LOCUS       NZ_CP110893            22675 bp    DNA     circular CON 22-APR-2024
DEFINITION  Citrobacter freundii strain CF1807 plasmid pCF1807-5, complete
            sequence.
ACCESSION   NZ_CP110893
VERSION     NZ_CP110893.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN31693425
            Assembly: GCF_026240835.1
KEYWORDS    RefSeq.
SOURCE      Citrobacter freundii
  ORGANISM  Citrobacter freundii
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Citrobacter; Citrobacter freundii complex.
REFERENCE   1  (bases 1 to 22675)
  AUTHORS   Li,X.
  TITLE     Sequence characteristics of the clinical Citrobacter freundii
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 22675)
  AUTHORS   Li,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-NOV-2022) Faculty of Graduate Studies, Hangzhou
            Medical University, Xi hu district, Hangzhou 310000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. v0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_026240835.1-RS_2024_04_22
            Annotation Date                   :: 04/22/2024 05:41:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,783
            CDSs (total)                      :: 5,661
            Genes (coding)                    :: 5,524
            CDSs (with protein)               :: 5,524
            Genes (RNA)                       :: 122
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 83
            ncRNAs                            :: 14
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 41 of 137
            Pseudo Genes (incomplete)         :: 93 of 137
            Pseudo Genes (internal stop)      :: 23 of 137
            Pseudo Genes (multiple problems)  :: 18 of 137
            Pseudo Genes (short protein)      :: 1 of 137
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP110893.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..22675
                     /organism="Citrobacter freundii"
                     /mol_type="genomic DNA"
                     /strain="CF1807"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:546"
                     /plasmid="pCF1807-5"
                     /geo_loc_name="China"
                     /lat_lon="29.86 N 121.56 E"
                     /collection_date="2018-07-17"
                     /collected_by="zhangxiaofan"
     gene            13..714
                     /locus_tag="OQW59_RS02795"
                     /old_locus_tag="OQW59_02790"
     CDS             13..714
                     /locus_tag="OQW59_RS02795"
                     /old_locus_tag="OQW59_02790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011172001.1"
                     /GO_process="GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA family replication protein"
                     /protein_id="WP_254919869.1"
                     /translation="MTDKSLSLKSSVSPTGVAKQSPCYNVASRKRRRFLNRWIKSLATE
                     AGRIKIKNELRRRIRHNRYWVNEANKFGLEALCELMLAILDDLDLRDWQTIHNLETLAD
                     RAGLATRSDAGHKSISRASRGCDRLSWLNAIISEKAPFNPYDARCACKHIEVTEDFFAI
                     LGIPLKQVYRERARLLKANPEEIIFSGDVRLIAIKVENWTRKAAAGLARMKAKREVARQ
                     RKREYYSPTFA"
                     /name="RepA family replication protein"
     gene            1579..1815
                     /locus_tag="OQW59_RS02800"
                     /old_locus_tag="OQW59_02795"
     CDS             1579..1815
                     /locus_tag="OQW59_RS02800"
                     /old_locus_tag="OQW59_02795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019844796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system CcdA family
                     antitoxin"
                     /protein_id="WP_025861853.1"
                     /translation="MATTQRATQSVTMTVERALLSRAREAGINLSATLTAALDAELRQY
                     EAKKWQEENNEALEALNRFHDEHGCFSDEYRTF"
                     /name="type II toxin-antitoxin system CcdA family
                     antitoxin"
     gene            1819..2133
                     /locus_tag="OQW59_RS02805"
                     /old_locus_tag="OQW59_02800"
     CDS             1819..2133
                     /locus_tag="OQW59_RS02805"
                     /old_locus_tag="OQW59_02800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016941020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CcdB family protein"
                     /protein_id="WP_061586429.1"
                     /translation="MQFTVYSNTGKSAVYPLLLDVTSDIIGQLNRRIVIPLLPVEKYPG
                     STRPERLVPLVRLNDGKEYAVMTHEMASIPARSLGAVFCDASLHRTQVKAAIDFLLDGI
                     "
                     /name="CcdB family protein"
     gene            complement(2444..2938)
                     /locus_tag="OQW59_RS02810"
                     /old_locus_tag="OQW59_02805"
     CDS             complement(2444..2938)
                     /locus_tag="OQW59_RS02810"
                     /old_locus_tag="OQW59_02805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001607198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4326 domain-containing protein"
                     /protein_id="WP_223230020.1"
                     /translation="MTKKISISEIIFISDPRGFIRKISEDKQFRIREVNSAEDAEYAII
                     FRDKRQDIGDFKLPENAKVKVVLLNLTLVVNKDRGDKFDVYIGRGTIWGNPYQIGVDGD
                     RDEVIRKFKYDFDKEFLKPFDNIDKNASSLKGKIIACHCKPYACHGDIIADYINSLDDG
                     E"
                     /name="DUF4326 domain-containing protein"
     gene            complement(3007..3459)
                     /locus_tag="OQW59_RS02815"
                     /old_locus_tag="OQW59_02810"
     CDS             complement(3007..3459)
                     /locus_tag="OQW59_RS02815"
                     /old_locus_tag="OQW59_02810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006626223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="WP_151355700.1"
                     /translation="MEHVNIHTIGFTKKTAEHFFNALKKNGVIRVIDTRLNNNSQLSGF
                     AKAKDLEFFLRKICNIDYVYRSELAPTKKILDDYKNKNITWEQYSYEYLNLMEQRLISS
                     KLSSVDVDNGCLLCSEDKPHNCHRRLLAEYLKQQWLNQKTDINHIL"
                     /name="DUF488 domain-containing protein"
     gene            complement(3460..4107)
                     /locus_tag="OQW59_RS02820"
                     /old_locus_tag="OQW59_02815"
     CDS             complement(3460..4107)
                     /locus_tag="OQW59_RS02820"
                     /old_locus_tag="OQW59_02815"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_061586427.1"
                     /translation="MRTTHQLLCLAKSWKNGGFCIAGKNDNNQWVRTITANPINNAIFH
                     HGNAIKPLDFFQATTINHAPQGHQTENHIIDENVSFTVNGHCAANDLDDYVDTPATLWG
                     TGTSSNYGVNDKIIIGQSVVNNSLYLIKPDDTVIVQMQNEYGTDKLRIRFTYNSNEYLL
                     TTTDMGIQNYFRDENNRLNDGEEEELDGVSYLTISLAEPLNGNLYKVVAGVF"
                     /name="hypothetical protein"
     gene            4376..5023
                     /locus_tag="OQW59_RS02825"
                     /old_locus_tag="OQW59_02820"
