LOCUS       NZ_CP110940            13636 bp    DNA     circular CON 06-JAN-2024
DEFINITION  Klebsiella pneumoniae subsp. pneumoniae strain LC-1736/18 plasmid
            pIT-1736-ColE, complete sequence.
ACCESSION   NZ_CP110940
VERSION     NZ_CP110940.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN29934016
            Assembly: GCF_026247905.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae subsp. pneumoniae
  ORGANISM  Klebsiella pneumoniae subsp. pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 13636)
  AUTHORS   Di Pilato,V., Principe,L., Andriani,L., Aiezza,N., Coppi,M.,
            Ricci,S., Giani,T., Luzzaro,F. and Rossolini,G.M.
  TITLE     A multiclonal outbreak by KPC carbapenemase-producing Klebsiella
            pneumoniae resistant to ceftazidime/avibactam and other novel
            beta-lactamase-inhibitor combinations mediated by different
            resistance mechanisms
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 13636)
  AUTHORS   Di Pilato,V.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-NOV-2022) Department of Surgical Sciences and
            Integrated Diagnostics (DISC), University of Genoa, V. Benedetto XV,
            6, Genoa, Italy 16132, Italy
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2022
            Assembly Method                   :: SPAdes v. 3.14.1
            Assembly Name                     :: GMR162
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 85x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/05/2024 18:27:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,847
            CDSs (total)                      :: 5,723
            Genes (coding)                    :: 5,582
            CDSs (with protein)               :: 5,582
            Genes (RNA)                       :: 124
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 89
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 67 of 141
            Pseudo Genes (incomplete)         :: 79 of 141
            Pseudo Genes (internal stop)      :: 15 of 141
            Pseudo Genes (multiple problems)  :: 17 of 141
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP110940.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..13636
                     /organism="Klebsiella pneumoniae subsp. pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="LC-1736/18"
                     /isolation_source="bronchoaspirate"
                     /host="Homo sapiens"
                     /sub_species="pneumoniae"
                     /db_xref="taxon:72407"
                     /plasmid="pIT-1736-ColE"
                     /geo_loc_name="Italy: Lecco"
                     /lat_lon="45.852176 N 9.414998 E"
                     /collection_date="2018-10-26"
                     /collected_by="Clinical Microbiology and Virology Unit, A.
                     Manzoni Hospital, Lecco, Italy"
     gene            <1..585
                     /locus_tag="NPY06_RS29040"
                     /old_locus_tag="NPY06_29040"
                     /pseudo=""
     CDS             <1..585
                     /locus_tag="NPY06_RS29040"
                     /old_locus_tag="NPY06_29040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]; GO:0043022 - ribosome binding
                     [Evidence IEA]; GO:0003723 - RNA binding [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3/pyocin S6 family cytotoxin"
                     /name="colicin E3/pyocin S6 family cytotoxin"
     gene            595..852
                     /locus_tag="NPY06_RS29045"
