LOCUS       NZ_CP107158            24413 bp    DNA     circular CON 14-AUG-2023
DEFINITION  Escherichia coli strain R11 plasmid pR11-698-3, complete sequence.
ACCESSION   NZ_CP107158
VERSION     NZ_CP107158.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN31158871
            Assembly: GCF_030707895.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24413)
  AUTHORS   Jaen-Luchoro,D., Kahnamouei,A., Yazdanshenas,S., Lindblom,A.,
            Samuelsson,E., Ahren,C. and Karami,N.
  TITLE     Comparative Genomic Analysis of ST131 Subclade C2 of ESBL-Producing
            E. coli Isolates from Patients with Recurrent and Sporadic Urinary
            Tract Infections
  JOURNAL   Microorganisms 11 (7), 1622 (2023)
   PUBMED   37512795
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24413)
  AUTHORS   Jaen-Luchoro,D., Kahnamouei,A., Yazdanshenas,S., Lindblom,A.,
            Samuelsson,E., Ahren,C. and Karami,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2022) Infectious Diseases, University of
            Gothenburg - CCUG, Guldhedsgatan 10a, Box 7193, Gothenburg, Vastra
            Gotaland 40234, Sweden
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 392x
            Sequencing Technology :: Illumina NovaSeq, Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 08/11/2023 07:50:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,294
            CDSs (total)                      :: 5,181
            Genes (coding)                    :: 4,975
            CDSs (with protein)               :: 4,975
            Genes (RNA)                       :: 113
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 206
            CDSs (without protein)            :: 206
            Pseudo Genes (ambiguous residues) :: 0 of 206
            Pseudo Genes (frameshifted)       :: 71 of 206
            Pseudo Genes (incomplete)         :: 151 of 206
            Pseudo Genes (internal stop)      :: 38 of 206
            Pseudo Genes (multiple problems)  :: 48 of 206
            Pseudo Genes (short protein)      :: 3 of 206
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP107158.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24413
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="R11"
                     /isolation_source="human"
                     /db_xref="taxon:562"
                     /plasmid="pR11-698-3"
                     /geo_loc_name="Sweden: Gothenburg"
                     /collection_date="2018"
     gene            complement(71..343)
                     /locus_tag="OGM40_RS26265"
                     /old_locus_tag="OGM40_26235"
     CDS             complement(71..343)
                     /locus_tag="OGM40_RS26265"
                     /old_locus_tag="OGM40_26235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001272119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001272119.1"
                     /translation="MSAFIFRTTFKATGDQQKDAITQIEVMQEQAVKAFVSWMTNQEGT
                     EFLSTLQEITTELDALIDAVESHSPVFRKKATELEALLAHYKTLL"
                     /name="hypothetical protein"
     gene            complement(1300..1935)
                     /locus_tag="OGM40_RS26270"
                     /old_locus_tag="OGM40_26240"
     CDS             complement(1300..1935)
                     /locus_tag="OGM40_RS26270"
                     /old_locus_tag="OGM40_26240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001371526.1"
                     /GO_process="GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA family replication protein"
                     /protein_id="WP_000088100.1"
                     /translation="MSRKRRRFLNRWIKSLTTVAGRIKIKNELRRRIRHNRYWVNEANK
                     FGIEALCELMLAILDDLDLRSWETRHNLETLAERAGLVTRSDAGHKSISRASRGCDRLV
                     WLNAIITEKAPFNPYDARCACKHIEVTEDFFAILGIPLKLVYRERARLLKADPDEVIYS
                     GDARLIAIRVQNWTRKAAAGLARMKAKRDAARQRKKEYYAHSPTPIPA"
                     /name="RepA family replication protein"
     gene            complement(2583..2948)
                     /locus_tag="OGM40_RS26275"
                     /old_locus_tag="OGM40_26245"
     CDS             complement(2583..2948)
                     /locus_tag="OGM40_RS26275"
                     /old_locus_tag="OGM40_26245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248966.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000248966.1"
                     /translation="MVPKRLKEARMEAGLSQEKLSQLLGVAEGINTRSRFSSYEVGRTE
                     PPFKLVKKIAELLDYPENYFYTEDDDFAKAVLDFHRKRTSPELNPNYDSEVEARRMASK
                     LDNVKKIVAQLNEYLKE"
                     /name="helix-turn-helix transcriptional regulator"
     gene            3203..3652
                     /locus_tag="OGM40_RS26280"
                     /old_locus_tag="OGM40_26250"
     CDS             3203..3652
                     /locus_tag="OGM40_RS26280"
                     /old_locus_tag="OGM40_26250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011998906.1"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination NusG
                     family protein"
                     /protein_id="WP_000995159.1"
                     /translation="MNAWYLLYCNNNDLDRIAYRCKTMNVVAFCPRYIKITPRKDCNAV
                     RKEEKVLFPNYLFLHFDVNVTHTSAITSIPGAIGFVSFGSTICTVPEKVVIAIKCAKIL
                     ALNPDDDSIECRNIGSDLLAEIQRISSIISPLERQTAFSRLLQNQ"
                     /name="transcription termination/antitermination NusG
                     family protein"
     gene            3729..3941
                     /locus_tag="OGM40_RS26285"
                     /old_locus_tag="OGM40_26255"
     CDS             3729..3941
                     /locus_tag="OGM40_RS26285"
                     /old_locus_tag="OGM40_26255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001133545.1"
                     /translation="MPNPIGQAKSTAVIYIGKKRYETLAKHARDISYVAEVNIRPSAFL
                     QYMIDKLSNEAHNEMLKELMSKEDK"
                     /name="hypothetical protein"
     gene            3942..4148
                     /locus_tag="OGM40_RS26290"
                     /old_locus_tag="OGM40_26260"
     CDS             3942..4148
                     /locus_tag="OGM40_RS26290"
                     /old_locus_tag="OGM40_26260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001125884.1"
                     /translation="MPKPTYNVYVTQEVPTDENGGKNTYWTKVGAAFAHNGKPGLNIML
                     VPGIAVSGKLVLLEPKEDAPQGN"
                     /name="hypothetical protein"
     gene            4164..4868
                     /locus_tag="OGM40_RS26295"
                     /old_locus_tag="OGM40_26265"
     CDS             4164..4868
                     /locus_tag="OGM40_RS26295"
                     /old_locus_tag="OGM40_26265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_000953548.1"
                     /translation="MLSTVSFMAVAMQCAATVHPSTSLDVARVESGFNPYAIAEIIPKR
                     ERQPGDKGFISHMPKTKEDALSIVKQIEAKGRRYSVGLMQITSTNFNSYAVTAADLFNP
                     CTNLSVFEKIITDCYQRGGTLKRALSCYYSGNFTTGQQPEAALSRTSYIQRIGYSPEKP
                     RYVVPGTRDDIATQSAILNATPVEAPTRPRVVWPGAIVRGVPAQLRQKKADTVYYPAQV
                     IRGNRFSTEKED"
                     /name="lytic transglycosylase domain-containing protein"
     gene            4872..5168
                     /locus_tag="OGM40_RS26300"
                     /old_locus_tag="OGM40_26270"
     CDS             4872..5168
                     /locus_tag="OGM40_RS26300"