     CDS             4376..5023
                     /locus_tag="OQW59_RS02825"
                     /old_locus_tag="OQW59_02820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815856.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_004178130.1"
                     /translation="MTAVIALANGKGGVKKSSMSRAIATEYTKAGWGVLGLDMDIDQGS
                     FLDWGQRRLRNGFEPPVTIQGCGTVSQAKKQIESGQWDLIVIDSAAYATKSLLSLIDIV
                     DLLVLPTGFSVDDLRTTVTTVNALRNKGHSTDKMAVVFAGVSESESEYRAALEYLQPCG
                     VPVIPGAIPFLTSFSQAQDKGLALTESPFPGPRQKADDVVQGVIDRLTTLTQ"
                     /name="ParA family protein"
     gene            5064..5297
                     /locus_tag="OQW59_RS02830"
                     /old_locus_tag="OQW59_02825"
     CDS             5064..5297
                     /locus_tag="OQW59_RS02830"
                     /old_locus_tag="OQW59_02825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011998900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004178129.1"
                     /translation="MANVPAKPRNTKGEPPSQADTEHGFNPTRKSADGRKAQLNLYIDM
                     ELKREFRSIAAANDMKHGELFEAYQEFWKKHH"
                     /name="hypothetical protein"
     gene            complement(5335..5676)
                     /locus_tag="OQW59_RS02835"
                     /old_locus_tag="OQW59_02830"
     CDS             complement(5335..5676)
                     /locus_tag="OQW59_RS02835"
                     /old_locus_tag="OQW59_02830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004929374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_011172022.1"
                     /translation="MIFAKFQSLTHKIDTMVIRDIKREMPLKYWSFKVAEWIARIGMIG
                     FVCTFLTYFGLGLIMQHSGQNLPESFTEGCAQAIVALIAIALVGFLVRGGLYVDLEKRI
                     LDKWQSYVQ"
                     /name="hypothetical protein"
     gene            complement(5737..6210)
                     /locus_tag="OQW59_RS02840"
                     /old_locus_tag="OQW59_02835"
     CDS             complement(5737..6210)
                     /locus_tag="OQW59_RS02840"
                     /old_locus_tag="OQW59_02835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009309960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="WP_061586426.1"
                     /translation="MKCRSRLLVFLPLLFPALCLADFSGRVVRVVDGDTVQVLTDGKMM
                     KVRLNGIDAPESGQPFGQRSKQNLLKLAVQKQTEVIANNTDRYGRWLGTLMIGGININA
                     EQVKAGMAWAYRYHGRASDETMLRLEEEARRHRIGLWSSPDPVEPWKWRKQNK"
                     /name="thermonuclease family protein"
     gene            complement(6247..7002)
                     /gene="mobC"
                     /locus_tag="OQW59_RS02845"
                     /old_locus_tag="OQW59_02840"
     CDS             complement(6247..7002)
                     /gene="mobC"
                     /locus_tag="OQW59_RS02845"
                     /old_locus_tag="OQW59_02840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_023316386.1"
                     /translation="MLIHNVAERKEAANRKMLALLTFLKEETYSDFKTLKKVVGFKGKS
                     HRPTYALLNKAVALGFLIKHEYPVIAGKKSLWGITMQGLAMVVKPDDKVFPGYFEPGKL
                     KYWTLEHRLLNHRVRIALEEKGGQGWLNGDRGEFIARYPGVRHRPDGIITLDSGAIVAV
                     ETERSMKTRARYINIINSHLAASDAGRWHYAMYVMPDDKTKTSLIRLFDSIKTVMRNNV
                     PVPFDAKNREMFLFRTIDELEQAAASGGQ"
                     /name="mobC"
     gene            complement(7011..8747)
                     /locus_tag="OQW59_RS02850"
                     /old_locus_tag="OQW59_02845"
     CDS             complement(7011..8747)
                     /locus_tag="OQW59_RS02850"
                     /old_locus_tag="OQW59_02845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017346477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system DNA-binding
                     domain-containing protein"
                     /protein_id="WP_117140887.1"
                     /translation="MGSHLMQRLNAFADAFSFFLLWLQNSPVILSLLAGLTLPFIFHLP
                     REERKNAPFWLKSVACVSIFFFIFGTISPLTIQGLSYFFKSLDNNILFRVPLWFMTIMF
                     TASGLIFHIAARRLLAGEIDNLKHRMIKKSKLERNTRTDVRKVKELLPDPIEYNPLDYI
                     DLKKGVFIGLNKDDQPQYITIKEFKTQHAAIIGTTGSGKGVTATVLLYQAILLGEAVFV
                     EDPKDDEWAPHVLREACKKAGKKFTLINLNKLNFQLDLLADISHEQLEELFNAGFSLAK
                     KGEASDFYRISDRRAARNTSAIYEKGMTLRDLFNTDFVQSLREDVPAFCGELEEIALVN
                     SINATKGFSLKEVFDEGGCCYIIGSTRNQKIISAQRMILTRLIQIAETRDRINSTPRTV
                     AIFLDELKYHLSRPALEGLGTARDKGVHIFMAFQAIDDLRDCPSDLNGDSVIGAIIENA
                     KFKLIYKIQNPETAEWAAKMTGSILVDDEMRKVRTDLSLTEKVDTDRMIRQAESYYVDS
                     NMFLNLPEKVGFVFTSTELPRATKMFQVQVKKENIELLSFEYKQATPEKNESQEHKPSI
                     NL"
                     /name="type IV secretion system DNA-binding
                     domain-containing protein"
     gene            complement(9527..9832)
                     /locus_tag="OQW59_RS02855"
                     /old_locus_tag="OQW59_02850"
     CDS             complement(9527..9832)
                     /locus_tag="OQW59_RS02855"
                     /old_locus_tag="OQW59_02850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011172016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032152569.1"
                     /translation="MINEDLFIKNIHSKNQDRISVALVYDTLSKEAHRGCGLYYEIYES
                     CFIGLLRDHLSELNEADANKLRRYAESKGTKIDDASYSEALEAERECRAEIYREQM"
                     /name="hypothetical protein"
     gene            complement(9866..10171)
                     /locus_tag="OQW59_RS02860"
                     /old_locus_tag="OQW59_02855"
     CDS             complement(9866..10171)
                     /locus_tag="OQW59_RS02860"
                     /old_locus_tag="OQW59_02855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="WP_061586437.1"
                     /translation="MKKTVIAAAVLCLTAGTPIYSFAADPCEVVLCMYGKATGNSGGGE
                     CSSAERAFFKINAFKKHHRFNPGKTFDMRKEFLGECKAADPESISKILSKFGRVKG"
                     /name="conjugal transfer protein"
     gene            complement(10207..10605)
                     /locus_tag="OQW59_RS02865"
                     /old_locus_tag="OQW59_02860"
     CDS             complement(10207..10605)
                     /locus_tag="OQW59_RS02865"
                     /old_locus_tag="OQW59_02860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_073853226.1"
                     /translation="MIKKLKVIMLAAIVTGCSSPPPPVPVEWDKAAVPLNTSLPQWSDN
                     NIIVPSPTVNGKWTSSISAQSFYDTIWTPAVFYAVAHSTRIVVTAQSGTDFFNAKNWLR
                     QNGAKGVIEYQPVFNCLTCRETTIYFSR"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            complement(10602..11627)
                     /gene="virB11"
                     /locus_tag="OQW59_RS02870"
                     /old_locus_tag="OQW59_02865"
     CDS             complement(10602..11627)
                     /gene="virB11"
                     /locus_tag="OQW59_RS02870"
