LOCUS       NZ_CP104021            27068 bp    DNA     circular CON 25-SEP-2023
DEFINITION  Staphylococcus aureus strain 0831 plasmid unnamed, complete
            sequence.
ACCESSION   NZ_CP104021
VERSION     NZ_CP104021.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN30633109
            Assembly: GCF_025152705.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27068)
  AUTHORS   Bollar,G.E., Keith,J.D., Oden,A.M., Kiedrowski,M.R. and Birket,S.E.
  TITLE     Acute infection with a tobramycin-induced small colony variant of
            Staphylococcus aureus causes increased inflammation in the cystic
            fibrosis rat lung
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27068)
  AUTHORS   Bollar,G.E. and Birket,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-SEP-2022) Medicine, University of Alabama at
            Birmingham, 1720 University Blvd, Birmingham, AL 35294, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Assembly Name                     :: UAB_Saureus_0831
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 500.0x
            Sequencing Technology :: Illumina NextSeq; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/25/2023 02:48:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,928
            CDSs (total)                      :: 2,846
            Genes (coding)                    :: 2,761
            CDSs (with protein)               :: 2,761
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 85
            CDSs (without protein)            :: 85
            Pseudo Genes (ambiguous residues) :: 0 of 85
            Pseudo Genes (frameshifted)       :: 45 of 85
            Pseudo Genes (incomplete)         :: 45 of 85
            Pseudo Genes (internal stop)      :: 17 of 85
            Pseudo Genes (multiple problems)  :: 21 of 85
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP104021.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27068
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="0831"
                     /isolation_source="lung"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed"
                     /geo_loc_name="USA: Birmingham, AL"
                     /collection_date="2017-08-31"
     gene            join(26217..27068,1..120)
                     /locus_tag="N0J69_RS14470"
     CDS             join(26217..27068,1..120)
                     /locus_tag="N0J69_RS14470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_260050996.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFKEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            complement(292..384)
                     /locus_tag="N0J69_RS14475"
     CDS             complement(292..384)
                     /locus_tag="N0J69_RS14475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(541..888)
                     /locus_tag="N0J69_RS14480"
     CDS             complement(541..888)
                     /locus_tag="N0J69_RS14480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(907..1524)
                     /gene="cadD"
                     /locus_tag="N0J69_RS14485"
     ARG             complement(911..1524)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(2640..2834)
                     /locus_tag="N0J69_RS14490"
     CDS             complement(2640..2834)
                     /locus_tag="N0J69_RS14490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            2944..3636
                     /locus_tag="N0J69_RS14495"
     CDS             2944..3636
                     /locus_tag="N0J69_RS14495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            complement(3804..3953)
                     /locus_tag="N0J69_RS14500"
     CDS             complement(3804..3953)
                     /locus_tag="N0J69_RS14500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(4500..>4789)
                     /locus_tag="N0J69_RS14505"
                     /pseudo=""
     CDS             complement(4500..>4789)
                     /locus_tag="N0J69_RS14505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(4809..5792)
                     /locus_tag="N0J69_RS14510"
     CDS             complement(4809..5792)
                     /locus_tag="N0J69_RS14510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            6218..6961
                     /locus_tag="N0J69_RS14515"
     CDS             6218..6961
                     /locus_tag="N0J69_RS14515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(7188..7373)
                     /locus_tag="N0J69_RS14520"
     CDS             complement(7188..7373)
                     /locus_tag="N0J69_RS14520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(7378..7716)
                     /locus_tag="N0J69_RS14525"
     CDS             complement(7378..7716)
                     /locus_tag="N0J69_RS14525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            complement(7962..8570)
                     /locus_tag="N0J69_RS14530"
     CDS             complement(7962..8570)
                     /locus_tag="N0J69_RS14530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            complement(9056..9955)
                     /locus_tag="N0J69_RS14535"
     CDS             complement(9056..9955)
                     /locus_tag="N0J69_RS14535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            complement(10054..11520)
                     /gene="msr(A)"
                     /locus_tag="N0J69_RS14540"
     ARG             complement(10058..11520)
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            11994..12668
