LOCUS       NZ_CP109952            23943 bp    DNA     circular CON 23-NOV-2023
DEFINITION  Klebsiella pneumoniae strain KP1650 plasmid pKP1650-4, complete
            sequence.
ACCESSION   NZ_CP109952
VERSION     NZ_CP109952.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN31373057
            Assembly: GCF_025946845.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 23943)
  AUTHORS   Li,W., Wei,J. and Li,X.
  TITLE     Complete Genome Sequence of Klebsiella pneumoniae KP1650
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 23943)
  AUTHORS   Li,W., Wei,J. and Li,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2022) College of Biological and Environmental
            Engineering, Binzhou University, Huanghe Road, Binzhou 256600, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: HGAP v. 4; FALCON v. 0.3; Canu v. 0.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 30.65x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/23/2023 04:32:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,889
            CDSs (total)                      :: 5,767
            Genes (coding)                    :: 5,582
            CDSs (with protein)               :: 5,582
            Genes (RNA)                       :: 122
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 185
            CDSs (without protein)            :: 185
            Pseudo Genes (ambiguous residues) :: 0 of 185
            Pseudo Genes (frameshifted)       :: 66 of 185
            Pseudo Genes (incomplete)         :: 126 of 185
            Pseudo Genes (internal stop)      :: 23 of 185
            Pseudo Genes (multiple problems)  :: 30 of 185
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP109952.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..23943
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="KP1650"
                     /isolation_source="Bronchoalveolar lavage fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pKP1650-4"
                     /geo_loc_name="China:Zhuhai"
                     /lat_lon="22.28 N 113.58 E"
                     /collection_date="2022-04"
                     /collected_by="Jie Wei"
     gene            407..1894
                     /gene="ltrA"
                     /locus_tag="OIS41_RS29205"
                     /old_locus_tag="OIS41_29210"
     CDS             407..1894
                     /gene="ltrA"
                     /locus_tag="OIS41_RS29205"
                     /old_locus_tag="OIS41_29210"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226014.1"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="WP_004178082.1"
                     /translation="MMYGEEKSDSLIVAAKQANNPKGAESVERRSGAKGNAEQPHMRRT
                     QSRESMSQRLSRVREAAKQRKKERFTALFHLLTVEALEAAFLSLSRKAAAGVDGIRWMD
                     YAGNMKNNITDLHRRLHQGSYRAQPGRRHYIPKADGKQRPLGIASLEDKIVQYALVKIL
                     NAVYENDFMGFSYGFRPGRSQHDALDALATGLVRTNVNWVLDADISQFFDRVSHEWLIR
                     FTEHRIGDRRVIRLIRKWLTAGTSEEGQWRATEEGTPQGAVISPLLANIYLHYVFDLWA
                     HQWRRRYATGNVVMVRYADDIVIGFDKRYDARRFRIAMQRRLREFGLTVHPEKTRLMEF
                     GRFAAENRAIRGKGKPETFNFLGFTHISGKDRNGRFMLIRKTRRDRMTATLKAIKDGLR
                     RRWHYSIPEQGKWLRRVVQGYLNYHSVPGNFPTMQKFRTHVTNLWRRALRRRSQKDDTT
                     WTKANKLAAAWLPRVRVLHPWPVERFTARHPRQEPGA"
                     /name="ltrA"
     gene            1999..3684
                     /locus_tag="OIS41_RS29210"
                     /old_locus_tag="OIS41_29215"
     CDS             1999..3684
                     /locus_tag="OIS41_RS29210"
                     /old_locus_tag="OIS41_29215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_032440457.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IMTSLPADAVTETPASTLPLDQATVRVRQRVVDVVKDERQHIAVVAGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPTAKAPPKGIVAEKGDSRPAGFTAGGNSREAVIR
                     FPKETGQKPVYVSVTDVLTPAQVKQRQEEEKRRQQAWDAAHPEEGLKRDYDKAKAELDA
                     EDKNIATLNSRIASTEKALPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQASLNAMNESLSRDKAALTGAMESRKQKEKKAKDAENKLNE
                     EKNKPRKGTKDYGHDYHPVPKTEDIKGLGELKRGDPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            3694..3951
                     /locus_tag="OIS41_RS29215"
                     /old_locus_tag="OIS41_29220"
     CDS             3694..3951
                     /locus_tag="OIS41_RS29215"
                     /old_locus_tag="OIS41_29220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /GO_function="GO:0015643 - toxic substance binding
                     [Evidence IEA]"
                     /GO_process="GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3-like toxin immunity protein"
                     /protein_id="WP_032440455.1"
                     /translation="MGLKLRLTWFDKKTEEFKGEEYSKDFGDDGSVIESLGMPLKDNIN
                     NGEFDLKKEWVPLLQPFFKNQIKPDVDNCYIAFDYRDGNW"
                     /name="colicin E3-like toxin immunity protein"
     gene            4036..4185
                     /locus_tag="OIS41_RS29220"
                     /old_locus_tag="OIS41_29225"
     CDS             4036..4185
                     /locus_tag="OIS41_RS29220"
                     /old_locus_tag="OIS41_29225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_032440454.1"
                     /translation="MKKVKTIFLFILIVAGFLLAACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            5669..7633
                     /locus_tag="OIS41_RS29225"
                     /old_locus_tag="OIS41_29230"
     CDS             5669..7633
                     /locus_tag="OIS41_RS29225"
                     /old_locus_tag="OIS41_29230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_071177727.1"
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYSLAGFFLVIGLFF
                     GLAELWAGRMRFVGLSHKARREYADRYKRDNNRTVPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLV
                     AGVLLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSTEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSAMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLV
                     AGFNLSETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     KLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFRRWPHASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPADFV
                     KTTVLDNTPIRWFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARLAFSSPLRVERREISLKTFPVLAKTDPLAEY
                     LPPADGGGPKADDDFAGLY"
                     /name="TraM recognition domain-containing protein"
     gene            7633..8364
                     /gene="mobC"
                     /locus_tag="OIS41_RS29230"
