LOCUS       NZ_CP101791            19016 bp    DNA     circular CON 15-AUG-2023
DEFINITION  Klebsiella pneumoniae strain hvKP859 plasmid unnamed1, complete
            sequence.
ACCESSION   NZ_CP101791
VERSION     NZ_CP101791.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN29889749
            Assembly: GCF_024496205.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 19016)
  AUTHORS   Wang,W., Luo,Y., Zi,C., Yang,S., Zhang,J. and Zhao,Z.
  TITLE     Hypervirulent Klebsiella pneumoniae 859 complete genome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 19016)
  AUTHORS   Wang,W., Luo,Y., Zi,C., Yang,S., Zhang,J. and Zhao,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUL-2022) Department of Microbiology and Immunology of
            Basical Medicine, Guangdong Medical University, No. 1, Xincheng
            Avenue, Songshan Lake, Dongguan City, Guangdong, Dongguan, Guangdong
            523808, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 15-JUN-2022
            Assembly Method                   :: ABySS v. 2.0.2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 08/15/2023 08:36:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,691
            CDSs (total)                      :: 5,565
            Genes (coding)                    :: 5,408
            CDSs (with protein)               :: 5,408
            Genes (RNA)                       :: 126
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 89
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 157
            CDSs (without protein)            :: 157
            Pseudo Genes (ambiguous residues) :: 0 of 157
            Pseudo Genes (frameshifted)       :: 73 of 157
            Pseudo Genes (incomplete)         :: 86 of 157
            Pseudo Genes (internal stop)      :: 38 of 157
            Pseudo Genes (multiple problems)  :: 36 of 157
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP101791.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..19016
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="hvKP859"
                     /isolation_source="sputum"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="unnamed1"
                     /geo_loc_name="China:Zhanjiang"
                     /collection_date="2022-04-16T16:28:27Z"
     gene            55..522
                     /locus_tag="NPJ86_RS25585"
                     /old_locus_tag="NPJ86_25585"
     CDS             55..522
                     /locus_tag="NPJ86_RS25585"
                     /old_locus_tag="NPJ86_25585"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_256546999.1"
                     /translation="MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLEV
                     CPKCDHHMRMSARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKETGE
                     KDALVVMKGTLYAMPVVAAAFEFSFMGDRWVPSSAHALYARWSRRWKITAR"
                     /name="hypothetical protein"
     gene            453..884
                     /locus_tag="NPJ86_RS25590"
                     /old_locus_tag="NPJ86_25590"
     CDS             453..884
                     /locus_tag="NPJ86_RS25590"
                     /old_locus_tag="NPJ86_25590"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="WP_256547000.1"
                     /translation="MGSVVGARFVRAVEQALEDNCPLICFSASGGARMQEALMSLMQMA
                     KTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNIAEPKALIGFAGPRVIEQTV
                     REKLPPGFQRSEFLIEKGAIDMIVRRPKCVSSWPAFWRS"
                     /name="carboxyl transferase domain-containing protein"
     gene            1048..2314
                     /gene="folC"
                     /locus_tag="NPJ86_RS25595"
                     /old_locus_tag="NPJ86_25595"
                     /pseudo=""
     CDS             1048..2314
                     /gene="folC"
                     /locus_tag="NPJ86_RS25595"
                     /old_locus_tag="NPJ86_25595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228074.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016874 - ligase activity [Evidence IEA]; GO:0004326 -
                     tetrahydrofolylpolyglutamate synthase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tetrahydrofolate
                     synthase/dihydrofolate synthase"
                     /name="folC"
     gene            2304..2993
                     /gene="dedD"
                     /locus_tag="NPJ86_RS25600"
                     /old_locus_tag="NPJ86_25600"
     CDS             2304..2993
                     /gene="dedD"
                     /locus_tag="NPJ86_RS25600"
                     /old_locus_tag="NPJ86_25600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004151102.1"
                     /GO_component="GO:0030428 - cell septum [Evidence IEA]"
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /GO_process="GO:0032506 - cytokinetic process [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DedD"
                     /protein_id="WP_004214089.1"
                     /translation="MASKFQNRLVGTIVLVALGVIILPGLLDGQKKHYQDEFAAIPLVP
                     KPGDRDEPDMLPAATQALPSQPPEGAAEEVRAGDAAAPSLDPSRIPVNSNSFDDVQEPV
                     VAAKPQPKPQPKPQPQQQAATPTPPPAKPQQQQPPQQQAALPAPTGKAYVVQLGALKNA
                     DKVNEIVGKLRASGFKVYTSPSTPVQGKITRILVGPDASKDKLKGQLGDLQQISGLSGV
                     VMGFTPN"
                     /name="dedD"
     gene            3210..3698
                     /gene="cvpA"
                     /locus_tag="NPJ86_RS25605"
                     /old_locus_tag="NPJ86_25605"
     CDS             3210..3698
                     /gene="cvpA"
                     /locus_tag="NPJ86_RS25605"
                     /old_locus_tag="NPJ86_25605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin V production protein"
