LOCUS       NZ_CP109934            28243 bp    DNA     circular CON 21-JUN-2024
DEFINITION  Staphylococcus aureus strain SASWT1215 plasmid unnamed1, complete
            sequence.
ACCESSION   NZ_CP109934
VERSION     NZ_CP109934.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN30089067
            Assembly: GCF_030168515.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 28243)
  AUTHORS   Sun,L.
  TITLE     Genomic characterization of healthcare-associated ST5 MRSA causing
            severe pseudomembranous enteritis in intensive care unit
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 28243)
  AUTHORS   Sun,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2022) Infectious Diseases, Zhejiang University, 3
            East Qingchun Road, Hangzhou, Zhejiang 310016, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: unicycler v. 0.4.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_030168515.1-RS_2024_06_21
            Annotation Date                   :: 06/21/2024 03:42:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,975
            CDSs (total)                      :: 2,896
            Genes (coding)                    :: 2,805
            CDSs (with protein)               :: 2,805
            Genes (RNA)                       :: 79
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 51 of 91
            Pseudo Genes (incomplete)         :: 39 of 91
            Pseudo Genes (internal stop)      :: 31 of 91
            Pseudo Genes (multiple problems)  :: 28 of 91
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP109934.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..28243
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="SASWT1215"
                     /isolation_source="intestinal mucosa"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed1"
                     /geo_loc_name="China:hangzhou"
                     /lat_lon="30.3 N 120.2 E"
                     /collection_date="2020-12-15"
                     /collected_by="feng zhao"
     gene            1..936
                     /locus_tag="NT398_RS14555"
                     /old_locus_tag="NT398_14560"
     CDS             1..936
                     /locus_tag="NT398_RS14555"
                     /old_locus_tag="NT398_14560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001829877.1"
                     /translation="MPNFEKYNLSQVKTERFYQLPKYLFEDAYFKKMSAEAKIMYALLK
                     DRFELSIQNEWVDKNNNIYFIFSNKHLCEYLGYAEQKIIKLKKELISFNLLTQERVGLN
                     KPNRLYLLKPNYDIKASHSKELPNSQFQNNEFGSSRTVNLSGQELPNSQSNDTENNDTD
                     YIKTESNDTNDLNDNKLTFPSNHTNHSNHNNSNFNNEALKFQLLEELPQSIQRYLSNFS
                     VNEIKIIKPVLLKAKTSFNNSIDTYYLLEDMEIEILHVLKRFKAMLIQKNETVEAMQGY
                     LMKSLKSEFAEMHTLNKRRDHLPITSLFNQ"
                     /name="replication initiator protein A"
     gene            2782..3318
                     /locus_tag="NT398_RS14560"
                     /old_locus_tag="NT398_14565"
     CDS             2782..3318
                     /locus_tag="NT398_RS14560"
                     /old_locus_tag="NT398_14565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_001829875.1"
                     /translation="MISNKLKSARLAKELTQSEVAKKLYVTRQTVSRWEQGKTLPNIYV
                     IQELSDLYDISLDELVVNTALENKEAKSMKNVNPFALFGAILFNVFLFSLIVIFFGGFL
                     LLSLFISLAMLFSPLILAIFVLTGVQEFNVIQLVMTVIFVVIGLLSIPLLKKVSVFLFK
                     FFKRYLKFNHKAIFY"
                     /name="helix-turn-helix domain-containing protein"
     gene            3472..3567
                     /locus_tag="NT398_RS14565"
                     /old_locus_tag="NT398_14570"
     CDS             3472..3567
                     /locus_tag="NT398_RS14565"
                     /old_locus_tag="NT398_14570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_014287283.1"
                     /translation="MSEIFVNIMTTAASGCLVALFAHWLRKRNDE"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            3980..4825
                     /locus_tag="NT398_RS14570"
                     /old_locus_tag="NT398_14575"
     CDS             3980..4825
                     /locus_tag="NT398_RS14570"
                     /old_locus_tag="NT398_14575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829879.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="WP_217659102.1"
                     /translation="MDLVENCNTFLSFVTNRRMDKKKLYKSNPCKNRFCPMCAWRKARK
                     DALGLSLMMQHIKQAEDKQFIFLTLTTPNVTSEHLESEIKHYNQSFRRLSNRKHFKSIA
                     KGYVRKLEITYNKKCDDYNPHFHVLIAVNKSYFKDTKAYITQKEWLEMWRDVTGNSEIT
                     QVHIQKVKQNNNKELYEMAKYSGKDNDYLINQKVFDAFYKALKGKQVLVYSGLFKDARK
                     KLKNGELDYLKEVDPTEYIYQIFYTWNKKEYLASEIFDLTESEKQEINHQMIDEIEEEK
                     "
                     /name="protein rep"
     gene            complement(5674..6159)
                     /gene="lnu(A)"
                     /locus_tag="NT398_RS14575"
                     /old_locus_tag="NT398_14580"
     ARG             complement(5678..6159)
                     /name="lnu(A)"
                     /gene="lnu(A)"
                     /gene_name="lincosamide nucleotidyltransferase Lnu(A)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            <6631..7107
                     /locus_tag="NT398_RS14580"
                     /old_locus_tag="NT398_14585"
                     /pseudo=""
     CDS             <6631..7107
                     /locus_tag="NT398_RS14580"
                     /old_locus_tag="NT398_14585"
                     /inference="COORDINATES: protein motif:HMM:NF013603.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            7267..8037
                     /gene="aadD1"
                     /locus_tag="NT398_RS14585"
                     /old_locus_tag="NT398_14590"
     ARG             7268..8034
                     /name="aadD1"
                     /gene="aadD1"
                     /gene_name="aminoglycoside O-nucleotidyltransferase
                     ANT(4')-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            8317..8991
                     /locus_tag="NT398_RS14590"
                     /old_locus_tag="NT398_14595"
     CDS             8317..8991
                     /locus_tag="NT398_RS14590"
                     /old_locus_tag="NT398_14595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_044124596.1"
                     /translation="MNHFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            9025..9951
                     /locus_tag="NT398_RS14595"
                     /old_locus_tag="NT398_14600"
     CDS             9025..9951
                     /locus_tag="NT398_RS14595"
                     /old_locus_tag="NT398_14600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277654.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="WP_049883636.1"
                     /translation="MFFTLQQNHHDLDNFSKTGYSNSRLDAHTVCISDPKLSFDAMTIV
                     GNLNRDNAQALSKFMSVEPQIRLWDILQTKFKAKALQEKVYIEYDKVKADSWDRRNMRI
                     EFNPNKLTRDEMIWLKQNIISYMEDDGFTRLDLAFDFEDDLSDYYAMSDKAVKKTIFYG
                     RNGKPETKYFGVRDSNRFIRIYNKKQERKDNADAEVMSEHLWRVEIELKRDMVDYWNDC
                     FSDLHILQPDWKTIQRTADRAIVFMLLSDEEEWGKLHRNSRTKYKNLIKEISPVDLTDL
                     MKSTLKANEKQLQKQIDFWQHEFKFWK"
                     /name="replication initiation factor domain-containing
                     protein"
