LOCUS       NZ_CP103163             9010 bp    DNA     circular CON 14-SEP-2023
DEFINITION  Parabacteroides distasonis strain BFG-426 plasmid unnamed1, complete
            sequence.
ACCESSION   NZ_CP103163
VERSION     NZ_CP103163.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN30323342
            Assembly: GCF_024759585.1
KEYWORDS    RefSeq.
SOURCE      Parabacteroides distasonis
  ORGANISM  Parabacteroides distasonis
            Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae;
            Parabacteroides.
REFERENCE   1  (bases 1 to 9010)
  AUTHORS   Tisza,M.J., Smith,D. and Dekker,J.P.
  TITLE     Genome Sequencing of Bacteroides fragilis Group Isolates with
            Nanopore Technology
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9010)
  AUTHORS   Tisza,M.J., Smith,D. and Dekker,J.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-AUG-2022) LCIM, National Institute of Allergy and
            Infectious Diseases, 9000 Rockville Pike, Bethesda, MD 20892, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 430x
            Sequencing Technology             :: Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/14/2023 06:28:23
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,585
            CDSs (total)                      :: 4,482
            Genes (coding)                    :: 4,227
            CDSs (with protein)               :: 4,227
            Genes (RNA)                       :: 103
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 80
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 256
            CDSs (without protein)            :: 255
            Pseudo Genes (ambiguous residues) :: 0 of 256
            Pseudo Genes (frameshifted)       :: 202 of 256
            Pseudo Genes (incomplete)         :: 58 of 256
            Pseudo Genes (internal stop)      :: 18 of 256
            Pseudo Genes (multiple problems)  :: 20 of 256
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP103163.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9010
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /strain="BFG-426"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /plasmid="unnamed1"
                     /geo_loc_name="USA: Bethesda"
                     /collection_date="2003-05-05"
     gene            1..1656
                     /locus_tag="NXW68_RS22850"
                     /old_locus_tag="NXW68_22850"
     CDS             1..1656
                     /locus_tag="NXW68_RS22850"
                     /old_locus_tag="NXW68_22850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008669305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_008669305.1"
                     /translation="MQKTYLYLMVCVIGAMSLASCSEDSISPDAGGDGDGDSTTEVPLA
                     QVAKPKPNPWLAQEEYSITHFNSAQTDAFSSAVKDGTFNIDLSKCQMTWSGPVNLMTLA
                     STSPNYMWGMSSDRVSYLDISDGKLERVAEAGLPGITMKTQEQLTRIIADHATYDELSK
                     TVTDILGPVPQMSMANGNYVLCDKDNYAYTNAGQVMARYRLANPNNPKDGIMLDHQIRL
                     TNFTFGSFTLVGATMTYDGHLVVAAQNGLLVLNRALTTIEDSYPLPSDQILTNSICIDE