                     /protein_id="WP_002913214.1"
                     /translation="MVWIDYAIMAVLGLSCLVSLIRGFVREALSLVTWGCAFYVASHYY
                     ADLSVWFTGFEDERVRNGIAIAALFIVTLIVGAIVNYVIGQLVEKTGLSGTDRVLGICF
                     GALRGVLIIAAILFFLDTFTGMAKSDDWHQSQFIPYFTPVIRWFFEYLQSSSSFLPKV"
                     /name="cvpA"
     gene            3732..5248
                     /gene="purF"
                     /locus_tag="NPJ86_RS25610"
                     /old_locus_tag="NPJ86_25610"
                     /pseudo=""
     CDS             3732..5248
                     /gene="purF"
                     /locus_tag="NPJ86_RS25610"
                     /old_locus_tag="NPJ86_25610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820991.1"
                     /GO_function="GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /name="purF"
     gene            5384..5953
                     /locus_tag="NPJ86_RS25615"
                     /old_locus_tag="NPJ86_25615"
     CDS             5384..5953
                     /locus_tag="NPJ86_RS25615"
                     /old_locus_tag="NPJ86_25615"
                     /EC_number="2.5.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228070.1"
                     /GO_function="GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]; GO:0106141 - flavin prenyltransferase activity
                     [Evidence IEA]; GO:0010181 - FMN binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="WP_002913212.1"
                     /translation="MKRLIIGISGASGAIYGVRMLQVLRDVPDIETHLILSQAARQTLA
                     METDYSVREVQALADVVHDARDIAASISSGSFKTAGMVILPCSMKTLSGIVHSYTDGLL
                     TRAADVVLKERRPLVLCVRETPFHLGHLRLLVQAAELGAVIMPPVPAFYHRPQSLDDVI
                     NQTVNRVLDQFDISLEHDLFTRWQGA"
                     /name="UbiX family flavin prenyltransferase"
     gene            complement(6034..6195)
                     /locus_tag="NPJ86_RS25620"
                     /old_locus_tag="NPJ86_25620"
     CDS             complement(6034..6195)
                     /locus_tag="NPJ86_RS25620"
                     /old_locus_tag="NPJ86_25620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004140952.1"
                     /translation="MVIADQSCSFCAIFPVRAGNRVKFVKIKLQDCLKREDTSITGETA
                     APERKKTK"
                     /name="hypothetical protein"
     gene            6236..7018
                     /gene="argT"
                     /locus_tag="NPJ86_RS25625"
                     /old_locus_tag="NPJ86_25625"
     CDS             6236..7018
                     /gene="argT"
                     /locus_tag="NPJ86_RS25625"
                     /old_locus_tag="NPJ86_25625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine/arginine/ornithine ABC transporter
                     substrate-binding protein ArgT"
                     /protein_id="WP_002913210.1"
                     /translation="MKKTILALSLLVGMSSTASVFAALPQSIRIGTDATYAPFSSKDAK
                     GDFVGFDIDLGNELCSRIKVKCTWVGSDFDSLIPSLKAKKIDAIISSLSITEKRQQEIA
                     FSDKLYAADSRLIAAKGSPIQPTLEALKGKHVGVLQGSTQEAYANDRWRSQGVDVVAYQ
                     NQDLIYSDLAAGRLDAALQDEVAASEGFLKQPAGKDFAFAGPSVKDKKYFGDGTGIGLR
                     KDDAELKAAFDKALGEMRKDGTYDKMAKKYFDFNVYGD"
                     /name="argT"
     gene            7286..8068
                     /gene="hisJ"
                     /locus_tag="NPJ86_RS25630"
                     /old_locus_tag="NPJ86_25630"
     CDS             7286..8068
                     /gene="hisJ"
                     /locus_tag="NPJ86_RS25630"
                     /old_locus_tag="NPJ86_25630"
                     /EC_number="7.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter substrate-binding
                     protein HisJ"
                     /protein_id="WP_002913209.1"
                     /translation="MKKLALSLSLALALSSVSTVFAAIPQKIRIGTDPTYAPFESKNAQ
                     GELVGFDIDLAKELCKRINTQCTFVENPLDALIPSLKAKKIDAIMSSLSITEKRQQEIA
                     FTDKLYAADSRLVVKKGSPVTPDLATLKGKRVGVLQGTTQETYGNEHWAPKGIEIVSYQ
                     GQDNIYSDLTAGRIDAAFQDEVAASEGFLKQPIGKDYQFGGPSIKDEKLFGVGTGMGLR
                     KEDNELREALNKAFAEMRKDGTYDKLAKKYFDFNVYGE"
                     /name="hisJ"
     gene            8133..8819
                     /locus_tag="NPJ86_RS25635"
                     /old_locus_tag="NPJ86_25635"
     CDS             8133..8819
                     /locus_tag="NPJ86_RS25635"
                     /old_locus_tag="NPJ86_25635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012124147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter permease HisQ"
                     /protein_id="WP_002913208.1"
                     /translation="MLYGFSQVILQGALVTLELALSSVVLAVLIGLAGAGAKLSSNRPL
                     ALVFEGYTTLIRGVPDLVLMLLIFYGLQIALNSVTDALGMAQFDIDPMIAGIITLGFIY
                     GAYFTETFRGAYLAVPKGHIEAATAFGFSGGQTFRRILFPAMMRYALPGIGNNWQVILK
                     ATALVSLLGLEDVVKATQLAGKSTWQPFYFAIVCGLIYLVFTTVSNGVLLLLERRYTVG
                     VKRADL"
                     /name="histidine ABC transporter permease HisQ"
     gene            8816..9532
                     /gene="hisM"
                     /locus_tag="NPJ86_RS25640"
                     /old_locus_tag="NPJ86_25640"
     CDS             8816..9532
                     /gene="hisM"
                     /locus_tag="NPJ86_RS25640"
                     /old_locus_tag="NPJ86_25640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter permease HisM"
                     /protein_id="WP_002913207.1"
                     /translation="MIEIIQEYWKSLLWTDGYRFTGVAITLWLLISSVVMGGILAVFLA
                     IGRVSSNKFIQFPIWLFTYIFRGTPLYVQLLVFYSGMYTLEIVKGTELLNAFFRSGLNC
                     TVLALTLNTCAYTTEIFAGAIRSVPAGEIEAARAYGFSSVKLYRCIILPSALRIALPAY