                     /old_locus_tag="NPY06_29045"
     CDS             595..852
                     /locus_tag="NPY06_RS29045"
                     /old_locus_tag="NPY06_29045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            937..1086
                     /locus_tag="NPY06_RS29050"
                     /old_locus_tag="NPY06_29050"
     CDS             937..1086
                     /locus_tag="NPY06_RS29050"
                     /old_locus_tag="NPY06_29050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            2567..4531
                     /locus_tag="NPY06_RS29055"
                     /old_locus_tag="NPY06_29055"
     CDS             2567..4531
                     /locus_tag="NPY06_RS29055"
                     /old_locus_tag="NPY06_29055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            4531..5262
                     /locus_tag="NPY06_RS29060"
                     /old_locus_tag="NPY06_29060"
     CDS             4531..5262
                     /locus_tag="NPY06_RS29060"
                     /old_locus_tag="NPY06_29060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            5269..5799
                     /locus_tag="NPY06_RS29065"
                     /old_locus_tag="NPY06_29065"
     CDS             5269..5799
                     /locus_tag="NPY06_RS29065"
                     /old_locus_tag="NPY06_29065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(5827..6006)
                     /locus_tag="NPY06_RS29070"
                     /old_locus_tag="NPY06_29070"
     CDS             complement(5827..6006)
                     /locus_tag="NPY06_RS29070"
                     /old_locus_tag="NPY06_29070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            6075..6452
                     /locus_tag="NPY06_RS29075"
                     /old_locus_tag="NPY06_29075"
     CDS             6075..6452
                     /locus_tag="NPY06_RS29075"
                     /old_locus_tag="NPY06_29075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            complement(6514..6813)
                     /locus_tag="NPY06_RS29080"
                     /old_locus_tag="NPY06_29080"
     CDS             complement(6514..6813)
                     /locus_tag="NPY06_RS29080"
                     /old_locus_tag="NPY06_29080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(6803..7066)
                     /locus_tag="NPY06_RS29085"
                     /old_locus_tag="NPY06_29085"
     CDS             complement(6803..7066)
                     /locus_tag="NPY06_RS29085"
                     /old_locus_tag="NPY06_29085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            complement(7372..>7662)
                     /locus_tag="NPY06_RS29090"
                     /old_locus_tag="NPY06_29090"
                     /pseudo=""
     CDS             complement(7372..>7662)
                     /locus_tag="NPY06_RS29090"
                     /old_locus_tag="NPY06_29090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /name="Exc2 family lipoprotein"
     gene            complement(7697..10702)
                     /locus_tag="NPY06_RS29095"
                     /old_locus_tag="NPY06_29095"
     CDS             complement(7697..10702)
                     /locus_tag="NPY06_RS29095"
                     /old_locus_tag="NPY06_29095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /protein_id="WP_001143775.1"