                     NGGVYVASNSRTPGGKGLMQKLICKDGKISTSQADGAWQAYYDGGPQAPCIKLGHGTGS
                     TPTLMGFGQDKDKLVVITDGSKRMKLVAFWRDEIPSDAQQVAGYDKRIAGVHEVTCGLG
                     TSTEWIQSEQSVVVGGYDAFVVNNINVTNQEINDKIIGVIAIGPIVKGPQGAECVRWNT
                     KEKKWESKWTRSDVSSVSMIPAVSIKSEMVFVCGWNDASGWEVTGLDWKSGATRHRSIL
                     GKNNRANGAYAIIQYLANGDLLFNSVAGPIRVKY"
                     /name="hypothetical protein"
     gene            complement(2211..3089)
                     /gene="btgB"
                     /locus_tag="NXW68_RS22855"
                     /old_locus_tag="NXW68_22855"
     CDS             complement(2211..3089)
                     /gene="btgB"
                     /locus_tag="NXW68_RS22855"
                     /old_locus_tag="NXW68_22855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007851393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mobilization protein BtgB"
                     /protein_id="WP_008669303.1"
                     /translation="MNVKIQGSGNGTYANTGSCVAVTNYLQHEDLERMKKGEEVQPFFN
                     QFRDYVSAREVTFKIDNNKAKLSRTDAKFYVITVSPSEKELRCMGRTPQECAEALRRYI
                     RQDVMRNYAEGFGKGLKSDDVEYYAKIHFNRDGESDSDMHAHIIVSRKDRSNTRKLSPK
                     TNHTGKKNCGNVKGGFDRTDFFRKCESSFDRRMGFDREPEESFDYLNAVKNGSPAEIAR
                     QVERAERIRKEKWDKLKAELQSRQEPEKSKNQQVEKTPDIEQPIPKKKQQEEDLELLKK
                     PKRSRGFGMGM"
                     /name="btgB"
     gene            complement(3086..3691)
                     /gene="btgA"
                     /locus_tag="NXW68_RS22860"
                     /old_locus_tag="NXW68_22860"
     CDS             complement(3086..3691)
                     /gene="btgA"
                     /locus_tag="NXW68_RS22860"
                     /old_locus_tag="NXW68_22860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007851392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mobilization protein BtgA"
                     /protein_id="WP_008669301.1"
                     /translation="MDKETTTSVTIDRKTFARLDRLAKSNNVSKKEFLSCALEYFEKYG
                     INPVEHESPAKEMQKLIKRCDQVIAFIRKQEQDFLRPACEAMGSTSMRVTMSMDSILTE
                     KKFSQYQKDNDLFMRDLASLAGIREQALDRAEKAVGQSRDMLLKNQQAIYARLDAVTQR
                     QEKIFSYIASYIDAKGKAGLFDDIKALYKNEKNKREKI"
                     /name="btgA"
     gene            4083..4430
                     /locus_tag="NXW68_RS22865"
                     /old_locus_tag="NXW68_22865"
     CDS             4083..4430
                     /locus_tag="NXW68_RS22865"
                     /old_locus_tag="NXW68_22865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007851390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_008669299.1"
                     /translation="MEAKSRFKVKLSNEAQEFLDGLPNKVREKIISNIRKSTFVLDPDL
                     FKKLDDTDIWEFRTFYNKTKYRLLAFWDKDDKINTLVIATHGFIKKTQKTPPKEIAKAE
                     EIRKDYFNSKR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            4436..4750
                     /locus_tag="NXW68_RS22870"
                     /old_locus_tag="NXW68_22870"