                     SNEVILMLHSTALAFTATVPDLLKIARDINSATYQPFTAFGIAAVLYLIISYVLISLFR
                     KAEKRWLQHIKPSSTH"
                     /name="hisM"
     gene            9540..10313
                     /gene="hisP"
                     /locus_tag="NPJ86_RS25645"
                     /old_locus_tag="NPJ86_25645"
     CDS             9540..10313
                     /gene="hisP"
                     /locus_tag="NPJ86_RS25645"
                     /old_locus_tag="NPJ86_25645"
                     /EC_number="7.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter ATP-binding protein
                     HisP"
                     /protein_id="WP_002913206.1"
                     /translation="MSDNKLNVIDLHKRYGEHEVLKGVSLQAKAGDVISIIGSSGSGKS
                     TFLRCINFLEKPSEGTIVVSGQNIGLVRDKDGQLKVADKNQLRLLRTRLTMVFQHFNLW
                     SHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDERQQAKYPVHLSGGQQQRVSI
                     ARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSSHV
                     IFLHQGKIEEEGHPDALFGAPKSPRLQQFLKGSLK"
                     /name="hisP"
     gene            complement(10319..10846)
                     /locus_tag="NPJ86_RS25650"
                     /old_locus_tag="NPJ86_25650"
     CDS             complement(10319..10846)
                     /locus_tag="NPJ86_RS25650"
                     /old_locus_tag="NPJ86_25650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228063.1"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_004140943.1"
                     /translation="MTTITTPRLSLTRFVTDDWPFFLRLRQDPQVMRFMGEVLSEEALR
                     SVFVSRCADPGVFVLRDKFGEALGDIGLRISPKNPHEADVGYALLPQAQGKGYASEALR
                     AVCEYGFTTLGVQAINAWVLGENRGSSRLLEKQGFVRTQVLEKAYHLNGVDYDDWIYRL
                     EREAHPASADAG"
                     /name="GNAT family N-acetyltransferase"
     gene            10966..11082
                     /locus_tag="NPJ86_RS25655"
                     /old_locus_tag="NPJ86_25655"
     CDS             10966..11082
                     /locus_tag="NPJ86_RS25655"
                     /old_locus_tag="NPJ86_25655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_161424709.1"
                     /translation="MAMLQRQGEAIQAWSTSQQNGIRGANAPLCQPLTQHIL"
                     /name="hypothetical protein"
     gene            complement(11062..11955)
                     /locus_tag="NPJ86_RS25660"
                     /old_locus_tag="NPJ86_25660"
     CDS             complement(11062..11955)
                     /locus_tag="NPJ86_RS25660"
                     /old_locus_tag="NPJ86_25660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228061.1"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01777 family oxidoreductase"
                     /protein_id="WP_096608795.1"
                     /translation="MKILLTGGTGLIGRHLIPRLLELGHSVTVSTRHPDTARARLDPRV
                     TLWRDFEGHHHLNDIDAVINLAGEPIADKRWTAEQKQRLCHSRWDLTQRLVGLIHASDT
                     PPSVLISGSAIGYYGDLGEVVVTEEEPPHNEFTHKLCARWEQIACEAQSERTRVCLLRT
                     GVVLAPRGGILGKMTPAFKLGLGGPIGNGRQYLAWIHIDDMVNGILWLLDNDLRGPFNM
                     VSPYPVHNEQFAHALGHALHRPAIFRVPAAAIRLLMGESAVLVLGGQRALPKRLEAAGF
                     AFRWYDLDETLKDVLS"
                     /name="TIGR01777 family oxidoreductase"
     gene            complement(11974..12336)
                     /gene="folX"
                     /locus_tag="NPJ86_RS25665"
                     /old_locus_tag="NPJ86_25665"
     CDS             complement(11974..12336)
                     /gene="folX"
                     /locus_tag="NPJ86_RS25665"
                     /old_locus_tag="NPJ86_25665"
                     /EC_number="5.1.99.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228060.1"
                     /GO_function="GO:0004150 - dihydroneopterin aldolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006760 - folic acid-containing compound
                     metabolic process [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate 2'-epimerase"
                     /protein_id="WP_002913200.1"
                     /translation="MSQPDAIIRIKNLRLRTFIGIKEEEIANRQDVVVNVAIHYPADKA
                     RDSEDINDALNYRTITKRIISHLENGRFSLLEKLTQDVLNIACEHHWVTYAEVEIDKLH
                     ALRYADSVSMTMSWRR"
                     /name="folX"
     gene            complement(12402..13031)
                     /gene="yfcG"
                     /locus_tag="NPJ86_RS25670"
                     /old_locus_tag="NPJ86_25670"
     CDS             complement(12402..13031)
                     /gene="yfcG"
                     /locus_tag="NPJ86_RS25670"
                     /old_locus_tag="NPJ86_25670"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GSH-dependent disulfide bond oxidoreductase"
                     /protein_id="WP_004174988.1"
                     /translation="MIDLYYAPTPNGHKITLFLEEAELAYRLIRVDIGKGEQFHPQFLA
                     ISPNNKVPAIVDHMPADGGAPLSVFESGAILLYLAEKSGKLLSGELRERYVTLQWLFWQ
                     VGGLGPMLGQNQHFSHSAPQTVPYAIERFQVETQRLYGVLNQRLGCSPWLGGDHYSIAD
                     IAAWPWVNCHVRQRIDLANYPAVHNWYERIKQRPATAEAMLKIQLY"
                     /name="yfcG"
     gene            13212..13850
                     /gene="yfcF"
                     /locus_tag="NPJ86_RS25675"
                     /old_locus_tag="NPJ86_25675"
     CDS             13212..13850
                     /gene="yfcF"
                     /locus_tag="NPJ86_RS25675"
                     /old_locus_tag="NPJ86_25675"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228058.1"
                     /GO_process="GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase"
                     /protein_id="WP_009307378.1"
