LOCUS       NZ_CP099503            24655 bp    DNA     circular CON 21-MAY-2024
DEFINITION  Staphylococcus aureus strain JL42 plasmid pJL42, complete sequence.
ACCESSION   NZ_CP099503
VERSION     NZ_CP099503.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN15964476
            Assembly: GCF_020702535.2
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 24655)
  AUTHORS   Zou,G., Matuszewska,M., Jia,M., Zhou,J., Ba,X., Duan,J., Zhang,C.,
            Zhao,J., Tao,M., Fan,J., Zhang,X., Jin,W., Cui,T., Zeng,X., Jia,M.,
            Qian,X., Huang,C., Zhuo,W., Yao,Z., Zhang,L., Li,S., Li,L.,
            Huang,Q., Wu,B., Chen,H., Tucker,A.W., Grant,A.J., Holmes,M.A. and
            Zhou,R.
  TITLE     A Survey of Chinese Pig Farms and Human Healthcare Isolates Reveals
            Separate Human and Animal Methicillin-Resistant Staphylococcus
            aureus Populations
  JOURNAL   Adv Sci (Weinh) 9 (4), e2103388 (2022)
   PUBMED   34894204
REFERENCE   2  (bases 1 to 24655)
  AUTHORS   Zhou,R. and Zou,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2022) College of Veterinary Medicine, Huazhong
            Agricultural University, Shizishan Street No.1, Wuhan, Hubei 430070,
            China
REFERENCE   3  (bases 1 to 24655)
  AUTHORS   Zou,G. and Zhou,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2020) College of Veterinary Medicine, Huazhong
            Agricultural University, Shizishan Street No. 1, Wuhan, Hubei
            430070, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.14
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 500.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_020702535.2-RS_2024_05_21
            Annotation Date                   :: 05/21/2024 04:13:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,691
            CDSs (total)                      :: 2,609
            Genes (coding)                    :: 2,524
            CDSs (with protein)               :: 2,524
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 85
            CDSs (without protein)            :: 85
            Pseudo Genes (ambiguous residues) :: 0 of 85
            Pseudo Genes (frameshifted)       :: 48 of 85
            Pseudo Genes (incomplete)         :: 36 of 85
            Pseudo Genes (internal stop)      :: 24 of 85
            Pseudo Genes (multiple problems)  :: 20 of 85
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP099503.1.
            Bacteria and source DNA available from Huazhong Agricultural
            University.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24655
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="JL42"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pJL42"
                     /geo_loc_name="China:Hubei"
                     /collection_date="2017"
                     /collected_by="Jianli People's Hospital"
     gene            complement(198..293)
                     /locus_tag="LPT17_RS13265"
                     /old_locus_tag="LPT17_13265"
     CDS             complement(198..293)
                     /locus_tag="LPT17_RS13265"
                     /old_locus_tag="LPT17_13265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001002795.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGYWLHKRDKK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            442..627
                     /locus_tag="LPT17_RS13270"
                     /old_locus_tag="LPT17_13270"
     CDS             442..627
                     /locus_tag="LPT17_RS13270"
                     /old_locus_tag="LPT17_13270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466617.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSAWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(843..1586)
                     /locus_tag="LPT17_RS13275"
                     /old_locus_tag="LPT17_13275"
     CDS             complement(843..1586)
                     /locus_tag="LPT17_RS13275"
                     /old_locus_tag="LPT17_13275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            2012..2995
                     /locus_tag="LPT17_RS13280"
                     /old_locus_tag="LPT17_13280"
     CDS             2012..2995
                     /locus_tag="LPT17_RS13280"
                     /old_locus_tag="LPT17_13280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            <3015..3304
                     /locus_tag="LPT17_RS13285"
                     /old_locus_tag="LPT17_13285"
                     /pseudo=""
     CDS             <3015..3304
                     /locus_tag="LPT17_RS13285"
                     /old_locus_tag="LPT17_13285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            3851..4000
                     /locus_tag="LPT17_RS13290"
                     /old_locus_tag="LPT17_13290"
     CDS             3851..4000
                     /locus_tag="LPT17_RS13290"
                     /old_locus_tag="LPT17_13290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(4168..4860)
                     /locus_tag="LPT17_RS13295"
                     /old_locus_tag="LPT17_13295"
     CDS             complement(4168..4860)
                     /locus_tag="LPT17_RS13295"
                     /old_locus_tag="LPT17_13295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            4970..5164
