LOCUS       NZ_CP100692            11080 bp    DNA     circular CON 23-JUL-2023
DEFINITION  Salmonella enterica subsp. enterica serovar Typhimurium strain
            R17.3867 plasmid pR17.3867_11k, complete sequence.
ACCESSION   NZ_CP100692
VERSION     NZ_CP100692.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN27531299
            Assembly: GCF_024266305.1
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica subsp. enterica serovar Typhimurium (Salmonella
            typhimurium)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhimurium
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11080)
  AUTHORS   Chiou,C.S., Chen,B.H., Wang,Y.W. and Teng,R.H.
  TITLE     28 Salmonella enterica strains that have azithromycin resistance
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11080)
  AUTHORS   Chiou,C.S., Chen,B.H., Wang,Y.W. and Teng,R.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUL-2022) Center for Diagnostics and Vaccine
            Development, Centers for Disease Control, Taiwan, No.20, Wenxin S.
            3rd Rd., Nantun Dist., Taichung City 408, Taiwan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: flye v. 2.9; trycycler v. 0.5.3; medaka v. 1.6.0;
            homopolish v. 0.3.3; polca v. 4.0.5; polypolish v. 0.5.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 649x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 07/23/2023 01:52:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,884
            CDSs (total)                      :: 4,761
            Genes (coding)                    :: 4,618
            CDSs (with protein)               :: 4,618
            Genes (RNA)                       :: 123
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 15
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 38 of 143
            Pseudo Genes (incomplete)         :: 109 of 143
            Pseudo Genes (internal stop)      :: 27 of 143
            Pseudo Genes (multiple problems)  :: 28 of 143
            Pseudo Genes (short protein)      :: 1 of 143
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP100692.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..11080
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhimurium"
                     /mol_type="genomic DNA"
                     /strain="R17.3867"
                     /serovar="Typhimurium"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90371"
                     /plasmid="pR17.3867_11k"
                     /geo_loc_name="Taiwan: Taichung"
                     /collection_date="2017"
                     /collected_by="Centers for Disease Control, Taiwan"
                     /subtype="ST36"
     gene            complement(join(10712..11080,1..483))
                     /gene="repC"
                     /locus_tag="NL690_RS24325"
                     /old_locus_tag="NL690_24325"
     CDS             complement(join(10712..11080,1..483))
                     /gene="repC"
                     /locus_tag="NL690_RS24325"
                     /old_locus_tag="NL690_24325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein C, IncQ-type"
                     /protein_id="WP_000240536.1"
                     /translation="MVKPKNKHSLSHVRHDPAHCLAPGLFRALKRGERKRSKLDVTYDY
                     GDGKRIEFSGPEPLGADDLRILQGLVAMAGPNGLVLGPEPKTEGGRQLRLFLEPKWEAV
                     TADAMVVKGSYRALAKEIGAEVDSGGALKHIQDCIERLWKVSIIAQNGRKRQGFRLLSE
