LOCUS       NZ_CP109935            24652 bp    DNA     circular CON 21-JUN-2024
DEFINITION  Staphylococcus aureus strain SASWT1215 plasmid unnamed2, complete
            sequence.
ACCESSION   NZ_CP109935
VERSION     NZ_CP109935.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN30089067
            Assembly: GCF_030168515.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 24652)
  AUTHORS   Sun,L.
  TITLE     Genomic characterization of healthcare-associated ST5 MRSA causing
            severe pseudomembranous enteritis in intensive care unit
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 24652)
  AUTHORS   Sun,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2022) Infectious Diseases, Zhejiang University, 3
            East Qingchun Road, Hangzhou, Zhejiang 310016, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: unicycler v. 0.4.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_030168515.1-RS_2024_06_21
            Annotation Date                   :: 06/21/2024 03:42:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,975
            CDSs (total)                      :: 2,896
            Genes (coding)                    :: 2,805
            CDSs (with protein)               :: 2,805
            Genes (RNA)                       :: 79
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 51 of 91
            Pseudo Genes (incomplete)         :: 39 of 91
            Pseudo Genes (internal stop)      :: 31 of 91
            Pseudo Genes (multiple problems)  :: 28 of 91
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP109935.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24652
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="SASWT1215"
                     /isolation_source="intestinal mucosa"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed2"
                     /geo_loc_name="China:hangzhou"
                     /lat_lon="30.3 N 120.2 E"
                     /collection_date="2020-12-15"
                     /collected_by="feng zhao"
     gene            join(24632..24652,1..963)
                     /locus_tag="NT398_RS14700"
                     /old_locus_tag="NT398_14705"
     CDS             join(24632..24652,1..963)
                     /locus_tag="NT398_RS14700"
                     /old_locus_tag="NT398_14705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181101.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKDVRFSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            <983..1272
                     /locus_tag="NT398_RS14705"
                     /old_locus_tag="NT398_14710"
                     /pseudo=""
     CDS             <983..1272
                     /locus_tag="NT398_RS14705"
                     /old_locus_tag="NT398_14710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            1819..1968
                     /locus_tag="NT398_RS14710"
                     /old_locus_tag="NT398_14715"
     CDS             1819..1968
                     /locus_tag="NT398_RS14710"
                     /old_locus_tag="NT398_14715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(2136..2828)
                     /locus_tag="NT398_RS14715"
                     /old_locus_tag="NT398_14720"
     CDS             complement(2136..2828)
                     /locus_tag="NT398_RS14715"
                     /old_locus_tag="NT398_14720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            2938..3132
                     /locus_tag="NT398_RS14720"
                     /old_locus_tag="NT398_14725"
     CDS             2938..3132
                     /locus_tag="NT398_RS14720"
                     /old_locus_tag="NT398_14725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            4249..4866
                     /gene="cadD"
                     /locus_tag="NT398_RS14725"
                     /old_locus_tag="NT398_14730"
     ARG             4250..4863
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            4885..5232
                     /locus_tag="NT398_RS14730"
                     /old_locus_tag="NT398_14735"
     CDS             4885..5232
                     /locus_tag="NT398_RS14730"
                     /old_locus_tag="NT398_14735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_100229916.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNDVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            5389..5481
                     /locus_tag="NT398_RS14735"
                     /old_locus_tag="NT398_14740"
     CDS             5389..5481
                     /locus_tag="NT398_RS14735"
                     /old_locus_tag="NT398_14740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(5653..6624)
                     /locus_tag="NT398_RS14740"
                     /old_locus_tag="NT398_14745"
     CDS             complement(5653..6624)
                     /locus_tag="NT398_RS14740"
                     /old_locus_tag="NT398_14745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            6748..7167
                     /locus_tag="NT398_RS14745"
                     /old_locus_tag="NT398_14750"
     CDS             6748..7167
                     /locus_tag="NT398_RS14745"
                     /old_locus_tag="NT398_14750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(7693..8538)
                     /gene="blaZ"
                     /locus_tag="NT398_RS14750"
                     /old_locus_tag="NT398_14755"
     ARG             complement(7697..8538)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            8645..10401
                     /gene="blaR1"
                     /locus_tag="NT398_RS14755"
                     /old_locus_tag="NT398_14760"
                     /pseudo=""
     CDS             8645..10401
                     /gene="blaR1"