                     /locus_tag="N0J69_RS14545"
     CDS             11994..12668
                     /locus_tag="N0J69_RS14545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            <12726..13103
                     /locus_tag="N0J69_RS14550"
                     /pseudo=""
     CDS             <12726..13103
                     /locus_tag="N0J69_RS14550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            13100..13981
                     /locus_tag="N0J69_RS14555"
                     /pseudo=""
     CDS             13100..13981
                     /locus_tag="N0J69_RS14555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            14097..15026
                     /locus_tag="N0J69_RS14560"
     CDS             14097..15026
                     /locus_tag="N0J69_RS14560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            15019..15756
                     /locus_tag="N0J69_RS14565"
     CDS             15019..15756
                     /locus_tag="N0J69_RS14565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            15770..>15946
                     /locus_tag="N0J69_RS14570"
                     /pseudo=""
     CDS             15770..>15946
                     /locus_tag="N0J69_RS14570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            16003..16677
                     /locus_tag="N0J69_RS14575"
     CDS             16003..16677
                     /locus_tag="N0J69_RS14575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            <16818..17453
                     /locus_tag="N0J69_RS14580"
                     /pseudo=""
     CDS             <16818..17453
                     /locus_tag="N0J69_RS14580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            17450..17980
                     /gene="sat4"
                     /locus_tag="N0J69_RS14585"
     ARG             17451..17977
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            18073..18867
                     /gene="aph(3')-IIIa"
                     /locus_tag="N0J69_RS14590"
     ARG             18074..18864
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            19143..19714
                     /locus_tag="N0J69_RS14595"
                     /pseudo=""
     CDS             19143..19714
                     /locus_tag="N0J69_RS14595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(19883..20557)
                     /locus_tag="N0J69_RS14600"
     CDS             complement(19883..20557)
                     /locus_tag="N0J69_RS14600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            20819..21004
                     /locus_tag="N0J69_RS14605"
     CDS             20819..21004
                     /locus_tag="N0J69_RS14605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            complement(21227..21805)
                     /locus_tag="N0J69_RS14610"
     CDS             complement(21227..21805)
                     /locus_tag="N0J69_RS14610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(22069..22449)
                     /gene="blaI"
                     /locus_tag="N0J69_RS14615"
     ARG             complement(22073..22449)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            complement(22439..24196)
                     /gene="blaR1"
                     /locus_tag="N0J69_RS14620"
     ARG             complement(22443..24196)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            24303..25148
                     /gene="blaZ"
                     /locus_tag="N0J69_RS14625"
     ARG             24304..25145
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(25674..26093)
                     /locus_tag="N0J69_RS14630"
     CDS             complement(25674..26093)
                     /locus_tag="N0J69_RS14630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     ARG             complement(9060..9955)
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(10055..11520)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             complement(9057..9955)
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             17463..17980
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             24304..25148
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     ARG             16855..17156
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     Typing          complement(4297..4444)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(4503..4678)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.697"
                     /coverage="94.0"
                     /evalue="1.04e-65"
     Typing          complement(4810..5792)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          6219..6961
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 aatgaatgga atataggaaa ttcacttcta tacaatgaaa ttggatttaa agaattctat
       61 aaaacgatag atcagctttt aaaaggacaa catttaggaa gaactatttt aaaagtataa
      121 gtgtgagtat tcattaatac atttactatt aattcaatca ttttgcattt ctctactaac
      181 cagtgttata atttatataa cgaaaatgat taacaattaa tgcaccaatc cccacactat
      241 tgcagtagtg tggggatttt ttcgatgctg gcttataaag tcgcctatta attatttgtt
      301 gcgtttacta agccaataag tataatacgc aacagcacag ccactgatga ctggtgctat
      361 gatgtgaacg aaaatgatta gcaaagtaat gcacctcctc tcttcgtcaa ttgacgcctg
      421 agagataggc gactctatta ttataccatc tgtgaatata caagcatatc tacttccgat
      481 aagtcgtctt atgttatata actttgtttt ttatagtatc aagacaagaa gaaactcgtt
      541 tcaaaaaccc tcatgatttt tagagaaaaa ctctcttatt tcatcgtctt taataaaata
      601 atatgccatc tttccatctt tataaaaatc aagtacctca tttttatata aaagccttaa