                     YASDEADGRLYVALNPLIAQAVMGGGQHVRISMDEVRALDSETARLLHQRLCGWIDPGK
                     TGKASIDTLCGYVWPSEASGSTMRKRRQRVREALPELVALGWTVTEFAAGKYDITRPKA
                     AG"
                     /name="repC"
     gene            complement(470..1309)
                     /locus_tag="NL690_RS24330"
                     /old_locus_tag="NL690_24330"
     CDS             complement(470..1309)
                     /locus_tag="NL690_RS24330"
                     /old_locus_tag="NL690_24330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001517559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase RepA family protein"
                     /protein_id="WP_000190708.1"
                     /translation="MATHKPINILEAFAAAPPPLDYVLPNMVAGTVGALVSPGGAGKSM
                     LALQLAAQIAGGPDLLEVGELPTGPVIYLPAEDPPTAIHHRLHALGAHLSAEERQAVAD
                     GLLIQPLIGSLPNIMAPEWFDGLKRAAEGRRLMVLDTLRRFHIEEENASGPMAQVIGRM
                     EAIAADTGCSIVFLHHASKGAAMMGAGDQQQASRGSSVLVDNIRWQSYLSSMTSAEAEE
                     WGVDDDQRRFFVRFGVSKANYGAPFADRWFRRHDGGVLKPAVLERQRKSKGVPRGEA"
                     /name="helicase RepA family protein"
     gene            complement(1339..1545)
                     /gene="urfF"
                     /locus_tag="NL690_RS24335"
                     /old_locus_tag="NL690_24335"
     CDS             complement(1339..1545)
                     /gene="urfF"
                     /locus_tag="NL690_RS24335"
                     /old_locus_tag="NL690_24335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007857788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid repression protein F"
                     /protein_id="WP_007857788.1"
                     /translation="MKDQKDKQTGDLLASPDAVRQARYAERMKAKGMRQRKFWLTDDEY
                     EALRECLEELRAAQGGGSDPASA"
                     /name="urfF"
     gene            complement(1547..1759)
                     /locus_tag="NL690_RS24340"
                     /old_locus_tag="NL690_24340"
     CDS             complement(1547..1759)
                     /locus_tag="NL690_RS24340"
                     /old_locus_tag="NL690_24340"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000455501.1"
                     /translation="MEYEKSASGSVYLIKSDKGYWLPGGFGYTSNKAEAGRFSVADMAS
                     LNLDGCTLSLFREDKPFGPGKFLGD"
                     /name="hypothetical protein"
     gene            complement(1820..2689)
                     /locus_tag="NL690_RS24345"
                     /old_locus_tag="NL690_24345"
     CDS             complement(1820..2689)
                     /locus_tag="NL690_RS24345"
                     /old_locus_tag="NL690_24345"
                     /inference="COORDINATES: protein motif:HMM:NF028103.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-primase RepB domain-containing protein"
                     /protein_id="WP_229382459.1"
                     /translation="MNREWSAAEVLQNTPWLKRMNAQGNDVYIRPAEQERHGLVLVDDL
                     SEFDLDDMKAEGREPALVVETSPKNYQAWVKVADAAGGELRGQIARTLASEYDADPASA
                     DSRHYGRLAGFTNRKDKHTTRAGYQPWVLLRESKGKTATAGPALVQQAGQQIEQAQRQQ
                     EKARRLASLELPERQLSRHRRTALDEYRSEMAGLVKRFGDDLSKCDFIAAQKLASRGRS
                     AEEIGKAMAEASPALAERKPGHEADYIERTVSKVMGLPSVQLARAELARAPAPRQRGMD
                     RGGPDFSM"
                     /name="DNA-primase RepB domain-containing protein"
     gene            complement(2788..3201)
                     /locus_tag="NL690_RS24350"