     CDS             4436..4750
                     /locus_tag="NXW68_RS22870"
                     /old_locus_tag="NXW68_22870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007851388.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_007851388.1"
                     /translation="MEAKKFYTLEEIEDKYIGEKGTPKRDAYEEELNSFLIGEAIKQAR
                     QSKNLTQEELGNLIGVQRAQISRIENGKNLTFSTIARVFKAMGISAKLEIGSMGKVALW
                     "
                     /name="helix-turn-helix transcriptional regulator"
     gene            5226..6203
                     /locus_tag="NXW68_RS22875"
                     /old_locus_tag="NXW68_22875"
     CDS             5226..6203
                     /locus_tag="NXW68_RS22875"
                     /old_locus_tag="NXW68_22875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008669318.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_008669318.1"
                     /translation="MEKKDKKQRDIVLSQDNALTTARYKFDLIEKRALYSIIRNIRAQY
                     IENENGRRDLFDDLIITIHEEELKKCGDNTKMQNIYDALKRLRNRDIEINNEKMWLSIG
                     FVNYVKHIKNKSYFEVQVSKEVLPYYVELAQNFTSYSMTVAIALKSTFSQRFYELCCQY
                     RNAGFFFYTVEKLREMFMLEKKYKRGCDFKRRVLDDPQKELRELYNAGQCDLYFEFEPK
                     SYKGKEVTEYKFYVYTRQTEQQKLLEYESAKQAIIYITTTISRFSKSDKGYVKRVVNAV
                     QLHPEIAVQVAQKIQKKFEQYIDKPAKQIGAIIRVCLMEDFGIE"
                     /name="replication initiation protein"
     gene            6282..6452
                     /locus_tag="NXW68_RS22880"
                     /old_locus_tag="NXW68_22880"
     CDS             6282..6452
                     /locus_tag="NXW68_RS22880"
                     /old_locus_tag="NXW68_22880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_009276913.1"
                     /translation="MKTGDKVIVPAEINGYGRDLRAIVTEIEKFAGAIFVTVIFTEPCP
                     EACGRGGGCLP"
                     /name="hypothetical protein"
     gene            6577..7100
                     /locus_tag="NXW68_RS22885"
                     /old_locus_tag="NXW68_22885"
                     /pseudo=""
     CDS             6577..7100
                     /locus_tag="NXW68_RS22885"
                     /old_locus_tag="NXW68_22885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016271957.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            7130..>7482
                     /locus_tag="NXW68_RS22890"
                     /old_locus_tag="NXW68_22890"
                     /pseudo=""
     CDS             7130..>7482
                     /locus_tag="NXW68_RS22890"
                     /old_locus_tag="NXW68_22890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005852953.1"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /name="DJ-1/PfpI family protein"
     gene            7694..8791
                     /locus_tag="NXW68_RS22895"
                     /old_locus_tag="NXW68_22895"
     CDS             7694..8791
                     /locus_tag="NXW68_RS22895"
                     /old_locus_tag="NXW68_22895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008781140.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_009276911.1"