     gene            10113..11492
                     /gene="tet(K)"
                     /locus_tag="NT398_RS14600"
                     /old_locus_tag="NT398_14605"
     ARG             10114..11489
                     /name="tet(K)"
                     /gene="tet(K)"
                     /gene_name="tetracycline efflux MFS transporter Tet(K)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            11681..12907
                     /gene="mobV"
                     /locus_tag="NT398_RS14605"
                     /old_locus_tag="NT398_14610"
     CDS             11681..12907
                     /gene="mobV"
                     /locus_tag="NT398_RS14605"
                     /old_locus_tag="NT398_14610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016913210.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="WP_049426404.1"
                     /translation="MSYSIVRVSKVKSGTNTTGIQKHVQRENNNYENEDIDHSKTYLNY
                     DLVNANKQNFNNLIDEKIEQNYTGKRKIRTDAIKHIDGLITSDNDFFDNQTPEDTKQFF
                     EYAKEFLEQEYGKDNLLYATVHMDEKTPHMHYGVVPITDDGRLSAKEVVGNKKALTAFQ
                     DRFNEHVKQRGYDLERGQSRQVTNAKHEQISQYKQKTEYHKQEYERESQKTDHIKQKND
                     KLMQEYQKSLNTLKKPINVPYEQETEKVGGLFSKEIQETGNVVISQKDFNEFQKQIKAA
                     QDISEDYEYIKSGRALDDKDKEIREKDDLLNKAVERIENADDNFNQLYENAKPLKENIE
                     IALKLLKILLKELERVLGRNTFAERVNKLTEDEPKLNGLAGNLDKKMNPELYSEQEQQQ
                     EGSVAKLNL"
                     /name="mobV"
     gene            12937..13611
                     /locus_tag="NT398_RS14610"
                     /old_locus_tag="NT398_14615"
     CDS             12937..13611
                     /locus_tag="NT398_RS14610"
                     /old_locus_tag="NT398_14615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            13919..14536
                     /locus_tag="NT398_RS14615"
                     /old_locus_tag="NT398_14620"
     CDS             13919..14536
                     /locus_tag="NT398_RS14615"
                     /old_locus_tag="NT398_14620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="WP_049394661.1"
                     /translation="MIQTIVTAAILYIATAVDLLVILLIFFARAKTKKEYRDIYIGQYV
                     GSVALIVVSLFFAFVLNYVPEKWILGLLGLIPIYLGIKVAIYDDCEGEKRAKKELNEKG
                     LSKLVGTVAIVTIASCGADNIGLFVPYFVTLSVTNLLITLFVFLILIFFLVFTAQKLSN
                     IPGVGEIVEKFSRWIMAVIYIALGLFIIIENDTIQTILGFIF"
                     /name="CadD family cadmium resistance transporter"
     gene            14555..14902
                     /locus_tag="NT398_RS14620"
                     /old_locus_tag="NT398_14625"
     CDS             14555..14902
                     /locus_tag="NT398_RS14620"
                     /old_locus_tag="NT398_14625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_002441960.1"
                     /translation="MSYENACDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKISVASTSHHLRLLYKNDVLDFYKKGKMAYYFIKDDEI
                     KEFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            15071..15172
                     /locus_tag="NT398_RS14625"
                     /old_locus_tag="NT398_14630"
     CDS             15071..15172
                     /locus_tag="NT398_RS14625"
                     /old_locus_tag="NT398_14630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_000228874.1"
                     /translation="MVEALVHITTTVISGCIVALFTHWLRTRNNKKK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            15554..15775
                     /locus_tag="NT398_RS14630"
                     /old_locus_tag="NT398_14635"
     CDS             15554..15775
                     /locus_tag="NT398_RS14630"
                     /old_locus_tag="NT398_14635"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002504105.1"
                     /translation="MAKYWKENQEGLLNDGEALTILMMLYNEHPYVVQLPCLNKQLQDD
                     NRYAQPTYTIYSTTKNRKENKRRIKNSI"
                     /name="hypothetical protein"
     gene            complement(15898..16047)
                     /locus_tag="NT398_RS14635"
                     /old_locus_tag="NT398_14640"
     CDS             complement(15898..16047)
                     /locus_tag="NT398_RS14635"
                     /old_locus_tag="NT398_14640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019469204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="WP_002504104.1"
                     /translation="MKTLNEKQLKDINGGKGIVGEVTGEVTSIGNAISNGWHDLKQSVA
                     DTTK"
                     /name="bacteriocin"
     gene            complement(16068..16211)
                     /locus_tag="NT398_RS14640"
                     /old_locus_tag="NT398_14645"
     CDS             complement(16068..16211)
                     /locus_tag="NT398_RS14640"
                     /old_locus_tag="NT398_14645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019469205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002504103.1"
                     /translation="METLNEKQLKDINGGRETGCSGDFVEDGIMCNIGQGIGKAINKVR
                     GK"
                     /name="hypothetical protein"
     gene            complement(16368..18524)
                     /locus_tag="NT398_RS14645"
                     /old_locus_tag="NT398_14650"
     CDS             complement(16368..18524)
                     /locus_tag="NT398_RS14645"
                     /old_locus_tag="NT398_14650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440725.1"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]; GO:0008233 - peptidase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_002504102.1"
                     /translation="MAIKFIRQYDEKDCGPTCLAMISQFYGKRVSIPRLREYAKTDKLG
                     TNLYGLVQAGKKIGIELTGVKADSFDDLKQAQLPVMVHIINQQGYDHYIIIEKIKNNTL
                     YIVDPAKGKYKLSSTEFGKYWTNIAVLIDKTDDFTTDNESPSYLNIFIDIFKNNYGKLL
                     FIAFISLFINIVGIVGALYFKLLTDHIIPSNVLKNLHIISFGILLLYIINALINYLRFQ
                     LILHLSLKIDVNLMKDYFYHVLHLPMNFFDTRKSGEILQRFMDTSKIREALSSSTVTLL
                     VDTFMIIIGAILLYMQSPLLLLITIIFIPCFIICSYTLRKPFEKYNQKVAEKDAELSSY
                     LIESFDGSNTIKSYQSEDDRFYIGTTKFNGIIENLLKLGRFSNIQLTVNNFLKLTISLV
                     ILWLGSYLVMTDSMTLGSLLAFNALTIYYLDPIERLINIQPTLQSSFVAARRIAEITDL
                     ETETELYTSKQPYTFKNNIRIENVNFQYGFRSVVLKDINLNIKKGQKVAIVGESGSGKS
                     TIGKLLNRYYTASEGNIMIDNYIIDDIDLSDLRKNIGYVSQNTFLFADTIKNNLLHGSN
                     KYKSDEDIVKACQLAESLDFIQKFPDQFNTMLEKEGANLSGGQGQRLSLARTFLKDPDI
                     YIFDEATSALDSLTENKIMEHIDLLTQHGKTVIIISHKLSTIKNADNIYVLNEGQIAEN
                     GTHDELIHLNGIYKNLWQLQMKID"
                     /name="peptidase domain-containing ABC transporter"
     gene            18752..19360
                     /locus_tag="NT398_RS14650"
                     /old_locus_tag="NT398_14655"
     CDS             18752..19360
                     /locus_tag="NT398_RS14650"
                     /old_locus_tag="NT398_14655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583537.1"
                     /translation="MIIGYARVSSVDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEVINTVNYLKDKEVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIVQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKNGKGLS"
                     /name="recombinase family protein"
     gene            complement(19612..20286)
                     /locus_tag="NT398_RS14655"