                     /old_locus_tag="NL690_24350"
     CDS             complement(2788..3201)
                     /locus_tag="NL690_RS24350"
                     /old_locus_tag="NL690_24350"
                     /inference="COORDINATES: protein motif:HMM:NF036929.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncQ-type mobilization protein MobB"
                     /protein_id="WP_010890157.1"
                     /translation="MNAIDRVKKSRGINELAEQIEPLAQSMATLADEARQVMSQTQQAS
                     EAQAAEWLKAQRQTGAAWVELAKELREVAAEVSSAAQSARSASRGWHWKLWLTVMLASM
                     MPTVVLLIASLLLLDLTPLTTEDGSIWLRLVAR"
                     /name="IncQ-type mobilization protein MobB"
     gene            complement(<3359..3811)
                     /locus_tag="NL690_RS24355"
                     /old_locus_tag="NL690_24355"
                     /pseudo=""
     CDS             complement(<3359..3811)
                     /locus_tag="NL690_RS24355"
                     /old_locus_tag="NL690_24355"
                     /inference="COORDINATES: protein motif:HMM:NF015354.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /name="MobA/MobL family protein"
     gene            4148..4432
                     /locus_tag="NL690_RS24360"
                     /old_locus_tag="NL690_24360"
     CDS             4148..4432
                     /locus_tag="NL690_RS24360"
                     /old_locus_tag="NL690_24360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mobilization protein C"
                     /protein_id="WP_000238497.1"
                     /translation="MVKGSNKAADRLAKLEEQRARINAEIQRVRAREQQQERKNETRRK
                     VLVGAMILAKVNSSEWPEDRLMAAMDAYLERDHDRALFGLPPRQKDEPG"
                     /name="mobilization protein C"
     gene            4891..5331
                     /locus_tag="NL690_RS24365"
                     /old_locus_tag="NL690_24365"
     CDS             4891..5331
                     /locus_tag="NL690_RS24365"
                     /old_locus_tag="NL690_24365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008166363.1"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_025732385.1"
                     /translation="MSSNGRHFGEIRLSALKKAPEMFGSVYEHEEKKPMEAFAERLRDA
                     VAFGAYIDGEIIGLSVFKQEDGPKDAHKAHLSGVFVEPEQRGRGVAGMLLRAVIDYGRE
                     HVEQIMLTVAEGNEAAINLYQRSARCPAPLQSPRRSAGRQSK"
                     /name="GNAT family N-acetyltransferase"
     gene            complement(5262..6461)
                     /gene="tet(A)"
                     /locus_tag="NL690_RS24370"
                     /old_locus_tag="NL690_24370"
     ARG             complement(5266..6461)
                     /name="tet(A)"
                     /gene="tet(A)"
                     /gene_name="tetracycline efflux MFS transporter Tet(A)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="99.75"
                     /coverage="100.0"
     gene            6567..7217
                     /gene="tetR(A)"
                     /locus_tag="NL690_RS24375"
                     /old_locus_tag="NL690_24375"
     CDS             6567..7217
                     /gene="tetR(A)"
                     /locus_tag="NL690_RS24375"
                     /old_locus_tag="NL690_24375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional repressor
                     TetR(A)"
                     /protein_id="WP_012850383.1"
                     /translation="MTKLQPNTVIRAALDLLNEVGVDGLTTRKLAERLGVQQPALYWHF