                     /locus_tag="NT398_RS14755"
                     /old_locus_tag="NT398_14760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer BlaR1"
                     /name="blaR1"
     gene            10391..10771
                     /gene="blaI"
                     /locus_tag="NT398_RS14760"
                     /old_locus_tag="NT398_14765"
     ARG             10392..10768
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            11035..11628
                     /locus_tag="NT398_RS14765"
                     /old_locus_tag="NT398_14770"
     CDS             11035..11628
                     /locus_tag="NT398_RS14765"
                     /old_locus_tag="NT398_14770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            11600..13042
                     /locus_tag="NT398_RS14770"
                     /old_locus_tag="NT398_14775"
     CDS             11600..13042
                     /locus_tag="NT398_RS14770"
                     /old_locus_tag="NT398_14775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /protein_id="WP_000790712.1"
                     /translation="MKNKEKYLTNFSEAKRKKATQKYNIIKPFILGEQSLSSISKSKGI
                     ALSTLYRWNKSYKEQGLKGLIYATKADKGTRKIEPKIIDEIERLALMNKRNSIATIHRK
                     TTNYCKENNFDIPSYKQIYSVIKAMPKSVIDFSHQGEKYYQNKYDLIQIRESSRPNEIW
                     QADHTLLDIFILDQKGNINRPWLTIIMDDYSRAIAGYFLSFDAPNAQNTALTLHQAIWN
                     KNDTNWPVCGIPEKFYTDHGSDFTSHHMEQVAIDLKINLMFSKVGVPRGRGKIERFFQT
                     VNQTFLEQLPGYINNNDTPSNLINFHNFEEKLRYFLIEDYNQKEHSTIHTTPISRWNSN
                     HFFPNMPSSLEQLDLLLLEIPKSRKVHSDGIHFQGFRYSNTNLAAYVGEYVLIRYNPND
                     MAEIRVFYRDEFLCTAICPEIADYSIDIKDIQHARSQRRKHLKQNIASPSTTELIKEEK
                     NCGYSPQETTKNVKKLKRYRND"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            13035..13793
                     /locus_tag="NT398_RS14775"
                     /old_locus_tag="NT398_14780"
     CDS             13035..13793
                     /locus_tag="NT398_RS14775"
                     /old_locus_tag="NT398_14780"
                     /inference="COORDINATES: protein motif:HMM:NF012464.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000164959.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYTAPAEKQSGKSIENRPVFQEVLN
                     FLRMGDRLIVESIDRLGRNYEEIIQTVNYLKDKEVQLMITSLPMMNEVIGNPLLDKFMK
                     DLIIQILAMISEQERNESKRRQAQGIQVAKEKGIYKGRPVLYSPNAKDPQKRLVYYRVV
                     ELLEQGKSISTIAKEVGITRQTIYRIKNSK"
                     /name="recombinase family protein"
     gene            13854..14168
                     /gene="arsR"
                     /locus_tag="NT398_RS14780"
                     /old_locus_tag="NT398_14785"
     ARG             13855..14165
                     /name="arsR"
                     /gene="arsR"
                     /gene_name="As(III)-sensing metalloregulatory
                     transcriptional repressor ArsR"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="99.04"
                     /coverage="100.0"
     gene            14165..15457
                     /gene="arsB"
                     /locus_tag="NT398_RS14785"
                     /old_locus_tag="NT398_14790"
     ARG             14169..15454
                     /name="arsB"
                     /gene="arsB"
                     /gene_name="arsenite efflux transporter membrane subunit
                     ArsB"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="99.77"
                     /coverage="100.0"
     gene            15475..15870
                     /locus_tag="NT398_RS14790"
                     /old_locus_tag="NT398_14795"
     CDS             15475..15870
                     /locus_tag="NT398_RS14790"
                     /old_locus_tag="NT398_14795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent arsenate reductase"
                     /protein_id="WP_000358995.1"
                     /translation="MDKKTIYFICTGNSCRSQMAEGWGKEILGEGWNVYSAGIETHGVN
                     PKAIEAMKEVDIDISNHTSDLIDNDILKQSDLVVTLCSDADNNCPILPPNVKKEHWGFD
                     DPAGKEWSEFQRVRDEIKLAIEKFKLR"
                     /name="thioredoxin-dependent arsenate reductase"
     gene            16250..16543
                     /locus_tag="NT398_RS14795"
                     /old_locus_tag="NT398_14800"
     CDS             16250..16543
                     /locus_tag="NT398_RS14795"
                     /old_locus_tag="NT398_14800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            16618..18552
                     /locus_tag="NT398_RS14800"
                     /old_locus_tag="NT398_14805"
     CDS             16618..18552
                     /locus_tag="NT398_RS14800"
                     /old_locus_tag="NT398_14805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713731.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTTIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLTLKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTPDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            18556..18867
                     /locus_tag="NT398_RS14805"
                     /old_locus_tag="NT398_14810"
     CDS             18556..18867
                     /locus_tag="NT398_RS14805"
                     /old_locus_tag="NT398_14810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            18879..19505
                     /locus_tag="NT398_RS14810"
                     /old_locus_tag="NT398_14815"
     CDS             18879..19505
                     /locus_tag="NT398_RS14810"
                     /old_locus_tag="NT398_14815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            19743..20386
                     /gene="mobV"
                     /locus_tag="NT398_RS14815"
                     /old_locus_tag="NT398_14820"
