LOCUS       NZ_CP102073            21806 bp    DNA     circular CON 20-AUG-2023
DEFINITION  Enterococcus faecalis strain JF3A-4253 plasmid pJF3A-4253-4,
            complete sequence.
ACCESSION   NZ_CP102073
VERSION     NZ_CP102073.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN30011847
            Assembly: GCF_024579795.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecalis
  ORGANISM  Enterococcus faecalis
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21806)
  AUTHORS   Chae,J., Oh,J. and Jeong,J.
  TITLE     Enterococcus faecalis JF3A-4253 complete genome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 21806)
  AUTHORS   Chae,J., Oh,J. and Jeong,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2022) Division of Biotechnology, Jeonbuk National
            University, Kobongro, Iksan 54596, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.9.4b
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 103.0x
            Sequencing Technology :: Illumina iSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 08/20/2023 05:03:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,008
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,882
            CDSs (with protein)               :: 2,882
            Genes (RNA)                       :: 81
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 11 of 45
            Pseudo Genes (incomplete)         :: 31 of 45
            Pseudo Genes (internal stop)      :: 6 of 45
            Pseudo Genes (multiple problems)  :: 3 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP102073.1.
            Bacteria and source DNA available from Bacteria.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..21806
                     /organism="Enterococcus faecalis"
                     /mol_type="genomic DNA"
                     /strain="JF3A-4253"
                     /isolation_source="Rectal swab"
                     /host="Pig"
                     /db_xref="taxon:1351"
                     /plasmid="pJF3A-4253-4"
                     /geo_loc_name="South Korea"
                     /collection_date="2020"
     gene            complement(join(21223..21806,1..1189))
                     /locus_tag="NP948_RS14810"
     CDS             complement(join(21223..21806,1..1189))
                     /locus_tag="NP948_RS14810"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlwI family type II restriction endonuclease"
                     /protein_id="WP_256969064.1"
                     /translation="MSRVRRRKPITFDTTLRNPGRIPQFISVLSEFEGKVIDDKLALEL
                     EGEIIRQKIFEPTKATLGTYMKEYNKKFHFVAADQSEEAASKVEEIYIQWEKGSPGSVP
                     LEKITYLLENTITAHKDRGWKGGWESRIHTQFNFLNELGFVRVVKGEKIIISKNGKLMI
                     HEYSNGYPIKDTYDESFEQSAFLNAFSKYQVNNPYRSNTIKVNFFPLVLNVINYLDEKY
                     QRPGISKQDLPFIITWGNDDYQTLAEYIYQFRVKFGYNTSNELVYEYAMNLLDDSTPND
                     TIAPATVDFIEQKKRDYKFDKIILETPDEVIRKLRLTMLISLRGAGRFIDINKNELEKI
                     KHVLANYSSNIDFDDDVQKYLEYMGDIDNSLMFVSDAQESQEAKYAKEVAIEKWAKEYD
                     WTFLKEEMVNSVEKRPSSHLILKYVKETARLEFLSAIVIKKALPKLKVVANYKADDQGI
                     PFNTASGGKRNLIGADIDVFEDNIHAILEPTISKQRSFQVEHELPSIRNHVLGTANKDV
                     EEGNNFKEWFSLFIASNITRDVGDQVALIKQTNGVEIYPWDIKDFVEYSERVSTIRDYK
                     KIRNYVKPQSMPVF"
                     /name="AlwI family type II restriction endonuclease"
     gene            complement(1281..2255)
                     /locus_tag="NP948_RS14815"
     CDS             complement(1281..2255)
                     /locus_tag="NP948_RS14815"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543632.1"
                     /GO_function="GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity [Evidence
                     IEA]"
                     /GO_process="GO:0006306 - DNA methylation [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
                     /protein_id="WP_256969065.1"
                     /translation="MQTTLFPTETLEVVAPMKKKGKAIRSPLFYVGDKYKLMPQLKELF
                     PKNINNYYDVFSGGGSASINVIADKIIMNDVDEKVVELHRFLQEQSSDIELFIENMYEL
                     IREYGLSLSELGKNSEIEELKKEFKKTYFAKYNKQAYLKLRDDYNKNQSNTMLLYLLLI
                     YGFNHMIRFNGQGQFNLPVGNVDWNKNVSTALRNYSQWYNNNNIEISSGMDFEDFVNFY
                     DFKNGDFLYFDPPYLITFSDYNKLWGEDEERRLYKLLDELDSKGIKWGLSNMYNHKGKT
                     NEILLEWGKKYNEYDIKSNYISRFDNTIKKDSKEIYITNYTYE"
                     /name="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
     gene            complement(2255..3487)
                     /locus_tag="NP948_RS14820"
     CDS             complement(2255..3487)
                     /locus_tag="NP948_RS14820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543631.1"
                     /GO_function="GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity [Evidence
                     IEA]"
                     /GO_process="GO:0032775 - DNA methylation on adenine
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="WP_256969066.1"
                     /translation="MLLETYLKNNNTNIRQMHIVSGIPETTVRGINKRDFSKWSVTHFD
                     AIARTVGKERHVVMQELEALKEQADNFAPLGRYNLENRRYIGNKNKLLNWISDLIDAHT
                     EGNSFFDVFAGTGVVSKEMLGKYDSFIMNDFLFSNNIIYKAFFSNDSFDSNKLLSRQEE
                     FNRIITNKEDDDYFSDNFGGKFFSVHDAKVIGEIRTRIEKDKSLTEKERAILIASLIYS
                     SDKIANTVGHYDAYRKKVQIADRFKFELVNPLDTSSKDIQIFREDSNELVRKISGDVAF
                     IDPPYNSRQYSRFYHVLEGIAKWDKPELGGVAMKPPAENMSDYSRSSAPKVFDDLIQNL
                     DVKYIVVTYNNTYKSKSSSSKNKITHDEILESLNKVGKTKSFEMPFQFFNAGKTDLKDH
                     KEFVFITEVGK"
                     /name="DNA adenine methylase"
     gene            3736..4420
                     /locus_tag="NP948_RS14825"