                     /translation="MPVDFLTTEQVESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHDEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISQSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLGENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASDLVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQASVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGALGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
                     /name="Tn3-like element Tn3 family transposase"
     gene            10864..11421
                     /locus_tag="NPY06_RS29100"
                     /old_locus_tag="NPY06_29100"
     CDS             10864..11421
                     /locus_tag="NPY06_RS29100"
                     /old_locus_tag="NPY06_29100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001217881.1"
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="recombinase family protein"
     gene            11655..12209
                     /locus_tag="NPY06_RS29105"
                     /old_locus_tag="NPY06_29105"
     CDS             11655..12209
                     /locus_tag="NPY06_RS29105"
                     /old_locus_tag="NPY06_29105"
                     /EC_number="2.3.1.82"
                     /function="resistance to aminoglycosids"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003159191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ib'"
                     /protein_id="WP_014454105.1"
                     /translation="MTNSNDSVTLRLMTEHDLAMLYEWLNRSHIVEWWGGEEARPTLAD
                     VQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGWWEEETDPGVRGIDQSLA
                     NASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAIRCYEKAGFERQGTVTTP
                     DGPAVYMVQTRQAFERTRSVA"
                     /name="aminoglycoside N-acetyltransferase AAC(6')-Ib'"
     gene            12279..>12494
                     /locus_tag="NPY06_RS29110"
                     /old_locus_tag="NPY06_29110"
                     /pseudo=""
     CDS             12279..>12494
                     /locus_tag="NPY06_RS29110"
                     /old_locus_tag="NPY06_29110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001424636.1"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /name="nucleotidyltransferase domain-containing protein"
     gene            12560..13264
                     /locus_tag="NPY06_RS29115"
                     /old_locus_tag="NPY06_29115"
     CDS             12560..13264
                     /locus_tag="NPY06_RS29115"
                     /old_locus_tag="NPY06_29115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            <13319..13489
                     /locus_tag="NPY06_RS29120"
                     /old_locus_tag="NPY06_29120"
                     /pseudo=""
     CDS             <13319..13489
                     /locus_tag="NPY06_RS29120"
                     /old_locus_tag="NPY06_29120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /name="serine hydrolase"
     ARG             11656..12206
                     /name="aac(6')-Ib'"
                     /gene="aac(6')-Ib'"
                     /gene_name="aminoglycoside N-acetyltransferase AAC(6')-Ib'"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             12292..12548
                     /name="aadA15"
                     /gene="aadA15"
                     /gene_name="ANT(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="97.14"
                     /coverage="32.32"
     ARG             11605..12209
                     /name="AAC(6')-Ib9"
                     /gene="AAC(6')-Ib9"