                     /pseudo=""
     CDS             19743..20386
                     /gene="mobV"
                     /locus_tag="NT398_RS14815"
                     /old_locus_tag="NT398_14820"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            20453..20953
                     /locus_tag="NT398_RS14820"
                     /old_locus_tag="NT398_14825"
     CDS             20453..20953
                     /locus_tag="NT398_RS14820"
                     /old_locus_tag="NT398_14825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273007.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTYFEKYTKQIKAAQMILD
                     DYEWIKSGKSLKKSEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQE"
                     /name="hypothetical protein"
     gene            21317..22177
                     /locus_tag="NT398_RS14825"
                     /old_locus_tag="NT398_14830"
     CDS             21317..22177
                     /locus_tag="NT398_RS14825"
                     /old_locus_tag="NT398_14830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            22264..22603
                     /locus_tag="NT398_RS14830"
                     /old_locus_tag="NT398_14835"
                     /pseudo=""
     CDS             22264..22603
                     /locus_tag="NT398_RS14830"
                     /old_locus_tag="NT398_14835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(22818..22913)
                     /locus_tag="NT398_RS14835"
                     /old_locus_tag="NT398_14840"
     CDS             complement(22818..22913)
                     /locus_tag="NT398_RS14835"
                     /old_locus_tag="NT398_14840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001002795.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGYWLHKRDKK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            23062..23247
                     /locus_tag="NT398_RS14840"
                     /old_locus_tag="NT398_14845"
     CDS             23062..23247
                     /locus_tag="NT398_RS14840"
                     /old_locus_tag="NT398_14845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466617.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSAWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(23463..24206)
                     /locus_tag="NT398_RS14845"
                     /old_locus_tag="NT398_14850"
     CDS             complement(23463..24206)
                     /locus_tag="NT398_RS14845"
                     /old_locus_tag="NT398_14850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843735.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIRRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     ARG             15476..15867
                     /name="arsC"
                     /gene="arsC"
                     /gene_name="thioredoxin-dependent arsenate reductase"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(7694..8538)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="97.15"
                     /coverage="100.0"
     BGC             11250..21543
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          1329..1476
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          2..963
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="98.0"
                     /evalue="0.0"
     Typing          1095..1264
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
     Typing          21318..22177
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(23464..24206)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          19744..20117
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="4.78e-74"
ORIGIN
        1 gtgcaagaaa attacaaaga aagattttat caaatcccta aagtattctt taccagtgaa
       61 aattataaaa atctaactaa tgatatgaaa atagcctatg ctatcttacg tgatcgctta
      121 aatttatcta ttaaaaatag ctgggttgat gaagatggta acatttactt tgtttattca
      181 aatgaaaagc taatggaaat cttaaattgt aaaaaagaaa agttaacaaa aataaaaaaa
      241 gggttagaaa acgatggtct actcattcaa aaacgacgtg gtttaaataa accaaatatt
      301 ctatatttaa tgaaacctat tgtcacagaa cgtgatattt acaaaataga aaaagaagaa
      361 aacgatgttg aaccttacgg cgagaaggac gttcgatttt cgaacgtcca gaagttcgaa
      421 aatcgaacgt ccagaagttc gaaaatcgaa cgtccagaag ttcgaaaatc gaacactaat
      481 gatactgact ttaatgacat tgactttaat gatactgaga ataatgatat gaatgacttg
      541 aatgatataa agtacaaaaa tgaaattagt aatcattcaa atcattcaaa tcaatttaca
      601 cataattttg atgataaaga aatgctattg caagaattcc cagaacaact aactaattat
      661 ttattaaaat atgattatag agatttagaa atcataaagg ctgttattct taaagcaaaa
      721 aaatcattta attcaaggca tgaagatatg cattacatgt tagaggacat tgaggatgaa
      781 atattaactt ctttaaaaag acttaaaaaa gctatacatg ataggggagt taaaggccaa
      841 aaggaaacaa tcaagtcaat gcaagcttat ttaatgcaaa caattctaac tgaacttgaa
      901 gaaacacatg ccctttatat gcgccgtaaa aacatgaaac aatataatat ctttaatcaa
      961 taattcaaat gattttataa cactcgaaga gacatcaaaa tattccgtta aatcatctga
     1021 ctttttaact gatgacgacg aaaaaaatca agaaattgta agtgatttag aaaaaggttt
     1081 gtatcgaaaa cgtatgttaa gttatggtgg attgcttaaa caaaagcata aaattttaaa
     1141 cttagacgat gccgaagatg gtaatttgat taatacaagt gatgaagata aaacgacaga
     1201 cgaagaaaaa aagcacattc aattaccgca atttggaatt tcgaaaagca aaattattat
     1261 ttaagacatt agtgataact gatgtctttt tttattgttt ttctgtaaaa aagtgctgtc
     1321 ttatttttgt gacaaatgct gtatgtagtg tcacactttt gtgacactac agctttgtat
     1381 gatatcactt taaaataact taaaaccctt ggaatgtctg gccttgccag atctatcatt
     1441 tttgaatgat agcaaatttc ccttatgctc ttacggagat tttagagtta aattaaaatt
     1501 tctaagtttt tgataagaaa agccctgcag gaatttagaa aaacatgggg aagttttaaa
     1561 gtattttatg ctaattttta aatttgcatg taaatgggca gtatctaaaa aattagtcac
     1621 tgattttgct gaaatttttg tttgtgaaat tagcatatat ttatttggct catatttgcg