     CDS             join(3736..3768,3770..4420)
                     /locus_tag="NP948_RS14825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_256969067.1"
                     /translation="MNHFKGKQFKKDVIIVAVSYYLRYNLSYREVQELLYDRGINVCHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGGFYQGIEHRTIKYL
                     NNLIEQDHRPVKRRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVL
                     LGIPA"
                     /name="IS6 family transposase"
     gene            complement(4484..5347)
                     /locus_tag="NP948_RS14830"
     CDS             complement(4484..5347)
                     /locus_tag="NP948_RS14830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016301 - kinase activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="WP_256969069.1"
                     /translation="MANIVNFTDKQFENRLNDNLEELIQGKKAVESPTAFLLGGQPGSG
                     KTSLRSAIFEETQGNVVIIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAIIS
                     RLSDQGYNLVIEGTGRTTDVPIQTATMLQAKGYETKMYVIAVPKINSYLGTIERYETMY
                     ADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETPSISP
                     KETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKLESLQPPTPPIPKI
                     PKLPGL"
                     /name="zeta toxin family protein"
     gene            complement(5349..5621)
                     /locus_tag="NP948_RS14835"
     CDS             complement(5349..5621)
                     /locus_tag="NP948_RS14835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="WP_000301765.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELNKNDSQLLEVN
                     LLNQLKLAKRVNLFDYSLEELQAVHEYWRSMNRYSKQVLNKEKVA"
                     /name="antitoxin"
     gene            complement(5638..5853)
                     /locus_tag="NP948_RS14840"
     CDS             complement(5638..5853)
                     /locus_tag="NP948_RS14840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="WP_001835296.1"
                     /translation="MIVGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETA
                     KNGGNVKEVMDQALEEYIRKYLPDKL"
                     /name="peptide-binding protein"
     gene            complement(5945..6841)
                     /locus_tag="NP948_RS14845"
     CDS             complement(5945..6841)
                     /locus_tag="NP948_RS14845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_002387620.1"
                     /translation="MIQYYYTKKEWGVVMEKEELKILEELRRILNSKNEAIVILNNYFK
                     GGVGKSKLSTMFAYLTDKFNLKVLMIDKDLQATLTKDLAKTFKVELPRVNFYEGLKNGN
                     LASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIIIDTV
                     PTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFVPYLV
                     DTDSATIKSNLEELYKQHKEDNLVFQNIIKRSNKVSTWSKNGITEHKGYDKKVLSMYEN
                     VFFEMLERIIQLENEKE"
                     /name="ParA family protein"
     gene            complement(6930..9074)
                     /locus_tag="NP948_RS14850"
     CDS             complement(6930..9074)
                     /locus_tag="NP948_RS14850"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_256969070.1"
                     /translation="MSTVILAEKPSQALAYASALKQSTKKDGYFEITDPLFTDETFITF
                     GFGHLVELAEPGHYDEKWQNWKLESLPIFPDRYDFEVAKDKGKQFKIVAKLLKQANTII
                     VATDSDREGENIAWSIIHKANAFSKDKTFKRLWINSLEKDVIRSGFQNLQPGMNYYPFY
                     QEAQTRQIADWLIGMNASPLYTLNLQQKGVQGTFSLGRVQTPTLYLIYQRQEAIENFKK
                     EPFFEVEASIKVNQGSFKGVLSPTQRFKTQEELLAFVSSKQAKIGNQEGRIADVQTKEK
                     KTNSPSLFSLSSLQSKVNQLYKATASQTLKAMQGLYEAKLLSYPRTDTPFITENEFAYL
                     KANFGKYSGFLGLDLEMVQTEPRKRYVDGSKVQEHHAIIPTKQVPTESALAKMDDLQRK
                     IYALVVKTTVAMFLPDYLYEETKIQTKVANLLFQSIGKTPKQEGWKILFKQQTKEEKED
                     VQTLPLVIIGEHAEVDVKSAEKETQPPKAFTEGTLLTAMKTANKTVDDEEAIKILQEVE
                     GIGTEATRASIIEALKQKEYIQVIKNKLVVTEKGKLLCQAVESQHLLTSAEMTAKWETY
                     LKKIGKREGNQENFITNIKKFIVHLLEAVPNDIEKLNFSDYQEQKEKEAEKSIVGKCPK
                     CGNNIVLKKSFYGCSNYPECKFTLAEHFRKKKLTKTNVKELLEGKETLVKGIKTKDKKS
                     YNAVVKIGEKGYIDFISFSK"
                     /name="type IA DNA topoisomerase"
     gene            complement(9074..9691)
                     /locus_tag="NP948_RS14855"
     CDS             complement(9074..9691)
                     /locus_tag="NP948_RS14855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_128712832.1"
                     /translation="MAKIGYARVSSKEQNLDRQLKALEGVSKVFSDKLSGQSVERPQLQ
                     AMLNYIREGDIVVVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENLRR
                     LINNLVIELYKYQAESERKRIKERQAQGIEIAKKKGKFKGRQPKFKENDPRLQHAFDLF
                     LNGLSDKEVEEQTGINRRTFRRYRARYNVTVDQRKNNEKRDS"
                     /name="recombinase family protein"
     gene            complement(9705..9875)
                     /locus_tag="NP948_RS14860"
     CDS             complement(9705..9875)
                     /locus_tag="NP948_RS14860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_164742224.1"
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEQVA
                     LADWLLQPREF"
                     /name="hypothetical protein"
     gene            complement(10223..11713)
                     /locus_tag="NP948_RS14865"
     CDS             complement(10223..11713)
                     /locus_tag="NP948_RS14865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="WP_256969073.1"
                     /translation="MNIPFVVETVLHDGLLKYKFKNSKIRSIITKPGKSKGAIFAYRSK
                     SSMIGGRGVVLTSEEAIHENQDTFTHWTPNVYRYGTYADENRSYTKGHSENNLRQINTF
                     FIDFDIHTEKETISASDILTTAIDLGFMPTLIIKSDKGYQAYFVLETPVYVTSKSEFKS