                     /old_locus_tag="NT398_14660"
     CDS             complement(19612..20286)
                     /locus_tag="NT398_RS14655"
                     /old_locus_tag="NT398_14660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_010775116.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYRIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQSPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            <20344..20874
                     /locus_tag="NT398_RS14660"
                     /old_locus_tag="NT398_14665"
                     /pseudo=""
     CDS             <20344..20874
                     /locus_tag="NT398_RS14660"
                     /old_locus_tag="NT398_14665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /name="IS256-like element IS256 family transposase"
     gene            20931..21323
                     /locus_tag="NT398_RS14665"
                     /old_locus_tag="NT398_14670"
     CDS             20931..21323
                     /locus_tag="NT398_RS14665"
                     /old_locus_tag="NT398_14670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_000393259.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCYT
                     LLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRACH
                     VYEKLGGKNDYKDEIVYVYDYEKGDK"
                     /name="GNAT family N-acetyltransferase"
     gene            21324..22763
                     /gene="aph(2'')-Ia"
                     /locus_tag="NT398_RS14670"
                     /old_locus_tag="NT398_14675"
     CDS             21324..22763
                     /gene="aph(2'')-Ia"
                     /locus_tag="NT398_RS14670"
                     /old_locus_tag="NT398_14675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="WP_001028144.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLES
                     LKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFIGE
                     PNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLPEHE
                     LHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNE
                     YIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTF
                     LTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIY
                     NDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGI
                     IDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIK
                     NIKQEFIENGRKEIYKRTYKD"
                     /name="aph(2'')-Ia"
     gene            complement(22930..23604)
                     /locus_tag="NT398_RS14675"
                     /old_locus_tag="NT398_14680"
     CDS             complement(22930..23604)
                     /locus_tag="NT398_RS14675"
                     /old_locus_tag="NT398_14680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_010775116.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYRIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQSPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(23661..24227)
                     /gene="qacR"
                     /locus_tag="NT398_RS14680"
                     /old_locus_tag="NT398_14685"
     ARG             complement(23665..24227)
                     /name="qacR"
                     /gene="qacR"
                     /gene_name="multidrug-binding transcriptional regulator
                     QacR"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="99.47"
                     /coverage="100.0"
     gene            24405..25949
                     /gene="qac"
                     /locus_tag="NT398_RS14685"
                     /old_locus_tag="NT398_14690"
     CDS             24405..25949
                     /gene="qac"
                     /locus_tag="NT398_RS14685"
                     /old_locus_tag="NT398_14690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QacA/B family quaternary ammonium compound efflux
                     MFS transporter"
                     /protein_id="WP_058342586.1"
                     /translation="MISFFTKTTDMMTSKKRWTALVILAVSLFVVTMDMTILIMALPEL
                     VRELEPSGTQQLWIVDIYSLVLAGFIIPLSAFADKWGRKKALLTGFALFGLVSLAIFFA
                     ESAEFVIAIRFLLGIAGALIMPTTLSMIRVIFENPKERATALAVWSIASSIGAVFGPII
                     GGALLEQFSWHSAFLINVPFAIIAVVAGLFLLPESKLSKEKSHSWDIPSTILSIAGMIG
                     LVWSIKEFSKEGLADIIPWVVIVLAITMIVIFVKRNLSSSDPMLDVRLFKKRSFSAGTI
                     AAFMTMFAMASVLLLASQWLQVVEELSPFKAGLYLLPMAIGDMVFAPIAPGLAARFGPK
                     IVLPSGIGIAAIGMFIMYFFGHPLSYSTMALALILVGAGMASLAVASALIMLETPTSKA
                     GNAAAVEESMYDLGNVFGVAVLGSLSSMLYRVFLDISSFSSKGIVGDLAHVAEESVVGA
                     VEVAKATGIKQLANEAVTSFNDAFVATALVGGIIMIIISIVVYLLIPKSLDITKQK"
                     /name="qac"
     gene            26154..26714
                     /locus_tag="NT398_RS14690"
                     /old_locus_tag="NT398_14695"
     CDS             26154..26714
                     /locus_tag="NT398_RS14690"
                     /old_locus_tag="NT398_14695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_284592544.1"
                     /translation="MNRADIFKIFDVELNITIFLGALVATFIYFISYMNNVNELITLCL
                     TLAFPAYLLKISRSFEVILLEEKIKNSKIKICDKDRIEREILVKKNLIDELLFPNRVIK
                     KYTLTILIYSIGIIILLLLCNMLSYGIGENVNFIWRLLACYVTSVTVIIVALIIMIMMF
                     DLIIGLLLNFQIFLKNKKYDDFL"
                     /name="hypothetical protein"
     gene            <26778..26912
                     /locus_tag="NT398_RS14895"
                     /pseudo=""
     CDS             <26778..26912
                     /locus_tag="NT398_RS14895"
                     /inference="COORDINATES: protein motif:HMM:NF019887.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /name="HAD hydrolase family protein"
     gene            complement(27037..27804)
                     /locus_tag="NT398_RS14695"
                     /old_locus_tag="NT398_14700"
     CDS             complement(27037..27804)
                     /locus_tag="NT398_RS14695"
                     /old_locus_tag="NT398_14700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002489261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_001829872.1"
                     /translation="MRTIKMVADELGVTKQTIVNNAKSLNITFEKENGINYIDDNDYLK
                     IIEKITKKESTIQNKESVKKELFGENTAKSEKNIYNNSNSSETLKTKVNELEKQIEIFE
                     TRAKNDEKYIENLTKQLDQQNSNVNTLNKLLENQQILALESNKKIQKLESQLEEERQLN
                     YSFDTATNNRQNINPQEATFTEESQNINQQQTKRQPTEVNYKDIAEEKKNDSTDEGELT
                     KEDKFVEETKNDPDDNREVEPPKKGFWSRFFGN"
                     /name="DUF536 domain-containing protein"
     ARG             24406..25946
                     /name="qacA"
                     /gene="qacA"
                     /gene_name="quaternary ammonium compound efflux MFS
                     transporter QacA"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="99.81"
                     /coverage="100.0"
     ARG             21325..22760
                     /name="aac(6')-Ie/aph(2'')-Ia"
                     /gene="aac(6')-Ie/aph(2'')-Ia"
                     /gene_name="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(5675..6159)
                     /name="lnuA"
                     /gene="lnuA"
                     /gene_name="lincosamide nucleotidyltransferase (LNU)"
                     /tool="rgi"
                     /drug_class="lincosamide antibiotic"
                     /identity="97.52"