      661 atgatgtgaa gttgaagcaa cactcatttt caatatcaaa gaaatatcac aaacacacaa
      721 ctcatcttct ttaatcaaag ataatatgat tttcaatttc ttctcatcac aaattttttc
      781 taaaatgtta agtaatttct tagatttatc atcttctaaa aaacttaaag cattgttaac
      841 tttatcctca tgtacacaga tcacatcaca agtattttca taactcatat aaaatcacac
      901 cctaaattaa aatataaatc ctaaaattgt ttgaatagtg tcattttcaa taataataaa
      961 taaacctaaa gctatataaa taatagccat aatccaacga ctaaatttct caacaatttc
     1021 tccaattcct ggaatattag ctaatttttg tgcagtaaac accaagaaga aaattaaaat
     1081 taaaaagaca aacagagtaa gtaataaatt agtaacactt aatgtcacaa aatacggaac
     1141 aaataaacca atattatcgg cgccacaact tgctatcgta acaattgcaa ccgtaccaac
     1201 taatttagac aatccttttt cattcaattc ttttttagct ctcttttctc cttcacaatc
     1261 atcataaata gccactttaa ttccaagata aattggtatt aaacccaata aacctaatat
     1321 ccacttttct ggaacataat ttaatacaaa agctaaaaac aaactaacta atattaaaat
     1381 aatagaccct aaatattgac caacataaat atctctatat tcttttctag tctttgctct
     1441 agcaaaaaat attaataaaa ttactaataa atcaactgct gtagcaatat aaagaacagc
     1501 agcagcaaca accgtttgaa tcataataca cctcattcaa aaatattttt gaatgtatta
     1561 taacttatat ttttaaataa tcataggtgc tttattccaa ttgctttatt gacgttgagc
     1621 ctcggaaccc ttaacaatcc caaaacttgt cgaatggtcg gcttaatagc tcacgctatg
     1681 ccgacattcg tctgcaagtt tagttaaggg ttcttctcaa catcaataaa ttttttcggc
     1741 ataaatgcgt gtctatgcgt agacatggag acacttcaga attatggagt gattacatga
     1801 gtttaactat ttttctttat tcagttttag gaagtttatt agcaaattat atctacgaaa
     1861 aatcttcaaa ataaataact ttttcggttc tactttgtac actttatcta cctggtagac
     1921 ctaattgtta ttgctttaca ggtctaaaat tcgtcgttat aatctagtta aatcccgtaa
     1981 gggcgcactt atacgtcgga taaatcgaca tgtgcaaaaa cgtaatcgac cttcgtcgat
     2041 ttttttattt caaaattaaa gaaacggctt gagatattcc gagcagttat aaaaattaat
     2101 ttgcgttgaa tattgctact acattcttga aaaagtgatg tagatttata gcccataact
     2161 tttttgaatt acatcgacga tacggcgtcg aaagaaaaat aaatagaccg tatgaaagaa
     2221 aaagctacct cactttatct ggggtagctt ttatttttta tgcccttatt ttgaatttta
     2281 agagggcatt ttaaagattt aggggtgatt catatagttt tatatctaaa acttatatat
     2341 gcttttaaaa cgcaaatatg agccaaataa atatatgcta ttttcaaaaa caaaaatttg
     2401 agcaaaaaca ataactattt ttagacactg cccatttaca tgcaaattaa aaattagcat
     2461 aaaattcttt aaaacttccc cacgtttttc taaattcctg tagggcgttt ttatcaaaaa
     2521 tcaagacaag aagaaactcg ttcacactcg tttcaaaaaa acaagaaatc taatctatac
     2581 acctaccgtt ttccaacccc ctcaaagcat acaaattaaa aacaaaatta ttcataatct
     2641 tactttcttt taacaaaaac ataaaaacca taaatagaca aattaactat caaaggcaat
     2701 aaacagtata aaaaaaccac gaataaatct tcatcaacat ctaaaataaa aaagaataaa
     2761 acaattaaca aaatactaat taacaaacct aaaagtggca aactttttat atatttttct
     2821 aaattttcat tcataaaata gactcctttc aaaaatatgt ttataaatat attaaaataa
     2881 atattgattt tataaagcgc ttacttatac aattaaaata tcttattatc ttggaggtat
     2941 caaatgaaaa ttataaaatt attttcaata atttccttgt tcctactggt atttagcgcg
     3001 aatttttcta atgcttacgc aaatgaagaa caaaaaagtt ctttactaga aaatcaaaaa
     3061 gaaaaattga aaagcaaaaa catcgaagta tcacaaatga ccaagaaaga aataagtttt
     3121 ctagaacaat tgcaaaataa aaatgaagat atgcaaaaat tcgaaaagca aatgaaaaaa
     3181 gaaggattta aaaaaataaa gctagaagac aaaaattcta aattaaaata tctagctaca
     3241 gaagcaaatg ataaaaatgc atatggctac atagctaata acgcttataa aaatgaaaaa
     3301 acaaaagaaa ttgtagtttc tgaaacaata tatgataact acaacaaaaa aatcacaaaa
     3361 ttcattgccg aaaaaagaag tatgactgaa aacaaagagg gaaaaatact tattaacaaa
     3421 aattacgttg aatataaggc tgaaaaagtt gataaaaaca gaccggtaac atatgcagga
     3481 ttcaaatgga acggcaaagc attcgcttgt agtatggctg gactttatgc atgtgctcac
     3541 tactgtggag tatgggcaat cgtaaatcca atagccggcg gtgtatgtga agcagtttgc
     3601 ggaactgcat ttgcagctgg atgctctgta ggttgatttt attccaattg ttttattgac
     3661 gttgagcctc ggaaccctta acaatcccaa aacttgtcga atggtcggct taatagctca
     3721 cgctatgccg acattcgtct gcaagtttag ttaagggttc ttctcaacat caataaattt
     3781 tttcggcata aatacgatgt tccttattta tcctcataaa aaacaatagc tgaaatatat
     3841 aaccaattac tgtgtgtttg aatttctaat acatgaatat cattctttaa aaacctatta
     3901 acttgtttat ctaattgacg atgagtaaaa gtagcgaaag ttttaatctt catgatatct
     3961 ctccttttat aaaaatagca atccttatta caatattaaa cacttttatt ttggatttta
     4021 agaggcattt tgaagactta gaggcaaatc atataggttt tgtacttaaa aatctataca
     4081 gtctcttaaa acgcaaatat gagccaaata aatatatgct aatttcacaa acaaaaattt
     4141 cagcaaaatc agtgactaat tttttagata ctgcccattt acatgcaaat ttaaaaatta
     4201 gcataaaata ctttaaaact tccccatgtt tttctaaatt cctgcagggc ttttcttatc
     4261 aaaaacttag aaattttaat ttaactctaa aatctccgta agagcataag ggaaatttgc
     4321 tatcattcaa aaatgataga tctggcaagg ccagacattc caagggtttt aagttatttt
     4381 aaagtgatat catacaaagc tgtagtgtca cacttttgtg acactacata cagcatttgt
     4441 cacaaaaata agacagcact tttttacaga aaaacaataa aaaaagacat cagttatcac
     4501 taatgtctta aataataatt ttgcttttcg aaattccaaa ttgcggtaat tgaatgtgct
     4561 ttttttcttc gtctgtcgtt ttatcttcat cacttgtatt aatcaaatta ccatcttcgg
     4621 catcgtctaa gtttaaaatt ttatgctttt gtttaagcaa tccaccataa cttaacatac
     4681 gttttcgata caaacctttt tctaaatcac ttacaatttc ttgatttttt tcgtcgtcat
     4741 cagttaaaaa gtcagatgat ttaacggaat attttgatgt ctcttcgagt gttataaaat
     4801 catttgaatt attgattaaa gatattatat tgtttcatgt ttttacggcg catataaagg
     4861 gcatgtgttt cttcaagttc agttagaatt gtttgcatta aataagcttg cattgacttg
     4921 attgtttcct tttggccttt aactccccta tcatgtatag cttttttaag tctttttaaa
     4981 gaagttaata tttcatcctc aatgtcctct aacatgtaat gcatatcttc atgccttgaa