                     RNKRALLDALAEAMLAENHTHSVPRADDDWRSFLIGNARSFRQALLAYRDGARIHSGTR
                     PGAPQMETADAQLRFLCEAGFSAGDAVNALMTISYFTVGAVLEEQAGDSDAGERGGTVE
                     QAPLSPLLRAAIDAFDEAGPDAAFEQGLAVIVDGLAKRRLVVRNVEGPRKGDD"
                     /name="tetR(A)"
     gene            complement(7259..7501)
                     /locus_tag="NL690_RS24380"
                     /old_locus_tag="NL690_24380"
     CDS             complement(7259..7501)
                     /locus_tag="NL690_RS24380"
                     /old_locus_tag="NL690_24380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_000844627.1"
                     /translation="MKTAALDLARERQAHEAGARTRATAHERTPQQERQKAAREAERGR
                     EAWTLGQGMKKPVAGCYGRLTRWKGGGDVVYMALL"
                     /name="transposase"
     gene            complement(7888..8724)
                     /locus_tag="NL690_RS24385"
                     /old_locus_tag="NL690_24385"
     CDS             complement(7888..8724)
                     /locus_tag="NL690_RS24385"
                     /old_locus_tag="NL690_24385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /protein_id="WP_000480968.1"
                     /translation="MFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLKP
                     IEDIADELRGADYLVWRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATEIA
                     AELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMMSNA
                     SELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDPRRIA
                     QMADAFSRALDVDPRRLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQTSY"
                     /name="aminoglycoside O-phosphotransferase APH(6)-Id"
     ARG             complement(8725..9143)
                     /name="APH(3'')-Ib"
                     /gene="APH(3'')-Ib"
                     /gene_name="APH(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="52.06"
     ARG             complement(8728..9527)
                     /name="aph(3'')-Ib"
                     /gene="aph(3'')-Ib"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3'')-Ib"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(9588..10403)
                     /gene="sul2"
                     /locus_tag="NL690_RS24395"
                     /old_locus_tag="NL690_24395"
     ARG             complement(9592..10403)
                     /name="sul2"
                     /gene="sul2"
                     /gene_name="sulfonamide-resistant dihydropteroate synthase
                     Sul2"
                     /tool="amrfinderplus"
                     /drug_class="SULFONAMIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(7892..8724)
                     /name="aph(6)-Id"
                     /gene="aph(6)-Id"
                     /gene_name="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          complement(4039..4194)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="2.28e-76"
     Typing          complement(471..1292)
                     /name="IncQ1"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="96.0"
                     /evalue="0.0"
     Typing          complement(1824..3949)
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 cagcagccga aacccctgcc gcttgcggcc attctgggcg atgatggata ccttccaaag
       61 gcgctcgatg cagtcctgta tgtgcttgag cgccccacca ctatcgacct ctgccccgat
      121 ttcctttgcc agcgcccgat agctaccttt gaccaccatg gcatcagcgg tgacggcctc