                     /coverage="100.0"
     ARG             7268..8037
                     /name="ANT(4')-Ia"
                     /gene="ANT(4')-Ia"
                     /gene_name="ANT(4')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.21"
                     /coverage="101.19"
     ARG             21325..22763
                     /name="AAC(6')-Ie-APH(2'')-Ia bifunctional protein"
                     /gene="AAC(6')-Ie-APH(2'')-Ia bifunctional protein"
                     /gene_name="aminoglycoside bifunctional resistance protein"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     BGC             11368..23527
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          2..936
                     /name="rep_cluster_1215"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.145"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          3978..4821
                     /name="rep_cluster_1281"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="86.203"
                     /coverage="91.0"
                     /evalue="0.0"
     Typing          9051..9951
                     /name="rep_cluster_1118"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="95.0"
                     /evalue="0.0"
     Typing          11682..12859
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="95.0"
                     /evalue="0.0"
ORIGIN
        1 atgcccaatt ttgaaaaata caatttatca caagtaaaaa ctgaaaggtt ttatcaacta
       61 cctaaatatt tattcgaaga tgcatatttt aaaaaaatgt cggcggaagc caaaattatg
      121 tatgcgttat taaaagatcg ctttgaatta tccatccaaa atgaatgggt agataaaaat
      181 aataacattt actttatttt cagtaataaa catttgtgcg aatacttagg ttatgcagaa
      241 caaaaaatta taaaattaaa aaaagagtta ataagtttta atttattaac tcaagaacgt
      301 gttggcctta ataaaccaaa tagattatat ttattaaaac ctaattatga cattaaagcc
      361 agtcatagca aggaacttcc aaattcacag ttccagaaca atgaatttgg aagttctaga
      421 actgtgaatt taagtggtca agaacttcca aattcacagt ctaatgatac tgagaataat
      481 gatactgatt atattaaaac tgagagtaat gatacgaatg atttgaatga taataagcta
      541 acttttccta gtaatcatac aaatcattca aatcacaaca attcaaactt taataatgaa
      601 gctttaaaat tccaattact cgaagaacta cctcaaagta ttcaaaggta tttaagtaac
      661 ttttctgtaa atgaaattaa aatcatcaaa cctgtattat taaaagccaa gacgtccttt
      721 aataattcta ttgatacata ttacttatta gaagatatgg aaatagaaat acttcatgtt
      781 cttaaacgtt tcaaagctat gcttattcaa aaaaatgaaa ccgttgaagc catgcaaggg
      841 tacttaatga aatcccttaa gtctgaattc gctgaaatgc atacgcttaa taaacgacgt
      901 gatcatttac caatcacttc tttatttaat caataatgat tcaattagag agcatcttta
      961 aatagatgtt ctcttttttt atttacaagt ggttgctaag gcaaccacct agatcaaacg
     1021 aaaggtaagg gaggggataa caaaataaga tcaacacaat atcacaatat agcatgctgc
     1081 tattaaagaa aggaggaaga attatgagta ctaagaaaaa gattaaagtt actttggcaa
     1141 tgattaatgt tcttttaact gcagtcgaac tttatcttca atggcaattg agtaaatctg
     1201 aaaatgaact gtagttaaac aagtaggtag gactaaaacg tttctgtttt agtcctattt
     1261 tttctataaa tggttattat tcatttgaaa atggctcaaa catgtcgcat aagatgaaaa
     1321 ataaaatgat catttaacgt tgttttaact ttaaaaatta taaaaatact aaccgttttt
     1381 atattcttta gcaatctttc ttagttataa aagtaactta ataaaatcgt ttttgtcatt
     1441 tactttgtta atgatcggaa agaaaagatt gattttatca ttccaaaaaa tcaaaattca
     1501 gattcaattg atatacatca taaacaaaaa gtaagtcgtt aatgttcaag acataagtcg
     1561 aatgtaattt taaatttgat tttttctatc ccaaactgag taaagatatt tacttagttt
     1621 tctttttttt tatctccaat tattttacta acaatgctta ttttgaaaat aaaaataagc
     1681 acttaaagta aaaagtgaac aagagaatag ccacttttgt cttaaagcac gttttgtttt
     1741 tggaaatatt acaaatataa taggattttc aaatagtatt tgacatgagc ataaggaaat
     1801 ccagtaccac ctttggtggt attcagcata gctgaaggat tgtcttaccg ttcgctttgc
     1861 ttacttgctc tttgaaattc actacaagtg ttgatataac aacatttata gttaatatta
     1921 aataaaaatt aatcgacatt ataaacctta atattgcata ctatttacaa ttgttacaag
     1981 accactttaa attgtctgaa tactattgtt tttattgatt tcataggctt cagtcgtcgt
     2041 caatcctata aataggattg atttttttat ccaaatccta ttaatcctat tacttttagt
     2101 attaatatca aaaataaaat cactcaaaag taatctaagt aattcattca tttgttttac
     2161 tttttgaaat tgactaaata ctttttgctc aatatcgtat tcaataatga tcttattatt
     2221 tatttttaag ttcaaaaaag aagggaaaga ataaaacaat ttctatactt ttctatgctc
     2281 gattttatta aaaagtgacc cgaaataaag atcactttat ctttttatta aatagaaaat
     2341 taaaaaaacg gaaaaatata taataagatt catcgaatga ttactcaaat ttttgtttgt
     2401 gaaatacatt tatatttatt tgattctcat ttgcgtttta agagctaact taaaatttca
     2461 gaagctctta ctcacttttt ggatgataaa agtgaaaata ataccaaaaa atcaagaaaa
     2521 gatattttaa ttataacgta gcatttatga cgaaaaaatt tattgttcgt tgagaagaac
     2581 tcttaactaa acttatagac gaatgtcggt atagcgtgag ctattaagcc gaccattcga
     2641 caattttagg gagcaattgt gataaagtat taatgtttta aacctgttac atcattgatt
     2701 tcgttgggat gtaacaggtt tgtttctttt aatttggatt tgttgtgaga ttataaattt
     2761 ataaaaaaca aggagaagct tatgatatcg aataaattaa aatctgcgag attagcaaag
     2821 gaattaacgc aatctgaggt agctaaaaaa ttatacgtta ctagacaaac tgtttctcga
     2881 tgggagcaag gtaaaacgtt gcctaatatt tatgtaattc aagaattaag cgatctttat
     2941 gatatttctt tagatgaatt agtagtaaat acagcattag aaaataagga ggctaaaagt
     3001 atgaaaaatg taaatccttt tgctttattt ggagcgatat tatttaatgt gtttttattt
     3061 tctttaatag ttatattttt tggtggcttt ttgttattat ctttattcat ttctttagct
     3121 atgttattta gtcctttgat tttagcaatc tttgttttaa cgggtgtaca agagtttaat
     3181 gtaattcaac tagttatgac tgttattttc gttgttattg gtttgttatc aattccttta
     3241 ttgaaaaaag tcagtgtatt tttatttaaa tttttcaaac gatatttgaa atttaatcat
     3301 aaagcaattt tttattgaat ttagaaacga gtttctttat aaaagtaagc aaagatataa
     3361 tataaaatga cttatcggaa gtgaatatgc ttatgtattt acaaatgata taataataga
     3421 gtcgcctatc tctcaggcgt caatttgacg tagagaggag gtgcatacgc gatgtctgaa
     3481 atctttgtga acatcatgac cacagcagca agtggttgtc tcgttgcgct atttgcgcat
     3541 tggctacgca agcgtaatga cgaataggcg actagtcaca ccaaaaaatc cccttactac
     3601 ggccatagta aggggatttg gtgcatacat gcctgataat ctttgttaat tacattgtaa
     3661 cactataatt ggtaggaatg caaagttcat aaagtttgag cgtaaatatt ataattacgg
     3721 agttatttta tttatatctg tagtatatat aaataggaat agggttaatg atatttataa
     3781 aacatgcatt tttaattgat gttttaaggt tctgttgcaa acttgaaaat catataatat
     3841 agatacaaag aaatgaaaaa taataaaatc caaccgaata atctgttgat ataatagtat
     3901 ataatttact gcttttgcat aactttgtat attaatttaa ctttgcaaca gaaccaaacg
     3961 acatattggg gaaaatcaaa tggatttagt tgagaattgt aatacatttt tgtcttttgt
     4021 gacgaataga agaatggaca aaaagaaatt atataaatct aatccatgta aaaatcgttt
     4081 ttgtccgatg tgtgcatggc gaaaggcgag aaaagatgca ttaggtttgt cattgatgat
     4141 gcagcatatt aagcaagcag aagataagca attcatcttt ttaacactta caacgccaaa
     4201 tgtaacaagt gaacatttgg aaagtgaaat aaaacattat aatcaatcat tcagacgatt
     4261 aagtaatcgt aaacatttta agtctatagc taaaggttat gttagaaaat tagaaattac
     4321 ttataacaaa aagtgtgatg attataaccc acattttcat gtattgattg ccgttaataa
     4381 atcatatttt aaagatacta aagcttatat tactcaaaaa gaatggctag aaatgtggcg
     4441 tgatgtcaca ggaaattctg aaattacaca agtacatata caaaaagtta agcaaaataa
     4501 taataaagaa ctttacgaaa tggctaaata ttctggtaag gataatgact atttaattaa
     4561 tcaaaaagtg ttcgacgcat tttataaagc gttaaaagga aaacaagttc ttgtttattc
     4621 tggactgttt aaagacgcaa gaaagaaatt aaaaaatgga gaattagatt acttaaaaga
     4681 agttgatccg accgaatata tttatcaaat tttttatact tggaataaaa aagagtattt
     4741 agcgagtgaa atttttgatt taacagaaag tgaaaaacaa gaaattaatc atcaaatgat
