LOCUS       NZ_CP110120            33826 bp    DNA     circular CON 25-JUN-2023
DEFINITION  Escherichia coli strain 2-331 plasmid p2-331_3, complete sequence.
ACCESSION   NZ_CP110120
VERSION     NZ_CP110120.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN31436521
            Assembly: GCF_030012585.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33826)
  AUTHORS   Grevskott,D.H., Salva-Serra,F., Moore,E.R.B. and Marathe,N.P.
  TITLE     Complete sequence of a new conjugative multidrug-resistance encoding
            IncFII/IncFIA/IncFIB plasmid carrying NDM-6 metallo-beta-lactamase
            from pathogenic Escherichia coli sequence type 167 isolated from
            sewage in Norway
  JOURNAL   J Glob Antimicrob Resist 33, 291-293 (2023)
   PUBMED   37086893
REFERENCE   2  (bases 1 to 33826)
  AUTHORS   Grevskott,D.H., Salva-Serra,F., Moore,E.R.B. and Marathe,N.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2022) Contaminants and Biohazards, Institute of
            Marine Research, Nordnesboder 3, Bergen 5005, Norway
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 06/25/2023 10:51:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,128
            CDSs (total)                      :: 5,009
            Genes (coding)                    :: 4,738
            CDSs (with protein)               :: 4,738
            Genes (RNA)                       :: 119
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 271
            CDSs (without protein)            :: 271
            Pseudo Genes (ambiguous residues) :: 0 of 271
            Pseudo Genes (frameshifted)       :: 88 of 271
            Pseudo Genes (incomplete)         :: 181 of 271
            Pseudo Genes (internal stop)      :: 59 of 271
            Pseudo Genes (multiple problems)  :: 56 of 271
            Pseudo Genes (short protein)      :: 4 of 271
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP110120.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..33826
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="2-331"
                     /isolation_source="Sewage"
                     /db_xref="taxon:562"
                     /plasmid="p2-331_3"
                     /geo_loc_name="Norway: Bergen"
                     /lat_lon="60.39 N 5.32 E"
                     /collection_date="2020-08-05"
                     /collected_by="Insitute of Marine Research"
     gene            join(33229..33826,1..311)
                     /gene="virB9"
                     /locus_tag="OMD12_RS25390"
                     /old_locus_tag="OMD12_25205"
     CDS             join(33229..33826,1..311)
                     /gene="virB9"
                     /locus_tag="OMD12_RS25390"
                     /old_locus_tag="OMD12_25205"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_001299943.1"
                     /translation="MMKKLFIATCLLLPGLVYSAATPLPSGFDARMQTVSYNGANTTVI
                     RSKTGFLTSVVFDEGEAVISAKAGFPAGWEITTDDNVVYINPRPVVQEQEGDEGEKLKK
                     VFQPTEKEWDTNLFVRTTKRIYSLDLILLSEEKQAQPAYVVQFRYPSEIAKKNAEEVRL
                     AKEKQEKLRQKKLISESFEKADAPKNWDYFMRVNEKYDSRRIAPDFAYDNGIFTFLGFN
                     SGKVFPAPFAVRDGQEQTLAFNVETKGKYKIMVIHNVNDKFVLRYGNSVVGVVNKSFGK
                     VLTDQRNTSSPAVERVEVNND"
                     /name="virB9"
     gene            304..1422
                     /gene="virB10"
                     /locus_tag="OMD12_RS25395"
                     /old_locus_tag="OMD12_25210"
     CDS             304..1422
                     /gene="virB10"
                     /locus_tag="OMD12_RS25395"
                     /old_locus_tag="OMD12_25210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_000131271.1"
                     /translation="MTDMKKTDDLVDDANQSKLESKPVHDIGDIRNKNNRMRSGFLFGL
                     MAVLVIGIFALKTYKNYFADDQQKASESTGDTSISQVSKIRTGLGQNFDPVENKAIINP
                     GATGSGNTVSDGHKEVPQEGFRKYLSIPVAGQGGSQTGASGSSRTSQTSEPQEERKESK
                     ENVPGKSGMKVTAINLDPDLYIEENRLIPCALTTRFVSDVAGRISCVFTEDVWSANHHT
                     KLLEQGTKAFGRYQTGTLNHGQGRMFVMWEQLRTPDNKRIDMVNTAAAGPLGEAGIDGW
                     IDSHFWERFGGSLMLSMVQDVAAAAADNAPGKDRNVDYTENSRQAMAEMAKVALENSIN
                     IPPTMYKNQGDIITIMVGEDIDFSDIYELKVK"
                     /name="virB10"
     gene            1424..2452
                     /gene="virB11"
                     /locus_tag="OMD12_RS25400"
                     /old_locus_tag="OMD12_25215"
     CDS             1424..2452
                     /gene="virB11"
                     /locus_tag="OMD12_RS25400"
                     /old_locus_tag="OMD12_25215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401678.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_000017224.1"
                     /translation="MSGVIPVSISNKSLDFYKNQVFQSFLDIEGLTEIAVNRPGEIWTE
                     INGDWTFHNNDGVTFDFCKRFSQTLASFRGDEIGDTKPLLSATLESGERVQVVFPPACE
                     RNTISITIRKPSTRQITHKEYVANGFYDYVQSGKKHRTYDDELLDLFRARNIAAFMELA
                     VAAGKTIVFAGATGSGKTTYMKSLIDFIPLNTRLITIEDAEEIKFFIHKNYVHLFYPSE
                     SGSDSGSIITAAKLIKSCLRMKPDRILLAEIKGGDAWDFVKVAGSGHSGSMTSIHAASA
                     KDAIIQMVTKCYQNRECQNLPFDVLRKIIMDSIDIVVHVGRDGVVRHMSDIYYKGAECE
                     NF"
                     /name="virB11"
     gene            2439..4301
                     /gene="taxB"
                     /locus_tag="OMD12_RS25405"
                     /old_locus_tag="OMD12_25220"
     CDS             2439..4301
                     /gene="taxB"
                     /locus_tag="OMD12_RS25405"
                     /old_locus_tag="OMD12_25220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxB"
                     /protein_id="WP_000847103.1"
                     /translation="MKTFNKSQSVFIFAVMLVAAWFAGSFIFFVLYFSQIKNLKPLKAV
                     FRSIDAYRMDIFTDSLTLSVVTTDIRVLAFVALGAGFVVSLIIPVAALIKLNEKKDNIF
                     GDARFATTNDIRESNSFTLDGDEKDGIIVGIKDKKIIRYVGAAFSAMGAGTRAGKGAGI
                     VITNLMKYWWSVIILDPKRECFNITSLIRKVILGHEVYKFDPFSPVTHRFNPLYYVSMG
                     TSEGFNQLENLALIIYPYKTDGADAGSYLNKTAGGVFKSYAVALWFMIKNDKAGLKTLD
                     IEPVFSMSKINQLFERAEPEHLLSFMNDIRSELRGKDKTLADIGVAGLKAFIEMEDKTK
                     AQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNARLAEKITNIF
                     FQLAIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQV
                     GSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGSKSKSRSRGG
                     TSRSESESLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYLHEYFFGDFVKVA
                     PELANIFPRKKGKLVMPPQKVFENEIVAKGYLAVKEVPDLDKAA"
                     /name="taxB"
     gene            4310..4732
                     /locus_tag="OMD12_RS25410"
                     /old_locus_tag="OMD12_25225"
     CDS             4310..4732
                     /locus_tag="OMD12_RS25410"
                     /old_locus_tag="OMD12_25225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_001328552.1"
                     /translation="MMKKLVFLLISILAGCSSPPEPTPVQFEKANEVINPSLPYVPDFH
                     GVIKSDVSGKGWVYEITSLSGVQARTPTFYYALAHADRIVVTTHDAGLWFRIRDLLKME
                     GATAVVEWRNEKSFLPEQGKIVFIKAQNEVKNDWKK"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            4716..5021
                     /locus_tag="OMD12_RS25415"
                     /old_locus_tag="OMD12_25230"
     CDS             4716..5021
                     /locus_tag="OMD12_RS25415"
                     /old_locus_tag="OMD12_25230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000147044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_000147045.1"
                     /translation="MTGKNRVVLPALLALGLISTNANASDPCASVLCLYGKAVGQGGGS
                     ECRSAEKDFFNILKKKKGSIRWSKTFDARKAFLNQCSTADPAAISKIMSKFGRVKG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            5076..5324
                     /locus_tag="OMD12_RS25420"
                     /old_locus_tag="OMD12_25235"
     CDS             5076..5324
                     /locus_tag="OMD12_RS25420"
                     /old_locus_tag="OMD12_25235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001290044.1"
                     /translation="MSEIRFVTLESDFNNIKEIYSDDELNRLLEAVNQNCPTRIVLGSV
                     EKGKETPLKWCFRTIPERISIEEIDEIKFIQNPSEQG"
                     /name="hypothetical protein"
     gene            5416..5724
                     /locus_tag="OMD12_RS25425"
                     /old_locus_tag="OMD12_25240"
     CDS             5416..5724
                     /locus_tag="OMD12_RS25425"
                     /old_locus_tag="OMD12_25240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000647577.1"
                     /translation="MKARSVRVAGIEIIDSVKTVAYVFTEALLFMVWFSAIVYGLYRVV
                     IVLWDDPLKPQSLMEFLNFIVELYSYVLPSLAVIAVALIAVLSICKILSAIWEGRKQ"
                     /name="hypothetical protein"
     gene            5721..6215
                     /locus_tag="OMD12_RS25430"
                     /old_locus_tag="OMD12_25245"
     CDS             5721..6215
                     /locus_tag="OMD12_RS25430"
                     /old_locus_tag="OMD12_25245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="WP_001215681.1"
                     /translation="MRHFLKALSFVVSLLPATLCAAEIQGKVIRVLDGDTIEVKTLPAK
                     IVVYEVPIRVRLINIDAPEKKQAFGHWSANQLKALLAGQSVTVSYTQTDRYGRIIGRVF
                     TTNGTDASRFMVQSGAAWVYERYNTDKSLPALQREAQEQKRGLWADSNPVPPWEWRHKQ
                     N"
                     /name="thermonuclease family protein"
     gene            6297..7559
                     /locus_tag="OMD12_RS25435"
                     /old_locus_tag="OMD12_25250"
     CDS             6297..7559
                     /locus_tag="OMD12_RS25435"