      181 ccacttgggt tccaggaaca gccggagctg ccgtccgcct tcggtcttgg gttccgggcc
      241 aagcactagg ccattaggcc cagccatggc caccagccct tgcaggatgc gcagatcatc
      301 agcgcccagc ggctccgggc cgctgaactc gatccgcttg ccgtcgccgt agtcatacgt
      361 cacgtccagc ttgctgcgct tgcgctcgcc ccgcttgagg gcacggaaca ggccgggggc
      421 cagacagtgc gccgggtcgt gccggacgtg gctgaggctg tgcttgttct taggcttcac
      481 cacggggcac ccccttgctc ttgcgctgcc tctccagcac ggcgggcttg agcaccccgc
      541 cgtcatgccg cctgaaccac cgatcagcga acggtgcgcc atagttggcc ttgctcacac
      601 cgaagcggac gaagaaccgg cgctggtcgt cgtccacacc ccattcctcg gcctcggcgc
      661 tggtcatgct cgacaggtag gactgccagc ggatgttatc gaccagtacc gagctgcccc
      721 ggctggcctg ctgctggtcg cctgcgccca tcatggccgc gcccttgctg gcatggtgca
      781 ggaacacgat agagcacccg gtatcggcgg cgatggcctc catgcgaccg atgacctggg
      841 ccatggggcc gctggcgttt tcttcctcga tgtggaaccg gcgcagcgtg tccagcacca
      901 tcaggcggcg gccctcggcg gcgcgcttga ggccgtcgaa ccactccggg gccatgatgt
      961 tgggcaggct gccgatcagc ggctggatca gcaggccgtc agccacggct tgccgttcct
     1021 cggcgctgag gtgcgcccca agggcgtgca ggcggtgatg aatggcggtg ggcgggtctt
     1081 cggcgggcag gtagatcacc gggccggtgg gcagttcgcc cacctccagc agatccggcc
     1141 cgcctgcaat ctgtgcggcc agttgcaggg ccagcatgga tttaccggca ccaccgggcg
     1201 acaccagcgc cccgaccgta ccggccacca tgttgggcaa aacgtagtcc agcggtggcg
     1261 gcgctgctgc gaacgcctcc agaatattga taggcttatg ggtagccatt gattgcctcc
     1321 tttgcaggca gttggtggtt aggcgctggc ggggtcacta cccccgccct gcgccgctct
     1381 gagttcttcc aggcactcgc gcagcgcctc gtattcgtcg tcggtcagcc agaacttgcg
     1441 ctgacgcatc cctttggcct tcatgcgctc ggcatatcgc gcttggcgta cagcgtcagg
     1501 gctggccagc aggtcgccgg tctgcttgtc cttttggtct ttcatatcag tcaccgagaa
     1561 acttgccggg gccgaaaggc ttgtcttcgc ggaacaagga caaggtgcag ccgtcaaggt
     1621 taaggctggc catatcagcg actgaaaagc ggccagcctc ggccttgttt gacgtataac
     1681 caaagccacc gggcaaccaa tagcccttgt cacttttgat caggtagacc gaccctgaag
     1741 cgcttttttc gtattccata aaaccccctt ctgtgcgtga gtactcatag tataacaggc
     1801 gtgagtacca acgcaagcac tacatgctga aatctggccc gcccctgtcc atgcctcgct
     1861 ggcggggtgc cggtgcccgt gccagctcgg cccgcgcaag ctggacgctg ggcagaccca
     1921 tgaccttgct gacggtgcgc tcgatgtaat ccgcttcgtg gccgggcttg cgctctgcca
     1981 gcgctgggct ggcctcggcc atggccttgc cgatttcctc ggcactgcgg ccccggctgg
     2041 ccagcttctg cgcggcgata aagtcgcact tgctgaggtc atcaccgaag cgcttgacca
     2101 gcccggccat ctcgctgcgg tactcgtcca gcgccgtgcg ccggtggcgg ctaagctgcc
     2161 gctcgggcag ttcgaggctg gccagcctgc gggccttctc ctgctgccgc tgggcctgct
     2221 cgatctgctg gccagcctgc tgcaccagcg ccgggccagc ggtggcggtc ttgcccttgg
     2281 attcacgcag cagcacccac ggctgataac cggcgcgggt ggtgtgcttg tccttgcggt
     2341 tggtgaagcc cgccaagcgg ccatagtggc ggctgtcggc gctggccggg tcggcgtcgt
     2401 actcgctggc cagcgtccgg gcaatctgcc cccgaagttc accgcctgcg gcgtcggcca
     2461 ccttgaccca tgcctgatag ttcttcgggc tggtttccac taccagggca ggctcccggc
     2521 cctcggcttt catgtcatcc aggtcaaact cgctgaggtc gtccaccagc accagaccat
     2581 gccgctcctg ctcggcgggc ctgatataca cgtcattgcc ctgggcattc atccgcttga
     2641 gccatggcgt gttctggagc acttcggcgg ctgaccattc ccggttcatc atctggccgg
     2701 tggtggcgtc cctgacgccg atatcgaagc gctcacagcc catggccttg agctgtcggc
     2761 ctatggcctg caaagtcctg tcgttcttca tcgggccacc aagcgcagcc agatcgagcc
     2821 gtcctcggtt gtcagtggcg tcaggtcgag caagagcaac gatgcgatca gcagcaccac
     2881 cgtaggcatc atggaagcca gcatcacggt tagccatagc ttccagtgcc acccccgcga