                     /gene_name="AAC(6')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="98.97"
                     /coverage="99.01"
     Typing          complement(1190..1768)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          4532..5259
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.34e-150"
ORIGIN
        1 gaagccgata aaaaggtaaa agaggcagag gcaaataaag atgattttgt gacttataac
       61 ccgcctcatg aatatggctc cgggtggcag gatcaggttc gctatcttga taaggatatt
      121 cagaatcaga atgagaaatt aaaagctgcc cagacatctt taaacgaaat gaatgaatcc
      181 ttatccaggg ataaggctgc gctttccggg gcgatggaga gccggaaaca aaaggagaaa
      241 aaagcgaagg atgcagaaaa taaattaaat gaggaaaaga aaaaacctcg taagggaact
      301 aaagattacg gccatgatta ttttcctgat cccaagactg aagatattaa ggggttggga
      361 gagttgaaag agggtaaacc taaaacccct aaacaaggtg gtggtggtaa gcgggcccga
      421 tggtatggtg ataaaaagcg taaaatttat gaatgggatt cccagcacgg tgagcttgaa
      481 gggtaccgcg ccagtgatgg cgaacacctc ggggcattcg atccaaaaac gggtaagcag
      541 gttaaagggc cggatccaaa acgaaacatt aaaaaatatc tttaagaggt aaatatgggg
      601 cttaaattac atattcattg gtttgataag aaaaccgaag agtttaaagg tggtgaatac
      661 tcaaaagact tcggtgatga tggttctgtc attgaaagtc tggggatgcc tttaaaggat
      721 aatattaata atggttggtt tgatgttgaa aaatcatggg tttcgatatt acagccacac
      781 tttaaaaatg taatcgatat tagtaaattt gattactttg tatcctttgt ttaccgggat
      841 ggtaactggt aagcaaaagt tatcaaggat gatttgaaat acagacttcc ggtgttcagg
      901 gatgaatacc ggggttttta aatacaggga aggtatatga aaaaggtaaa ggttgttttt
      961 ctttttatat tgattttttc aggctttctt ctggtcgcat gtcaggcaaa ctatatccgg
     1021 gatgttcagg gtggaacggt ggcaccatcg tcctcctctg aactgacggg gatcgcggtt
     1081 cagtagaaaa gatcaaagga tcttcttgag atcctttttt tctgcgcgta atcttttgcc
     1141 ctgtaaacga aaaaaccacc tggggaggtg gtttgatcga aggttaagtc agttggggaa
     1201 ctgcttaacc gtggtaactg gctttcgcag agcacagcaa ccaaatctgt ccttccagtg
     1261 tagccggact ttggcgcaca cttcaagagc aaccgcgtgt ttagctaaac aaatcctctg
     1321 cgaactccca gttaccaatg gctgctgcca gtggcgtttt gcgtgctttt ccgggttgga
     1381 ctcaagtgaa cagttaccgg ataaggcgca gcagtcgggc tgaacggggg gttcttgctt
     1441 acagcccagc ttggagcgaa cgacctacac cgagccgaga taccagagtg tgagctatga
     1501 gaaagcgcca cacttcccgc aagggagaaa ggcggaacag gtatccggga aacggcaggg
     1561 ttggaacagg agagcgcaag agggagcgat tcatcggaaa cggtgatgat ctttaagtcc
     1621 tgtcgggttt cgccactcct gactgattca tggttgagcc accggctccc acagatgcac
     1681 cgaaaaagcg tctgtttatg tgaactcagt caggagggcg gagcctatgg aaaaacgcca
     1741 cctgcgtggc cttgccgttt tgcctcacat gttagtcccc tgcttattca cggaatctgt
     1801 gggtaacttt gcatgtgtcc gcagcgcccg ccgcagtctc acggccggag cgtagcgacc
     1861 gagtgagcga ggaggcgcaa tttccccggc acctacaaga cggacaccgg acgcgctgat
     1921 gtggcatatt gtcccctgat taagtcttta tattccctga taataaatta ccaggatagg
     1981 tgaatcatat cggtttttcg ctgaacattt tacgttaacc tatctctgtt gcttttttct
     2041 ccttacggag aaatacaggt catccccgcg agggcgtggc tgacctcagg gggatatccc
     2101 ctgcttacgc tggctggacg ccaccgacgc acggtctctc cccctctttc tggctccgtc
     2161 cggctggacg ccggccacgc cagaaattca cccggccccc gtcaggctca cgcctgacca
     2221 cccacaaaaa tccacggtgc tggacgcacc tggcgaagca gcaaagctgc tcctgatttt
     2281 gcgggtggtc agccgctcgc tatggcgaac tctgacgggg gccggaacac cggaaaagac
     2341 cgcactgggg tgccgccttt tcctctcaca cgctggggcg tgctcgttgt tcctccgggg
     2401 ctgcgccttt tccgcatggg gcggaaagag gctggcctcc gtggtgaaag ctgaacgcaa
     2461 tcaccacgga cgtgaccgcc gccgccatgc cttggggcat gtccgcggct tgtgcagcgg