     1681 ttttaagaga ctgtatagat ttttaagtac aaaacctata tgatttgcct ctaagtcttc
     1741 aaaatgcctc ttaaaatcca aaataaaagt gtttaatatt gtaataagga ttgctatttt
     1801 tataaaagga gagatatcat gaagattaaa actttcgcta cttttactca tcgtcaatta
     1861 gataaacaag ttaataggtt tttaaagaat gatattcatg tattagaaat tcaaacacac
     1921 agtaattggt tatatatttc agctattgtt ttttatgagg ataaataagg aacatcgtat
     1981 ttatgccgaa aaaatttatt gatgttgaga agaaccctta actaaacttg cagacgaatg
     2041 tcggcatagc gtgagctatt aagccgacca ttcgacaagt tttgggattg ttaagggttc
     2101 cgaggctcaa cgtcaataaa gcaattggaa taaaatcaac ctacagagca tccagctgca
     2161 aatgcagttc cgcaaactgc ttcacataca ccgccggcta ttggatttac gattgcccat
     2221 actccacagt agtgagcaca tgcataaagt ccagccatac tacaagcgaa tgctttgccg
     2281 ttccatttga atcctgcata tgttaccggt ctgtttttat caactttttc agccttatat
     2341 tcaacgtaat ttttgttaat aagtattttt ccctctttgt tttcagtcat acttcttttt
     2401 tcggcaatga attttgtgat ttttttgttg tagttatcat atattgtttc agaaactaca
     2461 atttcttttg ttttttcatt tttataagcg ttattagcta tgtagccata tgcattttta
     2521 tcatttgctt ctgtagctag atattttaat ttagaatttt tgtcttctag ctttattttt
     2581 ttaaatcctt cttttttcat ttgcttttcg aatttttgca tatcttcatt tttattttgc
     2641 aattgttcta gaaaacttat ttctttcttg gtcatttgtg atacttcgat gtttttgctt
     2701 ttcaattttt ctttttgatt ttctagtaaa gaactttttt gttcttcatt tgcgtaagca
     2761 ttagaaaaat tcgcgctaaa taccagtagg aacaaggaaa ttattgaaaa taattttata
     2821 attttcattt gatacctcca agataataag atattttaat tgtataagta agcgctttat
     2881 aaaatcaata tttattttaa tatatttata aacatatttt tgaaaggagt ctattttatg
     2941 aatgaaaatt tagaaaaata tataaaaagt ttgccacttt taggtttgtt aattagtatt
     3001 ttgttaattg ttttattctt ttttatttta gatgttgatg aagatttatt cgtggttttt
     3061 ttatactgtt tattgccttt gatagttaat ttgtctattt atggttttta tgtttttgtt
     3121 aaaagaaagt aagattatga ataattttgt ttttaatttg tatgctttga gggggttgga
     3181 aaacggtagg tgtatagatt agatttcttg tttttttgaa acgagtgtga acgagtttct
     3241 tcttgtcttg atttttgata aaaacgccct acaggaattt agaaaaacgt ggggaagttt
     3301 taaagaattt tatgctaatt tttaatttgc atgtaaatgg gcagtgtcta aaaatagtta
     3361 ttgtttttgc tcaaattttt gtttttgaaa atagcatata tttatttggc tcatatttgc
     3421 gttttaaaag catatataag ttttagatat aaaactatat gaatcacccc taaatcttta
     3481 aaatgccctc ttaaaattca aaataagggc ataaaaaata aaagctaccc cagataaagt
     3541 gaggtagctt tttctttcat acggtctatt tatttttctt tcgacgccgt atcgtcgatg
     3601 taattcaaaa aagttatggg ctataaatct acatcacttt ttcaagaatg tagtagcaat
     3661 attcaacgca aattaatttt tataactgct cggaatatct caagccgttt ctttaatttt
     3721 gaaataaaaa aatcgacgaa ggtcgattac gtttttgcac atgtcgattt atccgacgta
     3781 taagtgcgcc cttacgggat ttaactagat tataacgacg aattttagac ctgtaaagca
     3841 ataacaatta ggtctaccag gtagataaag tgtacaaagt agaaccgaaa aagttattta
     3901 ttttgaagat ttttcgtaga tataatttgc taataaactt cctaaaactg aataaagaaa
     3961 aatagttaaa ctcatgtaat cactccataa ttctgaagtg tctccatgtc tacgcataga
     4021 cacgcattta tgccgagaaa atttattgtg cgttgagaag aacccttaac taaacttgca
     4081 gacgaatgtc ggcatagcgt gagctattaa gccgaccatt cgacaagttt tgggattgtt
     4141 aagggttccg aggctcaacg tcaataaagc aattggaata aagcacctat gattatttaa
     4201 aaatataagt tataatacat tcaaaaatat ttttgaatga ggtgtattat gattcaaacg
     4261 gttgttgctg ctgctgttct ttatattgct acagcagttg atttattagt aattttatta
     4321 atattttttg ctagagcaaa gactagaaaa gaatatagag atatttatgt tggtcaatat
     4381 ttagggtcta ttattttaat attagttagt ttgtttttag cttttgtatt aaattatgtt
     4441 ccagaaaagt ggatattagg tttattgggt ttaataccaa tttatcttgg aattaaagtg
     4501 gctatttatg atgattgtga aggagaaaag agagctaaaa aagaattgaa tgaaaaagga
     4561 ttgtctaaat tagttggtac ggttgcaatt gttacgatag caagttgtgg cgccgataat
     4621 attggtttat ttgttccgta ttttgtgaca ttaagtgtta ctaatttatt acttactctg
     4681 tttgtctttt taattttaat tttcttcttg gtgtttactg cacaaaaatt agctaatatt
     4741 ccaggaattg gagaaattgt tgagaaattt agtcgttgga ttatggctat tatttatata
     4801 gctttaggtt tatttattat tattgaaaat gacactattc aaacaatttt aggatttata
     4861 ttttaattta gggtgtgatt ttatatgagt tatgaaaata cttgtgatgt gatctgtgta
     4921 catgaggata aagttaacaa tgctttaagt tttttagaag atgataaatc taagaaatta
     4981 cttaacattt tagaaaaaat ttgtgatgag aagaaattga aaatcatatt atctttgatt
     5041 aaagaagatg agttgtgtgt ttgtgatatt tctttgatat tgaaaatgag tgttgcttca
     5101 acttcacatc atttaaggct tttatataaa aatgatgtac ttgattttta taaagatgga
     5161 aagatggcat attattttat taaagacgat gaaataagag agtttttctc taaaaatcat
     5221 gagggttttt gaaacgagtt tcttcttgtc ttgatactat aaaaaacaaa gttatataac
     5281 ataagacgac ttatcggaag tagatatgct tgtatattca cagatggtat aataatagag
     5341 tcgcctatct ctcaggcgtc aattgacgaa gagaggaggt gcattacttt gctaatcatt
     5401 ttcgttcaca tcatagcacc agtcatcagt ggctgtgctg ttgcgtatta tacttattgg
     5461 cttagtaaac gcaacaaata attaataggc gactttataa gccagcatcg aaaaaatccc
     5521 cacactactg caatagtgtg gggattggtg cattaattgt taatcatttt cgttatataa
     5581 attataacac tggttagtag agaaatgcaa aatgattgaa ttaatagtaa atgtattaat
     5641 gaatactcac acttatactt ttaaaatagt tcttcctaaa tgttgtcctt ttaaaagctg
     5701 atctatcgtt ttatagaatt cttcaaatcc aatttcattg tatagaagtg aatttcctat
     5761 attccattca tttgctaact tactccatat atcttcacgg atattatgat caacatatac
     5821 agaatcaatg ccaattaatt taatacctct aagaataaac ggtaatatat tagcgttaag
     5881 tgaatttcct gctacatttc cacatacagt agcaacacct tgataattta gacgttttaa
     5941 accgtataat gttacattac tccccactgt atctaagaaa taatcaaaaa tacctttttt
     6001 aagcggttta ttatcatctt caattattat tacttgtttt gcacctaatt tttttgcgat
     6061 ttctatttgc ttttcttttc ttacgatagc agtgatattt tcatatccaa ttttatgtaa
     6121 aatttgtata gcaacactgc ccacaccacc tgtagcccca gacactaaaa tttcaggttg
     6181 tgatttgata ttcattccat atttttctag ttcaaaaatt gataatgctg ccgtaaaacc
     6241 ggctgtgcca tataccatag actctttaat agacatttct tggggaatag gaacaatcca