     5041 ttaaatgatt tttttgcttt aagaataaca gcctttatga tttctaaatc tctataatca
     5101 tattttaata aataattagt tagttgttct gggaattctt gcaatagcat ttctttatca
     5161 tcaaaattat gtgtaaattg atttgaatga tttgaatgat tactaatttc atttttgtac
     5221 tttatatcat tcaagtcatt catatcatta ttctcagtat cattaaagtc aatgtcatta
     5281 aagtcagtat cattagtgtt cgattttcga acttctggac gttcgatttt cgaacttctg
     5341 gacgttcgat tttcgaactt ctggacgttc gattttcgaa cttccttctc gccgtaaggt
     5401 tcaacatcgt tttcttcttt ttctattttg taaatatcac gttctgtgac aataggtttc
     5461 attaaatata gaatatttgg tttatttaaa ccacgtcgtt tttgaatgag tagaccatcg
     5521 ttttctaacc ctttttttat ttttgttaac ttttcttttt tacaatttaa gatttccatt
     5581 agcttttcat ttgaataaac aaagtaaatg ttaccatctt catcaaccca gctattttta
     5641 atagataaat ttaagcgatc acgtaagata gcataggcta ttttcatatc attagttaga
     5701 tttttataat tttcactggt aaagaatact ttagggattt gataaaatct ttctttgtaa
     5761 ttttcttgca ctgtaaaata ttgattttgc atgacaaaaa acctctttcc atattttagt
     5821 ttggtaagag gtaataaaac gtttttattt agctttacat ttatttaatg atttaggtgc
     5881 ttgcactaag atattattca ttatataata caagtatcga aaattatata aataaacagt
     5941 ttctaaacgt tttattacca aaccccgact attaccagta gttggggttt ttgttatatt
     6001 aagtttatta tagcacttta aataaactta taaaagggaa aatatagctt tatcaagggt
     6061 ttataaaccc ttgataaata tcataaacct ttcataaacc cttgataaaa aggttgatgg
     6121 atgtttattt ttatttatta atcactttat tattaagcat tataagctta taatatttta
     6181 tcaagggttt ataaacattt tataaagggt tgatgatatg aaaagtgtga aaaagttgag
     6241 tgaagaatta ggggttagta agcaaacgat ttttaataat attaagcgat tgaatataga
     6301 gacaataaaa caggaaaaca cttcgtttat taaagaagat accgatatag aaaaaatcat
     6361 tcaaagagta aatgaaaata aaaagaaata tggttttgaa agtactactg aagacaaaca
     6421 aaaaaaaggg tcggataata ttaattttga atcgaaaagc gatgctcaaa tagtagaaat
     6481 ccttaaaaat cagattgata ctttaaataa tcaaattgaa aaacaagaaa gtcgtcatga
     6541 aacaacaatt gaattttaca gaaaagagtt gcaagaaaga tcaaaattgc ttgaaaatca
     6601 gcaagttctg gcattagaga gtaataaaaa gattcaaaaa ttagaaaatc aattagaaaa
     6661 agaaaaacac cttaattatc cctttgatac atctactaac actagacaaa acgttgatgc
     6721 acaagaaaaa acatatacta ctaatcctgt aaatattaac agagatcagg aagaaactaa
     6781 agaaacagag attcaatata aggatatatc tggaagtcaa agcgacgaaa gtacacaagg
     6841 tgaagaagca aaaaaagaag acgttccagc taatctaaat gacaatgata gtgatataga
     6901 agaaaagagt gaagaaacgg aacctaaaaa ggggttttgg agtcgtttgt ttggtagcta
     6961 aaataattga ttaggcacta aaagttataa aattttagtg tcttttatat agtgagaact
     7021 tctggtaatc atcgattatg taaactaaag tatttcaaat aattaactgt attaatactc
     7081 tcatcatgat tgcgttataa acgttcgtta ttgagacaaa atttaatagt actactacac
     7141 aaaaagagag tgcgaattcg cactctcttt ttgtgataaa tgaatggtta agaaaataat
     7201 tcatccacag ttgtatcaaa caatcttgcc aacttaaatg ctaatgtcaa tgtaggatca
     7261 tatttattgt tttctattgc attaatagtt tgcctagaca cttttaattc tttacttaaa
     7321 gtttcttgag aaattccttt ttgttttcta tattctctaa ttctattttt cattaattta
     7381 acctttagat gtatattttt tatttgtagt atagtaatta aacagcataa gaaatagtgc
     7441 tacaattata aagaaaattt ctggatattg agaaaaccaa gatccttcaa tacttggtga
     7501 caaacctgta aatttaagca ctagtgtaaa taacatacaa tatacaatcc aaataaaact
     7561 tttagccagt atttcaataa acattttacg ttgtctttca tcgtatcgat cttgttgtcc
     7621 ttttttatct aatgtttctg aaggtaaata tttgttagtt atagccgtcc ataaacaaga
     7681 aaaaattaaa ataataataa aaggaattaa attcattata acacctcata aatgtaaaaa
     7741 gtatttgaca tttatgagtg taaatatttt tgatacaaat gtcaaatact ttttacatta
     7801 taatatattt taaaacacct tattagtaaa acaattacta tatagaaagc tgcgaactcg
     7861 tactcttttt tcttgtataa ttattaaaat ctcaattcaa taatatgtta tggaatttga
     7921 gacactgtga gagacgctca tttgcattga caatcaattt atcaagataa tcccttatca
     7981 tgtttaattc tataaactgt ttgtcttgtg atattaactt ctttcgcaat cttactaatc
     8041 gctttgcctt cttctaacat ttccaccacg cgatgataaa taacacgttt ctgtgggtct
     8101 ttagcatttg gtgaataaag taaagggcgc cctttatata cgcctttttc cttcgcaact
     8161 tgaatccctt gcgcttgtcg acgtttactt tcatttctct cttgttctga aaccattgct
     8221 aatatttgaa tgattaaatc tttcataaac ttatccagta atggattgcc aattacttca
     8281 ttcatcatag gtaagctggt aatcattaac tgaacgtctt tttcttttaa ataattcaca
     8341 gtttcaataa tttcatcata gttacgtcct aaacgatcaa tagattccac aacgaatcga
     8401 tctcccattc tgacaaaatt gagtgcttct tgaaatacag gtctattttc cactgacttt
     8461 cccgactgtt tctctgtaaa gattttctcc acaccaaacg tctttaaatt atccaattgt
     8521 ctttctaaat tttgatctat cgatgatact ctcgcataac ctataatcat tcatcttcac
     8581 tccataataa atatacaccc taatcatacg ttttaattgt tataatttca acaattcttt
     8641 ttgtatggtt agggtgtact caaagtgtac atatctataa ttaaaactta ctaaaaataa
     8701 atatagattt tttctttgta acagaaccgt tcatttgaag gtcatctcta tcataaatat
     8761 ttaaattaac taaaaatttt aatcatctgt ttaatactta tgaaatgtat ttacggtagg
     8821 tattaaaatt gatgaaattt atataagtgc tttcaatgaa aatgaccgtt tatttatcct
     8881 cctgatttaa ggagttagaa atttcgaaaa cgattctttc catttgttgc atttgttcca
     8941 tgtccagata tttaatacat tatagaaaac caaagaccat cactaattaa acgcagtttt
     9001 aaaatttcat caggattgcc ttcgtcttta aaatgggcct cttttaatat aagttctact
     9061 ctttcatacc taactctttc aatgccatcg tttcatacgc cgattctcct gattccatag
     9121 caaactcagc gataaacatt gggaatactg cattgagttc tattatatgc tctttcattc
     9181 gtggccatat ttcacctcca gctttaccgt atgctgttat aagttgctct aatccttcgt
     9241 cgtcgaatac acgatggtgt cctataaagt ccattgatgg gtcggagtgg gttgcttcag
     9301 tccagtctat gagacctgtg acgtttgctt ggttatctac cattatatgt cctggatgta
     9361 agtccccatg tatcatggtc gcatgtcgag gccatagttc gtcgttttct aaccattgtt
     9421 tccatctgtt ccataattca tctgatacgc cataagtttc tttaacttta ttcattcttc