                     /translation="MSQPVITLWSDADFFSPYVMSVYVALQEKSLPFTLKTVDLNRGEH
                     LQAGWTGYAATRRVPLLEVDDFALSESSAITEYLDERFAPPEWERIYPHDLQKRARARQ
                     IQAWLRSDLMPIREERSTAVVFGGAKMPDLSEAGRQSAEKLFATATMLLAHGGQNLFGE
                     WSIADADLALMLNRLVLNGDKVPEALADYASFQWQRASIQRYVALSAKR"
                     /name="yfcF"
     gene            13913..14464
                     /gene="yfcE"
                     /locus_tag="NPJ86_RS25680"
                     /old_locus_tag="NPJ86_25680"
     CDS             13913..14464
                     /gene="yfcE"
                     /locus_tag="NPJ86_RS25680"
                     /old_locus_tag="NPJ86_25680"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="WP_004899586.1"
                     /translation="MKLMFASDIHGSLPATERVLERFAQSGARWLIILGDVLNHGPRNA
                     LPEGYAPGEVAERLNSVAERIVAVRGNCDSEVDQMLLRFPITAPWQQVLSERYRLFLTH
                     GHLYSPDNLPPLAAGDVLAYGHTHIPVAEKRGAIYLFNPGSVSIPKGGYSASYGLLDQG
                     RLQVLALNDNQVIAEVAIYP"
                     /name="yfcE"
     gene            14522..15073
                     /gene="yfcD"
                     /locus_tag="NPJ86_RS25685"
                     /old_locus_tag="NPJ86_25685"
     CDS             14522..15073
                     /gene="yfcD"
                     /locus_tag="NPJ86_RS25685"
                     /old_locus_tag="NPJ86_25685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228056.1"
                     /GO_function="GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase YfcD"
                     /protein_id="WP_002913197.1"
                     /translation="MAEQNHLASTEWVDIVNENNEVIAQSSREQMRAQCLRHRATYIVV
                     HDGMGKILVQRRTETKDFHPGMLDATAGGVVQADEQLLESARREAEEELGIAGVPFADH
                     GQFYYEDKFCRVWGSLFSCVSHGPFALQEEEVSEVCWLTPEEITARCDEFTPDSLKALA
                     LWMTRNAGNEYDDAEESERE"
                     /name="yfcD"
     gene            complement(15166..17313)
                     /gene="pta"
                     /locus_tag="NPJ86_RS25690"
                     /old_locus_tag="NPJ86_25690"
     CDS             complement(15166..17313)
                     /gene="pta"
                     /locus_tag="NPJ86_RS25690"
                     /old_locus_tag="NPJ86_25690"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228055.1"
                     /GO_function="GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="WP_002913196.1"
                     /translation="MSRTIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRS
                     GGDAPDQTTTIVRASSSTTTAAEPLKMSHVESLLSSNQKDVLMEEIIANYHANTQDAEV
                     VLVEGLVPTRKHQFAQALNFEIAKTLNAEIVFVMSQGTDTPEQLNERIELTRNSFGGAK
                     NTSITGVIVNKLNAPVDDQGRTRPDLSEIFDDSSKAKIVKIDPAQLQKGSTLPVLGAVP
                     WSFDLIATRAIDMAHHLNATIINEGDINTRRVKSVTFCARSIPHMLEHFRPGSLLVTSA
                     DRPDVLVAACLAAMNGVEIGAILLTGGYEMDARISKLCERAFATGLPVFMVNTNTWQTS
                     LSLQSFNLEVPVDDHERIEKVQEYVANYINADWIESLTATSERSRRLSPPAFRYQLTEL
                     ARKAGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPDEINRVAAAQGVELGAGIEI
                     VDPEVVRESYVGRLVELRKNKGMTEAVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTT
                     ANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDPTAEQLAEIAIQSAES
                     AIAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADV
                     AKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGA
                     LVDDIVYTIALTAIQSAQQQK"
                     /name="pta"
     gene            complement(17514..18716)
                     /gene="ackA"
                     /locus_tag="NPJ86_RS25695"
                     /old_locus_tag="NPJ86_25695"
     CDS             complement(17514..18716)
                     /gene="ackA"
                     /locus_tag="NPJ86_RS25695"
                     /old_locus_tag="NPJ86_25695"
                     /EC_number="2.7.2.1"
                     /EC_number="2.7.2.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="WP_002913195.1"
                     /translation="MSSKLVLVLNCGSSSLKFAILDAVNGDEYLSGLAECFHLPEARIK
                     WKMDGSKQEAELGAGAAHSEALNFIVNTILAQKPELSAQLTAIGHRIVHGGEKYTSSVV
                     IDESVIQGIKDAASFAPLHNPAHLIGIAEALKSFPHLKDKNVAVFDTAFHQTMPEESYL
                     YALPYSLYKEHGVRRYGAHGTSHFYVTQEAAKILNKPVEELNIITCHLGNGGSVSAIRN
                     GKCVDTSMGLTPLEGLVMGTRSGDIDPAIIFHLHDTLGMSVDAINKMLTKESGLLGLTE
                     VTSDCRYVEDNYQEKADAKRAMDVYCHRLAKYIGSYTALMDGRLDAVIFTGGIGENAAM
                     VRELSLGKLGVLGFEVDHERNLAARFGKSGFINKEGTRPAVVIPTNEELVIAQDASRLT
                     A"
                     /name="ackA"
ORIGIN
        1 atgcgcccct tacgacaaaa ctggcatcga ccagttcagg cagaaaggtt atcaatgagc
       61 tggattgaac gaattaaaag caacatcact cccacccgca aggcgagcat tcctgagggt
      121 gtatggacca agtgcgacag ctgcggtcag gtactctacc gcgccgagct ggagcgcaac
      181 ctggaggttt gtcctaagtg cgatcaccat atgcgcatgt cggcgcgtaa tcgcctgcat
      241 agcctgttgg atgaaggttc tctggtagaa ctgggtagcg aacttgagcc aaaagatgtg
      301 ctgaagttcc gcgattcaaa aaaatacaaa gaccgcctgg cgtccgctca gaaagagacg
      361 ggcgagaaag acgcgctggt ggtgatgaaa ggtacgctct acgcgatgcc ggtggttgcc
      421 gccgcctttg aattctcctt tatgggggat cgatgggttc cgtcgtcggc gcacgctttg
      481 tacgcgcggt ggagcaggcg ctggaagata actgcccgct gatctgcttc tccgcctccg
      541 gtggcgcccg tatgcaggaa gcgctgatgt cgctgatgca gatggcgaaa acctccgcgg
      601 cgctggcgaa aatgcaggag cgcggactgc cgtacatctc cgtgctgacc gacccgacca
      661 tgggcggcgt atcggcgagc tttgcgatgc tgggagatct gaacattgcc gagccgaaag
      721 cgctgatcgg ctttgccggt cctcgcgtta tcgagcagac cgtacgcgag aagctgccgc
      781 cgggattcca gcgcagtgag tttctgattg aaaaaggggc gatcgatatg atcgttcgcc