     6301 ctctccaggc acttgtgcat attctgaaaa tccacctgta tgtgtcacgc caacatcata
     6361 accagtaact aatacattat cgccttcttt aaacttatca ttcgaacttg attcaacaat
     6421 acctgcaaaa tctataccag gaatcatagg ataatctcta attacaccgc ctttatattg
     6481 taaagctagc atatccttat aatttattga agagtatacc acttttacta atacatcacc
     6541 cttcgataaa tgagattcat caactttttc tactttataa ctaacatttg atgcactttt
     6601 tctcactact accgcattga acatttacta gccttctttc acaattgttt tgtagaagta
     6661 tgtttttgtt gcaaaactat tttcctacaa aacttatcat gatatgataa gcgagtcaat
     6721 actaatgatt taagagaggt tttagttgtg gaattagata attgtataaa ttatttgttg
     6781 agtacttctc agaatagagt ttttaaacat tttaaaagtt tattaagtcc ctataatatt
     6841 actccagcag aatatggtgt tttgaattgc ttgattaata gtaatttgaa tacacctaaa
     6901 gcgattggta atactttaaa tttagaacct tcaacaatat ctggaatatt agataagatg
     6961 tccaaaaagg atctaataac acgtcaaact gataatgaaa atagaagaac tgtgctaata
     7021 aacagtacaa ataaagcaaa agacttatgg ccaacattag aaaagaaagc ctatcaactt
     7081 aataatcatt acttcgctaa tttaactaat gaagaaactg tagtgtttaa aaagatatta
     7141 ctaaagataa ataaaactac gttttaattt ttacgttatt aaaaagttga agtgcgaatt
     7201 ataatcgagt aaatataaat gatagcttag cttaattata tattaaagcc aactatactt
     7261 ttattcccga aaaacctact atccaaattt ctaagatact ttagcctcta taataaacat
     7321 attgtaatat aatttatgta ttatttaggt ttaccctaat cgagcaataa aaaatacttg
     7381 taaaatgcta ttgtcacttt gcttgatata tgagaattat ttaaccttat aaatgagaaa
     7441 aaagcaacgc actttaaata agatacgttg ctttttcgat tgatgaacac ctataattaa
     7501 actattcatc tattatttat gattttttgt atatacaata tttctagttt gttaaagaga
     7561 attaagaaaa taaatctcga aaataataaa gggaaaatca gtttttgata tcaaaattat
     7621 acatgtcaac gataatacaa aatataatac aaactataag atgttatcag tatttattat
     7681 gcatttagaa tattaaaatt ccttcattac actcttggcg gtttcactta tcaacttatc
     7741 atttggctta tcacttttat tgtctttatt cgtaaaaatg actaaaacaa taggttcaga
     7801 ttggccctta ggataaacaa aagcaacatc atttctagaa gcatatgtta ttgcttgacc
     7861 acttttatca gcaaccttat agtcttttgg aacaccatct ttaattaaag tgtctccgtt
     7921 tttattatta aacattaaat caagtaagaa atttttattt tttttgctta attttccatt
     7981 tgcgataagt ttatttaaag tcttgccgaa agcagcaggc gttgaagtat cttttttgct
     8041 ctttggtgaa tagtaattta attctatctc atatctaact ggatttgtta ctttatctcc
     8101 tagttctttt agacgttgtt taactttttt gattccaccg atttctttta taattttatt
     8161 gtttgctgta ttatcactat atgtcattga agcctcaata agttctttta aagtgatatc
     8221 ttttcctaca tatttttcta aaataggaga ataagcaact atatcatctt tgttaatatg
     8281 tactttttta tttaacttat tataaggtac ttgttctaac aaaatagcac tatttatcgc
     8341 ttttgaagtc gaagcatagg caaatctctt atctgaatta aattttactt ccttaccact
     8401 tttagtatct aaagcataaa caccaatatg agcattatat tttttttcta aatcatttaa
     8461 ctctttggca tgtgaactgt ttgaattaca tgcacttaaa actaaagcaa ttacaattaa
     8521 aaatattaac tttttcaaaa taaaccctcc gatattacag ttgtaatttt tataaatcaa
     8581 taatattaca attgtaatat tgatgtcaat tgtttattat aaatatttga aagaaggtgt
     8641 caaaatggct aaattactaa taatgagcgt agtaagcttt tgttttatat ttctattgtt
     8701 agtatttttt aggtacatat taaaacgcta ttttaattat agtttaaatt ataaagtttg
     8761 gtatctaact atgcttgctg gattaattcc ttttatccca attaaattct cttttataaa
     8821 atttaataat gtgaataatc aagcgcccac agttgaaagt aagtcacacg atttgaacca
     8881 taacataaat accaccaaac ctattcaaga gttcacaaca gatatccata agtttaattg
     8941 ggattcaatt gataatatct gcacagttat ttggatagtt ttagttatta ttttaagttt
     9001 taaatttttg aaagccttat tatatcttaa atatttaaag aaacagtcac tttatctaaa
     9061 cgaaaatgaa aaaaataaaa tagatacgat acttttcaac catcaatata aaaaaatatt
     9121 gtgattcgaa aagcagaggc tattcaatct ccaataactt tttggtatgg gaaatatatt
     9181 attttgattc ctagttcata ttttaaaagt gtaattgata aaagactaaa atatataata
     9241 ctgcatgaat atgctcatgc taaaaataga gatactttac atttaattat ctttaatatc
     9301 ttctctatta ttatgagtta caatccatta gtacatattg taaaaagaaa gataattcat
     9361 gacaatgaag tagaagccga tagatttgtc cttaataata ttaacaaaaa tgaatttaaa
     9421 acttatgcgg aatctattat ggactccgta ttaaaaaccc cattttccaa caaaaatata
     9481 ttaagccatt catttaatgg taaaaaatca ttactcaaaa gtagattaat taatataaaa
     9541 gaagccgatc tgaaaaagca gtcaaaatta attctaattt ttatttgtat ttttactttt
     9601 tttatcatga taattcaaag ccagttttta atggggcaat ccttaactga ttataattat
     9661 aaaaagccct tacaaagcga ttaccaaatt ttagatgaaa gtaaaaattt tggttcaaat
     9721 agtggatctt tcgttatgta cagcatgaag aaagacaaat actatattta taatgaaaaa
     9781 gaaagtagaa aaagatattc tcctgattca acttacaaaa tttatttagc actgtttgga
     9841 cttgaccgtc atattataag tgataaaaat tcacgtatgt catggaatca taaacattat
     9901 cttttcgagt cttggaataa ggaacaagat ttaaatacag caatgcaaaa ttcagttaat
     9961 tggtacttcg aacgtattag taatcaaata ccaaagaact atactgcggc tcaactcaag
    10021 caattaaatt atggtaatga aaatttggga agttataaaa gctattggat ggaagatagt
    10081 ttgaaaatat ctaatcttga acaagtaata gtttttaaaa atatgatgga acaaaataac
    10141 cattttagta aaaaagcaaa gaatcaatta tcttcttcat tattgattaa gaaaaatgaa
    10201 aagtatgaac tgtatgggaa aacaggtaca ggtatagtaa acgggaagta taataatggg
    10261 tggtttgtag gttacgtaat tacaaatcat gataagtatt attttgctac acatttatca
    10321 gatggaaacc cgtctgggaa aaatgctgaa ttaataagtg aaaaaatatt aaaaggaatg
    10381 ggtgttttaa atgaccaata agcaagttga aatatctatg gctgaatggg atgttatgaa
    10441 tataatatgg gataaaaaat cagtatcagc taatgaaatt gtagttgaaa ttcaaaaata
    10501 taaagaagtt agtgataaaa cgattagaac attaatcaca agactatata aaaaagagat
    10561 tataaaacga tacaaatcag aaaatattta tttttactca tcaaatatta aagaagacga
    10621 tattaaaatg aaaactgcta aaacctttct taataaactg tatggagggg atatgaaaag
    10681 tttagtgctg aattttgcga aaaatgaaga attaaataac aaagaaattg aagaattgcg
    10741 agacatttta aatgatatta gtaaaaagta attagaggta tgtttcaaac ataatacata
    10801 tgtaaaccat acttgactct tattaaatta gttttgttaa tgacatttaa aatatattat