                     /old_locus_tag="OQW59_02865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227785.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_000125558.1"
                     /translation="MTAKNISLDRYKQRFFGDFLELPGLTEIAVNRPGELYTKINGVWE
                     QHAVPLSYEDCYNFARCLAKHHGDNIEDIKPGLSATLESGERCQVIVPPACERDTVSIT
                     IRKPSKVQIPHQSYIDAGFYNRVTGEEKTETHDEELIALYNTKNIPLFMEKCVEYGKTL
                     AVAGETSTGKTTYMKMLIGYIPVHLRISTIEDNPEITFFIHKNYVHLFYPSESSDEKGS
                     IVTPASLLRWNYRMNPDRILLTEVRGAEAWDFLKITGSGHEGSMTSIHAGSAKEAIDGF
                     ITRCYENPQCAQLPYTFMLRKVLDSLDVIVSIDLDGNVRRMNDIYFRPIHRNQYFEEMK
                     A"
                     /name="virB11"
     gene            complement(11617..12867)
                     /gene="virB10"
                     /locus_tag="OQW59_RS02875"
                     /old_locus_tag="OQW59_02870"
     CDS             complement(11617..12867)
                     /gene="virB10"
                     /locus_tag="OQW59_RS02875"
                     /old_locus_tag="OQW59_02870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_061586436.1"
                     /translation="MNDENKVPVPDEAQASPAHAEDDIATLEREARAKREAKLLNAQDD
                     EEKDPVQPAVNKLKKRKRGKATAFLAIVAVALIFLAWGGNWVYRNILWQPTEEKKQDTA
                     PQTNKTDYRQRNDLGMSTDTAEEEPEQQDNGQSSTGGTGQAAPAAPPELNKASFLIRRD
                     GSATTQNPVKTRQQEMTLTSATSTGQQDSSAATNTASPSPGQSPAPVRRIPYNPDLYIP
                     ENTSIPCSLDRRFVSDRAGKLRCTVTTDIWSASGNTKLIEKGTTASLLYRAIAEEGMKH
                     GQGRAFIIATKLRTRQAPYLDIPLVDTSAAGELGEAGVDGWIDSHFWERFGGALMVGMI
                     PDIGAWASNSAGKKDRNTDYTENSRQAMADMARTTLENSINIPPTLYKNQGEIINLITG
                     EDIDFSNIYTLRLKNDR"
                     /name="virB10"
     gene            complement(12911..13819)
                     /gene="virB9"
                     /locus_tag="OQW59_RS02880"
                     /old_locus_tag="OQW59_02875"
     CDS             complement(12911..13819)
                     /gene="virB9"
                     /locus_tag="OQW59_RS02880"
                     /old_locus_tag="OQW59_02875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_213858555.1"
                     /translation="MMKKLTFTALALMMCGAAWGAAIPQASRYDSRVQQVIYNPQNVTV
                     VNTKPGFMTTLVFDNDEAVISAKPGFDEAWEATPDANRVNVRPVALTQGAPGEDGNTTQ
                     VVIPPNSRDWHTNMLVVTSKRLYNVELNVIDDKSAQQPAFQVSYRYPGEERDKASREAT
                     ARQREWEQKQQHASVQKALNSAQTPRNWSYTKYPGKGSFNIVPDFAYDDGRFTFVGFSP
                     SKSIPSVTKELNGKEHVVNSSIQKKGDFTVLVIQEVTPRLVLRSGNAVVGLENSGFGKV
                     HAADGSTVSRQVERVEKPESN"
                     /name="virB9"
     gene            complement(13816..14499)
                     /locus_tag="OQW59_RS02885"
                     /old_locus_tag="OQW59_02880"
     CDS             complement(13816..14499)
                     /locus_tag="OQW59_RS02885"
                     /old_locus_tag="OQW59_02880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_057517071.1"
                     /translation="MSEQKLIAESRTFEQQMIERDKRATKAGFVVGGVGLLIAVLALVA
                     VVVMLPLKQTDVELYTVDNHTGRVEHVTRTSKTSLTATEAYQKAMAANYVKVRERYVYP
                     SLQDDYETVQVYNAPQVNDDYLALYAGKNAPDKVYKNGAHTVKVEILSNQITDATAPDR
                     VATIRYKKIIRRLADNSTRNEYWDARFTFHSNPDKEMSDAEREINYFGFTVTSWQTDRE
                     IRGGE"
                     /name="type IV secretion system protein"
     gene            complement(14721..15794)
                     /locus_tag="OQW59_RS02890"
                     /old_locus_tag="OQW59_02885"
     CDS             complement(14721..15794)
                     /locus_tag="OQW59_RS02890"
                     /old_locus_tag="OQW59_02885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_061586435.1"
                     /translation="MSGGVFVGVEKHLIGGITDATKGLMMSYSSMMMGLAVTSATIYIM
                     WRGYQTLAGKLSTPMEDTMWDIMRMAIILSFVANISGYLDGVIDAINGLKEGFSGSDNI
                     WQLLDSLWNNAKVLGKTLHDMDNSTYIKDEGMTAQFYVWLGIFVLMIITAFVSMIAEVM
                     ILLLSITAPIFIFCLMYGFLRPMFNNWLQNIFAAILTILLSSLSLRIVVNYLNSRLALA
                     TQGAAQANIVELGAQVCLAGICAAILIYLSAKLAAALAGASATVSMQGLAAVGIGAAAF
                     GAGKLAGGAVKETKRSAQDNIQGWKDANAGKPGKPGGELGYNASKARKYAIEQMIARNE
                     ARRLAQSRDSAVKKFNS"
                     /name="type IV secretion system protein"
     gene            complement(15805..16032)
                     /locus_tag="OQW59_RS02895"
                     /old_locus_tag="OQW59_02890"
     CDS             complement(15805..16032)
                     /locus_tag="OQW59_RS02895"
                     /old_locus_tag="OQW59_02890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012885322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_073853223.1"
                     /translation="MRLLTISLLALSVFLVSGCKEEAKTTKWYKDHPEELKAVYEKCQK
                     TGSASENCKNANEAHWQIQQLNAPTVDLNS"
                     /name="EexN family lipoprotein"
     gene            complement(16046..16756)
                     /locus_tag="OQW59_RS02900"
                     /old_locus_tag="OQW59_02895"
     CDS             complement(16046..16756)
                     /locus_tag="OQW59_RS02900"
                     /old_locus_tag="OQW59_02895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011172010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_061586434.1"
                     /translation="MKTHFYALIFACSLASPLAQAGGILVFDATAKLENVRQWQKEAKQ
                     WMETAQHYKDQIRAYKDQLATATGVRDIASFVDQAKSLKADLEKLRKPGQALNDLLLSG
                     GSSGQFDALYEKYKIFDTCNAERSGNYANVCKQQVINKAIQLEQTDEIQNQVSQTLGEI
                     NSLSNRVALAKDSKESQDLANSIQLKSVMLNTLTTQWEMSVKAAEKREKVLEAERVKQW
                     NQQQLNAPTVDLNS"
                     /name="type IV secretion system protein"
     gene            complement(16775..19513)
                     /locus_tag="OQW59_RS02905"
                     /old_locus_tag="OQW59_02900"
     CDS             complement(16775..19513)
                     /locus_tag="OQW59_RS02905"
                     /old_locus_tag="OQW59_02900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="WP_061586433.1"
                     /translation="MAKLLKAMKRPAALWGVPMVPLLAVTGVTIIVAIWTSVALLFLLP
                     VQFLVMKSLTRNEPMRFNLIAVWLRAKGKPVANRLFGATTFMPVEHDDVDIKEFLDAMK
                     LNQCATIKKYIPYSSHIHQHVVRSPKSDLYCTWELMGTPFDCESDESLQFGTNQLHGLI
                     RSFEGMPVTFYIHNDRNTFTDNLHKDSGNPYADEVSRLYYASVGLFRRNRLFLTVCYRP
                     FVSLEKAERKRMKDSQKLKELDGALLEMLEIKSTLDTALSRYGARPLGTFTEGNAVFSS
                     QLAFYEYLLTHQWRKVRVTRTPAYDVMGAAALFFSAESGQINHANGTQYFRGLEVKEFS
                     EETATGMMDSLLYAPCDYVITQSYTCMSREEAKKAIKRTRRLLMSADDDAVSQRLDLDV
                     ALDLLTSGKIAYGKHHFSIMVYSPSLESLVADTNEISNALNNIGITPVPAEISLSAAYM
                     AQLPGNYNLRPRKGELSSQNFVELAALHNFYPGKRDKAPWGDAMALLRTPSGDGYYINL