                     /locus_tag="LPT17_RS13300"
                     /old_locus_tag="LPT17_13300"
     CDS             4970..5164
                     /locus_tag="LPT17_RS13300"
                     /old_locus_tag="LPT17_13300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            6281..6898
                     /gene="cadD"
                     /locus_tag="LPT17_RS13305"
                     /old_locus_tag="LPT17_13305"
     ARG             6282..6895
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            6917..7264
                     /locus_tag="LPT17_RS13310"
                     /old_locus_tag="LPT17_13310"
     CDS             6917..7264
                     /locus_tag="LPT17_RS13310"
                     /old_locus_tag="LPT17_13310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_096002315.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEVF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            7421..7513
                     /locus_tag="LPT17_RS13315"
                     /old_locus_tag="LPT17_13315"
     CDS             7421..7513
                     /locus_tag="LPT17_RS13315"
                     /old_locus_tag="LPT17_13315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(7685..8656)
                     /locus_tag="LPT17_RS13320"
                     /old_locus_tag="LPT17_13320"
     CDS             complement(7685..8656)
                     /locus_tag="LPT17_RS13320"
                     /old_locus_tag="LPT17_13320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            8780..9199
                     /locus_tag="LPT17_RS13325"
                     /old_locus_tag="LPT17_13325"
     CDS             8780..9199
                     /locus_tag="LPT17_RS13325"
                     /old_locus_tag="LPT17_13325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(9726..10571)
                     /gene="blaZ"
                     /locus_tag="LPT17_RS13330"
                     /old_locus_tag="LPT17_13330"
     ARG             complement(9730..10571)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            10678..12435
                     /gene="blaR1"
                     /locus_tag="LPT17_RS13335"
                     /old_locus_tag="LPT17_13335"
     ARG             10679..12432
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            12425..12805
                     /gene="blaI"
                     /locus_tag="LPT17_RS13340"
                     /old_locus_tag="LPT17_13340"
     ARG             12426..12802
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            13069..13662
                     /locus_tag="LPT17_RS13345"
                     /old_locus_tag="LPT17_13345"
     CDS             13069..13662
                     /locus_tag="LPT17_RS13345"
                     /old_locus_tag="LPT17_13345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            13634..15076
                     /locus_tag="LPT17_RS13350"
                     /old_locus_tag="LPT17_13350"
     CDS             13634..15076
                     /locus_tag="LPT17_RS13350"
                     /old_locus_tag="LPT17_13350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /protein_id="WP_000790712.1"
                     /translation="MKNKEKYLTNFSEAKRKKATQKYNIIKPFILGEQSLSSISKSKGI
                     ALSTLYRWNKSYKEQGLKGLIYATKADKGTRKIEPKIIDEIERLALMNKRNSIATIHRK
                     TTNYCKENNFDIPSYKQIYSVIKAMPKSVIDFSHQGEKYYQNKYDLIQIRESSRPNEIW
                     QADHTLLDIFILDQKGNINRPWLTIIMDDYSRAIAGYFLSFDAPNAQNTALTLHQAIWN
                     KNDTNWPVCGIPEKFYTDHGSDFTSHHMEQVAIDLKINLMFSKVGVPRGRGKIERFFQT
                     VNQTFLEQLPGYINNNDTPSNLINFHNFEEKLRYFLIEDYNQKEHSTIHTTPISRWNSN
                     HFFPNMPSSLEQLDLLLLEIPKSRKVHSDGIHFQGFRYSNTNLAAYVGEYVLIRYNPND
                     MAEIRVFYRDEFLCTAICPEIADYSIDIKDIQHARSQRRKHLKQNIASPSTTELIKEEK
                     NCGYSPQETTKNVKKLKRYRND"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            15069..15827
                     /locus_tag="LPT17_RS13355"
                     /old_locus_tag="LPT17_13355"
     CDS             15069..15827
                     /locus_tag="LPT17_RS13355"
                     /old_locus_tag="LPT17_13355"
                     /inference="COORDINATES: protein motif:HMM:NF012464.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000164959.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYTAPAEKQSGKSIENRPVFQEVLN
                     FLRMGDRLIVESIDRLGRNYEEIIQTVNYLKDKEVQLMITSLPMMNEVIGNPLLDKFMK
                     DLIIQILAMISEQERNESKRRQAQGIQVAKEKGIYKGRPVLYSPNAKDPQKRLVYYRVV
                     ELLEQGKSISTIAKEVGITRQTIYRIKNSK"
                     /name="recombinase family protein"
     gene            15888..16202
                     /gene="arsR"
                     /locus_tag="LPT17_RS13360"
                     /old_locus_tag="LPT17_13360"
     ARG             15889..16199
                     /name="arsR"
                     /gene="arsR"
                     /gene_name="As(III)-sensing metalloregulatory
                     transcriptional repressor ArsR"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="99.04"
                     /coverage="100.0"
     gene            16199..17491
                     /gene="arsB"