     4801 tgatgaaatt gaagaagaaa aataaaaata aattttctta aacgttagca aaaagctagc
     4861 gtttttttgt tgaaaatacg ttaaaaatgg ctgggtacaa actgggtaca gacacaatat
     4921 ataggggtac aaccggggta caatcgcaat ttgtaggggt acaatcgggg tacaaaataa
     4981 atttctaggc acctatgaaa aatctctgta tcccttgaaa tgtctggctt cgccagaccc
     5041 acctttttaa aaggtggcaa atttccctta tgctcttaac tcttgatttg ggttcaattc
     5101 aaaatttggt attttttgaa agaaattgcc cctgcaggaa ctaaaaaagt tgatgaattt
     5161 ttgagccatt ttatgccaat ttttaatttg catataactg ggcacagtgt ctaaaaaaac
     5221 ggcactggtt ttgctcaaat ttttgtttgt gaaattaaaa tatatttatt tggctctcat
     5281 ttgcgtttta agagccaata taagtttttg ggtataaaac tatataaata actctaattt
     5341 ttcaaaatac cgccttaaaa ttaaaaataa aggtattctg atttgtaata aattaaaata
     5401 taaaaaaaga gccaccattt aaaatttagg cagctcttac tcactttttg gatgataaaa
     5461 gtggaaaatt aattcgagaa aaaacagaaa ggatatttta attataacac ggcatttatg
     5521 ccgagaaaat ttattgatgt tgagaagaac ccttaactaa acttgtagac gaatgtcggt
     5581 atagcgtgag ctattaaacc gaccattcga caagttttgg gattgttaag ggttccgagg
     5641 ctcaacgtca ataaagcaat tggaataaag caattatgtt attgatttta aattttttat
     5701 atcaaaatgg tctttttctg ttaaatcata accagaatga aaaagaagtt gagcttcttt
     5761 tgaaatacat ggtatttttc gacctttgta attagtttct gaaaaccagt cattttggaa
     5821 aacataatta ccaccttctg ggtttgcttg ggtaattgat ccatcatcat ttagatttat
     5881 aggatgaata tctaaatacc catattcttc atgcttaagt tccatacgtg aaggcatcca
     5941 atcaacttct attttgtatc ctatatcttc taatttttgt ataacttttt gagtgtgttg
     6001 agcgtcaaaa tctatatcta tatctctgtg ttctctttgt tgttttccag ttaatacatc
     6061 taccccccag ccaccatcta accaataagt tactttcatg tgttcaaata aatctaaaat
     6121 ataaaataaa tctttttctg ttacattatt atttttcatt ttatccctcc taacttggga
     6181 atttgaaaca agttgaaaac gagtttcttc ttgtcttgat aataagggta actattacaa
     6241 gctgtgatag ttacccttat tccattgata tgactggttt taagcacaaa aaaagttgcc
     6301 ttttccagca tactattgta tcgttttagg tgtctaagct aaacgaaaaa tagaaaggag
     6361 aaaaagcaac gtcttttcgt atttcaaaca aagttgtttt atgtgaatta tatgaaaaag
     6421 tatactgaga aaaaacaaag aaatcaagta tttcaaaact ttattaaacg acaggttctg
     6481 ttgcaaactt gaaaatcata taatatagat acaaagaaat gaaaaataat aaaatccaac
     6541 cgaataatct gttgatataa tagtatataa tttactgctt ttgcataact ttgtatatta
     6601 atttaacttt gcaacagaac caataataaa gataattctt ataatcagca catgcatgta
     6661 ttggtatgtg tggaaccaac ttattttaag aatacagaaa actacgtgaa tcaaaaacaa
     6721 tggattcaat tttggaaaaa ggcaatgaaa ttagactatg atccaaatgt aaaagttcaa
     6781 atgattcgac cgaaaaataa atataaatcg gatatacaat cggcaattga cgaaactgca
     6841 aaatatcctg taaaggatac ggattttatg accgatgatg aagaaaagaa tttgaaacgt
     6901 ttgtctgatt tggaggaagg tttacaccgt aaaaggttaa tctcctatgg tggtttgtta
     6961 aaagaaatac ataaaaaatt aaaccttgat gacacagaag aaggcgattt gattcataca
     7021 gatgatgacg aaaaagccga tgaagatgga ttttctatta ttgcaatgtg gaattgggaa
     7081 cggaaaaatt attttattaa agagtagttc aacaaacggg ccagtttgtt gaagattaga
     7141 tgctataatt gttattaaaa ggattgaagg atgcttagga agacgagtta ttaatagctg
     7201 aataagaacg gtgctctcca aatattctta tttagaaaag caaatctaaa attatctgaa
     7261 aagggaatga gaatagtgaa tggaccaata ataatgacta gagaagaaag aatgaagatt
     7321 gttcatgaaa ttaaggaacg aatattggat aaatatgggg atgatgttaa ggctattggt
     7381 gtttatggct ctcttggtcg tcagactgat gggccctatt cggatattga gatgatgtgt
     7441 gtcatgtcaa cagaggaagc agagttcagc catgaatgga caaccggtga gtggaaggtg
     7501 gaagtgaatt ttgatagcga agagattcta ctagattatg catctcaggt ggaatcagat
     7561 tggccgctta cacatggtca atttttctct attttgccga tttatgattc aggtggatac
     7621 ttagagaaag tgtatcaaac tgctaaatcg gtagaagccc aaacgttcca cgatgcgatt
     7681 tgtgccctta tcgtagaaga gctgtttgaa tatgcaggca aatggcgtaa tattcgtgtg
     7741 caaggaccga caacatttct accatccttg actgtacagg tagcaatggc aggtgccatg
     7801 ttgattggtc tgcatcatcg catctgttat acgacgagcg cttcggtctt aactgaagca
     7861 gttaagcaat cagatcttcc ttcaggttat gaccatctgt gccagttcgt aatgtctggt
     7921 caactttccg actctgagaa acttctggaa tcgctagaga atttctggaa tgggattcag
     7981 gagtggacag aacgacacgg atatatagtg gatgtgtcaa aacgcatacc attttgaacg
     8041 atgacctcta ataattgtta atcatgttgg ttacgtattt attaacttct cctagtatta
     8101 gtaattatca tggctgtcat ggcgcattaa cggaataaag ggtgtgctta aatcgggcca
     8161 ttttgcgtaa taagaaaaag gattaattat gagcgaattg aattaataat aaggtaatag
     8221 atttacatta gaaaatgaaa ggggatttta tgcgtgagaa ggttctgttg caaagttgaa
     8281 tttataatat aattttaaca aaaaggagtc ttctgtatga accatttcag atataaacaa
     8341 tttaacaagg atgttatcac tgtagccgtt ggctactatc taagatatgc attgagctat
     8401 cgtgatatat ctgaaatatt aagagaacgt ggtgtaaacg ttcatcattc aacgatctac
     8461 cgttgggttc aagaatatgc cccaatttta tatcaaattt ggaagaaaaa gcataaaaaa
     8521 gcttattaca aatggcgtat tgatgagacg tatatcaaaa taaaaggaaa atggagctat
     8581 ttatatcgtg ccattgatac agagggacat acattagata tttggttgcg taagcaacga
     8641 gataatcatt cagcatatgc gtttatcaaa cgtctcatta aacaatttgg taagcctcaa
     8701 aaggtagtta cagatcaggc accttcaacg aaggcagcaa tggctaaaat aattaaagct
     8761 tttaaactta aacctgactg tcattgtaca tcgaaatatc tgaataacct cattgagcaa
     8821 gatcaccgtc atattaaagt aagaaagaca agatatcaaa gtatcaatac ggcaaagaat
     8881 actttaaaag gtattgaatg tatttacgct ctatataaaa agaaccgtag gtctcttcag
     8941 atctacggat tttccccatg ccacgaaatt agcatcatgc tagcaagtta aacgaacact
     9001 gacatgatat attagtgatt agctatattt tttactttgc aacagaacca tcacgattta
     9061 gacaattttt ctaaaaccgg ctactctaat agccggttgg acgcacatac tgtgtgcata
     9121 tctgatccaa aattaagttt tgatgcaatg acgatcgttg gaaatctcaa ccgagacaac
     9181 gctcaagccc tttctaaatt tatgagtgta gagccccaaa taagactttg ggatattctt
     9241 caaacaaagt ttaaagctaa agcacttcaa gaaaaagttt atattgaata tgacaaagtg
     9301 aaagcagata gttgggatag acgtaatatg cgtattgaat ttaatccaaa caaacttaca
     9361 cgagatgaaa tgatttggtt aaaacaaaat ataataagct acatggaaga tgacggtttt
     9421 acaagattag atttagcctt tgattttgaa gatgatttga gtgactacta tgcaatgtct
     9481 gataaagcag ttaagaaaac tattttttat ggtcgtaatg gtaagccaga aacaaaatat
     9541 tttggcgtga gagatagtaa tagatttatt agaatttata ataaaaagca agaacgtaaa
     9601 gataatgcag atgctgaagt tatgtctgaa catttatggc gtgtagaaat cgaacttaaa
     9661 agagatatgg tggattactg gaatgattgc tttagtgatt tacatatctt gcaaccagat
     9721 tggaaaacta tccaacgcac tgcggataga gcaatagttt ttatgttatt gagtgatgaa
     9781 gaagaatggg gaaagcttca cagaaattct agaacaaaat ataagaattt gataaaagaa
     9841 atttcgccag tcgatttaac ggacttaatg aaatcgactt taaaagcgaa cgaaaaacaa
     9901 ttgcaaaaac aaatcgattt ttggcaacat gaatttaaat tttggaaata gtgtacatat
     9961 taatattact gaacaaaaat gatatattta aactattcta atttaggagg atttttttat
    10021 gaagtgtcta tttaaaaatt tggggaattt atatgaggtg aaagaataat ttacccctat
    10081 aaactttagt cacctcaagt aaagaggtaa aattgtttag tttatataaa aaatttaaag
    10141 gtttgtttta tagcgtttta ttttggcttt gtattctttc attttttagt gtattaaatg
    10201 aaatggtttt aaatgtttct ttacctgata ttgcaaatca ttttaatact actcctggaa
    10261 ttacaaactg ggtaaacact gcatatatgt taactttttc gataggaaca gcagtatatg
    10321 gaaaattatc tgattatata aatataaaaa aattgttaat tattggtatt agtttgagct
    10381 gtcttggttc attgattgct tttattggtc acaatcactt ttttattttg atttttggta
    10441 ggttagtaca aggagtagga tctgctgcat tcccttcact gattatggtg gttgtagcta
    10501 gaaatattac aagaaaaaaa caaggcaaag cctttggttt tataggatca attgtagctt
    10561 taggtgaagg gttaggtcct tcaatagggg gaataatagc acattatatt cattggtctt
