LOCUS       NZ_CP104910             8731 bp    DNA     circular CON 12-OCT-2023
DEFINITION  Acinetobacter baumannii strain YZM-0314 plasmid punamed2, complete
            sequence.
ACCESSION   NZ_CP104910
VERSION     NZ_CP104910.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN30929355
            Assembly: GCF_025449175.1
KEYWORDS    RefSeq.
SOURCE      Acinetobacter baumannii
  ORGANISM  Acinetobacter baumannii
            Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales;
            Moraxellaceae; Acinetobacter; Acinetobacter calcoaceticus/baumannii
            complex.
REFERENCE   1  (bases 1 to 8731)
  AUTHORS   Yang,Y.
  TITLE     Alteration of adeS contributes to tigecycline resistance and
            collateral sensitivity to sulbactam in Acinetobacter baumannii
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8731)
  AUTHORS   Yang,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-SEP-2022) Department of Clinical Laboratory,
            Affiliated Hangzhou First People's hospital, NO.4 Xueshi Road,
            Hangzhou, Zhejiang 310016, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 10.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 10/12/2023 03:22:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,834
            CDSs (total)                      :: 3,739
            Genes (coding)                    :: 3,670
            CDSs (with protein)               :: 3,670
            Genes (RNA)                       :: 95
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 20 of 69
            Pseudo Genes (incomplete)         :: 40 of 69
            Pseudo Genes (internal stop)      :: 17 of 69
            Pseudo Genes (multiple problems)  :: 8 of 69
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP104910.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..8731
                     /organism="Acinetobacter baumannii"
                     /mol_type="genomic DNA"
                     /strain="YZM-0314"
                     /db_xref="taxon:470"
                     /plasmid="punamed2"
                     /collection_date="2017-03"
     gene            complement(109..627)
                     /locus_tag="N7297_RS19145"
                     /old_locus_tag="N7297_19145"
     CDS             complement(109..627)
                     /locus_tag="N7297_RS19145"
                     /old_locus_tag="N7297_19145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447193.1"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_000447193.1"
                     /translation="METFAEPVFSNDLLAKAENGDTSAQLELAEIYLYGHGVDSDENQA
                     EVWALKSAENGNVAAMFWLADGYVTYARLMEDDDKNDSLEHFQKAFKWFQKASENGHSE
                     SMVELADLYTRADSGIEVNINKAFELREKAAKLGNKKAMRSLSVMYRDGIGIPKNTDLA
                     QSWWDKSEN"
                     /name="tetratricopeptide repeat protein"
     gene            1000..1287
                     /locus_tag="N7297_RS19150"
                     /old_locus_tag="N7297_19150"
     CDS             1000..1287
                     /locus_tag="N7297_RS19150"