                     /old_locus_tag="OIS41_29235"
     CDS             7633..8364
                     /gene="mobC"
                     /locus_tag="OIS41_RS29230"
                     /old_locus_tag="OIS41_29235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_071177728.1"
                     /translation="MTLEQYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQVSVWGLTPHGVAFSFDEDEPLTDVIPFQP
                     SRVSAAQLPHRLAVQSLRLSMEGRGATGWRYLHRMALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRRANGIDEIWYICPDRPTLVRVQRAILAVDEIVNPQTGEA
                     RKTVELDRERLFACFKFMTTE"
                     /name="mobC"
     gene            8371..8901
                     /locus_tag="OIS41_RS29235"
                     /old_locus_tag="OIS41_29240"
     CDS             8371..8901
                     /locus_tag="OIS41_RS29235"
                     /old_locus_tag="OIS41_29240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_071177729.1"
                     /translation="MALYMVFIEDVEDKDGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGENPQWERDKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIEVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(8928..9107)
                     /locus_tag="OIS41_RS29240"
                     /old_locus_tag="OIS41_29245"
     CDS             complement(8928..9107)
                     /locus_tag="OIS41_RS29240"
                     /old_locus_tag="OIS41_29245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165970.1"
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(9133..9561)
                     /locus_tag="OIS41_RS29245"
                     /old_locus_tag="OIS41_29250"
     CDS             complement(9133..9561)
                     /locus_tag="OIS41_RS29245"
                     /old_locus_tag="OIS41_29250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001140599.1"
                     /translation="MAKTLLNLSQAAQAAGITRRTLYNHVKQGKVTVSRDGKNNPVVDV
                     SELIRVYGNVNIPEKQIPGISHRENTQKNFPQEQLLAMQKELADLRQAVTLMLEDKTSR
                     EEERRQHDDERRKLQAEVDRLTTELTQKKKRFWSGWFS"
                     /name="hypothetical protein"
     gene            complement(9725..10039)
                     /locus_tag="OIS41_RS29250"
                     /old_locus_tag="OIS41_29255"
     CDS             complement(9725..10039)
                     /locus_tag="OIS41_RS29250"
                     /old_locus_tag="OIS41_29255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136729.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]; GO:0009432 - SOS response [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_071177730.1"
                     /translation="MPQVTISALAQRDLQRLQDFLKTKNRLAARKGGEVIVRAIQQLKT
                     LPDIGRPVPFLPLEYKELVIGFGDSGYVMLYRHDREMDQIVIVTVRHQKESGYPGADSL
                     "
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(10027..10305)
                     /locus_tag="OIS41_RS29255"
                     /old_locus_tag="OIS41_29260"
     CDS             complement(10027..10305)
                     /locus_tag="OIS41_RS29255"
                     /old_locus_tag="OIS41_29260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014542884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family ribbon-helix-helix protein"
                     /protein_id="WP_000093040.1"
                     /translation="MSSATSIRLDEELKDRLKTLADDRHRSAHALMLEAITEYIDREEK
                     RSQYLRDGQAAWQHYQETGLHLTAEEAEAWISTWGTENEQDAPPCHR"
                     /name="CopG family ribbon-helix-helix protein"
     gene            complement(10480..10845)
                     /locus_tag="OIS41_RS29260"
                     /old_locus_tag="OIS41_29265"
     CDS             complement(10480..10845)
                     /locus_tag="OIS41_RS29260"
                     /old_locus_tag="OIS41_29265"
                     /inference="COORDINATES: protein motif:HMM:TIGR01352.1"
                     /GO_function="GO:0015291 - secondary active transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="WP_072354022.1"
                     /translation="MKAFTLTVLAAMFLTPVHAIPLKPVTTLQPTYPVQAAAKRIEGQV
                     TATFDILDDGRVDNVSLTGCHLFFRETLTAMRHWLYPAGHPAMRQVINFEFSLKNDGLQ
                     DPRPVTTQKLNDDGCRQ"
                     /name="TonB family protein"
     gene            complement(10842..11213)
                     /gene="tolA"
                     /locus_tag="OIS41_RS29265"
                     /old_locus_tag="OIS41_29270"
     CDS             complement(10842..11213)
                     /gene="tolA"
                     /locus_tag="OIS41_RS29265"
                     /old_locus_tag="OIS41_29270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237044.1"
                     /GO_component="GO:0098567 - periplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="WP_001237044.1"
                     /translation="MRLIPFILLALCSPLLLTACKHSTTQPPKIYTLDKSSKISSYAAA
                     IKTAVEMQMFEPEAYAGKMCTVRISIQRDGTLNSAIAEGGDPKLCKAAISAVTHAKIPP
                     APDENTWQIFKNAPLDFRP"
                     /name="tolA"
     gene            complement(11487..11732)
                     /locus_tag="OIS41_RS29270"
                     /old_locus_tag="OIS41_29275"
     CDS             complement(11487..11732)
                     /locus_tag="OIS41_RS29270"
                     /old_locus_tag="OIS41_29275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032440458.1"
                     /translation="MTHLKLTPAEEKRLADAFVAQALAMGLKGNKTLPKAVKQQVRERV
                     LRAIQDEREARRAQEMRREKYEATETTFTWQPQRRR"
                     /name="hypothetical protein"
     gene            12377..13864
                     /gene="ltrA"
                     /locus_tag="OIS41_RS29275"
                     /old_locus_tag="OIS41_29280"
     CDS             12377..13864
                     /gene="ltrA"
                     /locus_tag="OIS41_RS29275"
                     /old_locus_tag="OIS41_29280"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226014.1"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="WP_004178082.1"
                     /translation="MMYGEEKSDSLIVAAKQANNPKGAESVERRSGAKGNAEQPHMRRT
                     QSRESMSQRLSRVREAAKQRKKERFTALFHLLTVEALEAAFLSLSRKAAAGVDGIRWMD
                     YAGNMKNNITDLHRRLHQGSYRAQPGRRHYIPKADGKQRPLGIASLEDKIVQYALVKIL
                     NAVYENDFMGFSYGFRPGRSQHDALDALATGLVRTNVNWVLDADISQFFDRVSHEWLIR
                     FTEHRIGDRRVIRLIRKWLTAGTSEEGQWRATEEGTPQGAVISPLLANIYLHYVFDLWA
                     HQWRRRYATGNVVMVRYADDIVIGFDKRYDARRFRIAMQRRLREFGLTVHPEKTRLMEF
                     GRFAAENRAIRGKGKPETFNFLGFTHISGKDRNGRFMLIRKTRRDRMTATLKAIKDGLR