    10621 acctacttat acttcctatg attacaatag taactatacc ttttcttatt aaagtaatgg
    10681 tacctggtaa atcaacaaaa aatacattag atatcgtagg tattgtttta atgtctataa
    10741 gtattatatg ttttatgtta tttacgacaa attataattg gactttttta atactcttca
    10801 caatcttttt tgtgattttt attaaacata tttcaagagt ttctaaccct tttattaatc
    10861 ctaaactagg gaaaaacatt ccgtttatgc ttggtttgtt ttctggtggg ctaatatttt
    10921 ctatagtagc tggttttata tcaatggtgc cttatatgat gaaaactatt tatcatgtaa
    10981 atgtagcgac aataggtaat agtgttattt ttcctggaac catgagtgtt attgtttttg
    11041 gttattttgg tggtttttta gtggatagaa aaggatcatt atttgttttt attttaggat
    11101 cattgtctat ctctataagt tttttaacta ttgcattttt tgttgagttt agtatgtggt
    11161 tgactacttt tatgtttata tttgttatgg gcggattatc ttttactaaa acagttatat
    11221 caaaaatagt atcaagtagt ctttctgaag aagaagttgc ttctggaatg agtttgctaa
    11281 atttcacaag ttttttatca gagggaacag gtatagcaat tgtaggaggt ttattgtcac
    11341 tacaattgat taatcgtaaa ctagttctgg aatttataaa ttattcttct ggagtgtata
    11401 gtaatattct tgtagccatg gctatcctta ttattttatg ttgtcttttg acgattattg
    11461 tatttaaacg ttctgaaaag cagtttgaat agttatatta tattttggtt tagaactatg
    11521 agtggctagc attttgccac tcattttttg cgttagcaaa aacaggttta agcctcgcag
    11581 agcacacgta ttaacgactt attaaaaata agtctagtgt gttattagac ttaaactatt
    11641 aaatacacat gaaacctttg tgcttaggag tgatttttat atgtcttatt ccattgttag
    11701 agtttcaaaa gttaaatctg gaacaaatac aacgggcata caaaaacatg ttcaaagaga
    11761 aaataataat tatgaaaatg aagatataga ccatagtaaa acttacttaa attatgattt
    11821 ggtaaatgct aataaacaga attttaataa cttgattgat gaaaaaatcg aacagaatta
    11881 tacaggcaaa agaaaaatta gaacagacgc gattaaacac attgatggtt taattacatc
    11941 agacaatgat ttctttgata atcaaacgcc agaagataca aagcagtttt ttgaatatgc
    12001 taaagagttt ttagaacaag aatacggtaa agataattta ttatatgcaa cagttcacat
    12061 ggacgaaaaa acaccacata tgcattatgg cgttgttcca ataactgatg atggtcgttt
    12121 aagtgctaaa gaagttgtag gtaataaaaa agctttaaca gcgtttcaag atagatttaa
    12181 tgagcatgtt aaacaacgag gatatgattt agaacgtggg caatcaagac aagtaacaaa
    12241 tgctaaacat gagcaaataa gtcagtataa acaaaaaaca gaatatcata agcaagaata
    12301 tgaacgtgag agccaaaaaa cagaccatat aaagcaaaag aacgataaat taatgcaaga
    12361 gtaccaaaaa tcgttaaata cgcttaaaaa gcctataaat gttccgtatg agcaagaaac
    12421 tgaaaaagta ggtggtttat ttagcaaaga aatacaagaa actggaaatg ttgtaataag
    12481 ccaaaaagat ttcaatgaat ttcagaaaca gataaaagct gctcaagata tttcggaaga
    12541 ttacgagtat ataaagtctg gtagagcctt agatgataaa gataaggaaa tacgagagaa
    12601 agatgattta ttaaataaag cagttgagcg tattgaaaac gcagacgata attttaacca
    12661 actttacgaa aatgcaaagc cacttaaaga gaatatagaa atagcgttaa agcttttaaa
    12721 aatcttacta aaagagttag aacgagtttt aggaagaaat acctttgcgg aaagagttaa
    12781 taagttaaca gaagatgaac caaaactaaa tggtttagca ggaaacttag ataaaaaaat
    12841 gaatccagaa ttatattcag aacaggaaca gcaacaagaa ggttctgttg caaagttgaa
    12901 tttataatat aattttaaca aaaaggagtc ttctgtatga actatttcag atataaacaa
    12961 tttaacaagg atgttatcac tgtagccgtt ggctactatc taagatatgc attgagctat
    13021 cgtgatatat ctgaaatatt aagagaacgt ggtgtaaacg ttcatcattc aacgatctac
    13081 cgttgggttc aagaatatgc cccaatttta tatcaaattt ggaagaaaaa gcataaaaaa
    13141 gcttattaca aatggcgtat tgatgagacg tatatcaaaa taaaaggaaa atggagctat
    13201 ttatatcgtg ccattgatac agagggacat acattagata tttggttgcg taagcaacga
    13261 gataatcatt cagcatatgc gtttatcaaa cgtctcatta aacaatttgg taagcctcaa
    13321 aaggtagtta cagatcaggc accttcaacg aaggcagcaa tggctaaaat aattaaagct
    13381 tttaaactta aacctgactg tcattgtaca tcgaaatatc tgaataacct cattgagcaa
    13441 gatcaccgtc atattaaagt aagaaagaca agatatcaaa gtatcaatac ggcaaagaat
    13501 actttaaaag gtattgaatg tatttacgct ctatataaaa agaaccgtag gtctcttcag
    13561 atctacggat tttccccatg ccacgaaatt agcatcatgc tagcaagtta aacgaacact
    13621 gacatgatat attagtgatt agctatattt tttactttgc aacagaacca aaagtatttt
    13681 aattataaca cggcatttat gccgagaaaa tttattgtgc gttgagaaga acccttaact
    13741 aaacttggag acgaatgtcg gcatagcgtg agctattaag ccgaccattc gacaagtttt
    13801 gggattgtta agggttccga ggctcaacgt caataaagca attggaataa agcatctatg
    13861 attatttgaa aacataagtt ataatacatt caaaaatatt tttgaatgag gtgtaattat
    13921 gattcagact attgtaactg ctgctattct ttatattgcg acagcagtag atttattagt
    13981 gattttatta atattttttg ctagagcaaa gactaagaaa gaatatcgag atatttatat
    14041 tggtcaatat gtaggatctg tggcattgat tgtcgtaagt ttattctttg cctttgtctt
    14101 aaattatgtt cctgaaaaat ggatattagg attattaggg ttaataccga tttatttagg
    14161 aattaaagta gctatttatg atgattgtga aggagaaaag agagctaaaa aagaattgaa
    14221 tgaaaaagga ttgtctaaat tagttggtac ggttgcaatt gttacgatag caagttgtgg
    14281 tgctgataat attggtttat ttgttccgta ttttgtgaca ttaagtgtta ctaatttatt
    14341 aattactctg tttgtctttt taattttaat tttcttcttg gtatttactg cacaaaaatt
    14401 atctaatatt ccaggagttg gagaaattgt tgagaaattt agtcgttgga ttatggctgt
    14461 tatttatata gctttaggtt tatttattat tattgaaaat gatactattc aaacaatttt
    14521 aggatttata ttttaattta gggtgcgatt ttatatgagt tatgaaaatg cttgtgatgt
    14581 gatctgtgta catgaggata aagttaacaa tgctttaagt tttttagaag atgataaatc
    14641 taagaaatta cttaacattt tagaaaaaat ttgtgatgag aagaaattga aaatcatatt
    14701 atctttgatt aaagaagatg agttgtgtgt ttgtgatatt tctttgatat tgaaaataag
    14761 tgttgcttca acttcacatc atttaagact tttatataaa aatgatgtac ttgattttta
    14821 taaaaaggga aagatggcat attattttat taaagacgat gaaataaaag aatttttctc
    14881 taaaaatcag gagggttttt gaaacgagtg aaacgagttt cttcttgtct tgatactata
    14941 aaaaagcaaa gatataacat aaaatgactt atcggaagtt atctattatc ccttattcag
    15001 agatgatata atatacaggt cgcctatctc tcaggcgtca atttagacgc agagaggagg
    15061 tgcatatcag atggtcgaag ctcttgttca catcacgacc acagtcatca gtggttgtat
    15121 tgttgcgtta tttacgcatt ggctacgtac acgtaacaat aagaaaaaat aggcgatatt
    15181 agccaacacc taaaaatccc ctcactattg cgagtagtga ggggattggt gcatataatg
    15241 tacgaagctc ttgttgtcta aattataaca ctggttagta gaagaatgca aaacacttat
    15301 attaaaaaat gggtatcttt gagtagtatc ataagttata gtatagaaat atttaagtgt
    15361 ttgtattcag aatttagttt tccgttaaat gatgtattgc tagaaggtac tgataaaaaa
    15421 gcgagtaaag aatatataaa caagaatcaa aaaacttttt attgtctata atcatctatt
    15481 actttctttt tactagtaac ttcgataatt gcaaacagta tcattggtta ttaaaaaaat
    15541 aaaagatgca aaaatggcta aatattggaa agaaaatcaa gagggattat taaatgatgg
    15601 ggaagcatta actatattaa tgatgttata taatgagcat ccatatgtag tacaattacc
    15661 gtgtttaaat aagcaactac aagatgacaa cagatacgct caacccacgt atactatata
    15721 ttctacaacc aaaaacagaa aagagaataa aagaagaata aaaaatagca tataacctta
    15781 ataagataat taattttgtt atattaaaat aatatataga taatttaatt atttaaagtc
    15841 gaacaattaa aaaagtctgg gttattaccc agactttttt aatttaaata atgagtccta
    15901 ttttgtagta tcagcgacag actgttttaa atcatgccaa ccatttgaaa tggcattacc
    15961 aatactagtg acttcgccag tgacttcacc aacaatccct ttaccaccat tgatatcttt
    16021 taattgtttt tcatttagtg ttttcattga aatagtcctc ctttaaatta ttttcctcgt
    16081 actttattaa ttgctttacc aataccttgt ccgatattgc acattattcc atcttctaca
    16141 aaatcaccag aacaaccagt ttcacgacca ccattgatat cttttaattg tttttcattt
    16201 agtgtttcca ttgaaatagt cctcctttaa gtaatttcat cttacatctt ataaattagc
    16261 atttgaatat aaagagaatg taaatagaca gttaagtgag cttttttttg agtttatttt
    16321 ttttattatc gaaatatatt taataaatag agtatattaa tataaaatca gtctattttc
    16381 atttgaagtt gccataaatt tttatatata ccgtttaaat gaatcaactc atcatgtgta
    16441 ccattctcag caatttgacc ctcgtttaaa acatagatat tatcagcatt ttttatagta