                     /locus_tag="LPT17_RS13365"
                     /old_locus_tag="LPT17_13365"
     ARG             16203..17488
                     /name="arsB"
                     /gene="arsB"
                     /gene_name="arsenite efflux transporter membrane subunit
                     ArsB"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="99.77"
                     /coverage="100.0"
     gene            17509..17904
                     /locus_tag="LPT17_RS13370"
                     /old_locus_tag="LPT17_13370"
     CDS             17509..17904
                     /locus_tag="LPT17_RS13370"
                     /old_locus_tag="LPT17_13370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent arsenate reductase"
                     /protein_id="WP_000358995.1"
                     /translation="MDKKTIYFICTGNSCRSQMAEGWGKEILGEGWNVYSAGIETHGVN
                     PKAIEAMKEVDIDISNHTSDLIDNDILKQSDLVVTLCSDADNNCPILPPNVKKEHWGFD
                     DPAGKEWSEFQRVRDEIKLAIEKFKLR"
                     /name="thioredoxin-dependent arsenate reductase"
     gene            18284..18577
                     /locus_tag="LPT17_RS13375"
                     /old_locus_tag="LPT17_13375"
     CDS             18284..18577
                     /locus_tag="LPT17_RS13375"
                     /old_locus_tag="LPT17_13375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            18652..20586
                     /locus_tag="LPT17_RS13380"
                     /old_locus_tag="LPT17_13380"
     CDS             18652..20586
                     /locus_tag="LPT17_RS13380"
                     /old_locus_tag="LPT17_13380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713731.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTTIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLTLKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTPDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            20590..20901
                     /locus_tag="LPT17_RS13385"
                     /old_locus_tag="LPT17_13385"
     CDS             20590..20901
                     /locus_tag="LPT17_RS13385"
                     /old_locus_tag="LPT17_13385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            20913..21539
                     /locus_tag="LPT17_RS13390"
                     /old_locus_tag="LPT17_13390"
     CDS             20913..21539
                     /locus_tag="LPT17_RS13390"
                     /old_locus_tag="LPT17_13390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            21777..22420
                     /gene="mobV"
                     /locus_tag="LPT17_RS13395"
                     /old_locus_tag="LPT17_13395"
                     /pseudo=""
     CDS             21777..22420
                     /gene="mobV"
                     /locus_tag="LPT17_RS13395"
                     /old_locus_tag="LPT17_13395"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            22487..22987
                     /locus_tag="LPT17_RS13400"
                     /old_locus_tag="LPT17_13400"
     CDS             22487..22987
                     /locus_tag="LPT17_RS13400"
                     /old_locus_tag="LPT17_13400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273007.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTYFEKYTKQIKAAQMILD
                     DYEWIKSGKSLKKSEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQE"
                     /name="hypothetical protein"
     gene            23350..24210
                     /locus_tag="LPT17_RS13405"
                     /old_locus_tag="LPT17_13405"
     CDS             23350..24210
                     /locus_tag="LPT17_RS13405"
                     /old_locus_tag="LPT17_13405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            24297..24638
                     /locus_tag="LPT17_RS13410"
                     /old_locus_tag="LPT17_13410"
     CDS             24297..24638
                     /locus_tag="LPT17_RS13410"
                     /old_locus_tag="LPT17_13410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761344.1"
                     /translation="MKLAEAIKEQRELKRWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRAPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     ARG             17510..17901
                     /name="arsC"
                     /gene="arsC"
                     /gene_name="thioredoxin-dependent arsenate reductase"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(9727..10571)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="97.15"
                     /coverage="100.0"
     BGC             13284..23577
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          3361..3508
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(844..1586)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          2013..2995
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          3127..3296
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
     Typing          23351..24210
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          21778..22151
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.2"
                     /coverage="100.0"
                     /evalue="1.03e-73"
ORIGIN
        1 aatgcacatc aggcaatatg aaaaaggaaa gtatttttac gacaccttga aatgtattga
