taccttttga ggtttaccaa
      181 attgtttaat gagacgtttg ataaacgcat atgctgaatg attatctcgt tgcttacgca
      241 accaaatatc taatgtatgt ccctctgcat caatggcacg atataaatag ctccattttc
      301 cttttatttt gatgtacgtc tcatcaatac gccatttgta ataagctttt ttatgctttt
      361 tcttccaaat ttgatacaaa attggggcat attcttgaac ccaacggtag accgttgaat
      421 gatgaacgtt tacaccacgt tcccttaata tttcagatat atcacgataa ctcaatgcat
      481 atcttagata gtagccaacg gctacagtga taacatcctt gttaaattgt ttatatctga
      541 aatagttcat acagaagact cctttttgtt aaaattatac tataaattca actttgcaac
      601 agaatctttt atagtatcaa agaaaattaa taattctaat tatagagtta cacttacgtt
      661 tcttatgttt ttgcattcct ctactaacca gtgttataat atgattaaca agaattctag
      721 cgtgaataca ccaatcccct cactattgcc gtagtgaggg gattttttag gtgtgactat
      781 agtcgcctat ttatcgttgc gattgcgtag ccaatgcgta aataacgcaa caatacaacc
      841 actgatgact gtggtcgtga tgtgaacaag aatttctagc atgaataaca cctcctctct
      901 gcgtctaaat ttgacgcctg agagataggc gactctatta ttataccatc tgtgaatata
      961 caagcatatc tacttccgat aagtcgtctt atgttatata acttcgtttt ttatagtatc
     1021 aagacaaaag aagaaacgca gttcaaaatc atcacctaaa ttcattaatc taaagaaaaa
     1081 acggtgtaat aaatagtgaa tattatagtc tattaaagaa tagatttaaa aacactctaa
     1141 aaggtgcatt aaagatttgt aaaactttaa tatatccttt ttaggtgaaa acttatgata
     1201 attgtaggtt ctctcattat ctatgattat taattttaac tgtatctaga aaatcatcac
     1261 cccaatcaca aattgaaaat actactttat caagataaga aaaaagaaaa aaacttgccc
     1321 taagatttta taaaatctta gggcaagtca gctcaatatc taaataacta aaaatacaat
     1381 ataagttaaa gttttcgcat cacttcttgg tatacctgct ttaacaaaag cattttcaac
     1441 agctgatttc gtagacttat ctaacctatc aattgcatta gacatctttc ttgaatattt
     1501 ttttactaga acagcatgtt ttctacttaa tggtttaatg atccaagata tagcagttcc
     1561 accatgtctc aaagaaggtg atagagcctt aatagctttt aaagttgcac cgataggacc
     1621 tctaggagta ggcttatttg agtttaaagt catagaatta ttagcaaata ctgaagaatt
     1681 taaagcacct tcttgttttg ctagtaaaac atcattatca aaattaggat taaaagctct
     1741 ttgctcatct agaaacattt taaatccttc atcatctcta gataaaactt cccaaatata
     1801 ttcttgtcct tctaacaatt cattgaattc tacattatca ttttctactg ttttaacaac
     1861 ttccttattt tctgcagcat gaactacagg ttcaaaacta gaaaataata atgcagtaga
     1921 tgttagtacc aaagtatttt taataaaaaa actttttaaa ttcttcatat gacttttatc
     1981 ctccaattat aaatgttaaa attttttatt attaaatatt atatacataa aaggaattaa
     2041 attattatga aaaaagtaaa caaagagtac ttattgaact ttataattgt aacgttctta
     2101 ctcggaataa taatcatacc tatatccgta ttagtattct caataccatt ttttagcata
     2161 ataggtttcc aatcattagc agataattta aatataagtt ctttaataac aataaattgg
     2221 tattcaaata atatgtttta taacattggc tatattgcat tattctttat agtaacttat
     2281 ctaatattta tttttcttga actttttata atatttttac atataaaata caaaaagaaa
     2341 tttaataata ttatcttatt catattcttt ataactgcta atatgatcgt attaaactta