                     /old_locus_tag="N7297_19150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019383542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnT family toxin"
                     /protein_id="WP_000438826.1"
                     /translation="MEQYFEWDEAKNRKNQKKHDISFETASLVFEDPLRISIQDRHTNG
                     EERWQTIGRVKGVLMLLVAHTIFDEDDCEIIRIISARQVTKAERNKYEHG"
                     /name="BrnT family toxin"
     gene            1274..1588
                     /locus_tag="N7297_RS19155"
                     /old_locus_tag="N7297_19155"
     CDS             1274..1588
                     /locus_tag="N7297_RS19155"
                     /old_locus_tag="N7297_19155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006582675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnA antitoxin family protein"
                     /protein_id="WP_001983304.1"
                     /translation="MSMVRYSHKELNEKFGEKQDAEIQRLLAKGTVPDDQLDLSDIPEI
                     TDWSNAVRQNQFYRPVKQQTSIRLDADVLAWFKAQGKGYQTRMNEILRDAMLKELKNHQ
                     "
                     /name="BrnA antitoxin family protein"
     gene            1716..4127
                     /gene="znuD2"
                     /locus_tag="N7297_RS19160"
                     /old_locus_tag="N7297_19160"
     CDS             1716..4127
                     /gene="znuD2"
                     /locus_tag="N7297_RS19160"
                     /old_locus_tag="N7297_19160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor ZnuD2"
                     /protein_id="WP_000932953.1"
                     /translation="MLNKSKLFLALITLGASKILLAAEGPVTTLNTIVLTAQSDELGSE
                     LLGKSLNVSNQFIDTSKLKQRSTTLGDALGTELGIHSNQYGGGASTPIIRGQEGKRIKV
                     LQNNADVLDMSNMSPDHAVTVEPSLAKSIEIIRGASTLLYSSNSAAGVVNVIDYKIPTQ
                     MPQDGLEGNTTLRFNTGSNEKLTTAGVTVGLSPHVALRAEGLYRNAGNYKTPHYQSSSY
                     NSLEDLENQNSIYKNLKYLPESWAESRVGTLGLSWIDDNTYLGVSYTHRHDEYGLPAHS
                     HLYEGCGASAIGIDSRISGLKNYLLYYPQLMDEQDINYINPRPDCHQHNHIHETNFSHN
                     APYIDLNTRRYDVRGEFTQPFTGIDKIRTSLSYIDYFHNELEGDKITNFFKNTGKVGRI
                     ELSHQPLGELTGILGLQYLEQDNSALSPVHSQEGHTTYLDNQQLLNRNVTKNFSVFGLE
                     KYNWNDFTFELGARIEKQKVSMDYDIEKIKDSMKPWPNKYNSPYVEKNNKIRAQNLKSI
                     LEAVQPNKETAFSYAGTVHWRFAPNYILSLTGTHQERLPNAQEMYTHGMHLATNSFEIG
                     NRFLRKEKSNNLEISLAYKDDLLDYQISTYYYDFDNYIYLQTLNEVLGTTKVRDQHTLR
                     INHYSQSAANFYGLEGNIGYQFNSVYHGSLFGDYVKGRLTNLPDAVIAYDIWNREPTLA
                     PQKDRYTPRLPPARLGTRLKADFDESLKGEIEYYRVFKQDNISKFEQVTSGYNMLNMTL
                     AYKNKLSHTEYDLFFKANNLLDQKVYAHETFLPYIPQIGRNFSLGLNLNF"
                     /name="znuD2"
     gene            4432..4893
                     /locus_tag="N7297_RS19165"
                     /old_locus_tag="N7297_19165"
     CDS             4432..4893
                     /locus_tag="N7297_RS19165"
                     /old_locus_tag="N7297_19165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004781077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DIP1984 family protein"