                     VKAAKIISQNIREYFGKSLPVDLTCNHFGIARIPRTDNVEFFDPNYRYSFKEWQDWSFK
                     QTDNKGFTRSSLTVLSGTEGKKQVDEPWFNLLLHETKFSGEKGLVGRNSVMFTLSLAYF
                     SSGYSIETCEYNMFEFNNRLDQPLEEKEVIKIVRSAYSENYQGANREYITILCKAWVSS
                     DLTSKDLFVRQGWFKFKKKRSERQRVHLSEWKEDLMAYISEKSDVYKPYLVTTKKEIRE
                     ALGIPERTLDKLLKVLKANQEIFFKIKSGRNGGIQLASVKSLLLSIIKLKKEERESYIK
                     ALTASFNLERTFIQETLNKLAERPKTDTQLDLFSYDTG"
                     /name="primase C-terminal domain-containing protein"
     gene            complement(12097..12369)
                     /locus_tag="NP948_RS14870"
     CDS             complement(12097..12369)
                     /locus_tag="NP948_RS14870"
                     /function="plasmid copy number control"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325780.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_011266100.1"
                     /translation="MELAFRESLKKMRGTKSKEKFSQELEMSRSNYSRIESGKSDPTIK
                     TLEQIAKLTNSTLVVDLIPNEPTEPESEQVTLDLEMEEEKSNDFV"
                     /name="helix-turn-helix transcriptional regulator"
     gene            12785..12979
                     /locus_tag="NP948_RS14875"
     CDS             12785..12979
                     /locus_tag="NP948_RS14875"
                     /inference="COORDINATES: protein motif:HMM:NF012798.2"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA];
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_194187778.1"
                     /translation="MTEISVHGFRHSHASLLFEAGLDVKSVQDRLGHSDVQTTLQIYTH
                     VTEKMKNNSGEKFQKYVNF"
                     /name="tyrosine-type recombinase/integrase"
     ARG             complement(13208..14388)
                     /name="cfr(D)"
                     /gene="cfr(D)"
                     /gene_name="Cfr 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="lincosamide antibiotic; streptogramin
                     antibiotic; oxazolidinone antibiotic; glycopeptide
                     antibiotic; phenicol antibiotic"
                     /identity="99.72"
                     /coverage="110.08"
     ARG             complement(13211..14280)
                     /name="cfr(D)"
                     /gene="cfr(D)"
                     /gene_name="23S rRNA (adenine(2503)-C(8))-methyltransferase
                     Cfr(D)"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL/LINCOSAMIDE/OXAZOLIDINONE/PLEUROMUTIL
                     IN/STREPTOGRAMIN"
                     /identity="99.72"
                     /coverage="100.0"
     gene            complement(14407..16041)
                     /locus_tag="NP948_RS14885"
     CDS             complement(14407..16041)
                     /locus_tag="NP948_RS14885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002588781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein PoxtA2"
                     /protein_id="WP_209691075.1"
                     /translation="MKGKNMNLAFGLEEIYEDAEFQIGDLDKVGIVGVNGAGKTTLFRL
                     LLGELELDNGSLTSGNARIGYLPQEIVLEDEDITVWDFLFEGRPIKKYEQELEEIYKKL
                     ETAVNAEQEALLARMGTLQERLEYFDFYEAETILLEFADKMSIDAELYHRPMRELSGGQ
                     KSKMAFARLLYSKPEILLLDEPTNHLDVSTKDFVIKYLKNYRGSVLIISHDIDFLNRII
                     NKIMYINKATHKISVYDGDYYIYKKKYAEEQRIREMAIVQQEKEIKELSDFVQKAKQAS
                     QTNHHLKRMGQERALRLDKKRGELQKRNRLYKRVKMDIRPKREGAQVPLEVENITFHYS
                     GYPTLYQNLSFQINGRERFLVVGENGVGKSTLLKLMMGILSPDEGCIRFNQKTDIAYYA
                     QELEQLDENKTVIDNVESEGYTPWQIRAVLSNFLFYDDDVNKKVSVLSPGEKARVALCK
                     ILLQKANLLILDEPTNHLDPETQKIIGGNFNLFEGTIIAVSHNPSFVEQIGISRMLILP
                     SGRIEPYSRELLEYYYEINTPEEEQKY"
                     /name="ABC-F type ribosomal protection protein PoxtA2"
     gene            16215..16895
                     /locus_tag="NP948_RS14890"
     CDS             16215..16895
                     /locus_tag="NP948_RS14890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_013646119.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(16979..18406)
                     /gene="fexA"
                     /locus_tag="NP948_RS14895"
     ARG             complement(16983..18406)
                     /name="fexA"
                     /gene="fexA"
                     /gene_name="chloramphenicol/florfenicol efflux MFS
                     transporter FexA"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL"
                     /identity="98.95"
                     /coverage="100.0"
     gene            complement(18660..18803)
                     /locus_tag="NP948_RS14900"
     CDS             complement(18660..18803)
                     /locus_tag="NP948_RS14900"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002360221.1"
                     /translation="MGIDFINVEFRKHVKVSGDLGTTGSVCPFSQKQKMETLPENFLPP
                     FI"
                     /name="hypothetical protein"
     gene            19284..19382
                     /locus_tag="NP948_RS14905"
     CDS             19284..19382
                     /locus_tag="NP948_RS14905"
                     /inference="COORDINATES: protein motif:HMM:NF015935.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="WP_086131521.1"
                     /translation="MKEAGDLLGISLLDHLVVTSNRYYSFRENGGL"
                     /name="JAB domain-containing protein"
     gene            19514..20194
                     /locus_tag="NP948_RS14910"
     CDS             19514..20194
                     /locus_tag="NP948_RS14910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_013646119.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(20758..>21165)
                     /locus_tag="NP948_RS14915"