     2401 ataattttga agattttcta caacattcat ataaacttat attttcaaat tttcatttat
     2461 tctttatgct tctatctttt atttactcat aaagagattt acaaaatatt tgaagaaaat
     2521 aaaagtaaaa aataaaaaaa taaaaaaata aaaaaattaa tctctcaaaa agttttctcg
     2581 gcataaaagt acctctaact tttatacata aagtcatgag cataagggaa agtgccacca
     2641 cttttatatt ttggcagacc cataacgtgg tgaactcggc agtgccgagt tatttttcct
     2701 agaaaaaaag tgacatcact tttttaactc atatgtataa aaaccataac gttatgtata
     2761 catacaggtt acgtatacat atactttatg tatataaaac atacacaaaa gacatgcatc
     2821 atacacatca atttttttaa aaatacatgt ctttttgata tatatttttt ttgcgtttta
     2881 agaggtcatt tagagcattc tctaattttg agtacaaaaa tacgtaatat aaaaaaatcg
     2941 tccttttaaa acctttttag gacattttaa acacattttt atgatttgga tcaatgtaga
     3001 ataaatgtca taaacgtata gaaaaaatac gtcgtcattt ctaagtacag ataaatttct
     3061 gatgcagtac taaattatgg ggaaacctac ctgtaaaaaa taaaaagatt actatatttt
     3121 aattttattt tttctgttcg ttttttcgac accaggacgg gcgattttta cgtactgccc
     3181 atttacatgc aaatttaaaa attagcaata aatcgttccg aatttgcatt ttaaatgggc
     3241 aaacgtgccg tttgatcaca tagttcgtgt agcgacaaaa agagtataac gaaagtataa
     3301 taagcgtata aaaaaagtgt aatgatagaa aatagcatta tactttttta gtcgttcatc
     3361 gctcatcaga acaacaaata aatttttaag aaataaattt tgagagttga ccacccacgt
     3421 tctccgtaaa ctacaaatgt gggtggtcaa ctctcaaaat atttttatat ttttttattg
     3481 ttcttcttcg gtaagttcgt gaagttcact tgccaggtac tctttctgat tccaaatata
     3541 ataaatttgg taaaggtatt cagttggatc gatttcttgg ttctgttgca aagttaaaaa
     3601 ataagtgtct aaccttatgt ttaaaataat acttcgtatt aactagctag catgatgcta
     3661 attacacggc atggcgaaaa cccgtagatc tgaagaaatc tgcggttctt tttatatagt
     3721 ccataaatac attcaatgcc tttgatcgta ttctttgccg tattgatact ttgataactt
     3781 attttcctta ctttgatatg acgatgatct tgttcaatga gattatttaa atatttagag
     3841 ttacaatgac agttgggggt aagtttaaaa tctttaatca ctttggacat tgccaccttc
     3901 gttgaagggg cttggtttgt aattatcatt tgaggtttgc caaattgttt aataagacgt
     3961 ttaataaacg tatatgctga gtgattatct cgtttcttac gtaacgaaat atctagtgta
     4021 tggccatctg catcaatagc gcgatataaa taattccatt gccctttaat tttgatatac
     4081 gtctcatcta tatgccattt ataataagct tgcttatttt ttttcttcca aatttgatac
     4141 aaaataggag catattcctg tacccatcga taaattgttg aatgatgaac atagatgcct
     4201 cgttctctca atatttcaga tatatcacga taacttaatg catatcttag atagtagcca
     4261 acggctacag taatgacatc tttgtcaaat tgcttatatc tgaaataatt catcctctgc
     4321 acctcatttt ttgttgacta ttatactata tttctaactt tgcaacagaa cctaatgtaa
     4381 gctatgcaga tatacttgaa attttaaaaa taaaaaaggc ttataacgta aaacaatgtg
     4441 gtaacgtctt agaattcaag ccgaccgatg aaggttattt gaaattacat aagacgtggt
     4501 tttgtaaatc aaagctatgt ccagtttgta attggaggcg tgctatgaaa aatagttatc