                     RRWHYSIPEQGKWLRRVVQGYLNYHSVPGNFPTMQKFRTHVTNLWRRALRRRSQKDDTT
                     WTKANKLAAAWLPRVRVLHPWPVERFTARHPRQEPGA"
                     /name="ltrA"
     gene            13969..15654
                     /locus_tag="OIS41_RS29280"
                     /old_locus_tag="OIS41_29285"
     CDS             13969..15654
                     /locus_tag="OIS41_RS29280"
                     /old_locus_tag="OIS41_29285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_032440457.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IMTSLPADAVTETPASTLPLDQATVRVRQRVVDVVKDERQHIAVVAGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPTAKAPPKGIVAEKGDSRPAGFTAGGNSREAVIR
                     FPKETGQKPVYVSVTDVLTPAQVKQRQEEEKRRQQAWDAAHPEEGLKRDYDKAKAELDA
                     EDKNIATLNSRIASTEKALPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQASLNAMNESLSRDKAALTGAMESRKQKEKKAKDAENKLNE
                     EKNKPRKGTKDYGHDYHPVPKTEDIKGLGELKRGDPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            15664..15921
                     /locus_tag="OIS41_RS29285"
                     /old_locus_tag="OIS41_29290"
     CDS             15664..15921
                     /locus_tag="OIS41_RS29285"
                     /old_locus_tag="OIS41_29290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /GO_function="GO:0015643 - toxic substance binding
                     [Evidence IEA]"
                     /GO_process="GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3-like toxin immunity protein"
                     /protein_id="WP_032440455.1"
                     /translation="MGLKLRLTWFDKKTEEFKGEEYSKDFGDDGSVIESLGMPLKDNIN
                     NGEFDLKKEWVPLLQPFFKNQIKPDVDNCYIAFDYRDGNW"
                     /name="colicin E3-like toxin immunity protein"
     gene            16006..16155
                     /locus_tag="OIS41_RS29290"
                     /old_locus_tag="OIS41_29295"
     CDS             16006..16155
                     /locus_tag="OIS41_RS29290"
                     /old_locus_tag="OIS41_29295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_032440454.1"
                     /translation="MKKVKTIFLFILIVAGFLLAACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            17639..19603
                     /locus_tag="OIS41_RS29295"
                     /old_locus_tag="OIS41_29300"
     CDS             17639..19603
                     /locus_tag="OIS41_RS29295"
                     /old_locus_tag="OIS41_29300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_071177727.1"
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYSLAGFFLVIGLFF
                     GLAELWAGRMRFVGLSHKARREYADRYKRDNNRTVPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLV
                     AGVLLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSTEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSAMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLV
                     AGFNLSETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     KLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFRRWPHASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPADFV
                     KTTVLDNTPIRWFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARLAFSSPLRVERREISLKTFPVLAKTDPLAEY
                     LPPADGGGPKADDDFAGLY"
                     /name="TraM recognition domain-containing protein"
     gene            19603..20334
                     /gene="mobC"
                     /locus_tag="OIS41_RS29300"
                     /old_locus_tag="OIS41_29305"
     CDS             19603..20334
                     /gene="mobC"
                     /locus_tag="OIS41_RS29300"
                     /old_locus_tag="OIS41_29305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_071177728.1"
                     /translation="MTLEQYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQVSVWGLTPHGVAFSFDEDEPLTDVIPFQP
                     SRVSAAQLPHRLAVQSLRLSMEGRGATGWRYLHRMALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRRANGIDEIWYICPDRPTLVRVQRAILAVDEIVNPQTGEA
                     RKTVELDRERLFACFKFMTTE"
                     /name="mobC"
     gene            20341..20871
                     /locus_tag="OIS41_RS29305"
                     /old_locus_tag="OIS41_29310"
     CDS             20341..20871
                     /locus_tag="OIS41_RS29305"
                     /old_locus_tag="OIS41_29310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_071177729.1"
                     /translation="MALYMVFIEDVEDKDGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGENPQWERDKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIEVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(20898..21077)
                     /locus_tag="OIS41_RS29310"
                     /old_locus_tag="OIS41_29315"
     CDS             complement(20898..21077)
                     /locus_tag="OIS41_RS29310"
                     /old_locus_tag="OIS41_29315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165970.1"
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(21103..21531)
                     /locus_tag="OIS41_RS29315"
                     /old_locus_tag="OIS41_29320"
     CDS             complement(21103..21531)
                     /locus_tag="OIS41_RS29315"
                     /old_locus_tag="OIS41_29320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001140599.1"
                     /translation="MAKTLLNLSQAAQAAGITRRTLYNHVKQGKVTVSRDGKNNPVVDV
                     SELIRVYGNVNIPEKQIPGISHRENTQKNFPQEQLLAMQKELADLRQAVTLMLEDKTSR
                     EEERRQHDDERRKLQAEVDRLTTELTQKKKRFWSGWFS"
                     /name="hypothetical protein"
     gene            complement(21695..22009)
                     /locus_tag="OIS41_RS29320"
                     /old_locus_tag="OIS41_29325"
     CDS             complement(21695..22009)
                     /locus_tag="OIS41_RS29320"
                     /old_locus_tag="OIS41_29325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136729.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]; GO:0009432 - SOS response [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_071177730.1"
                     /translation="MPQVTISALAQRDLQRLQDFLKTKNRLAARKGGEVIVRAIQQLKT
                     LPDIGRPVPFLPLEYKELVIGFGDSGYVMLYRHDREMDQIVIVTVRHQKESGYPGADSL
                     "
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(21997..22275)
                     /locus_tag="OIS41_RS29325"
                     /old_locus_tag="OIS41_29330"
     CDS             complement(21997..22275)
                     /locus_tag="OIS41_RS29325"