     2521 gggctgcaca tcacgccggc aaaccatcgt ctgaaggaga gagaacatgt ttaatacgga
     2581 ttcgcttgcc tggaagtggc acattccgga gctggcccgg cagatttatc cgtgggtcag
     2641 ctggctgtac caggagtatt acggtctggc cggggctttc ctagttatcg gcctgttttt
     2701 cggtctggct gaactttggg ccggacggat gcgttttgtg gggctgagtc ataaggagcg
     2761 acgggagtat gccgatcgct ataagcgcga taataaacgg ccagcgccat tttcggtgct
     2821 ggcctcgctg gattcgcccg ggcggatggt cagggcacgt cgacatgtct ggaactacgc
     2881 gtactggctg accggcgcgg ccggtctggc ccttctgggg gggctggttg tcgccgtgtt
     2941 tatcgagagc tggggagaaa ccgtcctgcg tccggacctc tacgcaaacg cagattatta
     3001 cctgctgcag ccggctaacc tgttcgggat tgcctggtgc gcgggcgggc tggctgtcgg
     3061 gattgtgttg gcgcggctgc tggcgttcct gctgcttgac ggtcattttg cggctgctga
     3121 cgaggcggtg aacgcgaaac tgaatcagga gagccggcgc agcagccagc ggacaggaga
     3181 gatgaccgac gtgcgccacc tgcatttcgg ggagccggta ccggttaatg cgctggccga
     3241 tttttcctcg gagcaggccc ggcaggagca ggcggtgttt ctgggtaagg atgagcaggg
     3301 caagccggtg ctggttccgc gtgatacctg gcgcaagacc aacattcaga tcctcggcct
     3361 gcccgggagc ggcaagagcg tgatggccac caacgcgctc attcgctgcg tacgcgattt
     3421 cggggacgcg gtggtgtact tcgaccccaa aggggacgca tgggcgccgc acgtcttccg
     3481 ggcgcactgt ccggacttca ccctgctgga tctgcggccg gggaaaccgg cgcagctgaa
     3541 tctgttccgc gatctcgacc agtacgcgct gaaaaacctg ctgattgccg ggcttaacct
     3601 gggcgagacc ggcgacgtgg cggaccacta ccgcatcagc gagcagaaag cggcgaagct
     3661 gattgcggag cagtttccgc agggggcaaa cattcagcag gtgctggcgg cggcgtacgc
     3721 gctgccggag gccctgaaaa aggacgtgaa ggggttgatc actaggctgg aaaacgtcgc
     3781 tgacctgagc gtcctgcaga cggacagtgg catcgatgtg gcggggatta tcaacggcgg
     3841 cggctgcctg tacgttatcg gctcgatgga cgacgaggcg gtgatccgtg tgcaaaaaat
     3901 gctgtttgcc cgctgcgcgc aaatcatcat tgcgcgggac gagttccggg agtggccaca
     3961 cgtcagcgtg atgctcgatg aaattaaata tctgctgtcg aagtatgtac tgaacgcact
     4021 ggggacgctg cgcagccggg actgcaatct gttgctcgcg caccagtcgc tgggcgattt
     4081 cgggcagtgc gggcaggatc tgcccgctga atttgtgaaa accacggtac tggataacac
     4141 gccgatccgc tggttttacc gggcggccag cctggagtcc gcgcagtggg cggcggggca
     4201 gaccggggaa atcagggtgg acgtggagcg ccgccgtgcc agccgggagg cggggaacgt
     4261 ggagcatatc agcggggaca gcttcatcca gaaggaggcg cggccgctgt ttgacgtgaa
     4321 caccctgcaa cacctgccgg acgggttcgc ggtcatgacc gggctgggtg tggcccggat
     4381 ggcgttcagc agtccgctgc gggttgagcg ccgggaaatc ccgttgcagc gtttcccggt
     4441 gctggcgaaa accgatcccc tggcggagtt ccggcccccg gccgacggcg gcgggccgaa
     4501 agcggatgat gattttgcgg ggatttactg atggcgctgg agctgtacaa cgtcagccac
     4561 gcgaaacgac aggcgcggaa cgcggagaaa acccggctga ccctgcgctg gttgcgggaa
     4621 gagctgtgtt ccacggcgga gctggttgcg cggcggctgg ggattgcggc ggtgcagccg
     4681 gtctaccgct tcctcgacag cctggtggcg aaagggctgc tggtccggac caaatatccg
     4741 gtggacggcc gtcaggtcag cgtgtggggg ctgacgccgc atggcgtggc gttctcgttc
     4801 gacgaggacg aaccgctggc ggatgttatt ccgtttcagc cgtcaagggt gtcggcagca
     4861 catctgccgc accggctggc cgtgcaatcc ctgcgccttg atatggaagc cagaggggcc
     4921 accggctggc gcattctgca ccgtctgagt cttaaaggca tgaaagtgcc ggacgccctg
     4981 gcggagctgg acggtaaaac ggtggcgttt gaggtggagc gcaccgtcaa gagccgtcgc
     5041 cggtatcagg aagtggtgtc cgggtatctg ttcaaccgca aagctaacgg catcgatgaa
     5101 atctggtaca tctgcccgga ccgggcgacg caggtcaggg tgcagcgggc aatcctgtcg
     5161 gtggatgaaa tcgtgaaccc acagaccggc gaggcccgca aaacggcaga gctggatcgt
     5221 gaacggttgt ttgcgtgctt taaatttatg acaacggagt gagggattat ggcgctgtac