     9481 tttgaaagtc attttttatt tcttgtatgg ttttgatatt tatatgctga acgttaatgt
     9541 tttcttctgg tatgttgtgt aaatctacga gtgtttcagc taatgtgtta ataaagtttt
     9601 ctggtaatgg tttgtgttca atttcccata cataattttg tatttctgga tctattgtgg
     9661 ctgcgggttt acctgtaagt tttgggtaag caataaggtc ttttgcatgt actttccact
     9721 tcggtatttc aaatgaaaca ttcttctgta agaagtctac cgtttgtttt tcgggttttg
     9781 ttcgtttata aacgtcaggt cttcttggta gtctcaaaac ccattctact ccatgtttat
     9841 cttttccaaa tgcaacttga aaatcaagtc ccgattcatt caatgagatt gtttgaggtt
     9901 ggatgtgtaa ttgatatttt tctgcacatt taataatttc attatgtcga gtcattttat
     9961 tggatcctta tttctattat atttttcttg tgaacgtatt ttttatattg atataaatga
    10021 acctaatatt caatataaat tagtgtatag tttttaagtt atatcatgaa gagattgtcc
    10081 tgttaattcc cattttttat ctgatacatg tttaacaaac cttgtatcat gtgatgtaaa
    10141 caaaatgatt ccaggatatt tattcataaa catttctaat gcttctaatg ttttaatatc
    10201 taaaaaatta gttggttcat ccaaaattaa catattcgct ttcgttgaaa ataatactgc
    10261 taacgataat ttcgttcttt ccccaccact caaaacatta caagaacgat caagtgcttc
    10321 atttaaaccc aagttattta aaatagctct actgaatgat tctgatgaat ccgtttcatc
    10381 cattaaatat tgcaataatg aaacgtcacg catgtcttca taagcaagtt gacgatagta
    10441 tgccatttgc actttaggag aacaatcaat tccctctatt tggtggtaaa tagcttcaag
    10501 taaagttgtc ttacctacac catttgcacc tacgagcgct atatttttgc catatggtat
    10561 ttggaatcgt acttgtgtta gcagtttttg acttccttta accaatgtta gattttgtgc
    10621 aatgattgga taattattat ggatatcata aattttattt tgtgggaaat tgaattcatg
    10681 ataactttgt ggtttttcaa cttcttccaa atgttccatt cttttttcaa tatgcttagc
    10741 ttgtttttga gcagccttct caaccgtgcc tttttgtttt gatgcactta aacgatctgg
    10801 tgctatactt ttgttttttt gttttgatga tgcttgtgcc atttgttgcg cttgatttcg
    10861 tttagcttta ctggcttggg acaatctttg tttttcactt atatactgtt catattgacg
    10921 ttgttgttct aactgttctt gttcatattg attttgatac tgtgtgtaat tacctttaaa
    10981 cactcttatt gtgccatctt cttgtatatc ccaaattgtg tcagcaattt ggtctataag
    11041 tgctctatca tgacttacta taattaaagt accatagtaa tattttaaaa tatttttcag
    11101 ataatcttta ccaattttat ccaagtgatt tgtaggttca tctaaaagta atatcggact
    11161 ataatttgat atgacattag ctaatttata ttttgctttt tcaccaccac tcatactgtc
    11221 ggttgtatgc ataggtatat ggagttcact cattaaacta ccgtctaacg tgttaaaatc
    11281 attttccaca tccatgttaa gctgttcaaa atattgaatt tcgccaaccg tttcaactgt
    11341 tccagattct ggttttgttt tttgagcaat catatttagt aatgtggttt tgccagtacc
    11401 attaccccca ataagtgcta ttttttcaaa ttggtaagcg taaagatgac cgatgttaag
    11461 tgatcgtaaa tctgtcaatt tatgattgat ttggttaaat ttaattgtat attgttccat
    11521 atttatacac tccttgtata tttaaaggac gtgtacgcaa aaaaatgaga caggctactc
    11581 ccgtctcatt cacattacac tttcaaacac ttaaaaattt attatgatgt tttagtattt
    11641 gaaagcgttt attattccta tcgaaggata aaaaatgaca taagtcatcc tatgagtgtg
    11701 tattgcggac aagccttttt gaattaattt agttttgtat tcaaaaaggt ttatttgagt
    11761 ctcatagaag ctgtcatttt aatcctcctt catcgataaa atagtaatgt taatataaca
    11821 ttttgttggt ttttttacaa tatatctcta agtagaaaga ttatataaca aaagtataaa
    11881 aatacaattt tagattgatt atacatctcc ttaatttaga gtgtactcat aaaatacggt
    11941 tctgttgcaa agttgaattt ataatataat tttaacaaaa aggagtcttc tgtatgaact
    12001 atttcagata taaacaattt aacaaggatg ttatcactgt agccgttggc tactatctaa
    12061 gatatgcatt gagctatcgt gatatatctg aaatattaag agaacgtggt gtaaacgttc
    12121 atcattcaac gatctaccgt tgggttcaag aatatgcccc aattttatat caaatttgga
    12181 agaaaaagca taaaaaagct tattacaaat ggcgtattga tgagacgtat atcaaaataa
    12241 aaggaaaatg gagctattta tatcgtgcca ttgatacaga gggacataca ttagatattt
    12301 ggttgcgtaa gcaacgagat aatcattcag catatgcgtt tatcaaacgt ctcattaaac
    12361 aatttggtaa gcctcaaaag gtagttacag atcaggcacc ttcaacgaag gcagcaatgg
    12421 ctaaaataat taaagctttt aaacttaaac ctgactgtca ttgtacatcg aaatatctga
    12481 ataacctcat tgagcaagat caccgtcata ttaaagtaag aaagacaaga tatcaaagta
    12541 tcaatacggc aaagaatact ttaaaaggta ttgaatgtat ttacgctcta tataaaaaga
    12601 accgtaggtc tcttcagatc tacggatttt ccccatgcca cgaaattagc atcatgctag
    12661 caagttaaac gaacactgac atgatatatt agtgattagc tatatttttt actttgcaac
    12721 agaaccagcc atttaatatg actgttacaa ttactaagat tcaagcacta ttacgccgca
    12781 cgtatgattt caccactcaa gttaataatt taacagtaga tgattgcgag ttactacttg
    12841 atgcagcaaa gcttaaattt aatgaagaaa ccatagacct gacacacact gaattgcaaa
    12901 tcatgcatag cttattccag aacaagggca aattcgtcag tcgtaatgcg ttaatcgaaa
    12961 aatgctggga atcagaacac ttcattgatg acaatacgct tgctgtcaac attacacgtt
    13021 tacgcaaaaa gctacaaaaa ctaggactta cagattttat cgaaacgaag aaaaatgtcg
    13081 gatatcgtgt aggtgacgta tgaatttctt gaaatcaatc caacgtgaaa tttatattgt
    13141 catccttact tgtgctttat tctactttat attattcatg tataatgtgc cgatgcaagc
    13201 atatatgatt ggtctaggta ttgtattgtt tgtttcaatg atttactggg gtatccatta
    13261 catgaacttt aaaaaagaat aaacactaca ggaacagaac gaagatttaa gaatcgaaaa
    13321 ccataaactt cgtaatgact ttattaacta ccaaagtgag ttagagtcat attttttaat
    13381 gtgggtgcat caaatcaaga caccgattac agcatcaaag ttactgcttg aagatcctga
    13441 tgaacacgtg atttctaacg tgcgtaatga agtcttacaa attgataatt acacgaatct
    13501 tgcactgaac tatttgaaac tcatgaacca aaagacatac atggtcttta tggaagtgag
    13561 tgtagatgaa ttaattcgac cactgattaa acgttatgcg atacagttta ttcatcatca
    13621 aacaaagttg cattatgaga aaagtgaagc ggttatatta acagatgcca aatgggcatc
    13681 aattatgatt gagcaaatat taaacaatgc attaaaatat gcacgtggca aagatgtgtg
    13741 gattacgttt gacgaaaata caaagaaatt atcaatccga gataacggta tcggcattaa
    13801 tgcgagtgat ttaccgaaaa tctttgataa aggtttctcg ggctataacg gtagaataag