                     /old_locus_tag="OMD12_25250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517490.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000517489.1"
                     /translation="MGKLTLVEQALRLHKEYYGEDNFGTVVKDCDYYPKVAEIFINRKN
                     RKIYSNLDIEPVASTVVHTGSNPVMAKAGRIKKLMFKDGSGAYRIHLGQNEVVHIIRFI
                     LNSKVRMEYAVGTTKSMSMLHNLCEAGRAKLNRSLPRKGIWKLGYYDGVYYHGKARKEE
                     IENAMRFSVHPKFDELENDFNQFFSDIDFYTRYGQSGMRKVLFTGPPGTGKTTIAKALG
                     AKYQDKYVFVYADDYFKDVCYAAAQKKIPVIIIAEEVDELYRADAGTLSFLDGADTPRN
                     VAGTYVIFSTNYPKRIDPRIRKRPGRIDRIISVGAFRTKAAAACAKMYLPEDVEIDLKE
                     LGAVLDRTTPAEIKEIINIAIGMIRGTKNELSVDVIKNARAFLKGTLDLSVQEADEDIE
                     EREELYKKNGAQPDYLSYLED"
                     /name="AAA family ATPase"
     gene            7563..8135
                     /locus_tag="OMD12_RS25440"
                     /old_locus_tag="OMD12_25255"
     CDS             7563..8135
                     /locus_tag="OMD12_RS25440"
                     /old_locus_tag="OMD12_25255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001199073.1"
                     /translation="MQYALVDALERKFLLDALEFGVLKDWKENPVKELPDIDESVHPFH
                     ICYGGYLLNPGVSDSDISRKIKDQAGFWLAAIDDTRMDCHSIAYYDIHTLPLISCGHQK
                     IVPFAALIKADECIISKIASYSGFAVTAFLRIKEWDIATNILNREGIFAFNGCERRFRV
                     VSKDNWQHTVSEERAIRCAKRLIQCKG"
                     /name="hypothetical protein"
     gene            8140..10293
                     /locus_tag="OMD12_RS25445"
                     /old_locus_tag="OMD12_25260"
     CDS             8140..10293
                     /locus_tag="OMD12_RS25445"
                     /old_locus_tag="OMD12_25260"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_001235747.1"
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPEYKAWKVETLPLRLYPVKYQPVESAAKQVKTILELIRRGDVTEIVHAGD
                     PDDEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKALARS
                     VADAVYGFSMTRAYTIPAKARGYQGVLSVGRVQTPVLGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVIRANWKPGEFAPLTDRKLLDKAWADGTAASLAGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKMTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFPQSLDIDSARKSKAFNSAKVTAHTAIIPTASVPDVNALSTDERNVYLAIAQ
                     HYLVQFMPEKAYQEVSVAIQCGDESFYARARKTTDSGFEAFLGAETTDEGESEDNDDSA
                     FELLCKIRTGETLTTKEVVVNEKKTTPPPLFTEASLLAALVRVADFVTDPTIKKLLKDK
                     DKDKKDEHGGIGTPATRAAILETLKKRNYITLEKGKLIPTDTGYALIDALPGIAVNPDM
                     TALWSEKQTAIENGDLTVEEFINELYGELTGMISDVDLGEMKIEPAAPAGQFQRLDSPC
                     PSCGKHIVIRPKGYFCTGCEFKIWSEFSGKKITQAQAEKLVKSGKTDLIKGFKKKSGGT
                     YDTVLVLEDKKTGKLGFPVRAKK"
                     /name="type IA DNA topoisomerase"
     gene            10290..10496
                     /gene="hha"
                     /locus_tag="OMD12_RS25450"
                     /old_locus_tag="OMD12_25265"
     CDS             10290..10496
                     /gene="hha"
                     /locus_tag="OMD12_RS25450"
                     /old_locus_tag="OMD12_25265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_000850859.1"
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
                     /name="hha"
     gene            10512..10976
                     /locus_tag="OMD12_RS25455"
                     /old_locus_tag="OMD12_25270"
     CDS             10512..10976
                     /locus_tag="OMD12_RS25455"
                     /old_locus_tag="OMD12_25270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293133.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_001293133.1"
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFAREIDFEQLLEMQEKLNVV
                     IEERREDAEREAAERQELEAKRQQAIEYIISLGLDPESLLAPVTADTVKTRRKAKGGVR
                     KAKYRFKDENGEIREWSGNGKRPLALQKLLDEGHFMEDFLIDKLQPGQVE"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            11080..11736
                     /locus_tag="OMD12_RS25460"
                     /old_locus_tag="OMD12_25275"
     CDS             11080..11736
                     /locus_tag="OMD12_RS25460"
                     /old_locus_tag="OMD12_25275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001478769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000972911.1"
                     /translation="MMIKSKKVVVIFVALSSFLLAGCDSPKDANKQNFEKAINTRLEKE
                     CITISPLGMFDSKPYPVQIAVAQANRYTSQERADEINSRQFSALDVLVKADLLTVKNTL
                     VDDVIGFTKTGKKVPGREYALTDEGKKYLKSPERPDFCVGHYKVDEIVDFTEPGDAMGM
                     KITQVNYTFSPTSIAEWAKRDDVRAAFLGLESDLKEKQTKHITLVLKNDGWSAER"
                     /name="hypothetical protein"
     gene            11819..12208
                     /locus_tag="OMD12_RS25465"
                     /old_locus_tag="OMD12_25280"
     CDS             11819..12208
                     /locus_tag="OMD12_RS25465"
                     /old_locus_tag="OMD12_25280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_223196981.1"
                     /translation="MTLSKILTDIFRTANNLTHCKTTNQLLAGDASSTLASAILSCDRY
                     SIFEQDYPRSGLIRQAVRHTGHSVQTSLVTTFKYSVPLSGALFRHMCPYPGLFRITASF
                     SPCPVVHIHLDKNALSEKMSKFFFW"
                     /name="hypothetical protein"
     gene            12293..13117
                     /locus_tag="OMD12_RS25470"
                     /old_locus_tag="OMD12_25285"
     CDS             12293..13117
                     /locus_tag="OMD12_RS25470"
                     /old_locus_tag="OMD12_25285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001487124.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA];
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_016238959.1"
                     /translation="MSDLPASIFQISRSDAWNLTISPDAARNMRDLASQIGAGMPKYLI
                     APEVSLLLSYIDDLNIRMYFETLWNTGARLNEALALKPADFMLTPTRQYPQPVVILKTL
                     KQRLKEAERRPGRPTTRHPPLHPDPRYRKPPEPAVRLVPVLDAGYALRMREYLATWKKR
                     IKHQPVWDITSRQTPLNWINTAVARAERDGVTFSVPVTPHTFRHSYAMHLTMSGVPPRV
                     LQSLLGHRYARSTEIYTRVFSLDVLTGSGLSFTCDPQLAKQLLGYPERLNNE"
                     /name="tyrosine-type recombinase/integrase"
     gene            13222..13881
                     /locus_tag="OMD12_RS25475"
                     /old_locus_tag="OMD12_25290"
     CDS             13222..13881
                     /locus_tag="OMD12_RS25475"
                     /old_locus_tag="OMD12_25290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000516230.1"
                     /translation="MGKIITVAGHKGGIGKSTVLCSLCVCVIKKGKTACFLETDSQGSI
                     KDFIEDRKTNARLSEIPYFECYTDIPAMAQKLAARFDYVFVDTPGMKSPAFVKALSCAH
                     ILFTFIEPGSGIEINTLGRLVFDIKTAQAGVNPSMKAWIVLNKCSTNPSDSEASELRRQ
                     LNDDPDWLPVPRQRIYMRTAHKKAYNNGMGVHEYDDKRGNKARGEIELLLKETDIL"
                     /name="division plane positioning ATPase MipZ"
     gene            14047..14349
                     /locus_tag="OMD12_RS25480"
                     /old_locus_tag="OMD12_25295"
     CDS             14047..14349
                     /locus_tag="OMD12_RS25480"
                     /old_locus_tag="OMD12_25295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001062964.1"
                     /translation="MAKIPKKIDQEIKPLDLRQFVSSAAQKPASASAVTRINLTMTDDD
                     LDTAQVFQNKYGASRAEVIRAALAALRLVSAEERRRLFDDIRKNSPKAGRPTVNK"
                     /name="hypothetical protein"
     gene            14386..14637
                     /locus_tag="OMD12_RS25485"
                     /old_locus_tag="OMD12_25300"
     CDS             14386..14637
                     /locus_tag="OMD12_RS25485"
                     /old_locus_tag="OMD12_25300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001482241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000905709.1"
                     /translation="MLIKIIKSVFNFYMLCVQPFIGLVLAGYGAWKFSGDSISALLEPA
                     SYFVIGTVVLFVWYIAWQKERSKEEEFKSSIKPEDFVK"
                     /name="hypothetical protein"
     gene            complement(15209..15736)
                     /locus_tag="OMD12_RS25490"
                     /old_locus_tag="OMD12_25305"
     CDS             complement(15209..15736)
                     /locus_tag="OMD12_RS25490"
                     /old_locus_tag="OMD12_25305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="WP_000577047.1"
                     /translation="MIFNRNKKRDEQQNSSVVLPSTENVFSDFIKNNPALTTNAFTAIG
                     EVDCFTKVPLLSNKESEFLGILSRNIIPDYSVFPKIRLIEFVRPHGSEEAVKELIREVQ
                     NITCDFVLKSYDETVLAVIQFGETATVRQQKKKLIIQRVCAMTEISFFEFKNTVDMMGS
                     EDFCQFLRDDEE"
                     /name="DUF2726 domain-containing protein"
     gene            complement(15872..16276)
                     /locus_tag="OMD12_RS25495"
                     /old_locus_tag="OMD12_25310"
     CDS             complement(15872..16276)
                     /locus_tag="OMD12_RS25495"
                     /old_locus_tag="OMD12_25310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000654313.1"
                     /translation="MKDNIVDFQRIRRDLGAHSTDVANDAVYSDKKKTSRFFYLLTPVR
                     YLLAASLYLVVVIPLGILAGFRFLLQFLGGIAVMGLTIAWYMGADVSGYIVLAAWIALT
                     VCGCAEQIFEWWIESRFAFRLFGIGRTPEE"
                     /name="hypothetical protein"
     gene            complement(16342..17349)
                     /locus_tag="OMD12_RS25500"
                     /old_locus_tag="OMD12_25315"
     CDS             complement(16342..17349)
                     /locus_tag="OMD12_RS25500"
                     /old_locus_tag="OMD12_25315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243325.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000243326.1"
                     /translation="MVLKNNKNSDCNDVQSLLAQGNQLLEGAYDITLIEMRLLYLALTK