                     HNTLADKDEFNEKNPASTCILGTNGSGKTMLMTFFEIMQQKYGREDSFSPDAKTKRLTT
                     VYLDKDRGAEMNIRALGGRYYRVISGESTGWNPFSLPATKRNINFIKQLMKILCTRNGS
                     TISPRDERRLSDAVNAVMNDEPQYRVYGITRMLENLPEPATKEAQENGLSIRLSQWAQG
                     GEFGWVFDNESDTFDISNCDNFGIDGTEFLDDASVCAPISFYLLYRITSLLDGRRLVIF
                     MDEFWKWLRDPVFKDFAYNKLKTIRKLNGMLVVGTQSPAEIIKDDIAPAVIEQCGTQIL
                     AANPNADRAHYVDGMKFEPEVFDVVKGLDPQARQYVVVKNQFRRGDTKRFAARVTLDLS
                     GIGRYTKVMSGDAPNLEIFESIYREGMQPHEWLDTYLAKAL"
                     /name="VirB3 family type IV secretion system protein"
     gene            complement(19526..19831)
                     /locus_tag="OQW59_RS02910"
                     /old_locus_tag="OQW59_02905"
     CDS             complement(19526..19831)
                     /locus_tag="OQW59_RS02910"
                     /old_locus_tag="OQW59_02905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012885319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_012457109.1"
                     /translation="MKLFSKVKELISRASAYVLAPAMSVFAASPAFADGFSRANTIMEK
                     VSSGLHGLAAITITVAVIWIGYKTLWKGESLSQCGYIIIGGILIGGGSEIGALLMS"
                     /name="TrbC/VirB2 family protein"
     gene            complement(19828..20538)
                     /locus_tag="OQW59_RS02915"
                     /old_locus_tag="OQW59_02910"
     CDS             complement(19828..20538)
                     /locus_tag="OQW59_RS02915"
                     /old_locus_tag="OQW59_02910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_061586432.1"
                     /translation="MLSTTAFLAVAMQCAATVHPSTSLDVARVESGYNPYAIAEIVPKP
                     ERKPGDKGFITHMPKSKEDAVSITNQIEAKGRRYSVGLMQITSTNFKRYGVTATDLFNP
                     CINLSVYEKIITDCYQRGGTLKRALSCYYSGNFSTGQQQEPAFSKTSYVQRIGYSPADT
                     RYAVPGTRDDIATPAATLKATPVDAPTRPRVVWPGAIVRGVPAQLRQKKAATIYYPAQV
                     VRGNRDVTTKEEEK"
                     /name="lytic transglycosylase domain-containing protein"
     gene            20537..20659
                     /locus_tag="OQW59_RS02920"
                     /old_locus_tag="OQW59_02915"
     CDS             20537..20659
                     /locus_tag="OQW59_RS02920"
                     /old_locus_tag="OQW59_02915"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_255093128.1"
                     /translation="MATSEQKNGDQPDDEQNEQPASERKPGIGIVSIHCAVSLF"
                     /name="hypothetical protein"
     gene            complement(20656..20874)
                     /locus_tag="OQW59_RS02925"
                     /old_locus_tag="OQW59_02920"
     CDS             complement(20656..20874)
                     /locus_tag="OQW59_RS02925"
                     /old_locus_tag="OQW59_02920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_011172006.1"
                     /translation="MRKPTYNVYVTQETQPDENGEKNTYWTKVGAAFAHNGKSGLNIMI
                     TPGISVSGKLVLLEPKDDAAPQAAPVS"
                     /name="hypothetical protein"
     gene            complement(20879..21094)
                     /locus_tag="OQW59_RS02930"
                     /old_locus_tag="OQW59_02925"
     CDS             complement(20879..21094)
                     /locus_tag="OQW59_RS02930"
                     /old_locus_tag="OQW59_02925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_061586431.1"
                     /translation="MPKSVPGKSSTAVIYIGQKRYQELAKQAREISYLSESNIRPSTFL
                     QFLMDEFGEQARTELLRQLLSEKQKE"
                     /name="hypothetical protein"
     gene            complement(21166..21621)
                     /locus_tag="OQW59_RS02935"
                     /old_locus_tag="OQW59_02930"
     CDS             complement(21166..21621)
                     /locus_tag="OQW59_RS02935"
                     /old_locus_tag="OQW59_02930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011172004.1"
                     /GO_process="GO:0006354 - DNA-templated transcription
                     elongation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]; GO:0140673 -
                     transcription elongation-coupled chromatin remodeling
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination NusG
                     family protein"
                     /protein_id="WP_073853220.1"
                     /translation="MYEWYVLYCNNQDVERITRRVEGLDVEVFCPRYIKVTPRKDCRAV
                     RQEEKALFPNYLFLCFDVNITHTSTITSIPGAHGFVSFGSTPCTVPKSVITAIECARLM
                     ALNPDEDAIECRNIAPNLLAKIQELSLIRSPLQRQVAFSKLLQNQYH"
                     /name="transcription termination/antitermination NusG
                     family protein"
     gene            21872..22228
                     /locus_tag="OQW59_RS02940"
                     /old_locus_tag="OQW59_02935"
     CDS             21872..22228
                     /locus_tag="OQW59_RS02940"
                     /old_locus_tag="OQW59_02935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011172003.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_032455359.1"
                     /translation="MVPKRLKEAREAAGLSQEKLSELVGVEGVNPRSRMSNYEAGRFAP
                     PFEFVCRVADVLGYPEYYFYIVNDVTAKLLLRMHRGEQNLHEDIEFEAKKMAEQLEDAR
                     RLVAQLTECLKHRP"
                     /name="helix-turn-helix transcriptional regulator"
     Typing          2..714
                     /name="IncFII"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.867"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(12915..13816)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.003"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(13820..14499)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.559"
                     /coverage="100.0"
                     /evalue="1.01e-129"
     Typing          complement(14725..15794)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.039"
                     /coverage="100.0"
                     /evalue="3.23e-180"
     Typing          complement(16779..19513)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="91.138"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gtgcgggcgg gtgtgactga taagagtctc tctctcaaat cgtccgtatc acctacgggc
       61 gtagcaaagc aaagcccctg ttataacgtc gcctcgcgca agcgtcgccg gttcctcaat
      121 cggtggatta agtcgctggc gaccgaagcc gggcgtatca aaatcaaaaa cgaacttcgg
      181 cgccgtatcc gccataacag gtattgggtt aatgaagcga acaagttcgg gcttgaggct
      241 ctttgcgaac tgatgttggc catccttgac gatctggatt taagggactg gcaaaccata
      301 cataaccttg aaactctggc cgaccgcgcc ggacttgcga cgcgcagtga tgcgggtcat
      361 aagtcgattt cccgtgccag ccggggatgt gatcgcctct cctggctcaa tgccatcatc
      421 tcggaaaaag cccctttcaa cccttatgac gcccgttgcg cctgcaagca catcgaggtt
      481 acagaggatt tctttgccat tctcggcatc ccgctaaaac aggtttaccg ggaacgcgcc
      541 aggctgctta aggccaaccc ggaagaaatc attttctccg gcgatgtccg gttaatcgct
      601 atcaaggtgg agaactggac gcgtaaggcc gctgccgggt tagccaggat gaaggcgaag