    13861 tgagaaatca agcggtattg gtttatatat tgtcagcaca atctcaaagc gcttaggcca
    13921 taaagtaagt gctacatcta cattaaacga tggttcaata ttcaccattc aatttaaata
    13981 actccaatct ttcatttttg taagattagc ggctgttttt gtaagaatag ataaaggcag
    14041 ccttttctaa tcgcgcgtaa gataaaggta acaacaaact aagaaaggtg ccagaggtga
    14101 aaaatttgaa taatataatt gaaataaata acttaacaaa gcaatatgga agtcagatag
    14161 cagttaataa tttgagtata actgttgaaa gtggacaaat ttatggtttt ttaggaagaa
    14221 atggtgcagg caaaacaact actataagaa tgcttttagg cttaattaaa cctacgaaag
    14281 gtaatattaa aatatttgaa aaagagttcg aaagtaataa aactgaaatt ttaaaaaata
    14341 ttggtgctat ggttgaaacg ccaggttttt atagtaattt gacagctaaa gagaacttaa
    14401 ctataaatgc taaaatatta ggtatacaaa aagaaaatgc aattgaagaa gtgttagaaa
    14461 tagtaggact agcttctgaa aaagtaaaat tgtttaaaaa ttattcttta ggtatgaagc
    14521 aacgtttagg gattgcgaga gctttattgc acaatcccga attattgata cttgatgagc
    14581 cgacgaatgg attagatcct attggcataa aagaaattag aaagttgatt aaggatctgg
    14641 ctcaatctag aaatataacc attttaattt caagtcatat attgtcagaa atagagcagt
    14701 tagtagacaa ggtgggtatt attcataacg gagttttgtt agaagaaatt atgtatgaag
    14761 atttaaaaaa aaagaacaga caatttataa gtatatcagt atcagatgaa gaaaaagttg
    14821 catgtttgtt ggaaactaac ttcggaattt atgactataa aattaaagaa aatggcgaat
    14881 ttaaaattta ttcacatatt gatagacaac aagaaattaa tagattatta gtattaaaca
    14941 atattgatgt tttccagatg agagtgatag aagataatct agaaacttat ttcgaagact
    15001 tagtaggagg tggcacaatt ggataatcta ctccgtacag aatttattaa gttaaaaaga
    15061 tcatatatgt ttctaataag tattttaggt acatgcgtag caccttttat ggtggttgta
    15121 gcttctttta ttagtatgcg gacgaaagta ccgactccta atattgtatt taaacagtta
    15181 tttgaagaag tcagtttata tcatatgcta attattggac ctcctctata tggggttata
    15241 atagcctatt tgtttggaag agaatatata gaagatactt taaaaaactt attaattata
    15301 cctatatcta gagaaagttt tttagtaagt aaaataatat tattattctt gtggattcaa
    15361 acactatctg ttattgcatg gttgctaact ttaatgctag gtatgctatt gcattttcaa
    15421 gggttaagcc agagtttaat aattgattca ttctttacat ttgttattgg cggagtgtta
    15481 ttatggatat tatctccacc aataattatt ttgtcgatat attttaaaaa ttatgttccc
    15541 acaattgttt taaccataat aattactttg ataaatttaa tgactgctaa ttctgaacat
    15601 agaggattat ttccttgggc tgcagttgga gacatatcta gaggaacatt acctaatact
    15661 tatccatttc tattatcttt aattatcata attgttacat ctatattcag tgtaattata
    15721 ttattctcat actttaaaaa aactgatata agttaaaagg aggagaaaaa tgggttttat
    15781 agagcagatt aaagcattta ttttaggtgt agttgaaggg ttgacagaat ttgctccagt
    15841 atcatcaaca ggtcatatga ttattgttga tgatatgtgg ttaaacactg ctgacgattt
    15901 aggaagtgcg tctgcaacta cttttaaggt ggtaatacag ttaggaggtt ctgttgcaaa
    15961 gttgaattta taatataatt ttaacaaaaa ggagtcttct gtatgaacta tttcagatat
    16021 aaacaattta acaaggatgt tatcactgta gccgttggct actatctaag atatgcattg
    16081 agctatcgtg atatatctga aatattaaga gaacgtggtg taaacgttca tcattcaacg
    16141 atctaccgtt gggttcaaga atatgcccca attttatatc aaatttggaa gaaaaagcat
    16201 aaaaaagctt attacaaatg gcgtattgat gagacgtata tcaaaataaa aggaaaatgg
    16261 agctatttat atcgtgccat tgatacagag ggacatacat tagatatttg gttgcgtaag
    16321 caacgagata atcattcagc atatgcgttt atcaaacgtc tcattaaaca atttggtaaa
    16381 cctcaaaagg taattacaga tcaggcacct tcaacgaagg tagcaatggt taaagtaatt
    16441 aaagctttta aacttaaacc tgactgccat tgtacatcga aatatctgaa taacctcatt
    16501 gagcaagatc accgtcatat taaagtaaga aagacaaggt atcaaagtat caatacagca
    16561 aagaatactt taaaaggtat tgagtgtatt tacgctctat ataaaaagaa ccgcaggtct
    16621 cttcagatct acggattttc gccatgccac gaaattagca tcatgctagc aagttaaacg
    16681 aacactgaca tgatatatta gtgattagct atatttttta ctttgcaaca gaaccatcat
    16741 ttttattaaa atactctttt gtaaaatctt tctgctcttc aatgtattta atttctttac
    16801 ctctaaatct attatagcta tttgatgatt acaataaaat tgatcttacc ttattgccct
    16861 tggaagagtt agataattac ctaaagggcg ataaattaat aaaggttcta attgataaag
    16921 attgtagaat taaaagggac atagttccga ctgatataga ttatcatgta agaaagccaa
    16981 gcgcaaggga gtatgatgat tgctgcaatg aattttggaa tgtaacacct tatgttatta
    17041 aaggattgtg ccgtaaggaa attttatttg ctattgatca ttttaatcag attgttcgcc
    17101 atgagctgct gagaatgata tcatggaagg tcggcatcga aacaggcttt aaatgaagtg
    17161 taggcaagaa ctataagttt attgaaaggt atatatccga ggatttgtgg gagaaacttt
    17221 tgtccaccta ccggatggat tcctatgaaa acatatggga agcattattt ctatgccatc
    17281 aattgttcag ggcggtatcc ggtgaggtgg cggaaaggct tcattatgcc tatccggagt
    17341 atgataggaa tataacaaaa tataccaggg acatgtataa aaaatacact ggtaaaaccg
    17401 gctgcctgga tagcacatat gccgctgata tagaagagag gcgggaacag tgattacaga
    17461 aatgaaagca gggcacctga aagatatcga taaacccagc gaaccatttg aggtgatagg
    17521 taagattata ccgaggtatg aaaacgagaa ttggaccttt acagaattac tctatgaagc
    17581 gccatattta aaaagctacc aagacgaaga ggatgaagag gatgaggagg cagattgcct
    17641 tgaatatatt gacaatactg ataagataat atatctttac taccaagacg ataaatgcgt
    17701 cggaaaagtt aaactgcgaa aaaattggaa ccggtacgct tatatagaag atatcgccgt
    17761 atgtaaggat ttcagggggc aaggcatagg cagcgcgctt atcaatatat ctatagaatg
    17821 ggcaaagcat aaaaacttgc atggactaat gcttgaaacc caggacaata accttatagc
    17881 ttgtaaattc tatcataatt gtggtttcaa aatcggctcc gtcgatacta tgttatacgc
    17941 caactttgaa aaagctgttt tctggtattt aaggttttag aatgcaagga acagtgaatt
    18001 ggagttcgtc ttgttataat tagcttcttg gggtatcttt aaatactgta gaaaagagga
    18061 aggaaataat aaatggctaa aatgagaata tcaccggaat tgaaaaaact gatcgaaaaa
    18121 taccgctgcg taaaagatac ggaaggaatg tctcctgcta aggtatataa gctggtggga
    18181 gaaaatgaaa acctatattt aaaaatgacg gacagccggt ataaagggac cacctatgat
    18241 gtggaacggg aaaaggacat gatgctatgg ctggaaggaa agctgcctgt tccaaaggtc