       61 taagaataga agagtttaca aaaggcaata tgaaatatat actaaaagta acaagaattt
      121 cgtttgtaaa cgcaccaaac cccgaactat tcgccgtagt tcggggtttt ttggtgaatt
      181 ggctttaatc gtctatatta ttttttatca cgtttatgga gccaataacc aaataacgta
      241 acgagacaac cactgattgc cgttgtcatg atgtgaacaa gaatttcatt cataaatcgc
      301 acctcctctc tacgccgaat tgacgtctga gagatagacg accttcacat tataacaaat
      361 ctcttcttcc atgaaataac atgaatatta ataaatgttg ttatatatta aagataaata
      421 aatataaggg tgggattgat aatgtttggc gatcaaagac aagaagctac aaaatatgtc
      481 attaaagaag gttatcaaga tatttatttc ctcaacaaaa acggggaatg gtattatttc
      541 gaagtaagaa gtgcctggcg tggcaaacat attattagag ttaaagatgg tttgttaggt
      601 tggagaaaag aaatagtaac tgaataaaga tacaaaatac ttgccaatgc aaaagaatga
      661 aaacgcgtca aatcaacgat gtataaaaga tgcataaaag ataatgaaag taaaaagcca
      721 taaatgccta tatgacggca tttatggctt tttgtttggt taacataatc gatgattacc
      781 agaagttctc actatataaa agacactaaa attttataac ttttagtgcc taatcaatta
      841 ttttagctac caaacaaacg actccaaaac ccctttttag gttccgtttc ttcactcttt
      901 tcttctatat cactatcatt gtcatttaga ttagctggaa cgtcttcttt ttttgcttct
      961 tcaccttgtg tactttcgtc gctttgactt ccagatatat ccttatattg aatctctgtt
     1021 tctttagttt cttcctgatc tctgttaata tttacaggat tagtagtata tgttttttct
     1081 tgtgcatcaa cgttttgtct agtgttagta gatgtatcaa agggataatt aaggtgtttt
     1141 tctttttcta attgattttc taatttttga atctttttat tactctctaa tgccagaact
     1201 tgctgatttt caagcaattt tgatctttct tgcaactctt ttctgtaaaa ttcaattgtt
     1261 gtttcatgac gactttcttg tttttcaatt tgattattta aagtatcaat ctgattttta
     1321 aggatttcta ctatttgagc atcgcttttc gattcaaaat taatattatc cgaccctttt
     1381 ttttgtttgt cttcagtagt actttcaaaa ccatatttct ttttattttc atttactctt
     1441 tgaatgattt tttctatatc ggtatcttct ttaataaacg aagtgttttc ctgttttatt
     1501 gtctctatat tcaatcgctt aatattatta aaaatcgttt gcttactaac ccctaattct
     1561 tcactcaact ttttcacact tttcatatca tcaacccttt ataaaatgtt tataaaccct
     1621 tgataaaata ttataagctt ataatgctta ataataaagt gattaataaa taaaaataaa
     1681 catccatcaa cctttttatc aagggtttat gaaaggttta tgatatttat caagggttta
     1741 taaacccttg ataaagctat attttccctt ttataagttt atttaaagtg ctataataaa
     1801 cttaatataa caaaaacccc aactactggt aatagtcggg gtttggtaat aaaacgttta
     1861 gaaactgttt atttatataa ttttcgatac ttgtattata taatgaataa tatcttagtg
     1921 caagcaccta aatcattaaa taaatgtaaa gctaaataaa aacgttttat tacctcttac
     1981 caaactaaaa tatggaaaga ggttttttgt catgcaaaat caatatttta cagtgcaaga
     2041 aaattacaaa gaaagatttt atcaaatccc taaagtattc tttaccagtg aaaattataa
     2101 aaatctaact aatgatatga aaatagccta tgctatctta cgtgatcgct taaatttatc
     2161 tattaaaaat agctgggttg atgaagatgg taacatttac tttgtttatt caaatgaaaa
     2221 gctaatggaa atcttaaatt gtaaaaaaga aaagttaaca aaaataaaaa aagggttaga
     2281 aaacgatggt ctactcattc aaaaacgacg tggtttaaat aaaccaaata ttctatattt
     2341 aatgaaacct attgtcacag aacgtgatat ttacaaaata gaaaaagaag aaaacgatgt
     2401 tgaaccttac ggcgagaagg aagttcgaaa atcgaacgtc cagaagttcg aaaatcgaac
     2461 gtccagaagt tcgaaaatcg aacgtccaga agttcgaaaa tcgaacacta atgatactga
     2521 ctttaatgac attgacttta atgatactga gaataatgat atgaatgact tgaatgatat
     2581 aaagtacaaa aatgaaatta gtaatcattc aaatcattca aatcaattta cacataattt
     2641 tgatgataaa gaaatgctat tgcaagaatt cccagaacaa ctaactaatt atttattaaa
     2701 atatgattat agagatttag aaatcataaa ggctgttatt cttaaagcaa aaaaatcatt
     2761 taattcaagg catgaagata tgcattacat gttagaggac attgaggatg aaatattaac
     2821 ttctttaaaa agacttaaaa aagctataca tgatagggga gttaaaggcc aaaaggaaac
     2881 aatcaagtca atgcaagctt atttaatgca aacaattcta actgaacttg aagaaacaca
     2941 tgccctttat atgcgccgta aaaacatgaa acaatataat atctttaatc aataattcaa
     3001 atgattttat aacactcgaa gagacatcaa aatattccgt taaatcatct gactttttaa
     3061 ctgatgacga cgaaaaaaat caagaaattg taagtgattt agaaaaaggt ttgtatcgaa
     3121 aacgtatgtt aagttatggt ggattgctta aacaaaagca taaaatttta aacttagacg
     3181 atgccgaaga tggtaatttg attaatacaa gtgatgaaga taaaacgaca gacgaagaag
     3241 aaaagcacat tcaattaccg caatttggaa tttcgaaaag caaaattatt atttaagaca
     3301 ttagtgataa ctgatgtctt tttttattgt ttttctgtaa aaaagtgctg tcttattttt
     3361 gtgacaaatg ctgtatgtag tgtcacaaaa gtgtgacact acagctttgt atgatatcac
     3421 tttaaaataa cttaaaaccc ttggaatgtc tggccttgcc agatctatca tttttgaatg
     3481 atagcaaatt tcccttatgc tcttacggag attttagagt taaattaaaa tttctaagtt
     3541 tttgataaga aaagccctgc aggaatttag aaaaacatgg ggaagtttta aagtatttta
     3601 tgctaatttt taaatttgca tgtaaatggg cagtatctaa aaaattagtc actgattttg
     3661 ctgaaatttt tgtttgtgaa attagcatat atttatttgg ctcatatttg cgttttaaga
     3721 gactgtatag atttttaagt acaaaaccta tatgatttgc ctctaagtct tcaaaatgcc
     3781 tcttaaaatc caaaataaaa gtgtttaata ttgtaataag gattgctatt tttataaaag
     3841 gagagatatc atgaagatta aaactttcgc tacttttact catcgtcaat tagataaaca
     3901 agttaatagg tttttaaaga atgatattca tgtattagaa attcaaacac acagtaattg
     3961 gttatatatt tcagctattg ttttttatga ggataaataa ggaacatcgt atttatgccg
     4021 aaaaaattta ttgatgttga gaagaaccct taactaaact tgcagacgaa tgtcggcata
     4081 gcgtgagcta ttaagccgac cattcgacaa gttttgggat tgttaagggt tccgaggctc
     4141 aacgtcaata aaacaattgg aataaaatca acctacagag catccagctg caaatgcagt