     2941 cgcgctccgg gcgctctgcg cggcgctgct cacctcggcg gctacctccc gcaactcttt
     3001 ggccagctcc acccatgccg cccctgtctg gcgctgggct ttcagccact ccgccgcctg
     3061 cgcctcgctg gcctgctggg tctggctcat gacctgccgg gcttcgtcgg ccagtgtcgc
     3121 catgctctgg gccagcggtt cgatctgctc cgctaactcg ttgatgcctc tggatttctt
     3181 cactctgtcg attgcgttca tggtctattg cctcccggta ttcctgtaag tcgatgatct
     3241 gggcgttggc ggtgtcgatg ttcagggcca cgtctgcccg gtcggtgcgg atgccccggc
     3301 cttccatctc caccacgttc ggccccaggt gaacaccggg caggcgctcg atgccctgcg
     3361 cctcaagtgt tctgtggtca atgcgggcgt cgtggccagc ccgctctaat gcccggttgg
     3421 catggtcggc ccatgcctcg cgggtctgct caagccatgc cttgggcttg agcgcttcgg
     3481 tcttctgtgc cccgcccttc tccggggtct tgccgttgta ccgcttgaac cactgagcgg
     3541 cgggccgctc gatgccgtca ttgatccgct cggagatcat caggtggcag tgcgggttct
     3601 cgccgccacc ggcatggatg gccagcgtat acggcaggcg ctcggcacca gtcaggtgct
     3661 gggcgaactc ggacgccagc gccttctgct ggtcgagggt cagctcgacc ggcagggcaa
     3721 attcgacctc cttgaacagc cgcccattgg cgcgttcata caggtcggca gcatcccagt
     3781 agtcggcggg ccgctcgacg aactccggca tgtgcccgga ttcggcgtgc aagacttcat
     3841 ccatgtcgcg ggcatacttg ccttcgcgct ggatgtagtc ggccttggcc ctggccgatt
     3901 ggccgcccga cctgctgccg gttttcgccg taaggtgata aatcgccatg ctgcctcgct
     3961 gttgcttttg cttttcggct ccatgcaatg gccctcggag agcgcaccgc ccgaagggtg
     4021 gccgttaggc cagtttctcg aagagaaacc ggtaagtgcg ccctccccta caaagtaggg
     4081 tcgggattgc cgccgctgtg cctccatgat agcctacgag acagcacatt aacaatgggg
     4141 tgtcaagatg gttaagggga gcaacaaggc ggcggatcgg ctggccaagc tcgaagaaca
     4201 acgagcgcga atcaatgccg aaattcagcg ggtgcgggca agggaacagc agcaagagcg
     4261 caagaacgaa acaaggcgca aggtgctggt gggggccatg attttggcca aggtgaacag
     4321 cagcgagtgg ccggaggatc ggctcatggc ggcaatggat gcgtaccttg aacgcgacca
     4381 cgaccgcgcc ttgttcggtc tgccgccacg ccagaaggat gagccgggct gaatgatcga
     4441 ccgagacagg ccctgcgggg ctgcacacgc gcccccaccc ttcgggtagg gggaaaggcc
     4501 gctaaagcgg ctaaaagcgc tccagcgtat ttctgcgggg tttggtgtgg ggtttagcgg
     4561 gctttgcccg cctttccccc tgccgcgcag cggtggggcg gtgtgtagcc tagcgcagcg
     4621 aatagaccag ctatccggcc tctggccggg catattgggc aagggcagca gcgccccaca
     4681 agggcgctga taaccgcgcc tagtggatta ttcttagata atcatggatg gatttttcca
     4741 acaccccgcc agcccccgcc cctgctgggt ttgcaggttt gggggcgtga cagttattgc
     4801 aggggttcgt gacagttatt gcaggggggc gtgacagtta ttgcaggggt tcgtgacagt
     4861 tagtacggga gtgacgggca ctggctggca atgtctagca acggcaggca tttcggcgag
     4921 atccgattgt cggccctgaa gaaagctcca gagatgttcg ggtccgttta cgagcacgag
     4981 gagaaaaagc ccatggaggc gttcgctgaa cggttgcgag atgccgtggc attcggcgcc
     5041 tacatcgacg gcgagatcat tgggctgtcg gtcttcaaac aggaggacgg ccccaaggac
     5101 gctcacaagg cgcatctgtc cggcgttttc gtggagcccg aacagcgagg ccgaggggtc
     5161 gccggtatgc tgctgcgggc ggtgatagac tatggccgcg agcatgtgga gcagatcatg
     5221 ctgacggttg cggaagggaa cgaagccgct ataaacctct atcagcgatc ggctcgttgc
     5281 cctgcgccgc tccaaagccc gcgacgcagc gccggcaggc agagcaagta gagggcagcg
     5341 cctgcaatcc atgcccaccc gttccacgtt gttatagaag ccgcatagat cgccgtgaag
     5401 aggaggggtc cgacgatcga ggtcaggctg gtgagcgccg ccagtgagcc ttgcagctgc
     5461 ccctgacgtt cctcatccac ctgcctggac aacattgctt gcagcgccgg cattccgatg
     5521 ccacccgaag caagcaggac catgatcggg aacgccatcc atccccgtgt cgcgaaggca
     5581 agcaggatgt agcctgtgcc gtcggcaatc attccgagca tgagtgcccg cctttcgccg