    18301 ctgcactttg aacggcatga tggctggagc aatctgctca tgagtgaggc cgatggcgtc
    18361 ctttgctcgg aagagtatga agatgaacaa agccctgaaa agattatcga gctgtatgcg
    18421 gagtgcatca ggctctttca ctccatcgac atatcggatt gtccctatac gaatagctta
    18481 gacagccgct tagccgaatt ggattactta ctgaataacg atctggccga tgtggattgc
    18541 gaaaactggg aagaagacac tccatttaaa gatccgcgcg agctgtatga ttttttaaag
    18601 acggaaaagc ccgaagagga acttgtcttt tcccacggcg acctgggaga cagcaacatc
    18661 tttgtgaaag atggcaaagt aagtggcttt attgatcttg ggagaagcgg cagggcggac
    18721 aagtggtatg acattgcctt ctgcgtccgg tcgatcaggg aggatatcgg ggaagaacag
    18781 tatgtcgagc tattttttga cttactgggg atcaagcctg attgggagaa aataaaatat
    18841 tatattttac tggatgaatt gttttagtac ctagatttag atgtctaaaa agctttaact
    18901 acaagctttt tagacatcta atcttttctg aagtacatcc gcaactgtcc atactctgat
    18961 gttttatatc ttttctaaaa gttcgctaga tagagttcta tattagagat gtaaagagtt
    19021 ttggtgaaga ggtttgtgag tatggctttt ataaccaggg tgcaatgaga agcactaaca
    19081 gcagctagct taagaacgca taggatatac tttttatgga agtcacagag gaggaataaa
    19141 atttgaacag gattaacaga gtaacctcta ttcttattca gctgcaatca aaaaaataat
    19201 tcctgccaaa gaaattgcac agcgatttaa tataagctta aggacagttt acagagatat
    19261 ccggacactt gaagaagccg gaataccaat tggatctgag gccggaaaag gatattttct
    19321 tgtagagggc ttcctacttc tgccggtaat gtttacagcg gcggaagtgg gtgcattgat
    19381 tacagcaggg aaatttttaa attgccatgg agatgaatca tttataaagg attttgattc
    19441 agctatgtat aaaatcaaat ctattttgaa gcatggtgaa aaaaactatg cacaggagtt
    19501 ggagaacagt attaacgtgt acagcacatc tggacagaaa aatacattgg cggataacgt
    19561 tattgcagca attcagactg caatctgcaa taaaagggta atatcaattc aatatcctgc
    19621 atcaggaggg caagaaccgg aaagcagaat gatagagcct atatcactgg ggttttatga
    19681 acagaactgg tacttaatcg gttttgcagg ctaagaaatg aatataggaa ttttcgtgtg
    19741 gatcggatta aaagcatttg catagaagaa gagctctgtc aaagccatga tggctctttg
    19801 gaacaaatat taaaacaaat gctggttctg ttgcaaagta aaaaaatata gctaaccact
    19861 aatttatcat gtcagtgttc gcttaacttg ctagcatgat gctaatttcg tggcatggcg
    19921 aaaatccgta gatctgaaga gacctgcggt tctttttata tagagcgtaa atacactcaa
    19981 taccttttaa agtattcttt gctgtattga tactttgata ccttgtcttt cttactttaa
    20041 tatgacggtg atcttgctca atgaggttat tcagatattt cgatgtacaa tggcagtcag
    20101 gtttaagttt aaaagcttta attactttaa ccattgctac cttcgttgaa ggtgcctgat
    20161 ctgtaattac cttttgaggt ttaccaaatt gtttaatgag acgtttgata aacgcatatg
    20221 ctgaatgatt atctcgttgc ttacgcaacc aaatatctaa tgtatgtccc tctgcatcaa
    20281 tggcacgata taaatagctc cattttcctt ttattttgat gtacgtctca tcaatacgcc
    20341 atttgtaata agctttttta tgctttttct tccaaatttg atataaaatt ggggcatatt
    20401 cttgaaccca acggtagacc gttgaatgat gaacgtttac accacgttcc cttaatattt
    20461 cagatatatc acgataactc aatgcatatc ttagatagta gccaacagct acagtgataa
    20521 catccttgtt aaattgttta tatctgaaat agttcataca gaagactcct ttttgttaaa
    20581 attatactat aaattcaact ttgcaacaga acctcattta ctatatgggc atctctttca
    20641 ttattaatac aaagctttgt atctccgata ttaggcaaag gtgtaaacga attaggtgat
    20701 actataggat tcaacattat attaatcgtt tctttaataa tgattatctt cttatttttt
    20761 ataaatcgta gtaaaaatat ctcctatgat tatataaaag ttcaaagagg tgaagccaat
    20821 gaataaatta gaaaaatggt ctttggtatt tattattttt acatttctct cttcattagc
    20881 acttttatat ttcaaatata attttagttc ggttatgcca gtcctaagtc tttctatttt
    20941 aactatacta atattgttga cgagtattat tactgtagtt tcagttaatg atgaagatac
    21001 ttaaaacgtt cattagtgaa acaggtatta tattaaaaaa gcgtacgaat ttgtacgctt
    21061 ttttcttgtg ttattattaa aatctcataa caggaaaata ttatgagatt ttagacgctg
    21121 tcagaacgtc tcttttacat cgagtgacat tgaatcaaag tctttgtatg ttaatgatat
    21181 ataaaattat ttagtagatt cattatagta agctagatta gttgctctac ttgtttttat
    21241 tctcttttgc ctctaattta ttgagataac gataaatagt tgtacgtgaa acttgccact
    21301 gctctgcaat tgttttaatt ggcgtaccat tatcataaag tgtcttaagt aagtttaaat
    21361 cttgtttatt taatttttca ggtctacctc catatcggcc tctagcacgt gctgcaattc
    21421 gaccggctga tgatcgctct aaaattaaat tacgttcaaa ctctgcaaat gctgcgaata
    21481 aatgaaataa taattgtcct gtagaacttg atttatccat cgttatattt tcttctaaac
    21541 tatgaaaact cacacctcgt tcgttaagtt cattaactaa cgtgattaaa tcctccatgt
    21601 tccgtcctag tctatctaat ctccaaacaa caatcgtatc tcctgacctc gcaaattcaa
    21661 ttgctttatc taaaccaggt cgcttacttt ttgaaccact catatggtca ttaaatatct
    21721 tttcacaacc atatgtattt aatcgatcct cctgtaaatt caaattttgt aatccagttg
    21781 aaactcttgc ataacctatt ttcaaaatac agacctccta tatacacctt tagtgtacca
    21841 taacttgatt acgaggtctt ttgtgaacat agattttttg ttgggttttt gaacacataa
    21901 ttctatgtaa tacttactta tttagacaaa aaacaagagt gtacagaaaa tggttatttt
    21961 ctggacactc tcatctttaa taatatattt taaatgtcat taacaaaact aatttaataa
    22021 gagtcaagta tggtttacat atgtattatg tttgaaacat acctctaatt actttttact
    22081 aatatcattt aaaatgtctc gcaattcttc aatttctttg ttatttaatt cttcattttt
    22141 cgcaaaattc agcactaaac ttttcatatc ccctccatac agtttattaa gaaaggtttt
    22201 agcagttttc attttaatat cgtcttcttt aatatttgat gagtaaaaat aaatattttc
    22261 tgatttgtat cgttttataa tctctttttt atatagtctt gtgattaatg ttctaatcgt
    22321 tttatcacta acttctttat atttttgaat ttcaactaca atttcattag ctgatactga
    22381 ttttttatcc catattatat tcataacatc ccattcagcc atagatattt caacttgctt
    22441 attggtcatt taaaacaccc attcctttta atattttttc acttattaat tcagcatttt
    22501 tcccagacgg gtttccatct gataaatgtg tagcaaaata atacttatca tgatttgtaa
    22561 ttacgtaacc tacaaaccac ccattattat acttcccgtt tactatacct gtacctgttt
    22621 tcccatacag ttcatacttt tcatttttct taatcaataa tgaagaagat aattgattct