     5281 atggtattta ttgaagacgc ggaggaccgg aacggcgagc gctgcatcat gccgaccagc
     5341 gagcatctgg aagatatggt ggtgctcgcc tggcagaccg gggcgtatgt tttctgtttt
     5401 gtcgaccggg cccagcatct ggcgatgatg aaatccatcg ggatgtatga cgagcggctc
     5461 aacagcgacg aaaaagccac gtactttttc actggtaaaa atccgcaatg ggaacggaac
     5521 aaacccacag gaatgaagct gtgtgattac ctctatcgca aggtggagcg gttcgccatc
     5581 gagaacggtg tgcaggtggt tgatgccggg aagtgctcac cggagcagat taacgcgatg
     5641 attgacgtgg tgagtgagcg gcacggggaa agcgcggtga acgagaagct gaaagcggag
     5701 ctgatgcggg aatataacag ccgctatttt aacgtgccgg tacctgaact gccggaggac
     5761 aaacctgccc gccggtggtg gccgttcggc aaaaaataaa tgccagcacc ggccatgccg
     5821 gtgctgttat tcctccccga gcttatcccg catcacctgc cagagtgttt ccgcatcctc
     5881 gtgtagccgc tcgcacatgt cggccggggt atccatatcc agctcattca gtttatcgag
     5941 caatagcagc gactgctcct taataaattt agccatattg agggctgttt tttcctgttt
     6001 tgtcatgatt ctttccttcc gggcatggtg tgcgcctgtc aggtatactg tctcaaaaat
     6061 agcggggtga gacaatggcg tgggtgacgg tgagacaggc gacggaactg acgggtaaag
     6121 cccgaagttc cctgtatcgg gatatggcga aaggccgcgt atcataccgt acggaagctg
     6181 atggcggccg ggtggtggat accagcgagc ttatccgggt gtacggtgag ttaagacagg
     6241 atgagactca cgagcgggac gagttgagac tgtcgggtga gactgaaaaa atggcctccg
     6301 acgcgttgat cgcggagata aaagcactca gggaggaggt ggccgggcta cggcaggaaa
     6361 tgcagtccat gagactgctg gaacacaaac cggagacagc agagaccccg gccggaacac
     6421 cgcgccggtg gtggccgtgg ggaaaacgct gacgcgctgt gcttgtccaa ccggcgacgg
     6481 ccacgcaatg aattgcgtcc ccgtcaccgg ttattagaga acaatatggg gattctggcg
     6541 ctggccgacc acggccagaa cccggacttt tctggtctgg tcatcaacat catagaggac
     6601 atgctgtccc atcagactga tccggcgaac gtcctcgcca tagcgtgagt ccacttcata
     6661 gagtcgcggg aagtcggcca gtttgtccgc cgcagcgaga acccggtcgg taacgttctg
     6721 cgcatcccac agggatgaat tttccgcgat atagtcaaac agcgtcgtta catcctcgat
     6781 ggctccctgc ttccattcca cgtcatacgg catcgcgcag ttcctgataa cggccatgca
     6841 ggcgctggcg gagttgttcc gtggtcatac ccggacgcgt gtcagcacgg gcggcggtca
     6901 ctttggcgcg aacctgatct tcatactctg cctgggccag ttcttcgtta gccagtcgct
     6961 gcaacagcgc agctttgtcc gggccacctt ccggcagtat gcggggcagg ctttcagcca
     7021 gttcccgaag aaagttggcg ttttcgtagt gtgtagtgtt gctcattgcg gagcctcccg
     7081 ggttaatgcg gcaatatgaa ggaagtttag cagggggcgg tctgaaagaa tatggtcgtg
     7141 tcagtcaggc tgatgaagca gaaagtcggt aaaaaagggc ttacggcatc cattttacgt
     7201 caaaacatat gccatgcagt tgcgtgcata ggcatgcatt aggataaaat ttatcgggcg
     7261 cgtttccggc agttttccgg gggggttgtt gcctgtttta tcccgtagcc gccggaaacg
     7321 ccctgagccc gtctgagcgg tgcgcgtaat gacgcgttat ggtaaatcca cttactgtct
     7381 gccttcatag ccatcgagat aaacagctga aatggtgtca gccagtagcc ttgatttttt
     7441 cggtgtgagg tctttgctgc ggtaatcggt acccgcaaat tgtgttgtgc cttggagtga
     7501 gtttaaaaat tcctgactgt gaaactgctg aatgcgttgc tgcacatcac tccgtgattt
     7561 tccggtcgct ttatcctttg cgcccatatc ccagaactgc cggaaaaaag gcaccatcat
     7621 tcgtgttgtg tcagctttct gggtggaaaa attgggatca aaaggggtct gacgctcagt
     7681 ggaacgaaaa ctcacgttaa gcaacgtttt ctgcctctga cgcctctttt aatggtctca
     7741 gatgaccttt ggtcaccagt tctgccagcg tgaaggaata atggccgagc atattgatat
     7801 gtccgtggca aagcggggag aggcgtgcga tatcttcatc attcagtgtt tcaccctgcg
     7861 cccggagatg atccagagct gcctgcatat aaatagtgtt ccataacacg acggcgttag
     7921 tgaccagccc cagagctccc aactgatctt cctgaccgtc ggtatatcgt tttcttatct
     7981 cacctttttg accgtgacag atggctctgg caactgcatg acggctttct ccccgattaa
     8041 gctgggtcag aatgcgccgg cggtaatctt catcatcaat ataattaagc agatacagcg