                     /old_locus_tag="OGM40_26270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012885319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000608756.1"
                     /translation="MINKLKAICSRASAYILAPLVSVVSPVFAADGFSRANTIMEKVSN
                     GLHGLAAVTITVAVIWIGYKTLWKGESLSQCGYIIIGGILIGGGSEIGALLMS"
                     /name="TrbC/VirB2 family protein"
     gene            5181..7925
                     /locus_tag="OGM40_RS26305"
                     /old_locus_tag="OGM40_26275"
     CDS             5181..7925
                     /locus_tag="OGM40_RS26305"
                     /old_locus_tag="OGM40_26275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="WP_001096401.1"
                     /translation="MAKLLKAMKRPAALWGVPMVPLLTVVGVTIIVAIWTSIALLLFLP
                     IEFLVMKSLTRNEPLRFNLIAVWLRVRGNPVANRLFGATAFMPVEHNAVDIQEFIDAMK
                     LNQCATIKKYIPYSSHIHPNVVRSLNSDFFCTWELTGTPFDCESDETLQFGTNQLHGLI
                     RSFEGFPVTFYVHNSREQFTDSLHKVSGNPYADTVSERYYASLNKRPFRRNRLFVTICY
                     RPFASLDKANRKRMKDGQKLKEIDSALLEVLEIKSTLDTALSRYGAHALGTFTENEAVF
                     SSQLAFYEYLLTHQWRKVRVTRTPAYNVMGNVALYFSAESGQINHVNGTQYFRGLEVKE
                     FSEETATGMTDSLLYAPCDYVITQSYTCMSREEAKKAIKRTRRLMMSADDDAVSQRLDL
                     DVALDLLTSGKIAYGKHHLSIMVFSPSLESLIADTNEISNALNNIGITPVPAEISLSAA
                     YMAQLPGNYNLRPRAGELSSLNFVELASLHNFYPGKRDKAPWGDAMALVRTPSGDGYYL
                     NLHNTLADKDEFNEKNPASTCILGTNGSGKTMLMTFLQINQQKYNRDDSFSPDARTKRL
                     TTVYLDKDRGAEINIRALGGKYYRVFSGEPTGWNPFALPATKRNINFIKQLMKILCTRN
                     GATITPRDERRLNDAVNAVMSDEPQYRVYGITRMLENLPEPATREAQENGLSIRLSQWA
                     RGGEFGWVFDNEHDTFDISNCDNFGIDGTEFLDDPNVCAPISFYLLYRITSLLDGRRLV
                     IFMDEFWKWLRDPVFKDFAYNKLKTIRKLNGMLVVGTQSPAEIIKDEIAPAVIEQCGTQ
                     ILAANPSADRSHYVDGMKFEPEVFDVIKGLDPQARQYVVVKNQFRRGDTKRFAARITLD
                     LSGIGRYTKVMSGDAPNLEIFESLYQEGMKPSDWLDSYLAKAL"
                     /name="VirB3 family type IV secretion system protein"
     gene            7940..8644
                     /locus_tag="OGM40_RS26310"
                     /old_locus_tag="OGM40_26280"
     CDS             7940..8644
                     /locus_tag="OGM40_RS26310"
                     /old_locus_tag="OGM40_26280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010617328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000819778.1"
                     /translation="MKRFRPLILAVLIASPIVNAAGIPVFDATARLENIRQWTKEANQW
                     LQTVQHYKDQLQAYQKQLETVTGIRDIQAFVNQAKSLKADLDKLRKPGQALNDLLLSGG
                     SSGQFDELYNKYKIFDNCNAEQSKSYANTCRQEVINKAIQIEQTNEVQTQIGEMLGEIN
                     ELSDRVANAKDMKEAQDLANSIQLKSVMLNTLTTQWEMNVKAAEKREKMLADERRKKWN
                     QQQLNAPEIMFN"
                     /name="type IV secretion system protein"
     gene            8656..8883
                     /locus_tag="OGM40_RS26315"
                     /old_locus_tag="OGM40_26285"
     CDS             8656..8883
                     /locus_tag="OGM40_RS26315"
                     /old_locus_tag="OGM40_26285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010617327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000720509.1"
                     /translation="MKKIILFTIISGLMALTSGCKEEAKTTKWYREHPDELKVVYAECQ
                     KTGSASENCKHANEAHWQIQQLNAPEISFN"
                     /name="EexN family lipoprotein"
     gene            8893..9963
                     /locus_tag="OGM40_RS26320"
                     /old_locus_tag="OGM40_26290"
     CDS             8893..9963
                     /locus_tag="OGM40_RS26320"
                     /old_locus_tag="OGM40_26290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_024187435.1"
                     /translation="MMAGIFSSVEKNIIGGITDATNGLMMSYSSMMMGLAATSATIYIM
                     WRGYQTLAGKLSTPMEDVMWDIMRMAIILSFVANINGYLDGVIDAVNGIKEGFSSSTSI
                     WQLLDTLWNSARVLGKTLHDLDNSEFIKEEGTIAELFVWGGVFVLMIITAFVSMIAEIM
                     ILLLGITAPIFIFCLMYGFLRPMFNNWLQNIFAAILTIMFSALALRIVIGFLTSRMSEA
                     VTQASKANIVELGAQVCLAGVCAAILVYMSAKLAGALAGASATATMQGAAALGIGAAAY
                     GAGKMLKEAGKVLPKEVASPSNKGLGDPQSRIVFNAADARKHAIEQMIARNEARMLTDQ
                     SAPKLPPSIKRLPPPR"
                     /name="type IV secretion system protein"
     gene            10013..10156
                     /locus_tag="OGM40_RS26325"
                     /old_locus_tag="OGM40_26295"
     CDS             10013..10156
                     /locus_tag="OGM40_RS26325"
                     /old_locus_tag="OGM40_26295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016157224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000825480.1"
                     /translation="MKRLIALALLCVLSGCAQKSKSLPHAFSGQGSPVNTPQIIAELTT
                     HD"
                     /name="hypothetical protein"
     gene            10149..10832
                     /locus_tag="OGM40_RS26330"
                     /old_locus_tag="OGM40_26300"
     CDS             10149..10832
                     /locus_tag="OGM40_RS26330"
                     /old_locus_tag="OGM40_26300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000139290.1"
                     /translation="MTEQKLIADSRSFEQQMIDRDKRATKAGFLVGGAGLLITILSLIA
                     IVIMLPLKQTTVELYTVDNHTGRVEHVTRASKTALTAEEAYQKAMAANYVKLRERYVYP
                     ALQDDYETVQIYNSPQVNDDYLALYAGKNAPDKVYNNAAHTVKIEIISEQITNATAPDK
                     VATVRYKKIIRRMADNSIRNEYWDARFTFHSDPEKEMSDVEREINPFGFTVTSWQTDRE
                     IRGGE"
                     /name="type IV secretion system protein"
     gene            10832..11737
                     /gene="virB9"
                     /locus_tag="OGM40_RS26335"
                     /old_locus_tag="OGM40_26305"
     CDS             10832..11737
                     /gene="virB9"
                     /locus_tag="OGM40_RS26335"
                     /old_locus_tag="OGM40_26305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_001230135.1"
                     /translation="MRKLTLITLIIMLNSQAWAAATPQASRYDARIQQVIYNPQNVTVV
                     NTKPGFMTTLVFDNDEAVISASPGFDEAWEARADANRVNIRPVALTQGAPGEDGNTTQV
                     VIPPNSRDWHTNMLIVTNKRLYNVELNVIDEKSPQQPAYLVSYRYPGDERNRANKEAAA
                     RQKEWEQKQEQTQIQKALRTAQTPRNWDYTKYPGKDSYNIEPDFAYDDGRFTFLGFSPN
                     KSVPSVTKEQNGQEYVVNSSIQRKGNFTVLVIQEITPRLVLRSGDAVVGLKNNGFGKVH
                     AADNSTVSDKVERVEKTDNT"
                     /name="virB9"
     gene            11779..13044
                     /gene="virB10"
                     /locus_tag="OGM40_RS26340"
                     /old_locus_tag="OGM40_26310"
     CDS             11779..13044
                     /gene="virB10"
                     /locus_tag="OGM40_RS26340"
                     /old_locus_tag="OGM40_26310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000129037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_000129037.1"
                     /translation="MTDENKSPSTEEEKPVMTSDQDDIATLEREARAKREAELQASQDD
                     EKENSLQPAVNKLKKRQKGKAAAFLAICAVALIGLTWGGNWVYQNFLKQENGEKTKEVT
                     PPKKTNDYRKRTDLGMATNEPENSTEGEQAVSQDNTGNVSGTAGQMKTFEPPQLNKASF
                     LVRRNNTASPQNQVKTRQQEMILAAENNATQPTDSTATTTQHGTASQAISPATVRRIPY
                     NPDLYIPENTVIPCSMDYRFVSDRAGKIRCTVAKDIWSASGNTKLIEKGTTATGIYQTG
                     ITQGQGRAFIMMTKLRTRQRPYLDIPLIDTNAAGELGESGVDGWIDTHFWERFGGALMV