                     /translation="MDTCLDLIALQYTCMIVMAMLAFFVFVSRYYVTCRNRQFEQSRWM
                     IVVALLLFVVHYMCQMRLGWRQQGNDVGVLFNLLFYSPSAILLSWSQLNILRAGHRRWS
                     FMRYGVVGYALMVLCIVAGVISNGSLHIGPMLYVADAIHFFTLLYYTWAPLRELGNVQR
                     RLDSEHGNPADAYLRTMRFGFFVVCAFAVISPLYILSRPLLFVFGPLGLISLSLFIVSF
                     TALGFSMSEGVTEIVTETNDEIAAAKVFREIGPERIAEIDMAVSKWRSEGGFRDSDLTL
                     SSFARRIMVNRTDVASYLTSIYGKNFRTWLSGIRVEEAKALMAAHPEYSNEVVSMECGF
                     SSRVYFQRLFKERTGLTPAEWRRQR"
                     /name="helix-turn-helix domain-containing protein"
     Typing          5227..6203
                     /name="rep_cluster_1097"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(2215..3089)
                     /name="MOBB"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgcaaaaaa cctatcttta tttaatggtg tgtgtcatag gggctatgtc tttagcttcg
       61 tgttccgaag attctatttc tcctgatgct ggtggcgatg gcgatggcga cagcactacc
      121 gaagtgcctt tggcacaagt tgcaaaaccc aaacctaacc cttggcttgc acaggaagag
      181 tatagtatta cgcacttcaa ttcggctcag actgatgctt tctcgtctgc tgtcaaggat
      241 ggaactttca atatcgatct ttccaagtgt cagatgacat ggagcggtcc tgttaatttg
      301 atgactcttg cttcgacttc gcccaattat atgtggggta tgagtagcga ccgcgtgtcg
      361 tatcttgaca taagcgacgg caaacttgaa agggttgccg aggctggctt gccagggatt
      421 acaatgaaga cccaggagca actgacacgt ataattgccg atcatgctac ttacgacgaa
      481 ctttccaaga cggttaccga tatattgggt ccggtgccac aaatgtctat ggccaacggt
      541 aattatgtct tgtgcgacaa ggataactat gcttacacca atgcaggtca ggtaatggca
      601 cgctatcgcc ttgccaatcc taataatccc aaggatggta tcatgttgga tcatcagata
      661 agacttacga attttacctt cggctctttt acactcgtag gcgctactat gacctatgac
      721 ggacaccttg ttgtggctgc tcagaacgga cttcttgtgc tgaatcgtgc tcttactaca
      781 atcgaagatt cataccctct tccatcagac cagattctca ccaactctat ctgcatcgac
      841 gagaatggcg gtgtttacgt agcaagtaac agccgcacac caggcggaaa aggccttatg
      901 cagaaactca tctgcaagga cggcaaaatc tccacctccc aggctgatgg tgcatggcaa
      961 gcctattacg acggtggtcc gcaagcacca tgtatcaaac tcggacatgg cactggttca
     1021 acgcctacac ttatgggctt tggccaagac aaggacaagc tggtagttat taccgatggc
     1081 tctaagcgta tgaaactggt agctttctgg cgtgacgaaa tcccctcaga cgcacagcaa
     1141 gtggcaggat acgacaagcg tatagccgga gtgcacgagg ttacatgtgg tcttggaaca
     1201 tcaacagagt ggatacagtc tgagcagtct gttgtagtag gcggctatga cgcctttgtt
     1261 gtaaacaata ttaatgttac caatcaggaa ataaacgaca agattattgg tgtaatcgct
     1321 attggtccta ttgtcaaagg ccctcaaggt gccgagtgtg tacgttggaa tacaaaggag
     1381 aaaaagtggg agagtaagtg gacgcgcagc gatgtaagtt ctgtaagtat gattcctgcc
     1441 gtaagtatca agtcagagat ggtatttgta tgtggctgga acgatgcttc gggctgggaa
     1501 gttacaggac ttgactggaa gagtggtgcc acacgtcacc gcagcatatt gggcaagaac
     1561 aaccgagcca atggtgccta cgccatcatt cagtatcttg ctaacggcga ccttttattc
     1621 aactctgttg ccggaccaat ccgcgtaaaa tattgagata atttaatcat catataacag
     1681 ttatgtcaat acttcactaa aaaattaccg aagtattgta atgacacacc cgaacatatt