                     /protein_id="WP_000761346.1"
                     /translation="MKLAEALLLRSDQQKKIISLKQRINANVLVQDGDQPSEDPNELLK
                     QVFSLIQEFQKLSYAIHETNALTKLNDGRSLLALLTLRDEFVEQHKTLTAAISNTSRES
                     DRYSTREIKWHKVIPVSSLQKQADDISLKLRDLNVLIQSTNWKIDLIEA"
                     /name="DIP1984 family protein"
     gene            complement(5216..5389)
                     /locus_tag="N7297_RS19170"
                     /old_locus_tag="N7297_19170"
     CDS             complement(5216..5389)
                     /locus_tag="N7297_RS19170"
                     /old_locus_tag="N7297_19170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001282484.1"
                     /translation="MSDNIIQLSKPCTLCENRQNVQLFAGLMLCGSCQENIRLTNPSMF
                     SANDEIEQKAQN"
                     /name="hypothetical protein"
     gene            complement(5389..5760)
                     /locus_tag="N7297_RS19175"
                     /old_locus_tag="N7297_19175"
     CDS             complement(5389..5760)
                     /locus_tag="N7297_RS19175"
                     /old_locus_tag="N7297_19175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000504218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000504218.1"
                     /translation="MGEKVKTYAVRLDPQVAEFYDQLANSEGIRTSKLFSKILTNDFQS
                     IAVKQQADRIEDLVNRLEKRIDDFEEDNNFSEKYYEDFSGLYFMMLWLLMKNGASKDEV
                     RMIQAKGYSYADDNYKRVK"
                     /name="hypothetical protein"
     gene            complement(6032..6286)
                     /locus_tag="N7297_RS19205"
     CDS             complement(6032..6286)
                     /locus_tag="N7297_RS19205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001014301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001014303.1"
                     /translation="MNGQKIDFLRFSKQGNKYFFPCKTKHRPYVTLANFPIQDPAHAGI
                     FLSHTTHLTMTPLKALQDKDFSDFLGSQKRVQKNGLFLE"
                     /name="hypothetical protein"
     gene            6970..7920
                     /gene="repM"
                     /locus_tag="N7297_RS19180"
                     /old_locus_tag="N7297_19180"
     CDS             6970..7920
                     /gene="repM"
                     /locus_tag="N7297_RS19180"
                     /old_locus_tag="N7297_19180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004786597.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepM"
                     /protein_id="WP_001205343.1"
                     /translation="MRDLVVKDNALINASYNLDLVEQRLILLAIVEARESGKGINANDP
                     LEVHADSYINQFGVHRNTAYQALKDACKDLFARQFSYQEKKANGNIRNVMSRWVSQIAY
                     NDNEATVDLIFAPAVVPFITRLEEQFTKYELQQVSSLSSAYAIRLYELLIQWRSTGKTP
                     TIELQEFRKKLGVLDNEYLRMAHLKERVLELSIKQINEHTDITVKYEQHKRGRSISGFS
                     FTFKQKKKDSPSIERDPNTLELFSKMTDAQRHMFANKLSELPEMGRYSQGTESYQQFAV
                     RIAEMLQDPAQFKELYPYLKKVGYMPSNKKDTVNG"
                     /name="repM"
     gene            7913..8488
                     /locus_tag="N7297_RS19185"
                     /old_locus_tag="N7297_19185"