                     GMIPDIGAWASNNAGKKDRNTDYTENSRQAMADMARTTLENSINIPPTLYKNQGEIINL
                     ITGQDIDFSNIYTLRLKNELQR"
                     /name="virB10"
     gene            13028..13219
                     /locus_tag="OGM40_RS26345"
                     /old_locus_tag="OGM40_26315"
     CDS             13028..13219
                     /locus_tag="OGM40_RS26345"
                     /old_locus_tag="OGM40_26315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000995652.1"
                     /translation="MNCKDKETWLHMLAAGHMGGLAGNPNEAAAQDAYQRLIKNKTAQA
                     VLQRCTTRITLKGANDDR"
                     /name="hypothetical protein"
     gene            13209..14234
                     /gene="virB11"
                     /locus_tag="OGM40_RS26350"
                     /old_locus_tag="OGM40_26320"
     CDS             13209..14234
                     /gene="virB11"
                     /locus_tag="OGM40_RS26350"
                     /old_locus_tag="OGM40_26320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125556.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_000125556.1"
                     /translation="MTAKNISLDRYKQRFFGDFLELPGLTEIAVNRPGELWTKIDGVWG
                     QHTVDLKFDDCYNFARCLAKHHNDNIEDIKPGLSATLESGERCQVVVPPACERDTISIT
                     IRKPSKIQIPHQAYIDSGFYNRVTGIEKASTHNEELIELYKSKNIPLFMEKCVEYGKTL
                     AVAGETSTGKTTYMKMLIQYIPVHLRITTIEDNPEIIFYKHKNYVHLFYPSESSDEKGS
                     VVTPAALIRWNYRMNPDRILLTEVRGGEAWDFLKITGSGHEGSMTSIHAGSAHEAIDGF
                     ITRCTENPQCAQLPYSFLLRKVLDSLDVVVSIDLDGNVRRMNDIYFRPLHRNQYYEEMK
                     V"
                     /name="virB11"
     gene            14231..14629
                     /locus_tag="OGM40_RS26355"
                     /old_locus_tag="OGM40_26325"
     CDS             14231..14629
                     /locus_tag="OGM40_RS26355"
                     /old_locus_tag="OGM40_26325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_021533590.1"
                     /translation="MIKHILVTVLVTLITGCSSPPPPVPVEWNKKPVSLNEKLPEWNPN
                     SLIIKSPVINDKWTLSISSQDFNKEDWMPSVFYAIAHSTQITVATKSGADYFSAKNWLY
                     HHGANGVIIYHPITNCLTCNETTIYFSR"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            14658..14957
                     /locus_tag="OGM40_RS26360"
                     /old_locus_tag="OGM40_26330"
     CDS             14658..14957
                     /locus_tag="OGM40_RS26360"
                     /old_locus_tag="OGM40_26330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000716758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_000716758.1"
                     /translation="MKKIAAITMFVLTTATPVYSYAADPCEVVLCMYGKATGNSGGGEC
                     RSAEKAFFNILKKKKGSIRWSKTFDARKAFLNQCSSADPAAISKIMSKFGRVRG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            14960..15175
                     /locus_tag="OGM40_RS26365"
                     /old_locus_tag="OGM40_26335"
     CDS             14960..15175
                     /locus_tag="OGM40_RS26365"
                     /old_locus_tag="OGM40_26335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001090643.1"
                     /translation="MNTDENMVFYLTNSDLVYSYAHKIVCSIPSGMKGNFITSIGETLE
                     DLKKRYPDIILITESEALALQSKREN"
                     /name="hypothetical protein"
     gene            15203..15508
                     /locus_tag="OGM40_RS26370"
                     /old_locus_tag="OGM40_26340"
     CDS             15203..15508
                     /locus_tag="OGM40_RS26370"
                     /old_locus_tag="OGM40_26340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000910475.1"
                     /translation="MLKEDMFINNIHSRNQDRIHVKRVFDDISNKANRGCGLYYEIYQA
                     RLMRGLIEHTVKLKSSDANKLISYAASQGYEITEDRYNAAIKAEDECLTEITRAQV"
                     /name="hypothetical protein"
     gene            16318..18045
                     /locus_tag="OGM40_RS26375"
                     /old_locus_tag="OGM40_26345"
     CDS             16318..18045
                     /locus_tag="OGM40_RS26375"
                     /old_locus_tag="OGM40_26345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615560.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA transfer
                     family protein"
                     /protein_id="WP_001068080.1"
                     /translation="MNPHLMQKLNGIADAFSIFLLWLQNSPVILSLLAGLTLPFIFNLP
                     REERKNAPFWLKSVACVSIFFFIFGTMSPLSIHGLSYLFDVLDPNTLLRIPLWIITILF
                     TLAGLAFHLTARRLLAGEIDSLKHRMIKKSKLERNTRTDVRKVKELLPDSIEYNPLDYI
                     DLKKGVFIGLDKDDQPQYITIKEFQKQHAAIIGTTGSGKGITASVLLYQAILLGEAVFV
                     EDPKDDEWAVHVLREACKKAGKKFVVINLNRTNHQLDLLADISHEQLEELFNAGFSLSK
                     KGEAADFYRIADRRAARNVAAIHKTGMTLYDLFNDDNVKSIGEDAPAFLGELEEIALVN
                     SVNAKNGFSLKEIFDNGGCCYIIGSTRNQKIISAQRMILTRLIQIAETRDRINTTPRVV
                     AIFLDELKYHISRPTMEGLGTARDKSVHIFMAFQAIDDLRDCPSDLNGDSVIGAVIENA
                     KFKLIYKIQNPETAEWAAKMTGSILVDDEMRKVRTDLSLTEKVDTDRMIRQAESYYVDS
                     NMFLNLPERVGFVFTSKDLPKATKMSHIPANKETIELLSFETEQIEQHNNNDVPSSGL"
                     /name="type IV secretory system conjugative DNA transfer
                     family protein"
     gene            18055..18789
                     /gene="mobC"
                     /locus_tag="OGM40_RS26380"
                     /old_locus_tag="OGM40_26350"
     CDS             18055..18789
                     /gene="mobC"
                     /locus_tag="OGM40_RS26380"
                     /old_locus_tag="OGM40_26350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000905147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_000905147.1"
                     /translation="MLIHDFYERKRISANNMLCLLNFLKDETYSDFHIIKRKLGFTKKS
                     RNPVYKLLNKALKEGFIIKHEIPSSKRKLTVWGITMQGLAMVVKADDITFPSYFEPSKL
                     KYWTLEHRLLNQRVRISLESKGATEWINGDSAAFIARYSGCSHRPDGVIKQPTGAIMAI
                     ETERTMKTRARYISIINSHLTARDKGNWHYALYVMPDTKSKESLIRLFDSIKTVMRNNT
                     PVPFDAKNREMFIFRTIDELEQ"
                     /name="mobC"
     gene            18793..19257
                     /locus_tag="OGM40_RS26385"
                     /old_locus_tag="OGM40_26355"
     CDS             18793..19257
                     /locus_tag="OGM40_RS26385"
                     /old_locus_tag="OGM40_26355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="WP_000697615.1"
                     /translation="MKILIIFALYILSPSLYANAADIQGKVIRVLDGDTIEILQNKTPV
                     RIRLANIDAPEKKQAYGRWSTDQLKSLIAGQSVRVTYSHNDRYGRIIGRVFTTGGSEAN
                     RFMVQSGAAWVYEHYNTDNALADLQQEARSQKRGLWADPNPVPPWEWRHK"
                     /name="thermonuclease family protein"
     gene            19267..>19572
                     /locus_tag="OGM40_RS26390"
                     /old_locus_tag="OGM40_26360"
                     /pseudo=""
     CDS             19267..>19572
                     /locus_tag="OGM40_RS26390"
                     /old_locus_tag="OGM40_26360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001579148.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            19751..20014
                     /locus_tag="OGM40_RS26395"
                     /old_locus_tag="OGM40_26365"
     CDS             19751..20014
                     /locus_tag="OGM40_RS26395"