     4561 aagctcaaaa agtgattgaa gaagtaatta aggaaaagcc aaaagcacgt tggttgtttt
     4621 taacactttc aacaaaaaat gcgatagatg gagatacttt agaacaaagt ttgaagcatc
     4681 taactaaagc atttgatagg ttgagtagat ataaaaaggt taaacaaaat cttgttggat
     4741 ttatgcgttc aacagaagtt accgttaata aaaatgacgg taattataat cagcatatgc
     4801 acgttttgtt atgtgttgaa aatgcatatt ttagaaaaaa agagaattat ataactcaag
     4861 aagaatgggt taatttatgg caaaaagcat tacaagttga ttatcgacct gttgtaaata
     4921 ttaaagcaat taaacctaat caaaaaggcg ataaagatat tgaatcggca atcaaagaga
     4981 catcaaaata ttcggttaag tcatctgatt ttttaactga cgatgacgaa aaaaatcaag
     5041 aaattgtaag tgatttagaa aaaggtttat atcgaaaacg tatgttaagt tatggtggat
     5101 tgcttaaaca aaagcataaa attttaaact tagacgatgc cgaagatggt aatttaatta
     5161 atacaagtga tgaagataaa ataacagatg aagaagcaaa agcacattca attacggcaa
     5221 tttggaattt tgaaaagcaa aattattatt taagacatta gtgatgactg atgtcttttt
     5281 tattgatttt ttgtaaaaaa gtactgtctt atttttgtga caaatgctgt atgtaggtca
     5341 caaaactggg caatatattg tgtcacaaaa gtgtgacact acagcttttt atgatatcac
     5401 tttaaaatta cttaaaaccc ttggaatgtc tggctttgcc agacctatta tttttgaatg
     5461 atagcaaatt ctccttatgc tcttacggag ttcttagaga aaaattgaaa tttcttgatt
     5521 tttgataaaa acgccctgca ggaatttaga aaaacatggg gaagttttaa aagattttat
     5581 gctcattttt aatttgcatt taaatgggca gtgttaaaaa attagtcact ggttttgctg
     5641 aaatttttgt ttgtgaaatt accatatatt tatttgactc atatttgcgt tttaagagct
     5701 tgtatagatt tttaagtaga agactataag atttacctct aaatctttaa aataccctct
     5761 taaaattcaa aataaaggtg tttataattt gaataagtcc tgagataaag ttttttaaaa
     5821 ggagtggttt tttgaagagg tctttattta ttttacaaat tattcttggt atttttttat
     5881 tgttttttat ttataagcaa atgaatcaaa atcatttaga tacttggttt attctttata
     5941 cagtcttttt ttatattttt tcatcgtggt ttgataaaca ttataaaaaa agttagacga
     6001 cgcatttatg ccgagaaaat ttattgatgt tgagaagaac ccttaactaa acttgcagac
     6061 gaatgtcggc atagcgtgag ctattaagcc gaccattcga caagttttgg gattgttaag
     6121 ggttccgagg ctcaacgaca ataaagcaat tggaataaaa tacacaggca ttgaatgtat
     6181 ttatggacta tataaaaaga accgcagatc tcttcagatc tacgggtttt cgccatgccg
     6241 tgtaattagc atcatgctag ctagttaata caaagtatta ctttaaacat aaggttagac
     6301 acttattttt taactttgca acagaacctt acattatcta ttttcttttc tctccatggg
     6361 cgttgttttc cacttttcgt catatctttt aacgttttat tatcttgatt ttcggttata
     6421 cttctagtag tattatattg catataaaaa gaactccagt attgatttag attagacacc
     6481 ttaatcatat tactggagtt tttttatgtc aaattttatt ttccccaagc aaaacagtat
     6541 gaaacgccgt catatcaacg cttcaaaagg attttagaaa agaacgttat ttctatatag
     6601 tatcaagaca agaagaaact cgtttcactc gtttcaaaaa ccctcatgat ttttagagaa
     6661 aaactctctt attccatcgt ctttaataaa ataatatgcc atctttccat ctttataaaa
     6721 atcaagtacc tcatttttat ataaaagcct taaatgatgt gaagttgaag caacactcat