                     IDSRKPQPANEYTLFAKEYRDTFSLDSKNCYEQLKSAASSLGSKPIVTYEWNEAKKRID
                     AVKRFWFSSIRYGVGNSESDITLRFSDSVSQYLYELKSEFTQMNLEHMVKLDTPFSFRL
                     YSWLYKYKNLNRNKKYSGVISTDPITIEWMKERTGLTGKYPVYKDFKKRVLDPAVDIIN
                     ANTNLSVTYEGIKSGRKIESVVFTYLVENETHDGKKIATKPLRPRLPSRPRVIKGSSAE
                     VAWAKKCIDVMKNYLISLREYDDKLKLSRPDLQKVKLWHEITGWDFEESFWFSD"
                     /name="replication initiation protein"
     gene            18893..19228
                     /locus_tag="OMD12_RS25505"
                     /old_locus_tag="OMD12_25320"
     CDS             18893..19228
                     /locus_tag="OMD12_RS25505"
                     /old_locus_tag="OMD12_25320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004026069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001147119.1"
                     /translation="MPYTAKRYQTENGEVPYTDWMKKLRRKDQTAALKVDSRIARAMGG
                     NFGDHKFERDGVWELRVDYGPGYRVYYSIEDGEIILLLIGGNKKTQTADLDKAVSYLQD
                     FKKRSKK"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            19225..19575
                     /locus_tag="OMD12_RS25510"
                     /old_locus_tag="OMD12_25325"
     CDS             19225..19575
                     /locus_tag="OMD12_RS25510"
                     /old_locus_tag="OMD12_25325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000127483.1"
                     /translation="MTATKNVKSQKNDYSASVDHNAAMIEELRADPDYANAYLANALEE
                     INEPGGLGGFLVALRQVIEARGGISEAARKSGLARQSIYRALSPNGNPTITTLAQLTSV
                     AGLQFTLSKSSH"
                     /name="hypothetical protein"
     gene            20214..20729
                     /locus_tag="OMD12_RS25515"
                     /old_locus_tag="OMD12_25330"
     CDS             20214..20729
                     /locus_tag="OMD12_RS25515"
                     /old_locus_tag="OMD12_25330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025396.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025396.1"
                     /translation="MNIQEALNVFGLSGELTEKDIKAAYRKAALKYHPDRNPLGAELMK
                     AVNAAFDVLMANIDKINQFQSTDEHARYNYGDDLEKVLNVLSGLSGLVFEVIGNWVWIS
                     GETITHKETLKEIGCKWAAKKKQWFYRPDEHKSYWNREEHTIEEIRAKYGTTGQRRATG
                     WQRVETRV"
                     /name="J domain-containing protein"
     gene            20834..21376
                     /locus_tag="OMD12_RS25520"
                     /old_locus_tag="OMD12_25335"
     CDS             20834..21376
                     /locus_tag="OMD12_RS25520"
                     /old_locus_tag="OMD12_25335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001083908.1"
                     /translation="MNSFFEQYHPVFEVVCRILGNGWRVNKLDDCSSRIKLTSPQFKNY
                     SVHIRMEKDRFSVVGSVDSRSWRSPHHVCTLSRKRNPVDIAADIERKILVNASQEVLQA
                     IEYEKHQVEKKDEIMILKGMLSQLVQLESWYGALTGFKAENGLNGKVTEQGDSYDLQIR
                     GLSIDQLVKITGYLKQL"
                     /name="hypothetical protein"
     gene            21373..21624
                     /locus_tag="OMD12_RS25525"
                     /old_locus_tag="OMD12_25340"
     CDS             21373..21624
                     /locus_tag="OMD12_RS25525"
                     /old_locus_tag="OMD12_25340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001565860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001230708.1"
                     /translation="MRKNKGDVTYFLEKEGDNYRLTKRIKARTNVKIGNKTTKITLYDA
                     VLNENELQHIDFTCAGLRKDDETPVKNLIKEFMLNETR"
                     /name="hypothetical protein"
     gene            21611..21838
                     /locus_tag="OMD12_RS25530"
                     /old_locus_tag="OMD12_25345"
     CDS             21611..21838
                     /locus_tag="OMD12_RS25530"
                     /old_locus_tag="OMD12_25345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000801440.1"
                     /translation="MKPDNTPENVKKLRLKAGLTQKECSHIYGVGLRTWQKKEEVNTQN
                     SQSLSLVEFEFLLLLAGEHPEYVLCKRESK"
                     /name="hypothetical protein"
     gene            22230..22529
                     /locus_tag="OMD12_RS25535"
                     /old_locus_tag="OMD12_25350"
     CDS             22230..22529
                     /locus_tag="OMD12_RS25535"
                     /old_locus_tag="OMD12_25350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000650313.1"
                     /translation="MKCSSVFTSTTNHVFTFERVTLCTIILMHKDTGQQYVVLFTDNNK
                     IRDYKTGIVPQFGELKQSDVDLVLFYRDEYEKYFDSLKDGDECLSFKDFIECLR"
                     /name="hypothetical protein"
     gene            22621..22986
                     /locus_tag="OMD12_RS25540"
                     /old_locus_tag="OMD12_25355"
     CDS             22621..22986
                     /locus_tag="OMD12_RS25540"
                     /old_locus_tag="OMD12_25355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000854262.1"
                     /translation="MKTLKQAAMQFASDLRNNRCFKAAYNDALLELDREDLNAIVQCTF
                     LFEPKRTLAELDKLIKKIEVEEDYEFCVSLDKGNGLHEVRTFKSEREALDAYRILTLYG
                     YTVTIEKKEGNDWLFKV"
                     /name="hypothetical protein"
     gene            23261..23434
                     /locus_tag="OMD12_RS25545"
                     /old_locus_tag="OMD12_25360"
     CDS             23261..23434
                     /locus_tag="OMD12_RS25545"
                     /old_locus_tag="OMD12_25360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001541980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="WP_071821486.1"
                     /translation="MEDGKEPDTPFKGVFNVRLDPELHRRVAEMAMEEDLSLNAFVNKA
                     LEKEVSNHRAGA"
                     /name="type II toxin-antitoxin system HicB family
                     antitoxin"
     gene            23797..24300
                     /gene="ddp1"
                     /locus_tag="OMD12_RS25550"
                     /old_locus_tag="OMD12_25365"
     CDS             23797..24300
                     /gene="ddp1"
                     /locus_tag="OMD12_RS25550"
                     /old_locus_tag="OMD12_25365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 1"
                     /protein_id="WP_000781818.1"
                     /translation="MKMIAFRLSDDELKLAEHNAISSGFTSINTFARHNVLNVDVQPSN
                     IPVSNESSKAVKTCLYPHEIELVKRNAALHGMSMSREIAIRVRQSLLKNEVCLYPDEVK
                     ELKKLSTAVDRVGRNIHFIIKGERFCTVNDPDFRKDVVEVIELCKQIDSKLETLTKSVV
                     NRFG"
                     /name="ddp1"
     gene            24304..25533
                     /gene="taxC"
                     /locus_tag="OMD12_RS25555"
                     /old_locus_tag="OMD12_25370"
     CDS             24304..25533
                     /gene="taxC"
                     /locus_tag="OMD12_RS25555"
                     /old_locus_tag="OMD12_25370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA relaxase/nickase TaxC"
                     /protein_id="WP_000539545.1"
                     /translation="MGVYVEQEYRIKRAKGTGRDPKSPKLSGRHIHASKSAFNHKVRHG
                     TDKKAYTWTPTKEVTFKITGSGKTAAGIKNGIDYITRNGELEAYCYDGKGSEQTGKGED
                     FNREFTSTLSKGNDYSRTYRGENIDHVKNMVFSPPPEAGVSREDALKATIEFLKETYPN
                     HAFVAVYHDDKEDHPHVHVNIKLRDEETGRRLRLTKSETRKFRNGFHRKLKGMGYDVTA
                     TWKKDPERKREIERLQAENPKRLRNVYKVVDFGETSYQNKAGEKRTPFLTYETLKGGKQ
                     VTIWGKDLKNHFESEKLQPGTLIKVKKLAPTLVRSPMFNDDGTVAGYRETHRNNWQIEN
                     IALERNRERQVHERETRQPEESDVKKQLSRKHEQGHNIGFALEHGFTKDSEEHKKLRIQ
                     QERNWKGLGF"
                     /name="taxC"
     gene            25610..25903
                     /locus_tag="OMD12_RS25560"
                     /old_locus_tag="OMD12_25375"
     CDS             25610..25903
                     /locus_tag="OMD12_RS25560"
                     /old_locus_tag="OMD12_25375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134733.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO:0016987 - sigma factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_000134733.1"
                     /translation="MTEHDAICISALHQIFSDEEHLSEQQKDIILMYAYGYTLNEIADF
                     KGLKPSTVRKYLDSVRAELGGVSLAGIRTLVLIRTNALLVSSLSRISERGNL"
                     /name="sigma factor-like helix-turn-helix DNA-binding
                     protein"
     gene            25900..26115
                     /locus_tag="OMD12_RS25565"
                     /old_locus_tag="OMD12_25380"
     CDS             25900..26115
                     /locus_tag="OMD12_RS25565"
                     /old_locus_tag="OMD12_25380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000760375.1"
                     /translation="MKKYLLFALPFFVVGCSEEVKSVDWWGQHLTEAKQKQAECEKSGS
                     DSQNCKNVKQALFIQSQKDAPVPTFD"
                     /name="EexN family lipoprotein"
     gene            26292..26468
                     /locus_tag="OMD12_RS25570"
                     /old_locus_tag="OMD12_25385"
     CDS             26292..26468
                     /locus_tag="OMD12_RS25570"
                     /old_locus_tag="OMD12_25385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000660496.1"
                     /translation="MKEKPDKSSEKGVYVTIKLDPRLNAFIEEKTKTSLLSKRKQIIYL
                     LMQSMRIDGYMER"
                     /name="hypothetical protein"
     gene            26471..27091
                     /locus_tag="OMD12_RS25575"
                     /old_locus_tag="OMD12_25390"
     CDS             26471..27091
                     /locus_tag="OMD12_RS25575"
                     /old_locus_tag="OMD12_25390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_001299949.1"