     5641 agccgggcgg ctacagggcc ggtgatcatt gcctgggcga gtgaatgcag aatgccaaat
     5701 gcggcaagcg aaatgccgat cgtggtcgcg tcccagtgaa agcgatcctc gccgaaaatg
     5761 acccaaagcg cggccggcac ctgtccgaca agttgcatga tgaagaagac cgccatcagg
     5821 gcggcgacga cggtcatgcc ccgggcccac cggaacgaag cgagcgggtt gagagcctcc
     5881 cggcgtaacg gccggcgttc gcctttgtgc gactccggca aaaggaaaca gcccgtcagg
     5941 aaattgaggc cgttcaaggc tgccgcggcg aagaacggag cgtgggggga gaaaccgccc
     6001 atcagcccac cgagcacagg tcccgcgacc atcccgaacc cgaaacaggc gctcatgaag
     6061 ccgaagtgcc gcgcgcgctc atcgccatca gtgatatcgg caatataagc gccggctacc
     6121 gccccagtcg ccccggtgat gccggccacg atccgcccga tatagagaac ccaaaggaaa
     6181 ggcgccgtcg ccatgatggc gtagtcgaca gcagcgccgg ccagcgagac gagcaagacc
     6241 ggccgccgcc cgaaacgatc cgacagcgcg cccagcacag gtgcgcaggc aaattgcatc
     6301 aacgcataca gcgccagcag aatgccatag tgggcggcga cgtcgttcga gtgaaccaga
     6361 tcgcgcagga ggcccggcag caccggcata atcaggccga tgccgacagc gtcgagcgcg
     6421 acagtgctca gaattacgat caggggtctg ttgggtttca cgtctggcct ccggaccagc
     6481 ctccgctggt ccgattgaac gcgcggattc tttatcactg ataagttggt ggacatatta
     6541 tatttatcag tgataaagtg tcaagcatga caaagttgca gccgaataca gtgatccgtg
     6601 ccgccctgga cctgttgaac gaggtcggcg tagacggtct gacgacacgc aaactggcgg
     6661 aacggttggg ggttcagcag ccggcgcttt actggcactt caggaacaag cgggcgctgc
     6721 tcgacgcact ggccgaagcc atgctggcgg agaatcatac gcattcggtg ccgagagccg
     6781 acgacgactg gcgctcattt ctgatcggga atgcccgcag cttcaggcag gcgctgctcg
     6841 cctaccgcga tggcgcgcgc atccattccg gcacgcgacc gggcgcaccg cagatggaaa
     6901 cggccgacgc gcagcttcgc ttcctctgcg aggcgggttt ttcggccggg gacgccgtca
     6961 atgcgctgat gacaatcagc tacttcactg ttggggccgt gcttgaggag caggccggcg
     7021 acagcgatgc cggcgagcgc ggcggcaccg ttgaacaggc tccgctctcg ccgctgttgc
     7081 gggccgcgat agacgccttc gacgaagccg gtccggacgc agcgttcgag cagggactcg
     7141 cggtgattgt cgatggattg gcgaaaagga ggctcgttgt caggaacgtt gaaggaccga
     7201 gaaagggtga cgattgatca ggaccgctca ggaccgctgc cggagcgcaa cccactcact
     7261 acagcagagc catgtagaca acatcccctc cccctttcca ccgcgtcaga cgcccgtagc
     7321 agcccgctac gggctttttc atgccctgcc ctagcgtcca agcctcacgg ccgcgctcgg
     7381 cctctctggc ggccttctgg cgctcctgct gcggcgtccg ctcgtgggcc gtggcgcggg
     7441 tccgcgcgcc ggcctcgtgc gcctggcgct cgcgggcgag gtccagggcg gccgtcttca
     7501 cgttctgcct tgcgcagatg agatagatct agcgtggact caaggctctc gcgaatggct
     7561 cgcgttggaa actttcattg acacttgagg ggcaccgcag ggaaattctc gtccttgcga
     7621 gaaccggcta tgtcgtgctg cgcatcgagc ctgcgccctt ggcttgtctc gcccctctcc
     7681 gcgtcgctac ggggcttcca gcgcctttcc gacgctcacc gggctggttg ccctcgccgc
     7741 tgggctggcg gccgtctatg gccctgcaaa cgcgccagaa aggggtcgtt tgcgggaagg
     7801 ggcggaatcc tacgctaagg ctttggccag cgatattctc cggtgagatt gatgtgttcc
     7861 caggggatag gagaagtcgc ttgatatcta gtatgacgtc tgtcgcacct gcttgatcgc
     7921 ggccgcgata gctagatcgc gttgctcctc ttctccatcc gcgttccaag ctgcggaaag
     7981 gcacccataa gcgtacgcct ggtcgagcag gcgacgcgga tcgacgtcca gcgcacgaga
     8041 gaatgcgtcc gccatctgtg caatgcgtct aggatcgaga caaaggtcgt ctctgtcagc
     8101 cggatcgtag aacatattgg cggcgccaaa gcccacttca ccgaccagac cgacgggatc
     8161 tatcaccagc cagccgcgac tggagaacat gatgttttca tgatgcagat cgccatgtag
     8221 cccacgcagt tccgaggcat tgctcatcat ttgatcggct ataatcgccg cgtggacgta
     8281 gtcagtttga caacctgcgt tttgatcatc gcgcgcccgc tgaaacaaag ctgcaaagcg