     4201 tccgcaaact gcttcacata caccgccggc tattggattt acgattgccc atactccaca
     4261 gtagtgagca catgcataaa gtccagccat actacaagcg aatgctttgc cgttccattt
     4321 gaatcctgca tatgttaccg gtctgttttt atcaactttt tcagccttat attcaacgta
     4381 atttttgtta ataagtattt ttccctcttt gttttcagtc atacttcttt tttcggcaat
     4441 gaattttgtg atttttttgt tgtagttatc atatattgtt tcagaaacta caatttcttt
     4501 tgttttttca tttttataag cgttattagc tatgtagcca tatgcatttt tatcatttgc
     4561 ttctgtagct agatatttta atttagaatt tttgtcttct agctttattt ttttaaatcc
     4621 ttcttttttc atttgctttt cgaatttttg catatcttca tttttatttt gcaattgttc
     4681 tagaaaactt atttctttct tggtcatttg tgatacttcg atgtttttgc ttttcaattt
     4741 ttctttttga ttttctagta aagaactttt ttgttcttca tttgcgtaag cattagaaaa
     4801 attcgcgcta aataccagta ggaacaagga aattattgaa aataatttta taattttcat
     4861 ttgatacctc caagataata agatatttta attgtataag taagcgcttt ataaaatcaa
     4921 tatttatttt aatatattta taaacatatt tttgaaagga gtctatttta tgaatgaaaa
     4981 tttagaaaaa tatataaaaa gtttgccact tttaggtttg ttaattagta ttttgttaat
     5041 tgttttattc ttttttattt tagatgttga tgaagattta ttcgtggttt ttttatactg
     5101 tttattgcct ttgatagtta atttgtctat ttatggtttt tatgtttttg ttaaaagaaa
     5161 gtaagattat gaataatttt gtttttaatt tgtatgcttt gagggggttg gaaaacggta
     5221 ggtgtataga ttagatttct tgtttttttg aaacgagtgt gaacgagttt cttcttgtct
     5281 tgatttttga taaaaacgcc ctacaggaat ttagaaaaac gtggggaagt tttaaagaat
     5341 tttatgctaa tttttaattt gcatgtaaat gggcagtgtc taaaaatagt tattgttttt
     5401 gctcaaattt ttgtttttga aaatagcata tatttatttg gctcatattt gcgttttaaa
     5461 agcatatata agttttagat ataaaactat atgaatcacc cctaaatctt taaaatgccc
     5521 tcttaaaatt caaaataagg gcataaaaaa taaaagctac cccagataaa gtgaggtagc
     5581 tttttctttc atacggtcta tttatttttc tttcgacgcc gtatcgtcga tgtaattcaa
     5641 aaaagttatg ggctataaat ctacatcact ttttcaagaa tgtagtagca atattcaacg
     5701 caaattaatt tttataactg ctcggaatat ctcaagccgt ttctttaatt ttgaaataaa
     5761 aaaatcgacg aaggtcgatt acgtttttgc acatgtcgat ttatccgacg tataagtgcg
     5821 cccttacggg atttaactag attataacga cgaattttag acctgtaaag caataacaat
     5881 taggtctacc aggtagataa agtgtacaaa gtagaaccga aaaagttatt tattttgaag
     5941 atttttcgta gatataattt gctaataaac ttcctaaaac tgaataaaga aaaatagtta
     6001 aactcatgta atcactccat aattctgaag tgtctccatg tctacgcata gacacgcatt
     6061 tatgccgaga aaatttattg tgcgttgaga agaaccctta actaaacttg cagacgaatg
     6121 tcggcatagc gtgagctatt aagccgacca ttcgacaagt tttgggattg ttaagggttc
     6181 cgaggctcaa cgtcaataaa gcaattggaa taaagcacct atgattattt aaaaatataa
     6241 gttataatac attcaaaaat atttttgaat gaggtgtatt atgattcaaa cggttgttgc
     6301 tgctgctgtt ctttatattg ctacagcagt tgatttatta gtaattttat taatattttt
     6361 tgctagagca aagactagaa aagaatatag agatatttat gttggtcaat atttagggtc
     6421 tattatttta atattagtta gtttgttttt agcttttgta ttaaattatg ttccagaaaa
     6481 gtggatatta ggtttattgg gtttaatacc aatttatctt ggaattaaag tggctattta
     6541 tgatgattgt gaaggagaaa agagagctaa aaaagaattg aatgaaaaag gattgtctaa
     6601 attagttggt acggttgcaa ttgttacgat agcaagttgt ggcgccgata atattggttt
     6661 atttgttcca tattttgtga cattaagtgt tactaattta ttacttactc tgtttgtctt
     6721 tttaatttta attttcttct tggtgtttac tgcacaaaaa ttagctaata ttccaggaat
     6781 tggagaaatt gttgagaaat ttagtcgttg gattatggct attatttata tagctttagg
     6841 tttatttatt attattgaaa atgacactat tcaaacaatt ttaggattta tattttaatt
     6901 tagggtgtga ttttatatga gttatgaaaa tacttgtgat gtgatctgtg tacatgagga
     6961 taaagttaac aatgctttaa gttttttaga agatgataaa tctaagaaat tacttaacat
     7021 tttagaaaaa atttgtgatg agaagaaatt gaaaatcata ttatctttga ttaaagaaga
     7081 tgagttgtgt gtttgtgata tttctttgat attgaaaatg agtgttgctt caacttcaca
     7141 tcatttaagg cttttatata aaaatgaggt acttgatttt tataaagatg gaaagatggc
     7201 atattatttt attaaagacg atgaaataag agagtttttc tctaaaaatc atgaggtttt
     7261 ttgaaacgag tttcttcttg tcttgatact ataaaaaaca aagttatata acataagacg
     7321 acttatcgga agtagatatg cttgtatatt cacagatggt ataataatag agtcgcctat
     7381 ctctcaggcg tcaattgacg aagagaggag gtgcattact ttgctaatca ttttcgttca
     7441 catcatagca ccagtcatca gtggctgtgc tgttgcgtat tatacttatt ggcttagtaa
     7501 acgcaacaaa taattaatag gcgactttat aagccagcat cgaaaaaatc cccacactac
     7561 tgcaatagtg tggggattgg tgcattaatt gttaatcatt ttcgttatat aaattataac
     7621 actggttagt agagaaatgc aaaatgattg aattaatagt aaatgtatta atgaatactc
     7681 acacttatac ttttaaaata gttcttccta aatgttgtcc ttttaaaagc tgatctatcg
     7741 ttttatagaa ttcttcaaat ccaatttcat tgtatagaag tgaatttcct atattccatt
     7801 catttgctaa cttactccat atatcttcac ggatattatg atcaacatat acagaatcaa
     7861 tgccaattaa tttaatacct ctaagaataa acggtaatat attagcgtta agtgaatttc
     7921 ctgctacatt tccacataca gtagcaacac cttgataatt tagacgtttt aaaccgtata
     7981 atgttacatt actccccact gtatctaaga aataatcaaa aatacctttt ttaagcggtt
     8041 tattatcatc ttcaattatt attacttgtt ttgcacctaa tttttttgcg atttctattt
     8101 gcttttcttt tcttacgata gcagtgatat tttcatatcc aattttatgt aaaatttgta
     8161 tagcaacact gcccacacca cctgtagccc cagacactaa aatttcaggt tgtgatttga
     8221 tattcattcc atatttttct agttcaaaaa ttgataatgc tgccgtaaaa ccggctgtgc
     8281 catataccat agactcttta atagacattt cttggggaat aggaacaatc cactctccag
     8341 gcacttgtgc atattctgaa aatccacctg tatgtgtcac gccaacatca taaccagtaa