                     /old_locus_tag="OGM40_26365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001312455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilI type IV pilus biogenesis protein"
                     /protein_id="WP_001312455.1"
                     /translation="MTIKILVVSNDGHEKLIDLSPDNDLAKITKSLRTAENRMVCVIQD
                     NNRILRWDRSYASRAKNHWRKVAPDRFEILGTVEHIHYVGKC"
                     /name="PilI type IV pilus biogenesis protein"
     gene            complement(20046..20279)
                     /locus_tag="OGM40_RS26400"
                     /old_locus_tag="OGM40_26370"
     CDS             complement(20046..20279)
                     /locus_tag="OGM40_RS26400"
                     /old_locus_tag="OGM40_26370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011998900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000024515.1"
                     /translation="MANVPPKPRNTKGEPPSLEDTQHGFNPTRKNADGRKAQLNLYVDM
                     EVKREFRSIAAANDMKHGELLEAYQEFWKKHH"
                     /name="hypothetical protein"
     gene            complement(20319..20966)
                     /locus_tag="OGM40_RS26405"
                     /old_locus_tag="OGM40_26375"
     CDS             complement(20319..20966)
                     /locus_tag="OGM40_RS26405"
                     /old_locus_tag="OGM40_26375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214917.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_000214917.1"
                     /translation="MTVAIALVNGKGGVKKSSMSRAIATEYTKADWKVLGLDMDVDQGS
                     FLDWGQRRLRYKVEPPVTIQGCGTVSQAKKHIESGIWDLVVIDSAAYATKSLLSLAEIV
                     DLLVLPSGFSVDDLRTTVTTVNALRNKGHSTNKMAVVFVGVSESESEYRTALEYLKPCG
                     VQVINGAIPFMTSFSQAQDKGLALTESPFPGPRQKADEVVQGVIDLLTKLSQ"
                     /name="ParA family protein"
     gene            21332..21682
                     /locus_tag="OGM40_RS26410"
                     /old_locus_tag="OGM40_26380"
     CDS             21332..21682
                     /locus_tag="OGM40_RS26410"
                     /old_locus_tag="OGM40_26380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000269927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000269926.1"
                     /translation="MWTVYFGRLFDEWFEEQELALKRKVLAELKHLEEFGPSLSRPHAD
                     TVKGSRHKNMKELRIQYEGHPIRAFFAFDPIRQAIILCAGDKSNDKKFYDRMIRIADEE
                     FSTHLAELEGKK"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            21679..21978
                     /locus_tag="OGM40_RS26415"
                     /old_locus_tag="OGM40_26385"
     CDS             21679..21978
                     /locus_tag="OGM40_RS26415"
                     /old_locus_tag="OGM40_26385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_001259443.1"
                     /translation="MRTLEEVIAAQSPESQAIIKAMADEMILETGLQMMREELQLSQKQ
                     VADAMGISQPAVTQLEQRGNDLKLATLKRYVEAMGGKLSLDVELPTGKRVAFNI"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(22009..22254)
                     /locus_tag="OGM40_RS26420"
                     /old_locus_tag="OGM40_26390"
     CDS             complement(22009..22254)
                     /locus_tag="OGM40_RS26420"
                     /old_locus_tag="OGM40_26390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001193619.1"
                     /translation="MQTKPTPADVKEARISAGLTLKEAAEIFGYQLNTWQMKESAGKAT
                     RSLSVGEYNYLLLLAGKHPEYVLCKRDTITAEPTTV"
                     /name="hypothetical protein"
     gene            complement(22244..22501)
                     /locus_tag="OGM40_RS26425"
                     /old_locus_tag="OGM40_26395"
     CDS             complement(22244..22501)
                     /locus_tag="OGM40_RS26425"
                     /old_locus_tag="OGM40_26395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000845367.1"
                     /translation="MKTDNVFFKSKGSYSYVVTVDMDNQMYMVRKYVKTYVKSCDKEQV
                     KGKKTVKKLVLDTNLTLPELLDLDNGILADLFTRGNNNAN"
                     /name="hypothetical protein"
     gene            complement(22537..23079)
                     /locus_tag="OGM40_RS26430"
                     /old_locus_tag="OGM40_26400"
     CDS             complement(22537..23079)
                     /locus_tag="OGM40_RS26430"
                     /old_locus_tag="OGM40_26400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000206647.1"
                     /translation="MTTFSEKYQPVFEVVCRILGNGWRVNKLDNYQHRIKLTSTEIRKY
                     SIIIRLERERFFIVGSVDSLVWHGNPSVCTVSLTRNPVGIANDISRKILANALDEIELL
                     REHESALQEKQDKVRIIKGMLSQLLSISPWYGALTGFNADNGLAGKILQNGDDYEMVIR
                     GLNVDQLIKVAGFIKKL"
                     /name="hypothetical protein"
     gene            complement(23207..23740)
                     /locus_tag="OGM40_RS26435"
                     /old_locus_tag="OGM40_26405"
     CDS             complement(23207..23740)
                     /locus_tag="OGM40_RS26435"
                     /old_locus_tag="OGM40_26405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025389.1"
                     /translation="MNIQEALNIFGLSGQLTEKDIKNAFKKAALKYHPDRNPVGAEMMK
                     AVNSAFDFLMANLDKINQYQSPEQSAIYNYGDELENVLKALYGLSGLVYEVIGNWIWIS
                     GNTIEHKEALKEIGCKWAAKKKQWFYRPEEHKSYWNREEHTIEEIRAKYGTSGKFQAGG
                     WQQVEGRARVEARA"
                     /name="J domain-containing protein"
     gene            complement(24111..24410)
                     /locus_tag="OGM40_RS26440"
                     /old_locus_tag="OGM40_26410"
     CDS             complement(24111..24410)
                     /locus_tag="OGM40_RS26440"
                     /old_locus_tag="OGM40_26410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000113288.1"
                     /translation="MARLPYIESTTQQIFIFNTLTLCTIGLIHIETGEKYIVVFTDNNK
                     IRDYKNGVIEELGEITQEDIELIEYYAKKYEKYFDDLKIGEEPLNLKEYIECMQ"
                     /name="hypothetical protein"
     Typing          18056..18786
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.361"
                     /coverage="100.0"
                     /evalue="9.03e-162"
     Typing          5182..7922
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="87.527"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          10150..10829
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="85.463"
                     /coverage="100.0"
                     /evalue="4.2000000000000004e-119"
ORIGIN
        1 taaactccac ttgctttaga tttggattaa ataaagagcc atataacggg gcaattgccc
       61 cgttgaggac ttacagcaac gttttgtaat gggctaaaag cgcttccagt tcagtcgctt
      121 tctttctgaa aacaggggaa tgggactcta ccgcatcaat cagtgcgtca agttctgttg
      181 tgatttcctg caaagtgctt aaaaattctg taccctcctg gttggtcatc caggaaacaa
      241 aggcttttac tgcttgttcc tgcataactt caatttgggt aatagcgtct ttttgctgat
      301 cgccagttgc tttaaatgtg gttctaaaaa taaatgcact cattttaatc tcccgcccct
      361 atggggctaa gtggaaaggg aacctatttc cctttcgatg attttattat acctgcatat
      421 gcaggtattg caactatttt tcactattcg aactgaaaaa ttttccacca ctcaccttta
      481 attccttcgc gtatgtgctc aattcagcaa gggcactatt ccgcttcctc acccactcgc
      541 tcactaacgt tcggtcgcta gggttgcggc gagcggatct actttcctag ggttgtacac
      601 cggaaacgcc gaaatttccg atttccaaac tgacccccaa caggaacctt tttgtgatct
      661 ttctcgatca tattgttagc agttagttaa gttatgctcg atggtgggaa gatgccgcgt
      721 tagcggcatg taaggcgcga aatatagttc catagaatca caaatgctaa ggcgcgccga
      781 tacccctaat caaggacgtt catgtcgcca ggaaccgcgt cagccccctg ctaagccaaa