                     /old_locus_tag="OIS41_29330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014542884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family ribbon-helix-helix protein"
                     /protein_id="WP_000093040.1"
                     /translation="MSSATSIRLDEELKDRLKTLADDRHRSAHALMLEAITEYIDREEK
                     RSQYLRDGQAAWQHYQETGLHLTAEEAEAWISTWGTENEQDAPPCHR"
                     /name="CopG family ribbon-helix-helix protein"
     gene            complement(22596..22682)
                     /locus_tag="OIS41_RS29330"
                     /old_locus_tag="OIS41_29335"
     CDS             complement(22596..22682)
                     /locus_tag="OIS41_RS29330"
                     /old_locus_tag="OIS41_29335"
                     /inference="COORDINATES: protein motif:HMM:NF015506.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_264485015.1"
                     /translation="MTATFDILDDGRVDNVSLTGCHLFFRER"
                     /name="hypothetical protein"
     gene            complement(22748..23185)
                     /gene="tolA"
                     /locus_tag="OIS41_RS29335"
                     /old_locus_tag="OIS41_29340"
     CDS             complement(22748..23185)
                     /gene="tolA"
                     /locus_tag="OIS41_RS29335"
                     /old_locus_tag="OIS41_29340"
                     /inference="COORDINATES: protein motif:HMM:TIGR02794.1"
                     /GO_component="GO:0098567 - periplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="WP_264485013.1"
                     /translation="MRLIPFILLALCSPLLLTACKHSTTQPPKIYTLDKSSKISSYAAA
                     IKTAVEMQMFEPEAYAGKMCTVRISIQRDGTLNSAIAEGGDPKLCKAAISAVTHAKIPP
                     APDEKYLANIQKRPSGFQTMKAFTLTVLAAMFLTPVHMRYH"
                     /name="tolA"
     gene            complement(23544..23705)
                     /locus_tag="OIS41_RS29340"
                     /old_locus_tag="OIS41_29345"
     CDS             complement(23544..23705)
                     /locus_tag="OIS41_RS29340"
                     /old_locus_tag="OIS41_29345"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_264485014.1"
                     /translation="MTHLKLTPAEEKRLADAFVAQALAMGLKGNKTLPKAVKTTGAGKG
                     ASCHSGRT"
                     /name="hypothetical protein"
     BGC             1..20654
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(4289..4867)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.282"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(16259..16837)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.282"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          7634..8361
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="93.416"
                     /coverage="100.0"
                     /evalue="1.37e-140"
     Typing          19604..20331
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="93.416"
                     /coverage="100.0"
                     /evalue="1.37e-140"
ORIGIN
        1 cgggaggagt aaggtaataa ttatactgtg tatatgtaca gtgtgcgccg ggagaccggt
       61 tagagatcaa ggggtgaaag tccccgacca ttgaaggacc agcaatccac aaggtccccg
      121 agtcatgcgt tgcataccgc gaggtatggg gcgaagcgtt gacaggggtg ttgacaggcc
      181 agccattgag ccacgaaatg tatattaaat taccgggtgc cgacgttgta ctgttaacgg
      241 aaggcaacat catagggtgc gacactgcga gtgccacatg gacccggcgg ggtctgagac
      301 cctggcatgt caatacgatc tctacgcggg aaccgggaga tctcccctct gaccatctgc
      361 cagtgtcgga gatggcccgc accgggaaga cgaggagtca tagccggtga tgtacggaga
      421 ggagaagtcg gactcgctca tagtagcggc gaagcaggcg aacaacccga aaggagcgga
      481 gtcagtggag cgaaggagcg gggccaaggg gaacgcggaa cagccacaca tgcgccggac
      541 acagagccgg gaaagcatgt cacagaggct gtcacgcgtg cgggaagctg cgaagcagcg
      601 gaagaaagaa cggtttacag cattgttcca cctgctgaca gtcgaagcac tggaagccgc
      661 attcctctcc ctgagcagga aagcggccgc cggagtggat ggcatcaggt ggatggacta
      721 cgccggaaac atgaagaaca acataacaga tctgcaccgg aggctacatc agggcagcta
      781 cagggcgcag cccggcaggc gtcactacat cccaaaagcg gatggaaaac aacgcccgct
      841 cggcatcgcc tcgctggagg acaagatcgt ccagtatgcg ctggtgaaaa tcctgaacgc
      901 agtctatgaa aacgacttta tggggttctc atacgggttc agacccgggc gaagccagca
      961 cgatgcactg gacgcactgg ccacagggct ggtacgcact aacgtaaact gggtactgga
     1021 tgccgacatc agtcagttct tcgacagggt gagccacgaa tggctgatca ggttcacaga
     1081 gcatcggatc ggcgaccgga gggtaatcag gctcatacgt aagtggctca cagccgggac
     1141 gtcggaggag ggtcaatggc gagcaacgga ggaaggcacc ccacagggtg cggtcatctc
     1201 accgctgctg gcaaacatat acctccacta cgtcttcgat ctgtgggcgc atcagtggcg
     1261 acgtcgctat gccacaggca atgtggtaat ggtcagatac gccgatgaca tcgtcatcgg
     1321 gttcgacaaa cgatacgatg cccggcgctt ccgtatagcc atgcagcgca gactgaggga
     1381 gttcggactc acggttcacc cggagaaaac ccgtctgatg gagttcggcc gcttcgctgc
     1441 cgaaaaccgt gccatcaggg gaaaaggcaa accagaaacg ttcaacttcc tcgggttcac
     1501 gcacatcagc gggaaagatc gcaacggcag gttcatgctg atacgaaaga cccgccggga
     1561 tcggatgacg gcaactctga aagccatcaa agacggtctg cgaaggcgct ggcattactc
     1621 aatccccgaa cagggaaaat ggctcaggag agtggttcag ggatacctga actatcactc
     1681 ggtaccgggc aacttcccca ccatgcagaa gttcaggaca cacgtaacaa acctctggcg
     1741 ccgggcgctc aggcgcagga gccagaagga tgatacgacc tggacgaaag caaacaaact
     1801 ggcagccgca tggctaccaa gggttcgggt tcttcatcca tggcctgtgg agcggttcac
     1861 cgccagacac ccgaggcagg agcccggtgc gtaaatcgcg cacgccggga tctgtgcggg
     1921 gggtatccgg taacgggtat ccctaccgcg acatgttggc tttaatttat tgttttaaat
     1981 gtcaaagagg aaaacggtat gagtggtgga gacggtcgag gtccgggtaa ttcaggtctg
     2041 ggacataatg gtggtcaggc cagtgggaat gtgaacggta cgtctggtaa aggtggccct
     2101 tcatcaggtg gtggtacgga tccaaacagc gggccgggct ggggtacgac gcatacgccg
     2161 aatggagata ttcataacta taatccgggg gagtttggta acggcgggag taaacccggt
     2221 ggtaatggtg gtaacagcgg caatcatagc ggtagctctg gtggcggaca gtcttcggcc
     2281 actgcgatgg ccttcggtct gcctgccctg gctactccgg gggctgaagg actggcttta
     2341 tcagtttccg gcgatgcgtt gtcggccgcc gttgctgatg tgctggctgc cctgaagggg
     2401 ccgtttaagt ttggtctgtg ggggattgcg atctacggtg tgctgccttc tgagattgca
     2461 aaagatgatc cgaaaatgat gtcaaaaatt atgacgtcat taccggccga tgcggtgacg
     2521 gagactccgg caagtacttt accactggac caggcgacgg ttcgtgtcag acaacgggtt
     2581 gtggatgtgg tgaaggatga gcggcagcat attgcggttg tcgcaggtcg gccaatgagt
     2641 gtccctgtgg tggatgcgaa accgacaaaa cgtccggggg tattcagtgt gtcgattccg
     2701 ggtctcccgt ctctgcaggt gagcgtaccg aaaggtgttc cgacagcgaa agccccgcca
     2761 aaaggcattg ttgctgaaaa aggtgattca cgtccggctg gttttacagc cggtggtaac
     2821 tcccgtgagg ccgttattcg tttcccgaaa gagaccggac agaagccggt ttatgtgtcg
     2881 gtgacagatg ttcttacccc ggcacaggta aaacagcgtc aggaggaaga aaagcgtcgc