                     /translation="MASLFPALLLCAASVHPDTINDIARVESGFNPYAVAEIIPERERG
                     SYGKSVISHMPKSKEEALTVIREIENRKRRYSVGLMQITNSNFSFYSTSAEKLLDPCEN
                     LSVFEKIIVDCYKRGRSLENALSCYYTGNFSNGKRKEKEFNNTSYVERIGYTGNEKKYV
                     VPGTRSNGGEQRKNRSHNASVIWPETILKSAFVDNSHPTKVIN"
                     /name="lytic transglycosylase domain-containing protein"
     gene            27105..27431
                     /locus_tag="OMD12_RS25580"
                     /old_locus_tag="OMD12_25395"
     CDS             27105..27431
                     /locus_tag="OMD12_RS25580"
                     /old_locus_tag="OMD12_25395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000008647.1"
                     /translation="MSFKKSVCNRISSSVTAVMQRKNKVVMAVAGATVASPAFADGFSK
                     AETLLEKVKTGLSGLSLVTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAEVAS
                     MMVN"
                     /name="TrbC/VirB2 family protein"
     gene            27450..30197
                     /locus_tag="OMD12_RS25585"
                     /old_locus_tag="OMD12_25400"
     CDS             27450..30197
                     /locus_tag="OMD12_RS25585"
                     /old_locus_tag="OMD12_25400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="WP_000105985.1"
                     /translation="MSTLYKAMTRPAMYVGVPVVPLTVVAGALFLAGVYISKLIWLAIP
                     VAVFVLRMITKQDDHIFNLYFLKLKMLGNSVCNRFFGARAFLSGQYEAVEIDEFVNAMK
                     LNERITTGKYIPYSSHVDKNIVKTKNGDYVATWQLMGINFESISAEMLETIDSQVATLV
                     RSFSGLPVSFYNHSCRASFYDAFTTKSGNKYADIISDCYYGSMKKNKFKGNTLYFTLIY
                     RPDGRVEKLEKRKKSIKEKKDDINIHVKRMNEMINTFSGALDKFTCKLLGMYEENGKVF
                     SSQLSFYNYLLTGKLQKIRVTDSPVYNVLGGVDVFFNHDTGQICRIDGNKFFRSIEIKD
                     FCSETASGVFDVLQYSDADYIITHSYTSMSKSEALSTIKRAEKQLKSTEDDAVTQLQEL
                     EKAKNDIVSGDISFGYYHFTLMVMADSIRELDESVSKITADFTDLGIIPALSTMSLPAA
                     YFAQLPAVFHLRPRLSPVSNVNFVELASFHNFYQGKRDKNCWTEAVAILKTPSKQAYYL
                     NLHNSVLFKDETGEKNLANTKVIGTAGSGKTMFLSYLACSLQKYNNPETFADSAKNKKL
                     TCVFLDKDRGAELCIRMLGGEYYTVKSGEPTGWNPFALEATKRNRIFVKQLMEILCTRN
                     GERLSTRERLLISESVDAVMDFPPGEMREYGITRMLEHLMQRDDRDEQENGIILRLSQW
                     ANGQAHGWVFDNAKDTFNIQHVNNFGIDGTEFLDDPMVCAPITFYLLYRITQLLDGRRL
                     VIFLDEFWKWLQDEAFSDFVYNKLKTIRKLNGLVIPATQSPDEILKNKISRAVVEVCST
                     SIYLANPDADYNDYVEGLKLTPEEFNIVKNLDPMSRQFLIKKSSLKKGDGKSFSALATL
                     DLSGLGGYLKILSASADNLEIFESIYHEGMEPDDWVPEYLERAI"
                     /name="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
     gene            30209..30925
                     /locus_tag="OMD12_RS25590"
                     /old_locus_tag="OMD12_25405"
     CDS             30209..30925
                     /locus_tag="OMD12_RS25590"
                     /old_locus_tag="OMD12_25405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000832280.1"
                     /translation="MKRVKTFMLISLLTASFYSSAGIPVAIDASPEWAVEAARWTERLK
                     QWSETAQHYQSQIQAYKDQLATATGIRNIAAFTNELSNLQSELTNIYKQGNSYISDFTS
                     NPEGALSSQAKNLFSKYGAFDMCNTGYERNDNLCKARIVSTAASIEQGNEINKQLSNAM
                     SQIQSLSSRIEASKDIKESQDLANALQAQSLKMQAIKMQYDVWNNKNKADHEMLITQEQ
                     EAFIKQQKEAEPLTFD"
                     /name="type IV secretion system protein"
     gene            30937..32031
                     /locus_tag="OMD12_RS25595"
                     /old_locus_tag="OMD12_25410"
     CDS             30937..32031
                     /locus_tag="OMD12_RS25595"
                     /old_locus_tag="OMD12_25410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001677777.1"
                     /GO_process="GO:0030255 - protein secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000046889.1"
                     /translation="MAQGFFVKYNSTVMDSVDKISSSYQTQFANDIMSLATVSVTLYVL
                     WKGYQILASKTQTPLQDLVWDLSKFAIIIMFITNADGYLTAATDALQGMKDGFSGGVSV
                     WQTLDNLWKSTQNLGAEIYSLDKSTYVKDQGVVGQFLIWTGSLILMAVSVVVFLTADVT
                     MKLLIITAPIFIFCLMFGFIRSMFNNWLQSLFSSILTVLFASLVIRIAMDFQGMILSHA
                     IRAAQTGNVNLVSTGAMGFMAGFLGALLVLIAKGFAVQLAGAGVEGAVQGAAMMGLGAA
                     GMATGKSLMLGGRAGLGFGLGMAGRTGMNSLSGKAGNLMGRGARTAAEWAGEKGYQALA
                     PTGALGMKARRLASLEKARARNAA"
                     /name="type IV secretion system protein"
     gene            32546..33232
                     /locus_tag="OMD12_RS25600"
                     /old_locus_tag="OMD12_25415"
     CDS             32546..33232
                     /locus_tag="OMD12_RS25600"
                     /old_locus_tag="OMD12_25415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001290765.1"
                     /translation="MSEKIEKKIETAKSFERQLYAENERSKKNAWRVAVAASLLSLCLG
                     AAICVLVPLKEKELAIVAVGEKTGRTELITQVKQEKILQSEALGRYFVNTYITLREGYN
                     YPSLQYDYETVQLYSSNTVKDDYLRLYNSDMAPDKIYHNNGSYVAVEVISNIISDATAP
                     DKLASVRFKKTTRNFTTGQVSVSYWTARVTYRFEPEKSVKSSSRELNPLGFTVTSYQTD
                     REVRGE"
                     /name="type IV secretion system protein"
     Typing          complement(16343..17349)
                     /name="IncX4"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.702"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          24305..25530
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          4..308
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="99.0"
                     /evalue="7.24e-59"
     Typing          2440..4298
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.839"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          30938..32007
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.72"
                     /coverage="100.0"
                     /evalue="6.640000000000001e-173"
     Typing          32547..33229
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.4399999999999998e-137"
     Typing          33230..33825
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="99.0"
                     /evalue="2.9e-119"
ORIGIN
        1 atgacagtcg tcgtatcgcc cctgattttg cttatgataa tggcatattt acctttttag
       61 gttttaactc agggaaagta ttcccagctc catttgctgt aagagatggt caggaacaga
      121 cacttgcttt taatgtggaa acaaaaggca agtataaaat catggttatc cacaacgtta
      181 atgacaaatt tgttttacgc tatggaaaca gcgttgttgg tgttgtgaat aaatctttcg
      241 gaaaagtatt aaccgaccag aggaatacat cttctcctgc ggtagaacgt gttgaggtga
      301 ataatgactg atatgaaaaa aacagatgat ttagttgatg atgcgaatca gtcaaagctg
      361 gaaagtaaac ccgttcatga tatcggtgat atcaggaaca aaaataatcg tatgcgttct
      421 ggctttctgt ttggtctgat ggctgtatta gttattggta tttttgcgct gaaaacatat
      481 aaaaattatt ttgcagatga ccagcagaaa gcatcagaat caacaggcga taccagcatt
      541 tctcaggtaa gtaaaatccg tactggtctt ggtcagaatt ttgaccctgt tgagaacaaa
      601 gcaattatca atccaggcgc tactggttct ggtaatactg tttctgacgg tcataaagaa
      661 gtgccacagg aggggttcag gaaatatttg tcaatacctg ttgctggtca gggagggagt
      721 cagactggcg cgagtggcag cagcaggaca tcgcagacat cagagccaca ggaagaaagg
      781 aaagaatcaa aagaaaatgt gcctggtaaa tcaggaatga aagtgactgc gattaatctc
      841 gatcctgatc tctatattga ggaaaacagg cttataccgt gtgctttaac cacacgcttt
      901 gtttctgatg ttgcaggtcg tatcagttgt gtttttacag aagatgtatg gagtgctaat
      961 caccacacaa aattactgga acagggaact aaggcttttg gtcgttacca gaccggaacg
     1021 ctgaatcatg gacagggcag aatgttcgtt atgtgggagc agttgcggac gcctgataat
     1081 aaacgaatcg atatggtaaa tacagcagcg gctggtcccc tgggggaagc aggcattgat
     1141 ggatggatcg attctcactt ctgggagcgt tttggtggtt ctcttatgct cagtatggtt
     1201 caggatgtag cggcggcggc ggcggataat gcacctggta aagatcgtaa tgtggattat
     1261 accgaaaact cacgacaggc aatggctgaa atggctaaag ttgcacttga gaattcgata
     1321 aatattcctc caacaatgta taaaaaccaa ggtgacataa tcactattat ggtcggggaa
     1381 gacattgatt tttctgatat ctatgagtta aaggtaaaat agtatgagtg gcgttattcc
     1441 tgtcagcatt agcaataaat cgctcgattt ttataaaaat caagtattcc agtcttttct
     1501 tgatattgaa gggctaacag aaattgctgt caaccgtcct ggtgaaatct ggacggaaat
     1561 taatggtgac tggacattcc ataataatga cggtgtgacc tttgattttt gtaaacgttt
     1621 ttctcagacg ctggcatcat ttcggggaga tgaaatcggc gataccaagc cattactttc
     1681 agcaacactg gaatcaggag aacgtgtaca ggtcgttttt cctcctgcat gtgagagaaa
     1741 tactatttca atcactatac gtaaaccatc gacacggcag ataacgcata aagaatatgt
     1801 ggcgaacggt ttttatgatt atgtccagtc aggaaaaaaa cacaggacat acgatgatga
     1861 gcttcttgat ttattcagag cgagaaatat cgctgctttt atggagcttg ccgtagcagc
     1921 agggaaaacc attgtatttg ccggagcaac gggttccggt aaaacaacct atatgaagag
     1981 tcttatcgat ttcataccat tgaatacgcg gctgattacg attgaagatg cggaggaaat
     2041 caaatttttt attcataaaa attatgtgca tcttttttac ccttcggaat ccggcagtga
     2101 ttccggctct atcataacag cagcgaaatt aatcaaatcc tgtttgagaa tgaaacctga
     2161 cagaatttta ctggcggaaa ttaaaggtgg cgatgcctgg gattttgtga aagttgctgg
     2221 ttctggtcac agtggaagca tgacgtccat tcacgcggcc tcggcaaaag atgccatcat
     2281 tcagatggtg acaaaatgtt atcagaacag agaatgtcaa aatcttcctt ttgatgttct
     2341 tcgtaaaatc attatggaca gtattgatat tgttgttcat gtaggcaggg atggtgttgt
     2401 caggcatatg agcgacatct attacaaagg ggctgaatgt gaaaactttt aataagtcgc
     2461 aatctgtttt tatattcgct gttatgcttg ttgcggcatg gtttgcaggt tcatttattt
     2521 tctttgtgct ttacttcagc cagataaaga atctgaaacc attgaaggct gtgttcagat
     2581 ccattgatgc gtacaggatg gatattttta cagacagcct tactttatct gttgtgacta
     2641 cggatatcag agttttagcc tttgttgcac ttggagcagg atttgtcgtg tctcttatta
     2701 tccctgttgc ggcgttgata aaactgaacg agaagaaaga taatattttt ggtgatgcgc
     2761 gatttgcgac aactaatgat attcgtgagt ctaacagttt cacgcttgac ggtgacgaaa
     2821 aagacgggat tatcgttggt ataaaagaca agaaaatcat acgctatgtg ggagcagcat