    22681 ttgctttttt actaaaatgg ttattttgtt ccatcatatt tttaaaaact attacttgtt
    22741 caagattaga tattttcaaa ctatcttcca tccaatagct tttataactt cccaaatttt
    22801 cattaccata atttaattgc ttgagttgag ccgcagtata gttctttggt atttgattac
    22861 taatacgttc gaagtaccaa ttaactgaat tttgcattgc tgtatttaaa tcttgttcct
    22921 tattccaaga ctcgaaaaga taatgtttat gattccatga catacgtgaa tttttatcac
    22981 ttataatatg acggtcaagt ccaaacagtg ctaaataaat tttgtaagtt gaatcaggag
    23041 aatatctttt tctactttct ttttcattat aaatatagta tttgtctttc ttcatgctgt
    23101 acataacgaa agatccacta tttgaaccaa aatttttact ttcatctaaa atttggtaat
    23161 cgctttgtaa gggcttttta taattataat cagttaagga ttgccccatt aaaaactggc
    23221 tttgaattat catgataaaa aaagtaaaaa tacaaataaa aattagaatt aattttgact
    23281 gctttttcag atcggcttct tttatattaa ttaatctact tttgagtaat gattttttac
    23341 cattaaatga atggcttaat atatttttgt tggaaaatgg ggtttttaat acggagtcca
    23401 taatagattc cgcataagtt ttaaattcat ttttgttaat attattaagg acaaatctat
    23461 cggcttctac ttcattgtca tgaattatct ttctttttac aatatgtact aatggattgt
    23521 aactcataat aatagagaag atattaaaga taattaaatg taaagtatct ctatttttag
    23581 catgagcata ttcatgcagt attatatatt ttagtctttt atcaattaca cttttaaaat
    23641 atgaactagg aatcaaaata atatatttcc cataccaaaa agttattgga gattgaatag
    23701 cctctgcttt tcgaatcaca atattttttt tatattgatg gttgaaaagt atcgtatcta
    23761 ttttattttt ttcattttcg tttagataaa gtgactgttt ctttaaatat ttaagatata
    23821 ataaggcttt caaaaattta aaacttaaaa taataactaa aactatccaa ataactgtgc
    23881 agatattatc aattgaatcc caattaaact tatggatatc tgttgtgaac tcttgaatag
    23941 gtttggtggt atttatgtta tggttcaaat cgtgtgactt actttcaact gtgggcgctt
    24001 gattattcac attattaaat tttataaaag agaatttaat tgggataaaa ggaattaatc
    24061 cagcaagcat agttagatac caaactttat aatttaaact ataattaaaa tagcgtttta
    24121 atatgtacct aaaaaatact aacaatagaa atataaaaca aaagcttact acgctcatta
    24181 ttagtaattt agccattttg acaccttctt tcaaatattt ataataaaca attgacatca
    24241 atattacaat tgtaatatta ttgatttata aaaattacaa ctgtaatatc ggagggttta
    24301 ttttgaaaaa gttaatattt ttaattgtaa ttgctttagt tttaagtgca tgtaattcaa
    24361 acagttcaca tgccaaagag ttaaatgatt tagaaaaaaa atataatgct catattggtg
    24421 tttatgcttt aaatactaaa agtggtaagg aagtaaaatt taattcagat aagagatttg
    24481 cctatgcttc gacttcaaaa gcgataaata gtgctatttt gttagaacaa gtaccttata
    24541 ataagttaaa taaaaaagta catattaaca aagatgatat agttgcttat tctcctattt
    24601 tagaaaaata tgtaggaaaa gatatcactt taaaagaact tattgaggct tcaatgacat
    24661 atagtgataa tacagcaaac aataaaatta taaaagaaat cggtggaatc aaaaaagtta
    24721 aacaacgtct aaaagaacta ggagataaag taacaaatcc agttagatat gagatagaat
    24781 taaattacta ttcaccaaag agcaaaaaag atacttcaac gcctgctgct ttcggcaaga
    24841 ctttaaataa acttatcgca aatggaaaat taagcaaaaa aaataaaaat ttcttacttg
    24901 atttaatgtt taataataaa aacggagaca ctttaattaa agatggtgtt ccaaaagact
    24961 ataaggttgc tgataaaagt ggtcaagcaa taacatatgc ttctagaaat gatgttgctt
    25021 ttgtttatcc taagggccaa tctgaaccta ttgttttagt catttttacg aataaagaca
    25081 ataaaagtga taagccaaat gataagttga taagtgaaac cgccaagagt gtaatgaagg
    25141 aattttaata ttctaaatgc ataataaata ctgataacat cttatagttt gtattatatt
    25201 ttgtattatc gttgacatgt ataattttga tatcaaaaac tgattttccc tttattattt
    25261 tcgagattta ttttcttaat tctctttaac aaactagaaa tattgtatat acaaaaaatc
    25321 ataaataata gatgaatagt ttaattatag gtgttcatca atcgaaaaag caacgtatct
    25381 tatttaaagt gcgttgcttt tttctcattt ataaggttaa ataattctca tatatcaagc
    25441 aaagtgacaa tagcatttta caagtatttt ttattgttcg attagggtaa acctaaataa
    25501 tacataaatt atattacaat atgtttatta tagaggctaa agtatcttag aaatttggat
    25561 agtaggtttt tcgggaataa aagtatagtt ggctttaata tataattaag ctaagctatc
    25621 atttatattt actcgattat aattcgcact tcaacttttt tataacgtaa aaattaaaac
    25681 gtagttttat ttatctttag taatatcttt ttaaacacta cagtttcttc attagttaaa
    25741 ttagcgaagt aatgattatt aagttgatag gctttctttt ctaatgttgg ccataagtct
    25801 tttgctttat ttgtactgtt tattagcaca gttcttctat tttcattatc agtttgacgt
    25861 gttattagat cctttttgga catcttatct aatattccag atattgttga aggttctaaa
    25921 tttaaagtat taccaatcgc tttaggtgta ttcaaattac tattaatcaa gcaattcaaa
    25981 acaccatatt ctgctggagt aatattatag ggacttaata aacttttaaa atgtttaaaa
    26041 actctattct gagaagtact caacaaataa tttatacaat tatctaattc cacaactaaa
    26101 acctctctta aatcattagt attgactcgc ttatcatatc atgataagtt ttgtaggaaa
    26161 atagttttgc aacaaaaaca tacttctaca aaacaattgt gaaagaaggc taataaatgt
    26221 tcaatgcggt agtagtgaga aaaagtgcat caaatgttag ttataaagta gaaaaagttg
    26281 atgaatctca tttatcgaag ggtgatgtat tagtaaaagt ggtatactct tcaataaatt
    26341 ataaggatat gctagcttta caatataaag gcggtgtaat tagagattat cctatgattc
    26401 ctggtataga ttttgcaggt attgttgaat caagttcgaa tgataagttt aaagaaggcg
    26461 ataatgtatt agttactggt tatgatgttg gcgtgacaca tacaggtgga ttttcagaat
    26521 atgcacaagt gcctggagag tggattgttc ctattcccca agaaatgtct attaaagagt
    26581 ctatggtata tggcacagcc ggttttacgg cagcattatc aatttttgaa ctagaaaaat
    26641 atggaatgaa tatcaaatca caacctgaaa ttttagtgtc tggggctaca ggtggtgtgg
    26701 gcagtgttgc tatacaaatt ttacataaaa ttggatatga aaatatcact gctatcgtaa
    26761 gaaaagaaaa gcaaatagaa atcgcaaaaa aattaggtgc aaaacaagta ataataattg
    26821 aagatgataa taaaccgctt aaaaaaggta tttttgatta tttcttagat acagtgggga
    26881 gtaatgtaac attatacggt ttaaaacgtc taaattatca aggtgttgct actgtatgtg
    26941 gaaatgtagc aggaaattca cttaacgcta atatattacc gtttattctt agaggtatta
    27001 aattaattgg cattgattct gtatatgttg atcataatat ccgtgaagat atatggagta
    27061 agttagca
//