      661 cgtgaagtag ctcgccaacg taaacgagaa tactactccc caacctttgc ctgagcctcg
      721 cctactaccg ccttagctgg cggggattct gcacgtctgc aataaacctc agtacaaaaa
      781 acagccttaa cgtacaataa tttccgaaat ccaaaccatc ccacctatcg gaatgacgga
      841 tttttcggcg gttccggcgt agcctcccca caactgctgt atagcttgtg ggtaagtgat
      901 aatgaagtgc aaacgatatg gcgcaattac tcttttggtt tatcttttaa ttacttacgt
      961 attaaaagat aaaccaaaaa acaaaagaca ttactgttat ccccttcaaa aagtggataa
     1021 ccgaatagca tcggcgcaag cgcctcaaaa gtagctcccc acgctaaagc gcggggcatt
     1081 cagatcggaa tcgtgagagg gctaacagct tgcctgttag ccgtcgaggg attggacaaa
     1141 tccggccacg ccggatgcgt cagcaaatat cgctaaacac tttgctaaca cgctcgtaag
     1201 cggctctcac gacccgctaa cgcggagata cgccccaact gcggcttcgc cttgttgtga
     1261 ccactccgac cgcgcacaga agcctctgag ccgcttttag cgggggatgg ctttgcaggg
     1321 tgaagggatg gataggcgat ccctttcgat cactcattgg tatcggcggc taaccctccg
     1381 tgctacctgt catttcatcc tgccgcctta catgcgctga cgcgcatcaa cccccgttcc
     1441 ttcctcagtg gaacgaaaac tcacgctaaa cacgaaggct acgccggaag cccagatttt
     1501 tccgctacat tggatttttg gtgttatgct acgtctaatg agccgtgttt attacacgga
     1561 atttgacgcg aggtatttat ggcaacaaca caacgagcaa cacaaagcgt tactatgacc
     1621 gtagaacgtg ccttactcag ccgtgcgcgt gaggctggta ttaatctcag tgccactctg
     1681 accgcagccc ttgacgctga actacgccag tatgaagcga aaaaatggca ggaggaaaac
     1741 aacgaagcgc tggaagcgct taatcgtttt cacgatgaac atggttgttt cagcgatgag
     1801 tacaggacat tttaaaaaat gcagttcact gtatacagta acaccggaaa gagcgccgtc
     1861 tatcccctac tgcttgatgt aaccagcgat attatcggcc agttgaaccg caggattgtg
     1921 atcccgctgc tgcctgttga aaagtaccct ggcagcactc gcccggaacg gctggttccg
     1981 cttgtcagac tgaacgacgg taaagaatat gcagttatga cgcatgaaat ggcgagtatt
     2041 cccgcccgtt ctctgggggc tgtgttctgc gatgcttccc ttcatcgtac ccaggttaaa
     2101 gccgctattg attttcttct agacggtatt taatcccacc ctccggggct gccatttttg
     2161 tttcggctag ccccaaaatt tggttcgcca aatgcctttt atgttaaatc gaagtgtttc
     2221 tatacaaaaa gagtcatctc aagccactaa ctatctgaaa atgcgttttt tatatttttt
     2281 atgtgcagtt tatctataaa aaacgcatgt aatttttttg ttaaatttaa acacccgcgt
     2341 aacattttta acattttatt tttttagatc ttttttttca ttacctcgat aaaactcaac
     2401 ttttcagaaa agcgctttcc ctgaattagg catgtatcaa atctcattcc ccgtcatcaa
     2461 gggagtttat ataatcggct atgatatccc catgacatgc atatggcttg caatgacacg
     2521 caataatctt tcccttaaga gatgatgcat ttttatcaat attatcaaag ggttttaaaa
     2581 attctttatc aaaatcatat ttgaattttc ttattacttc atccctatcc ccatctacgc
     2641 ctatttgata aggatttccc catatcgtac ctctgcctat atatacatca aatttatcac
     2701 ctctgtcttt attgacaacc agcgtcagat ttaaaagtac aacttttact tttgcattct
     2761 caggtaattt aaaatcacca atatcttgac gtttgtctct aaaaatgatt gcatattcag
     2821 catcttcggc agaattcacc tcacgaattc gaaattgctt atcttcagaa atttttctga
     2881 taaatcctct agggtcagag atgaaaatta tctctgatat gcttattttt ttagtcaaaa
     2941 agtccaattt ccttttgaat ttactaaagc aattgaactc tttactatat tctaaaaaaa
     3001 gtacactcat agtatatgat tgatatcagt tttttggttt aaccattgtt gttttaaata
     3061 ctctgccaaa agtcttctat ggcaattatg tggcttatct tcgctgcaaa gaaggcatcc
     3121 attatccaca tcaacactag ataacttcga tgatataagc ctttgttcca taagatttaa
     3181 gtattcatat gagtactgtt cccaagtgat gtttttattt ttataatcat ctagaatttt
     3241 ctttgttggg gctaactctg atctgtatac ataatctatg ttacatatct ttcttaagaa
     3301 gaactcaaga tcttttgcct ttgcaaaacc ggaaagctgg gaattgttat tcaatcttgt
     3361 atctattact cggatgacgc catttttctt taatgcgtta aagaaatgct cagctgtctt
     3421 ttttgtaaaa cctattgtat gtatatttac atgttccatc taaaatactc cagctactac
     3481 tttatataag tttccattca gtggttcggc tagactgata gtaagatagg agactccatc
     3541 aagttcttcc tcttcgccat cattcaacct gttgttttca tctctgaaat agttctgtat
     3601 tcccatatct gtagtcgtta gtaagtattc attagagtta taggtgaacc ttattctcag
     3661 tttatcagta ccatactcat tctgcatctg tactatcacc gtatcatcag gcttgatcag
     3721 gtagagtgaa ttgtttacca cactctgtcc aataatgatt ttgtcattta caccgtagtt
     3781 actgcttgtt cctgtccccc atagagttgc aggcgtatcc acataatcat ctaaatcatt
     3841 agcagcacaa tgcccattaa cagtaaaact cacgttttca tcaatgatgt ggttctctgt
     3901 ttggtgtcct tgaggggcat ggttaatggt tgttgcttgg aaaaaatcta ggggtttgat
     3961 ggcatttcca tgatggaata tagcgttatt aataggattt gctgtaattg ttcttaccca
     4021 ttgattatta tcattttttc ctgcaatgca aaatcctcca tttttccaag atttagcaag
     4081 acaaagtagt tgatgagttg ttctcatttt cttcccttac atttttccat tagaagccgc
     4141 taggcagaac cttaatcatt gctacatata tcagatctat cttacttttc aatctatatg
     4201 taacaaagtt ttacatggat tctgattggc ttgttatcag tggcctccat gcacacatcg
     4261 aggggagggg gggtattatt atatttttat ataaaaatat ttactgatga tgaggtctgg
     4321 attagactta cagtattacc tatttttata ggaaaatatt tatatagggg atgatatgac
     4381 tgctgttatc gcactggcta acgggaaagg cggggtgaaa aagtcctcga tgtcacgggc
     4441 tatcgccact gagtatacaa aggcaggatg gggggttctt gggctggata tggatattga
     4501 tcaggggtct ttcctggact gggggcaacg taggttgcgg aatggttttg aacctccggt
     4561 gacaattcag ggatgcggga cggtttcaca ggcgaagaaa cagattgaat ccgggcaatg
     4621 ggatttgatt gtcatcgaca gtgcggcgta tgccacgaaa tcgttactca gcctgattga
     4681 tattgtcgat ttgctggtac tgccgacagg gtttagcgtg gacgatctac gaacgaccgt
     4741 tacgaccgta aacgcgctgc gtaacaaagg acattcgaca gataaaatgg cggtggtgtt
     4801 tgcgggggta agtgaaagtg agagtgagta tcgtgcggcg ctggaatacc tgcaaccctg
     4861 cggcgttccc gtcattccgg gcgctattcc ttttctgaca tcgttcagcc aggcgcagga
     4921 taaagggctt gctcttacgg agtcgccttt ccctggccca cggcagaaag ctgatgatgt
     4981 tgtgcagggt gtgatcgacc gactgacaac gcttacgcag tagtatataa taatataatt
     5041 atatttatct atgaggtgat attatggcga acgtcccagc aaaaccgcgc aataccaaag
     5101 gtgagccgcc aagccaggcg gatacggaac acggatttaa tcctacccgg aaaagtgctg
     5161 atggccgtaa ggcacagctt aacttataca tcgatatgga gctgaaacgt gagttccgct
     5221 ccattgctgc ggccaatgat atgaaacatg gggagctgtt cgaggcgtac caggaattct
     5281 ggaaaaaaca tcattaagtc acccggtatc ccggccactg gccgggtgat accgtcactg
     5341 aacgtagctc tgccacttat ccagtattct tttttccaga tcgacgtaca atccgcctct
     5401 gaccaggaaa ccgaccaggg caatagctat caatgcaacg atggcttgag cgcatccctc
     5461 agtaaacgat tccggcaggt tttggcctga gtgctgcatg atgaggccga gtccgaaata
     5521 cgtaagaaag gtacaaacaa agccaatcat tccgattctg gcgatccatt ccgccacttt
     5581 gaatgaccag tatttcaacg gcatctcccg tttaatgtca cgaataacca tagtgtctat
     5641 cttatgggtc agtgactgaa atttagcgaa tatcataagt ccctcgtccg tctaaaaatt
     5701 aaccttacca tatcagaatt atataaaaat ataatcctat ttattctgtt tgcgccactt
     5761 ccacggctcc actggatcag gtgacgacca cagcccgatt ctatggcgtc tggcttcttc
     5821 ttcaaggcgt agcattgttt cgtcactggc acggccatga tagcggtaag cccacgccat
     5881 acccgcttta acctgctctg cgttgatatt gataccgcca atcatcagtg ttcccagcca
     5941 gcggccataa cgatctgtat tgttggctat gacctccgtc tgtttctgga cggccagctt
     6001 taacaagttt tgcttcgagc gctggccgaa cggttgcccc gattccgggg catcgatacc
     6061 gttaaggcga actttcatca ttttgccatc ggtgagtacc tggacagtat caccatcgac
     6121 gacccgaaca acacggccag aaaagtcagc caggcaaagg gcggggaaaa gcaggggcag