      841 attgcacgga acttacagct acttaggtgg taggtggtcg tagaccgtcg atgttacagc
      901 gatgataggt gaatgattgt tcgtttttaa tgaccggata tggtgtctct aatgccccga
      961 tgcttgcgag gggtgctacc tttgaggcgc ttgcgccgat gttttttagt tatccacttg
     1021 taaaagggga taacagtaat gtttttcttt ttgcttctct tttagtacgt aagtaactaa
     1081 aagagaagca aaagagtaat tgcgtcatat cgtttgcact tcacttatga ttatccacaa
     1141 gctgtacatc gtttaccctc tggccataac ctatggctgc tctttcctga gcagggagcc
     1201 gcttggaaaa cggaaatatc tcacgctaag actatttttt gtacagagat ttattatgga
     1261 cgtgacgata taccgccata aggcggtaag tagccagcat caggccggaa tgggggtagg
     1321 tgaatgtgcg taatattctt ttttgcgttg tcgagctgcg tcgcgttttg ctttcatcct
     1381 ggctaatccg gctgccgctt tccgcgtcca gttctgaact ctgatagcta taagtctggc
     1441 atcaccggag taaatcactt catcaggatc tgcctttaac agcctggcac gttcccgata
     1501 aaccagtttt aacggaatgc caaggatggc aaagaaatcc tcggttactt caatgtgttt
     1561 acaggcacac cgtgcatcat acgggttaaa cggagccttc tctgtaatga tggcattcaa
     1621 ccaaaccagg cgatcacaac cacgactggc gcgagaaatg gatttatgtc ccgcatcgct
     1681 gcgtgtaacc agtccggcac gttcggcaag cgtttcaagg ttatgcctgg tttcccacga
     1741 gcgtaaatcg agatcgtcca gaatagctaa catcaattcg caaagagcct ctatgccaaa
     1801 cttgttagcc tcattaaccc aatagcggtt atgccggata cggcggcgga gttcgttttt
     1861 gattttgata cgccctgcga ccgtcgtcag cgatttaatc cagcgattga ggaaacggcg
     1921 tcgcttacgc gacacaacgt tatagcatgg actttgtttt gccacccctg acggcgatat
     1981 gcgggggatt aaggagttgt tcttttcagc caccaccgcc cgcacttatt gccggacaga
     2041 ggtcttgtat tgagaaatgc atttgctata atcctttgca ggcacccagc ctgctttgga
     2101 ccccctgatt atcttcttgg accggcaaaa tcgaagagag atatcagggg gttgttgcat
     2161 tcaggggggc taaaatgctt cccccccctt cccctagacg ctgttacggg aacgtcccac
     2221 ccaaaaatcc gtaaaaaccg cacgaaaata gcatgaaccc attcgaagat caattcatcc
     2281 acaaaagatc ccgccgatta ccttcctatt tttctttaaa cttcatctgg ttatataatt
     2341 cttaacaaaa ttgagattaa atactgtaca gcatataact cacgatattc atgctaatgt
     2401 acgcatacat tagcattaat atcgaaaaga aatcggcgat aacaaacgga aaaataacgg
     2461 aatttaatag ggtatttacc gctcgccaca accctagcga ccgaacgtta gtgagcgagt
     2521 gggtgaggaa gcggaaaagc gacttgacca aatggagcac atacgcactg atgcctaagc
     2581 actcattcct ttagatattc atttaattga gcaactattt tttttacgtt atccagctta
     2641 gatgccattc ttcttgcttc tacttccgaa tcgtaattag ggtttagctc tggactcgta
     2701 cgttttcggt gaaaatcaag aacagccttt gcaaaatcat cgtcttctgt atagaaataa
     2761 ttttcaggat aatcaagaag ttctgcgatt ttttttacaa gtttaaaagg tggttcagtt
     2821 ctgcctacct cgtagcttga aaatcgagat cgagtgttaa taccttccgc tacaccaaga
     2881 agttgagata atttttcttg agataatcca gcctccatcc tcgcttcttt cagtcgttta
     2941 ggcaccataa tacaacctcc ctttttttgg gaatcccatc ttacagggcg ttacaggcct
     3001 caaagtcaac ataatgaatc ggggttgatt ttgaatcgag taatgctatt atttctttag
     3061 attcttgata ttgacacgca agaattgctg tataaaatca caactgtgta tttttacagt
     3121 taacacttaa tgagtacgcc agcctaagcc cggcaactta ggacggcgga aaatgggggc
     3181 ttgtgtccgt aaggtgacgc ttatgaatgc atggtatctt ctatattgta ataacaacga
     3241 tttagaccgc attgcatatc gttgtaaaac tatgaacgtt gtggctttct gtccgagata
     3301 cataaagatc acacctcgga aagattgcaa cgcagtacgc aaggaagaaa aagttttatt
     3361 tcctaactac ctcttcctcc attttgatgt gaatgtcacg cacacatcag caataacctc
     3421 tattccaggt gcaattggct tcgtaagttt cggttccaca atatgtactg taccggaaaa
     3481 agtcgttatc gctattaaat gcgccaagat actggcgcta aatcctgatg atgattccat
     3541 agagtgccgt aacatcggta gtgacctact ggcagaaatt caacgcatat cttcaatcat
     3601 ctcaccgtta gaacgtcaaa cggccttctc caggctttta cagaatcagt aaaccagacc
     3661 ttcattcctt ctccagtcgt accgctgtgc ttttgcacac ggatatttca tacaggagct
     3721 ataaactcat gccgaaccct ataggccagg ctaaatctac agccgttatt tacatcggca
     3781 aaaaacgcta tgaaacactg gcaaaacacg ccagagatat aagttatgtt gcggaggtaa
     3841 atattcgtcc aagtgccttt ttgcagtaca tgatcgacaa attaagtaat gaagctcaca
     3901 acgaaatgtt gaaagagcta atgtcaaaag aggataaata aatgcccaaa cccacctata
     3961 acgtatacgt cacacaggaa gttcccactg acgaaaacgg cggtaaaaat acctactgga
     4021 ccaaggttgg cgcggcattc gcgcataacg gaaaaccagg actgaatatt atgctcgttc
     4081 ctggtattgc tgtttccggc aagctggtac tactcgaacc taaagaagac gccccacaag
     4141 gaaactaatt tagcgagggt actatgcttt ccaccgtttc atttatggcg gtggctatgc
     4201 agtgtgccgc cacagttcac ccctccacat cactggatgt tgcgcgggtc gagtctggtt
     4261 ttaatcccta cgctattgct gagatcatcc ccaaacgtga acgccagcca ggcgacaagg
     4321 gctttatctc acatatgcca aaaactaagg aggatgcatt aagcatcgtc aaacagatag
     4381 aggcaaaagg tcgtcgctat tctgttggtc tgatgcaaat cacaagtaca aattttaata
     4441 gttacgccgt aacggctgct gacctgttca acccgtgcac aaatctttct gtttttgaaa
     4501 agatcatcac tgattgctac cagcgaggcg gcacactgaa acgggcgctg agttgttatt
     4561 actctggaaa ttttactaca ggacaacaac cagaagctgc gttatccaga accagttaca
     4621 tacagcgaat tggttactca cctgaaaagc cccgctatgt cgttcctgga accagggatg
     4681 atatcgcaac tcaatcggcc attctgaatg caacacccgt tgaagctccg acacgccctc
     4741 gcgttgtctg gcctggcgca atcgtgcgcg gggttcctgc tcaactgcgc cagaaaaagg
     4801 cagataccgt ttattacccc gcacaagtta tacgcggaaa cagattttca actgaaaaag
     4861 aggattaacc gatgattaac aaattaaagg ccatttgcag ccgcgcatct gcttatattc
     4921 tggctccgtt agtaagtgtt gtcagtcccg ttttcgcggc tgacggtttc agccgagcaa
     4981 ataccatcat ggaaaaggtt tcgaatggtc tgcatggtct ggcagccgtc accatcaccg
     5041 tcgctgtgat ctggattggc tataagactc tgtggaaagg cgaaagcctg tcgcagtgcg
     5101 gttacatcat cattggcggc attttaattg gcggaggcag tgaaattggc gctctgctaa
     5161 tgagctaaga ggccgaacat atggcaaagc tgcttaaggc gatgaaacgt ccggcggcgc
     5221 tgtggggggt gccaatggtg cccctgctga ctgtcgtggg cgtgacaatt attgttgcta
     5281 tctggacttc catagcccta cttctcttcc tccctattga gtttctggtt atgaaatcac
     5341 taaccagaaa tgaacctctg agatttaacc tgatagctgt ctggctaagg gtaaggggta
     5401 atccggtagc aaaccgttta tttggcgcaa ccgcatttat gcctgttgaa cataatgctg
     5461 ttgatatcca ggagtttatc gatgcgatga agctaaacca atgtgccacc ataaaaaaat
     5521 acattcctta ctcgtcacat attcacccta atgttgtccg ttcactgaat agcgattttt
     5581 tctgtacctg ggaactgaca ggaacgccgt ttgattgtga atctgacgag acactacagt
     5641 tcggtacaaa ccagttgcac gggctaatac gctcatttga aggctttccg gttacatttt
     5701 atgtacataa cagccgtgaa cagtttacgg actcactgca taaggtttca ggaaaccctt
     5761 acgcggatac cgtgagcgaa cgctattacg catcactgaa taaaaggcca ttccgacgta
     5821 accgcctgtt tgtgaccatc tgctatcgtc cgtttgccag tctggataag gcaaaccgta
     5881 aacgtatgaa agacggtcag aagctaaaag agatagacag cgcattactt gaagtgctgg
     5941 aaatcaaaag tacgctggat acagccttat cccgttatgg tgctcacgcg ctcggtactt
     6001 tcaccgaaaa cgaggctgta ttctcgtccc aactggcatt ttatgaatac cttctcacgc
     6061 atcaatggcg aaaagtcaga gttacacgta cccccgctta caacgtaatg ggaaatgttg
     6121 cgctgtactt ctccgccgaa tcagggcaaa taaatcatgt taatggcact caatatttcc
     6181 gtggtctgga ggttaaagag ttttcggaag aaaccgcaac gggcatgaca gactccttac
     6241 tgtacgcgcc gtgcgattat gtgattacac aatcctatac ctgcatgtcc cgtgaggaag
     6301 cgaaaaaggc gattaagcgc acccgacggc tgatgatgag tgctgatgat gatgctgtat
     6361 ctcaacgttt ggatctcgat gtggcgcttg acctgctcac ctccggtaaa atcgcctacg
     6421 gtaaacatca tttatcaatt atggtgtttt cgccgtcact ggaaagtctg attgcagaca
     6481 caaacgagat cagcaatgca ctcaacaata tagggataac ccctgttcct gctgaaatct
     6541 cattgtctgc ggcctatatg gctcaattac caggcaatta caatctgcgg ccacgagcgg
     6601 gagagttgag tagcctgaac tttgttgaac tggcatcact tcataatttc tatccaggaa
     6661 aacgcgacaa agccccgtgg ggtgacgcga tggctctggt gcgaaccccg tcaggtgatg