     8401 ctaatacatt atcgccttct ttaaacttat cattcgaact tgattcaaca atacctgcaa
     8461 aatctatacc aggaatcata ggataatctc taattacacc gcctttatat tgtaaagcta
     8521 gcatatcctt ataatttatt gaagagtata ccacttttac taatacatca cccttcgata
     8581 aatgagattc atcaactttt tctactttat aactaacatt tgatgcactt tttctcacta
     8641 ctaccgcatt gaacatttat tagccttctt tcacaattgt tttgtagaag tatgtttttg
     8701 ttgcaaaact attttcctac aaaacttatc atgatatgat aagcgagtca atactaatga
     8761 tttaagagag gttttagttg tggaattaga taattgtata aattatttgt tgagtacttc
     8821 tcagaataga gtttttaaac attttaaaag tttattaagt ccctataata ttactccagc
     8881 agaatatggt gttttgaatt gcttgattaa tagtaatttg aatacaccta aagcgattgg
     8941 taatacttta aatttagaac cttcaacaat atctggaata ttagataaga tgtccaaaaa
     9001 ggatctaata acacgtcaaa ctgataatga aaatagaaga actgtgctaa taaacagtac
     9061 aaataaagca aaagacttat ggccaacatt agaaaagaaa gcctatcaac ttaataatca
     9121 ttacttcgct aatttaacta atgaagaaac tgtagtgttt aaaaagatat tactaaagat
     9181 aaataaaact acgttttaat ttttacgtta ttaaaaagtt gaagtgcgaa ttataatcga
     9241 gtaaatataa atgatagctt agcttaatta tatattaaag ccaactatac ttttattccc
     9301 gaaaaaccta ctatccaaat ttctaagata ctttagcctc tataataaac atattgtaat
     9361 ataatttatg tattatttag gtttacccta atcgaacaat aaaaaaatac ttttaaaatg
     9421 ctattgtcac tttgcttgat atatgagaat tatttaacct tataaatgag aaaaaagcaa
     9481 cgcactttaa ataagatacg ttgctttttc gattgatgaa cacctataat taaactattc
     9541 atctattatt tatgattttt tgtatataca atatttctag tttgttaaag agaattaaga
     9601 aaataaatct cgaaaataat aaagggaaaa tcagtttttg atatcaaaat tatacatgtc
     9661 aacgataata caaaatataa tacaaactat aagatgttat cagtatttat tatgcattta
     9721 gaatattaaa attccttcat tacactcttg gcggtttcac ttatcaactt atcatttggc
     9781 ttatcacttt tattgtcttt attcgtaaaa atgactaaaa caataggttc agattggccc
     9841 ttaggataaa caaaagcaac atcatttcta gaagcatatg ttattgcttg accactttta
     9901 tcagcaacct tatagtcttt tggaacacca tctttaatta aagtgtctcc gtttttatta
     9961 ttaaacatta aatcaagtaa gaaattttta ttttttttgc ttaattttcc atttgcgata
    10021 agtttattta aagtcttgcc gaaagcagca ggcgttgaag tatctttttt gctctttggt
    10081 gaatagtaat ttaattctat ctcatatcta actggatttg ttactttatc tcctagttct
    10141 tttagacgtt gtttaacttt tttgattcca ccgatttctt ttataatttt attgtttgct
    10201 gtattatcac tatatgtcat tgaagcctca ataagttctt ttaaagtgat atcttttcct
    10261 acatattttt ctaaaatagg agaataagca actatatcat ctttgttaat atgtactttt
    10321 ttatttaact tattataagg tacttgttct aacaaaatag cactatttat cgcttttgaa
    10381 gtcgaagcat aggcaaatct cttatctgaa ttaaatttta cttccttacc acttttagta
    10441 tctaaagcat aaacaccaat atgagcatta tatttttttt ctaaatcatt taactctttg
    10501 gcatgtgaac tgtttgaatt acatgcactt aaaactaaag caattacaat taaaaatatt
    10561 aactttttca aaataaaccc tccgatatta cagttgtaat ttttataaat caataatatt
    10621 acaattgtaa tattgatgtc aattgtttat tataaatatt tgaaagaagg tgtcaaaatg
    10681 gctaaattac taataatgag cgtagtaagc ttttgtttta tatttctatt gttagtattt
    10741 tttaggtaca tattaaaacg ctattttaat tatagtttaa attataaagt ttggtatcta
    10801 actatgcttg ctggattaat tccttttatc ccaattaaat tctcttttat aaaatttaat
    10861 aatgtgaata atcaagcgcc cacagttgaa agtaagtcac acgatttgaa ccataacata
    10921 aataccacca aacctattca agagttcaca acagatatcc ataagtttaa ttgggattca
    10981 attgataata tctgcacagt tatttggata gttttagtta ttattttaag ttttaaattt
    11041 ttgaaagcct tattatatct taaatattta aagaaacagt cactttatct aaacgaaaat
    11101 gaaaaaaata aaatagatac gatacttttc aaccatcaat ataaaaaaaa tattgtgatt
    11161 cgaaaagcag aggctattca atctccaata actttttggt atgggaaata tattattttg
    11221 attcctagtt catattttaa aagtgtaatt gataaaagac taaaatatat aatactgcat
    11281 gaatatgctc atgctaaaaa tagagatact ttacatttaa ttatctttaa tatcttctct
    11341 attattatga gttacaatcc attagtacat attgtaaaaa gaaagataat tcatgacaat
    11401 gaagtagaag ccgatagatt tgtccttaat aatattaaca aaaatgaatt taaaacttat
    11461 gcggaatcta ttatggactc cgtattaaaa accccatttt ccaacaaaaa tatattaagc
    11521 cattcattta atggtaaaaa atcattactc aaaagtagat taattaatat aaaagaagcc
    11581 gatctgaaaa agcagtcaaa attaattcta atttttattt gtatttttac tttttttatc
    11641 atgataattc aaagccagtt tttaatgggg caatccttaa ctgattataa ttataaaaag
    11701 cccttacaaa gcgattacca aattttagat gaaagtaaaa attttggttc aaatagtgga
    11761 tctttcgtta tgtacagcat gaagaaagac aaatactata tttataatga aaaagaaagt
    11821 agaaaaagat attctcctga ttcaacttac aaaatttatt tagcactgtt tggacttgac
    11881 cgtcatatta taagtgataa aaattcacgt atgtcatgga atcataaaca ttatcttttc
    11941 gagtcttgga ataaggaaca agatttaaat acagcaatgc aaaattcagt taattggtac
    12001 ttcgaacgta ttagtaatca aataccaaag aactatactg cggctcaact caagcaatta
    12061 aattatggta atgaaaattt gggaagttat aaaagctatt ggatggaaga tagtttgaaa
    12121 atatctaatc ttgaacaagt aatagttttt aaaaatatga tggaacaaaa taaccatttt
    12181 agtaaaaaag caaagaatca attatcttct tcattattga ttaagaaaaa tgaaaagtat
    12241 gaactgtatg ggaaaacagg tacaggtata gtaaacggga agtataataa tgggtggttt
    12301 gtaggttacg taattacaaa tcatgataag tattattttg ctacacattt atcagatgga
    12361 aacccgtctg ggaaaaatgc tgaattaata agtgaaaaaa tattaaaagg aatgggtgtt
    12421 ttaaatgacc aataagcaag ttgaaatatc tatggctgaa tgggatgtta tgaatataat
    12481 atgggataaa aaatcagtat cagctaatga aattgtagtt gaaattcaaa aatataaaga