    16501 cttaatttat gtgaaataat aattacggtt ttaccatgtt gagttagtaa gtcaatatgc
    16561 tccataattt tgttttcagt taaactatct aaggcacttg tagcttcatc gaaaatatat
    16621 atatcaggat cttttaaaaa tgtacgtgct aaagataagc gttggccttg tccgcccgat
    16681 agattagctc cttctttttc taacatagtg ttaaactgat ctgggaattt ctgtataaaa
    16741 tctaaggatt ctgctaattg acaagcttta acgatatctt catcactttt gtatttattg
    16801 ctaccatgta aaagattgtt tttaattgta tcagcaaaaa ggaatgtgtt ttgtgaaaca
    16861 tagcctatat tcttacgtaa gtcagaaaga tcaatatcat caataatata gttatcaatc
    16921 ataatattac cttctgaagc agtgtaatag cgattgagta acttacctat agttgattta
    16981 ccactaccac tttcaccaac aatagcaacc ttttgccctt ttttaatatt taaattaata
    17041 tccttcaata ccacacttcg aaagccatac tgaaagttta cattttcaat gcgaatgttg
    17101 tttttaaaag tataaggttg tttagaagta tataattcag tttcggtctc taaatcagtt
    17161 atttcagcaa tacgacgtgc tgcaacaaat gaagattgca gtgttggttg aatatttatg
    17221 agacgttcaa taggatcaag gtaataaata gttaaggcat taaaagctaa taaactacct
    17281 aacgtcatac tatccgtcat gactaagtaa ctaccaagcc acaatataac aagactgata
    17341 gttaatttta aaaagttgtt aaccgttaat tgtatattag aaaatctacc cagttttaat
    17401 aagttttcaa taataccatt aaatttagta gtaccaatgt agaaacgatc gtcttcagat
    17461 tgataacttt taatagtatt actaccatca aaggattcta ttaaatatga actcaattca
    17521 gcatcttttt cagccacctt ttgattatat ttttcaaaag gtttacgtaa agtgtaacta
    17581 caaataataa aacaaggtat aaaaataatt gttatcagta gtaacaaagg actttgcata
    17641 taaagtaata tagcaccgat aataatcatg aaagtatcaa ctagcaacgt taccgttgaa
    17701 gatgataaag cttcacgaat tttagatgta tccatgaaac gttgtaggat ttcgccagat
    17761 ttacgtgtat caaaaaagtt catcggaaga tgtaaaacat gataaaaata atctttcatt
    17821 aaattaacat cgattttcaa acttaaatgt aagataagtt gaaaccttaa ataattaatg
    17881 agtgcattga ttatgtataa aagtaaaata ccgaagctaa taatatgtaa atttttaaga
    17941 acattggatg gaataatatg atcggttaat aatttaaaat atagagcccc gacaatacca
    18001 acaatattaa taaatagtga gataaaagca ataaataaca actttccata attattttta
    18061 aatatatcaa taaaaatatt aagatacgag ggtgattcat tgtcagtagt aaaatcatct
    18121 gttttatcaa ttaatacagc aatattagtc caatattttc caaattcagt acttgataac
    18181 ttatatttac ctttagcagg atcgacaata taaagcgtgt tattttttat tttttcaata
    18241 atgatatagt gatcataacc ttgttgatta ataatatgta ccataactgg taattgtgct
    18301 tgttttaaat catcaaagga atcagctttt acgccagtta actcaatacc aatcttttta
    18361 cctgcttgta cgagaccata taaatttgta cctaatttat ctgttttagc atattcgcgc
    18421 aaacgtggga tagatacacg cttaccataa aactgtgaaa tcatggcaag gcaagtagga
    18481 ccacaatcct tttcatcgta ttgtcttata aattttatag ccatcataat gagtcctttc
    18541 aataaaattt aactctattt taataagtat aaatagttag tattaaacat aagttaaata
    18601 atccttttga taatgttaaa agcgctaaaa agtaaaaata tttgtctata tgtctacttg
    18661 tggtacaccc taatcataca aagagagtta ttgaatttat aataacttaa acgtatgatt
    18721 agggtgtata ttaattgtgg agtgaaaatg aatgattata ggttatgcaa gagtatcttc
    18781 ggtagatcag aatttagaga gacagctaga taatttgaaa acatttggcg tagagaaaat
    18841 atttacagag aaacaatcgg gaaagtcagt agaaaataga cccgtatttc aagaagcact
    18901 taactttgtg agaatgggcg atagatttgt agtagaatcg attgatcgct taggtcgtaa
    18961 ttatgatgaa gtgattaaca cagttaatta tttaaaggat aaagaagttc aattgatgat
    19021 tactagttta cctatgatga atgaagtgat tggtaatcca ctattagata aatttatgaa
    19081 agatttaatc gttcaaatct tagcaatggt ttcagaacaa gaacgaaatg aaagtaaacg
    19141 tagacaagca caaggtattc aagttgcgaa agaaaaaggt gtgtataaag gacgcccttt
    19201 actatattca cctaatgcta aagatcctca aaaacgtatt atctaccatc gtgttgttga
    19261 aatgttagaa gaaggcaaag caattagtaa gattgcgaaa gaggttaata tcacaagaca
    19321 gacagtttat agaattaaaa atggtaaggg attatcttga taaatggatt gttaatgcaa
    19381 atgagatctt ctcacagcgt cctaaattat atgttattca tctattatga gattctaata
    19441 ataagacaag aaaagagagt gcgaattcgc actctccttt tgtgtagtac tattgaaatt
    19501 ttgtcttaaa aacgaacgta atttagaaat aatatttatt ggtatttcaa gaaggttctg
    19561 ttgcaaagta aaaaatatag ctaaccacta atttatcatg tcagtgttcg cttaacttgc
    19621 tagcatgatg ctaatttcgt ggcatggcga aaatccgtag atctgaagag acctgcggtt
    19681 ctttttatat agagcgtaaa tacattcaat accttttaaa gtattctttg ctgtattgat
    19741 actttgatac cttgtctttc ttactttaat atgacggtga tcttgctcaa tgaggttatt
    19801 cagatatttc gatgtacaat gacagtcagg tttaagttta aaagctttaa ttactttagc
    19861 cattgctacc ttcgttgaag gtgactgatc tgtaattacc ttttgaggtt taccaaattg
    19921 tttaatgaga cgtttgataa acgcatatgc tgaatgatta tctcgttgct tacgcaacca
    19981 aatatctaat gtatgtccct ctgcatcaat ggcacgatat aaatagctcc attttccttt
    20041 tattttgatg tacgtctcat caatacgcca tttgtaataa gcttttttat gctttttctt
    20101 ccaaattcga tataaaattg gggcatattc ttgaacccaa cggtagaccg ttgaatgatg
    20161 aacgtttaca ccacgttccc ttaatatttc agatatatca cgataactca atgcatatct
    20221 tagatagtag ccaacggcta cagtgataac atccttgtta aattgtttat atctgaaata
    20281 gttcatacag aagactcctt tttgttaaaa ttatactata aattcaactt tgcaacagaa
    20341 ccattttttg aatacctaaa agaacgcggt ttacaaggta cggaactcgt tatttctgat
    20401 gcgcacaaag gattagtctc tgccattaga aaatccttca ccaacgtaag ttggcaaaga
    20461 tgccaagttc acttcctaag aaatatcttt accaccattc ctaaaaaaaa ttcaaaatct
    20521 ttcagagaag ctgttaaagg aatttttaag ttcacagata ttaacttagc gcgtgaggct
    20581 aaaaatcgat tgattcatga ttatatcgat caaccaaaat attcaaaagc ttgcgcatca
    20641 ttggatgatg gattcgaaga cgcctttcaa tataccgtac aaggaaattc ccacaatcga
    20701 ctaaagagta ccaatctaat tgaacgactg aatcaagaag tacgcagaag agaaaagatt
    20761 attcgcatct tccccaatca aacatcagcc aatcgcttaa ttggagccgt tcttatggac
    20821 ctacatgatg aatggattta ttcttcaaga aaatacatca attttgataa gtagaaatgg
    20881 taaaaacatt gtatagcatt ttacacagga gtctggactt gactgagttt atggaagaag
    20941 ttttaattga tgataatatg gtttttgata ttgataattt aaaaggattt cttaatgata
    21001 ccagttcatt tgggtttata gctaaagaaa ataataaaat tataggattt gcatattgct
    21061 atacactttt aagacctgat ggaaaaacaa tgttttattt acactcaata ggaatgttac
    21121 ctaactatca agacaaaggt tatggttcaa aattattatc ttttattaag gaatattcta
    21181 aagagattgg ttgttctgaa atgtttttaa taactgataa aggtaatcct agagcttgcc
    21241 atgtatatga aaaattaggt ggtaaaaatg attataaaga tgaaatagta tatgtatatg
    21301 attatgaaaa aggtgataaa taaatgaata tagttgaaaa tgaaatatgt ataagaactt
    21361 taatagatga tgattttcct ttgatgttaa aatggttaac tgatgaaaga gtattagaat
    21421 tttatggtgg tagagataaa aaatatacat tagaatcatt aaaaaaacat tatacagagc
    21481 cttgggaaga tgaagttttt agagtaatta ttgaatataa caatgttcct attggatatg
    21541 gacaaatata taaaatgtat gatgagttat atactgatta tcattatcca aaaactgatg
    21601 agatagtcta tggtatggat caatttatag gagagccaaa ttattggagt aaaggaattg
    21661 gtacaagata tattaaattg atttttgaat ttttgaaaaa agaaagaaat gctaatgcag
    21721 ttattttaga ccctcataaa aataatccaa gagcaataag ggcataccaa aaatctggtt
    21781 ttagaattat tgaagatttg ccagaacatg aattacacga gggcaaaaaa gaagattgtt
    21841 atttaatgga atatagatat gatgataatg ccacaaatgt taaggcaatg aaatatttaa
    21901 ttgagcatta ctttgataat ttcaaagtag atagtattga aataatcggt agtggttatg
    21961 atagtgtggc atatttagtt aataatgaat acatttttaa aacaaaattt agtactaata
    22021 agaaaaaagg ttatgcaaaa gaaaaagcaa tatataattt tttaaataca aatttagaaa
    22081 ctaatgtaaa aattcctaat attgaatatt cgtatattag tgatgaatta tctatactag
    22141 gttataaaga aattaaagga acttttttaa caccagaaat ttattctact atgtcagaag
    22201 aagaacaaaa tttgttaaaa cgagatattg ccagtttttt aagacaaatg cacggtttag
    22261 attatacaga tattagtgaa tgtactattg ataataaaca aaatgtatta gaagagtata
    22321 tattgttgcg tgaaactatt tataatgatt taactgatat agaaaaagat tatatagaaa