     2941 cagcaggcat gggacgccgc tcatccggaa gaggggctga aaagagacta tgataaagcg
     3001 aaagctgagc tggatgccga agataaaaat attgcgacct taaacagccg cattgcatcg
     3061 acagagaagg cgctccccgg tgcaagggct gctgttcagg aagccgataa aaaggtaaaa
     3121 gaggcagagg caaataaaga tgattttgtg acttataacc cgcctcatga atatggctcc
     3181 gggtggcagg atcaggttcg ctatcttgat aaggatattc agaatcagaa tgagaaatta
     3241 aaagcggctc aggcatcttt aaacgcaatg aatgaatcct tatccagaga taaggctgca
     3301 cttaccgggg cgatggagag ccggaaacaa aaggagaaaa aagcgaagga tgcagaaaat
     3361 aagttaaatg aggaaaagaa caagcctcgc aaggggacta aagactacgg ccatgattat
     3421 catccagtac ctaaaacaga agacataaag ggacttggag agttaaagcg aggtgatcct
     3481 aaaacaccta aacaaggtgg tggtggtaag cgggcccgat ggtatggcga taaaaaacgt
     3541 aaaatttatg aatgggattc ccagcacggt gagcttgaag ggtatcgtgc cagtgatggc
     3601 gaacacctag gcgcatttga tcccaaaacg ggtaagcagg ttaaagggcc agatccaaaa
     3661 cggaacatta aaaaatatct ttgagaggta aatatggggc ttaaattacg tttgacatgg
     3721 tttgataaga aaactgaaga gtttaaaggg gaagagtatt ctaaagactt tggtgacgat
     3781 ggttctgtca ttgaaagctt gggaatgcct ttaaaggata atattaataa tggtgagttt
     3841 gatttgaaga aagaatgggt tcctttacta cagccatttt ttaaaaatca aataaaacct
     3901 gatgtggata attgttatat agcttttgat tatcgggacg gtaactggta acaaaaaatt
     3961 atcaaggatg atttgaaata ctgacttccg gtgttcaggg atgaatgccg gagtctttaa
     4021 atacagggaa agtatatgaa aaaggtaaag actatttttc tttttatatt gattgttgct
     4081 ggctttcttc tggccgcatg tcaggcaaat tatatccggg atgttcaggg cggaacggtg
     4141 gcaccatcgt cctcctctga actgacgggg atcgcggttc agtagaaaag atcaaaggat
     4201 cttcttgaga tccttttttt ctgcgcgtaa tcttttgccc tgtaaacgaa aaaaccacct
     4261 ggggaggtgg tttgatcgaa ggttaagtca gttggggaac tgcttaaccg tggtaactgg
     4321 ctttcgcaga gcacagcaac caaatctgtc cttccagtgt agccggactt tggcgcacac
     4381 ttcaagagca accgcgtgtt tagctaaaca aatcctctgc gaactcccag ttaccaatgg
     4441 ctgctgccag tggcgttttg cgtgctttcc cgggttggac tcaagtgaac agttaccgga
     4501 taaggcgcag cagtcgggct gaacggggag ttcttgctta cagcccagct tggagcgaac
     4561 gacctacacc gagccgagat accagtgtgt gagctatgag aaagcgccac acttcccgca
     4621 agggagaacg gcggacaggt atccggtaaa cggcagggtc ggaacaggag agcgcaagag
     4681 ggagcgacct accggaaacg gtggggatct ttaagtcctg tcgggtttcg cccgtactgt
     4741 cagattcatg gttgagcctc acggctccca cagatgcacc gaaaaagcgt ctgtttatgt
     4801 gaactctggc aggagggcgg agcctatgga aaaacgccac cggcgcggcc ctgccgtttt
     4861 gcctcacatg ttagtcccct gcttatccac ggaatctgtg ggtaactttg tatgtgtccg
     4921 cagcgcccgc cgcagtctca cgcccggagc gtagcgaccg agtgagcgag gaggcgcaat
     4981 ttccccggca cctgcaagac ggtcaccgga cgcgctgatg tgggatattg tcccctgatt
     5041 aagtctttct attccctgac gatcaattat caggataggt gaaccatgtc ggtttttcgc
     5101 tgaacatttt acgttaacct atctctgttg cttttttctc cttgcggaga aatgcaagtc
     5161 atccccgctg gggcgtggct gacttcaggg gaaaagacct tgcttacgct ggctggacgc
     5221 caccgacgca cggtcttttc ccctctttct ggctctgtcc ggctggacgc cggccacgcc
     5281 agaaattcac ccggcccccg tcaggctcac gcctgaccac ccacaaaaat ccacggtgct
     5341 ggacgcacct gacgaagcag caaagctgct cctgattttg cgggtggtca gccgctcgct
     5401 atggcgaact ctgacggggg ccggaacacc ggaaaagacc gcactggggt gccgcctttt
     5461 cctctcacac gctggggcgt gctcgttgtt cctccggggc tgcgcctttt ccgcatgggg
     5521 cggaaagagg ctggcctccg cggtgaaagc tgaacgcaat caccacggac gtgaccgccg
     5581 ccgccatgcc ttggggcatg tccgcggctt gtgcagcggg ggctgcgcat cacgccggta
     5641 aacccgtcgt ctgaaggaga gagattgcat gtttaatacg gattcgcttg cctggcagtg
     5701 gcatatcccg gagctggccc ggcagattta cccgtgggtc agctggctgt accgggagta
     5761 ttacagtctg gccggttttt ttctggttat cggcctgttt ttcggtctgg ctgaactctg
     5821 ggccggccga atgcgttttg tggggctgag ccataaggcg cggcgggagt atgccgatcg
     5881 ctataagcgc gataataacc ggactgtgcc attttcggtg ctggcctcgc tggattcacc
     5941 cgggcggatg gtcagggcac ggcgacatgt ctggaactac gcgtactggc tgaccggcgc
     6001 tgccggtctg gcccttctgg gggggctggt tgtcgccgtg tttatcgaga gctggggaga
     6061 aaccgtcctg cgcccggacc tctatgcgaa cgcagattat tacctgctgc agccggctaa
     6121 cctgttcggg atagcctggt gtgccggagg gcttgtcgcc ggcgtccttc tggcgcggct
     6181 gctggcgttc ctgctgcttg atggtcattt tgcggccgct gacgaggcgg tgaacgcgaa
     6241 actgaatcag gagagccggc gcagcagcca gcggaccgga gaaatgacag acgtccgcca
     6301 cctgcatttc ggggagccgg taccggttaa cgcgctggcc gatttttcca cggagcaggc
     6361 ccggaaacag caggcggtgt ttctgggtaa ggatgagcag ggccagccgg tgctggtccc
     6421 tcgtgatacc tggcgcaaga ccaatattca gatcctcggc ctgcccggga gcggcaagag
     6481 cgcgatggcc accaacgcgc tcattcgctg cgtacgcgat ttcggggacg ctgtggtgta
     6541 cttcgacccc aaaggggacg cgtgggcgcc gcacgtcttc cgggcgcact gcccggactt
     6601 caccctgctg gatctgcggc cggggaaacc ggcgcagctg aatctgttcc gcgatctcga
     6661 ccagtacgcc ctgaagaatc tgctggttgc cgggtttaac ctgagtgaga ccggcgacgt
     6721 ggcggaccac taccgcatca gcgagcagaa agcggcgaag ctgattgcgg agcagttccc
     6781 gcagggggca aacattcagc aggtgctggc ggcggcgtac gcgttgccgg aggccctgaa
     6841 aaaggacgtg aaggggctga tcaccaagct ggagaacgtg gccgacctga gcgtcctgca
     6901 gacggacagc ggtatcgatg tggcggggat aatcaacggc ggcggctgcc tgtacgtcat
     6961 cggctcgatg gacgatgagg cggtgatccg ggtgcagaag atgctgtttg cccgctgcgc
     7021 gcaaatcatc attgcgcggg atgagttccg gaggtggccg cacgcgagca tcatgctcga
     7081 tgagattaaa tatctgctgt cgaagtacgt gctgaacgcg ctggggacgc tgcgcagccg
     7141 ggactgcaac ctgctgctcg cgcaccagtc gctgggcgac ttcggtcagt gcgggcagga
     7201 tctgcccgct gattttgtga aaaccacggt actggataac acgccgatcc gctggttcta
     7261 tcgcgcggcc agccaggagt ccgcgcagtg ggcggcgggc cagaccgggg agatccgggt
     7321 ggacgtggag cgccgccggg ccagccggga ggcggggaac gtggagcaca tcagcggcga
     7381 cagcttcatc cagaaggagg cgcggccgct gtttgacgtg aacaccctgc aacacctgcc
     7441 tgacgggttc gcggtgatga ccgggctggg cgtggcgcgg ctggcgttca gcagcccgct
     7501 gcgggttgag cgccgggaaa tttcgctgaa aaccttcccg gtgctggcga aaacggaccc
     7561 gctggcggag tacctgcctc cggccgacgg cggcggacca aaagcggatg atgattttgc
     7621 ggggctttac tgatgacact ggagcagtac aacgtcagcc acgcgaagcg gcaggcgcgg
     7681 aacgcggaga aaacacggct gaccctgcgc tggctgcggg aagagctgtg ttccacggcg
     7741 gagctggttg cgcgacggct ggggattgcg gcggtacagc cggtttaccg cttcctggac
     7801 agtctggtgg cgaaagggct gctggtccgg gcgaaatacc cggttgacgg ccgtcaggtc
     7861 agcgtgtggg ggctgacgcc gcacggggtg gcgttctcgt tcgacgagga cgagccgctg
     7921 acggacgtta ttccgtttca gccgtcaagg gtgtcggcgg cgcagctgcc gcaccggctg
     7981 gccgtgcagt ccctgcgcct ctccatggag ggccgggggg ccaccggctg gcggtacctg
     8041 caccgtatgg ccctgaaagg gatgaaagtg ccggacgcgc tggcggagct ggacggcaga
     8101 acggtggcat ttgaggtaga gcgcaccgtc aagagccgca ggcggtatca ggaagtggtg