    12541 agttagtgat aaaacgatta gaacattaat cacaagacta tataaaaaag agattataaa
    12601 acgatacaaa tcagaaaata tttattttta ctcatcaaat attaaagaag acgatattaa
    12661 aatgaaaact gctaaaacct ttcttaataa actgtatgga ggggatatga aaagtttagt
    12721 gctgaatttt gcgaaaaatg aagaattaaa taacaaagaa attgaagaat tgcgagacat
    12781 tttaaatgat attagtaaaa agtaattaga ggtatgtttc aaacataata catatgtaaa
    12841 ccatacttga ctcttattaa attagttttg ttaatgacat ttaaaatata ttattaaaga
    12901 tgagagtgtc cagaaaataa ccattttctg gacactcttc ttttatgtct aaataagtaa
    12961 gaattacata ggattatgtg ttcaaaaacc caacaaaaaa tctatgttca taaaaggcct
    13021 tgtaattaag ttatggtaca ctgaagatgt atataggagg tttgtatttt gaaaataggt
    13081 tatgcaagag tttcaactgg attacaaaat ttaaatttac aggaggatcg attaaataca
    13141 tatggttgtg aaaagatatt taatgaccat atgagtggtt caaaaagtaa aagacctggt
    13201 ttagataaag caattgaatt tgcgaggtca ggagatacga ttgttgtttg gagattagat
    13261 agattgggac gtaatatgga ggatttaatc acattagtta atgagcttaa cgaacgaggt
    13321 gtaagtttcc atagtttaga agaaaatata acaatggata aatcaagttc aactggacaa
    13381 ttattatttc atttattcgc agcatttgca gaatttgaac gtaatttaat tttagagcgt
    13441 tcttcagctg gccgaattgc agcacgtgct agaggccgat atggaggcag accagaaaaa
    13501 ttaaatcaaa aagatttaaa cttacttaag acactttatg ataatggcac gccaattaag
    13561 acaattgcag aacagtggca tgtttcacgt acaacaattt atcgttacct caataaattg
    13621 gaggacaagg aagatgaaaa acaaggagaa gtatctaact aatttttctg aagccaaacg
    13681 taaaaaagct actcaaaagt acaatattat aaaacctttt atcctaggcg aacaatcttt
    13741 atcaagtatt tctaaaagta aagggattgc gttaagcacc ctttatagat ggaataagtc
    13801 atataaagaa caaggactta aaggactaat ctatgcgaca aaagctgata aaggaacacg
    13861 taaaatagaa ccaaagataa ttgatgaaat tgaacgcctt gcgcttatga ataaaagaaa
    13921 tagtatagcc acaattcata ggaaaaccac taattactgt aaagaaaata attttgatat
    13981 accaagttat aaacaaattt atagtgttat taaagcgatg cctaagtctg ttattgattt
    14041 ctctcatcag ggtgaaaaat actatcaaaa taagtacgat ttaatacaaa ttagagaatc
    14101 ctcgagaccc aatgaaatat ggcaagcaga ccatactttg ctagatatct ttatattaga
    14161 ccaaaaaggt aatatcaata gaccatggct aactattatt atggatgact atagtcgtgc
    14221 aattgcaggc tatttcttaa gttttgatgc ccccaatgct caaaacacag cattaacact
    14281 acaccaagca atatggaata aaaatgatac caattggcca gtgtgtggta tacccgaaaa
    14341 attctacaca gatcatggaa gtgactttac ttcacatcat atggaacaag tcgctattga
    14401 tttgaaaatt aacttgatgt tttcgaaagt tggtgttcct cgtggtcgtg gaaaaataga
    14461 acgattcttt cagacagtta atcaaacttt cttagaacaa ctgcctggat atataaacaa
    14521 taatgatact cctagtaatc taataaattt tcacaatttt gaagaaaaat tacgttactt
    14581 tttaattgaa gattataatc aaaaagaaca tagtactatt cataccacgc ctatcagtcg
    14641 ttggaatagt aatcactttt tccctaatat gccgagtagc ttagaacaac ttgatttatt
    14701 attgttggaa atacctaaat ctagaaaagt tcattcagat ggcattcatt ttcaaggttt
    14761 tcgatacagt aatactaatc tagcagctta tgtaggtgaa tatgtactga ttcgttataa
    14821 cccaaatgat atggctgaaa tacgtgtgtt ttatagagat gaatttcttt gtactgctat
    14881 atgtccagaa atagctgatt actccataga tataaaagac atacagcacg ctcgtagtca
    14941 gagaagaaaa cacttaaaac aaaatattgc tagtccaagt accacggaat taattaagga
    15001 agaaaaaaat tgtggttatt cacctcaaga aacgactaaa aacgtcaaaa aattaaagag
    15061 gtatcgtaat gactaaaaat caaaatttca ttgaaacgaa agagtataaa cgctttgctg
    15121 aattttgtga tgcttgtatt aaatatcagt atattggtat atgttatggt caacctggtg
    15181 tcggaaaaac tttatcgtct aggtattaca caaattggga tactattgaa aaacaagtta
    15241 accatagagg ttgggaagat ttagctagta aaacgaccga tgacatacta tcggtggata
    15301 aaatatttta tactgcacca gcagaaaaac aatcaggtaa atctatagaa aacagacctg
    15361 tttttcaaga agtattaaat tttttaagaa tgggagatcg tttaattgtt gaatctattg
    15421 atagactagg aagaaattac gaggaaataa ttcaaacagt taattactta aaagataaag
    15481 aagttcagct catgataacg agtttaccta tgatgaatga agtcattgga aatccactac
    15541 tagataaatt tatgaaagat ttaattattc aaattttagc aatgatttca gaacaagaaa
    15601 gaaatgaaag taaacgtcga caagctcaag ggattcaagt cgccaaagaa aaaggtatat
    15661 ataaagggag acctgttctg tattctccca atgctaaaga cccacaaaag cgtttagttt
    15721 attaccgagt tgttgaatta cttgaacagg gtaaatctat aagtactata gctaaagaag
    15781 ttggtattac acgtcaaact atatatagaa taaaaaatag taaataaagt aacatagaca
    15841 ataatctata tagatgttaa tctatttaat atctaggagg tttattcatg tcttataaag
    15901 aactatcaac aatattaaaa attttatcag atccaagtag gttagaaata ttagatttac
    15961 tttcttgtgg tgagctatgc gcttgtgact tattagaaca ctttcaattc tcacaaccta
    16021 cactaagtca tcatatgaag tcattagtag ataatgaatt agttacaaca cgaaaagatg
    16081 gcaataaaca ttggtatcaa cttaatcatg ctattttaga tgatattatc caaaacttga
    16141 acatcattaa tacatctaat caaagatgtg tatgtaaaaa tgtgaaatca ggtgactgtt
    16201 gatgactatt ttagcaattg taatttttct tttaacttta acctttgtga tttggcaacc
    16261 aaaaggttta gatattggta ttacagcttt aattggagcg gttgttgcta tcattacagg
    16321 agtcgtaagt ctttctgatg tattagaagt aacaggtatt gtttggaatg caactttaac
    16381 ttttgtggct gttattctta tttcattaat attagatgaa attggttttt ttgaatggtc
    16441 tgcgatacat atggtcaagg cttcaaacgg taatggctta aaaatgtttg tttttattat
    16501 gttacttggg gcaattgtag cagcattttt cgcaaatgat ggtgcagctt taatcttaac
    16561 gcctattgta ttagcgatgg taaggaatct aggatttaat caaaaagtga ttttcccctt
    16621 tattattgcc agtggtttta ttgctgatac tacatcactt cccttaattg taagtaactt
    16681 agttaatatc gtttctgcag attacttcga tattggattt attgaatatt ttagccgaat