     8101 ttttgttgat gcgccccact tcaatgattg cctgagtcag tccggaggga cgttcacttt
     8161 tcagcaatga acggaccagc actgaggcct gtactttgcc cagcttcagg gagcctgcgg
     8221 tccggatcat ttcgtcccac tgaaggacta tttttcgggg atctgattgc cctctggcaa
     8281 tatcattcag cacgccatag tcggcatcat ggtccattcg ccagaaaacc gaagcaccgg
     8341 catcagccag gcgtggagaa aactggtatc ccagcagcca gaaaaggcca aagacaagat
     8401 cgctggcacc tgccgtatcg gtcataattt cggttggatt cagcccggtc tcctgttcca
     8461 gaaggccttc cagcacaaag atagagtccc tcagcgtccc cggtataacg atgccatgaa
     8521 agccggaata ctgatcggac acaaagttgt accaggtgat ccctctgtta ttaccaaagt
     8581 atttgcggtt cggtccggca ttgattgttc tgactggcgt aacaaagcgc attccatctg
     8641 cagatgccac ttctcctcca ccccatatct gtgccagtgg cagcgttgcc tgaaaatcaa
     8701 ccagtctggc attagcgctg gtgatagttt cagcccgcag atagttcgct tttgtccagt
     8761 tcagccggtg tcgggtcagt gcaggaacat ttgatctgat cagtggttcc agaccgatat
     8821 tgcaggcttc agccatcagc acggcgctga tgctgacggg cagatcatca actctggcac
     8881 tggcttcact ggcatggaaa aactcatcag caaatccggt atgggcgtta atttcgagca
     8941 gcaactccgt taaatccacc ggagggagca gatcactgat cattttgctc agtcgtttca
     9001 gactgtccgg ctcatcaaga ctggcgaggg gagaaattgt caaccggggc ttcgggccag
     9061 aaacatcgag ttcgacagcc tcattttcgc caagacgtgc agcaacctgt ctgtaacgac
     9121 tatcaagctg atggcccaga gattttattg cttcctgcgg gtctgtcggg tgccccaaag
     9181 aacgataaac cttaatccga tttgcctgcc agtcagcacc ctgtagtaat cttgcacgag
     9241 gatctcccca ccggttactg ccggtaacgt agacatccct ccgtctcaga ctatcctgca
     9301 gtttactgag aaagcagagc gtgtatcccc ttcgggtgat atgtttttcc ttgttaatca
     9361 ccagccgttt ccatgactga ctgatgattt ccgttggtgc gtcgtcaaaa aactgccgcc
     9421 gtgagctgaa ctcccggctg aggtagtcac aggcattcag agtggtaacc ccggcaggtg
     9481 cggatgaaaa tttaacggta ttcagcagat ggggcaggaa acgacgaacg cgcccgtact
     9541 gctccaccat ttcgtcatga aaattatcgt ctgagggccg ggcaatttca cggacaagcg
     9601 tgatgatttc agccagcttt tgcctaggga tgtagctgaa cacctcagca cgaatcgatt
     9661 cgtccggtgt ttcttctttc agcaagtacg aacatgcgct ggcgagcgcc aatgcagatt
     9721 tatccagatc cttcagcgag cggagccgtt ttttctgccc aatctttctg gcgtcacgga
     9781 tgataacggc cagcatggcg tccagaacgt ccagtgcatc atccagcgcc agcgtttccc
     9841 atgcaaggac aaaggcaacc agaaccgcca tccttttctg cggtgacatc ctggcaatat
     9901 tgaacaccga agtcatacca gcataacgtg cgagattttt caggcgcaca gccgggagtg
     9961 tactcaggtt ttcagcatgc aggccaaaat cgttcagagt tttccagcgt tcaattgctt
    10021 cattaaacgc cggaccactg atggtcacag ggcctttttt cagtgattcc agtaaagaca
    10081 ggcggctgca atcagttggc cccagcagca tctccagctg tgaacgctgt tcggctgacg
    10141 gtatcagtgc cagtttgttc cacaggcgca acgtcgcctt ttcccttacc tctgaaatca
    10201 accgggtcag cgtggtggct ccggggagaa taatacgatg ttgcataagc caccctgtcg
    10261 ccaggtcgaa aagcaggcca ggacgttcgt tgcttatcca gctccgggta tataaaagac
    10321 gggtaaggcg aaatgtccag ggccaggcaa attcacgata ctgatagtgc tgacgtatca
    10381 gcgctgcatg ctcacggcgg gtattttccc tctgaccgta ttctgcaaga acggtgatat
    10441 cacgaatccc gagctgtctg gcggtaaaat gccggacgcc ggaaggaata tgattcatgt
    10501 cagtaagaaa agtgcccaga aaacgcacac acccgatttg cagggcaata ccaagtcgat
    10561 tgtgatcacc ccggcttttc ccgataaatt ctttatccgc ttcatcaaga tgaaaataac
    10621 gcgccagctg aagttcatcg ggttcgccag tgaacctgcc ataactctca acctgctcag
    10681 tggtcaaaaa atcaacgggc atatcggcct ccctgcctga cggctttttt aacacaactg
    10741 caaccgttcg aaatattata aattatcaga catagtaaaa cggcttcgtt tgagtgtcca
    10801 ttaaatcgtc attttggcat aatagacaca tcgtgtctga tattcgattt aaggtacatt