    10861 taaagatgag agtgtccaga aaataaccat tttctggaca ctcttctttt atgtctaaat
    10921 aagtaagaat tacataggat tatgtgttca aaaacccaac aaaaaatcta tgttcataaa
    10981 agtccttgta attaagttat ggtacactga agatgtatat aggaggtttg tattttgaaa
    11041 ataggttatg caagagtttc aactggatta caaaatttaa atttacagga ggatcgatta
    11101 aatacatatg gttgtgaaaa gatatttaat gaccatatga gtggttcaaa aagtaaaaga
    11161 cctggtttag ataaagcaat tgaatttgcg aggtcaggag atacgattgt tgtttggaga
    11221 ttagatagat tgggacgtaa tatggaggat ttaatcacat tagttaatga gcttaacgaa
    11281 cgaggtgtaa gtttccatag tttagaagaa aatataacaa tggataaatc aagttcaact
    11341 ggacaattat tatttcattt attcgcagca tttgcagaat ttgaacgtaa tttaatttta
    11401 gagcgttctt cagctggccg aattgcagca cgtgctagag gccgatatgg aggcagacca
    11461 gaaaaattaa atcaaaaaga tttaaactta cttaagacac tttatgataa tggcacgcca
    11521 attaagacaa ttgcagaaca gtggcatgtt tcacgtacaa caatttatcg ttacctcaat
    11581 aaattggagg acaaggaaga tgaaaaacaa ggagaagtat ctaactaatt tttctgaagc
    11641 caaacgtaaa aaagctactc aaaagtacaa tattataaaa ccttttatcc taggcgaaca
    11701 atctttatca agtatttcta aaagtaaagg gattgcgtta agcacccttt atagatggaa
    11761 taagtcatat aaagaacaag gacttaaagg actaatctat gcgacaaaag ctgataaagg
    11821 aacacgtaaa atagaaccaa agataattga tgaaattgaa cgccttgcgc ttatgaataa
    11881 aagaaatagt atagccacaa ttcataggaa aaccactaat tactgtaaag aaaataattt
    11941 tgatatacca agttataaac aaatttatag tgttattaaa gcgatgccta agtctgttat
    12001 tgatttctct catcagggtg aaaaatacta tcaaaataag tacgatttaa tacaaattag
    12061 agaatcctcg agacccaatg aaatatggca agcagaccat actttgctag atatctttat
    12121 attagaccaa aaaggtaata tcaatagacc atggctaact attattatgg atgactatag
    12181 tcgtgcaatt gcaggctatt tcttaagttt tgatgccccc aatgctcaaa acacagcatt
    12241 aacactacac caagcaatat ggaataaaaa tgataccaat tggccagtgt gtggtatacc
    12301 cgaaaaattc tacacagatc atggaagtga ctttacttca catcatatgg aacaagtcgc
    12361 tattgatttg aaaattaact tgatgttttc gaaagttggt gttcctcgtg gtcgtggaaa
    12421 aatagaacga ttctttcaga cagttaatca aactttctta gaacaactgc ctggatatat
    12481 aaacaataat gatactccta gtaatctaat aaattttcac aattttgaag aaaaattacg
    12541 ttacttttta attgaagatt ataatcaaaa agaacatagt actattcata ccacgcctat
    12601 cagtcgttgg aatagtaatc actttttccc taatatgccg agtagcttag aacaacttga
    12661 tttattattg ttggaaatac ctaaatctag aaaagttcat tcagatggca ttcattttca
    12721 aggttttcga tacagtaata ctaatctagc agcttatgta ggtgaatatg tactgattcg
    12781 ttataaccca aatgatatgg ctgaaatacg tgtgttttat agagatgaat ttctttgtac
    12841 tgctatatgt ccagaaatag ctgattactc catagatata aaagacatac agcacgctcg
    12901 tagtcagaga agaaaacact taaaacaaaa tattgctagt ccaagtacca cggaattaat
    12961 taaggaagaa aaaaattgtg gttattcacc tcaagaaacg actaaaaacg tcaaaaaatt
    13021 aaagaggtat cgtaatgact aaaaatcaaa atttcattga aacgaaagag tataaacgct
    13081 ttgctgaatt ttgtgatgct tgtattaaat atcagtatat tggtatatgt tatggtcaac
    13141 ctggtgtcgg aaaaacttta tcgtctaggt attacacaaa ttgggatact attgaaaaac
    13201 aagttaacca tagaggttgg gaagatttag ctagtaaaac gaccgatgac atactatcgg
    13261 tggataaaat attttatact gcaccagcag aaaaacaatc aggtaaatct atagaaaaca
    13321 gacctgtttt tcaagaagta ttaaattttt taagaatggg agatcgttta attgttgaat
    13381 ctattgatag actaggaaga aattacgagg aaataattca aacagttaat tacttaaaag
    13441 ataaagaagt tcagctcatg ataacgagtt tacctatgat gaatgaagtc attggaaatc
    13501 cactactaga taaatttatg aaagatttaa ttattcaaat tttagcaatg atttcagaac
    13561 aagaaagaaa tgaaagtaaa cgtcgacaag ctcaagggat tcaagtcgcc aaagaaaaag
    13621 gtatatataa agggagacct gttctgtatt ctcccaatgc taaagaccca caaaagcgtt
    13681 tagtttatta ccgagttgtt gaattacttg aacagggtaa atctataagt actatagcta
    13741 aagaagttgg tattacacgt caaactatat atagaataaa aaatagtaaa taaaataaca
    13801 tagacaataa tctatataga tgttaatcta tttaatatct aggaggttta ttcatgtctt
    13861 ataaagaact atcaacaata ttaaaaattt tatcagatcc aagtaggtta gaaatattag
    13921 atttactttc ttgtggtgag ctatgcgctt gtgacttatt agaacacttt caattctcac
    13981 aacctacact aagtcatcat atgaagtcat tagtagataa tgaattagtt acaacacgaa
    14041 aagatggcaa taaacattgg tatcaactta atcatgctat tttagatgat attatccaaa
    14101 acttgaacat cattaataca tctaatcaaa gatgtgtatg taaaaatgtg aaatcaggtg
    14161 actgttgatg actattttag caattgtaat ttttctttta actttaacct ttgtgatttg
    14221 gcaaccaaaa ggtttagata ttggtattac agctttaatt ggagcggttg ttgctatcat
    14281 tacaggagtc gtaagtcttt ctgatgtatt agaagtaaca ggtattgttt ggaatgcaac
    14341 tttaactttt gtggctgtta ttcttatttc attaatatta gatgaaattg gtttttttga
    14401 atggtctgcg atacatatgg tcaaggcttc aaacggtaat ggcttaaaaa tgtttgtttt
    14461 tattatgtta cttggggcaa ttgtagcagc atttttcgca aatgatggtg cagctttaat
    14521 cttaacgcct attgtattag cgatggtaag gaatctagga tttaatcaaa aagtgatttt
    14581 cccctttatt attgccagtg gttttattgc tgatactaca tcacttccct taattgtaag
    14641 taacttagtt aatatcgttt ctgcagatta cttcgatatt ggatttattg aatattttag
    14701 ccgaatgatc attcctaata tattctctct gattgctagt attctcgttt tatggttata
    14761 tttcagaaaa tccataccta aaacgttcga tacagaaaat ctatcagatc ctaaaagtgc
    14821 aattaaagat tctaagttat ttaagctttc atggatagta ttagcagtac tactcgttgg
    14881 atatcttgtt agcgagttta tccaaattcc tgtatcaatt attgctggta ttattgcttt
    14941 tatctttgta atattagctc gtaaatctaa agcagttcat acaaaacaag tgattaaagg
    15001 tgcaccatgg aatatcgttg tattctctat tggtatgtat cttgttgtgt ttggactaaa
    15061 aaatgtaggt attacaacgg tccttgggga tgttttaaca aacatttcaa attatgggtt
    15121 atttagcagc atcatgggta tgggctttat agctgctttc ttatcttcga ttatgaacaa
    15181 catgccaact gttttaatag atgcaatagc gattggccaa tccagtgcta caggaatatt
    15241 aaaagaaggc atggtttatg cgaatgtcat aggttctgat ttaggaccta aaattacgcc
    15301 aattggttct ttagcaacat tattgtggct acatgtctta acacaaaaag gtgtgaagat
    15361 ttcgtgggga acatacttta aaactggaat tatcatcact attccagtcc tatttgtaac
    15421 actcttaggt ttatacctta cactaatcat attttaagaa aaggggcttt aattatggat