                     /pseudo=""
     CDS             complement(20758..>21165)
                     /locus_tag="NP948_RS14915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /name="toxin zeta"
     ARG             complement(14411..16041)
                     /name="poxtA2"
                     /gene="poxtA2"
                     /gene_name="ABC-F type ribosomal protection protein PoxtA2"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL/OXAZOLIDINONE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(14408..16026)
                     /name="poxtA"
                     /gene="poxtA"
                     /gene_name="Miscellaneous ABC-F subfamily ATP-binding
                     cassette ribosomal protection proteins"
                     /tool="rgi"
                     /drug_class="tetracycline antibiotic; oxazolidinone
                     antibiotic; phenicol antibiotic"
                     /identity="100.0"
                     /coverage="99.45"
     Typing          complement(10224..11713)
                     /name="Inc18"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.732"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 cttttgccca tttttctatt gcaacttctt tagcatactt ggcttcttgt gattcttgag
       61 catcagacac gaacataagg gaattatcaa tgtctcccat atattcaagg tatttttgta
      121 cgtcatcatc aaaatcgata tttgagctat agttagcgag aacatgcttg attttttcta
      181 attcattttt attaatatca ataaaacgtc ccgctccacg caaagaaatt aacatggtca
      241 atctgagctt tcgaataact tcgtctgggg tttccaaaat aattttatca aatttataat
      301 ctctcttttt ctgctctatg aaatctacag tagctggtgc aatagtatca tttggcgtag
      361 aatcatctaa taggttcata gcatattcat aaaccaattc atttgaagtg ttatagccaa
      421 acttaactct gaattggtaa atatattctg ctaatgtttg atagtcatcg tttccccaag
      481 taataataaa tggtagatct tgtttcgaga tgccgggacg ttggtatttt tcatccaaat
      541 aatttattac attcaatacc aatgggaaaa agtttacctt gatagtattg cttctatacg
      601 gattgttaac ttgatatttc gagaacgcat ttaagaacgc tgactgttca aatgattcat
      661 cataggtatc tttgattgga tatccatttg aatattcatg aatcattaat ttcccatttt
      721 tcgaaataat tatcttttcc cctttgacaa ctcgaacaaa tccgagctca tttaaaaagt
      781 taaattgagt atgaattctg gattcccaac cacctttcca cccacgatct ttatgtgctg
      841 tgattgtatt ttccaacaga tatgttattt tttcgagagg aacactccca ggcgaaccct
      901 tttcccactg aatatatatt tcttcgacct tagaagcagc ttcctcggat tggtccgcag
      961 caacaaaatg aaatttttta ttatattcct tcatatatgt acctagggtc gctttagttg
     1021 gttcaaaaat cttttgccga attatttctc cttccaactc tagagctaac ttatcatcaa
     1081 taactttccc ctcaaattca ctgagaaccg agataaattg cggtattcta cctgggtttc
     1141 ttaaagttgt atcaaatgta attggctttc ttcttcttac tctcgacata cactcttctc
     1201 cttaccaaat aaatattaaa aagtgaggaa gagaccacat caaatgtgtg gcactctaat
     1261 tccgaaactc taaatctaaa ttactcatag gtgtaatttg taatataaat ctctttacta
     1321 tcttttttta tcgtattatc gaatcgggaa atataattac ttttgatgtc atactcatta
     1381 tatttttttc cccattcgag caaaatttca ttagtctttc ctttgtgatt atacatattg
     1441 gaaagccccc actttatccc cttcgaatca agttcatcca aaagcttgta taatctccgc
     1501 tcttcatctt ctccccaaag cttattgtag tcgctaaagg taatcagata cggcggatcg
     1561 aaataaagga aatcaccatt cttaaaatca taaaaattta caaaatcctc aaaatccatt
     1621 ccacttgaaa tctcaatgtt attgttgtta taccattggg aatagtttct aagtgcagtt
     1681 gaaacatttt tattccagtc aacattaccg acgggaagat tgaactgtcc ctgaccattg
     1741 aaacgtatca tgtggttgaa gccatatatg aggaggagat acaaaagcat ggtgttagac
     1801 tgatttttat tgtagtcatc cctgagtttt aagtaagcct gcttattgta tttggcaaaa
     1861 tacgttttct taaactcctt tttcaattct tcaatttcac tgtttttccc taattccgaa
     1921 agactcaaac cgtattctct aataagttcg tacatattct caataaataa ctcaatgtca
     1981 ctggattgct cttgtaaaaa tctatggagc tcaactacct tttcgtcaac atcattcata
     2041 ataattttat cagctatgac attgattgaa gcactccccc ctccagaaaa cacatcataa
     2101 taattattta tgtttttagg aaaaagttct ttcaactgcg gcatcaattt atacttatca
     2161 cctacgtaga ataacggtga acgaatagct tttccttttt ttttcatggg cgcaacaacc
     2221 tcgagtgttt cagtgggaaa taatgtcgtt tgcattattt tcctacctcc gttataaaga
     2281 cgaattcttt atgatccttt aaatctgtct ttcctgcatt aaagaattga aaaggcatct
     2341 cgaaagattt agtttttcca accttgttca aagattccaa tatttcatca tgtgtaatct
     2401 tattttttga actagaactt ttcgatttat aagtattgtt atacgtaaca acaatatact
     2461 tgacgtcaag attttgaatt aaatcatcaa acacttttgg cgctgaagaa cggctataat
     2521 cgctcatatt ttcagcaggt ggcttcattg caacaccgcc taattctggc ttgtcccatt
     2581 tcgcgattcc ctctaaaaca tggtaaaagc gagagtattg cctagaattg tacggtggat
     2641 cgataaacgc cacatcccct gatatttttc gaactaactc atttgaatct tctctgaaaa
     2701 tctgtatatc tttactcgaa gtatcaagag gatttaccag ctcaaattta aacctatcag
     2761 ctatttgtac tttttttcta taggcatcgt aatgcccaac ggtatttgct attttatcgc
     2821 tcgagtaaat aagtgatgct atcagtattg ctcgttcttt ttcagtcaat gatttatctt
     2881 tttcaattct tgttcgtatc tcacctataa cctttgcatc atgaacactg aaaaacttcc
     2941 cgccaaaatt atcagaaaag taatcgtcgt cctctttgtt cgtaattatg cgattgaact
     3001 cctcttgacg agagagcaac ttatttgaat caaacgaatc attactaaag aaagctttat
     3061 agataatatt attggaaaac agaaaatcat tcataatgaa agaatcatat tttccaagca
     3121 tctcttttga taccacccct gttccagcaa aaacatcaaa aaatgaatta ccttcagtgt
     3181 gcgcatcaat tagatcacta atccaattta ataacttatt tttatttcca atataccttc
     3241 gattttctag gttatatcta cctagaggtg cgaaattatc cgcttgttct ttcaaagctt
     3301 ccaattcttg cataacaaca tgtcgctcct taccaaccgt cctggcaatc gcatcaaaat
     3361 gcgtaacgct ccacttcgaa aagtcgcgtt tgttgattcc tcttactgtt gtttctggaa
     3421 tgcccgatac aatatgcatt tgtctaatat ttgtattatt attcttcaga taagtctcta
     3481 gtaacatttc tttcacctct tatcgttata ttataccacc tattttccat cttaacaacg
     3541 ttttttcgtt tattcgatgg ttgcgccgaa gaacaaaaaa ccttttgacg agttcaatct
     3601 tcaaaaggga atcaaaaaac tcccattcac aataaaaatg agcgaaaaac gcagattaac