     6781 tttcaatatc aaagaaatat cacaaacaca caactcatct tctttaatca aagataatat
     6841 gattttcaat ttcttctcat cacaaatttt ttctaaaatg ttaagtaatt tcttagattt
     6901 atcatcttct aaaaaactta aagcattgtt aactttatcc tcatgtacac agatcacatc
     6961 acaagtattt tcataactca tataaaatca caccctaaat taaaatataa atcctaaaat
     7021 tgtttgaata gtgtcatttt caataataat aaataaacct aaagctatat aaataatagc
     7081 cataatccaa cgactaaatt tctcaacaat ttctccaatt cctgggatat tagctaattt
     7141 ttgtgcagta aacaccaaga agaaaattaa aattaaaaag acaaacagag taagtaataa
     7201 attagtaaca cttaatgtca caaaatacgg aacaaataaa ccaatattat cggcgccaca
     7261 acttgctatc gtaacaattg caaccgtacc aactaattta gacaatcctt tttcattcag
     7321 ttctttttta gctctctttt ctccttcaca atcacataaa tagccacttt aattccaaga
     7381 taaattggta ttaaacccaa taaacctaat atccacttct ctgaaacata atttaataca
     7441 aaagctaaaa acaaactaac taatattaaa ataatagacc ctaaatattg accaatataa
     7501 atatctctat attctttttt agtctttgct ctagcaaaaa atattaataa aattactaat
     7561 aaatcaaatg ctgtagcaat ataaagaata gcagcagtga caaccgtttg aatcatacat
     7621 acacctcatt caaaaatatt tttgaatgta ttataactaa tatttttaaa taatcatagg
     7681 tgctttattc caattgcttt attgacgttg agcctcggaa cccctaacaa tcccaaaact
     7741 tgtcgaatgg tcggcttaat agctcacgct atgccgacat tcgtcttcaa gtttagttaa
     7801 gggttcttct caacatcaat aaattttctc ggcataaatg cgtcgtctat ttttttatct
     7861 tcatgataat catatttttc ttccatctcg tcaaaatcat catcttcata gaaaaacaaa
     7921 aagtaagcaa caacaccaat aggaataaaa aatagtgtga aaacaagaag aaactcgttt
     7981 caaaatcccc tcaaatattc taattattct ttttgaaatt cataacttta acaaccaaat
     8041 aaatagcatt tattcccatc aaaataacat acggaattaa tatatataaa ttttccaaat
     8101 gagatataaa aattaatcca agtaaaaaga aaacatttaa aatagttgct ataacgtaac
     8161 ctttatctaa cattgtgtct ttattcaaaa taaaaactcc tttttaaaaa actttatcac
     8221 aagacttact caaattataa atacctttat tttgaatttt aagggggtat tttaaagatt
     8281 taggggtaaa tcatatagtt ttctatctaa aacctacata atctcttaaa acgcaaatat
     8341 gaaccaaata catatatgct attttcaaaa acaaaatttt aaataaaacc aatgactatt
     8401 tttttaaaca ctgcccattt acatgcaaat taaaagttag cataaaatcc tttaaaactt
     8461 cccccatgtt tttctaaatt cctgcaagac attttttatc aaaatcgaga atttttattt
     8521 tttctctaag aactccgtaa ctccgtaaga gcataaggga aatttgaccc catgtataca
     8581 tggggtatct ggcaaagcca gacaattcaa agcttcaaca atatttttat gtggggtcat
     8641 aaaaagctta agtgtcacac ttttgtgaca caatatattg catttgtcac aaaaataagc
     8701 cagtactttt ttataaaaaa acagtaaaaa aagacatcag tcatcactaa tgtcttaaac
     8761 tctttaatta tttataaata atcattaccc caaaataaaa tacagaactt gaaaacttaa
     8821 tatcaatgac ttcgatttgg ttatcattaa taaaattatt gatttttcgt tctaaagaac
     8881 ttccagtcat tccagttaaa attttagtgt tcatattttt aactccttaa attttttaaa
     8941 taataatttt gcttttcgaa attccaaatt gctgtaatcg aatgtgcttt ttcttcttcg