     CDS             7913..8488
                     /locus_tag="N7297_RS19185"
                     /old_locus_tag="N7297_19185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005102333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication DNA-binding protein"
                     /protein_id="WP_001096616.1"
                     /translation="MAKLSLSEVSKKFHVDRSTIYRAVRNGRLSRSSDGQFDLAEVIRC
                     FGEPEQTSQKIESSKQEGDESTKKLIAHLENEVKKYQEREERLMQQIDRMQTLIELKSV
                     APATAAPHQDATACDTKMPQHATTQQDTDNKKNNELNIAENVAVPQQETTAYHTQTLQH
                     ATLQSVAVPQHKKRGLFGRVLNAVFDND"
                     /name="plasmid replication DNA-binding protein"
     gene            8508..8651
                     /locus_tag="N7297_RS19190"
                     /old_locus_tag="N7297_19190"
     CDS             8508..8651
                     /locus_tag="N7297_RS19190"
                     /old_locus_tag="N7297_19190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004786602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001125246.1"
                     /translation="MPKLKDIALGIIVAPLLIPIMLIASYQDKKALKKELDECQKEKDQ
                     AS"
                     /name="hypothetical protein"
     Typing          6971..7920
                     /name="rep_cluster_1172"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 aacagggatg ctcgggctat aaactagaaa ctacagcgtt gaattataag gataattata
       61 cagcatttcg tataaggtgt attatgttaa ttttaggaaa tattaaaact aattttcaga
      121 cttatcccac caactttgag ctaaatcagt atttttagga atacctatac catcacgata
      181 cataacggaa agacttcgca ttgctttctt attacctaac tttgcagcct tttcacgaag
      241 ttcaaaagct ttattaatat taacttctat tccgctatct gcacgagtat atagatcagc
      301 taactcaacc attgattcag aatggccatt ttctgaggct ttctgaaacc acttaaaagc
      361 tttttggaaa tgttctaaag aatcgttttt gtcatcatct tccattaatc tagcataagt
      421 aacatatcca tcagctaacc aaaacattgc tgctacattt ccattttctg ctgatttaag
      481 agcccaaact tcagcttgat tttcatctga atcaacacca tgaccatata gataaatctc
      541 ggctaattct aactgagcag aagtatctcc attttctgct ttcgctaata aatcattaga
      601 aaaaacaggt tctgcaaatg tttccattga aaggcaaact cctaaagcca taaaaatatt
      661 tgttaattta ttcaattttt aacctttaaa ctaaactgtt aggcttgtat atttttatat
      721 catacctaaa agaaaactct aaaattagag tatgtcttat ctctatttaa cataatggcg
      781 attatacgaa gtacacttgt atattaatat aaatatcaac tacttaataa aaatagaaaa
      841 atcccaaaat gcccaaaaag ccgactttga aacaagtcgg cttttttatg agcagttttg
      901 atacttcttg ccaataattt tgactaaaaa ttacacgaat ctggttgagt gatacaattt
      961 tgtgatacat tattgtatat acaaatttga atgtttttta tggaacagta ttttgaatgg
     1021 gatgaggcta agaatcgaaa gaatcagaaa aagcatgata tctctttcga aactgcaagc
     1081 cttgtttttg aagatccatt acggatctca atccaagaca gacataccaa tggtgaagaa
     1141 cgttggcaaa ccattggacg agttaaaggc gtactaatgt tattggtggc tcacaccatt
     1201 tttgatgaag atgactgtga aatcatccga atcattagtg caaggcaagt cactaaagcg
     1261 gagcgaaaca aatatgagca tggttagata ctcacacaaa gagctgaatg agaaatttgg
     1321 tgagaagcaa gatgctgaaa ttcaacgctt gcttgctaaa ggcacggttc ctgatgatca