     2881 tcagtgcgat gggagccgga acaagggctg gtaaaggtgc aggtatagtc atcactaatc
     2941 ttatgaagta ctggtggagt gttattattc tcgatccaaa aagggagtgt tttaatatca
     3001 ccagtcttat caggaaggtg attttaggtc atgaggttta taaatttgat ccctttagtc
     3061 cggtaacgca ccgctttaac cctttgtatt atgtcagcat gggaacgagt gaaggtttta
     3121 atcagcttga aaatcttgcg ttgattattt acccctataa gacagatggt gcggatgctg
     3181 gtagctatct taataagacg gcggggggtg tttttaaatc ttatgctgtc gctttatggt
     3241 ttatgattaa gaatgataag gctggactaa aaacgcttga tattgagcct gtcttctcaa
     3301 tgtctaaaat taatcagctt tttgagcgtg cagaacccga acatcttctt tcattcatga
     3361 atgatattcg ttcagaatta agggggaaag acaaaacgct tgctgatatt ggtgtcgctg
     3421 gccttaaggc attcattgag atggaggata aaacaaaagc acaactcaaa agcaactttc
     3481 ttaatggatt atcaccgttt gctaacccca atgtggcaaa tgctactgat ggaaatgatt
     3541 ttgatttgcg gcaggtgcgg aaaaagcgga tgacaattta tttctgtatt tctggtgata
     3601 atgccaggtt ggctgaaaaa ataacaaata ttttctttca gcttgctata caggtgaatc
     3661 ttgaaaagat gccaacggat gatccggaaa taaaacatga ctgccttttt ctactggatg
     3721 aattcccgtc aattggtgct gtagattaca tcaagagtaa atctggactc attgctggtt
     3781 acaagctgaa attgttgatt gtttaccagg tcggctctca gcttgaggaa atctacagtt
     3841 atgcaggcag taaaacatta ctggcaagtg caccctgtaa aatcgtttat tccgcttctg
     3901 atgttaaaga tgcgcgggag ttatcagaag cgatgggaac acgaacagta actatcggtt
     3961 cgaaaagcaa aagtcgtagt cgtggaggaa catcgagatc tgaatcagaa agccttattg
     4021 agcgtccact ggtaacaaca aatgaactac ttacactgaa atttagtgaa gaaatcctgg
     4081 caatgaaggg agaaaacccg attcgttgtg aaaaggcatt ctactatctc catgagtatt
     4141 tctttggtga ttttgtgaag gttgctccgg aacttgcaaa cattttcccc aggaagaaag
     4201 gaaagttggt tatgcctcca cagaaagtat ttgaaaatga aatcgtcgca aaagggtatc
     4261 tggcagtaaa agaagttcct gatctcgata aagcggcata aaggagaaca tgatgaagaa
     4321 gttagtgttt ttattgattt ctatccttgc tggttgttca tcaccgccag agccaacacc
     4381 cgtgcagttt gaaaaggcaa atgaagtgat caatccctca ttgccatatg tccccgattt
     4441 tcacggtgtc ataaagtcag acgttagcgg taaaggatgg gtttatgaga tcacttcctt
     4501 atccggagta caggccagaa cgccgacgtt ttattacgct ctggctcatg cggacaggat
     4561 tgtagtgaca acacatgatg ctgggctgtg gtttcgaatc agagatctgt tgaagatgga
     4621 aggggcaaca gcagtcgtgg agtggcgaaa cgagaaaagt tttttacctg aacagggaaa
     4681 aatagttttc attaaagcac aaaacgaggt gaaaaatgac tggaaaaaat agagtggttt
     4741 tacctgcctt gctggcgtta ggattaatat caacaaatgc taatgcatct gatccttgcg
     4801 cttcggtact ttgcttatat ggaaaagcag tcgggcaagg tggagggagt gagtgcagaa
     4861 gtgctgaaaa ggattttttt aatattctga aaaagaaaaa aggaagcatt cgctggagta
     4921 aaacatttga tgcccgtaaa gcatttctga atcagtgttc aacggctgat ccggctgcta
     4981 tctcaaaaat tatgagtaag ttcggacgcg ttaagggctg attaaaacct gatacccgcg
     5041 ccaacgggta tcagtggaca tacaggagaa aaattatgag cgaaatccga tttgtaactc
     5101 tggaatccga ctttaacaat attaaagaaa tttattctga tgatgagtta aaccgtttgc
     5161 tggaagctgt taatcagaat tgcccgacca gaattgtgtt gggtagcgtg gagaagggga
     5221 aagaaacacc actcaagtgg tgttttagaa caataccaga gcgtatttca attgaggaaa
     5281 tcgatgaaat aaaatttatc cagaatcctt ctgaacaggg ataaaggtaa acgccgcaga
     5341 ttccagattt taatctggga tttgcggggt tgaacaaccg aagggcgtta gtttcccgtt
     5401 atccatgagg tatatatgaa agcaagaagt gtgagagttg ccggaattga aattatcgat
     5461 agtgttaaaa cggtcgctta tgtttttact gaggccttac tgtttatggt ctggttttcg
     5521 gcaattgtct atgggcttta tcgtgttgtt atcgttttat gggatgatcc tttaaagccg
     5581 caatcgctca tggaatttct taatttcata gttgagttgt atagctatgt acttccttcg
     5641 ttggctgtta tcgcagtggc tttaatcgcc gttttatcca tttgtaaaat actctcagca
     5701 atatgggagg gaagaaagca atgagacatt ttcttaaggc tctttccttt gttgtttccc
     5761 tgttaccagc tacattgtgt gcggctgaaa tccaggggaa agttattcgc gttctcgatg
     5821 gcgacaccat agaagttaaa acactacccg cgaaaattgt tgtgtatgaa gttccgatca
     5881 gggttcgatt gataaatatc gatgctcctg aaaagaaaca ggctttcggg cactggtcag
     5941 caaatcagct taaagctctg ctcgcaggac aatcagttac cgtctcttat acgcagacag
     6001 accgctacgg acgcattatc ggtcgtgtgt tcacgacgaa cggcacggat gccagccgct
     6061 ttatggttca gtctggcgct gcatgggtat atgaacgtta caacacagat aaatcattac
     6121 cggctttgca acgggaagcg caggaacaaa agcgtggttt atgggctgac agtaatccgg
     6181 ttccaccgtg ggaatggcga cataaacaga actgacgcgc gttgcttgtc caacccctcc
     6241 actaccttaa ataaatttca ggcagtgtca cggttttaaa tatacatggt gcgcttatgg
     6301 gtaaattaac tctggtagag caggctttac ggcttcacaa agaatattac ggtgaagata
     6361 attttggaac tgtcgtaaag gattgtgatt actatcctaa agtggcagag atttttataa
     6421 acagaaagaa ccgtaaaatt tattcgaatc tggatatcga acctgttgct tcaaccgttg
     6481 ttcatacggg aagtaaccct gttatggcta aagctgggag aattaaaaaa cttatgttca
     6541 aagatggttc tggtgcatac aggattcatc ttggtcaaaa tgaagttgtt catattattc
     6601 gcttcattct taactctaaa gtcaggatgg agtacgccgt tgggactact aaaagtatgt
     6661 caatgctcca taatctttgc gaggcaggac gcgctaaatt aaaccgctca ttgccacgta
     6721 aaggtatctg gaaacttggg tactatgatg gtgtttatta tcacggtaag gcaagaaagg
     6781 aggaaattga aaatgctatg cgtttctcag ttcatccaaa atttgacgag ctggaaaacg
     6841 actttaatca gttcttttct gatattgatt tctatacccg gtatggtcag tcaggtatgc
     6901 gtaaagtgct ctttactggc ccccctggaa caggcaagac aactatcgca aaagctttgg
     6961 gggcaaagta tcaggataag tatgtttttg tttatgccga tgattacttt aaagatgttt
     7021 gctacgctgc tgctcagaag aaaatacccg tcattattat agctgaagag gttgatgaac
     7081 tttatcgggc tgatgccgga acgttaagtt ttcttgatgg agctgataca ccgcgaaatg
     7141 tcgcaggtac atatgtgatc ttttctacaa actatccaaa acgcatcgac ccacgtatta
     7201 ggaaacgtcc aggtcgaatt gacaggataa tctctgtagg tgctttcaga accaaagctg
     7261 ctgccgcttg cgccaaaatg tacttaccag aagatgtaga aattgacctt aaagagcttg
     7321 gcgcagtgct ggacagaacg actccggctg aaatcaagga aattattaat atcgcaatcg
     7381 gaatgattcg cggaaccaaa aatgaattat cagtggatgt aataaaaaat gctcgtgcct
     7441 ttttgaaagg aacccttgat ctgagcgtgc aggaagcaga tgaagatata gaggaaaggg
     7501 aagagcttta taaaaagaac ggggcgcaac ctgactattt aagttacctg gaggattaac
     7561 acatgcaata tgcattagtt gatgcgctgg aacgaaaatt tttgctggat gctcttgaat
     7621 ttggtgttct gaaggactgg aaagaaaatc cggtaaaaga acttcctgat attgatgaat
     7681 ctgttcaccc cttccatatc tgttatggtg gatatttatt aaaccctggt gtttcagatt
     7741 cagatattag cagaaaaata aaagaccagg caggattctg gctggcagct attgatgata
     7801 cccgcatgga ttgtcattca atagcttatt atgatattca cacactccct ctgatttcgt
     7861 gtggtcatca aaagatagtt ccttttgccg cgttaataaa agctgatgaa tgcatcattt
     7921 caaaaattgc ttcgtattct ggttttgctg taacagcctt tttgagaatt aaagagtggg
     7981 atattgcaac taatatactt aaccgtgagg gaatttttgc ctttaatggc tgtgagcgca
     8041 gattcagagt agtaagtaaa gataactggc aacatacagt atcggaagaa cgcgctatcc
     8101 gttgtgccaa aagattaatt caatgtaaag gataacaaaa tgagactttt tatcgcagaa
     8161 aaacccgcag tagcaaatga tattgttaag gcacttggtg gcaattttac ccgccatgat
     8221 ggctggtttg aaagtgataa cgccattgtg actaactgtt ttggtcatat tatcgaatca
     8281 cagccgccgg aaaactataa tcctgaatac aaagcctgga aggttgaaac gcttccttta
     8341 cgtctttatc ccgtgaagta tcagcctgtt gaaagtgcag caaaacaggt taaaacgatt
     8401 ctcgagctta tcagacgtgg agacgtgact gaaattgttc acgctggcga tcctgatgat
     8461 gagggacagc tacttgttga tgaagtcctg gaatatgcag gaaacacaaa acccgtaaag
     8521 cgcgttctga ttaacgacaa cacgcttccg gcagtgaaaa aggcactggc aaatcttaaa
     8581 gataatcgtg atttcaaagg gctttacctt aaggcgctgg cgcgttcagt tgctgatgcc
     8641 gtctatggct tctccatgac gcgtgcttac accattccgg caaaagccag aggatatcag
     8701 ggtgttctgt ctgtcgggcg cgtccagact cccgttcttg gcctgattgt gaatcgtacc
     8761 cgtgctaacc agaaccataa atccagtttt tactacacca tgaccggagt ctttcagcgt
     8821 ggtgctgatg ttatcagggc gaactggaag ccaggggaat ttgctccgct gaccgaccgt
     8881 aaattacttg ataaagcgtg ggcagacgga acggcagcat cccttgcagg aaaaccggct
     8941 acagttgaag cggcagcaac tgatgataaa aaaacggctg caccgttgcc gtttaacctg
     9001 gtcagactcc agcaatacat gaacaaaaag ttcaaaatga cggcacaaaa aacactggat
     9061 attacgcaac aattacgtga aaaatataaa gcgattactt ataaccgctc tgattgctca
     9121 tatctttctg atgaacaatt cagcgaagcg ccgcaggtta tcgatgccct gaaatcagtc
     9181 tttcctcagt cgctggatat tgattctgca cgtaaaagca aagcgtttaa cagtgcaaag
     9241 gtgactgcgc atactgcaat aatcccgacc gccagtgtgc ctgatgttaa cgcactcagc
     9301 accgatgagc gcaatgttta cctggcgatc gcacaacact atcttgttca gttcatgcct
     9361 gaaaaagcat accaggaagt atcggttgcc attcagtgtg gtgatgagtc gttctatgcc
     9421 cgtgccagaa aaacaactga cagcggattt gaggcgtttc ttggcgcgga aaccacagac
     9481 gaaggtgaat cagaagataa tgatgattcc gcttttgaac tgctctgtaa aattcgcaca
     9541 ggagaaacac tgacgacaaa agaagttgtc gttaatgaga agaaaacaac accgccgcca
     9601 ttatttaccg aagcctcctt gcttgctgcg cttgttcgcg tcgcggattt tgtcactgac
     9661 ccaacgatta agaaattgct gaaagataag gataaagaca aaaaagatga acatggtggc
     9721 attggtacgc cagctacccg cgcagccatt ctggaaacac tgaagaaaag aaactatatc
     9781 acgctggaaa aagggaaact tattcctact gataccggat atgcgcttat tgatgccctg
     9841 cctggtatag cggttaatcc tgatatgaca gcattatggt ctgaaaagca gacagccatt
     9901 gaaaatggcg acctgacggt tgaagagttt attaatgagc tgtacggtga actgacaggc
     9961 atgatttctg atgttgacct gggcgagatg aagattgaac ccgctgcgcc agcagggcag
    10021 tttcaacgcc tggactctcc ctgcccttcc tgtggtaaac atattgttat cagaccaaaa
    10081 ggttatttct gtaccggatg tgaatttaaa atctggagtg agttttctgg taagaaaatc
    10141 acccaggcgc aggcagaaaa actggttaaa tcagggaaaa ccgatttgat taagggattt
    10201 aaaaagaaaa gcggtggaac gtatgataca gttcttgttc ttgaggataa gaaaacaggg
    10261 aagctgggtt ttccggtaag ggctaagaag tgaaaacaaa gcaggaatgg ctttttcagt
    10321 taagaaaatg tacatcaaga gatactcttg aaaaagttat tgagattaac cgttacaaac
    10381 tgcctttatc agaatcagag gcattttatt ctgccgcaga tcatcgccgc gcagaactgg
    10441 tgatgaataa actgtatgat aaggttcctt ccggcgtctg gaagtacgtc cactaaacaa
    10501 gaggattaat tatgagcgaa ctgactaaag aagatgaata cggcattatc agccggacta
    10561 tgatgaatat tcgttcattg cgtgtttttg cccgtgagat tgattttgag cagttgctcg