     9001 tctgtcgttt tatcttcatc acttgtatta atcaaattac catcttcggc atcgtctaag
     9061 tttaaaattt tatgcttttc tttaagtaat ccaccataac ttaacatacg ttttcgatac
     9121 aaaccttttc tagatcactt aaaatttctt gatttttttc gtcgtcatca gttaaaaagt
     9181 cagatgattt aacggaatat tttgatgtct ctttgattgt tataaaatca tttgaattat
     9241 tgattaaaga tattatattg tttcatgttt ttacggcgca tataaagggc atgtgtttct
     9301 tcaagttcag ctttaatgga ttgcattaaa taaccttgca tagcttcaac ggtttcattc
     9361 ttttgtagca acatcgcttt aaaacgtttc aatacactta caatttcaaa ctcaacatct
     9421 tctaaacgat aataagtatc atgtgaagta ttaaatgact ttttcccttt gagtaatacg
     9481 cttttaataa tccgaatttc tctaatttca aatttactta aatagtcttg aagttgttgt
     9541 ggcaattctt cgagtacttg gaacttaagg gcgtcattat taaattcagt tttttgatga
     9601 tttgtatgat tcgaatgatg attattattt attaaagtat tagatataat atcattcata
     9661 tcatacgtat cattatcctc attttctata taattagtat tatttaactc agtatcatta
     9721 gactgtgaat ttggaagttc ttgaccactt aaattcacag ttctagaact tccaaattca
     9781 ttgttctgga actgtgaatt tggaagttcc ttggtaagac ttgcttcaat atcataattt
     9841 ggttttaata aatataatct atttggttta ttaaggccaa cacgctcttg agttaataaa
     9901 ttaaaattta ctaactcttt tttcaatttt atgatttttt gttctccata acctaagtac
     9961 tcgcacaaat gtttattact gaaaataaag taaatgttat tatttctatc tacccattca
    10021 ttttggatgg ataattcgaa acgatctttt aataatgcat acataatttt ggcttctgct
    10081 gacattttct taaaatatgc atcttcgaac aaatatttag gaagttggta aaatctttca
    10141 gtttttactt gtgataaatt gtatttctca aaattgggca taataaaaac ctcatttcca
    10201 ctttttggat agaggtaata aaacaatttt tacgtaggtt atatgttttg tacttgcact
    10261 tatatgatta gatatatata atacaagtat caaaaaatta tataaacaga cgaatgcgaa
    10321 tcgttttatt accgagagtc gatgctacgc caatagtatc gactctttta atattcacaa
    10381 agtaatatta acacttttaa gattgtatat aaagcttttt aagtttagtt gaaagaacat
    10441 tgtaacttta aaatgataaa aattcaccac tttagtacct aattagtcac ctatagaagg
    10501 ttttaacggc taattaggta ctaaagtagt gaaataggta gtaaatttag atgtcgaaag
    10561 atgaaaaaat atttgttagg tggtaaaatt taggtaccaa tttatgtacc taaggatgaa
    10621 tgttatgaaa actattaaaa tggttgctga tgaattgaat gtaactaaac aaactattgt
    10681 taataatgct aaaaacttaa atatatcttt taaaaaagaa aatggaatta attatattaa
    10741 tgataatgat tgtttaaaaa ttatagaaaa gatcactaag aaagaaagga caatgcaaaa
    10801 taaagaatca ataaaaaaag aaagatttaa tgaaaatact gcagagtttg aaaagcatat
    10861 atacaataat tcaaatggtt ttgagtcatt aaaaacaaaa gtaaatgaat tagaaaagca
    10921 aatagaaatc tttgaaacta gagctaaaaa tgacgaaaaa tatattgaga atttaactaa
    10981 acaactagat caacaaaata gcaatgttaa tacattaaat aaactgttgg agaatcaaca
    11041 aatattagct ttagaaagta ataaaaagat tcaaaaacta gaaaaccaat tagaagaaga
    11101 aagacagctt aattactctt ttgatacagc gactaatgat agacaaagca ttaatccgca
    11161 agaagcaact tttactgaag aatatcaaaa tagcaaccaa caacaaaaga aaatacaacc