    15481 aagaaaacaa tttattttat atgtacagga aactcttgtc gtagccaaat ggctgaaggt
    15541 tggggaaagg aaatattggg tgaaggttgg aatgtctatt ctgctggtat tgaaacacat
    15601 ggtgttaatc ctaaagcaat agaagctatg aaagaagtag atattgatat atcaaaccat
    15661 acgtcagact tgattgataa tgatatttta aaacaatcag atttggtcgt aacgttatgt
    15721 agtgatgcag acaataattg tcctatttta ccaccaaacg ttaaaaaaga gcattggggt
    15781 tttgatgatc cagcaggtaa agaatggtca gaattccaac gtgttagaga cgagattaaa
    15841 ttagctatag aaaagtttaa attgagataa tcataaacac ctcttattta gttaataaga
    15901 ggtgttttgc catttaaaga acaaaatttg tgccatatac aatatgccct ctctttttct
    15961 cattaacgaa cgtttataac gcaatcatga tgagagtatt aatacagtta attatttgaa
    16021 atactttagt ttacataatg ttgaattata ggtagtgaaa ttgtatttat tatacattgt
    16081 catatcgttg tttaatgata gttaatttaa ggataataga attaatatta tatatagatg
    16141 aacaaaacaa gcaacagagc aaaaaaacac ttttagatta tttttactca ttctctattt
    16201 tatttatttt tgctataata aataaataat attaaatgga ggtgttttta tgaaaaagaa
    16261 atttgtttct agttgtattg ctagtacaat cttattcggc actttattag gtgtaactta
    16321 taaagctgaa gctgcaacag tacatgtagc tggtggtgtt tggagccatg gtattggaaa
    16381 acattacgta tggtcttatt atagtcacaa taaaagaaat catggttcaa cagcagtagg
    16441 gaaatattca tcttttagtg gtgttgctcg acctggtgtt caatctaagg catctgctcc
    16501 aaaggcttgg ggtggaaaca aaacatttta tagtcttcac taattacata tattaattaa
    16561 ggagaataga cagaattaag taaacttaat tctgtctatt ctcttgaaag aggcaatatg
    16621 aaaaaattca aattattttt agattttagt actttattat taatttcagg gctattattt
    16681 ttatttttct tcaaagaaaa tgaagaaatt atacctgaaa gttccaatat tttaacaatc
    16741 tctaattggg ataaatctaa cagtaaatca aaagtgttag atgtcattga atcaggcgcc
    16801 aaaaatcaaa atatacaaat aattaaatcc gttaaagatt ttgataataa aaaagaattt
    16861 tttgttttca actcaaaacg aaataattct gactttatac gtaataaaac atcactttta
    16921 actccatcag atttattaaa cagagagata aaaggaaagt attatattat tggcgaacat
    16981 ttcaatgtag aagagcttac gagtgaatta aaaaaagctg gtttaacatc tgaagttgaa
    17041 tacataaata gaaacatatt attttttgaa ttagtcatag ataatgattt attagtgcct
    17101 ttcatattct taggcgtatt atatcttttg tacttcttat atgacagagg atataatttg
    17161 aaattttatg ctattcaaaa gctacatggc ttttcaacta cacgcattat ttttcataat
    17221 attcatataa aaatcattta ttggctagta cttaccacta ttttctttat tgctaatata
    17281 ttaatcattc atatagccaa tttagaattg gatttcttaa tgtttattcg tagatttatc
    17341 gtgttgcttt ttgtttttgc ttgtattact acattgttgt ggctgatttc gtatagtctt
    17401 cttttgaagt taagtattcc attaacctta aaagggaaaa aaggatataa gttttcaata
    17461 tttatgggta ccttcaccaa atgtatcatg gtgctaatac tatctttttt actggcacaa
    17521 aatttaaatg cttatacgaa gttaaagaat atatatgact ctgaaaaaat ctggcaaaag
    17581 ttagataatt actatacatt agagatttct cctaatatta gaaattcaga agaaaaacaa
    17641 attttagaaa ctaatatata caatttaatt aagaaaagcg aacaacttgg tggattgctt
    17701 ttaaagaata ataatatagc caatcccgat aaaaacaatt acattcctga aaatggcaat
    17761 gtctttttta tcaataacaa ttttctgaat ttctataaaa atataaatca tgattttaaa
    17821 atgattgaca atcattcgga taaaataaac gtgtttattc ctccaaggtt acaatatcaa
    17881 aaatctgaaa ttcaaaaaaa tcaccaagga tggattgact ttcaaaagca acaaaacaaa
    17941 aaagtagatg tgcaagtact gtcaaaaaac gtatctgttt tttcttttga tcgcacaact
    18001 aatttgaaat ttggatatct agattctcca atagtaatgt tgttgacacc tgacgattta
    18061 acaggagatt tttatttagc tgctgtttct caaggtggat atctatttaa agatttagat
    18121 acacttaaac agttgcttaa agataatcac ctagaagaag aaattagcgg tataactaat
    18181 tacaaggatt ctgtgttaaa tgaattaaat gaaacgaaaa caaaaatgat aataacaata
    18241 gttactatta ttattaacgt tttcattctt ttgatagcta ctgtatttga aacaattcaa
    18301 tattttagct ggaataaaaa gcaactatta ttaagaaaaa ttcatggtta ttcattattc
    18361 agcagtaatg tacgttattt aacaatttct attttacttt ctattatgtt agcttacact
    18421 acgcatattt tatttggttc aaagatatta ctattcataa taatgtctat tgctattatt
    18481 caacatttac ttcaaattgc ttatattaaa tatcttgaaa aatactttaa agatttaatg
    18541 agggagattt aaacaatgaa aagaacttta attattgtaa caattgtact attaatcatc
    18601 atacttagtc tgttattggt tagaaatgag catttagatc gttttaaccc actgttaaaa
    18661 gaaaaagtat cttatgccaa agttccaaaa gatacccagg actatagaaa tataactgta
    18721 tactctaaaa atggagaaaa aaagagttat aaattggatt ttttaggtta tgatcctaca
    18781 aaagaatatg tgaaagtaaa tcataaaggg aaatatgtgc gttcgataga atacattaca
    18841 aaagatattc ctagcttttt aaaatgaggt gaccgatagt gataaaactt gaaaatgttt
    18901 ttgtaaaaaa aggtaataaa aacattttag acggatgtaa ctttaatttt gaaaaaggaa
    18961 aatcatatgc tttagttgga gaaagtggcg ctggaaaatc tactttactt aacataatcg
    19021 ctgggttcga agatgtatca caaggaagca tatatattga agataagtta ctaaaaaaga
    19081 aagtcgattt ttatagatat acgttagggt atttgtttca aaattttgct ttacttgaaa
    19141 atcaaacaat cagtcaaaat ttagatttag ccctaaagtt caaaaagaat aaaaaagata
    19201 atatgaactt aaagaaagaa gtattaaaaa aggtcggcct agatttagat atcaagagaa
    19261 ttgttagttc tctaagcggt ggtgaacaac aaagagtagc attggcaaga ttaatattaa
    19321 aagatccgaa aatcatttta gctgatgaac ctactggatc actagatacg aaaaatggaa
    19381 aaatagttat tgatttatta ttgaagctac ttgatgaaaa taaaactatg attgtcgtaa
    19441 cgcatgattt agagcttgcg aaacgatttg atgtcatagt caatatttct gagcttagaa
    19501 gttaagaaat attgataggt atagccatac atagagaaaa aacaatatga aatatgatta
    19561 gtcattactt ttgagttttt taatttaagg actggatttt ccagtccttt tttgtgatga
    19621 caaaaaacaa gcctcgcaga gcacacgttt ttaatgactt atttggtttt taataagtct
    19681 agtatgttaa aacttttctg tgtttaggtg ttataatcat atgcagtgga agttgattta
    19741 ttatgtctta ttcaattatt cgagttgtta aagtgaaatc aaaaacaaat acaagaggta
    19801 ttcaaagaga aaataaaaat tatgaaaata tagatattga tttaagtaag tcatatttaa
    19861 actatgattt agtcaatgat actaagtttg attttaataa aaaaattgat gagaaaatcg
    19921 aaaaaaatta taaagggaaa cgcaaaatta gaacagatgc cattaaacat attgatggat
    19981 taattacatc agataatgtg tttttaatca attatctgaa gaagagacaa aatagttttt