     3661 cggttctgtt gcaaagtttt aaatctacta tcaaataagg tagaatatta gaaaaagata
     3721 gcaggaggaa tgacgatgaa tcattttaaa ggcaaacaat tcaaaaaatg acgtcattat
     3781 tgttgctgtt agttactacc tgcgttacaa tctaagctat cgtgaagttc aggaattgtt
     3841 atatgatcgt ggaataaatg tttgtcatac gacgatttat cgttgggtgc aagaatatgg
     3901 caaactactt tatcaaattt ggaaaaagaa aaataaaaaa tccttttatt catggaaaat
     3961 ggatgaaacg tacatcaaaa ttaaaggaaa atggcattat ttgtatcgag ccatcgatgc
     4021 agatggttta accttggata tttggttacg taaaaaacgg gacacacaag cagcgtatgc
     4081 ttttcttaag cggttagtga agcagtttga tgaaccgaag gttgtagtca cagataaagc
     4141 cccctctatt acaagtgcct ttaagaaact aaaagaatac ggcggctttt atcaagggat
     4201 agaacatcgt accattaaat acctgaataa tttgattgaa caagaccatc gtccagtaaa
     4261 gagacgcaat aaattctatc gaagtttacg cactgcctca cccacgatta aaggcatgga
     4321 agccattcga ggattatata agaaaacccg aaaagaaggc actctcttcg ggttttcggt
     4381 ctgtactgaa atcaaggtat tattgggaat cccagcttaa atcatagata ccgtaaggga
     4441 ttttattctt tatttaaaac tttgcaacag aaccttttaa ggtttaaagt cctggaagct
     4501 taggtatttt tggtattggt ggtgtaggtg gctgcaagct ttccaatttt tgttgaattg
     4561 ctttaaattc aggggtttct tggtgttgat tttgaaccat tttttgctct attctctcca
     4621 aagtcggttg aatttctttc cctgatactt tacgatttaa ttctctttct aaggtctctt
     4681 tcggactaat ggaaggcgtt tctaagcttg aatagagttt cactccttct ctattgtaaa
     4741 gccttatatc gctaaataag cccgttttat gaagggtttc taaattggtc ggtaagtttt
     4801 tgacaacaat atcatgcgct tgttttggtg ttgccctagc tgtcattgga tcatctgcat
     4861 acatagtttc ataccgttca attgttccta aatatgagtt gattttcggt actgctatga
     4921 catacatttt tgtttcataa cctttggctt gtagcattgt tgcggtttga ataggaacgt
     4981 ctgttgttcg tcctgtacct tcaatcacta aattatagcc ttgatcgctt aaacggctta
     5041 tgatcgcttc tgtcatgcga ttagaataag gggtaacgtg ttttactacg tctttttcat
     5101 agagtttcac tagttcgtca aaatttgggt gctgttgttt gaacgtatca ttatcaatga
     5161 taacaacatt tccttgtgtt tcttcaaaaa ttgctgatcg caaactggtt ttccctgatc
     5221 ctggttgccc accaagtaaa aaagcggttg gcgattcaac cgcttttttt ccttgaatca
     5281 attcttctaa attatcattt aagcgattct caaattgttt gtcagtaaaa ttgactatat
     5341 ttgccatatt aagccacttt ctctttattc aaaacttgtt ttgagtaacg attcattgac
     5401 cgccaatact catgaacggc ttgtaattct tctaaagaat aatcaaaaag atttacacgt
     5461 tttgcaagct ttaattggtt taataaattg acttccaata attgagagtc atttttattt
     5521 aattcatggt tcaaaacata gtttaatact cgattataaa cacttgccga taactcatta
     5581 atgatttcaa tttcaaatgt tttttcatat gtaactgcca tttcattttc actcctttta
     5641 aagtttgtca ggtaaatatt tccgtatata ttcttctaag gcttgatcca taacttcttt
     5701 tacgtttccg ccattctttg ctgtttcgat ttttatgata tggtgcaagt cagcacgaac
     5761 acgaaccgtc ttatctccca ttatatcttt ttttgcactg attggtgtat catttcgttt
     5821 tgctttttgt gcgcctaaat ttcccacaat cactcacttc tttctatttc ttcttattct
     5881 tattttatca tcaacaatca caaatcacaa gtgatttgtg attaatcact tgtgatttgt
     5941 gattctattc tttttcgttt tctaattgaa tgattcgctc aagcatttca aaaaatacgt
     6001 tctcatacat ggataaaact tttttgtcat agcctttgtg ttctgtaatt ccgtttttag
     6061 accaggtact tactttatta cttcgcttga taatattttg gaaaaccaag ttatcttctt
     6121 tatgttgctt gtacagttct tccaggtttg attttatcgt tgcgctgtcc gtatcaacta
     6181 aataaggaac aaaaccgatc atatctagtc cagggttaaa ctgttcttgt aaatcaatca
     6241 aataggaaat atagttttga atgttgtttg tactttcttc ttctgcttgt aaagggatca
     6301 taacgtaatc acttgccacg attgcattat ttgtataaac gcttggcgtt ggtacagtat
     6361 caataataat gagatcatag tcacttttta aaggtgctaa aagagtagca agcaatctac
     6421 tttcattttc aaacgtccat gagcgagtta attttggcag taacatcaaa tcaaacgtgc
     6481 cagggatcaa gtctaaatta tcagtcaaat gaataataga agaagccaag tttccatttt
     6541 tcaagccttc ataaaaattg acacgtggca attctacctt aaatgttttt gctaagtctt
     6601 ttgtcaatgt tgcttgtaag tccttatcga tcattaaaac ttttaaatta aatttgtctg
     6661 tcaaataagc aaacatagtc gataattttg actttccaac accaccttta aaataattgt
     6721 ttaagataac aattgcttca tttttactgt ttaaaatacg tcttaattct tcaagtattt
     6781 ttagttcttc cttctccata actacgcccc attctttttt tgtatagtaa tattgtatca
     6841 ttaggaatca caaatcacaa gtgatttgtg atttgtgata agtgatttgt gattaatata
     6901 taaaagccct gtttaaaggg cttttatgct tattttgaaa aagagataaa atcaatatat
     6961 cccttttctc cgatttttac aacggcattg taggactttt tatctttcgt tttgattcct
     7021 tttaccaggg tttcttttcc ctctagtaat tcttttacat ttgttttggt gagttttttc
     7081 tttctaaaat gttcagctaa agtaaactta cattcaggat aatttgaaca accataaaac
     7141 gattttttta atacaatatt gttgccacac ttaggacatt ttcctacaat acttttttct
     7201 gcttcttttt ctttctgttc ctggtaatca gaaaaattta gtttttctat atcgttaggt
     7261 acagcttcca gtaaatgaac aatgaatttt ttgatattcg taataaagtt ctcttgattg
     7321 ccttctcttt taccgatttt ttttaaatac gtttcccatt tagccgtcat ttcagcactc
     7381 gttaaaaggt gctgactttc aactgcctgg cacaataatt ttcctttttc agttacaaca
     7441 agcttattct taatcacttg gatatattct ttttgtttca aggcttcaat aatgcttgct
     7501 cttgtcgctt ctgttccgat cccctcgact tcttgtaaaa tcttgattgc ttcttcatca
     7561 tcaaccgttt tattagcggt tttcatagca gttaataatg taccctctgt aaaagctttc
     7621 ggtggttgtg tttctttttc ggcactctta acgtcaacct cggcatgttc gccaatgata
     7681 accaagggta acgtttgaac gtcctctttt tcttctttgg tttgttgttt gaaaagaatt
     7741 ttccaacctt cttgttttgg tgtctttccg atcgattgaa acagcaaatt agctactttc
     7801 gtttgtatct tggtttcttc atacaagtaa tcaggtaaaa acatggcaac ggtcgtttta
     7861 acgactaaag cataaatttt tcgttgtaaa tcgtccattt tcgctaatgc agattcggta
     7921 ggtacttgtt ttgttgggat aatggcgtgg tgttcctgta ccttactacc gtccacataa
     7981 cgctttctag gctctgtttg aaccatttca aggtcaagtc ctaaaaaacc gctatatttg
     8041 ccaaaattcg cttttaaata agcaaattcg ttctctgtaa taaatggggt atctgttctt
     8101 ggataactca ataattttgc ttcatacagt ccttgcatag cttttaaagt ttggctcgct