    11221 aatagaagca gaattaaatc ataagggcat aactaaagcg aaaaaggatg acagttcaaa
    11281 cgaagacgta ttaaagagag atgataaact atctgaagaa atagagagtg gacctgagga
    11341 cagggaagta gaaacaccta aaaaggggtt ttggagtcgt ttgtttggta gctaaaataa
    11401 ttaattaggc actaaaagtt tataactttt agtgcctttt atatagtgag aacttctggt
    11461 aatcatcagt tatgttaaac tctaacaaaa actaaattat cagaagaatt atctagggta
    11521 ttaaacatag gtaaatcaat tttctatcgc caatagtata aacatcatcc atattaatct
    11581 gaagatagct acataattct ttaacagcat agcctttatt tgtataaggc gccataaact
    11641 ctattaaata tggtttgttt tgaggtttct atgtttaatc atttaatttt tcattatata
    11701 aatcgaataa ttataaaaag tcatcatact ttttattttt taaaaatatt tgaaaattta
    11761 atagtaatcc aattataaga tcaaatatca ttatcattat aatcaaggca actataatca
    11821 ctgtgacact cgttacataa caagctagta atctccagat aaaattgaca ttttcaccaa
    11881 ttccataact taacatatta caaagtagta aaagaataat aatacctata ctgtaaatta
    11941 aaattgtcag tgtatatttt ttaataactc tattaggaaa caatagttca tctattaggt
    12001 tctttttcac cagtatctct cgttcaattc tatctttgtc acagattttg attttactat
    12061 tttttatttt ttcctctaat aaaataacct cgaacgatct gctaattttt aataaatatg
    12121 caggaaaagc taatgttaag cataatgtaa ttaattcatt tacattgttc atgtaactta
    12181 taaaatagat gaaagttgct actagtgctc ctaaaaatat agttatatta agttctacat
    12241 caaatatttt aaaaatatct gctctattca tcagttaatc atcctttcaa ggtttattaa
    12301 tactaataaa ttattagata taggtatatc atattattaa tttaagaaat tgtcttttat
    12361 aattttactt aataataaaa aagtagaacc atttaaaatt aatggttcta ctttttaact
    12421 attactaatt ttaaaaataa actaatctac aatatctaaa aatatatgtt tagtactatt
    12481 tttgtttagt tatatcaagt gatttgggaa ttaacaaata gacaactatt gaaatgataa
    12541 tcatgataat cccacctact aaagcagttg ctacaaaagc atcattaaat gatgttacag
    12601 cctcgtttgc aagctgtttt atccccgtag ctttagctac ttcgacagcg cccactacag
    12661 attcttcagc tacatgagct aaatctccaa ctataccttt tgatgaaaaa gatgaaatat
    12721 ctaaaaatac acgataaagc atagaagata ggctaccaag tactgctaca ccaaaaacat
    12781 ttccaaggtc atacatagac tcttcaacag cagctgcatt acctgctttt gatgtaggtg
    12841 tttctaacat tattagagca gatgcaactg ctagtgaagc cataccagct ccaactaaaa
    12901 ttaatgctaa agccattata gaatatgata atggatgacc aaagaaatac ataataaaca
    12961 tgccaatggc tgcaattcca attccggaag gtaacactat tttcggtcca aatcgcgccg
    13021 ctaatccggg tgcaattggt gcaaacacca tatctcctat tgccataggt aataggtata
    13081 agccagcttt aaaaggagaa agttcttcca caacctgtaa ccattgtgaa gctaataaca
    13141 aaacagatgc cattgcaaac attgtcataa atgcagcaat tgtaccagct gaaaatgatc
    13201 tctttttaaa aagtcttacg tctaacattg gatcagaact tgataaatta cgtttaacaa
    13261 atatcactat catggtaatt gctaatacta ttacaaccca tggaataata tctgctagtc
    13321 cttcttttga aaattctttg atactccata ccagtccaat catgcctgca attgataaaa
    13381 ttgtagaagg aatatcccac gagtgagact tttcttttga taacttagac tctggtaata