    10621 aaatgcagga aaagctcaac gttgttattg aagaacgtcg tgaagatgct gaacgtgaag
    10681 cggctgaacg ccaggaactt gaagccaaac gtcagcaggc cattgaatac atcatatctt
    10741 taggtcttga tcccgaatca ctccttgctc ctgtaacagc tgatacagtg aaaactaggc
    10801 ggaaagccaa aggcggagta agaaaggcta aataccgctt taaggatgaa aatggcgaga
    10861 tcagagaatg gtctggtaat ggcaagcgtc cgcttgcttt acagaagctg cttgatgagg
    10921 gccatttcat ggaagatttc ctcattgaca aactgcaacc tgggcaggtt gaataaaata
    10981 atcgtgatgc cgtcgcaaac aagtttgcga cggcaaatgg aggggacaga acagccagcg
    11041 gcgctggcaa gaaattttat cgtttgataa agagggaaaa tgatgatcaa atcaaaaaaa
    11101 gtagtggtta tttttgttgc tttgagttca ttcttgctgg cagggtgtga ttcaccaaaa
    11161 gatgctaata agcaaaactt tgaaaaagct attaatactc gactagagaa ggaatgcatt
    11221 accattagtc cgctgggaat gtttgatagt aagccttatc cggttcagat agctgtggct
    11281 caggctaatc gatacacatc tcaggaacgg gcagatgaaa taaattctcg acagttttcc
    11341 gcgctggatg tactggtcaa agccgattta ttgacagtaa aaaataccct ggttgatgac
    11401 gttattggtt ttactaagac gggtaaaaaa gtgccaggtc gtgaatatgc tctgacagat
    11461 gaggggaaaa aatatctgaa gtctccggaa cgacctgatt tttgcgtcgg tcattataag
    11521 gtggatgaga tagttgattt taccgaacct ggtgatgcta tgggaatgaa gatcacgcag
    11581 gtgaattaca cattcagtcc caccagtatc gctgaatggg cgaaacgcga tgatgttcgg
    11641 gctgcatttt taggacttga gtctgatttg aaagagaaac aaacaaaaca tattacactg
    11701 gttttgaaaa atgatggatg gtctgctgaa cggtaggctg taatggtgtt gctacgtgaa
    11761 aaatacccca cgtatatccc ctgctttttc acggatttca cgtagcgcac cgccgttaat
    11821 gactctatca aaaatactca ccgatatttt tcgcactgca aacaacctaa ctcactgtaa
    11881 aacaacaaat cagcttctcg ccggtgacgc atcgagcacg ctggccagcg cgatcctcag
    11941 ctgcgaccgc tacagtattt ttgaacaaga ttaccctcgc tccggtttaa ttcgccaggc
    12001 agttagacat acaggtcatt ctgtccagac ttcattagtt acaacattca aatattctgt
    12061 tcctttatcc ggtgccctgt tccggcatat gtgcccatat cctgggttat tcaggataac
    12121 cgcttccttt tcgccctgcc ctgtcgttca tatccacctg gacaaaaatg cattatcgga
    12181 aaaaatgtcc aaattttttt tttggtgatc ggaatttttg ttgtcggacg cacctctgct
    12241 tcaggtcata attgctggca cgtccagaaa aacaggtgcg gagattaaaa aattgagtga
    12301 cttacccgcc agcattttcc agatttcacg tagcgacgcc tggaatttaa ccatctctcc
    12361 cgatgcagcc cgtaatatgc gggatcttgc atcacagatt ggcgcaggaa tgccaaaata
    12421 tctgatagca ccggaagtct cactgcttct ctcctacatc gatgatctga acatacgtat
    12481 gtactttgag acgctctgga ataccggagc acgactgaac gaagctctgg cgctgaaacc
    12541 tgccgatttt atgctgactc cgacgcggca gtacccgcaa cccgtggtga tcctgaaaac
    12601 actcaagcaa cgtctaaaag aagcagaaag aagaccagga cgtccgacca ccagacatcc
    12661 accattacat cctgatccgc gatacagaaa accaccagag cctgctgtaa ggctggttcc
    12721 tgttctggat gccggatacg cattgcgtat gcgggaatac ctggcgacct ggaaaaagcg
    12781 gatcaaacat cagcctgtgt gggacataac atcgagacag acaccgctga actggataaa
    12841 caccgcagtg gcacgggcag agcgtgacgg cgtaacattt tcggttccgg tcactcctca
    12901 cacgttccgc cacagctacg ccatgcacct gacaatgagt ggcgttcctc cgcgcgtcct
    12961 gcaatccctg ctgggacacc gttatgcaag aagcaccgag atttacaccc gcgttttttc
    13021 gctggacgtc cttacaggaa gtggcctgtc ctttacctgc gatccacagc ttgcaaaaca
    13081 gcttcttggg taccctgagc gccttaataa tgagtaataa tacacaccat taaactattg
    13141 ccagcacgca attgtacggt tatactttca ccacaaaaga ttgtgtatta atacacacta
    13201 tttaaccagg aggattttgt gatgggaaaa atcattacag ttgcaggaca caaaggcggc
    13261 ataggaaaaa gcaccgtgct ttgttcctta tgtgtatgtg tcataaagaa agggaaaaca
    13321 gcctgtttcc tggaaacaga ctcacaggga agtatcaagg atttcatcga ggatcgtaaa
    13381 accaacgcca gactgtcaga aataccgtat ttcgaatgct acacggatat tccggctatg
    13441 gcacaaaagc tggccgcccg ctttgattat gtgtttgttg atacaccagg catgaaatct
    13501 ccggcgttcg ttaaagctct gagttgtgct cacattcttt tcacattcat tgagccagga
    13561 tcaggcattg agatcaacac actgggacgg ctggttttcg acattaaaac agcacaggcc
    13621 ggagtcaatc cgtcaatgaa agcatggatt gtcctgaata agtgctcaac taacccgtca
    13681 gacagtgaag cgtcagaact gcgccgacaa ctcaatgatg atccagactg gcttccggtt
    13741 ccccgccagc gtatctatat gcgtactgcg cataaaaaag cctataacaa cggtatgggc
    13801 gtacatgaat acgatgataa acggggaaac aaagcccgtg gcgagattga gttattgtta
    13861 aaagaaacgg atattctgta atgtgtatta ttacacacca aatttgataa tatacccata
    13921 tccgatgcga tatacggcgg ggatggctta tctgaccaag cctggcaatt tgcagtacgt
    13981 ggatgccgga actttccctg ccataaatga tgtgtatagt tacacacctt ataaaaagga
    14041 taccttatgg caaagatccc aaagaaaata gatcaggaaa ttaaaccact ggatttacgc
    14101 cagtttgtaa gttctgctgc acaaaaacca gcatcggcat ccgcagtaac gcgtataaat
    14161 ctgactatga cagatgatga tctggataca gcgcaggtgt tccagaacaa gtacggtgca
    14221 agccgtgctg aagtaatcag agcagcactg gcagcgttac gtctggtatc agcagaagaa
    14281 cgtcggaggc tgtttgatga tataaggaaa aacagcccga aagcaggaag accaaccgtg
    14341 aataaataga gtgttttatt acacactatt aaaggggata aaaatatgct cataaagata
    14401 attaaatctg tattcaattt ttacatgctc tgtgtgcagc cttttattgg actggttctt
    14461 gcgggttatg gtgcatggaa attttcaggt gacagtatct cagcattact ggaaccagca
    14521 tcgtactttg tcattggaac tgttgttttg tttgtatggt atatagcatg gcaaaaagaa
    14581 cgttctaaag aagaagagtt taaatcaagt ataaaaccag aagattttgt gaagtgagga
    14641 tacgtaataa taccagttta taatcagaca ttagggcact caatctatgg aacactgcat
    14701 ctttgattta ggcattataa actatcatcc tgtcattaca tggacagtac cagttgcatt
    14761 tttcttttta gtattgctgg ctggtatagt attcaatatt ggcaggaaaa gtaatctaat
    14821 cgttttcatc ctggcaatgt tgctcccagt aacaacggtt ttcattttta tgttactggg
    14881 cggtaagatc gatatgtgct gaccaattaa aagaggatta aacaatgata aattcaatcg
    14941 cgtttaatct tatagcgtta tgtataatat atatatcatc actatttaaa aaaagtaact
    15001 tcagaatatt ttatataact gtatctacgt gctctttatt attatcatgt gtaccaaaca
    15061 agtacggtat gattggtata gcagcattgg tatttacaac tatgttagga ccattattaa
    15121 ttattttaga ggataacaaa caataaatta tgacaatgcg tttgttaagc ccgcaaatat
    15181 gtgggcttat ttttaatttc taatattttt actcttcatc atctcgcagg aactgacaaa
    15241 agtcttcgct ccccatcata tcgacagtat ttttaaattc gaaaaaagaa atttctgtca
    15301 tagcacacac acgctggata atcagttttt tcttttgctg tctgacggtt gcagtttcac
    15361 caaactggat aacagcaagg actgtttcat catatgattt caggacaaaa tcacaggtta
    15421 tattctgcac ttcacggatt aattctttta cagcttcctc gctaccatga ggacgaacaa
    15481 attcaatgag tcgtattttg ggaaaaacgg aataatcagg tataatatta cgtgaaagaa
    15541 tgcctaaaaa ctctgattcc ttatttgaga gtaagggtac tttagtaaaa caatcaacct
    15601 ccccaatggc tgtaaaagca ttggttgtca aagctggatt gttcttaata aaatcagaga
    15661 atacattttc agttgatggc aaaacaacag aagaattctg ttgttcatct cgttttttat
    15721 tacggttaaa tatcatttca tattcctttt aaaagagcct gcggcaggca caggaaaaaa
    15781 catcgttttt ggacaatcat ggataaaatg ttaacatttt gaccataatt gtctatcctg
    15841 cattgttctt tactgtctgt aagatcagcg ctcattcttc cggcgttctc ccgataccaa
    15901 aaagacggaa cgcaaaacgg ctttcgatcc accattcaaa aatctgctct gcgcaaccac
    15961 aaacagttaa ggcgatccat gcagcaagaa caatgtaacc actgacatct gcacccatgt
    16021 accaggcgat agttaacccc atcactgcga taccgcctaa aaactgcaac aagaaacgaa
    16081 atcccgcaag aatccccaat ggaataacaa caaccagata aagggaagca gccagaaggt
    16141 atctgacagg tgtcagcaga taaaagaacc tggatgtttt ctttttgtca gaataaacgg
    16201 catcatttgc aacatctgtt gaatgagcgc ccaggtctct cctgatacgt tgaaaatcca
    16261 cgatgttatc tttcatatca tcctctcttt taagtgagtt ataaaaagag aaaaaacagg
    16321 taacgtaaac agtagcattc tttaatcact aaaccagaac gactcttcga aatcccatcc
    16381 ggttatttca tgccataact taaccttctg aagatctggc cttgataatt ttaacttatc
    16441 atcatattcc cttaaagaga taagataatt tttcataaca tcgatacatt tttttgccca
    16501 ggctacctcc gcagagcttc ctttaatgac ccttggtctt gatggcaatc gagggcgtaa
    16561 cggtttagtt gctatttttt ttccatcatg tgtttcattc tctacaagat atgtgaacac
    16621 aacagactcg atctttctgc cggacttaat accttcatag gtaacactca gattcgtatt
    16681 tgcattgata atatcaacag caggatcaag cacccgtttc ttaaaatcct tatatactgg
    16741 atatttccct gtaagcccgg ttcgctcctt catccattca atggttatag gatctgtcga
    16801 gatcactcca ctatatttct tatttctgtt cagattctta tatttataca accatgaata
    16861 aagtcgaaat gaaaatggcg tatccagttt caccatatgt tcaagattca tttgtgtaaa
    16921 ttcgcttttc agttcataaa gatattgact aaccgaatct gaaaaacgca aagttatgtc
    16981 actttcacta ttcccaacac catatcttat tgaagaaaac cagaatcgtt tgactgcatc
    17041 gatccttttt tttgcctcgt tccattcata cgtaacaatt ggctttgagc ctaaagaact
    17101 cgcagcagat tttaactgtt cataacaatt tttcgaatct aaagaaaaag tgtccctgta
    17161 ttccttcgca aacaatgtat attcatttgc aggctgtggt ttacggctat caatcttagt
    17221 caatgccaga tacagaagac gcatttcaat tagcgttata tcgtatgcac cttccagcaa
    17281 ttgatttccc tgtgccaaca aactttgaac atcattacag tcgctatttt tattattctt
    17341 taagaccata cagctcccct tcctgtgagt taaaaatcaa aagaagtttc tcacacccaa
    17401 attagggacg caattttttt ttgtccctat atagctaata aaccataaat ctgtcccctg
    17461 tttgaagggt caaacctggc tgaacggcgc attttcaccc tcagtcagag gcagtcaata
    17521 cagcaaacca ggagggaatg catcatcaaa aacccatcga gccaaacatc ctaaatgtga
    17581 tctaagtcac taatccaatt cagattcata gagaatccat aacgaatccg agttgaatct
    17641 aaaaaaagtt atccacaacc tgtggataaa aaagttatcc acactaaatc tgtccctagt
    17701 tgaccataaa tctgtcccct tttaaccata aatctgtccc ctgataaaaa cgcaaataac
    17761 cataaatctg tcccctttta accataaatc tgtccctagt tagcattgca atcaattgaa
    17821 aaacaaaaga aaaaacgacc atgaaaaagg aaatattata tgtaacatag gagtgatcta
    17881 tcttttagaa aaaagaaatt agaaaaaaag aatagagcgc attgtgaatt ttttgagttg
    17941 gaatcagcaa aatcacaaga tgaggtcaga ccagagcgta cggattcata tgctgcatcg
    18001 aagacattcc gcttcctcgc tcactaactc gctccgctcg gtcgttcgac tgcggcgagc
    18061 ggagtcattt ctcacatatc gctggtaatt ctgttgttgt tccttcggtg atgagtcgct
    18121 tgatagccta taaaacacgt tcagaagcgt ctcaggcgca cgaaacgggt ttaaataccc
    18181 cttagggcat gggaggcgcg aaaaacgctt acagaggctt tctgttcatc agaatctgat
    18241 cctgtgaaga ccgagaaagt tctcatgttt agtcacaacc tgaatatttc attccgaggg
    18301 cggtttaata taactagctg attttattga aagagttctt ttaattatga tcctcatttt