     8161 gtcgctttat aaagctgatt gacttttgat tgcaaactac ttaaagaaaa cagactcgga
     8221 ctattcgttt ttttctcttt ggtttgcacg tcagcgattc tgccctcttg attgcctatt
     8281 ttagcttgtt tagaagaaac aaaagctaaa agctcctctt gggttttaaa acgctgtgtg
     8341 gggcttagaa cgcccttaaa tgacccttgg tttactttta tactagcttc cacctcaaaa
     8401 aaaggttctt ttttaaaatt ctctatggct tcctggcgtt gataaatgag atataaagtc
     8461 ggtgtttgta cacgtcctaa agaaaatgta ccttgtacgc ctttttgttg taaattcaag
     8521 gtatataaag ggcttgcgtt catgccgatc aaccaatcag caatttggcg tgtttgcgct
     8581 tcttgataaa agggatagta attcattcct ggttgcaaat tttgaaaacc gcttcggatc
     8641 acatcttttt ctaagctatt gatccatagt cttttaaatg ttttatcttt tgaaaaggca
     8701 tttgctttat ggataatcga ccaggcgata ttttcacctt ctctgtcgct atctgttgca
     8761 acaataattg tatttgcttg ttttaaaagt ttggcaacga tcttaaactg ctttccctta
     8821 tcttttgcaa cttcaaaatc gtatcgatca ggaaaaatcg gcaaagattc aagtttccaa
     8881 ttttgccact tttcgtcata atgacctggt tctgctaatt ccactaaatg cccaaaacca
     8941 aaggtgataa acgtttcatc tgtaaatagt gggtctgtga tctcaaaata accgtctttt
     9001 ttggtgcttt gttttaaagc acttgcgtag gctaatgcct ggctcggttt ttcagctaaa
     9061 ataaccgtac tcattaacta tccctctttt cattgttttt tctttgatct acggtcacgt
     9121 tatatcttgc tcgatacctt ctaaacgttc ggcgattgat tccagtttgt tcttcaactt
     9181 ctttatcgga taaaccattc aaaaacaaat cgaaagcgtg ttgtaaacgt ggatcatttt
     9241 ctttgaattt aggttgtcgc cctttgaatt ttcctttttt cttagcaatt tcaattcctt
     9301 gggcttggcg ttctttaatt cgtttgcgtt cagattccgc ttggtactta tacaattcaa
     9361 tcactaaatt attaatcagc cgtcttaaat tttcatcttc aataccattc attgagggta
     9421 aatttaagac ttccagggtt gcccccttaa tttgaatttg attcatcaat tctgttaatt
     9481 ctttattatt tcgtcctaat cgatctaatt cagtaacaac aactatatcc ccttcacgaa
     9541 tatagttaag catagcttgt aattgtgggc gttcgaccga ttgaccgctt aatttgtctg
     9601 aaaagacctt agaaacgccc tctaacgctt tcagttgtct atctaagttc tgttctttgc
     9661 tactgacacg tgcataacca attttagcca ttttcaacca acctctaaaa ttctctcggt
     9721 tgcaataacc aatctgcaag tgctacttgt tcaatttcaa attgcttatc agaaattgtc
     9781 ttttcataag cgataaaatc ttgcgcatat tgttgctcat taaaaatagc caccacttcg
     9841 tcattttcta aaactcgata aataaatttt ttcattttac tcctcctatt atgcccaact
     9901 taaatgacct attcaataaa tctattatac tgctaaaacc atattaggac aaataagtat
     9961 actctaatga cctataaaag atagaaactt aaaaaatcaa gtgttcgctt cgctctcact
    10021 gcccctcgac gttttagtag cctttccctc acttcgttca gtccaagcca actaaaagtt
    10081 ttcgggctac tctctccttc tccccctaat aattaattaa aatcttactc tctatatttc
    10141 tgctaatcat tcactaaaca gcaaagaaaa aacaaacacg tatcatagat ataaatgtaa
    10201 tggcatagtg cgggttttat tttcagcctg tatcgtagct aaacaaatcg agttgtgtgt
    10261 ccgttttggg gcgttctgcc aatttgttta gagtttcttg aataaatgta cgttctaaat
    10321 taaacgaagc tgtcagcgcc tttatatagc tttctcgttc ttcttttttt aatttaatga
    10381 tcgatagcaa caatgattta acactagcaa gttgaatacc accatttctt cctgatttaa
    10441 tcttaaagaa aatttcctgg ttcgccttca gtaccttcag caatttatct aatgtccgtt
    10501 caggaatgcc tagcgcttct ctaatctctt ttttagtcgt cactaaataa ggcttgtata
    10561 catcgctttt ttcgctaata taagccatta aatcttcttt ccattctgac aaatgaacac
    10621 gttgacgttc gcttcttttt ttcttgaatt taaaccaccc ttgacggaca aataaatctt
    10681 tactggttaa atcacttgat acccaagctt tgcaaagaat ggtaatgtat tccctattag
    10741 ccccttgata gttttctgaa taggcacttc taacaatttt gattacttct ttttcttcta
    10801 agggttgatc taatcgatta ttaaactcaa acatattata ttcgcacgtt tcgattgaat
    10861 agcctgaact aaagtaggct aaagagaggg taaacataac gctattgcgc cctactaaac
    10921 ccttttctcc tgaaaatttc gtttcgtgca ataagagatt aaaccagggt tcatctactt
    10981 gttttttgcc ttctgtaccg cttaaaaccg ttagacttga acgagtaaag cccttattat
    11041 ctgtttgttt gaaagaccaa tcttgccatt ctttgaaaga ataacggtaa ttgggatcaa
    11101 aaaattctac attgtccgtt cttggtatac gagcaatccc aaaatgattg cacgttagat
    11161 caactggcaa agactttcca aaatattctc ggatattttg cgagattatt ttggctgctt
    11221 tgacagattt aaattctgat tttgaagtca catagactgg cgtttctaaa acaaaatatg
    11281 cttgataacc tttatcagat ttgataatta acgtaggcat aaaacctaaa tcaatagctg
    11341 ttgttaaaat atcgcttgct gaaatagttt ctttttccgt gtgaatatca aaatcaataa
    11401 agaaggtatt gatttgtctt aaattgtttt cagaatgtcc tttagtgtat gaacggtttt
    11461 cgtctgcata cgtaccataa cgataaacgt ttggtgtcca atgtgtaaat gtatcttgat
    11521 tttcgtgaat cgcttcttcg gaagtcagaa caacgccacg tccgccaatc atgcttgatt
    11581 ttgagcgata cgcaaaaata gcccctttgc ttttacctgg cttggtaatg attgagcgaa
    11641 ttttactatt tttaaatttg tactttaaca agccgtcatg aagcacagtt tctacaacaa
    11701 aagggatatt cattcagctg ttctcctttc ttacgaaaat taattagtta gaagctacga
    11761 tcaaagttga atcacaacaa aaaaggcaat caactaagtt tttcttaatt gattgcctgg
    11821 tatcttctta aagacttgaa atcccctcaa aaacccgata taatgggttt acagatattt
    11881 aagtatctga ttaataaagt aattaaatac tttaccaaat tttgggtctc gacttcttta
    11941 attgattggt ggtaatcaat taaggctcgc aacttatttt cttggcggaa aataagttgg
    12001 tcgtggctct ttttttgtat tctttattca gttcgttgtt tcgttatatc tagtatatcg
    12061 ctttttaaaa aaataagcaa tgatttcgtg cgttttttac acgaaatcat tgcttttttc
    12121 ttcttccatt tctaaatcca atgttacttg ttctgattct ggttctgttg gctcatttgg
    12181 gattaaatcc actactagcg ttgagttagt taactttgca atttgttcta gtgtttttat
    12241 ggttggatct gattttcctg attctattcg tgaataattt gatctactca tttctaattc
    12301 ttgggagaat ttttcttttg atttggtacc tctcatcttt tttaagcttt ctctaaatgc
    12361 tagttccaag tttctccccc ctctttttgt gtaataaaat tcacgcttta ttttaaatta
    12421 tagcttttaa tatcttaata aacaagtgat taatcacttg tgatttgtga ttaatcactt
    12481 gtgatttgtg attattccaa aagtaggtaa tttcaccaac ctttttcaaa agtttttatc
    12541 gacgattatt ggactggatc gtgtttccta aagcgattct aagcgctcgg gaccccattt
    12601 agaaaaagca ggaaaatgaa atggtaccat aaacggtcgt ttatggtacc attcaaattt
    12661 atccttattg tacaaaataa cagcgaaatt tttaaatcta ttccttatcg atacaaattc