    13441 aaaataaacc tgctacaact gctattatcg caaacggtac attaattaaa aatgccgagt
    13501 gccatgaaaa ttgctcaagt aaagctcctc cgataattgg tccaaaaaca gcacctatcg
    13561 atgaagcgat tgaccataca gctaatgcag tggccctttc tttagggttt tcaaaaatta
    13621 ctcttatcat tgaaagagta gttggcatta ttaaagcacc tgcaatacca agtaaaaatc
    13681 gaatagctat tacgaactct gcactttctg cgaaaaatat agctaatgaa acgaggccaa
    13741 ataaagcaaa tccagttaat aatgcttttt ttcttcccca tttatcagca aaggcactca
    13801 atggaattat aaagccagct aaaacaagag agtatatatc aactatccat aactgttggg
    13861 taccagaagg ctctaactct cttactaatt ccggtaaagc cataattaat attgtcatat
    13921 ccattgtaac aacaaacaaa ctaacagcta atactactag tgcagtccat cttttttttg
    13981 atgtcatcat atcagtagtt tttgtaaaaa atgaaatcat ttaagttccc tccaatcctt
    14041 atagaccgtg cgatcggtct ataaggatta taatctattt ttttacatat tacaacaaaa
    14101 aatcttgcga aatttaaatg gctgtattgt gttatacaat tattctttga attttttgtg
    14161 ctatcattga tagtacttaa tactcattaa aggcgtgatg aacttgaaag ataaaatact
    14221 aggtgtcgca aaggaattat ttataaaaaa tggatataat gccactacta ctggagaaat
    14281 tgttaaatta tcagaaagta gtaaagggaa tctttattat cactttaaaa caaaagaaaa
    14341 tctattttta gaaattttaa atatagaaga atctaaatgg caagaacagt ggaaaaagga
    14401 acaaatcaaa tgtaaaacta atagagaaaa attttattta tataatgaac tatctttaac
    14461 aaccgaatac tattatccac ttcaaaacgc aataattgaa ttttacactg aatattataa
    14521 aactaatagc attaatgaaa aaatgaataa attagaaaac aaatatatag atgcttatca
    14581 tgtaattttt aaggagggta atttaaatgg cgaatggtgt attaatgatg ttaatgctgt
    14641 tagtaaaata gcagcaaacg ctgttaatgg aattgttacc tttacacatg aacaaaatat
    14701 taatgaaaga attaaactta tgaacaagtt ctctcaaatt tttttaaatg gacttagtaa
    14761 ataattatat atatattctt gaaataccaa taaatattat ttctaaatta cgttcgttat
    14821 tgagacaaaa tttaatagta ctactacaca aaaagagagt gcgaattcgc actctctttt
    14881 tgtgataaat gaatggttaa gaaaataatt catccacagt tgtatcaaac aatcttgcca
    14941 acttaaatgc taatgtcaat gtaggatcat atttattgtt ttctattgca ttaatagttt
    15001 gcctagacac ttttaattct ttacttaaag tttcttgaga aattcctttt tgttttctat
    15061 attctctaat tctatttttc attaatttaa cctttagatg tatatttttt atttgtagta
    15121 tagtaattaa acagcataag aaatagtgct acaattataa agaaaatttc tggatattga
    15181 gaaaaccaag atccttcaat acttggtgac aaacctgtaa atttaagcac tagtgtaaat
    15241 aacatacaat atacaatcca aataaaactt ttagccagta tttcaataaa cattttacgt
    15301 tgtctttcat cgtatcgatc ttgttgtcct tttttatcta atgtttctga aggtaaatat
    15361 ttgttagtta tagccgtcca taaacaagaa aaaattaaaa taataataaa aggaattaaa
    15421 ttcattataa cacctcataa atgtaaaaag tatttgacat ttatgagtgt aaatattttt
    15481 gatacaaatg tcaaatactt tttacattat aatatatttt aaaacacctt attagtaaaa
    15541 caattactat atagaaagct gcgaactcgt actctttttt cttgtataat tattaaaatc
    15601 tcaattcaat aatatgttat ggaatttgag acactgtgag agacgctcat ttgcattgac