     1381 gctagatcta tcagatattc ctgaaattac agactggagc aatgctgtac gccaaaatca
     1441 attttaccgc ccagtaaagc aacaaacttc aattcggtta gatgctgatg tacttgcttg
     1501 gttcaaagca caaggcaaag gttatcaaac acgtatgaat gaaattttac gagatgctat
     1561 gctaaaagaa ttaaaaaatc atcaataaga atgggagctt aggctcccat ttttgacttc
     1621 atttttaggg gggattacca ttcaaaaatt taaatagtag attttataaa tttttaagtg
     1681 ttatattata atataacatt aaatttggtt gttttatgct aaataaaagt aaactatttt
     1741 tagctttaat tactttaggg gcctcgaaaa ttttattggc agctgaaggg cctgttacta
     1801 ccttaaatac aatagtatta actgcacaat ctgatgagtt agggtctgag ctgttaggca
     1861 aaagtctaaa tgttagtaat cagtttattg atactagtaa acttaaacag cgttcgacaa
     1921 ctctagggga tgccttgggt acggaattag gaattcattc taatcaatat ggaggtggag
     1981 catctactcc tattattcgt gggcaggaag gaaaacgtat taaagtttta cagaataatg
     2041 ctgacgtgtt ggatatgtct aatatgtccc cagatcacgc tgtcacagtt gaaccaagtt
     2101 tagctaagtc tattgaaatt atacgtggtg caagtaccct tttgtatagt tcaaatagtg
     2161 cggcaggggt agtcaatgtc attgactata aaattccaac ccaaatgcct caagacggat
     2221 tagagggtaa tactacatta cgttttaata ctggcagtaa tgagaagttg accacagcag
     2281 gtgtaacagt tggcttaagc ccacatgtag ctttacgggc agaagggtta tatcgtaatg
     2341 ctggtaacta taaaactcct cattaccagt ctagctctta taattcttta gaagatcttg
     2401 aaaaccaaaa cagtatttat aaaaatttaa aatatttacc agaaagctgg gcagagtcga
     2461 gagtaggtac gcttggatta tcctggatag acgataatac ttatttagga gtttcttata
     2521 cacatcgtca tgatgaatat ggtttaccag cccatagcca tttatatgaa ggttgtggtg
     2581 cctctgcaat cggtatcgat tcacgaatta gtggattaaa aaattatctt ttatattatc
     2641 ctcaattgat ggatgagcaa gatattaatt acataaatcc acgtcctgat tgtcatcagc
     2701 ataatcatat tcatgaaact aatttctctc ataatgctcc ttatattgat ttaaatactc
     2761 gacgttatga tgtgcgtgga gaattcactc aaccatttac cggtattgac aaaattcgta
     2821 cctcattgag ttatatagat tattttcaca atgaactcga gggagataag attactaact
     2881 tttttaaaaa tacaggaaaa gtaggccgca tagagttatc acatcagcca ttaggggaat
     2941 taaccggtat cttggggcta caatatttgg aacaggataa tagtgcttta tcaccagtcc
     3001 attctcaaga aggccatacc acctatctag ataatcagca gctattaaat cgaaatgtca
     3061 ctaaaaactt tagtgtattt ggcctagaaa aatataactg gaacgacttt actttcgaac
     3121 taggtgctcg tatagaaaag cagaaagtta gtatggatta tgatatagaa aaaattaaag
     3181 attcaatgaa accttggcct aataaatata acagtcctta tgtagaaaaa aataataaaa
     3241 tcagggctca aaatttaaaa tctattttag aagctgttca acctaacaaa gaaacagctt
     3301 tttcttatgc aggtacagtc cactggagat ttgctccaaa ttatatctta tcattaacag
     3361 gtacacatca agaaagatta cctaatgcac aagaaatgta tactcatggt atgcatctcg
     3421 ctactaattc ttttgaaata ggtaaccgct ttctaagaaa agagaaatcc aataatttag
     3481 aaatcagtct ggcctataag gatgatttac ttgattatca aatcagtact tactattatg
     3541 attttgataa ctatatatat ttacagacac tcaatgaagt tttaggaact acaaaagtta
     3601 gagatcagca tacactacgt attaatcatt atagccagtc tgctgctaat ttttatggat
     3661 tagagggcaa catagggtat caatttaatt ctgtttatca cggctctctt tttggagatt
     3721 atgtgaaagg ccgtttaaca aatttacctg atgctgtaat tgcatacgat atctggaata
     3781 gagaaccgac tttagctccc caaaaggatc gttacactcc tagattacct cctgctcgtt