     6721 gctactatct gaatctgcat aacactctgg cagataaaga cgagttcaac gaaaaaaatc
     6781 ctgcaagtac ctgcattctg ggtacaaacg gctcaggtaa aacaatgctg atgacgtttt
     6841 tacaaatcaa tcagcaaaaa tataaccgtg atgacagctt ttcaccggat gccaggacta
     6901 aacgactaac cacagtttac ctcgataaag accgtggtgc tgaaatcaac attcgcgcac
     6961 ttggaggaaa gtactacagg gtattcagcg gtgagccaac aggctggaat ccgtttgctc
     7021 tgccagccac taagcgaaac atcaatttca ttaagcaact gatgaaaatc ctttgtaccc
     7081 gcaacggtgc aaccataacg ccacgtgatg aacgtcgcct caatgatgct gtaaatgccg
     7141 tcatgagtga cgagcctcaa tatcgcgtct acggcataac ccgaatgctg gagaacctac
     7201 cggaaccggc aacgcgtgaa gcgcaagaaa atggcctgag tatccgtctt tcacagtggg
     7261 cgcgcggtgg tgaatttggt tgggtgtttg ataacgaaca cgacactttc gatatcagca
     7321 actgcgataa tttcggaatt gacgggactg aatttctgga tgacccgaat gtctgcgccc
     7381 ctatctcgtt ttatctgctg taccggataa ccagcctgct ggatggcaga cgacttgtta
     7441 ttttcatgga tgaattctgg aagtggttac gcgaccctgt atttaaggat tttgcgtata
     7501 acaagctgaa aactatccga aaactgaacg gtatgctggt tgttggcacg caatctccag
     7561 cggaaataat caaggatgag atagctccgg cagttattga gcaatgtggt actcaaatac
     7621 tggccgccaa cccaagcgca gatcgttctc attacgtgga tggaatgaaa tttgaaccag
     7681 aagtgtttga tgtcattaaa ggacttgatc cacaggcgcg acagtatgtc gttgtcaaaa
     7741 atcagttccg ccgtggagat acaaaacgct ttgcagcccg tatcacgctg gatctgtctg
     7801 gtatcggcag atacacaaaa gtaatgagcg gcgacgcacc taacctggaa atattcgaat
     7861 cactctatca ggagggaatg aagcccagcg actggctgga ttcctaccta gctaaagcac
     7921 tataaccaag gagatatcga tgaaaagatt tcgccccctt attctggcgg ttcttattgc
     7981 cagcccgata gtaaacgctg ctggtatacc cgtgtttgat gcaacagcca gactagagaa
     8041 tattcgccag tggacaaaag aagccaatca atggctacag acggtacaac actataaaga
     8101 ccagctacag gcgtatcaaa aacaactgga aacagttaca ggcatccgtg acattcaggc
     8161 gttcgttaat caggccaaaa gccttaaagc tgacctggat aaactacgta agccagggca
     8221 agccctgaac gatttgctct tatccggcgg ttcttctggc caatttgatg aactgtacaa
     8281 caaatacaag attttcgata actgcaatgc tgaacaatca aaaagttatg ccaatacatg
     8341 cagacaagag gtcatcaaca aagcaataca aatcgaacaa accaatgaag tacaaaccca
     8401 gattggtgag atgcttggtg agatcaacga attatcagac cgtgtagcaa atgccaaaga
     8461 tatgaaagag gcccaagact tagcaaacag tattcagtta aaatctgtga tgctaaatac
     8521 gctcacgacc caatgggaaa tgaacgtaaa agcggcggag aagcgtgaaa agatgcttgc
     8581 tgatgaacgc cgtaagaaat ggaatcagca gcaattaaac gcaccagaaa taatgtttaa
     8641 ttagcaggtg acttaatgaa gaaaatcatt ttatttacaa ttatttcagg cctgatggcg
     8701 ttaacttcag gatgtaagga agaagctaaa acaacaaaat ggtatcgtga acatcctgat
     8761 gaactcaaag ttgtttatgc tgaatgccag aaaacaggta gcgcatctga aaactgcaaa
     8821 catgccaatg aagctcattg gcaaattcaa caattaaatg cacctgaaat aagtttcaac
     8881 taaagggcgt ttatcatggc cggtatattt tcttctgtcg aaaaaaatat catcggtggg
     8941 ataactgacg cgactaatgg tttgatgatg tcttattcgt caatgatgat ggggctggcg
     9001 gctacgtcag ccactatcta cattatgtgg cgaggatatc aaaccttagc gggaaagctg
     9061 tctacaccaa tggaagatgt tatgtgggat ataatgagga tggctatcat tttatccttt
     9121 gtagcaaaca ttaacggata tcttgatggt gtcattgatg ctgtaaatgg aataaaagaa
     9181 ggtttttcca gtagcacaag catctggcaa ttacttgata ctctatggaa cagcgcaaga
     9241 gttttaggta aaacgttaca tgatctagac aactccgaat ttatcaaaga ggaaggcaca
     9301 attgctgaat tatttgtatg gggtggtgtc tttgtcttaa tgattatcac agcattcgta
     9361 tctatgattg cggagatcat gatcttattg ttaggtatta ccgcaccaat atttatattt
     9421 tgcctgatgt atggcttttt acggccaatg tttaataact ggcttcaaaa tatatttgct
     9481 gcaatactaa caattatgtt ttcagcctta gctctgcgaa ttgtaattgg ttttcttaca
     9541 tccagaatgt cagaagcagt gacccaagcc agcaaagcaa acattgtaga acttggcgct
     9601 caagtttgtc ttgccggagt atgcgctgca atactggtgt acatgtccgc aaaactagct
     9661 ggggcacttg caggagcaag tgctacagcc actatgcaag gtgcggcggc tctcggcatt
     9721 ggcgctgctg catacggcgc tggaaagatg ttaaaggagg caggaaaagt attacctaaa
     9781 gaagtagcaa gcccaagtaa taaagggtta ggagatccac aatcgcgcat agtatttaac
     9841 gctgctgatg cacgtaaaca cgctatagaa caaatgatag cgcgtaatga agcgcggatg
     9901 ctgacagatc aatcagcacc aaaactaccg ccatcaatta aacgtttacc tcctccaaga
     9961 taactataaa aatataatta tatttttata gaaatacaaa aaggtacata aaatgaaacg
    10021 cttaatcgcg ctggctttgc tgtgcgtgct ttctggctgc gcacaaaaat ctaaatctct
    10081 gccgcacgca ttcagcggtc agggtagccc tgtaaacaca ccccaaatta tcgcggagct
    10141 aaccacacat gactgaacag aaattaattg ctgattcccg ctcgtttgag cagcaaatga
    10201 ttgacaggga taaacgcgcc acaaaagcag gctttctggt cggtggagca gggttattaa
    10261 tcactatcct gtcactgatc gcgatagtga ttatgttgcc acttaaacaa acaacagttg
    10321 aactctatac cgtagataat cataccggac gagtggaaca cgttacccgt gcatcaaaaa
    10381 cagccctgac agcggaagaa gcctaccaaa aagctatggc cgccaattac gttaaattac
    10441 gtgaacggta cgtttatcct gcattacagg acgattacga gacagtacag atctacaact
    10501 caccacaggt aaacgacgac tacctggcac tgtacgccgg aaaaaacgca ccagacaaag
    10561 tttataataa cgcggctcac accgtgaaaa ttgaaattat ttctgagcag ataacgaatg
    10621 caacagcacc agacaaagta gccaccgttc gttataaaaa aataattcgt cgcatggctg
    10681 ataacagtat tcgcaatgaa tactgggatg cacgtttcac cttccattca gaccctgaaa
    10741 aagaaatgtc agatgttgag cgggaaataa acccgttcgg attcaccgta acaagctggc
    10801 agactgaccg cgaaatcagg ggaggcgagt aatgagaaaa ctgacgttaa ttaccctgat
    10861 aataatgctg aacagccagg catgggccgc agctacacca caagcgagcc gttatgatgc
    10921 acgtatccag caggtcattt ataacccgca gaatgttacc gttgtaaaca caaaaccagg
    10981 atttatgacg actctggttt ttgataacga tgaagctgtt atcagtgcca gtcctggctt
    11041 tgatgaagca tgggaagcca gagcagatgc aaacagggta aacattcgtc cggttgcgct
    11101 cacacagggc gcacctggtg aagacggtaa tacaacacag gttgttatcc cgccgaacag
    11161 ccgtgactgg cataccaata tgctgattgt gacaaataag cgcctgtaca acgttgagct
    11221 gaatgtcatt gatgaaaaat cgccacaaca gcccgcatac ctggtgagtt accgctatcc
    11281 aggagacgaa cgtaacagag ctaataagga agcagcagcg cgtcagaaag aatgggaaca
    11341 aaagcaggaa caaacccaga ttcagaaagc actgagaacc gcacaaaccc cgcgtaactg
    11401 ggactacacg aaatatccag gaaaagacag ttacaacatt gaacctgatt ttgcctacga
    11461 cgacggtcgc tttacgtttc tcggattctc acccaacaaa tcagttccat cagttaccaa
    11521 agaacagaac ggccaggaat acgtggttaa cagcagtata cagcgtaagg gcaattttac
    11581 cgttctcgtt atccaggaaa tcacaccacg gcttgtatta cgttccggtg atgccgtagt
    11641 ggggctgaaa aataacggct ttggaaaagt acacgcggct gataattcaa ccgtatctga
    11701 caaggtggag cgcgttgaaa aaacagataa cacctaatct ataaaaatat aattatattt
    11761 ttatataagg actcatatat gactgacgaa aataaatccc cctctacgga agaagaaaag
    11821 ccagtgatga catctgatca ggatgatatc gccacgctgg aacgagaagc cagagcaaaa
    11881 cgtgaggctg aattacaagc atcacaggac gatgaaaagg agaactcatt acaaccagca
    11941 gtaaacaaac tgaaaaaacg tcagaagggg aaagcagcgg cctttctggc aatatgcgca
    12001 gtagccctga ttggcctgac atggggcggt aactgggtat atcaaaactt cctgaagcaa
    12061 gaaaatggag agaaaacaaa ggaggttaca ccacctaaaa aaacgaatga ctaccggaaa
    12121 cgaaccgatt taggcatggc caccaatgag ccggaaaatt cgactgaggg tgagcaagct
    12181 gttagccagg ataacacggg caatgtatcc ggtactgccg gacagatgaa aacatttgag
    12241 ccaccacaac tgaataaggc cagcttcctt gttcgtcgta ataatacggc cagcccccaa
    12301 aatcaggtaa aaacaagaca acaggaaatg atactggctg cggaaaacaa cgccacacag
    12361 cctacagaca gtacagcaac cacaacacaa catggcactg catcacaggc aatttccccc
    12421 gcaacagtgc gaagaatccc ctacaaccct gatttgtaca taccggaaaa cacagtcatt
    12481 ccatgctcta tggattaccg ctttgtttcc gatcgcgctg gaaaaatacg atgtacggta
    12541 gctaaagata tctggagtgc cagcggcaat acaaaactta tcgagaaggg aaccacagca