     1741 gaaatgttct atcagttcca taaacaaggc ttctgttctt tattcctaga tacaggtgat
     1801 aaataacaga taagaaacag attataacaa gcctccggcg gggttttcgc tgggggattt
     1861 tgacctttgc acatataaaa agcaaaaaga aagcgatatc ggagcgtata ccataaaaca
     1921 gaccaccgac tattacaaaa cgatattacg tgcctaactg atcggggcag ttcctccacc
     1981 atgcggacaa atcccggtaa caaaatgaca aaacggacac tcaccaaaga acaacatttt
     2041 tttctttttt cctaaacacc ttccagcgaa gcacagtgta tttgtcaagg gcgaagggta
     2101 aaaaatctcc tgtgctcgct tcgctcgtgc ggtatttttt acccggagag tgaaacgtcc
     2161 ctttacaaat gcggcgtgcg gagttacctt tgtgccggaa aatagaaaaa tcacatgccc
     2221 attccgaaac ctctgctcct ttttggcttc ttcaggagtt ccagatcttc ctcctgctgc
     2281 ttctttttgg gaataggctg ctcgatgtcc ggcgttttct ccacctgttg atttttcgac
     2341 ttctccggct cctgccggga ttgaagctct gctttgagtt tgtcccattt ctcctttctg
     2401 atgcgttccg cacgttccac ctgccgggct atttccgccg gacttccgtt cttgacggca
     2461 ttaagatagt cgaagctttc ctccggctcc cggtcaaacc ccatgcgccg atcaaaagag
     2521 ctttcacact tccggaaaaa atccgtccgg tcaaaacctc ccttcacgtt gccgcagttc
     2581 ttcttcccgg tgtggttcgt tttagggctt aacttcctgg tgttgctccg gtctttccgg
     2641 ctgacgatga tatgtgcgtg catatcgctg tcactttcac cgtcccggtt gaaatggatc
     2701 tttgcataat attccacatc atcgcttttc aagccttttc cgaagccctc cgcatagttt
     2761 ctcatcacat cctgccgtat gtaccgccgt aaggcttccg cacactcctg cggagttctg
     2821 cccatgcagc gcagctcctt ctctgaaggg ctgacagtga taacatagaa ctttgcgtca
     2881 gtccggctta acttagcctt gttgttgtct atcttgaatg tgacctccct tgcgctcacg
     2941 tagtcccgga actggttgaa gaacggctgc acctcctccc ctttcttcat cctctccaaa
     3001 tcctcatgct ggagatagtt cgtcaccgca acacaactgc ctgtattggc atatgtgccg
     3061 ttaccgcttc cctgtatctt cacgttcata tcttttccct tttgttcttc tcgttcttgt
     3121 acaaggcttt tatatcatcg aaaagcccgg cttttccttt cgcatcgata tagcttgcga
     3181 tataggagaa gatcttctcc tgcctttgcg tcacagcgtc cagccttgca taaatggctt
     3241 gttggttctt cagaagcata tccctcgact gaccgactgc cttttccgcc cggtccaaag
     3301 cctgctccct tatcccggca aggcttgcaa ggtcacgcat gaataggtca ttgtcttttt
     3361 ggtattggct gaactttttt tccgtaagta tcgagtccat gctcatggtc accctcatac
     3421 ttgtactgcc catggcttca caagccggac gcaagaaatc ctgctcctgc ttccggatga
     3481 acgctatcac ctgatcacag cgtttgataa gtttctgcat ttcctttgcc ggactctcat
     3541 gctcaaccgg gttgatgccg tacttctcga agtactccag cgcacaggaa aggaactctt
     3601 tctttgatac attattggac tttgccagcc tatcaagccg ggcaaacgtt tttcggtcaa
     3661 tggtgacaga agtggtggtt tccttatcca tacaattgcg gttttaattg ctgtttatat
     3721 tattaaatct ctgatttcca aaggtatgat tttaaccaca atttcaaact aattgcggtt
     3781 aaaaaactta aacggctgat attcagccgt aaccccgtag ggcaagagga aaaacagggt
     3841 aaagcccggt ttcctcttgc tattctttcg actgccgagc aatcgacgaa caccctcccc
     3901 tgcggtacgg cgaaagctcg tacaaggggg acggggagaa gtcggagcga ggcacaaaga
     3961 aagaacctat tccacaaaca aaaaaacaca tcaaaacggc acaacaggct gcataaaata
     4021 tcaatatttt gtttcgctat atggaaacaa aatattatct ttgcaacact aaaaaacttt
     4081 atatggaagc aaaatcaaga ttcaaggtca aattatccaa cgaagcccaa gagtttttag