     3841 tgggtacacg actaaaagct gattttgatg aatcgcttaa aggtgaaata gaatattatc
     3901 gagtctttaa acaagataat atttctaaat ttgagcaggt tacatcaggt tataatatgc
     3961 ttaatatgac tttagcatat aaaaataagc tatctcacac agaatatgat ttattcttta
     4021 aagcgaataa tttacttgat cagaaagtct atgcccatga aacatttttg ccatatattc
     4081 cccaaattgg aagaaatttt agtttaggct taaatcttaa tttctagata agatactgta
     4141 atcttctaag aaaatttctt agaagatttt tcttataaaa tgattagatt aataattaag
     4201 gtaagcgtcc gctgaatccc atacctattt tttaattcga tttaggtttc cagcagtgtg
     4261 gcagtaactc ttcaatctgg gtcactttat gtgtcggcag ccttttcagc actgaatagc
     4321 caccgatttt gtagacacct tttagctaga taaaaagcaa tttttttgat ctttaaagaa
     4381 tgaggatata agctgtttaa aacttaattc taattggtta ataggtgaaa aatgaaatta
     4441 gcagaagctc tcttacttcg aagtgatcaa caaaaaaaaa ttatttcact aaaacaacgt
     4501 atcaatgcaa atgtattggt acaagatggt gatcaaccat ctgaagatcc aaatgaacta
     4561 ctaaaacaag tattttcttt aattcaagaa tttcaaaaat taagttatgc aattcatgaa
     4621 actaatgctt taacaaaatt aaatgatggc cgttctctac ttgctttatt gactttgcgt
     4681 gatgaatttg tagaacagca caaaacccta actgcagcaa taagtaatac atctcgtgaa
     4741 tctgatcgtt atagtacgcg ggaaataaag tggcataaag ttattccagt ttcatcatta
     4801 caaaaacaag ctgatgatat tagtcttaaa ttacgtgatt taaacgtgtt aattcagtcg
     4861 actaattgga aaattgattt gattgaagcc taatagtcct ttagatataa tcaagttgaa
     4921 catactgggc gagtacaaga tcccttactt ccacaacata ggattgtaaa taaagtgtag
     4981 tggcttgcaa agcaagtgga taagcttaaa attttaagta caaatcaatc catcacttgg
     5041 cataactcaa atctttgtgc aaacaaagtt acacgttact tataactacc atgtactgac
     5101 agtatgttca cctcaattac taaaaataaa gaaatgaaca agcatcagct caactacatt
     5161 tctattttta attcagttcg gcatttaaca taaaatctct tatacgaagc ccaggttaat
     5221 tctgggcttt ttgttcaatc tcatcattgg ccgagaacat acttggattc gtaagcctga
     5281 tattttcctg acaacttcca cacagcatca atcctgcaaa aagttgtaca ttttgtctat
     5341 tttcacaaag cgtacatggc tttgaaagct gaataatatt atctgacact actttaccct
     5401 cttatagtta tcatctgcat atgaataacc tttagcttgt atcattctaa cctcatcttt
     5461 agaagcgcca tttttcatta agagccacaa catcatgaaa tatagtccag aaaagtcttc
     5521 atagtatttt tcagaaaaat tgttatcttc ctcaaaatca tctattcgct tttctaatcg
     5581 attcaccaga tcctcaatac gatcggcttg ctgtttaaca gcaatagatt gaaaatcatt
     5641 ggtcaaaatt ttactgaata atttactggt tctgattcct tctgaattag ccaattgatc
     5701 gtagaattct gctacttgtg gatctaacct gactgcataa gttttgactt tttcgcccat
     5761 aaattacacc tcttattaaa attagatttt gtacaaaatt aaatatatat aattcaacta
     5821 attaaataaa aaataataat tagattacgt acaaacttat ttgtacagaa ttaatttatt
     5881 ctaaaacaaa aacttattta aatataatgc tttttttatg tacaatcatg agtacatatt
     5941 ttttcttaaa tttatcaata tcttatctaa aaaaagtgtt gttttgatgt acaaccatga
     6001 gcacagcata aaaaatagat aattcaatca cttattctaa aaaaagacca tttttctgta
     6061 cacgtttctg agaccctaaa aaatcgctga aatccttatc ctgtaaggct ttgaggggtg
     6121 tcatcgttag atgcgtggtg tgtgacaaaa aaatcccggc atgtgccgga tcttggattg
     6181 gaaaattggc taaagtgacg tagggccggt gcttggtttt gcatggaaaa aagtatttat
     6241 ttccttgttt agaaaaacgt aaaaaatcaa ttttttgtcc attcatccag gttaaaaatt