    10861 tttatgcgaa tttttggtta tgcgcgggtc tcaaccagcc agcagtccct cgatattcag
    10921 atcagagcgc tcaaagatgc aggggtaaaa gctaaccgca tctttaccga caaggcatcc
    10981 ggcagttcaa cagatcggga agggctggat ttgctgagga tgaaggtgga ggaaggtgat
    11041 gtcattctgg tgaagaagct cgaccgtctt ggccgcgaca ccgccgacat gatccaactg
    11101 ataaaagagt ttgatgctca gggtgtagcg gttcggttta ttgacgacgg gatcagtacc
    11161 gacggtgata tggggcaaat ggtggtcacc atcctgtcgg ctgtggcaca ggctgaacgc
    11221 cggaggatcc tagagcgcac gaatgagggc cgacaggaag caaagctgaa aggaatcaaa
    11281 tttggccgca ggcgtaccgt ggacaggaac gtcgtgctga cgcttcatca gaagggcact
    11341 ggtgcaacgg aaattgctca tcagctcagt attgcccgct ccacggttta taaaattctt
    11401 gaagacgaaa gggcctcgtg atacgcctat ttttataggt taatgtcatg ataataatgg
    11461 tttcttagac gtcaggtggc acttttcggg gaaaagtgcg cggaacccct atttgtttat
    11521 ttttctaaat acattcaaat atgtatccgc tcatgagaca ataaccctga taaatgcttc
    11581 aataatattg aaaaaggaag agtatgagta ttcaacattt ccaaacaaag ttaggcatca
    11641 caaagtacag catcgtgacc aacagcaacg attccgtcac actgcgcctc atgactgagc
    11701 atgaccttgc gatgctctat gagtggctaa atcgatctca tatcgtcgag tggtggggcg
    11761 gagaagaagc acgcccgaca cttgctgacg tacaggaaca gtacttgcca agcgttttag
    11821 cgcaagagtc cgtcactcca tacattgcaa tgctgaatgg agagccgatt gggtatgccc
    11881 agtcgtacgt tgctcttgga agcggggacg gatggtggga agaagaaacc gatccaggag
    11941 tacgcggaat agaccagtca ctggcgaatg catcacaact gggcaaaggc ttgggaacca
    12001 agctggttcg agctctggtt gagttgctgt tcaatgatcc cgaggtcacc aagatccaaa
    12061 cggacccgtc gccgagcaac ttgcgagcga tccgatgcta cgagaaagcg gggtttgaga
    12121 ggcaaggtac cgtaaccacc ccagatggtc cagccgtgta catggttcaa acacgccagg
    12181 cattcgagcg aacacgcagt gttgcctaac ccttccatcg agggggacgt ccaagggctg
    12241 gcgcccttgg ccgcccctca tgtcaaacgt taaacatcat gagggaagcg gtgatcgccg
    12301 aagtatcgac tcaactatca gaggtagttg gcgtcatcga gcgccatctc gaaccgacgt
    12361 tgctggccgt acatttgtac ggctccgcag tggatggcgg cctgaagcca cacagtgata
    12421 ttgatttgct ggttacggtg accgtaaggc ttgatgaaac aacgcggcga gctttgatca
    12481 acgacctttt ggaaacggca ctgttgcaaa tagtcggtgg tgataaactt atcatcccct
    12541 tttgctgatg gagctgcaca tgaacccatt caaaggccgg cattttcagc gtgacatcat
    12601 tctgtgggcc gtacgctggt actgcaaata cggcatcagt taccgtgagc tgcaggagat
    12661 gctggctgaa cgcggagtga atgtcgatca ctccacgatt taccgctggg ttcagcgtta
    12721 tgcgcctgaa atggaaaaac ggctgcgctg gtactggcgt aacccttccg atctttgccc
    12781 gtggcacatg gatgaaacct acgtgaaggt caatggccgc tgggcgtatc tgtaccgggc
    12841 cgtcgacagc cggggccgca ctgtcgattt ttatctctcc tcccgtcgta acagcaaagc
    12901 tgcataccgg tttctgggta aaatcctcaa caacgtgaag aagtggcaga tcccgcgatt
    12961 catcaacacg gataaagcgc ccgcctatgg tcgcgcgctt gctctgctca aacgcgaagg
    13021 ccggtgcccg tctgacgttg aacaccgaca gattaagtac cggaacaacg tgattgaatg
    13081 cgatcatggc aaactgaaac ggataatcgg cgccacgctg ggatttaaat ccatgaagac
    13141 ggcttacgcc accatcaaag gtattgaggt gatgcgtgca ctacgcaaag gccaggcctc
    13201 agcattttat tatggtgatc ccctgggcga aatgcgcctg gtaagcagag tttttgaaat
    13261 gtaaggcctt tgaataagac aaaaggctgc ctcatcgcta actttgcaac agtgccctga
    13321 taaatctgga gccggtgagc gtgggtctcg cggtatcatt gcagcactgg ggccagatgg
    13381 taagccctcc cgtatcgtag ttatctacac gacggggagt caggcaacta tggatgaacg
    13441 aaatagacag atcgctgaga taggtgcctc actgattaag cattggtaac tgtcagacca
    13501 agtttactca tatatacttt agattgattt aaaacttcat ttttaattta aaaggatcta
    13561 ggtgaagatc ctttttgata atctcatgac caaaatccct taacgtgagt tttcgttcca
    13621 ctgagcgtca gacccc
//