     4141 acggattgcc caacaaggta cgtgagaaga tcattagcaa tattcgtaaa tccacctttg
     4201 tacttgatcc agatttattc aagaaattgg atgatacgga tatttgggaa ttcagaacgt
     4261 tctataacaa aaccaagtac aggcttcttg ctttttggga taaggacgat aagataaaca
     4321 ctctggtaat cgcaacacat gggtttatca agaaaaccca aaagacacct cccaaagaaa
     4381 tagccaaagc cgaagagatt agaaaagatt attttaattc aaaaagataa agcgtatgga
     4441 agcaaagaaa ttttatacac tcgaagaaat cgaggataaa tacatcggag aaaaaggtac
     4501 tcccaaacgt gatgcctacg aagaagaact taactctttt ttgataggtg aagccattaa
     4561 acaagctcgc caatcaaaga acttaaccca agaggaatta ggtaatctga taggagtgca
     4621 acgggctcaa atctcccgaa ttgaaaacgg taagaattta accttttcca ccattgcaag
     4681 agtttttaag gctatgggga taagtgctaa acttgaaatc ggaagcatgg gtaaagttgc
     4741 gttatggtaa ctaactatac aacaaaaagt tacattaaat ccgggatgcg ttttcgctcc
     4801 cggaaacttc ttgttttata cattaaaagt catatttata caaaatttaa cacgccaaaa
     4861 aatcttccta atccgttgca cttggcttta cttgtttcca ctctctccca ttctccggaa
     4921 attcgtcgta tcaaaaaaca cgctgaaaag tggagcgaag cgacctctat aaaccaaaaa
     4981 agaaacactc cattgcttta cggtaatttt tagtttcttt ttagttactt ttacggcata
     5041 gcataacaca ttgtgctgta atatcttaca aaggtcatct acgacaaatt tccgagcatc
     5101 tacgacaaat ttccgagcat ctacgacaaa tttccgaaaa aaacggttat ctacgacaaa
     5161 tattctacgc catatatttg tttttgtcgt agataaatat ttcctttgcg aaaagcatta
     5221 aagtcatgga gaagaaagac aagaaacaga gggatatagt cctgtcgcaa gacaatgcgc
     5281 tgactaccgc acgctacaag ttcgacctta tcgaaaaacg tgccctatac tccattatac
     5341 gaaatatccg ggcgcaatac atcgagaacg agaacggcag acgggactta ttcgatgatc
     5401 tgattatcac catacacgag gaagaactaa agaaatgcgg tgacaatacc aagatgcaaa
     5461 acatctacga tgcgctaaaa cggcttagaa atcgcgatat agagattaac aacgaaaaaa
     5521 tgtggctaag tatcggtttt gtcaattacg tcaagcatat caaaaataaa tcgtattttg
     5581 aggtgcaagt ttccaaagag gtactaccct attacgtgga actcgcccaa aacttcacga
     5641 gttactccat gacggtagca atcgcactca aaagcacatt ctcgcaaagg ttttacgaac
     5701 tgtgctgcca ataccgaaac gccgggttct ttttctacac agtcgaaaag cttcgggaaa
     5761 tgttcatgtt ggaaaagaaa tacaaacggg gatgcgattt caaaaggcgt gtacttgacg
     5821 atccgcaaaa ggaactccgg gagttgtaca atgccggaca atgcgattta tacttcgagt
     5881 tcgagccaaa gagctacaaa ggcaaggaag ttaccgaata caaattctac gtttacacaa
     5941 ggcaaaccga acaacaaaag ctattggaat acgaaagcgc aaaacaggcg atcatctaca
     6001 taacaaccac tatttcgagg ttctctaaaa gtgacaaagg atatgttaag cgtgtagtga
     6061 acgccgtaca gttacacccg gaaatagccg tacaggtggc gcaaaagata caaaagaagt
     6121 ttgagcaata tatagacaag ccagccaaac agataggggc tatcatccgg gtttgcttaa
     6181 tggaagattt tggtatagaa taaaaaacat acaagtatga aaacaggtga taaagttatc
     6241 gtaccagccg aaataaggta tagaataaaa aacatacaag tatgaaaaca ggtgataaag
     6301 ttatcgtacc agccgaaata aacggctatg gcagagattt acgggcaata gttacagaga
     6361 tagagaagtt cgccggggca atattcgtaa cagtgatatt caccgaacca tgtccggaag
     6421 cctgcggaag aggggggggg tgtttaccat gacttccagc taatagcaag gtgatttatt
     6481 ttgctataat cgcaataaat tgcaataata tctgtgataa attgctataa taatacttat
     6541 aactaccttt gcaacagaat atagcatttt acagcaatgg agaaaggaca ggaaagcaag