     8161 tccgggtatc tgttcaaccg ccgggcgaac ggcatcgatg aaatctggta catctgccct
     8221 gaccggccga cgcttgtccg ggtacagcgg gcgattctgg cggtggatga aatcgtgaat
     8281 ccacagaccg gcgaggcccg caaaacggtg gagctggacc gggagaggct gttcgcgtgc
     8341 tttaaattta tgacaacgga gtgagggatt atggcgctgt acatggtatt tattgaggac
     8401 gtggaagaca aagacggcga gcgctgcatt atgccaacca gcgagcatct ggaagacatg
     8461 gtggtgctcg cctggcagac cggggcgtat gttttctgtt ttgtcgaccg ggcccagcat
     8521 ctggcgatga tgaaatccat cgggatgtat gacgagcggc tcaacagcga cgaaaaagcc
     8581 acgtactttt tcaccggtga aaatccgcaa tgggaacggg acaaacccac aggaatgaag
     8641 ctgtgtgatt acctctatcg aaaggtggag cggttcgcca tcgagaacgg tgtgcaggtg
     8701 gttgatgccg ggaagtgctc accggagcag attaacgcga tgattgaggt ggtcagcgag
     8761 cggcacgggg aaagcgcggt gaacgagaag ctgaaagcgg agctgatgcg ggaatataac
     8821 agccgctatt ttaacgtgcc ggtgcctgaa ctgccggagg acaaacccgc ccgccggtgg
     8881 tggccgttcg gcaaaaaata acgccagcac cggcatggcc ggtgctgtta ttcttccccg
     8941 agcttatccc gcatcacctg ccagagtgtt tccgcatcct cgtgaagccg ttcgcacatg
     9001 tcggccgggg tatccatgtc cagctcgttc agcttttcca gcaacagcag cgactgatcc
     9061 ttaatgaatt tagccatatt gagggcagtt ttttcctgct tcgtcatgtt ctccattccc
     9121 ttcggtaagt tctcagctaa accagccgga ccagaagcgt tttttcttct gtgtcagttc
     9181 tgttgtcaat ctgtccactt cggcctggag tttccggcgc tcatcatcgt gctggcggcg
     9241 ttcttcttcc cgggatgttt tatcttccag catcagggtg acagcctgcc ggagatcggc
     9301 cagttccttt tgcattgcca gaagctgttc ctgtgggaaa tttttttgtg tattttcacg
     9361 gtgtgaaatg ccgggaattt gtttctcagg gatattcaca tttccgtata cacggatcag
     9421 ttctgacaca tccacgacag ggttgttttt cccgtcacgt gacacggtaa cctttccctg
     9481 ttttacatga ttgtatagcg ttcttctggt aatgcccgcg gcttgtgctg cctgtgaaag
     9541 gttgagcaat gttttcgcca ctgtataccc ctgattttat cgggtgtgaa aggtgtgtaa
     9601 tttctcacgg taaatgtatc gctgaatttt acccgttttt ccgttcagga tgtggttttc
     9661 tgacgcgctg cgcttgtcaa accggcgacg gccacgcaat gaattgcgcc cccgtcatcg
     9721 gttattagag gctgtctgcc cccggatacc cggattcttt ctgatgcctg acggtgacga
     9781 tcacaatctg gtccatttcc cggtcgtggc ggtagagcat cacatagcca ctgtcgccaa
     9841 acccgatcac cagttcctta tattccagcg gcagaaacgg caccgggcgg ccaatgtctg
     9901 gcaatgtttt cagttgctgg atagcccgga cgatcacctc acctcctttt ctggctgcca
     9961 gccgattttt ggttttgaga aagtcctgaa ggcgttgtaa atcgcgctgt gccagcgcgg
    10021 aaatcgttac ctgtggcatg gcggagcatc ctgctcgttc tcagttcccc aggtacttat
    10081 ccaggcttcc gcttcttccg cagtaaggtg cagacccgtt tcctgatagt gctgccatgc
    10141 ggcctgtccg tcccgcaggt actggctgcg cttctcttcc cggtcgatgt attcggtgat
    10201 tgcctccagc attagcgcgt gcgctgagcg gtgccggtca tcggccagcg ttttcagccg
    10261 gtccttaagt tcttcatcga gcctgatgga tgttgctgat gacataaaag cccctttgta
    10321 gtcatatgta ttacacatga ctactttaat ccgtggcggc gctatttgcc agaaatacgg
    10381 cttttgctgc ccatttttca gcttcgcttc cactaatcag ggctgctaca ggctcactca
    10441 tcatccagga ctattgcagc ctgcgggtta aaggacctgt tactggcggc aaccatcatc
    10501 attgagcttt tgggtggtga ctggtcgcgg atcctgtaag ccgtcatttt tcagactgaa
    10561 ttcaaaattt ataacctgtc gcattgccgg gtgccctgcg ggatatagcc agtgcctcat
    10621 tgccgtcagc gtttcccgaa aaaaaaggtg acagccggta agcgacacgt tgtccactcg
    10681 tccatcgtcc agaatatcaa acgtggcggt cacctgacct tcgatgcgtt ttgctgcggc
    10741 ctgtaccggg taggttggct gcagtgtggt tacgggtttt agtggtatcg catgtaccgg
    10801 agtgaggaac atggccgcca gcactgtcag agtaaaagct ttcatggtct gaaatccaga
    10861 ggggcgtttt tgaatatttg ccaggtattt tcatccggtg ccggcggaat tttggcgtgg
    10921 gtaacggctg atattgctgc tttacagagt ttcggatctc ctccttcagc aatggcgctg
    10981 ttcagagtgc catcacgttg tatggatatc cgcacggtgc acatttttcc cgcataggcc
    11041 tctggttcaa acatctgcat ttcaacagcg gtcttgatgg ccgcagcgta gctactgatt
    11101 ttagatgact tatccagagt ataaattttc ggcggctggg tggtggaatg cttacaggcc
    11161 gtcaggagta aggggctgca caatgccagc aggataaagg gtattaaacg catcgggttg
    11221 atgacctgtc agtaaaaaat gttacatgta tatttgtcac tctttacggc cacgttcatt
    11281 tacataaaca cggcttatcg tatcgttttt acaccaaacg gcccgccatg cagttgcgtg
    11341 cataggcatg cagcgggtta caatttaccg ggcgcgtttc cggcggtttt ccgggtggtt
    11401 tgttgcctgt tttatcccgt agccgccgga aacgccctca gaccgtctga gcggtgcggg
    11461 caatgcgacg ttatggtaaa taccccttac cggcggcgct gtggctgcca ggtgaaggtg
    11521 gtttccgtag cctcgtattt ctcccgacgc atttcctgcg cccgcctggc ttcacgttcg
    11581 tcctgaatgg cacgaagcac cctttcccgc acctgttgtt ttaccgcctt tggcagcgtt
    11641 ttgttccctt tcaggcccat ggccagtgcc tgagcgacaa aggcgtccgc caggcgcttt
    11701 tcttcagcgg gagtcagttt caggtgcgtc atagtggcct ccgggcgtct caggtttccc
    11761 gaacagttta accgcaggtc ctctcctcat gccagttagc tttcagatgt gtctatacca
    11821 tctgaaatgt aagtgtgatg aatgtcttaa ataataaaat ttgttgccat gagaaatttt
    11881 cgggaaaaga cgcgatctgc ttacaggtgg ctccgggcgc ttttttgtgc ctgaagatga
    11941 gaactaatct catatattga cacctgaaaa cgggaggagt aaggtaataa ttatactgtg
    12001 tatatgtaca gtgtgcgccg ggagaccggt tagagatcaa ggggtgaaag tccccgacca
    12061 ttgaaggacc agcaatccac aaggtccccg agtcatgcgt tgcataccgc gaggtatggg
    12121 gcgaagcgtt gacaggggtg ttgacaggcc agccattgag ccacgaaatg tatattaaat
    12181 taccgggtgc cgacgttgta ctgttaacgg aaggcaacat catagggtgc gacactgcga
    12241 gtgccacatg gacccggcgg ggtctgagac cctggcatgt caatacgatc tctacgcggg
    12301 aaccgggaga tctcccctct gaccatctgc cagtgtcgga gatggcccgc accgggaaga
    12361 cgaggagtca tagccggtga tgtacggaga ggagaagtcg gactcgctca tagtagcggc
    12421 gaagcaggcg aacaacccga aaggagcgga gtcagtggag cgaaggagcg gggccaaggg
    12481 gaacgcggaa cagccacaca tgcgccggac acagagccgg gaaagcatgt cacagaggct
    12541 gtcacgcgtg cgggaagctg cgaagcagcg gaagaaagaa cggtttacag cattgttcca
    12601 cctgctgaca gtcgaagcac tggaagccgc attcctctcc ctgagcagga aagcggccgc
    12661 cggagtggat ggcatcaggt ggatggacta cgccggaaac atgaagaaca acataacaga
    12721 tctgcaccgg aggctacatc agggcagcta cagggcgcag cccggcaggc gtcactacat
    12781 cccaaaagcg gatggaaaac aacgcccgct cggcatcgcc tcgctggagg acaagatcgt
    12841 ccagtatgcg ctggtgaaaa tcctgaacgc agtctatgaa aacgacttta tggggttctc
    12901 atacgggttc agacccgggc gaagccagca cgatgcactg gacgcactgg ccacagggct
    12961 ggtacgcact aacgtaaact gggtactgga tgccgacatc agtcagttct tcgacagggt
    13021 gagccacgaa tggctgatca ggttcacaga gcatcggatc ggcgaccgga gggtaatcag
    13081 gctcatacgt aagtggctca cagccgggac gtcggaggag ggtcaatggc gagcaacgga
    13141 ggaaggcacc ccacagggtg cggtcatctc accgctgctg gcaaacatat acctccacta
    13201 cgtcttcgat ctgtgggcgc atcagtggcg acgtcgctat gccacaggca atgtggtaat
    13261 ggtcagatac gccgatgaca tcgtcatcgg gttcgacaaa cgatacgatg cccggcgctt
    13321 ccgtatagcc atgcagcgca gactgaggga gttcggactc acggttcacc cggagaaaac
    13381 ccgtctgatg gagttcggcc gcttcgctgc cgaaaaccgt gccatcaggg gaaaaggcaa