    12601 acaggaatat accagacagg aattacgcaa gggcaggggc gcgcttttat catgatgaca
    12661 aaattacgca cccgacagcg accatatctg gatattccgc tgattgatac caacgccgct
    12721 ggcgagcttg gagaatcagg tgttgatgga tggattgata cccacttctg ggagaggttt
    12781 ggcggcgcat taatggtcgg catgatccca gatattggcg catgggcatc aaacaatgcg
    12841 ggtaaaaaag accgcaatac agactataca gagaacagcc gccaggctat ggcggatatg
    12901 gctcgaacca cgctggaaaa cagtatcaat atccccccta cgctctacaa aaaccagggc
    12961 gaaattatca acctgattac agggcaggat attgactttt caaatatcta cacgctgagg
    13021 ctgaaaaatg aactgcaaag ataaagagac ttggttgcac atgctcgccg ccggacacat
    13081 ggggggtctc gccgggaacc cgaacgaagc cgccgcacag gatgcttacc agcgtctgat
    13141 taaaaacaaa accgcacagg ccgttttgca gcggtgtacc accagaatca cactgaaagg
    13201 agcaaacgat gaccgctaag aatatttccc tggaccgcta taaacagcga ttttttggtg
    13261 actttctgga attaccagga ctgacagaaa tagctgttaa tcgtccaggt gaactctgga
    13321 caaagataga tggtgtctgg gggcaacata ccgttgatct gaaatttgac gattgctata
    13381 actttgctcg gtgtcttgca aaacaccata acgataatat cgaggatatc aaaccaggac
    13441 tttctgcaac cctggaatca ggagaacgat gtcaggttgt cgtacctccg gcgtgcgaac
    13501 gtgacacgat ctcaatcacg atccgtaaac cgtcaaaaat tcaaattccg catcaggcat
    13561 atattgatag cggtttttat aaccgcgtca caggcattga aaaagcatcc acacataacg
    13621 aagaattgat tgaattatac aaatcaaaaa acattccttt gtttatggaa aaatgtgtgg
    13681 agtatggaaa aacattagcc gtcgcaggtg aaaccagtac gggtaaaaca acatacatga
    13741 aaatgttgat acaatatata cccgtccatt tacgcataac gacgatagaa gacaacccag
    13801 agataatatt ctacaaacat aagaactatg ttcatctgtt ttatccttct gagtcatccg
    13861 atgaaaaagg ttctgttgta acaccagcgg cgcttatacg ctggaattac cggatgaatc
    13921 cagacagaat tttattaaca gaagtgaggg gtggagaggc atgggatttt ctgaaaataa
    13981 cggggtcagg ccatgaagga agtatgacct ccattcatgc tggttcagcc catgaagcaa
    14041 tcgacggttt tattacccgc tgtactgaaa acccacagtg tgcgcaatta ccatattcat
    14101 tcttgctacg taaagttctc gactctctgg atgttgttgt gagcattgat ttagatggaa
    14161 acgtacgccg tatgaatgat atttatttcc gaccgttaca ccgcaatcaa tattacgagg
    14221 aaatgaaagt atgataaagc atatactggt tactgtgctt gtaacactaa ttaccggatg
    14281 ttcctcaccg cctccaccag tacccgtgga atggaataaa aagccggtat cgcttaacga
    14341 gaaacttcct gaatggaacc ccaatagctt aataataaaa tcgcctgtta ttaatgacaa
    14401 atggacgtta tccattagct cacaagattt caataaagaa gattggatgc catctgtctt
    14461 ttatgccatt gctcactcaa cacaaatcac agtagcaaca aagtcaggcg ctgattattt
    14521 cagtgcaaaa aactggttgt atcatcatgg tgcaaacggg gtaattatat atcaccccat
    14581 cacaaattgt cttacgtgca atgaaacaac catctacttt tcgcgttaac acaaaatatt
    14641 aaacaaaggg ttctgacatg aaaaaaattg cagcaataac aatgtttgtt ttaacaaccg
    14701 ccacacctgt ttactcttat gccgcagacc catgcgaggt tgttttatgt atgtacggaa
    14761 aagctacagg aaacagcgga ggtggcgaat gcagatcagc agaaaaagca ttcttcaaca
    14821 ttcttaagaa aaagaaaggt tcaatacgat ggagtaaaac atttgatgca cgtaaagcat
    14881 ttttaaatca gtgttcatcc gctgatcccg cagctatatc aaaaataatg agtaagtttg
    14941 gtagagttcg agggtaaata tgaatacaga tgaaaacatg gtattttatc tgacaaactc
    15001 cgatcttgtt tatagctatg cacacaagat agtgtgctcc attccatcag gaatgaaagg
    15061 gaatttcatt acttctatcg gcgaaacgct tgaagattta aagaaacgat atcctgatat
    15121 tattctcatt acagaatcgg aagcattagc attgcaatcg aagagggaaa attaacatat
    15181 tctttcagaa ctggagaatc ctatgttaaa agaagatatg ttcattaata atattcattc
    15241 aaggaatcag gacagaatcc atgtaaaaag agtctttgat gatattagta ataaagcaaa
    15301 caggggatgc gggctatatt atgaaatata tcaagcgagg ttaatgcgag ggttaattga
    15361 gcacacagta aaactgaaaa gttctgatgc caataagctg attagttacg ctgcttcaca
    15421 aggttatgaa ataacagaag acagatataa tgctgcaata aaagccgagg atgaatgtct
    15481 gactgaaata acacgggcac aggtctgagg cagaggattg cgtagcaacc cgaagggcgg
    15541 ggcaaattcg ctttgcgaat ttgggcgagt ccgacgcagg gcgtggtgca gttcaggctt
    15601 tctttatttc tggcttcaat ttcgaagaaa ttgttaagac aggaataaag aaagtggtgc
    15661 gtggacagaa aattcaattt cgaagaaatt gttaattttc aggcaccacg cccacccgcg
    15721 aacattcgcc ccaagcgaat tgaagcgggc cggggggagc cgcaaaaatt tttccgcccc
    15781 agcgagaaaa aaggcacgcc cacgtgccgg tttttgtggg gggcttgccc cgcacaccgt
    15841 cgggccaggt aatatttccc gccccagcgg gggatattac cgattaggcg cgaccacccc
    15901 ctttaaagca gcgttccaat tttttcgagc ttgcgaagaa aaaataggct aaacgcgcgt
    15961 cttaaagggg gtggtcgcgc gtagcgcgcg acggtgtgcc gcctttgacc ttgggggttt
    16021 tggtccggcg tccagacggg ccattacccc catgtgacgt gaaggactgg cgttccagcc
    16081 aggccgaaac ggcacacgcc gttgcccgtt cttcgggctt tcaggagcca gacgataact
    16141 tatcggctgg ctcctgaaag aacggataac gggcatgatc gccttaggcg atcacaacgt
    16201 ttttggcttt tattggggta caataatggg gtacagctat ggggtacatt atatccccca
    16261 ttactgtacc ccattgtcgt accccataga ttcactttat gaatggggaa aacaaatatg
    16321 aatccacatc taatgcaaaa gctgaatggt attgctgatg ccttttcaat atttctgtta
    16381 tggctacaga acagccctgt catattgtca ttactggcag gactaacact accatttata
    16441 ttcaacctac cacgagagga aagaaaaaac gctcccttct ggttaaaatc tgttgcgtgc
    16501 gtgtccattt tctttttcat attcggcaca atgtcaccac ttagtattca tggtctgagc
    16561 tacctatttg acgttctcga tcccaataca ctacttagaa taccattatg gataatcaca
    16621 attctcttta cactagctgg attagctttt catttgaccg cgcgacgatt attagcaggt
    16681 gaaatagaca gcctgaaaca cagaatgata aagaaaagca aacttgagag aaatacaaga
    16741 acagatgttc gcaaagtaaa agaattgttg ccagacagca tagaatacaa tcccctagat
    16801 tacattgatt tgaaaaaagg ggttttcatt ggcttagaca aagacgacca accgcaatat
    16861 ataacaataa aagaatttca gaaacaacat gcagcaatca taggtacaac aggttccggt
    16921 aagggcatta ccgcatcggt tttgctttat caggcaattc tgttaggcga ggctgttttt
    16981 gttgaagatc caaaagatga tgaatgggct gtgcatgttc ttagggaagc atgtaaaaaa
    17041 gcaggaaaga aatttgttgt aattaattta aacagaacca accatcaact tgacttactt
    17101 gctgacatat cacatgaaca attagaagaa ttatttaatg caggatttag tctatcaaaa
    17161 aaaggagagg ccgcagattt ttatcgtata gctgatcgcc gcgcagccag aaatgtagcc
    17221 gcaattcata aaaccggaat gacactgtat gatttattca acgatgacaa cgtaaaatca
    17281 ataggagaag atgccccagc atttttaggt gaactagaag aaattgctct tgtaaattcc
    17341 gtcaatgcaa aaaatggatt ttctcttaaa gagatttttg ataatggagg atgctgctat
    17401 atcattgggt caacccgaaa tcaaaaaatt atttctgcac aacgcatgat acttacgcgt
    17461 ttgattcaga tagctgaaac cagagacaga ataaacacaa ctccacgtgt tgttgcaatt
    17521 tttcttgatg agttgaaata tcatatttca cgcccgacaa tggaaggatt aggtacagca
    17581 cgagataaaa gtgtgcatat atttatggcc ttccaggcaa tagatgattt aagagattgc
    17641 ccttctgatc ttaatggcga ttctgtaatt ggtgctgtta ttgaaaacgc aaaattcaag
    17701 ttaatctata aaatccagaa tccagaaaca gcagagtggg cagctaaaat gactggttca
    17761 atattagttg acgatgaaat gaggaaggtg agaaccgact tatcattaac agaaaaagtt
    17821 gatactgacc gcatgataag acaggcagaa agttattatg tagacagtaa tatgttttta
    17881 aatctacctg aaagagtagg atttgtgttc acatcaaaag atttaccaaa agcaactaaa
    17941 atgtctcata taccagcaaa caaagaaacc attgaattgc tatcttttga gacagaacaa
    18001 atagaacaac acaataacaa cgatgtgcct tccagtggtt tatgaggttt tactatgtta
    18061 attcatgatt tttacgaaag aaaaagaata tcagctaaca acatgctttg tcttttaaat
    18121 ttccttaagg atgaaacgta ttcagacttt cacattataa aaagaaaatt aggattcaca
    18181 aaaaaaagca gaaacccagt atataaatta ctaaacaagg ctcttaaaga aggttttatt
    18241 atcaaacatg aaataccatc atcaaaaaga aaattaactg tttggggtat tactatgcaa
    18301 ggattagcaa tggttgtaaa agccgatgac attacgttcc ctagttattt cgaacccagc
    18361 aaactaaaat actggactct tgagcatcgt cttttaaatc agcgagtgag aatatctctg
    18421 gaaagtaaag gcgctactga atggattaac ggtgatagtg cagccttcat cgcacgttat
    18481 tccggctgtt cccatcgccc tgatggagta ataaaacaac caactggcgc aataatggct