     6601 caaaagagga aaacaccgct taccaccata gcgataagcc aagagtacgc caaaaaatta
     6661 gacgagtatt taaacggtac gggtataact cgcaaagaat ttgtcgagtt gtccgttgat
     6721 tatttccaaa gaaccgggtt cgacctccgg ggtgaagctt ttgacctctc cccattagaa
     6781 aaggttgccg ggcggctgga acaatccgca aagatcatgg aacgacacaa cgaggggacg
     6841 gaagcggtgc acctgcttct ccaagctgtc cgggaacaga ccgccaagca actcccagcg
     6901 ccggaactga tcgcccatgc tgccgaagaa aaagcaaagg cagaagccaa aagcgaagaa
     6961 caagaaaggg agattgcccg gctgcgctcc gaaaactccg ctttgctgga gtacaaagaa
     7021 aaggcatacc gggaactatg ccggatacgt gatgatgaca aaaaaacata gggaagataa
     7081 aagtaaatat agagttataa aagaacattt ataaataaaa aaatcatgaa taaagaaatt
     7141 ttatttattt atccttttgc cggattatgc agcacatgaa gctgtgtact tttcacaggc
     7201 tattacagct gatgattttg ccatgaaaaa aatccaaaat atgtcaataa ggttgtcgca
     7261 cccaccttag aaccaataag ttcgattggt ggattccgca cattacccga ttattcgttt
     7321 gacacaatgc ctgatgatta tgtagcattg gtattaattg gcggttttgg ttggaataca
     7381 cctgttgcag aaaaggttat gccaattatt aaaagtgcta ttgaacaaga aaaggttata
     7441 ggtgcgattt gtaatgcagc ttcattcatg gctaagtgtg gtattgaccg agaaacaaca
     7501 tcaaaaactt tgcagaagtc atccgtaata cagaaaatct cagtaacttt gtcctcggta
     7561 atcatagcaa ttattgtctg taaacttttg atatttaaca ctctaagatt acaacaattt
     7621 ttcgctaatc accatttttc aggcacttat atttcgtcga actcacgtta aattatttaa
     7681 tatacataca atcttggata cttgcttaga ccttattgct cttcaatata cttgcatgat
     7741 tgtgatggcc atgcttgcat tttttgtgtt tgtgtcgcgc tactatgtaa cttgccgtaa
     7801 cagacagttt gagcagtcgc gttggatgat tgttgtggca ttactattgt ttgttgtaca
     7861 ctacatgtgt cagatgcggt tgggttggcg acaacagggg aacgatgtgg gtgttctgtt
     7921 taatctgctg ttttattcgc cttcggctat tttgttgtca tggtcgcagc ttaatattct
     7981 gcgcgctggg catagacgtt ggagttttat gcgctatggc gttgttggat atgctcttat
     8041 ggtattgtgc atagtcgcag gtgttatttc aaatggcagt ctgcatattg gtcctatgct
     8101 atatgttgct gatgctattc atttctttac tctattgtat tatacatggg caccgctgag
     8161 ggaacttggt aatgttcaac gtcggctcga cagtgaacat ggtaatcctg cagatgccta
     8221 cctgcgcact atgcgctttg gtttttttgt ggtgtgtgct tttgctgtaa tttcgcctct
     8281 ttatatattg tcgcggccgc tgctctttgt ctttggacct ttgggattga tttcgctttc
     8341 gctgtttatt gttagtttta cggcgcttgg atttagtatg tccgagggag taactgagat
     8401 tgttaccgag actaacgacg agatagccgc tgctaaagtc tttagggaga ttgggcctga
     8461 gcgtattgcc gaaatagata tggcggtaag caaatggcga agcgagggcg gttttagaga
     8521 tagcgacttg acattatcct cgtttgctcg tcgcataatg gttaatcgta ccgacgttgc
     8581 ttcgtatctg acttccatat atggtaagaa tttccgtaca tggctttcgg gtattcgcgt
     8641 ggaggaggca aaggcactca tggctgcaca ccccgaatat agtaacgagg ttgtttctat
     8701 ggagtgcggt ttctcgtcgc gtgtgtattt tcagcgtctg ttcaaggaaa ggacgggctt
     8761 gactcccgcc gagtggcgcc gtcaacggta atatactggt tatgtgtgcg tttgctactg
     8821 aatgtaaggt gtaacttttg tacgaaggtt acataataag gcaaagtgta acctttctta
     8881 ctgtgacgta tcctttctat aagagtgaca cacaagtgat gtctttgagg tttttgatgg
     8941 ttgatgctcc tgtatctttg catgaggaaa ttcaaactat tcaaatataa attctcaaaa
     9001 acaattcact
//