    12721 ccactaagcg ctcgggaccc ctataccaaa tagagaacta aaaaaaatcg ttgataaata
    12781 taagatgact gaaatatcag tacatggttt tcgtcattct catgctagtt tattatttga
    12841 agctggtctt gatgttaaat ctgttcagga tagattagga cattctgatg ttcagactac
    12901 tttacagata tatactcatg taacagaaaa aatgaaaaat aattcaggtg aaaaattcca
    12961 aaagtatgtc aatttttagc aaatggcatt aactatggca ttaattccaa ttcatagcat
    13021 ggtttaaata acgataaaac aacataaaaa cattgataaa tagccatttg cctctataaa
    13081 aatatcatgg taaaattact gtgcaactat agagtgggaa taatttaaaa aagtaccgaa
    13141 taatctaatt atggattatt cggtactttt tagttatcca actaatttaa ttaaatgaga
    13201 aacaatctag tcatttactt ggattgtttt tttgttttta atctcataat ttccatataa
    13261 ttggccacag gcagcatcaa tttcaattcc aaactgactt ctaatagtga cttttatgcc
    13321 tttagatatt aaggtttgat agaacagttt aacttgcttt tcatctactt gcttgaacgt
    13381 tcttggtgca tcaaaagtag gattgtacct gatgagattg acatgataca gctttccttt
    13441 tttataccga gagcgaagta aatctgctaa agcaactgca tgagtcaaag aatcgttcac
    13501 atcaggtagt aaaatataag caatgtaaac tttttttgaa gttactttta tatgttcatc
    13561 taaagtatcc atcactttta aaaggggaaa acttttatta atcggcatta actgacttct
    13621 ctcttcatca aaaggtgagt gaagagaaaa agttaaatga acttgtggat attcagctgt
    13681 tagtcgtttt attttaggaa tcacaccaat cgttgaaaca gataaacgcc tagggctcag
    13741 ttgaaacata tcaggattca taaaaatatc taaagcctca aaaaaatgag ggttagcaag
    13801 tggttctccc atacccataa aagaaatact atcaatttgg tgtcctttta aaagaaagta
    13861 gagaacttga tccgttattt cctcagccgt taaatttttt cttaagccaa tttttccagt
    13921 agcgcaaaat tgacaaccta gattgcagcc acattgagat gaaatacaaa aagattccca
    13981 gccagcttga taggtcatgt tgactgtttc aatgcgatta tctccagaaa gattaaagag
    14041 tactttcctc acttgttgcg acttctgttc aataaggggc tcaactgtta gaagtgatgt
    14101 tcctatttct gttgttaaag tatctcgtaa atttttaggt aatacagaca tctcattgaa
    14161 atctgttttt ttctctttaa aaatacaatg aagaatttgc ttcattcggt agtttggttg
    14221 ttgacactct tttaaaactt tttcaatttg ttgatattta gttaattgtt tttgtaacat
    14281 attataaacc ctctcacgtt ctcttttttt atgagtaatg agaaggagta tggacaatat
    14341 ttcatacgcc ttttcattca taaatataaa actttgcaac agaaccaagt aaatcgttgc
    14401 ttttcattag tatttctgtt cttcttcggg agtgttgatt tcataataat actcaagcag
    14461 ctcacgggaa tagggttcaa ttcgaccgct gggcaaaata agcatacggc taattccgat
    14521 ttgttccaca aaggatgggt tatggctaac ggcaataatg gttccctcaa acaaattgaa
    14581 gttgccgcca atgattttct gcgtttctgg gtcaaggtgg ttggtcggct cgtccagtat
    14641 caaaagattg gctttctgta ataggatttt gcaaagggca acccttgctt tttctccagg
    14701 ggacagcaca gatactttct tgtttacatc gtcatcataa aacaggaagt tgctcagtac
    14761 ggctctgatt tgccacggtg tatatccttc agactccaca ttgtcaatga ccgttttgtt
    14821 ttcatcaagc tgttcgagtt cctgtgcata atatgcaata tcagttttct ggttaaagcg
    14881 aatgcatcct tcatctggac tgagaatacc catcatcaat ttcaataagg tggatttacc
    14941 gacaccgttt tcacccacca caagaaatcg ttctcttccg ttaatctgaa aggaaaggtt
    15001 ctgataaagg gtgggatacc ccgaatagtg gaaggtgata ttttccacct ctaagggaac
    15061 ttgtgcccct tcacgcttgg ggcgaatatc catcttcaca cgcttgtaca gtcgatttct
    15121 cttttgcagc tctccacgct ttttatcaag ccgcaaggct cgctcttgac ccattcgttt
    15181 gaggtgatga ttggtctgac tggcttgttt tgctttttgt acaaaatcgg aaagctcctt
    15241 tatttctttt tcctgctgta caatcgccat ttcacgaatc cgctgttcct ctgcatactt
    15301 tttcttgtag atgtagtagt ctccatcata aacagatatt ttatgggtag ctttgttgat
    15361 gtacataatt ttgttgataa tccgatttag aaaatcaata tcatggctga taatcagtac
    15421 cgaaccccta taattcttta agtattttat aacaaaatcc tttgtgctga catctaaatg
    15481 gttggtaggc tcatccaaca atagaatttc cggttttgaa tatagtagtc tggcaaatgc
    15541 cattttggat ttttgtccgc ctgaaagctc tctcatcgga cgatgatata attctgcatc
    15601 aatgctcatt ttatctgcaa actccaacag aattgtttct gcctcataga agtcgaaata
    15661 ctccaagcgt tcttgcaatg ttcccattcg ggcaagcagt gcttcctgct ctgcattgac
    15721 tgcggtttca agctttttat agatttcttc caattcctgc tcatactttt taatcggacg
    15781 tccctcaaaa aggaaatccc aaacggtaat atcctcatct tccaagacaa tttcctgtgg
    15841 gagataacca atacgggcat ttccactggt cagtgaacca ttatcaagtt caagttctcc
    15901 caacagcagg cggaacaagg tggtctttcc ggctccgttc acgccgacaa taccgacctt
    15961 atccaaatct ccgatttgaa actcagcatc ctcataaatt tcttccaacc caaaggctaa
    16021 attcatattt ttacctttca tcttgtatca ttcctccatc gtcatacata ctgcaagcca
    16081 tcattttatg gcttacagtt ttccttgctt gattatctcc tgtgcgggga tatattttct
    16141 ggttctgttg caaagtttta aatctactat caaataaggt agaataatag aaaaagatag
    16201 caggaggaat gacgatgaat cattttaaag gaaagcaatt tcagcaggat gtgattattg
    16261 tagccgtggg ctactatctt cgttataacc ttagctatcg tgaagttcaa gaaatcttat
    16321 atgatcgtgg cattaacgtt tctcatacga cgatttatcg ttgggtgcaa gaatatggca
    16381 aactactcta tcaaatttgg aaaaagaaaa ataaaaaatc cttttattca tggaaaatgg
    16441 atgaaacgta catcaaaatt aaaggaaaat ggcattattt gtatcgagcc atcgatgcag
    16501 atggtttaac cttggatatt tggttacgta aaaaacggga cacacaagca gcctatgctt
    16561 ttcttaagcg gttagtgaag cagtttgatg aaccgaaggt tgtagtcaca gataaagccc
    16621 cctctattac aagtgccttt aagaaactaa aagaatacgg cttttatcaa gggacagaac
    16681 atcgtaccat taaatacctg aataatttga ttgaacaaga ccatcgtcca gtaaagagac
    16741 gcaataaatt ctatcgaagt ttacgcactg cctcacccac gattaaaggc atggaagcca
    16801 tccgaggatt atataagaaa acccgaaaag aaggcactct cttcgggttt tcggtctgta
    16861 ctgaaatcaa ggtattattg ggaatcccag cttaaattat agataccgta agggatttta
    16921 ttctttattt aaaactttgc aacagaaccc aataactaat ctttacataa ctaagttatt
    16981 acccacgctt ttttaaacct aatccagcta ttaaggcaat gagtattgcc cctgtagctg
    17041 caaggaacgc atctgagtag gacatagcgt ccaatatata taatggattt atcggctcag
    17101 tagcatcacg tcgagcggat aataatgctc caatcatacc tgctccagtt cctgctccaa
    17161 ggtacaaagc accttggaaa atccccattc cgacaccaac cttgtctgca tcgagtgcac
    17221 ttactgcggc gttatttgcg ggagaattcg tgaatgcaaa agcaatccct actccgagga