      841 gtccgaaatg cgtctcaagc tggccagcat tctggcgaag ctgatgaacc tgccggcgcc
      901 gttgccgttt cggaagcgcc tcatgaaggc gtggtggtgc cgccggcacc ggatcaggaa
      961 cctgaggcct gataaagcag agggcagggc ctggcggcgc tgcccttttt tattcatacg
     1021 cgttaaccgt caattcttac gggcatcatg gaaaaagatc ctattcctca ggccacgtcg
     1081 cccctggcta cgtggctttc ttatctggaa catctgcaca gtaaaaccat cgaccttggg
     1141 ctggcgcgcg tcagcgaggt cgccgggcag atggatatcg ttaaaccggc gccgttcgtt
     1201 tttaccgttg cgggcaccaa tggcaaaggc accacctgcc gcacgctgga aaccatcctg
     1261 atggcggccg gttataaagt gggggtctac agctctccgc atctggtgcg ctacaccgaa
     1321 cgcgtgcgca ttcagggggc tgaactgccg gaggcggcgc atacggcttc gtttgctgaa
     1381 atcgaagcgg cgcggggtga catctcgctg acctattttg aatacggcac gctctcggcg
     1441 ctgtggctgt ttaagcaggc gcagctggat gtggtgatcc ttgaggtcgg gctcggcggg
     1501 cgtctcgacg ccaccaacat cgttgatgcc gacgtcgcgg tggtcaccag catcgccctc
     1561 gatcataccg actggctggg cccggatcgc gaaagtatcg gccgggaaaa agcgggcatc
     1621 tttcgcgccg gtaaaccggc ggtggtggga gccggatatg ccgctcacca tcgcggaagt
     1681 ggctagcgag aagggcgcgc tgctccagcg ccgcggcgtc gactggcgct atgaggtgga
     1741 aggcgaaaca tggtccttcc gcgatacggc aggggcgtta agccacctgc ctctgcctca
     1801 ggtgccgttg ccgaatgcgg cgacggccgt ggcggcgctg cgcgccagcg ggcttgccgt
     1861 ggatgacgct atcctgcgcg cagggatccg cgatgcgatg ctcccgggac gctttcagat
     1921 aatcagcgac gccccgcgag tgatcctcga tgtggcgcac aacccgcacg cggcggccta
     1981 tctcgccggg cgtctcaaaa cgttagcgaa aacgggacgc gtgctggcgg ttattggtat
     2041 gctgcatgat aaggacatcg ccggcacgtt ggccaatctg gctccggaag tcgatgcctg
     2101 gtactgcgcg ccgctggaag gcccgcgcgg cgcgacggca gagcagctgg tggaacattt
     2161 gcgctgcggt acagtctata gcagcgtggc gcaggcgtgg cgtgcggcca tggctgacgc
     2221 taaagtggaa gataccgtgc tggtgtgtgg ttcgtttcac accgtagcgc aggttatgga
     2281 agagatagac gcggggagaa tcggtggcga gtaagtttca gaaccgttta gtcgggacaa
     2341 tcgtgctggt ggcgctgggg gtgattatcc tgccagggct gctggacggg cagaaaaagc
     2401 attaccagga tgagtttgcc gcgatcccgc tggtaccgaa accgggcgat cgcgatgaac
     2461 cggatatgtt gccggcggca acccaggcgt tgccttcgca accgccggaa ggggcggcgg
     2521 aagaggtgcg ggcgggcgat gccgccgcgc catcgttaga tccatcgcgt attccggtga
     2581 acagcaacag cttcgatgac gttcaggagc cggtggtggc cgcgaaaccg cagcccaagc
     2641 cgcagccgaa accgcagccg caacagcagg ccgcgacgcc aacgccgccg ccggctaagc
     2701 cacagcagca acagccaccg cagcagcagg cggccctgcc ggcgccgacc ggcaaagcct
     2761 atgtggttca gctgggcgcg ttgaaaaacg ccgataaggt gaatgagatt gtcggtaaac
     2821 tgcgggcctc gggtttcaaa gtctatacgt cgccttcgac gccggtacag ggtaaaatta
     2881 cccgcatcct cgtcggcccg gatgcgtcaa aagacaagct gaaaggccag ctgggcgatc
     2941 tgcagcagat ctccgggctt agtggggtgg tgatgggctt caccccgaac tgattgtttt
     3001 ttccgccatg cggagagaac gtggcgggga gaaacgcccc gcaaaccctg tctcagccgc
     3061 cctgaagagg cgaaaggcag tctggcgttg aatgtttttt cagcgccatt tttatttctg
     3121 tagggcatgg aaatccctac gcaaacgttt tctttttctg ttagaatgcg ccccgaactg
     3181 gacgacaggg cgtaaatcgt gggacgtata tggtctggat tgattacgcc attatggcgg
     3241 tgctgggtct ttcttgcctg gtcagcctga tccgcggctt tgtccgcgaa gctttatcgt
     3301 tagtcacgtg gggttgcgcg ttttatgtcg ccagccatta ctacgctgac ctgtctgtct
     3361 ggtttacggg ctttgaggat gaacgggttc gaaatgggat tgctattgcg gcgctgttta
     3421 tcgtgacgct catcgttggc gctatcgtga actatgtgat aggccagctg gtggagaaga
     3481 ccggtttgtc aggaaccgac agggtattgg ggatctgctt cggcgcgcta cgtggggtgc
     3541 tgatcatcgc cgctatcctg ttcttcctgg atacctttac cgggatggcg aagagcgatg
     3601 actggcatca gtcgcagttt attccctatt ttacccccgt catcagatgg ttttttgaat
     3661 acctgcaaag ctcgtcaagt ttcttgccta aagtatagac tttgggtcgt tgctgaacga
     3721 ggaaaagacg tatgtgcggt attgtcggta tcgccggtgt tatgccggtt aaccagtcga
     3781 tttatgatgc gctaacggtg ctccagcacc gtggacagga tgccgctggc atcatcacca
     3841 ttgatgccaa caactgcttc cggttgcgta aggctaacgg gctggtaagc gacgtattcg
     3901 aggcccgcca catgcagcgt atgcagggca atatgggtat tggccacgtg cgttatccta
     3961 cggcgggcag ctccagcgcc tccgaggcgc agccgtttta cgttaactcg ccgtatggca
     4021 tcacattggc gcataacggc aacctgacca atgcgcacga gctgcgtaaa aagctgtttg
     4081 aagaaaaacg ccgccatatc aataccacct ctgattccga aatcctcctc aatattttcg
     4141 ccagtgagct ggataacttc cgtcactacc cgctggaagc ggacaacatc ttcgcggcga
     4201 ttgcggcgac caaccgcctg atccgcggcg cgtacgcgtg cgtggcgatg atcatcgggc
     4261 atggtatggt ggccttccgc gaccctaacg gcattcgtcc gctggtgctg ggtaaacgtg
     4321 acgttggcga cggtcgcacc gagtatatgg tggcctcgga gagcgtggcc cttgatacac
     4381 ttggttttga attcctgcgc gatgtggcgc cgggcgaagc ggtctatatt accgagaagg
     4441 gccagctcta tacccgtcag tgtgccgata atccggtcag caacccgtgc ctgttcgagt
     4501 acgtctattt tgcccgtccg gactcgttta ttgacaaaat ttccgtctac agcgcccgcg
     4561 tcaacatggg gactaagctg ggcgaaaaga ttgcccgcga gtgggaagat ctggatattg
     4621 acgtcgttat tccgatcccg gagacttcct gcgacatcgc gctggaaatc gcccgcattc
     4681 tcgacaaacc ttatcgtcag ggcttcgtga agaaccgcta cgtcggccgg acgtttatca
     4741 tgcccgtcag cagctgcgtc gtaaatctgt tcgccgtaag ctcaacgcca accgtgcgga
     4801 attccgcgat aagaacgtgc tgctggtcga tgattccatt gtacgcggca ccacctcgga
     4861 gcagatcatt gagatggcgc gtgaagcagg ggcgaaaaaa gtgtatctcg cctccgctgc
     4921 gccggaaatt cgtttcccga acgtgtacgg tatcgatatg ccgaccgcca acgaactgat
     4981 cgcccatggc cgcgaagtgg atgagatccg ccagatcatt ggcgccgacg gcctgatttt
     5041 ccaggatctc aacgatctga tcgacgcggt gcgcgcggag aacccggata ttcagcagtt
     5101 tgaatgctcg gtattcaacg gcgtatatgt gacccgggat gtcgaccagc agtacctcga
     5161 ctatcttgac tccctgcgta acgatgatgc caaagcggtc cagctgcaaa acgaagtcga
     5221 aaacctcgag atgcacaacg agggttaagc cgttcacgcg tcgcgggcct gccgtaccga
     5281 aaggacggcg ggcttttttt cgcccctcaa ctgtgcgtca atagttgcgc cagaggctat
     5341 aatccggcaa agtctgcggc acacgcgcaa ggggtaacag aacgtgaaac gactgattat