    18361 gctaaccgag gatcttctca tgtttcaata aaataccttt aatatcaaca tgatatattc
    18421 ttttgccaat tgatttatgt gaccacttca tttcaacgat acataaatca acagatccag
    18481 caatgcccct ccccaaagtg tcacagagaa gccctgaatc gctctctgcc gcttcgttcg
    18541 atacaaccat gaggaaaacc atgcgaaatg aaaaaaatcg cttaaaacgc gatacagcgc
    18601 gttttagggg gtattcacaa aacacacgtt gccttgaaga aattttgatc aagatttaac
    18661 tactatccgg atcatgacta cagatcacag caacaaggct gctaaaaagc gttgagaggc
    18721 gttaaacgct gttaagacta gggctaagta caatgaaacg gaaaaaatgc tcagaatgcg
    18781 ttacagaacc ttccagaaag ctaggatttc tcactttaaa gagacatttt tcttgatctg
    18841 ttgtcactta taagagacaa tgtacacagg ttaagggaat gagggcggca agatgcctta
    18901 cacggcgaaa cgatatcaga cagaaaacgg tgaggttccg tacaccgact ggatgaaaaa
    18961 attaagacgt aaagaccaga ccgcagcgtt aaaggtggat tccagaattg cccgcgctat
    19021 gggcggaaat tttggagatc ataaattcga aagggacggt gtatgggaat tacgggttga
    19081 ttacggtcct ggttacaggg tttattattc aatcgaagat ggcgaaataa ttcttctgct
    19141 cattggaggg aataaaaaaa ctcagacagc cgatttagat aaagccgtta gttatctgca
    19201 agattttaaa aagaggtcaa aaaaatgaca gcaaccaaaa atgtgaagtc gcagaaaaat
    19261 gattattcgg catccgttga tcacaatgcc gccatgattg aagaattgcg cgcagatcct
    19321 gattatgcaa acgcttatct tgctaatgcc ctggaagaaa taaacgagcc tggtggttta
    19381 ggtggttttc ttgttgcgct acgtcaggta atcgaggcgc gaggggggat ttccgaagct
    19441 gccaggaaat ctggccttgc ccgtcagagt atttaccgcg cattatcccc caacggtaac
    19501 ccgaccatca caacgcttgc acaacttaca tcggtagccg gattacagtt cactctcagt
    19561 aaatccagcc actaatctct ccagttcccc ctaagcgggg gaatttccat gccatcaaaa
    19621 ccgcagttat cccgcccgac gttcaccggt atttaatcgg caaatcgtac aattgcgtac
    19681 tggcaatagt ttaatggtgt gtattaatac acatttaaag gcgatgtgga tgcgtgtgtt
    19741 aatgctaatg tatgcataca ttagcattaa catagagcag attctggcgc gttgcgcccg
    19801 tagttcgctg atgctcacac gcgcagtaca gcgccccgtc ctgttgcgac gcaccaggac
    19861 ggcgtaaact cgcttgcgct cgcgctaact gcggcattct gcggcgcaaa tcagcataat
    19921 catggcctgc tggtcagtta ggctttgcag ggtgaaggga tggccctgtg catcctggta
    19981 cgttcgtcag cggctgcgcc gcgcttcggg gcgatgtggc tcctgtgctg ccctggtatt
    20041 ttcgttcgcc ccttccatcc gcttacgcgg attaaaaaac gtgataacaa tcacttatcg
    20101 agtaaaaaaa acgggagaat acttgcaaat acgacttaat ggtcgtatta ttatttcatc
    20161 gaaaggggaa tggcccctct cacaatagcc cagcagggca ggagatttaa aaaatgaata
    20221 tccaggaagc attaaacgtt tttggattat ccggcgaatt aactgaaaaa gatatcaaag
    20281 cagcatacag aaaagccgcc ttaaaatatc atccagatcg taacccgtta ggggctgaac
    20341 tgatgaaagc ggtaaatgca gcttttgatg tattgatggc aaatattgat aaaataaatc
    20401 agttccagag tactgatgaa catgctcgat ataattacgg tgatgacctg gaaaaagtat
    20461 taaacgttct ttctggttta tctggtctgg tatttgaagt gataggtaac tgggtctgga
    20521 ttagtggaga aactattaca cataaggaaa ctttaaaaga aatcgggtgt aaatgggcgg
    20581 caaagaaaaa acaatggttt tatcgtccag acgaacataa aagttactgg aatcgtgaag
    20641 aacacacgat agaagaaatc cgcgcaaaat acggtacaac cggacagcgc agggcgacag
    20701 ggtggcaacg cgtggaaacc agagtctaac cagaacgggg gcgagaagcc cccgatatta
    20761 tagccagccc gtcttttggg gcatcgaacc caaaaagacg ggaacaggag ccacgtagca
    20821 aaaagggaaa cagatgaact ctttttttga acaatatcac cctgtctttg aagttgtctg
    20881 ccgtatcctg gggaacggct ggcgcgtgaa caaacttgat gattgttcgt ctcgtataaa
    20941 actgacgtca ccgcagttta aaaattactc tgtgcatatt cggatggaaa aagaccggtt
    21001 ttctgttgtg gggagtgtgg atagtcgctc ctggcgtagt ccgcatcatg tttgcacgtt
    21061 atccagaaaa cggaatcccg ttgatattgc agccgatatc gagcgaaaaa ttctggtaaa
    21121 tgcttcgcag gaggtgttac aggcgattga gtatgagaaa caccaggtgg aaaaaaagga
    21181 cgaaattatg atcctgaaag gtatgttatc gcaacttgtc cagcttgaaa gctggtatgg
    21241 ggcattgaca ggctttaaag ctgaaaacgg attgaacggt aaagtcaccg aacagggcga
    21301 cagttatgat ttacagattc ggggcttgag tatagatcaa cttgttaaaa ttacagggta
    21361 tttgaaacag ttatgagaaa aaataaaggt gatgtgactt attttcttga aaaagaaggt
    21421 gacaattaca ggcttacaaa aaggataaaa gccagaacaa atgttaaaat cgggaacaaa
    21481 actacgaaaa tcacattgta tgatgccgta ctgaatgaga atgaattaca acatattgat
    21541 tttacgtgtg ccggattaag gaaagacgat gagacgccag ttaagaattt aattaaggag
    21601 tttatgttaa atgaaacccg ataatacacc tgaaaatgta aaaaaattac gtttaaaagc
    21661 aggattaaca caaaaggaat gcagtcatat ttatggtgtt gggctaagaa cctggcagaa
    21721 aaaagaggaa gttaatactc aaaacagtca aagtctgtca ctggttgagt ttgagtttct
    21781 tttgttactt gcaggagaac atcctgaata cgtgctctgc aaaagggagt caaaataaaa
    21841 tgacctgtga tggttttata ttagtacctg gagttgcgcc cgtagctcgc tgacgctcac
    21901 acgcgcagta cagcgccccg tccaggggaa ccctggacgg cgtaaactcg ctggcgcgag
    21961 cgctaactgc ggcattctgc ggcgcaaatc agcataatca tggcctgctg gtcagttggg
    22021 ctttgcaggg tgaagggatg gcctgtgctg ccctggtatt ttcgttcgcc ccttccatcc
    22081 gcttacgcgg attaaaaacg tgataacaat cacttatcga gtaaaaaaac gggagaacac
    22141 ttgcaaatac gacttgaaag tcgtattatt atttcatcga aaggggaatg gcccctctca
    22201 caatagccca gcagggcagg agatttaaaa tgaaatgctc atctgttttt acttcaacca
    22261 ctaatcatgt tttcacattc gaacgagtaa cgctttgcac tattatcctt atgcataagg
    22321 atacgggaca acagtatgtt gtcctattta ctgataacaa taaaattcgt gactataaaa
    22381 ccggaattgt tcctcagttt ggcgaactta agcagagtga tgttgattta gtccttttct
    22441 acagggacga atatgaaaaa tattttgatt cgttaaaaga tggcgatgaa tgcttgagtt
    22501 ttaaagattt tattgagtgc cttcgttaag cattataaat gcagggggga accctgcatt
    22561 ttctggaaat ttcaatattg attctgaaat tgtctattaa catcaatgca agggaaattc
    22621 atgaaaacgt taaaacaagc cgcaatgcag tttgcatctg atctgcgtaa taatcgctgt
    22681 tttaaagctg cttataatga tgctctgtta gagcttgatc gggaagattt aaatgccatt
    22741 gtacaatgca catttctttt tgagccaaaa cgaacattag ccgaacttga taaattaatt
    22801 aaaaagatag aagtagaaga agattatgag ttttgtgtat cccttgataa aggtaatgga
    22861 ttacacgaag tcagaacatt taaaagtgag cgtgaggcgt tggatgctta tcgcattttg
    22921 accctttacg gatacacagt aactatagaa aagaaggagg gtaatgactg gctattcaag
    22981 gtgtgatcag gttgttccac caacctgatc acgttatcga caatcaaaac tgaatgaggt
    23041 ttttaaatgt caacgcggca gatcgtacag cttgctgatt cccttgtcaa aggctgggaa
    23101 accagaattc cggcaatgaa atttagtgaa tgggatcaat tccggtggtg gttaaactac
    23161 ctgcaagggt atgaaatgtt ttaaataaaa aaaggggctt tctgcccctt tgtatttttt
    23221 gacaaaaatg ctatgtgtag atctgtattt acagtcttgt gtggaggatg gaaaggaacc
    23281 tgataccccg tttaaaggcg tgtttaacgt caggcttgat ccagaactgc atcgtcgggt
    23341 agcagaaatg gcgatggaag aagacttatc gttgaatgcc tttgttaata aggctctgga
    23401 aaaagaagtc agcaatcatc gcgcaggggc ttaattaccc ttgtttttta tgccctgtaa
    23461 gggcatggga ggcgctttgc gccggaagcc ccgcagcgca gcgaggactt aaaaagcgtt
    23521 acggcttcag ccgtaacaat tcccagccct gccaggcctg ttttttcttt cacaaatcta
    23581 tcagctatac gtttgccaga tggtcgaaga cgaaagaacc tttcagcaac gaaatctggg
    23641 catatgcagc gacgatttta tagccaggca cagtgccaca tatggtacaa tcaatgcagg
    23701 atagacaatc atggtcaaaa tgttaacatt ttatccatga ttgtccaaaa acgatgtttt
    23761 tgcctgtgcc tgccgcaggc tctgttgggg tgagttatga agatgatagc gttcagactt
    23821 agtgatgatg agttaaaact tgcagagcat aacgctatat caagtgggtt taccagcatc
    23881 aatacatttg ccaggcataa tgtacttaat gttgatgttc aaccatcaaa tatacccgtc
    23941 agcaatgaat catcaaaggc tgttaaaacc tgtttatacc ctcatgaaat agaacttgtt
    24001 aaacgtaatg cagcccttca cggcatgagc atgagcagag aaattgctat tcgtgtgcgt
    24061 cagtctttgt taaagaatga agtctgtctt taccctgatg aagttaagga acttaaaaaa
    24121 ttatcaactg ctgtagatcg tgttggtcgc aacattcatt ttatcataaa aggtgaaaga
    24181 ttttgcacgg ttaacgatcc tgatttcaga aaagacgttg ttgaagtgat tgaactatgt
    24241 aagcaaattg attcaaaact tgaaacgtta accaagagtg ttgttaacag atttgggtga
    24301 tttatgggtg tgtatgtaga acaggaatac cgtattaaac gcgctaaagg gactgggcgt
    24361 gatccgaaat ctcctaagtt atcgggaaga catatacatg ccagtaaatc ggcttttaat
    24421 cataaagtca gacatggcac agacaagaaa gcatatacct ggacgccaac aaaagaagtc
    24481 acttttaaaa tcacaggttc agggaaaact gccgcaggta tcaaaaacgg tattgattac
    24541 attacccgta atggtgaact tgaggcttac tgttatgatg gaaaaggttc cgagcaaaca
    24601 gggaaaggag aagactttaa cagggagttt acttcaactt tatctaaagg aaatgattac
    24661 tccagaacat atcgtggaga aaacatcgat catgtgaaaa acatggtctt ttcaccacca
    24721 ccagaagctg gagtaagcag ggaagacgct ctgaaagcta cgatagaatt tcttaaagag
    24781 acttatccaa accatgcttt cgttgccgta taccatgatg ataaagaaga tcatcctcat
    24841 gtacatgtta atattaaact tcgtgatgaa gaaacaggaa ggagattaag acttactaag
    24901 tctgaaacca ggaagttcag aaacggtttt catagaaaac tgaaaggtat gggatatgat
    24961 gttaccgcta catggaaaaa agatcccgaa cgtaaacggg agattgagcg attacaggct
    25021 gaaaatccga aaagactccg gaatgtttac aaggttgtgg attttgggga gacttcatat
    25081 cagaataagg caggggaaaa acgaacacct ttcctcactt atgaaacttt aaaaggtgga
    25141 aagcaggtta cgatttgggg taaagacctg aaaaatcatt tcgagtctga aaagctccag
    25201 ccaggaacgc ttatcaaagt taaaaaactg gctcctacgc ttgtacgtag cccgatgttt
    25261 aatgatgatg gaactgttgc aggctacagg gaaacgcatc gcaataactg gcagattgaa
    25321 aatattgccc ttgagcggaa cagagaacgt caggttcatg agcgtgaaac caggcagccg
    25381 gaagagagcg acgttaaaaa gcagctatcc agaaaacatg agcaaggtca caatatcggg
    25441 tttgctcttg aacacgggtt tacaaaggat tcagaagaac ataaaaaact aagaatacag
    25501 caagagagga actggaaagg cctgggattt taatttgatt tcggcgcagg tgaacaaagc
    25561 ggctactttg ctcacctgct aatcacaaca acctacgagg gaggttatca tgactgagca
    25621 tgatgctatc tgcatttctg cacttcatca aatttttagt gatgaagaac atttgagtga
    25681 gcaacaaaaa gacattattc tgatgtacgc ttatggctat accctgaatg aaattgctga
    25741 tttcaaagga ctaaagcctt caactgtcag aaaatatctt gattctgtaa gagctgaact
    25801 gggaggtgtc tcgttggcag ggatcagaac actggtactc attcggacta atgcccttct
    25861 cgtgtcaagt ctttccagga tcagtgagag ggggaattta tgaaaaaata tctgcttttt
    25921 gctttgccgt tcttcgttgt tggttgtagt gaagaagtaa aaagtgtgga ttggtggggg
    25981 cagcatctta cggaagctaa acaaaagcag gcagagtgtg agaagtctgg ctctgattct
    26041 cagaactgta agaatgttaa acaagcattg tttattcagt ctcagaagga tgctccagtc