     6181 aaaaacaagc aaacgagatc ggcatttcat ctgtcacacc ttataaaaat agatttatat
     6241 aaataatcac tggccgccgc tggcggctgc ttgctccagt tcatcaatgg tgcggaaaag
     6301 aaacatttcg cggtttttcg cgtcgaacgg caccggaacg ttgttcctca ttaccgtttt
     6361 gatggagtca aacagccgga ttaacgatgt tttggttttg tcatccggca tgacatacat
     6421 cgcgtagtgc cagcgtccgg catcgctggc cgccagatgg ctgttaatga tgttgatata
     6481 gcgtgcgcgg gttttcattg agcgctcagt ttcgacggcg acgattgcgc cgctatctaa
     6541 cgtgataatc ccgtcaggac gatggcgaac gccaggataa cgcgcaataa actccccccg
     6601 atcaccatta agccagcctt gcccgccttt ctcttccagt gcaattctga cccgatgatt
     6661 caggagccgg tgttccagcg tccagtattt gagtttcccc ggctcaaaat aaccggggaa
     6721 tactttatca tcaggcttaa ccaccatcgc cagcccttgc atggtgatcc cccatagtga
     6781 tttttttccg gctattaccg ggtattcatg ttttatcaga aaccccaatg caaccgcttt
     6841 attcagtagc gcatacgttg ggcggtgact tttacccttg aacccaacaa cttttttcag
     6901 cgttttaaaa tcggagtatg tttcttcttt aaggaatgtc agcaatgcaa gcatttttct
     6961 gtttgcggct tctttccttt ctgcaacgtt atgaataagc atttcagccc tcacagattg
     7021 attgatggct tatgttcctg actttcattt ttttccggtg tggcttgctt atactcaaat
     7081 gaaagaagtt cgatgttttc ttttttgacc tgaacctgaa acatctttgt agctcttggt
     7141 agttcggttg acgtaaatac aaaaccaact ttttcaggga gatttaaaaa catattactg
     7201 tcaacatagt aactctctgc ctgtcttatc attcggtctg tatccacttt ttccgttaat
     7261 gacaaatcag tccgtacttt cctcatttca tcatcgacca ggatagagcc tgtcattttt
     7321 gccgcccatt ctgctgtttc ggggttttgg attttataaa tcaatttgaa tttggcgttt
     7381 tcaatgatag cgccaataac tgaatcacca tttaaatcag acgggcagtc acgcagatcg
     7441 tctatcgcct gaaaagccat gaatatatgc acgcctttat ctcgtgccgt tccaagtcct
     7501 tcaagagcag ggcgagaaag atgatatttc aactcgtcga ggaaaatagc aacagtacgc
     7561 ggggtgctgt ttattctgtc cctggtctcc gctatttgta tcagccgggt cagaatcatt
     7621 ctttgtgcag aaattatctt ttgattgcgc gttgaaccaa taatgtagca acaaccacct
     7681 tcatcaaaaa cctcttttaa tgaaaatcct ttggtagcat taattgagtt aactaaagca
     7741 atttcttcca gctcaccaca aaatgcggga acatcttcac gtaatgattg aacaaagtca
     7801 gtgttaaata aatcacgaag cgtcattcct ttttcataaa ttgcagatgt atttctggct
     7861 gcgcgacggt cagagatacg ataaaaatca gaagcctccc ctttcttagc caggctaaag
     7921 ccagcgttaa ataattcctc cagttgttca tgagatatat cagccaataa atcaagctgg
     7981 aaatttagct tgtttaaatt tataagtgtg aatttcttgc ctgctttctt acatgcttcc
     8041 ctaagtacgt gtggtgccca ttcatcatct tttggatctt ctacaaaaac agcctcacct
     8101 aaaagaatag cctgataaag tagaacggtc gcagttacgc ctttcccgga acctgttgtg
     8161 ccgataattg ctgcgtgttg ggttttgaat tcttttatag ttatgtattg cggctggtca
     8221 tctttgttta agccaataaa aacgcctttc tttaaatcaa tgtaatcgag tggattatat
     8281 tctatggggt cgggtaatag ctcttttact ttgcgcacat cggttcgggt atttctctcc
     8341 agcttgcttt tcttaatcat tcgatgtttt aggttgtcaa tttctcctgc taaaagtcgt
     8401 cgggctgcaa tatgaaatat caatcctgat gccgtaaaca ttatggtcat gaaccataga
     8461 ggaactctaa acaatatgtt gttgtcgagt gacttaaaaa agtagctcaa cccctgaata
     8521 gttagcggtg atatggtgcc gaatataaaa aagaaaatgg atacgcacgc caccgacttt
     8581 aaccagaacg gggcgttctt tctttcctcg cggggaaggt ggaatataaa aggtaatgta
     8641 agacctgcga gcagggataa tatgacaggg ctgttttgca gccataacaa aaagaatgaa
     8701 aatgcatcgg caaaggcatt cagcctttgc atcaggtggg aacccatatc tattttctcc
     8761 atacgaaaac tgacgtgttg ggcgcaaaag atgggagcag cttataggag cgtaaccacg
     8821 ctcccatgcg atgctcccat aatatgctcc gatgaacagg caaaaggcac tgatcgccag
     8881 tggcgatcaa gcccgttatc cgcgctttca gaatacagcc gaccagtggt cgtctgtcct
     8941 ctgaaacgcc cgaatgacgg gcaacggctt gtgccattac gttcgggctg gacgccctca
     9001 ctgcatgaca catgggggta atgtcccggc tgaacgccga gccaaaaccc ccaaggtcaa
     9061 aggcggcaca ccgtcttgcg ctacgcgcga ccaacccctt taagacgctg cgtttagcct
     9121 atttttcctc gcaagctcga aaaaatcgga acgctgcttt aaaggggttg gtcgcgccta
     9181 atcggtaata tcccccgctg gggcgggtta tattacctgg ctgcgacggt gtgcggggca
     9241 agccccccac aaaaaacggc acgtgggcgt gcctttttgc tcgctggggc ggcaaaattt
     9301 ttgcggctcc ccccggcctg ctcaattcgc tgtgggcgaa tgttcgcagg tgggcgcggt
     9361 tcctgaaaat tagcaatttc ttcgaaattg aattttcttt ccgcgtgcca cttcatgatt
     9421 ttacgtctta acaatttctt cgaaattgaa gccaaaaata atgaagcctt aaagtcccgt
     9481 cgcctgttag tctgtgtagt gtacaataca cttttgtttt gtgtgattac atttgctcgc
     9541 ggtatatttc agccctgcac tccctttcag cttccagtgc ttcactgtag gacgcatcat
     9601 caattttcgt gcctttgctt tcggcatagc gtcgtaattt atttgcgtca gcttcattaa
     9661 gttctgaaag atgatcgcgc aaaagaccga taaaacagct ttcgtatatt tcgtaataca
     9721 gcccacaacc tctgtgggct tcttttgata acgtgtcata taccagggct acagatattc
     9781 tgtcctgatt ttttgagtgt atattcttaa tgaataaatc ttcgtttatc atttcgaacc
     9841 tctcatatca aaatggatat gtcagttatc ctttcactct gccaaatttt gaaaggattt
     9901 tgcttattga ttcagggtct gcggctttgc actcccctaa aaattctttt cgcatatcga
     9961 atgttttacc cggattaaaa cgatggtgtt ttttaaatgc gttgatttta aaaaatgcgc
    10021 gttctgctga actgcattca cccccaccac tattacctgt ggcttttccg tacatgcaaa
    10081 gaacaacttc gcacgggtca gcggcaaagg aataaatcgg cgttcctgcg gtcaggcata
    10141 atacagccgc cgcgataacg gtttttttca tgataaatcc ttattagatt gtgttgctta
    10201 aatggattag cgagagaaat aaatagtggt ttctctgcac gtcaggcaat taaaaacagg
    10261 ctggtattca ataacgcctt ttgcgccatt ctggcgaagc cagtttttgg cattaaagaa
    10321 atcagtgccg gattgtgcag tgacgacaat tcgtgttgaa tgggcgactg cgtaaaatac
    10381 tgctggagtc catattgtat cgtagaaact ttgtgcgctg attgatgatg tccatttacc
    10441 gttaactgtc ggggaaggga ctataatgtt attatcactc cattgaggta aactggtatt
    10501 taatgggacg gcggctttat cccactctac agggacggga ggcggtggcg atgaacatcc
    10561 ggtaactatt gccgccaaca tgattacttt aagtttcttt atcatgcttt catttcctca
    10621 aaatattgat ttcgatggat tggacggaaa taaatgtcat tcatacggcg aacatttccg
    10681 tctaaatcaa tgctcacaat cacgtccagg ctatccagaa ccttacgtaa cataaatgta
    10741 taggggagct gggcgcactg tggattttca tagcaacggg taataaaccc atctatagct
    10801 tctttcgctg atcctgcatg aatggaggtc atactccctt catggccgga acctgttatt
    10861 ttgaggaagt cccaggcttc cgcaccgcga acctctgtta ataaaatgcg gtcagggttc
    10921 atacggtaat tccagcgtaa aaggctcgcc ggggtaacga tagacccttt ttcatctgat
    10981 gattctgacg gataaaaaag atggacgtag tttttatgga taaagaacgt gatttccggg
    11041 ttgtcctcaa tggttgatat ccgaagatgt acaggaatat accctatcaa cattttcata
    11101 taggtggttt tcccggtact tgtttccccg gcgaccgcga gcgttttacc gtactcgacg
    11161 catttctcca taaacagagg aatatttttt gtattgtaca atgcaattaa ttcctcgtcg
    11221 tgcgtctccg ttttttcctc gcctgttacc cggttataaa atcccgcatc gatatacgac
    11281 tgatgcggga tttgtacctt tgatggctta cggatggtga tagacaccgt atcgcgctca
    11341 caggccgggg gaacaatcac ctggcaccgt tcgccagatt ccagcgtggc tgacagcccc
    11401 ggcttaatat cttcgatatt gtcgccgtgg tgctttgcca ggcaccgggc aaagttgtag
    11461 caatcctcat aggacaaagg aacggcgtgt tgctcccata cgccgttgat tttggtatac
    11521 agctcacctg gacggttgac ggcgatctcc gtcaggccgg gaagctccag aaagtcgcca
    11581 aagaaacgct gtttatagcg gtcgagggaa atattcttag cggtcatttt tcaacctcag
    11641 tgtatagatg ttggaaaaat caatatcctc acctgtgatt aggttgatga tctcgccctg