    13441 accagaaacg ttcaacttcc tcgggttcac gcacatcagc gggaaagatc gcaacggcag
    13501 gttcatgctg atacgaaaga cccgccggga tcggatgacg gcaactctga aagccatcaa
    13561 agacggtctg cgaaggcgct ggcattactc aatccccgaa cagggaaaat ggctcaggag
    13621 agtggttcag ggatacctga actatcactc ggtaccgggc aacttcccca ccatgcagaa
    13681 gttcaggaca cacgtaacaa acctctggcg ccgggcgctc aggcgcagga gccagaagga
    13741 tgatacgacc tggacgaaag caaacaaact ggcagccgca tggctaccaa gggttcgggt
    13801 tcttcatcca tggcctgtgg agcggttcac cgccagacac ccgaggcagg agcccggtgc
    13861 gtaaatcgcg cacgccggga tctgtgcggg gggtatccgg taacgggtat ccctaccgcg
    13921 acatgttggc tttaatttat tgttttaaat gtcaaagagg aaaacggtat gagtggtgga
    13981 gacggtcgag gtccgggtaa ttcaggtctg ggacataatg gtggtcaggc cagtgggaat
    14041 gtgaacggta cgtctggtaa aggtggccct tcatcaggtg gtggtacgga tccaaacagc
    14101 gggccgggct ggggtacgac gcatacgccg aatggagata ttcataacta taatccgggg
    14161 gagtttggta acggcgggag taaacccggt ggtaatggtg gtaacagcgg caatcatagc
    14221 ggtagctctg gtggcggaca gtcttcggcc actgcgatgg ccttcggtct gcctgccctg
    14281 gctactccgg gggctgaagg actggcttta tcagtttccg gcgatgcgtt gtcggccgcc
    14341 gttgctgatg tgctggctgc cctgaagggg ccgtttaagt ttggtctgtg ggggattgcg
    14401 atctacggtg tgctgccttc tgagattgca aaagatgatc cgaaaatgat gtcaaaaatt
    14461 atgacgtcat taccggccga tgcggtgacg gagactccgg caagtacttt accactggac
    14521 caggcgacgg ttcgtgtcag acaacgggtt gtggatgtgg tgaaggatga gcggcagcat
    14581 attgcggttg tcgcaggtcg gccaatgagt gtccctgtgg tggatgcgaa accgacaaaa
    14641 cgtccggggg tattcagtgt gtcgattccg ggtctcccgt ctctgcaggt gagcgtaccg
    14701 aaaggtgttc cgacagcgaa agccccgcca aaaggcattg ttgctgaaaa aggtgattca
    14761 cgtccggctg gttttacagc cggtggtaac tcccgtgagg ccgttattcg tttcccgaaa
    14821 gagaccggac agaagccggt ttatgtgtcg gtgacagatg ttcttacccc ggcacaggta
    14881 aaacagcgtc aggaggaaga aaagcgtcgc cagcaggcat gggacgccgc tcatccggaa
    14941 gaggggctga aaagagacta tgataaagcg aaagctgagc tggatgccga agataaaaat
    15001 attgcgacct taaacagccg cattgcatcg acagagaagg cgctccccgg tgcaagggct
    15061 gctgttcagg aagccgataa aaaggtaaaa gaggcagagg caaataaaga tgattttgtg
    15121 acttataacc cgcctcatga atatggctcc gggtggcagg atcaggttcg ctatcttgat
    15181 aaggatattc agaatcagaa tgagaaatta aaagcggctc aggcatcttt aaacgcaatg
    15241 aatgaatcct tatccagaga taaggctgca cttaccgggg cgatggagag ccggaaacaa
    15301 aaggagaaaa aagcgaagga tgcagaaaat aagttaaatg aggaaaagaa caagcctcgc
    15361 aaggggacta aagactacgg ccatgattat catccagtac ctaaaacaga agacataaag
    15421 ggacttggag agttaaagcg aggtgatcct aaaacaccta aacaaggtgg tggtggtaag
    15481 cgggcccgat ggtatggcga taaaaaacgt aaaatttatg aatgggattc ccagcacggt
    15541 gagcttgaag ggtatcgtgc cagtgatggc gaacacctag gcgcatttga tcccaaaacg
    15601 ggtaagcagg ttaaagggcc agatccaaaa cggaacatta aaaaatatct ttgagaggta
    15661 aatatggggc ttaaattacg tttgacatgg tttgataaga aaactgaaga gtttaaaggg
    15721 gaagagtatt ctaaagactt tggtgacgat ggttctgtca ttgaaagctt gggaatgcct
    15781 ttaaaggata atattaataa tggtgagttt gatttgaaga aagaatgggt tcctttacta
    15841 cagccatttt ttaaaaatca aataaaacct gatgtggata attgttatat agcttttgat
    15901 tatcgggacg gtaactggta acaaaaaatt atcaaggatg atttgaaata ctgacttccg
    15961 gtgttcaggg atgaatgccg gagtctttaa atacagggaa agtatatgaa aaaggtaaag
    16021 actatttttc tttttatatt gattgttgct ggctttcttc tggccgcatg tcaggcaaat
    16081 tatatccggg atgttcaggg cggaacggtg gcaccatcgt cctcctctga actgacgggg
    16141 atcgcggttc agtagaaaag atcaaaggat cttcttgaga tccttttttt ctgcgcgtaa
    16201 tcttttgccc tgtaaacgaa aaaaccacct ggggaggtgg tttgatcgaa ggttaagtca
    16261 gttggggaac tgcttaaccg tggtaactgg ctttcgcaga gcacagcaac caaatctgtc
    16321 cttccagtgt agccggactt tggcgcacac ttcaagagca accgcgtgtt tagctaaaca
    16381 aatcctctgc gaactcccag ttaccaatgg ctgctgccag tggcgttttg cgtgctttcc
    16441 cgggttggac tcaagtgaac agttaccgga taaggcgcag cagtcgggct gaacggggag
    16501 ttcttgctta cagcccagct tggagcgaac gacctacacc gagccgagat accagtgtgt
    16561 gagctatgag aaagcgccac acttcccgca agggagaacg gcggacaggt atccggtaaa
    16621 cggcagggtc ggaacaggag agcgcaagag ggagcgacct accggaaacg gtggggatct
    16681 ttaagtcctg tcgggtttcg cccgtactgt cagattcatg gttgagcctc acggctccca
    16741 cagatgcacc gaaaaagcgt ctgtttatgt gaactctggc aggagggcgg agcctatgga
    16801 aaaacgccac cggcgcggcc ctgccgtttt gcctcacatg ttagtcccct gcttatccac
    16861 ggaatctgtg ggtaactttg tatgtgtccg cagcgcccgc cgcagtctca cgcccggagc
    16921 gtagcgaccg agtgagcgag gaggcgcaat ttccccggca cctgcaagac ggtcaccgga
    16981 cgcgctgatg tgggatattg tcccctgatt aagtctttct attccctgac gatcaattat
    17041 caggataggt gaaccatgtc ggtttttcgc tgaacatttt acgttaacct atctctgttg
    17101 cttttttctc cttgcggaga aatgcaagtc atccccgctg gggcgtggct gacttcaggg
    17161 gaaaagacct tgcttacgct ggctggacgc caccgacgca cggtcttttc ccctctttct
    17221 ggctctgtcc ggctggacgc cggccacgcc agaaattcac ccggcccccg tcaggctcac
    17281 gcctgaccac ccacaaaaat ccacggtgct ggacgcacct gacgaagcag caaagctgct
    17341 cctgattttg cgggtggtca gccgctcgct atggcgaact ctgacggggg ccggaacacc
    17401 ggaaaagacc gcactggggt gccgcctttt cctctcacac gctggggcgt gctcgttgtt
    17461 cctccggggc tgcgcctttt ccgcatgggg cggaaagagg ctggcctccg cggtgaaagc
    17521 tgaacgcaat caccacggac gtgaccgccg ccgccatgcc ttggggcatg tccgcggctt
    17581 gtgcagcggg ggctgcgcat cacgccggta aacccgtcgt ctgaaggaga gagattgcat
    17641 gtttaatacg gattcgcttg cctggcagtg gcatatcccg gagctggccc ggcagattta
    17701 cccgtgggtc agctggctgt accgggagta ttacagtctg gccggttttt ttctggttat
    17761 cggcctgttt ttcggtctgg ctgaactctg ggccggccga atgcgttttg tggggctgag
    17821 ccataaggcg cggcgggagt atgccgatcg ctataagcgc gataataacc ggactgtgcc
    17881 attttcggtg ctggcctcgc tggattcacc cgggcggatg gtcagggcac ggcgacatgt
    17941 ctggaactac gcgtactggc tgaccggcgc tgccggtctg gcccttctgg gggggctggt
    18001 tgtcgccgtg tttatcgaga gctggggaga aaccgtcctg cgcccggacc tctatgcgaa
    18061 cgcagattat tacctgctgc agccggctaa cctgttcggg atagcctggt gtgccggagg
    18121 gcttgtcgcc ggcgtccttc tggcgcggct gctggcgttc ctgctgcttg atggtcattt
    18181 tgcggccgct gacgaggcgg tgaacgcgaa actgaatcag gagagccggc gcagcagcca
    18241 gcggaccgga gaaatgacag acgtccgcca cctgcatttc ggggagccgg taccggttaa
    18301 cgcgctggcc gatttttcca cggagcaggc ccggaaacag caggcggtgt ttctgggtaa
    18361 ggatgagcag ggccagccgg tgctggtccc tcgtgatacc tggcgcaaga ccaatattca
    18421 gatcctcggc ctgcccggga gcggcaagag cgcgatggcc accaacgcgc tcattcgctg
    18481 cgtacgcgat ttcggggacg ctgtggtgta cttcgacccc aaaggggacg cgtgggcgcc
    18541 gcacgtcttc cgggcgcact gcccggactt caccctgctg gatctgcggc cggggaaacc
    18601 ggcgcagctg aatctgttcc gcgatctcga ccagtacgcc ctgaagaatc tgctggttgc
    18661 cgggtttaac ctgagtgaga ccggcgacgt ggcggaccac taccgcatca gcgagcagaa