     5401 tggcatttcc ggcgccagcg gcgccattta cggcgtgcgg atgctgcagg tgctaagaga
     5461 tgtgccggat attgaaactc atctcatcct cagccaggcg gcgcgccaga cgttggccat
     5521 ggagaccgac tactccgtac gtgaggtgca ggcgctagcc gatgtggtgc atgacgcccg
     5581 cgatatcgcc gccagtatct cttccggttc gtttaaaacc gccgggatgg tgattttacc
     5641 ctgctcaatg aagacgctct cgggcattgt ccatagctat acggatggcc tgctgacccg
     5701 ggcggcggat gtcgtgctga aagagcgtcg tccgctggtg ctctgcgtgc gggaaacgcc
     5761 gttccatttg ggccatctgc gtctgctggt tcaggctgca gagctggggg cggtgataat
     5821 gccgccggta ccggcttttt accaccggcc acaaagcctg gacgatgtca tcaaccagac
     5881 cgtcaatcgg gtactcgatc aatttgatat tagtctggag cacgacttgt ttacccgctg
     5941 gcagggggcc tagtgtcgca ctatagtggt gcatgaaatg tacgcttgcg ctgcggtggt
     6001 gcaaatttgt tgccgcgatc aaatcctcga catttatttc gtctttttgc gctcaggcgc
     6061 tgcggtttcg ccagtaatgc tggtatcttc ccttttaaga caatcctgca actttatttt
     6121 aacaaattta accctgttcc cggcacgcac cgggaagatg gcacaaaaac tgcaggattg
     6181 atcggcaatc accataacaa gcaacgcacc acatcacgac acttaagggt actgtatgaa
     6241 gaagacgatt ctggctctct ctttactcgt gggaatgagc agcacggcca gcgtgtttgc
     6301 tgctctgccg cagagcattc gcattggcac tgacgcgacc tatgcgccat tttcgtcgaa
     6361 agacgcgaaa ggggactttg ttggctttga tatcgattta ggcaatgagt tgtgctcccg
     6421 aattaaggtg aaatgtacct gggtcggcag tgattttgac tccctgatcc cctccctgaa
     6481 ggcgaagaag attgacgcca tcatctcttc cctctctatt accgagaagc gccagcaaga
     6541 gatcgccttc tctgacaagc tatatgccgc tgactcgcgt ctgatcgccg ccaaagggtc
     6601 gccgatccag ccgacgctgg aggcgctgaa aggcaagcac gtcggcgtgc tgcagggttc
     6661 tactcaggaa gcctatgcta acgaccgctg gcgcagccag ggcgttgacg tggtggctta
     6721 ccagaaccag gatctgatct attcagacct cgcagctggc cgtctggatg cggcgctgca
     6781 ggatgaagtc gccgccagcg aaggcttcct gaaacagcct gccgggaaag atttcgcctt
     6841 cgccggcccg tccgttaaag acaaaaagta ctttggcgac ggcaccggta tcggcctgcg
     6901 taaggacgac gctgagctga aagccgcgtt tgataaagcg ctgggcgaga tgcgtaaaga
     6961 cggcacctac gacaaaatgg cgaagaaata cttcgatttt aacgtgtacg gcgactaaga
     7021 ctgctgcagg cccgcacaat ggggtgggcc tgccgccagg ttcgtatcca tgccccaaaa
     7081 gggtgcatct aaacgcgctg tggatcattt cagtgcaaaa gcagccagtt ttttggctaa
     7141 aaaatgcata gttaagcgtt tctgatgcaa aaaatcggcc tttctggtgc ataaatcttt
     7201 gcccttaagg ggcgaataat ggcacgataa ctggcgtaaa tagttctaat aaacccgtta
     7261 gaatgacagt ctgtcgagga tagttatgaa aaaactggcg ttgtctctct ctttagcgct
     7321 ggccctttcc agcgtttcca cggtctttgc cgccatcccg caaaaaattc gtatcggtac
     7381 cgatccgact tatgctccct tcgaatcgaa gaatgcgcag ggagaattgg tcggttttga
     7441 tatcgatctg gcaaaagagc tgtgtaagcg tattaatacg caatgtacct ttgttgaaaa
     7501 cccgctggat gcgctgatcc cctccttaaa agcgaagaaa atcgacgcga ttatgtcttc
     7561 gctgtcgatt actgaaaagc gtcagcagga aattgccttc actgacaagc tgtatgcggc
     7621 agattcgcgt ctggtggtga aaaagggcag cccggtaacg ccggatctcg ccaccctcaa
     7681 gggtaagcgc gtgggcgtgc tgcaggggac gactcaggaa acctatggca atgagcactg
     7741 ggcgccgaaa ggtatcgaaa ttgtctccta tcaggggcag gacaatatct attccgacct
     7801 gaccgccggc cggatcgacg ccgcgttcca ggatgaggtc gcggccagcg aagggttcct
     7861 gaaacagcct attggtaaag attaccagtt tggtggcccg tcaatcaaag acgagaaact
     7921 atttggtgtt ggcaccggta tggggctgcg taaggaagac aacgaactgc gtgaagcgct
     7981 gaataaggcg tttgcagaga tgcgtaagga cggcacctac gacaagctgg cgaaaaaata
     8041 tttcgatttt aacgtatacg gcgaataatt ctcacgcctc gccattgcgt gcgtttcgcg
     8101 cgcaatggtg aatgacagac agggtaggca gcatgctgta tgggttttca caggttattt
     8161 tgcagggtgc gctcgtcacc ctggagcttg cgctcagctc ggtcgttctc gccgtcctga
     8221 ttgggctggc gggcgctggc gcaaagttat cgagcaaccg tccactggcg ctggtgtttg
     8281 aaggctatac cactctgatc cgcggcgtgc ccgatctggt gctgatgctg ttgattttct
     8341 acggcctgca gattgcgcta aacagcgtta ccgatgcgct gggcatggcc cagtttgata
     8401 tcgatccgat gatcgccggg attattaccc tcggctttat ctatggcgcc tattttacgg
     8461 aaaccttccg cggcgcctac cttgcggtgc cgaaggggca tatcgaagcg gccaccgcct
     8521 ttggctttag cggcgggcag acgttccggc gtattctctt cccggcgatg atgcgctacg
     8581 cgctgccggg gataggcaac aactggcagg ttatcctcaa ggcgacggcg ctggtctcgt
     8641 tgctggggct ggaggatgtg gtcaaagcca cgcagctggc cgggaaaagc acctggcagc
     8701 cgttctactt cgccatcgtc tgcggcctga tttatctggt gtttaccacc gtttctaatg
     8761 gcgtactgct gctgctcgaa cgccgctata ccgttggcgt gaagagggct gacctgtgat
     8821 tgaaattatt caggagtact ggaaatcact actgtggacc gacggctatc gctttaccgg
     8881 cgtggcgatt accttatggt tgctgatctc ttcagtggta atggggggca tcctggcggt
     8941 gtttctggcc atcggccgcg tctcgagcaa taagtttatc cagttcccca tctggctgtt
     9001 cacttacata tttcgcggca cgccgctgta tgtgcaactg ctggtttttt actccggcat
     9061 gtataccctg gaaatcgtca aaggcacgga gctgttgaac gcttttttcc gcagcgggct
     9121 aaactgcacg gtactggcgt taaccctgaa tacttgcgcc tataccactg aaattttcgc
     9181 cggcgcgatc cgctcagtac ccgccggaga aattgaagcg gcgcgggcct acggcttctc
     9241 gtcagtcaaa ctgtatcgct gcattattct gccttccgcg ctgcggattg cactgccggc
     9301 ctacagtaac gaagtgatcc tcatgctgca ctctaccgcg ctggcgttta ccgctacggt
     9361 accggatctg ctgaaaatcg cccgcgatat caactcggcc acctatcagc cgttcaccgc
     9421 gtttggcatc gccgcggtgc tctatttaat tatctcgtat gtgctgatta gcttgttccg
     9481 taaagcggaa aagcgctggt tgcagcatat caaaccttct tcgacgcatt gagaacgcca
     9541 tgtccgacaa taaattaaac gttatcgatc tgcataaacg ctatggggaa cacgaggtgc
     9601 tgaagggcgt ctcgctgcag gcgaaagccg gggacgttat cagcatcatc ggttcatcgg
     9661 gttccggaaa aagtaccttt ttgcgctgta ttaacttcct tgaaaaaccg agcgaaggca
     9721 cgatcgtcgt cagcggccaa aatattggtc tggtacggga taaagacggc cagctgaagg
     9781 tggccgacaa gaaccagttg cgcctgctgc gcacccggtt gaccatggtg tttcagcatt
     9841 tcaatctgtg gagccatatg acggtgctgg agaacgtcat ggaagcgccg attcaggtgc
     9901 tgggcttaag caaacaggaa gcgcgcgaac gggcggtaaa atatctggcc aaggtcggga