    18541 attgaaacag aacgaacaat gaaaactcgt gctcgctata taagcattat aaacagtcat
    18601 cttacggcaa gagataaagg aaactggcat tatgctttgt acgtcatgcc tgacaccaaa
    18661 agtaaagaat cattaatcag actgttcgac tcaatcaaaa ctgtaatgag gaataataca
    18721 cctgtgcctt ttgatgcaaa aaacagagag atgtttattt ttagaacaat tgatgaactg
    18781 gaacaatagt tgatgaaaat attaatcata ttcgcattat atatcttgtc gccttcacta
    18841 tatgccaatg cagcggatat acagggaaaa gttattcgtg tacttgacgg cgataccatc
    18901 gaaattttac agaataaaac gccagtaagg attcgtctgg ccaatattga tgcaccggaa
    18961 aagaaacagg cttacggacg ctggtcaact gaccaactta aaagcctgat tgccggacaa
    19021 tccgtcaggg tgacatattc acacaacgac cgttacggtc gcattatcgg acgtgtattc
    19081 acaacaggcg gtagtgaggc taaccgcttt atggtgcaat cgggtgctgc atgggtgtat
    19141 gagcattaca acacagataa cgctctggca gatctacaac aggaagctcg ctcacaaaaa
    19201 cgaggtttgt gggctgaccc caatcccgtt ccaccgtggg aatggcgaca taaataggag
    19261 attgacatgc aaacaattac cacacgtgaa cagttattag tgaatgggaa agtcctggaa
    19321 agggttgcga cacatatcgt aactggcgct catgggtatg aaacgctttg tacaggtggc
    19381 tataacttac agtacaacca agagcgagta ctggttcaaa attgtgaaaa gctggctgaa
    19441 ggcgaactgc ccatcacctg ccacacttgt ttcgctgtat ggcaggatgc atacaaattc
    19501 aaagatagcg actttgacat aaaatcagga aatttcactg atacaggtct gacagatatc
    19561 acaattggcc agatttcaga accagaagaa gaaagtgtga atattctcta tgcggatcaa
    19621 tacgaaacat tgccaataga acgctatatg acaaatgaag aagtaggcag attagtgttc
    19681 aattttatga aacgcaccaa cggcgaagcg ttactaatag tgtttccaga atatgataat
    19741 ggagacgata atgacgataa aaatactcgt tgtgtcaaat gacggccatg aaaaactaat
    19801 tgatctaagt ccagataatg atttagctaa aattacaaaa tcattgcgta cagcagaaaa
    19861 caggatggta tgtgttatcc aggacaataa tcgtattctc cgctgggaca gaagctatgc
    19921 ctctcgtgcc aaaaatcact ggcgaaaggt agctcccgat cgttttgaga ttttaggaac
    19981 cgttgaacat attcattatg ttggtaagtg ttaatatcag gggacagttc gtcccctatg
    20041 ccattttaat gatgcttttt ccagaattcc tggtatgcct ccagcaactc cccgtgcttc
    20101 atatcattag ccgctgcaat cgagcggaac tcccgtttaa cttccatatc cacataaagg
    20161 ttaagctgag cttttctccc atcagcgttt ttacgcgtcg gattaaatcc gtgttgtgta
    20221 tcctccagac ttggcggctc gcctttggtg ttacgcggtt ttggtggtac attagccatc
    20281 ttatcacctc tataaaaata taattataga attatatatc actgtgagag tttagtcagc
    20341 aagtcaataa ctccctggac aacttcgtca gctttctgcc gtggacctgg aaaaggggat
    20401 tccgtcaatg ccagtccttt atcctgtgcc tggctgaacg aggtcataaa aggtattgcg
    20461 ccattgataa cttgaacacc acacggttta agatattcaa gcgcggtacg atactcactt
    20521 tcgctttcac tgactccgac aaaaactaca gccatcttat ttgttgagtg tcccttgtta
    20581 cgcaatgcat tcacggttgt aaccgtcgtt ctcaaatcgt ccacactaaa accagacggt
    20641 aacacgagca aatcaacaat ttctgccagg ctcaacagcg atttagttgc ataagcagca
    20701 ctatcgataa cgactaaatc ccatatccct gattcaatat gttttttagc ctgtgatacc
    20761 gttccgcatc cctgaatagt gacaggtggt tcaactttat atctcaatcg ccgctgtccc
    20821 caatccagga atgacccctg atcaacatcc atatcaagcc ctaatacctt ccagtctgcc
    20881 ttcgtgtact ctgtggcaat agccctgctc attgaggact ttttcacccc gcctttaccg
    20941 ttaaccagcg caatagctac cgtcatacga ccccctataa aaatattttt atataaaaat
    21001 ataattatag tatccgtatt ggtgccaaga attgcaacaa ctatttgaac tacaggcggc
    21061 aagtgaagag ataacttgtg aatataaggc tttcacaacc aaattcagcc aaaacaaaaa
    21121 atgacgtttt attaacaaat acgcaacata aaaaacggtg gaaaacgccc aggaaaacat
    21181 gatcttttga gcggattttg cagatccgac aacgaacggt gatccgatgg tgccgataac
    21241 gtccattatg ttaaatagcc ccgtttccct tgaaattata agtcgtagct tatacaatca
    21301 tctataagct ataacttata ggaaaaggga catgtggact gtttattttg gcagattatt
    21361 tgatgaatgg tttgaagagc aggaactagc cctaaaacga aaagtgctgg ctgaacttaa
    21421 acatcttgaa gagtttggcc cctctctttc acggccacat gcagatacag tgaaagggtc
    21481 acgtcataag aatatgaagg aactacgtat acaatatgag ggacacccaa tcagggcatt
    21541 ctttgcattt gatccaatta gacaagcaat cattctttgc gctggcgaca aaagtaatga
    21601 taagaaattt tacgacagaa tgattcgtat tgctgacgaa gaattttcca ctcacttagc
    21661 cgaactggag ggcaaaaaat gagaacatta gaagaagtaa ttgcggctca atcacctgaa
    21721 agtcaggcga tcatcaaagc tatggctgat gagatgattc tggaaacagg gctgcaaatg
    21781 atgcgtgaag aattgcagct ttcacaaaaa caggttgctg atgcaatggg aatcagtcag
    21841 cccgctgtaa ctcaactgga acagcgcgga aatgatttga agctggcaac gttaaagcgt
    21901 tacgttgaag ctatgggagg aaagttgagc ctagatgttg aactccctac cggaaagcga
    21961 gtggccttta acatttagta gaaaaggggc gaaaagcccc ttttggggtc agacagtggt
    22021 tggttctgcg gtgatcgtat cccttttaca aagaacatat tcagggtgtt ttccagccaa
    22081 caacaataag tagttatatt cacctacaga taaagacctt gtagctttac ctgcgctttc
    22141 tttcatttgc caggtattta actgatagcc aaaaatttcg gcagcttcct taagcgttaa
    22201 acctgcggaa attctcgcct ctttaacatc tgccggagtt ggtttagttt gcattgttat
    22261 tacctcttgt aaataaatca gccagaatac cattatcaag atccaataat tctggcaatg
    22321 taagattcgt atcgagcacc aattttttaa ctgtcttttt ccctttaact tgctctttat
    22381 cacaagattt cacatatgtc ttaacatact ttctgaccat atacatctga ttatccatat
    22441 ctactgtaac aacataagag taactaccct tacttttaaa gaaaacatta tcagttttca
    22501 taaacaaccc catataaaat tcacatcaac actttgttat agttttttta taaaacctgc
    22561 cactttgata agttgatcaa cattaagccc tctgataacc atttcataat catcaccatt
    22621 ttgtagtatt tttcctgcaa gtccattatc cgcattaaat cccgttaatg ccccatacca
    22681 gggagatata gaaagcaact gtgataacat ccctttgatt attcgcactt tatcttgttt
    22741 ttcctgtaat gcgctctcat gctccctgag caattcaatt tcatccagtg cattagcaag
    22801 gattttccga gatatatcat tagcaatacc aacaggattg cgcgtaagag atacagtaca
    22861 gacggaagga ttaccgtgcc atacaagact atcaacgcta ccaactataa aaaatctttc
    22921 acgctccaga cgaataatga tggagtattt acgaatttct gtagaagtca gtttaatacg
    22981 atgctgataa ttatccagtt tgttaacacg ccagccgttc ccaagaatac ggcatacaac
    23041 ttcaaagaca ggctgatatt tttctgaaaa tgttgtcatg ctttcaaatc ctttactgcg
    23101 ctaacgtagc cagcaatcgc agagtgtcag ctactcaatc cttttcgggt tcgatgcccg
    23161 aaaaggattg ctggcgagga tatagggggc ttacgccccc gtttcgttat gctctggctt
    23221 caactcttgc cctgccttca acttgttgcc atcctccggc ctggaatttt ccgcttgtgc
    23281 catattttgc gcggatttcc tctatcgtgt gctcttcacg gttccagtaa cttttatgtt
    23341 cttctggacg ataaaaccat tgttttttct ttgccgccca tttacaccct atttctttta
    23401 atgcttcttt gtgctcgata gtatttccac taatccagat ccagttacca ataacctcat
    23461 aaactaaacc agacaaaccg taaagagcct ttaaaacatt ttctagttca tcaccatagt
    23521 tatatattgc actttgttca ggactttggt actgattaat cttatcaaga ttcgccatta
    23581 aaaaatcgaa tgctgaatta accgccttca tcatttcagc acctaccgga ttacggtctg
    23641 ggtgatattt taatgcagct ttcttaaagg cgtttttgat gtctttttca gtcaactggc
    23701 cagacaagcc aaaaatattt aatgcttctt ggatattcat tttgtagctc ccgcccctgt
    23761 ggggctaaga tgagagggaa accatttccc tctcgatgat ttaattatac cttcaattgc
    23821 aggtattgca agttttttag ctctcttttt gaaaaaattt ataattactg tcaggacatc
    23881 aacattgctt aaaacatttc atatccctgt aaataattta accaccacct gaattgatcc
    23941 caatccgtaa atttcattgc tgggattctc gtttcccatc ctttgacaag tgaatccgca
    24001 agttgtacga tctgacctgt tgacatttga acacctctct attgttttga gtgtcgataa
    24061 agtgatcagg ttgctcgacc aacctgatca cacctttata gaatatatgg ctattgcata
    24121 cattctatat attctttaag attcaaaggc tcctcaccta tttttaaatc atcaaaatac
    24181 ttttcatatt ttttagcata atactcaatc agttcaatat cttcttgcgt aatttcccct
    24241 aattcttcta ttacaccatt tttataatct ctaatcttat tgttatctgt aaatactaca
    24301 atatattttt caccagtctc tatatgaatt aatccaatag tacaaagtgt caaagtatta
    24361 aaaataaaaa tctgttgcgt ggttgattca atataaggta agcgagccat ttt
//