    11701 attcttatag agcgttgggg gaatattgat gctgttctcc agcgtagtac gcgccatatc
    11761 tgccatagcc tggcggctgt tttccgtata gtccgtattg cggtcttttt tacccgcgct
    11821 gttggatgcc catgcgccaa tatcggggat catgccgacc attaacgcgc cgccgaaccg
    11881 ttcccagaag tgcgaatcta tccagccatc aacgccagcc tcgcccagct cgccagccgc
    11941 gctggtatca accagcggga tatcgagata aggcgcctgg cgggtgcgta gcttcgtcgc
    12001 aatgatgaat gcccgccctt gcccgtgctt cataccttct tccgctatgg cgcggtaaag
    12061 taatgatgcc gtggtgcctt tctctatcag cttcgtgttg ccgctggcgc tccagatgtc
    12121 agtagtgacc gtgcagcgaa gtttccccgc ccggtcagac acaaagcggc gatccagtga
    12181 gcaggggatc gaggtatttt ccgggatgta caggtcaggg ttatagggta tgcggcgcac
    12241 tggtgcgggg ctttgtcccg gcgacggtga ggcggtattt gtggccgcgc tgctgtcctg
    12301 ttgtccggtg gacgttgccg atgtcagcgt catttcctgc tgccgggttt ttaccgggtt
    12361 ctgtgtggtg gccgaaccat cacggcgaat aaggaagctg gctttattga gttctggcgg
    12421 ggcggccgga gccgcctgcc ctgttccccc cgtgctgctc tggccgttat cctgttgctc
    12481 tggctcttct tcggctgtat cggtggacat accgagatcg ttacgctgcc ggtaatcggt
    12541 tttgttcgtc tgcggggctg tgtcctgttt cttttcttcc gtaggttgcc acaggatatt
    12601 gcgataaacc cagttccccc cccatgccag gaagataagc gcgaccgcga caatggcaag
    12661 aaaggcggtt gctttgcccc gtttgcgctt tttcagcttg ttaacggcgg gttgtaccgg
    12721 gtctttctct tcgtcgtcct gcgcattgag aagcttggcc tcccttttag cgcgggcttc
    12781 ccgctcaagc gtggcaatat cgtcctcagc gtgtgccggg gatgcctgcg cttcatccgg
    12841 cacaggcact ttgttttcgt cgttcatatg cacgtttcct tttataaaaa tataaaacta
    12901 tttttatagg ttaattggat tccggttttt ccactctttc cacctgccgg gatacggtgg
    12961 aaccatcggc ggcgtgtacc ttgccaaatc cgctattttc cagacccaca acggcattac
    13021 cggaacgcag tactaggcgt ggcgtcacct cctgaatcac cagtacggtg aagtcgcctt
    13081 tcttttggat actgctgtta accacatgct ctttgccgtt cagctctttg gtgacggaag
    13141 gaatggactt agacggggag aagcccacga acgtaaagcg gccatcgtcg taagcaaaat
    13201 cgggaacaat gttgaaactg cctttgcccg gatatttggt gtaactccag ttgcggggcg
    13261 tctgcgccga gttcagcgct ttctggacgc tggcatgttg ctgtttctgc tcccactcgc
    13321 gctgtctggc cgtcgcctcc cggctcgctt tgtcccgttc ttcgcccgga tagcggtagc
    13381 tcacctggaa agcgggttgt tgtgccgatt tatcatcgat gacgttcagc tcgacgttgt
    13441 acaggcgctt actggtgaca accagcatat tggtatgcca gtcccggctg ttcgggggga
    13501 tcacgacctg cgttgtgttg ccatcttctc cgggcgctcc ctgcgtgagc gcgaccgggc
    13561 gaacgttgac ccggtttgca tccggcgtgg cttcccacgc ctcatcaaag ccaggtttgg
    13621 cgcttatgac cgcctcatcg ttatcaaaga ccagcgttgt cataaagccg ggtttggtgt
    13681 taacgacagt gacgttctgc gggttataga taacctgctg cacgcgggag tcatagcggc
    13741 ttgcctgcgg tatggccgca ccccatgccg cgccgcacat catcagtgcc agtgcggtaa
    13801 acgttaactt tttcatcatt cacctccccg gatttcgcgg tcggtctgcc aactggtgac
    13861 ggtaaagccg aagtagttga tctcgcgttc cgcatcgctc atttccttgt cagggttaga
    13921 atggaacgtg aaccgggcat cccaatattc gttgcgggtg ctgttatcag ccagacggcg
    13981 gataatcttc ttgtagcgga tggtggcgac cctatcaggg gctgtcgcat cggtgatctg
    14041 gttggacaag atctccactt tcacggtgtg cgccccgttc ttataaacct tgtccggggc
    14101 gttttttccg gcgtaaagcg ccaggtagtc atcgtttacc tggggagcgt tgtagacctg
    14161 taccgtctcg tagtcgtcct gcaaagaggg atagacatac cgctcacgca ctttgacgta
    14221 gtttgcggcc attgcctttt gataggcttc tgttgcggtc aggctggttt tcgatgtccg
    14281 ggtaacgtgt tccacccgtc ctgtgtggtt atccacggta tacagctcaa cgtccgtctg
    14341 tttcagcggc aacatcacga ccacggcgac gagcgccagt accgcaatca gcagacccac
    14401 accgccaaca acaaaaccgg cttttgtggc gcgtttatcc cgctcaatca tttgctgctc
    14461 aaaggtgcgg gattcagcta ttaatttctg ttcactcatg actgtttaac tccgccataa
    14521 tttgaggggt gtttacgggt tctcccttac cgctaaaggc agagggaggc gtgttctggg
    14581 cgcagccaga aagcgcgcac agcaaagcca gcgcaatcaa gcgtttcatc aaagatttcc
    14641 tcaattgaat tagaaatatg aaaatataat tatattttca taggttggtg tttcgggggg
    14701 atgtactgga aacgtctggc ctagctgttg aacttcttaa ccgcggaatc tctcgactgt
    14761 gccagcctcc gcgcttcgtt ccgggctatc atctgctcaa tcgcgtattt acgcgcttta
    14821 gaagcgttat agcctaactc acctccgggc ttgccgggct tacctgcatt cgcatccttc
    14881 cagccctgaa tgttgtcctg ggcggaacgt ttggtttctt taactgctcc cccggccagc
    14941 ttcccggcac caaaagcagc agcaccgata cctacagcgg ccagcccctg catggatacg
    15001 gtagcactcg ccccggccag tgctgcggcc agttttgcgg agagataaat caatattgcc
    15061 gcacagatac ctgcaagaca gacttgcgct cctagctcta cgatatttgc ctgggctgca
    15121 ccttgagttg ctaatgcaag ccttgagttt aagtaattaa ccacaatcct taatgataaa
    15181 gaagaaagga gaattgttaa tatggctgca aatatgtttt gtagccagtt attaaacatg
    15241 gggcgaagga aaccatacat aaggcaaaag atgaatatag gtgctgtaat actcagcaat
    15301 aagatcatta cttccgctat catggaaacg aatgcggtga taatcattaa aacgaatatt
    15361 ccaagccata cataaaattg agcagtcatt ccctcatctt ttatatatgt ggagttatcc
    15421 atatcatgta atgttttacc taatactttt gcattattcc ataagctatc taatagctgc
    15481 catatgttat cactgccaga aaagccctct tttaacccgt tgatagcgtc gataacgcca
    15541 tcgagataac cactaatatt tgccacaaag gaaaggatga tcgccatcct catgatgtcc
    15601 cacatcgtat cttccatcgg cgtggatagc ttacccgcta acgtctggta tccacgccac
    15661 atgatgtaga tagtggctga cgtaaccgcc agccccatca tcatagaaga gtacgacatc
    15721 attaatccct ttgtggcgtc cgttattcca cctatcaggt gcttttcaac accaacaaaa
    15781 acaccaccgg acatatttac ctcactatga atttaaatcg acagtcggag catttaattg
    15841 ctgaatttgc cagtgagctt cgttcgcatt tttacaattt tccgaagcgc tccctgtttt
    15901 ttgacatttt tcgtaaacag cttttagttc ttctggatgg tctttatacc atttggtggt
    15961 tttagcctct tctttgcacc cactaactaa gaaaactgat aatgccagga gagatattgt
    16021 taataaacgc atgttgtagt tccctttagc tatttaaatc aactgttggc gcgtttaact
    16081 gctgctgatt ccactgttta acgcgctccg cctcaagcac tttttcgcgc ttctctgctg
    16141 ctttcacgct catttcccat tgggtggtaa gcgtgttcag catgacagat tttagctgaa
    16201 tactgtttgc aaggtcttga gattctttcg aatctttggc taacgctacc ctgttggaga
    16261 ggctgttgat ttcccctagg gtttggctta cctggttctg gatttcgtcg gtctgctcaa
    16321 gctggatagc tttattgata acctgctgct tgcatacgtt ggcatagttc cccgaccgtt
    16381 cggcattgca ggtatcgaat attttgtact tctcatacag cgcgtcgaac tgtccggagg
    16441 aaccaccgga gagaagcaaa tcattcagag cctgtcccgg cttgcgtagt ttttcgagat
    16501 cggctttcag gcttttggcc tggtcaacaa agctggcgat atctcgaaca cctgtggctg
    16561 ttgccagttg gtctttataa gctcgtatct ggtctttgta gtgttgtgcg gtctccatcc
    16621 attgcttggc ttctttctgc cactgacgga cattttccag tttggctgtg gcatcaaata
    16681 ctaaaatacc tcccgcttgt gccagagggc ttgcaagcga acatgcgaaa atcagcgcgt
    16741 aaaagtgagt tttcatccta tatctccttt ggaatcagag tgctttagcc aggtaggtat
    16801 cgagccattc atgaggctgc attccttccc ggtaaatcga ttcgaatatt tcgaggttgg
    16861 gggcatcgcc gctcatgact ttggtgtatc tgccgatacc cgacaggtcg agcgtgacac
    16921 gagcggcaaa acgtttggta tcgccgcgcc tgaactgatt tttcaccaca acatactggc
    16981 gggcttgcgg gtcaagccct ttcaccacgt caaacacttc tggttcaaac ttcatgccgt
    17041 caacataatg tgcgcggtcg gcgttggggt tcgccgccag aatctgtgtc ccgcactgct
    17101 caatcactgc cggggcgata tcatctttga tgatctctgc cggggattga gtaccgacga