    18721 agcggcgaag ctgattgcgg agcagttccc gcagggggca aacattcagc aggtgctggc
    18781 ggcggcgtac gcgttgccgg aggccctgaa aaaggacgtg aaggggctga tcaccaagct
    18841 ggagaacgtg gccgacctga gcgtcctgca gacggacagc ggtatcgatg tggcggggat
    18901 aatcaacggc ggcggctgcc tgtacgtcat cggctcgatg gacgatgagg cggtgatccg
    18961 ggtgcagaag atgctgtttg cccgctgcgc gcaaatcatc attgcgcggg atgagttccg
    19021 gaggtggccg cacgcgagca tcatgctcga tgagattaaa tatctgctgt cgaagtacgt
    19081 gctgaacgcg ctggggacgc tgcgcagccg ggactgcaac ctgctgctcg cgcaccagtc
    19141 gctgggcgac ttcggtcagt gcgggcagga tctgcccgct gattttgtga aaaccacggt
    19201 actggataac acgccgatcc gctggttcta tcgcgcggcc agccaggagt ccgcgcagtg
    19261 ggcggcgggc cagaccgggg agatccgggt ggacgtggag cgccgccggg ccagccggga
    19321 ggcggggaac gtggagcaca tcagcggcga cagcttcatc cagaaggagg cgcggccgct
    19381 gtttgacgtg aacaccctgc aacacctgcc tgacgggttc gcggtgatga ccgggctggg
    19441 cgtggcgcgg ctggcgttca gcagcccgct gcgggttgag cgccgggaaa tttcgctgaa
    19501 aaccttcccg gtgctggcga aaacggaccc gctggcggag tacctgcctc cggccgacgg
    19561 cggcggacca aaagcggatg atgattttgc ggggctttac tgatgacact ggagcagtac
    19621 aacgtcagcc acgcgaagcg gcaggcgcgg aacgcggaga aaacacggct gaccctgcgc
    19681 tggctgcggg aagagctgtg ttccacggcg gagctggttg cgcgacggct ggggattgcg
    19741 gcggtacagc cggtttaccg cttcctggac agtctggtgg cgaaagggct gctggtccgg
    19801 gcgaaatacc cggttgacgg ccgtcaggtc agcgtgtggg ggctgacgcc gcacggggtg
    19861 gcgttctcgt tcgacgagga cgagccgctg acggacgtta ttccgtttca gccgtcaagg
    19921 gtgtcggcgg cgcagctgcc gcaccggctg gccgtgcagt ccctgcgcct ctccatggag
    19981 ggccgggggg ccaccggctg gcggtacctg caccgtatgg ccctgaaagg gatgaaagtg
    20041 ccggacgcgc tggcggagct ggacggcaga acggtggcat ttgaggtaga gcgcaccgtc
    20101 aagagccgca ggcggtatca ggaagtggtg tccgggtatc tgttcaaccg ccgggcgaac
    20161 ggcatcgatg aaatctggta catctgccct gaccggccga cgcttgtccg ggtacagcgg
    20221 gcgattctgg cggtggatga aatcgtgaat ccacagaccg gcgaggcccg caaaacggtg
    20281 gagctggacc gggagaggct gttcgcgtgc tttaaattta tgacaacgga gtgagggatt
    20341 atggcgctgt acatggtatt tattgaggac gtggaagaca aagacggcga gcgctgcatt
    20401 atgccaacca gcgagcatct ggaagacatg gtggtgctcg cctggcagac cggggcgtat
    20461 gttttctgtt ttgtcgaccg ggcccagcat ctggcgatga tgaaatccat cgggatgtat
    20521 gacgagcggc tcaacagcga cgaaaaagcc acgtactttt tcaccggtga aaatccgcaa
    20581 tgggaacggg acaaacccac aggaatgaag ctgtgtgatt acctctatcg aaaggtggag
    20641 cggttcgcca tcgagaacgg tgtgcaggtg gttgatgccg ggaagtgctc accggagcag
    20701 attaacgcga tgattgaggt ggtcagcgag cggcacgggg aaagcgcggt gaacgagaag
    20761 ctgaaagcgg agctgatgcg ggaatataac agccgctatt ttaacgtgcc ggtgcctgaa
    20821 ctgccggagg acaaacccgc ccgccggtgg tggccgttcg gcaaaaaata acgccagcac
    20881 cggcatggcc ggtgctgtta ttcttccccg agcttatccc gcatcacctg ccagagtgtt
    20941 tccgcatcct cgtgaagccg ttcgcacatg tcggccgggg tatccatgtc cagctcgttc
    21001 agcttttcca gcaacagcag cgactgatcc ttaatgaatt tagccatatt gagggcagtt
    21061 ttttcctgct tcgtcatgtt ctccattccc ttcggtaagt tctcagctaa accagccgga
    21121 ccagaagcgt tttttcttct gtgtcagttc tgttgtcaat ctgtccactt cggcctggag
    21181 tttccggcgc tcatcatcgt gctggcggcg ttcttcttcc cgggatgttt tatcttccag
    21241 catcagggtg acagcctgcc ggagatcggc cagttccttt tgcattgcca gaagctgttc
    21301 ctgtgggaaa tttttttgtg tattttcacg gtgtgaaatg ccgggaattt gtttctcagg
    21361 gatattcaca tttccgtata cacggatcag ttctgacaca tccacgacag ggttgttttt
    21421 cccgtcacgt gacacggtaa cctttccctg ttttacatga ttgtatagcg ttcttctggt
    21481 aatgcccgcg gcttgtgctg cctgtgaaag gttgagcaat gttttcgcca ctgtataccc
    21541 ctgattttat cgggtgtgaa aggtgtgtaa tttctcacgg taaatgtatc gctgaatttt
    21601 acccgttttt ccgttcagga tgtggttttc tgacgcgctg cgcttgtcaa accggcgacg
    21661 gccacgcaat gaattgcgcc cccgtcatcg gttattagag gctgtctgcc cccggatacc
    21721 cggattcttt ctgatgcctg acggtgacga tcacaatctg gtccatttcc cggtcgtggc
    21781 ggtagagcat cacatagcca ctgtcgccaa acccgatcac cagttcctta tattccagcg
    21841 gcagaaacgg caccgggcgg ccaatgtctg gcaatgtttt cagttgctgg atagcccgga
    21901 cgatcacctc acctcctttt ctggctgcca gccgattttt ggttttgaga aagtcctgaa
    21961 ggcgttgtaa atcgcgctgt gccagcgcgg aaatcgttac ctgtggcatg gcggagcatc
    22021 ctgctcgttc tcagttcccc aggtacttat ccaggcttcc gcttcttccg cagtaaggtg
    22081 cagacccgtt tcctgatagt gctgccatgc ggcctgtccg tcccgcaggt actggctgcg
    22141 cttctcttcc cggtcgatgt attcggtgat tgcctccagc attagcgcgt gcgctgagcg
    22201 gtgccggtca tcggccagcg ttttcagccg gtccttaagt tcttcatcga gcctgatgga
    22261 tgttgctgat gacataaaag cccctttgta gtcatatgta ttacacatga ctactttaat
    22321 ccgtggcggc gctatttgcc agaaatacgg cttttgctgc ccatttttca gcttcgcttc
    22381 cactaatcag ggctgctaca ggctcactca tcatccagga ctattgcagc ctgcgggtta
    22441 aaggacctgt tactggcggc aaccatcatc attgagcttt tgggtggtga ctggtcgcgg
    22501 atcctgtaag ccgtcatttt tcagactgaa ttcaaaattt ataacctgtc gcattgccgg
    22561 gtgccctgcg ggatatagcc agtgcctcat tgccgtcagc gttcccgaaa aaaaaggtga
    22621 cagccggtaa gcgacacgtt gtccactcgt ccatcgtcca gaatatcaaa cgtggcggtc
    22681 acctgacctt cgatgcgttt tgctgcggcc tgtaccgggt aggttggctg cagtgtggtt
    22741 acgggtttta gtggtatcgc atgtgtaccg gagtgaggaa catggccgcc agcactgtca
    22801 gagtaaaagc tttcatggtc tgaaatccag aggggcgttt ttgaatattt gccaggtatt
    22861 tttcatccgg tgccggcgga attttggcgt gggtaacggc tgatattgct gctttacaga
    22921 gtttcggatc tcctccttca gcaatggcgc tgttcagagt gccatcacgt tgtatggata
    22981 tccgcacggt gcacattttt cccgcatagg cctctggttc aaacatctgc atttcaacag
    23041 cggtcttgat ggccgcagcg tagctactga ttttagatga cttatccaga gtataaattt
    23101 tcggcggctg ggtggtggaa tgcttacagg ccgtcaggag taaggggctg cacaatgcca
    23161 gcaggataaa gggtattaaa cgcatcgggt tgatgacctg tcagtaaaaa atgttacatg
    23221 tatatttgtc actctttacg gccacgttca tttacataaa cacggcttat cgtatcgttt
    23281 ttacaccaaa cggcccgcca tgcagttgcg tgcataggca tgcagcgggt tacaatttac
    23341 cgggcgcgtt tccggcggtt ttccgggtgg tttgttgcct gttttatccc gtagccgccg
    23401 gaaacgccct cagaccgtct gagcggtgcg ggcaatgcga cgttatggta aatacccctt
    23461 accggcggcg ctgtggctgc caggtgaagg tggtttccgt agcctcgtat ttctcccgac
    23521 gcatttcctg cgcccgcctg gcttcacgtt cgtcctgaat ggcacgaagc accctttccc
    23581 gcacctgttg ttttaaccgc ctttggcagc gttttgttcc ctttcaggcc catggccagt
    23641 gcctgagcga caaaggcgtc cgccaggcgc ttttcttcag cgggagtcag tttcaggtgc
    23701 gtcatagtgg cctccgggcg tctcaggttt cccgaacagt ttaaccgcag gtcctctcct
    23761 catgccagtt agctttcaga tgtgtctata ccatctgaaa tgtaagtgtg atgaatgtct
    23821 taaataataa aatttgttgc catgagaaat tttcgggaaa agacgcgatc tgcttacagg
    23881 tggctccggg cgcttttttg tgcctgaaga tgagaactaa tctcatatat tgacacctga
    23941 aaa
//