     8341 atcccggatc gggagaaggg cagaaggcag gggttcctca gatgcggcat acagcttcgc
     8401 cattagttcc gctgcaattt cggtcgcctg gtagtcgccg tgctcggcaa cgatgtgaga
     8461 gagcattcgc tccccggcat attcgagcaa catcagattg ttctcacgac cgagcaaccg
     8521 gactgctccc ctcccattgc gccataccag atagtcggcc ccgcgcagtt catcagcaat
     8581 gtcttctata ggtttcaatc ccttgacgat tgcaggagtc ccgtctggca atgaaacttt
     8641 ccaaacgagg ctggaaaagg tgtccgcaat gagaacaggt tgcgaaacgt gccaatgagc
     8701 aggaaaaaca ggcggcatga acatcaaccc caagtcagag ggtccaatcg cagatagaag
     8761 gcaaggcgtt cgcggtcggg ggcttcgatc cccaatacat tgaataggac agcgaaggcg
     8821 cgctctgctt catctggcgc tgcccagttc tcttcggcgt tagcaatcat gagtgccaaa
     8881 tcggcatagc gatctgctgt tccgagccgc ccaaggtcga tcagacccgt gcattgaaga
     8941 gttttagggt ccaccatgaa gttcggcatg cagggatcac catggcaaac aaccatatcg
     9001 gtgcgctctt ggtcgagccg caccggtagc tctcgttcga cacgagccaa aagatcgagc
     9061 tgcggcgtac tcttgtcctc gtccggtaag aagtcgggat tgacggcatt gcgggacacc
     9121 acatcaacgg cgcgtccgaa cattcgcgac agcctgcgct caaacggaca ttgatcaacc
     9181 gataggctgt gaacagcgcc aagttgctgc cccattgacg gccacgcttt gagcaaatcc
     9241 gctccagaca gatcagccgc cggtactccc ggaattgccg ttatcaccaa gcatgcaccc
     9301 tcctgttcct cctgccagtt gatgacctcg gggcaagcca cacctcgacc tttgagccaa
     9361 atgaggcggt cacgctctcc agcgagctca ccgcggcggg aagcaggtgc gattttcgcg
     9421 aaggcatgcc cgtcaccacg tcgaaaaaca aaatcaccag attctccgcc tctgacaggc
     9481 aaccagtcag aatgcgattc accaaaaaaa atattagttc gattcaatgg aggttccttc
     9541 agttttctga tgaagcgcga atatagagaa atatcccgaa tgtgcagtta acgaattctt
     9601 gcggtttctt tcagcgccgc caataccgcc agcccgtcgc gcaaggggcg cggctcgtgt
     9661 gtgcggatga agtcagctcc acctgcggcg gcggcaagct ctgcagcgag tgtcgcggcc
     9721 ccgacatccc ccggaccacg gcctgtgagc gcgcgcagaa aggatttgcg cgaaacagac
     9781 agaagcaccg gcaaatcgaa gcgcagccgc aattcatcga accgcgccag caccgagagc
     9841 gaggtttcgg gagcagcccc cagaaaaaac cccatgccgg gatcaaggac aaggcggttg
     9901 cgtttgatac cggcacccgt cagcgccgcg atgcgcgcgt caaagaacgc cgcaatgtga
     9961 tccatgatgt cgccagcggg tgcctcgcgc cgatctgcct gcccgtcttg caccgaatgc
    10021 ataacgacga gtttggcaga tgatttcgcc aattgcggat agaacgcagc gtctggaaaa
    10081 ccgcgaatat cattgagata ggccacacca cgcgacaagg cataggcttg cgtcgcgggt
    10141 tgataactgt cgagcgagac gggaatgcca tctgccttga gcgcgtccag caccggcgcg
    10201 atacgcgcga tttctgtgtc ggacgaaaca ggcgcggcgt cgggattgct ggatgccgga
    10261 ccgaggtcga tcacatctgc cccctcggcc atcagcttac gcgcctgcgc aatggctgcg
    10321 tctggcgcca gataccggcc tccatcggag aaactgtccg aggttatgtt gacgatgccg
    10381 aaaatgatga gcgatttatt catgggggct tctataataa taataatcga gcatgagtat
    10441 catacggatg ctcgggtcga aagggaatcc ccaggcgagt aacctgtttg cggtgatcca
    10501 ttagctgcag gagcagaaga gcatacatct ggaagcaaag ccaggaaagc ggcctatgga
    10561 gctgtgcggc agcgctcagt aggcaatttt tcaaaatatt gttaagcctt ttctgagcat
    10621 ggtatttttc atggtattac caattagcag gaaaataagc cattgaatat aaaagataaa
    10681 aatgtcttgt ttacaataga gtgggggggg gtcagcctgc cgccttgggc cgggtgatgt
    10741 cgtacttgcc cgccgcgaac tcggttaccg tccagcccag cgcgaccagc tccggcaacg
    10801 cctcgcgcac ccgctggcgg cgcttgcgca tggtcgaacc actggcctct gacggccaga
    10861 catagccgca caaggtatct atggaagcct tgccggtttt gccggggtcg atccagccac
    10921 acagccgctg gtgcagcagg cgggcggttt cgctgtccag cgcccgcacc tcgtccatgc
    10981 tgatgcgcac atgctggccg ccacccatga cggcctgcgc gatcaagggg ttcagggcca
    11041 cgtacaggcg cccgtccgcc tcgtcgctgg cgtactccga
//