    17161 ccagcatccc gttcagctta cggatggttt tcagcttgtt ataagcaaag tccttaaaca
    17221 ccgggtcgcg taaccacttc cagaattcat ccatgaaaat gactaggcgt cgcccgtcaa
    17281 gcaggctggt aatgcggtac agcaggtaaa acgagattgg cgcacatacg cttgcatcgt
    17341 ccaggaactc cgttccgtcg atgccgaagt tatcgcagtt gctgatatcg aacgtgtcag
    17401 actcgttatc aaacacccag ccgaactcac cgccctgcgc ccactgtgac aaccgaatgc
    17461 taaggccgtt ttcctgggct tctttcgtag ccggctcagg caaattttcc agcattcggg
    17521 taatgccgta gacgcgatat tgtggctcgt cattcatcac agcattaacc gcatcactca
    17581 gacggcgttc atcgcgtggg gagatcgtcg agccgttgcg ggtacaaagg attttcatca
    17641 gttgcttgat gaaattgata ttgcgtttgg ttgcaggcaa cgagaacggg ttccaccctg
    17701 tagactcacc actgataacc cggtagtaac ggccacccag cgcccggatg ttcatctctg
    17761 cgccccggtc tttatcgagg taaacggttg tcagccgttt ggttttggca tccggggaga
    17821 agctatcctc gcgcccgtat ttctgctgca tgatctcaaa gaacgtcatc aacatggttt
    17881 tacccgaacc gttcgtaccg aggatgcagg tactggccgg gttcttctcg ttgaattcgt
    17941 ccttatctgc cagtgtgtta tgcaggttga tatagtagcc atcgcctgac ggggtgcgca
    18001 gtaaagccat cgcatccccc cagggggctt tatcgcgctt gcccggatag aaattatgga
    18061 gtgcggccag ctccacaaag ttctggctac tcagctcccc tttacgtgga cgcaggttgt
    18121 agttgcctgg cagttgcgcc atatatgccg ctgaaagcga tatttctgcc ggaacaggcg
    18181 ttatcccgat gttgttcagc gcgttactga tttcgttagt atcagcaacc aggctttcca
    18241 gcgacgggga atacaccatg atggaaaaat ggtgctttcc gtaagcgatt ttccccgatg
    18301 tcagcaggtc aagcgccaca tccagatcca gccgctggga aacagcatcg tcgtcggcac
    18361 tcatcaaaag gcgacgggta cgcttaatgg ctttcttcgc ttcctcgcgt gacatgcagg
    18421 tataggactg cgtgatcacg taatcgcagg gggcgtaaag aagggagtcc atcatccccg
    18481 tggccgtctc ttcggagaac tctttaacct ccagcccccg gaaatattgc gtaccgttgg
    18541 cgtggtttat ctgcccggat tcagccgaaa agaacaacgc cgccgccccc atcacgtcat
    18601 aggccggggt acgggtgacg cgcacttttc gccactggtg cgttagcaga tattcataga
    18661 aagccagttg cgacgaaaac accgcgtttc cttcggtaaa cgtaccgaga ggccgcgcac
    18721 catagcgcga cagcgcggta tcgagcgtgc tttttatttc cagcatttcc agcaaagcac
    18781 cgtccagctc ctttagtttc tggctgtctt tcatccgttt acgttctgct ttttcaaggc
    18841 tgacaaacgg gcgatagcag accgtcagga acaggcggtt gcgccggaac agaccgacag
    18901 aagcgtagta aagacggcta acttcatcgg catacgggtt gccggaatct ttatgaagat
    18961 tgtcggtaaa cgtattacgg tcgttatgga tatagaaagt aacgggcata ccttcgaatg
    19021 agcggattag cccgtgtaac tggttcgtcc cgaactggag cgattcgtca gactcgcagt
    19081 cgaacggcgt tcccatcaat tcccaggtgc agtacagatc gcttttaggc gagcggacta
    19141 catgctgatg aatgtgcgat gagtacggaa tgtacttctt gatggtggca cactgattta
    19201 gtttcatggc gtcgagaaac tccttgatat caacatcatc atgctcaacg ggcataaatg
    19261 ttgttgcgcc aaataaacgg tttgctaccg gctttccctt cgctctcagc catacggcaa
    19321 tcagattgaa ccgcatcggt tcatttctgg taagggactt catcaccaga aattgcacag
    19381 gaagtaagaa caggagagcg acggaagtcc agatagcaac gatgatggtt acacccgtga
    19441 cagccagcag gggcaccatt ggcacccccc acagcgccgc cgggcgtttc attgccttga
    19501 gcagctttgc catatgttca gcctcttagc tcatcagcag agcgccgatt tcactgcctc
    19561 cgccaattaa aatgccgcca atgatgatgt agccgcactg tgacaggctt tcgcctttcc
    19621 acagggtctt atagccaatc cagatcacgg ccacggtgat cgtgatggcc gccaagccat
    19681 gcagcccgct ggataccttc tccatgatgg tatttgcccg gctaaaacca tcagcaaacg
    19741 ccggactggc agcaaaaacg ctcatggccg gagccagaac ataagcagat gcacggctga
    19801 ttaattcctt taccttactg aaaagtttca tttttcttcc tctttcgttg ttacatcgcg
    19861 atttccgcgg acaacctgcg cggggtaata gatggtggcc gcctttttct ggcggagttg
    19921 agccggaacg ccgcgaacga ttgcacccgg ccacaccacg cgcgggcgcg tcggcgcatc
    19981 cactggcgta gctttcaggg tggccgctgg ggttgcgata tcatcgcggg tgccgggaac
    20041 ggcatagcgg gtatccgccg gggaatagcc aatccgctgt acatagctcg tctttgaaaa
    20101 agcgggttcc tgctgttgtc cggtactgaa attgccggag tagtagcagc tcaacgccct
    20161 tttcagggtg ccgccccgct ggtagcagtc ggtgatgatt ttttcgtaga cggaaagatt
    20221 gatgcaggga ttgaaaaggt cagtggcggt gacgccgtaa cgcttgaaat tggtgctggt
    20281 tatctgcatc aggccaacag agtagcggcg acctttcgcc tcaatctgat tagtgatgct
    20341 gactgcatcc tccttacttt ttggcatgtg agtaataaag cctttatcgc cgggttttcg
    20401 ttcgggctta ggcacgatct cagcgatggc ataggggtta taaccagact ccacccttgc
    20461 cacatcgagg gacgtagaag ggtgaacggt ggcggcacac tgcatagcca ccgccagaaa
    20521 agcagtggtg gaaagcatgg caacctcaga acagaaaaat ggtgatcagc cagatgatga
    20581 acagaacgaa caaccagcca gcgaacgcaa gccaggcatt gggattgtct cgattcattg
    20641 tgctgtctcc ctgttttaac tgacaggagc agcctgcggc gctgcgtcat ctttaggttc
    20701 gaggagtacc agcttgccgg aaacggaaat accgggcgtg atcatgatgt tcagccccga
    20761 cttgccgttg tgtgcgaagg ccgcaccgac tttcgtccag tacgtatttt tttcgccgtt
    20821 ctcgtcgggc tgggtttcct gcgtgacgta cacgttatag gtgggttttc tcattgcatt
    20881 actccttttg tttctctgag agtagctgcc ggagcagctc agtacgggct tgctcaccaa
    20941 attcatccat caggaactgg agaaaggtgc ttggccggat atttgattca gacaggtagc
    21001 tgatttcacg ggcttgcttt gctaactcct gatagcgctt ttgcccgatg taaataacag
    21061 ccgtgcttga tttgcctggt acgcttttcg gcatgaggta aaaactccta tgaaaaaagc
    21121 accgcagctt atgaagccta cggtgcaagg gaggtcaggt tgtggttagt ggtattggtt
    21181 ctggagtagt tttgaaaagg ctacctggcg ttggagcgga gaccttatca gagagagttc
    21241 ttgaattttt gccagcaaat tcggggcgat atttcggcac tcgatagcat cttcatcagg
    21301 attgagcgcc atcagacggg cgcattcaat cgctgttatc actgatttgg ggacggtgca
    21361 gggtgttgaa ccgaagctga caaaaccatg agcgcccgga atggatgtga tagtcgatgt
    21421 atgcgttatg ttgacgtcaa agcagaggaa aagataattc ggaaacaacg ccttttcttc
    21481 ctgacgtacc gcccggcaat ccttacgtgg cgttactttg atatagcggg ggcaaaacac
    21541 ctcgacatcc agtccctcga ctcttcgggt gatgcgttca acatcctgat tgttgcagta
    21601 taaaacgtac cattcataca taagatcctc cctaatgggc acaagccccc attttccgcc
    21661 gtcctaagtt ggcggaactt agagcgcgta ctcatagctt aactgtataa atttacagct
    21721 ggtattttat acagtcattt cggggtgtca acatcaagaa ctactaatga taataacatc
    21781 aatgttcata tatgcaatac gttttgaata tctgtactca cgatgagcag cctctatgta
    21841 tgttttgaaa aacaaaacaa ggtgataggt catggttcca aaacgtttga aggaagcgcg
    21901 agaggccgct ggtttatccc aggaaaaatt atctgaactg gtaggggtgg aaggggtcaa
    21961 tcctcggtca aggatgtcta attatgaagc tggacggttt gcaccaccgt ttgagtttgt
    22021 atgccgtgtg gctgatgtgc tgggatatcc agagtattac ttctatatag tgaatgacgt
    22081 tacagcgaaa cttcttctcc ggatgcatag aggagaacag aatttgcatg aagacattga
    22141 gtttgaggca aaaaaaatgg ctgaacagct tgaagacgca agaagactgg ttgctcagct
    22201 cactgaatgc ctgaaacatc gcccgtaaac ctgccgcgct tcgcttgtcc aacccctgat
    22261 ttctacacaa aaaatttgcg taaaaatcag gggttacgtg ttttaaatag atagggtaac
    22321 gatgggagga tgatctatat ttatagtctc aatgttattg agattcatac aactttatga
    22381 tttttggtaa taaaatagag tagttttttg cgagatcttt ggcgagataa ttgatcctaa
    22441 tgtaacgtcg tggtaattta ccgacgttta cagtattcat gcgggtggga cgttcccggt
    22501 aatagcgtcc agggatgggg tgaagcgaaa gctcaacccc tgaatgcaaa aaccccctga
    22561 aatctgcttc aacttggcgg gagagacaga gatcaggggg tccaaaagca ggcgctggcc
    22621 tgtgaaggat tatagcaaat gcataaccta acacaacccc tcagactcgc cataa
//