    22381 gttttatgga aagactaaat gcaacaacag tttttgaggg taaaaagtgt ttatgccata
    22441 atgattttag ttgtaatcat ctattgttag atggcaataa tagattaact ggaataattg
    22501 attttggaga ttctggaatt atagatgaat attgtgattt tatatactta cttgaagata
    22561 gtgaagaaga aataggaaca aattttggag aagatatatt aagaatgtat ggaaatatag
    22621 atattgagaa agcaaaagaa tatcaagata tagttgaaga atattatcct attgaaacta
    22681 ttgtttatgg aattaaaaat attaaacagg aatttatcga aaatggtaga aaagaaattt
    22741 ataaaaggac ttataaagat tgattatata atatatgaaa agctattata aaagacatta
    22801 gtattaaata gtttaaaaaa atgaaaaata ataaaggaag tgagtcaagt ccagactcct
    22861 gtgtaaaatg cggttctgtt gcaaagtaaa aaatatagct aaccactaat ttatcatgtc
    22921 agtgttcgct taacttgcta gcatgatgct aatttcgtgg catggcgaaa atccgtagat
    22981 ctgaagagac ctgcggttct ttttatatag agcgtaaata cattcaatac cttttaaagt
    23041 attctttgct gtattgatac tttgatacct tgtctttctt actttaatat gacggtgatc
    23101 ttgctcaatg aggttattca gatatttcga tgtacaatga cagtcaggtt taagtttaaa
    23161 agctttaatt actttagcca ttgctacctt cgttgaaggt gactgatctg taattacctt
    23221 ttgaggttta ccaaattgtt taatgagacg tttgataaac gcatatgctg aatgattatc
    23281 tcgttgctta cgcaaccaaa tatctaatgt atgtccctct gcatcaatgg cacgatataa
    23341 atagctccat tttcctttta ttttgatgta cgtctcatca atacgccatt tgtaataagc
    23401 ttttttatgc tttttcttcc aaattcgata taaaattggg gcatattctt gaacccaacg
    23461 gtagaccgtt gaatgatgaa cgtttacacc acgttccctt aatatttcag atatatcacg
    23521 ataactcaat gcatatctta gatagtagcc aacggctaca gtgataacat ccttgttaaa
    23581 ttgtttatat ctgaaatagt tcatacagaa gactcctttt tgttaaaatt atactataaa
    23641 ttcaactttg caacagaacc ttatttacta agtccattta aaaaaatttg agagaacttg
    23701 ttcataagtt taattctttc attaatattt tgttcatgtg taaaggtaac aattccatta
    23761 acagcgtttg ctgctatttt actaacagca ttaacatcat taatacacca ttcgccattt
    23821 aaattaccct ccttaaaaat tacatgataa gcatctatat atttgttttc taatttattc
    23881 attttttcat taatgctatt agttttataa tattcagtgc aaaattcaat tattgcgttt
    23941 tgaagtggat aatagtattc ggttgttaaa gatagttcat tatataaata aaatttttct
    24001 ctattagttt tacatttgat ttgttccttt ttccactgtt cttgccattt agattcttct
    24061 atatttaaaa tttctaaaaa tagattttct tttgttttaa agtgataata aagattccct
    24121 ttactacttt ctgataattt aacaatttct ccagtagtag tggcattata tccatttttt
    24181 ataaataatt cctttgcgac acctagtatt ttatctttca agttcatcac gcctttaatg
    24241 agtattaagt actatcaatg atagcacaaa aaattcaaag aataattgta taacacaata
    24301 cagccattta aatttcgcaa gattttttgt tgtaatatgt aaaaaaatag attacaatcc
    24361 ttatagaccg atcgcacggt ctataaggat tggagggaac ttaaatgatt tcatttttta
    24421 caaaaactac tgatatgatg acatcaaaaa aaagatggac tgcactagta atattagctg
    24481 ttagtttgtt tgttgttaca atggatatga caatattaat tatggcttta ccggaattag
    24541 taagagagtt agagccttct ggtacccaac agttatggat agttgatata tactctcttg
    24601 ttttagctgg ctttataatt ccattgagtg cctttgctga taaatgggga agaaaaaaag
    24661 cattattaac tggatttgct ttatttggcc tcgtttcatt agctatattt ttcgcagaaa
    24721 gtgcagagtt cgtaatagct attcgatttt tacttggtat tgcaggtgct ttaataatgc
    24781 caactactct ttcaatgata agagtaattt ttgaaaaccc taaagaaagg gccactgcat
    24841 tagctgtatg gtcaatcgct tcatcgatag gtgctgtttt tggaccaatt atcggaggag
    24901 ctttacttga gcaattttca tggcactcgg catttttaat taatgtaccg tttgcgataa
    24961 tagcagttgt agcaggttta tttttattac cagagtctaa gttatcaaaa gaaaagtctc
    25021 actcgtggga tattccttct acaattttat caattgcagg catgattgga ctggtatgga
    25081 gtatcaaaga attttcaaaa gaaggactag cagatattat tccatgggtt gtaatagtat
    25141 tagcaattac catgatagtg atatttgtta aacgtaattt atcaagttct gatccaatgt
    25201 tagacgtaag actttttaaa aagagatcat tttcagctgg tacaattgct gcatttatga
    25261 caatgtttgc aatggcatct gttttgttat tagcttcaca atggttacag gttgtggaag
    25321 aactttctcc ttttaaagct ggcttatacc tattacctat ggcaatagga gatatggtgt
    25381 ttgcaccaat tgcacccgga ttagcggcgc gatttggacc gaaaatagtg ttaccttccg
    25441 gaattggaat tgcagccatt ggcatgttta ttatgtattt ctttggtcat ccattatcat
    25501 attctacaat ggctttagca ttaattttag ttggagctgg tatggcttca ctagcagttg
    25561 catctgctct aataatgtta gaaacaccta catcaaaagc aggtaatgca gctgctgttg
    25621 aagagtctat gtatgacctt ggaaatgttt ttggtgtagc agtacttggt agcctatctt
    25681 ctatgcttta tcgtgtattt ttagatattt catctttttc atcaaaaggt atagttggag
    25741 atttagctca tgtagctgaa gaatctgtag tgggcgctgt cgaagtagct aaagctacgg
    25801 ggataaaaca gcttgcaaac gaggctgtaa catcatttaa tgatgctttt gtagcaactg
    25861 ctttagtagg tgggattatc atgattatca tttcaatagt tgtctatttg ttaattccca
    25921 aatcacttga tataactaaa caaaaatagt actaaacata tatttttaga tattgtagat
    25981 tagtttattt ttaaaattag taatagttaa aaagtagaac cattaatttt aaatggttct
    26041 acttttttat tattaagtaa aattataaaa gacaatttct taaattaata atatgatata
    26101 cctatatcta ataatttatt agtattaata aaccttgaaa ggatgattaa ctgatgaata
    26161 gagcagatat ttttaaaata tttgatgtag aacttaatat aactatattt ttaggagcac
    26221 tagtagcaac tttcatctat tttataagtt acatgaacaa tgtaaatgaa ttaattacat
    26281 tatgcttaac attagctttt cctgcatatt tattaaaaat tagcagatcg ttcgaggtta
    26341 ttttattaga ggaaaaaata aaaaatagta aaatcaaaat ctgtgacaaa gatagaattg
    26401 aacgagagat actggtgaaa aagaacctaa tagatgaact attgtttcct aatagagtta
    26461 ttaaaaaata tacactgaca attttaattt acagtatagg tattattatt cttttactac
    26521 tttgtaatat gttaagttat ggaattggtg aaaatgtcaa ttttatctgg agattactag
    26581 cttgttatgt aacgagtgtc acagtgatta tagttgcctt gattataatg ataatgatgt
    26641 ttgatcttat aattggatta ctattaaatt ttcaaatatt tttaaaaaat aaaaagtatg
    26701 atgacttttt ataattattc gatttatata atgaaaaatt aaatgattaa acatagaaac
    26761 ctcaaaacaa accatattta atagagttta tggcgcctta tacaaataaa ggctatgctg
    26821 ttaaagaatt atgtagctat cttcagatta atatggatga tgtttatact attggcgata
    26881 gaaaattgat ttacctatgt ttaataccct agataattct tctgataatt tagtttttgt
    26941 tagagtttaa cataactgat gattatcaga agtttcatca ctataaaagg tgtatcaaag
    27001 atttatactc ccttgataca ccttttacat tcatttttaa ttaccgaaga atcgactcca
    27061 aaatcccttt ttaggtggtt ctacctccct attatcatca ggatcattct tcgtttcttc
    27121 aacgaactta tcctcttttg ttaattcacc ttcatctgta ctgtcattct ttttctcttc
    27181 ggctatatcc ttgtaattta cttctgttgg ttgacgcttt gtttgttgtt ggttgatatt
    27241 ttgcgattct tcagtaaaag ttgcttcttg cggattaata ttttgtctat tattcgtcgc
    27301 tgtatcaaaa gaataattaa gctgtctttc ttcttctaat tgactttcta gtttttgaat
    27361 ttttttattg ctttctaaag ctaatatttg ttgattctcc aacaatttat ttaacgtatt
    27421 aacattgcta ttttgttgat ctaattgctt agttaaattc tcaatatatt tttcatcatt
    27481 tttagctcta gtttcaaaga tttctatttg cttttctaat tcgtttactt ttgtttttaa
    27541 tgtctcagaa ctatttgaat tattatatat attcttttct gattttgcag tattttcacc
    27601 aaacaattct ttttttactg attctttatt ttggattgta ctctctttct tagtaatttt
    27661 ttctataatt ttcaaataat cattatcatc aatataatta atcccatttt ctttttcaaa
    27721 agttatattt aaacttttag cattattaac aatagtttgt ttagttacac ctaattcatc
    27781 agcaaccatt ttaatagttc tcataacatc cacccttagg tacctaattt agtacctaaa
    27841 ttttaccacc taatgaattt tatttcatca attaccacta aatttactac ctatttacta
    27901 catatgcacc taattagcta cctataatat gtttttggag cttaattagg tactaaaaca
    27961 atgaactaca cattttgcca tggcaatgtg cttttaacta catttaaaac tctttatata
    28021 ctttcttaaa agtgttaata ttgctttata aatactaaaa gagtcaatgc tattggcgta
    28081 gcattgactc tcggtaataa aacgattcgc actcgtttgt ttatatattt tttgatactt
    28141 gtattatatc tatctaatca tctaagtgca agcacaaaac atataactta cgtaaaaatt
    28201 gttttattac ctcaatccta aaaatggaaa tgaggttttt att
//