    26101 cctacattcg attaactaat gtttaaatca tactaaagcg cccatatggg cgcttttttt
    26161 tgcatgatca cacgaatcat aacatgacca ttttgtcaat ggtatttgat cgtattgttg
    26221 agcattgtta ttttgcgaat catgttcgca tctaaaacaa atccaaaaca cacttatagt
    26281 ggattgatta aatgaaggag aaaccagata agtcatcgga aaaaggggtt tatgtcacaa
    26341 taaaactcga tccaaggttg aatgcattta tcgaagagaa aacgaaaaca tctttgctta
    26401 gtaagaggaa gcaaattatt tacttattaa tgcagagtat gcgtattgat ggatatatgg
    26461 agcgttagct atggcgtctt tattcccagc attgttgctg tgtgcggcgt cagttcatcc
    26521 ggatacgata aatgatattg cacgggtcga gagtggcttc aatccttatg ctgtggctga
    26581 aattattcct gaaagggaac gcggtagcta tggcaaaagt gttatcagtc atatgcccaa
    26641 aagtaaggag gaagctctta cagttatcag agaaattgaa aacagaaaaa gacgttattc
    26701 tgtcggattg atgcagatta ccaacagtaa tttttctttt tattccacgt ccgcagaaaa
    26761 actccttgat ccgtgtgaaa acttgtctgt tttcgaaaag attatcgtgg attgttataa
    26821 acgagggagg agcctggaga atgcgcttag ttgttactat acaggaaatt ttagtaacgg
    26881 taagcgaaaa gaaaaagaat ttaataatac aagttatgtt gagcgaattg gttatacagg
    26941 gaacgaaaaa aaatatgttg taccaggtac aagaagcaac gggggagaac agcgaaaaaa
    27001 tcgttcacac aatgcgtcag ttatctggcc cgaaaccatt ctgaaatctg cttttgttga
    27061 taactcacat ccaacaaaag ttattaatta acaggactta taaaatgtca tttaagaaat
    27121 cagtatgtaa tcgtatcagt tcatctgtca ctgctgtaat gcagcgtaaa aataaggtag
    27181 ttatggcagt cgccggggca acagttgcat caccggcctt tgcggatgga ttttcaaaag
    27241 cggaaacgct gctggaaaag gttaaaacag ggcttagtgg tctttcactg gtcacggtga
    27301 ctattgcctg tctgtgggtc ggctacaagg ttctgtttgg tggaagcacg attcgtgaat
    27361 gctcacctat catcatcggg gcaattgtta tcgccagtgc ggctgaagtt gcatcaatga
    27421 tggttaacta ataaagcggg gacgatagta tgtctacact ttataaagcg atgacacgcc
    27481 ctgctatgta tgtgggtgtt cctgtcgtcc ctcttactgt ggttgcaggg gcgttatttc
    27541 tggcgggggt ttatatcagc aagctgatct ggctggctat tcctgtcgcg gtttttgttc
    27601 tcagaatgat aactaaacag gacgaccaca tttttaacct ttactttctt aagctgaaaa
    27661 tgctcggaaa ctcagtgtgt aatcgttttt ttggcgcacg agcgttcctc tccggacaat
    27721 atgaagctgt tgaaattgat gagtttgtta atgccatgaa actgaatgag cgaatcacta
    27781 ctggtaaata tatcccatat tcaagccacg ttgataaaaa catcgtcaaa acaaaaaacg
    27841 gtgattatgt agcgacatgg caactgatgg ggattaactt tgagtcaatc tctgcggaga
    27901 tgttagaaac tattgactca caggttgcca ctcttgttcg ttcattttcc ggactgcccg
    27961 tttcatttta taaccattca tgcagggcga gtttttatga tgcctttacc acaaaatcag
    28021 gtaataaata tgctgatata atatcagatt gttattatgg ttcgatgaag aaaaataaat
    28081 tcaaggggaa cactctttac tttacgctga tctacagacc agacgggcgt gtagaaaaac
    28141 tggaaaaacg caaaaaaagt attaaagaaa agaaagatga tattaacatt catgtgaaga
    28201 gaatgaatga aatgattaat acattctctg gcgctcttga taaatttacc tgtaaacttc
    28261 ttggtatgta tgaggagaac ggaaaggtat tttcttctca actgtcattc tataattatc
    28321 ttctgacagg gaagttgcaa aaaatcagag taactgattc tccggtgtat aacgttcttg
    28381 gtggagtgga tgtgtttttt aaccatgata ccggacagat atgccgcatt gatggaaata
    28441 aattctttcg ttctattgaa attaaagatt tctgtagtga gactgcatcc ggtgtttttg
    28501 atgtgctcca gtattctgat gctgactata ttattacgca ttcatataca tccatgagca
    28561 aatcagaagc attgagtacc attaaacgtg cggaaaaaca gttaaagagt acagaagatg
    28621 atgcggttac tcaattgcag gaactggaaa aggcaaaaaa tgatattgtg tccggtgata
    28681 tatcctttgg ttactaccat ttcacgctaa tggtaatggc ggacagtatc agggagcttg
    28741 acgaatctgt aagtaaaatt acggcagact ttactgacct gggcattatt ccggcattgt
    28801 caaccatgtc attgccagcg gcatattttg cccagcttcc ggcggttttt catttaaggc
    28861 cacgtttatc tccggtatcg aatgtaaatt ttgtcgaact ggcatcattc cataatttct
    28921 accaggggaa acgcgataaa aactgctgga cagaagcggt tgctattctc aaaacaccaa
    28981 gcaaacaggc gtattatctg aatttacata actcagtact gtttaaagat gaaacaggtg
    29041 aaaagaatct tgctaatact aaagttatag gaacggcggg ttcaggtaag acaatgtttc
    29101 tgtcatatct tgcctgttca ttacagaaat acaataaccc cgaaactttt gctgattctg
    29161 caaaaaataa gaagttaacg tgtgtctttc ttgataagga cagaggggct gaattatgta
    29221 tccgaatgct tggtggggaa tattacaccg taaaaagcgg tgagccgaca ggatggaatc
    29281 cttttgctct ggaggcaaca aaacgtaacc gtatttttgt caagcaactg atggagattc
    29341 tgtgtaccag aaatggtgaa agattatcga caagagaaag attgcttatt agcgaaagtg
    29401 ttgatgctgt gatggatttt cctcctggcg aaatgcggga atatggcatt accagaatgc
    29461 ttgagcatct tatgcagaga gatgatcggg atgagcagga gaacgggatt atccttcggt
    29521 tgtcccaatg ggctaatggt caggctcatg gctgggtttt tgataatgct aaagacacat
    29581 tcaatattca gcatgtcaat aattttggca ttgatggcac cgagtttctt gatgatccga
    29641 tggtatgtgc accaattact ttctatctgc tgtatcgcat tacgcagctt cttgacggtc
    29701 ggcgtcttgt tatcttcctg gatgagttct ggaaatggct acaggatgaa gcattcagcg
    29761 actttgtcta taacaagctg aaaacaattc gtaagctgaa cgggctggtt attccggcaa
    29821 ctcagtctcc ggatgaaata ctgaagaata agatttcacg ggctgtggtt gaagtatgca
    29881 gcaccagtat ttatctggct aaccctgatg ccgattacaa tgattatgtg gaagggctta
    29941 agctgacacc agaagaattt aatattgtta aaaatcttga tccaatgtcg agacagttcc
    30001 tgattaaaaa aagcagtctt aaaaaggggg atggtaaatc attttcagca cttgcgacac
    30061 ttgatttatc gggacttggt ggatatctga aaatattgtc tgctagtgca gataatctgg
    30121 aaatttttga aagtatttat catgaaggaa tggagcctga tgactgggtt cctgaatatc
    30181 tcgaacgggc aatctgacag gtgaatttat gaagcgtgta aaaacattta tgctgatatc
    30241 attattgacg gcttcatttt atagtagcgc aggaattccg gttgctattg atgccagtcc
    30301 ggaatgggct gttgaagccg caagatggac agaacgactc aaacaatggt ccgaaactgc
    30361 gcaacattat cagagtcaga ttcaggcata taaagaccag ttagccacgg caacaggtat
    30421 aaggaatatt gcggcattca caaatgaact aagtaatcta caatcagaac tgacaaatat
    30481 ttataagcag gggaacagtt atatttctga ttttaccagt aatcccgaag gtgcattgag
    30541 cagccaggct aaaaatctgt tcagcaagta tggagccttc gatatgtgta atacgggcta
    30601 tgaacgtaat gataatctct gtaaagcacg gattgtgtca acggctgcca gtattgaaca
    30661 gggaaatgag atcaataagc agttatcaaa tgcaatgtct cagattcaga gtttaagtag
    30721 ccgaattgag gcttcaaagg atatcaaaga atcccaggat ttggctaacg cattacaggc
    30781 gcagtcgtta aaaatgcagg cgataaaaat gcagtatgat gtctggaata ataaaaataa
    30841 agcagatcat gagatgttga tcacacaaga acaagaggcc tttattaaac agcagaaaga
    30901 agctgaacca ttaacttttg attaaaaggt ggatatatgg ctcaggggtt tttcgttaaa
    30961 tataattcta ccgttatgga ttcggtagat aaaatcagct ccagttatca aacacaattt
    31021 gctaatgata ttatgtcgtt agcgacggta tcggttacgt tatatgtact atggaaagga
    31081 tatcaaatac ttgccagtaa aactcagacg cccttgcagg atttagtatg ggatctatca
    31141 aaatttgcaa tcataatcat gtttataact aatgcggatg ggtatttaac tgcggccact
    31201 gatgcgttgc aaggcatgaa agatggtttt tctggagggg tgagtgtctg gcaaacttta
    31261 gataacttat ggaaaagtac gcaaaatctt ggcgcggaaa tatactcttt agataaatca
    31321 acatatgtta aagatcaagg tgtagttgga cagtttttaa tatggactgg ctcgcttatt
    31381 ttaatggctg ttagtgtggt tgttttttta acagcagatg taacgatgaa actcctgatt
    31441 attacagcac cgatatttat cttttgtctt atgtttggtt ttattcggag catgtttaat
    31501 aattggttac aatcgttatt ctccagtatt ctgacagttc tatttgccag tttagtgatt
    31561 cggatagcaa tggattttca agggatgatc ctttcccatg ctattcgtgc tgcacaaaca
    31621 ggaaatgtaa atcttgtatc tacaggtgct atgggcttta tggctgggtt tttgggggct
    31681 ttattggttc ttatagctaa aggttttgct gtccagttag caggtgcagg tgttgaaggt
    31741 gctgttcagg gcgcagccat gatggggctg ggtgctgctg gtatggctac tggtaagtct
    31801 ctgatgcttg gcggtcgtgc tggtttaggt tttggcttag ggatggccgg aagaacgggc
    31861 atgaattctt tatctgggaa agcagggaat ctgatggggc gtggtgcgcg aacagccgct
    31921 gaatgggcgg gtgaaaaggg atatcaggcg ctggctccga caggtgcttt ggggatgaag
    31981 gcgagaagac ttgcatccct ggaaaaagca cgagcgagga atgccgcatg aatataatga
    32041 aacgtttttt ttatgtgatg tccctgaact ggatactgac gtttgttgat aaacatatca
    32101 cctccggatg gagcaggaag agaaagctaa taacccagct tattatttta atcacgggaa
    32161 ttaccttatt taaggtctta ggtggaatca gtcagagctg gttgtgacat gcttcattat
    32221 tttgtcatga tactttattt tgtcctaatc cttcttttag gagtgtttac ctgcttcgca
    32281 ggaataagac ttggtttagg gcttgcgggg aaatggagaa agggtatgga tcttcgcttt
    32341 ttgcttctta ttggtgggat tctttttctt catcttggcc tttatctctt aaaggtgttc
    32401 gtgaacgctt aataaggtga atttatgcga tgtgtgattc ttttgttttt cctgtttcag
    32461 atttccggat gtaccacaag gaataccctt ccttctgatg tttccggcga actggaaccc
    32521 attaaccaca gccaggtaat cagttatgag tgaaaaaatc gaaaagaaga ttgagacagc
    32581 taaatccttc gaaagacaac tctatgcaga aaatgaacgg tctaagaaaa atgcatggcg
    32641 tgttgcagtg gcagcatcat tactgtcctt atgtcttggg gctgcaattt gtgttcttgt
    32701 gccattaaaa gaaaaagagc ttgctattgt ggctgttggc gaaaaaacag gccgtacaga
    32761 actgattact caggttaaac aggaaaagat cctgcaatct gaagcgcttg ggcggtattt
    32821 tgtaaacacg tatattactt tacgtgaagg ttataattat ccgtctcttc agtatgatta
    32881 tgagactgta cagctatata gctcgaatac agtaaaggac gattatcttc gtctgtataa
    32941 cagcgatatg gctcctgata aaatttatca taataacggt tcttacgttg cggttgaggt
    33001 catctccaat attatttctg acgcaaccgc gccagataaa ctggcctctg tgcgttttaa
    33061 aaaaacgacg agaaacttca cgaccggaca ggtttcagtt tcatactgga cggctcgtgt
    33121 gacatatcgt tttgaaccag aaaagtcggt taaaagttcc agtcgtgagc ttaatcctct
    33181 cggttttacg gtaaccagtt accagacaga tcgggaagtc aggggggaat gatgaagaaa
    33241 ttatttattg ctacatgttt attgcttcct gggcttgtgt attcagcagc gactccgtta
    33301 ccttctggat ttgatgcaag gatgcagact gtgagttata acggtgcgaa tacgaccgtt
    33361 atccggtcaa agacaggatt tctcacatca gttgtttttg atgaaggtga ggctgttatc
    33421 agtgcaaagg ctggttttcc tgccggatgg gaaatcacaa ccgatgataa tgttgtttac
    33481 atcaatccgc gtcccgttgt tcaggaacag gaaggcgatg aaggcgaaaa actgaaaaag
    33541 gttttccagc caacagaaaa ggaatgggac acgaatcttt ttgtcagaac aacaaagcgg
    33601 atttacagtc ttgatctaat ccttctgtca gaagaaaaac aagcgcaacc tgcttatgtt
    33661 gtacaattcc gctatccatc agaaatagcg aaaaagaatg cagaagaagt aaggctggca
    33721 aaagaaaaac aggaaaaact cagacagaag aaactgattt ctgaaagttt tgaaaaagcc
    33781 gatgcgccta aaaactggga ttatttcatg cgagtcaatg aaaaat
//