    15661 aatcaattta tcaagataat cccttatcat gtttaattct ataaactgtt tgtcttgtga
    15721 tattaacttc tttcgcaatc ttactaatcg ctttgccttc ttctaacatt tccaccacgc
    15781 gatgataaat aacacgtttc tgtgggtctt tagcatttgg tgaataaagt aaagggcgcc
    15841 ctttatatac gcctttttcc ttcgcaactt gaatcccttg cgcttgtcga cgtttacttt
    15901 catttctctc ttgttctgaa accattgcta atatttgaat gattaaatct ttcataaact
    15961 tatccagtaa tggattgcca attacttcat tcatcatagg taagctggta atcattaact
    16021 gaacgtcttt ttcttttaaa taattcacag tttcaataat ttcatcatag ttacgtccta
    16081 aacgatcaat agattccaca acgaatcgat ctcccattct gacaaaattg agtgcttctt
    16141 gaaatacagg tctattttcc actgactttc ccgactgttt ctctgtaaag attttctcca
    16201 caccaaacgt ctttaaatta tccaattgtc tttctaaatt ttgatctatc gatgatactc
    16261 tcgcataacc tataatcatt catcttcact ccataataaa tatacaccct aatcatacgt
    16321 tttaattgtt ataatttcaa caattctttt tgtatggtta gggtgtgtcc tgtctatttt
    16381 tatctttctt aaaacttagt aatattattt atctttattt tcttgattat ttaacctatt
    16441 gagataacga tagattgtgg tacgtgaaac tttccattgt tctgcaatag ttttaattgg
    16501 tgttccatta tcataaagtg ttttgagtaa ctttaaatct tgtttattta atttttcggg
    16561 acgacctcca tagcgtcctc tagcacgagc ggcaattcgt cctgctgaag aacgttctaa
    16621 aattaagttg cgttcaaact ctgcaaatgc tgcgaataaa tgaaataaca attgtcctgt
    16681 agaacttgat ttatccattg ttatattttc ttctaaacta tgaaaactca cgcctcgatt
    16741 attaagttca ttaactaatg tgattaaatc ttccatatta cgccctagtc tatctagtct
    16801 ccaaacaaca atcgtatctc ctgccctcgc aaattcaatg gctttatcta aaccaggacg
    16861 tttacttttt gatccactta tgtggtcgct aaatatcttt tcacaaccat attgatttaa
    16921 ttgatcttcc tgcaaattta aattttgtaa accagttgaa actcttgcat aacctatttt
    16981 caaaatacaa acctcctata tacatcttca ttgtatcata acttaattct aaccatattt
    17041 atgaacatag attttctgtt gggttattga acactaaaat atgtatactc gctatatata
    17101 tagacataaa aagagagtgt atagaaaatg gttattttct gtacacagtt ttaaatatca
    17161 aaaacattat ttacatttta cgtttaagaa ctaatggtta aaaatttcat tttgtcaaaa
    17221 acgttcgttt ttgagactag aattttatgc cctacttact tcttttattt tcattcaaat
    17281 atttgcttgc atgatgagtc gaaaatggtt ataatacact caaataaata tttgaatgaa
    17341 gatgggatga taatatgaaa aagaaagata cttgtgaaat tttttgttat gacgaagaaa
    17401 aggttaatcg aatacaaggg gatttacaaa cagttgatat ttctggtgtt agccaaattt
    17461 taaaggctat tgccgatgaa aatagagcaa aaattactta cgctctgtgt caggatgaag
    17521 agttgtgtgt ttgtgatata gcaaatatct taggtgttac gatagcaaat gcatctcatc
    17581 atttacgtac gctttataag caaggggtgg tcaactttag aaaagaagga aaactagctt
    17641 tatattcttt aggtgatgag catatcaggc agataatgat gatcgcccta gcacataaga
    17701 aagaagtgaa ggtcaatgtc tgaacaaaag gttaaactaa tggaagaaga aatgaacgtc
    17761 tatcgggtcc aaggatttac atgtgcaaat tgtgcaggaa agtttgagaa aaatgttaaa
    17821 aagattccag gcgttcagga cgcaaaagta
//