     9961 tagacgaacg tcagcaggcg aagtatccgg tgcatctttc cggtggccag cagcagcgtg
    10021 tctctattgc ccgcgcgctg gcgatggaac cggaagtgct gctgtttgat gagccgacct
    10081 ccgcgctgga tccggaactg gtgggcgaag tgttacgcat tatgcagcag ctggcggaag
    10141 agggaaaaac catggtggtg gtgacccatg aaatgggctt tgcccgccac gtctcttcac
    10201 atgtcatttt tctgcatcag ggtaaaattg aagaagaagg gcatccggat gcgctgtttg
    10261 gcgcgccgaa aagcccgcgc ctgcagcagt ttctgaaagg ttcgctgaaa taatcggctc
    10321 atccggcgtc tgcggacgcc ggatgagctt cccgctccag ccgatagatc cagtcatcgt
    10381 aatcgacgcc gttcagatga taggctttct ccagcacctg ggtgcgcaca aagccttgct
    10441 tctccagcag gcgcgatgag ccacggtttt cacccagcac ccaggcattg atggcctgca
    10501 cccccagggt ggtgaaacca tactcgcaga ccgcccgcag cgcttcgctg gcatagcctt
    10561 ttccctgagc ctgaggcagc agcgcgtagc cgacgtcagc ttcgtgcgga tttttcggac
    10621 tgatgcggag cccaatatcg cccagcgcct cgccgaattt atcgcgcaat acaaacaccc
    10681 cgggatcggc acagcgactg acgaagacgc tgcgcagcgc ctcctcgctt aacacctccc
    10741 ccataaaacg catcacctgc ggatcctggc gcaggcgcag aaaaaagggc cagtcatcgg
    10801 taacaaagcg ggtaagcgaa aggcgtggtg tggtgatggt cgtcataaag cagtcaatac
    10861 gcagaaagaa aagcctacct tagcactttg ctttgccagg taacaccggc gaaccggccg
    10921 gctggcggtg aattcaggcg attaagggcg ctggttgtcc tgaatatggc gatgctgcag
    10981 cgccagggtg aggccatcca ggcgtggagc acgagccagc agaatggaat cagaggagcc
    11041 aatgctcccc tgtgtcagcc attaactcag cacatccttt agcgtttcgt ccagatcgta
    11101 ccagcggaag gcaaagccgg cggcctccag acgctttggc agcgcgcgct ggccgccaag
    11161 caccaggacg gcggattccc ccatcaacag gcggatagcg gcggcgggaa cgcggaaaat
    11221 cgccggtcga tggagcgcat gacccagcgc atgggcgaac tgctcgttat gcaccgggta
    11281 gggagaaacc atattgaacg gaccgcgcag atcgttatcc agcagccaca gaatgccgtt
    11341 aaccatatcg tcgatatgga tccaggccag gtactgtctg ccgttgccga taggcccgcc
    11401 gaggccgagc ttaaaggcgg gtgtcatttt gccgagaata ccgccccgcg gagccagtac
    11461 cacgccggtg cgcagcaggc agacgcgggt gcgctcgctt tgcgcttcgc aggcaatttg
    11521 ttcccagcgg gcgcacagct tatgggtaaa ctcattgtgc ggtggctctt cttcggtcac
    11581 caccacctcg ccgaggtcgc catagtagcc gatggcagac ccgctgatca gcacggaggg
    11641 aggggtgtcg ctggcgtgga tcaggcccac cagccgctgc gtgagatccc agcggctatg
    11701 gcacaagcgt tgtttctgct cggccgtcca gcgtttatca gcgatgggtt cacccgccag
    11761 attgatgacg gcatcaatat cattgaggtg gtgatggccc tcgaaatcgc gccacagggt
    11821 gacgcgcgga tcgagacggg cgcgggcggt atccggatgt cgcgtggaga ccgtgacgct
    11881 atgcccgagc tccagcaatc tgggtatcag atgtcggcca atcaggccgg taccaccagt
    11941 aagcaggatc ttcataccac ctccctgaca tggttagcga cgccagctca tggtcatgga
    12001 caccgagtcg gcatagcgca gcgcatgaag tttatcaatc tccacttcag catatgtgac
    12061 ccagtgatgt tcgcatgcga tattcagcac atcctgagtt aatttttcca gcagcgaaaa
    12121 acggccattc tcaagatggc tgattatgcg cttggtaatg gtgcgatagt tcagcgcatc
    12181 attgatgtcc tcgctgtcgc gcgctttatc ggcagggtag tgaatggcta cattcactac
    12241 cacgtcctgg cggttggcga tctcttcctc tttaatacca ataaaagtcc gcaggcgcag
    12301 gttcttaata cgaataatgg cgtctggttg agacattgca ggcttcctcc gtggtgtaag
    12361 tcctgcaatc atacaacaaa gcgcgacggg cgagcagggg gttaataaag ctgaattttt
    12421 aacatcgctt ccgccgttgc cggccgctgc ttaatgcgct cataccagtt gtgcaccgcc
    12481 ggatagttcg ccagatcgat acgctgtcgg acatggcagt tcacccaggg ccaggcggcg
    12541 atgtcggcga tactgtagtg gtcgccgcca agccacgggc tgcatcccag acgctgattt
    12601 agcaccccat acagtcgttg ggtttccacc tgaaaacgtt caatagcgta gggcacggtt
    12661 tgcggcgcgg agtgggaaaa atgttgattt tgccccagca tcggccccag cccgccgacc
    12721 tgccagaaca gccactgcag cgtgacgtag cgttcccgca gctcgccgct cagcagctta
    12781 ccgctttttt ccgccagata gagcaggatg gcgccggact cgaaaacgct caacggcgcc
    12841 ccgccgtcag caggcatgtg gtcgacgata gccggaactt tattattcgg cgaaatcgcc
    12901 agaaactgcg gatgaaattg ttcccctttg ccgatatcga cccgaattag ccgataggct
    12961 agctccgcct cttcgaggaa cagggtgatt ttgtggccgt ttggggtggg tgcatagtaa
    13021 agatcgatca taatatttcc cgccgtcgtg ggtcgcaaac tgttcgagta taggtgaagc
    13081 tgcgccaccc gggagaaatt ccgcaagcga cccggcagcc aggcgacgag tcgtccgcgc
    13141 tcgagcagtg acatcgcctg taagacaggc tatgttggct tattgtcctg tctaccaccc
    13201 ttgaggaagc tatgagccag cctgtcatta ccctgtggtc cgatgccgat tttttctcac
    13261 cgtacgtgat gtctgtctat gtcgctctgc aggaaaaaag cctgcctttt acccttaaaa
    13321 ccgtcgacct gaaccgcggc gaacatctgc aggcgggctg gacaggctat gccgccaccc
    13381 gtcgcgtacc gctgctggag gttgatgatt tcgcgctaag tgagtcttcg gcgattaccg
    13441 agtatctgga tgagcgtttc gcgccgccgg agtgggagcg catctacccg catgatctgc
    13501 aaaaacgagc ccgcgcccgg cagatccagg cctggctgcg cagcgatctg atgccaattc
    13561 gtgaagagcg atccaccgcc gtggtgtttg gcggggcgaa aatgccggac ctcagcgagg
    13621 ccggcaggca atctgcggaa aagctgtttg ccaccgccac catgctactg gcccacggcg
    13681 ggcaaaattt atttggcgaa tggtctattg ccgacgcaga cctggcgctg atgctcaatc
    13741 gcctggttct caatggcgat aaggtaccgg aggcgctggc tgattatgcg tctttccagt
    13801 ggcagcgggc ctcaatccag cgttacgtgg cgctttccgc caaacgctga ggctgataac
    13861 ccgccgcgct tccgctatca tagaggcatc gtaaccagtg gagatggaac ctatgaagct
    13921 gatgtttgcc tccgatattc atggttcgct gcccgccacg gaacgcgtgc ttgaacggtt
    13981 cgcgcaaagc ggcgccaggt ggctgatcat actcggcgat gtgctcaatc acggtccgcg
    14041 taacgcgctg cctgaggggt atgcgccggg tgaggtggcg gagcggttga acagcgtggc
    14101 ggaacgcatt gttgccgttc gcggcaactg cgacagcgaa gtggatcaga tgctgcttcg
    14161 ttttccaatc accgcgccct ggcagcaggt gcttagcgaa cgctatcgcc tgtttctgac
    14221 ccacgggcat ctctatagtc cggataatct gccgccgctg gccgctggcg atgtcctggc
    14281 atatggccat actcatatac cggtcgcgga aaaacgcggc gcaatttacc tctttaatcc
    14341 cggctcagtg agtatcccga aagggggata ttccgccagc tatgggctgc tggatcaggg
    14401 gcggctgcag gttttagcac tcaatgataa tcaggttatt gcagaggttg caatttaccc