    17281 cccccacgga aactaacaga ggtgaagcac cagatgcata ggtggacaag aataaggtag
    17341 acagccccat cagagtcatc ccagtaatta tcagacgttt atccccaaat cgatcagaaa
    17401 gacggccaac gaagggagat aagattgcaa cagccacacc acctggcaac aatatcattc
    17461 cagcctgtcc agaagagagt ccattcacct caatgactag taatgggacg aacacaagaa
    17521 cagcgaaata agcaaacatc gaaaaaaatg caattatgac cgtattgaca taatccttgt
    17581 tattgaacag gacaggtggt acaaatggat tttctgcggt aacaattctc caaataaatc
    17641 ccaccaaagc tacaacagaa ccaattaggc tagttaacga tgagaacgaa gaaaaaccag
    17701 aagtttctcc ttgagtgatg ccaaaaagga gtaatcctac tgtgaggccg aggaataaac
    17761 caccaatgaa atcaaagttc ttattgcttc ctacggattc tgccggttta attgtcggta
    17821 acgcgtagta ggcaccaata acaatcataa tggctaacaa aaatgtgaac caaaacaagg
    17881 cattccaccc taaatattga ccaactactc caccaaatat tggaccagca gcagttccaa
    17941 caccaatact tcctgcgata attcccaaag ctcccccacg ttttccttgt gggaaaacct
    18001 tcgaaattgc aatgactgat agaactggaa ttgcggacat cccagcaccc tgaaccattc
    18061 ttcccaaaac caacaatggg aggttcgggg caattgcaca taaaagacta ccacttgcca
    18121 gaatcataat ggcaaagata tatagctttc gtaactcaaa aaagtctgag attcgaccat
    18181 aaatcggaac tccaatcgca agaacaagtg caataccact aactatccaa ctcacttgag
    18241 atttcgaagc ttctaaagct ttgcttatta gtggaagtac gggattgact gaatcagccg
    18301 taattgaacc tacaagtaca gatagggaga gtaccatcat taaaagccta gtagaacccc
    18361 ttttttcaga ttgaatcatt tctttagatt tactatcctt tttcatttta tttcctccta
    18421 aaatatattg tgattttagg aggctaaatc cactgctttc accataaacc tcacctcata
    18481 tctatttata ttgtaaaacc aaatcaacga actcaccata tttctacagc atgattaaag
    18541 attcggttct ccaaactaac tgaactgatc aaacaaaaaa aaggcaccag tttaacaacc
    18601 ggtgcctaat cattcgtatg catttttaca aatgcaatag attcataaat ttttgcccat
    18661 tatataaaag gaggcaaaaa gttttccggt agtgtttcca ttttttgttt ttgtgaaaaa
    18721 ggacatactg atcccgttgt acctaaatcc cctgaaactt ttacatgctt tctaaactcg
    18781 acattaatga aatcaattcc cattactttt tgcctccttt ctcatattgt gataataaca
    18841 caattataat tgatgaaaaa gaaataatca accctacttt tttgaaaacc aatttaaagc
    18901 tttactactt ttacttacat aataaaggca ggtgcagtat aaactttttt aaataggtct
    18961 tctttaacga gcaggtagcg tcagttaaag tagataattt aagatcgaaa tcatattata
    19021 gatattccga aattgggcgt gattgttgca ggtcaaaagc ttaattcctc gataaaataa
    19081 aaaggaatta gtttttttat ttgtggtaca ttcttctgac cgtaatcaat tgtcatctaa
    19141 taattacatt gtattttttc atttgattta acacgttaaa tatatgttct taaagtaaaa
    19201 acattgatgt taatggattt ttagtaattt actcttgata aaatccgcaa ccaagtgaag
    19261 cagataaatt atttacagaa cgcatcaaag aagctggcga cctattagga atttccctac
    19321 tcgaccacct cgttgttacg agcaatcgtt actatagttt tcgagagaat ggcggattgt
    19381 agaaggaagc aaagcacagg ctcaaaaaga gcctgtggct ttgatgaaag gagaaaacag
    19441 gttctgttgc aaagttttaa atctactatc aaataaggta gaataataga aaaagatagc
    19501 aggaggaatg acgatgaatc attttaaagg aaagcaattt cagcaggatg tgattattgt
    19561 agccgtgggc tactatcttc gttataacct tagctatcgt gaagttcaag aaatcttata
    19621 tgatcgtggc attaacgttt ctcatacgac gatttatcgt tgggtgcaag aatatggcaa
    19681 actactctat caaatttgga aaaagaaaaa taaaaaatcc ttttattcat ggaaaatgga
    19741 tgaaacgtac atcaaaatta aaggaaaatg gcattatttg tatcgagcca tcgatgcaga
    19801 tggtttaacc ttggatattt ggttacgtaa aaaacgggac acacaagcag cctatgcttt
    19861 tcttaagcgg ttagtgaagc agtttgatga accgaaggtt gtagtcacag ataaagcccc
    19921 ctctattaca agtgccttta agaaactaaa agaatacggc ttttatcaag ggacagaaca
    19981 tcgtaccatt aaatacctga ataatttgat tgaacaagac catcgtccag taaagagacg
    20041 caataaattc tatcgaagtt tacgcactgc ctcacccacg attaaaggca tggaagccat
    20101 ccgaggatta tataagaaaa cccgaaaaga aggcactctc ttcgggtttt cggtctgtac
    20161 tgaaatcaag gtattattgg gaatcccagc ttaaattata gataccgtaa gggattttat
    20221 tctttattta aaactttgca acagaaccgc tgttcttgtg ttccaaaaaa ctcattttct
    20281 gtaaaatctt ctaattgtaa tttttttgtt ttttccattt tcttttcctc ttttcttttt
    20341 ttgattttta gttttttgac aaccattttt gttaggcgtt tgaggaagtg aagctgtttt
    20401 cctcatgttt taaaagctag aaataaatta cagtgtatgc tcctttcttt tttcgttttg
    20461 ttggttcatt ttcgccagtg tgttcgtgtc gtttgctgtg acgagaacgc aacatagaca
    20521 caaagaaaac acaagggcga gcttactcgt ttatataccc ttgtgttttc gactggatat
    20581 gttaaggtaa caaacagtaa atgacacgtt acagactgca aaatgtacca actgaaaaaa
    20641 gaaagaatac cgttgtgtgc tttatttctc gatcagcttt tcaaacatga ggaaaggttt
    20701 ttataaaaaa agagtagtta ccgttttttg gtaactactc ttttcctttt ttaaggttta
    20761 aagtcctgga agtctaggtg ttttgggtat tggtggtgta ggtcgctgca agctttccaa
    20821 tttttgttga attgctttaa attcaggggt ttcttagtgt ttatttagaa ccattttttg
    20881 ctctattcgt tctaaagtcg gttgaatttc tttacttgat actttacgat ttaattcttt
    20941 ttctaaggtt tcttttggac taatagaagg tgtttccaaa cttgaataga gtttcactcc
    21001 ttctctgtta tatagcctta tatcgctaaa taagcccgtt tttttaagca attctaaatt
    21061 gttaggtaga tttttaacaa caatatcatg tgcttgcttt ggtgttgccc tgtctgtcat
    21121 tggttcatct gcatacatag tttcataccg ttcaattgtt cctaaaggtt ctattcacag
    21181 gttcaaatgg gtgtgaatag acacgaattt tctttattta acctaaaaaa caggcatgct
    21241 ctgtggtttt acataattcc tgattttttt ataatctctt atggtgctaa ctcgttcaga
    21301 gtattcaacg aaatctttga tatcccaagg atatatttcg acaccattag tttgtttaat
    21361 caatgctact tgatccccaa catcacgggt tatattggat gcaataaaca ggctgaacca
    21421 ttctttaaaa ttattacctt cttcaacatc tttatttgca gtacctaata cgtgattacg
    21481 aattgaaggg agttcatgtt caacttggaa acttctttgt ttagaaatgg ttggttctaa
    21541 aatagcgtga atgttatctt cgaagacatc aatatccgca ccaattaggt tcctcttccc
    21601 accggatgcg gtgttaaatg gtattccttg atcatctgct ttataattag ctacaacctt
    21661 caatttaggt aaggcttttt taattacaat agctgaaagg aattccaatc tagcagtttc
    21721 tttcacatat tttaagatta aatgacttga aggacgtttt tcaacactat taaccatttc
    21781 ttcttttaag aacgtccagt catact
//