    20041 taagcatgct aaagcgttct tggaagaaga atacggtaaa gaaaatcttt tatatgcgac
    20101 agtacatatg gatgagataa caccacatat gcattatggc gtaattccta ttactaaaga
    20161 tggacgttta agtgcgaaag aagttgtagg taataaaaaa gcattaaccg aattccaaga
    20221 tagattcaat acgtatatta ataagcaagg ctatgattta aaacgaggaa tttctagaca
    20281 acttacaaaa gaaaaacatg atcaagttag cggctataaa caaaaaacag aatatcataa
    20341 acaaatgtat atgcgcgaga agcaaataga ggatcattta aagtgagaaa atgataaatt
    20401 gatacaaaac taccaaaaat cattagatac gcttaaaaag cttctgagtg tcatgtatga
    20461 aattaaaact aaaaatgtag gtggatggtt tcataaagag aagcaagaaa caggcaatat
    20521 tgtaattact aaaacttatt ttgaaaaata cactaaacaa attaaagcag cacagatgat
    20581 attagatgat tatgaatgga ttaaaagtgg gaagtcatta aaaaaatcag agaaacaaaa
    20641 tgaaagttta gttaatgaat tgactagtgt ccatatggaa aatgaaaagc tggttgaaga
    20701 atttaatgat ttagcacaac gttataatta tttgttgtca gagaatgaaa agaaagataa
    20761 agaactaaat tatacgctta agttattcaa tcaagttttt aaaatcatta aaagtatgat
    20821 gaaagaagag cgttatcata cgctaataaa tcatattgat aatcatttag acaattctaa
    20881 aatacgtgaa gtaatgacga tagataacaa tgatgaacag ttctttaaga agaaatatca
    20941 agcacaagaa tgagaaatca tttttaaaga agatagagaa gatggttata cattataaaa
    21001 atagatattt aaatgcattt gtttgaggtt aattattttt taggatgaaa aataggtagc
    21061 ccccctctaa ctttttaata tatttttata aatcttttta aaaacctttt taggggcttg
    21121 ttcagaccta gagcaacaag ggatttcaat gcctaaagga gtgtttttgc cacataaaag
    21181 gagtgtttta aaaagttgta ctccttttat ggtttgacat tgataataaa gtagtttatt
    21241 gtgaataaaa gttttcaaat gggagtgtat attcaaacga tactccttta ggttcgtaat
    21301 aaaggggggc tgtatcatga caggagagac agttgtatat aaaaatgaaa tgaatttagt
    21361 tccattaagg cgatttacag ctactgaaat taatttattt tttgcgatgt gtaataaatt
    21421 aaaagagcaa gatactaata cattacgttt gtcttttgat gaattaaaaa aattaagtaa
    21481 ttatagtcca gaaacacgta atattaatag atttgctaat gatttagata atgtgtataa
    21541 aaagatgttg aatttaacca ttagatatga agatgatgat gtaatagaaa gattcgtttt
    21601 attcaatcat tatagaatcc ataagcgaga acaatatcta gaaatatcaa cttcttcaaa
    21661 tttaaaacac atattgaatt caattactaa taattttaca aaatttgaat taaaagaaat
    21721 gactaggctt aaatctacat attctaaaaa tatgtttaga ttacttaaac aatacaaaca
    21781 tacaggctat ttaaaaattc acatcgatga ttttaaaaat cgtttagata tacctaaatc
    21841 ttatcgtatg actgatatta acaaaaatgt ttttaaacct attattattg aattaggttc
    21901 tatatttaat aatcttacta tcaataaaat caaagcgaaa aaagggcgta aaattgaatg
    21961 gatagagttc acatttgacg ctgagaaacg cattcataac aaacgacaac ctcaaatgtc
    22021 caagatagat aaatcaagac aatatgtgag gcgtgaaaag acgcctaaat ggttagaaga
    22081 acggtcatat gaaaagcaac ctcaaaaaga ttacgaccca caattagaga aagaacgaga
    22141 ggatttttta aaacaacttg aactgaattg ggaataacgc aacttttcgt tgcgagttgg
    22201 ttaactaaaa gtatcgtgac ttttcaatta ttttaattat agtttgagtt aaggagtgat
    22261 tttatgaaat tagctgaagc tataaaagaa cagagagaat taaaaagatg gtctcaagag
    22321 gaattagcca atatattaaa ggtttccaga caaagtgttt ctaaatggga aagtgccaaa
    22381 aactatcctt ccttagatat tttgattgct atgagcgatt tatttggaat ctctttagag
    22441 catttaatta aaggagatgc acgttttaaa aaagttattt tagagggaaa ttatagagag
    22501 taacagggca ccttccatag ttgattttct ttatgatttt tggtggcttt tctttcctgt
    22561 tgccggattt ttagtttggg ccattcattc gttcatgggt tgattttaaa atcaaaattt
    22621 aatgcacatc aggcaatatg aaaaaggaaa gtatttttac gacaccttga aatgtattga
    22681 taagaataga agagtttaca aaaggcaata tgaaatatat actaaaagta acaagaattt
    22741 cgtttgtaaa cgcaccaaac cccgaactat tcgccgtagt tcggggtttt ttggtgaatt
    22801 ggctttaatc gtctatatta ttttttatca cgtttatgga gccaataacc aaataacgta
    22861 acgagacaac cactgattgc cgttgtcatg atgtgaacaa gaatttcatt cataaatcgc
    22921 acctcctctc tacgccgaat tgacgtctga gagatagacg accttcacat tataacaaat
    22981 ctcttcttcc atgaaataac atgaatatta ataaatgttg ttatatatta aagataaata
    23041 aatataaggg tgggattgat aatgtttggc gatcaaagac aagaagctac aaaatatgtc
    23101 attaaagaag gttatcaaga tatttatttc ctcaacaaaa acggggaatg gtattatttc
    23161 gaagtaagaa gtgcctggcg tggcaaacat attattagag ttaaagatgg tttgttaggt
    23221 tggagaaaag aaatagtaac tgaataaaga tacaaaatac ttgccaatgc aaaagaatga
    23281 aaacgcgtca aatcaacgat gtataaaaga tgcataaaag ataatgaaag taaaaagcca
    23341 taaatgccta tatgacggca tttatggctt tttgtttggt taacataatc gatgattacc
    23401 agaagttctc actatataaa agacactaaa attttataac ttttagtgcc taatcaatta
    23461 ttttagctac caaacaaacg actccaaaac ccctttttag gttccgtttc ttcactcttt
    23521 tcttctatat cactatcatt gtcatttaga ttagctggaa cgtcttcttt ttttgcttct
    23581 tcaccttgtg tactttcgtc gctttgactt ccagatatat ccttatattg aatctctgtt
    23641 tctttagttt cttcctgatc tctgttaata tttacaggat tagtagtata tgttttttct
    23701 tgtgcatcaa cgttttgtct agtgttagta gatgtatcaa agggataatt aaggtgtttt
    23761 tctttttcta attgattttc taatttttga atctttttat tactctctaa tgccagaact
    23821 tgctgatttt caagcaattt tgatctttct tgcaactctt ttctgtaaaa ttcaattgtt
    23881 gtttcatgac gactttcttg tttttcaatt tgattattta aagtatcaat ctgattttta
    23941 aggatttcta ctatttgagc atcgcttttc gattcaaaat taatattatc cgaccctttt
    24001 ttttgtttgt cttcagtagt actttcaaaa ccatatttct ttttattttc atttactctt
    24061 cgaatgattt tttctatatc ggtatcttct ttaataaacg aagtgttttc ctgttttatt
    24121 gtctctatat tcaatcgctt aatattatta aaaatcgttt gcttactaac ccctaattct
    24181 tcactcaact ttttcacact tttcatatca tcaacccttt ataaaatgtt tataaaccct
    24241 tgataaaata ttataagctt ataatgctta ataataaagt gattaataaa taaaaataaa
    24301 catccatcaa cctttttatc aagggtttat gaaaggttta tgatatttat caagggttta
    24361 taaacccttg ataaagctat attttccctt ttataagttt atttaaagtg ctataataaa
    24421 cttaatataa caaaaacccc aactactggt aatagtcggg gtttggtaat aaaacgttta
    24481 gaaactgttt atttatataa ttttcgatac ttgtattata taatgaataa tatcttagtg
    24541 caagcaccta aatcattaaa taaatgtaaa gctaaataaa aacgttttat tacctcttac
    24601 caaactaaaa tatggaaaga ggttttttgt catgcaaaat caatatttta ca
//