     6301 tcaacccaaa actttaatta tgaaaagctt catagaacgc gttcaaatgc gatttaagag
     6361 cctttaccta gaaaacatag atctcatagt gaaaaacaca aaacagctca aaaaacgcaa
     6421 atgagagcga aataaagagg tattttgact ttagatagat gcatagagcg agtgtctacg
     6481 agcgaactat caaaatttgc gcctagaccc tctgaaaaac atttttttgt cctctttagc
     6541 ctaagaaagc gtaagtttcg tgcagaaatt tgctcctgga tcgagcgtag cgagtaaaaa
     6601 agttttatga gcgaagcgaa ttccaagttt cttttgcttt tttttaaagt cacgccagta
     6661 ttaaccaaaa aattgcccca acgaactgag cgaaagcgaa gttcaataga gtttgagcga
     6721 agcgaaaacc aagggcaatt tttcattccc tgggctttta attattttaa agtttttaaa
     6781 tacttttaaa tggcttgaaa gccttatgaa taaagggttt tagctcttat atgtccacgt
     6841 ttaccttgca atatgtccac gtttaccttg caatatgtcc acgtttacct tgcaatatgt
     6901 ccacgtttac cttgcattag tacacaaata atattaacgt gtacttatac acaataaaaa
     6961 atagtggcta tgagagattt agttgtaaag gacaatgcct taatcaacgc aagctataac
     7021 ttagacttag tagaacaacg tttaatttta ttggctattg ttgaagcaag ggaaagtggg
     7081 aaagggatta atgcaaatga tccattagaa gttcatgcag atagttatat caatcaattt
     7141 ggtgtacacc gtaatacagc ttatcaagcc ttaaaagatg cttgtaagga tttattcgcg
     7201 cgtcaattta gctatcaaga gaaaaaagct aatgggaata tccgaaatgt tatgagtcgt
     7261 tgggtatctc aaattgctta taacgacaat gaagcaactg tagacttaat atttgcacct
     7321 gctgttgttc ccttcataac ccgactggaa gaacaattta ctaaatatga attacagcaa
     7381 gttagtagtc ttagtagcgc ttatgccatt cgcttatatg agcttctaat tcagtggcga
     7441 agcactggta aaaccccaac catagaacta caagaattta gaaagaagtt aggcgttctt
     7501 gataatgaat atttacggat ggctcattta aaagagcgtg ttttagagct ttcaattaaa
     7561 caaataaatg agcatacgga tataactgta aaatatgaac agcataaaag aggacgttct
     7621 atttcaggat tttcttttac ctttaaacag aagaagaagg atagcccatc aatagaaaga
     7681 gatccgaaca ctttggagct tttttcaaag atgaccgatg ctcaacggca tatgtttgca
     7741 aataaacttt cagaactccc tgaaatgggt cgctattcac aaggaacaga aagctaccaa
     7801 cagtttgctg tacgtattgc tgagatgcta caagatcccg ctcaattcaa agagctatac
     7861 ccatacctaa aaaaagtggg atacatgcca tcaaataaaa aggacaccgt aaatggctaa
     7921 gttatcacta agtgaagtat ctaaaaaatt tcatgtggat agatcaacca tttacagagc
     7981 tgtacgtaat ggacgtttat cacgctccag tgatggacaa ttcgatctag cagaggtcat
     8041 acgatgcttt ggagaacctg agcaaacatc tcaaaaaatt gaatcatcta agcaagaagg
     8101 tgatgaatct acaaaaaaac ttattgccca tttagaaaat gaagtcaaaa aataccaaga
     8161 acgtgaagaa cggttaatgc aacaaattga ccgtatgcaa acactcattg agctgaaaag
     8221 tgttgcacct gccacagcag caccacacca agatgctacg gcatgcgaca ccaagatgcc
     8281 acagcatgcg acaacacaac aagacactga taacaaaaag aataatgaat taaatattgc
     8341 agaaaatgta gcagtgccac agcaagaaac tacggcatac cacacccaaa cgctacagca
     8401 tgccacgttg caaagtgtgg cagtgccaca acacaaaaaa cgtggtttat ttggccgtgt
     8461 gctgaatgcc gtctttgata atgactgagc aataagggtg aaagatcatg ccgaaactga
     8521 aagacattgc cctgggaatt attgtagctc cgctgctgat cccgatcatg ctgattgcat
     8581 cgtaccagga taaaaaggcg ctgaagaaag agctggatga atgccaaaaa gaaaaagacc
     8641 aggcatcctg attattcaat tgagctaatc aaaagtgtgg aacattgatg aaataatagc
     8701 gtggaacgtg aaaagtcata aaaaaagccc g
//