    14461 gtaatttagc cctcaatcat aaagacgcgc cgcgagagcg catttaaagt aaggtttcct
    14521 gatggcggaa cagaatcatt tggcaagcac agaatgggtc gatattgtta atgaaaacaa
    14581 tgaggtgata gcacagtcca gccgcgagca aatgcgcgcg cagtgcctgc gccaccgggc
    14641 gacctatatc gtcgttcatg acggaatggg gaaaattctg gtgcagcgac gcaccgagac
    14701 aaaagacttt catccgggca tgctggatgc caccgctggc ggcgtcgtgc aggctgatga
    14761 gcagctgctg gaatcggccc gtcgcgaggc ggaagaggag ttaggcatcg ccggggtgcc
    14821 gtttgccgat cacggccagt tttattacga agacaaattc tgccgcgtct ggggaagcct
    14881 gttcagctgc gtctcccacg ggccgttcgc cctgcaggaa gaagaggtca gcgaggtgtg
    14941 ctggttaacg ccggaagaga tcaccgcccg ctgcgatgag ttcacgccgg actccctgaa
    15001 agcgctggcg ctgtggatga cccgcaacgc cggtaatgag tatgatgatg cggaagagag
    15061 cgagcgcgaa taaagatcgc aaacgcgcgg cagcaatcgt cgctcgcctc ctgacgacaa
    15121 aaaggcagcc attcggctgc cttttgcttt gaccacagcg gcagattact tctgctgctg
    15181 agccgattgg atcgcggtca gtgcgatggt atagacgata tcgtctacca gcgcgccacg
    15241 ggacaggtcg ttgaccggct tgcgcatacc ctgcagcatc ggcccgatgg agatcaggtc
    15301 ggcagagcgc tgtaccgctt tgtacgtggt gttaccggtg ttcagatccg ggaagatgaa
    15361 cacggtcgcg cggccagcta ccggtgagtt cggcgctttg gacttcgcta cgtcagccat
    15421 caccgcggcg tcatactgca gcgggccgtc gatcatcagg tcaggacgtt tttcctgcgc
    15481 cagacgggtc gcttcgcgga ctttctcgac atcgctaccc gcgccggagg taccggtgga
    15541 gtaggagagc atcgctacgc gcggttcgat gccgaaggca atcgcggatt cagcggactg
    15601 aatagcgatt tccgccagct gctcggctgt cgggtccggg ttgatcgcgc agtcgccgta
    15661 aacgtaaacc tgttccggca gcagcatgaa gaacacggag gagaccagcg agctgcccgg
    15721 cgcggttttg atcagctgca gcggcggacg aatggtgttg gcagtggtgt gaaccgcgcc
    15781 ggataccaga ccgtcgactt cgtcctgttc cagcatcagg gtgccgagaa ccacgttgtc
    15841 ttccagctgc tcacgcgcga ccgcttcggt catgcctttg ttcttacgca gttcgaccag
    15901 gcgacccaca tagctttcgc gaaccacttc cggatcgacg atttcaatgc cggcgccaag
    15961 ctccacgccc tgggccgcgg ctacgcggtt gatctcatcc gggttaccca gcaggacaca
    16021 ggtggcgatc ccgcgttcgg cgcaaatcgc cgccgctttc acggtacgcg gttcgtcgcc
    16081 ttccggcaga acgacacgtt tgccggcttt gcgcgccagc tcggtcagct ggtagcggaa
    16141 ggctggcgga gagagacggc ggctgcgctc ggaggtcgcg gtcagcgatt cgatccagtc
    16201 ggcgttgata tagttggcca cgtattcctg aactttctcg atacgctcgt gatcgtcaac
    16261 cggtacttcg aggttaaagc tctgcaggct cagggaggtc tgccaggtgt tggtgttgac
    16321 catgaatacc ggcaggccgg tcgcgaaagc gcgttcacac agcttgctga tgcgcgcgtc
    16381 catttcatag ccgccggtca gcagaatggc gccgatttcc acgccgttca ttgccgccag
    16441 gcaggccgca accagcacgt caggacggtc tgcggaggta accagcagag aaccagggcg
    16501 gaagtgttcc agcatgtgcg ggatgctgcg tgcgcagaaa gtcacggatt tcacgcggcg
    16561 ggtattgata tcgccttcgt tgatgatggt cgcattcaga tggtgagcca tgtcgatcgc
    16621 gcgggtcgcg atcagatcga agctccatgg cactgcgccc agcaccggca gcgtgctgcc
    16681 tttctgcagc tgagccgggt caatcttcac gatttttgct ttcgacgagt cgtcgaaaat
    16741 ttccgacagg tcaggacggg tacggccctg atcgtcgaca ggggcattca gtttgttgac
    16801 gataacgccg gtgatgctgg tatttttggc gccgccaaag ctgttacggg tcagttcgat
    16861 acgctcgttc agctgttctg gcgtgtcggt gccctgagac atcacgaaga cgatttcagc
    16921 gttcagcgtt ttggcgattt caaagttcag cgcctgggcg aactgatgct tacgggtcgg
    16981 taccaggcct tccaccagca ccacttccgc gtcctgagta ttcgcgtggt agttggcaat
    17041 gatctcttcc atcagcacat ctttctgatt gctggagagc agagactcaa catggctcat
    17101 cttcagcggt tcagcggcgg tggtggtgga ggagctggcg cgaacgatgg tggtggtctg
    17161 gtctggggca tcgccaccgg aacgcggctg ggcgataggt ttaaagacgc tcagacgaac
    17221 gcctttgcgt tccatagcgc ggatcacacc gaggctgacg ctggtcagac ctacgctggt
    17281 accggtagga attaacatga tagtacggga cacggtatat cctctttcgt taccgccagt
    17341 atcaggcggg atacaaaaca gcaccgccag ctatccgtca tatttcaagt tgcacgtgcg
    17401 ttggctctac ttgctcaccc cggtggcgta cgcgctgtac gcggccgggg ttttgctgtg
    17461 tcgccgcctt cctgcagctc gaattattgc gggtcagggc tggcgatgtg gaattatgcg
    17521 gtcagacggc tggcgtcttg cgcgatgacc agctcttcgt tggtcgggat aaccacggca
    17581 ggacgggtgc cttctttgtt gatgaagcca gacttgccga agcgggcagc aaggttacgc
    17641 tcatggtcaa cttcaaagcc cagtacgccc agtttgccca gcgacagctc acgcaccatc
    17701 gcggcgtttt caccgatacc accggtgaaa ataacggcgt caagacggcc gtccatcagc
    17761 gcggtgtagg aaccgatgta tttcgccagg cggtggcagt aaacgtccat cgcgcgttta
    17821 gcgtcggctt tttcctgata gttgtcttcc acgtagcggc agtcgctggt gacttcggtc
    17881 agacccagca ggccggactc tttggtcagc attttgttga tcgcgtcaac gctcatgccc
    17941 agggtgtcgt gcagatggaa gatgatggcc ggatcgatgt caccggagcg ggtacccatc
    18001 accagacctt ccagcggggt cagacccatg gaggtgtcaa cgcatttacc gttacggata
    18061 gcggaaacag aaccaccgtt gccgaggtgg caggtgatga tgttcagctc ttccaccggc
    18121 ttgttgagga tcttagcggc ttcctgagtc acgtagaagt ggctggtgcc gtgcgcgccg
    18181 taacgacgaa cgccgtgctc tttgtacagg ctgtacggca gggcgtagag ataggattct
    18241 tccggcatgg tctgatggaa cgccgtatcg aatacagcca cgtttttgtc tttcaggtgc
    18301 gggaaggatt tcagcgcttc agcgatgccg atcaggtgtg ccgggttgtg cagcggtgcg
    18361 aaagacgcgg cgtctttaat accctgaatt acggactcgt cgatcaccac ggagctggtg
    18421 tatttttcac cgccgtgtac gatacggtgg ccgattgcgg tcagctgagc agacagttct
    18481 ggtttttgtg ccagaatagt gttaacgata aagttcagcg cttcactgtg cgcggcgccc
    18541 gcgcctaact cggcttcttg tttgctgccg tccattttcc atttgatacg ggcttccggc
    18601 aggtggaagc attccgctaa accggacaga tattcgtcgc cgttcacggc gtcaaggata
    18661 gcaaatttca gagaggagct accgcagttc agaaccagta ctaacttact cgacatggaa
    18721 gtaccttttt atgatacgtg gctaaaaaaa cgtcagtgtg tcattagcgt agcgcaggat
    18781 gacctcgaca tttatgatta acatcatgcc ttgttctgtt ttcgggcacg atgagagaag
    18841 tacatttgat tttatgccat tttgcataat tttcagccaa tggcagaata tgcgataatt
    18901 tgactagcct ggcaaagagt ctaaccgccc tttcaggcgg gcacaggata ctgattgcgg
    18961 catcctttgc caaaatcttt tgaacgatgt catgcatagt tggtgttttg cacgaa
//