    16741 gatcattcct aatatattct ctctgattgc tagtattctc gttttatggt tatatttcag
    16801 aaaatccata cctaaaacgt tcgatacaga aaatctatca gatcctaaaa gtgcaattaa
    16861 agattctaag ttatttaagc tttcatggat agtattagca gtactactcg ttggatatct
    16921 tgttagcgag tttatccaaa ttcctgtatc aattattgct ggtattattg cttttatctt
    16981 tgtaatatta gctcgtaaat ctaaagcagt tcatacaaaa caagtgatta aaggtgcacc
    17041 atggaatatc gttgtattct ctattggtat gtatcttgtt gtgtttggac taaaaaatgt
    17101 aggtattaca acggtccttg gggatgtttt aacaaacatt tcaaattatg ggttatttag
    17161 cagcatcatg ggtatgggct ttatagctgc tttcttatct tcgattatga acaacatgcc
    17221 aactgtttta atagatgcaa tagcgattgg ccaatccagt gctacaggaa tattaaaaga
    17281 aggcatggtt tatgcgaatg tcataggttc tgatttagga cctaaaatta cgccaattgg
    17341 ttctttagca acattattgt ggctacatgt cttaacacaa aaaggtgtga agatttcgtg
    17401 gggaacatac tttaaaactg gaattatcat cactattcca gtcctatttg taacactctt
    17461 aggtttatac cttacactaa tcatatttta agaaaagggg ctttaattat ggataagaaa
    17521 acaatttatt ttatatgtac aggaaactct tgtcgtagcc aaatggctga aggttgggga
    17581 aaggaaatat tgggtgaagg ttggaatgtc tattctgctg gtattgaaac acatggtgtt
    17641 aatcctaaag caatagaagc tatgaaagaa gtagatattg atatatcaaa ccatacgtca
    17701 gacttgattg ataatgatat tttaaaacaa tcagatttgg tcgtaacgtt atgtagtgat
    17761 gcagacaata attgtcctat tttaccacca aacgttaaaa aagagcattg gggttttgat
    17821 gatccagcag gtaaagaatg gtcagaattc caacgtgtta gagacgagat taaattagct
    17881 atagaaaagt ttaaattgag ataatcataa acacctctta tttagttaat aagaggtgtt
    17941 ttgccattta aagaacaaaa tttgtgccat atacaatatg ccctctcttt ttctcattaa
    18001 cgaacgttta taacgcaatc atgatgagag tattaataca gttaattatt tgaaatactt
    18061 tagtttacat aatgttgaat tataggtagt gaaattgtat ttattataca ttgtcatatc
    18121 gttgtttaat gatagttaat ttaaggataa tagaattaat attatatata gatgaacaaa
    18181 acaagcaaca gagcaaaaaa acacttttag attattttta ctcattctct attttattta
    18241 tttttgctat aataaataaa gaatattaaa tggagttgtt tttatgaaaa agaaatttgt
    18301 ttctagttgt attgctagta caatcttatt cggcacttta ttaggtgtaa cttataaagc
    18361 tgaagctgca acagtacatg tagctggtgg tgtttggagc catggtattg gaaaacatta
    18421 cgtatggtct tattatagtc acaataaaag aaatcatggt tcaacagcag tagggaaata
    18481 ttcatctttt agtggtgttg ctcgacctgg tgttcaatct aaggcatctg ctccaaaggc
    18541 ttggggtgga aacaaaacat tttatagtct tcactaatta catatattaa ttaaggagaa
    18601 tagacagaat taagtaaact taattctgtc tattctcttg aaagaggcaa tatgaaaaaa
    18661 ttcaaattat ttttagattt tagtacttta ttattaattt cagggctatt atttttattt
    18721 ttcttcaaag aaaatgaaga aattatacct gaaagttcca atattttaac aatctctaat
    18781 tgggataaat ctaacagtaa atcaaaagtg ttagatgtca ttgaatcagg cgccaaaaat
    18841 caaaatatac aaataattaa atccgttaaa gattttgata ataaaaaaga attttttgtt
    18901 ttcaactcaa aacgaaataa ttctgacttt atacgtaata aaacatcact tttaactcca
    18961 tcagatttat taaacagaga gataaaagga aagtattata ttattggtga acatttcaat
    19021 gtagaagagc ttacgagtga attaaaaaaa gctggtttaa catctgaagt tgaatacata
    19081 aatagaaaca tattattttt tgaattagtc atagataatg atttattagt gcctttcata
    19141 ttcttaggcg tattatatct tttgtacttc ttatatgaca gaggatataa tttgaaattt
    19201 tatgctattc aaaagctaca tggcttttca actacacgca ttatttttca taatattcat
    19261 ataaaaatca tttattggct agtacttacc actattttct ttattgctaa tatattaatc
    19321 attcatatag ccaatttaga attggatttc ttaatgttta ttcgtagatt tatcgtgttg
    19381 ctttttgttt ttgcttgtat tactacattg ttgtggctga tttcgtatag tcttcttttg
    19441 aagttaagta ttccattaac cttaaaaggg aaaaaaggat ataagttttc aatatttatg
    19501 ggtaccttca ccaaatgtat catggtgcta atactatctt ttttactggc acaaaattta
    19561 aatgcttata cgaagttaaa gaatatatat gactctgaaa aaatctggca aaagttagat
    19621 aattactata cattagagat ttctcctaat attagaaatt cagaagaaaa acaaatttta
    19681 gaaactaata tatacaattt aattaagaaa agcgaacaac ttggtggatt gcttttaaag
    19741 aataataata tagccaatcc cgataaaaac aattacattc ctgaaaatgg caatgtcttt
    19801 tttatcaata acaattttct gaatttctat aaaaatataa atcatgattt taaaatgatt
    19861 gacaatcatt cggataaaat aaacgtgttt attcctccaa ggttacaata tcaaaaatct
    19921 gaaattcaaa aaaatcacca aggatggatt gactttcaaa agcaacaaaa caaaaaagta
    19981 gatgtgcaag tactgtcaaa aaacgtatct gttttttctt ttgatcgcac aactaatttg
    20041 aaatttggat atctagattc tccaatagta atgttgttga cacctgacga tttaacagga
    20101 gatttttatt tagctgctgt ttctcaaggt ggatatctat ttaaagattt agatacactt
    20161 aaacagttgc ttaaagataa tcacctagaa gaagaaatta gcggtataac taattacaag
    20221 gattctgtgt taaatgaatt aaatgaaacg aaaacaaaaa tgataataac aatagttact
    20281 attattatta acgttttcat tcttttgata gctactgtat ttgaaacaat tcaatatttt
    20341 agctggaata aaaagcaact attattaaga aaaattcatg gttattcatt attcagcagt
    20401 aatgtacgtt atttaacaat ttctatttta ctttctatta tgttagctta cactacgcat
    20461 attttatttg gttcaaagat attactattc ataataatgt ctattgctat tattcaacat
    20521 ttacttcaaa ttgcttatat taaatatctt gaaaaatact ttaaagattt aatgagggag
    20581 atttaaacaa tgaaaagaac tttaattatt gtaacaattg tactattaat catcatactt
    20641 agtctgttat tggttagaaa tgagcattta gatcgtttta acccactgtt aaaagaaaaa
    20701 gtatcttatg ccaaagttcc aaaagatacc caggactata gaaatataac tgtatactct
    20761 aaaaatggag aaaaaaagag ttataaattg gattttttag gttatgatcc tacaaaagaa
    20821 tatgtgaaag taaatcataa agggaaatat gtgcgttcga tagaatacat tacaaaagat
    20881 attcctagct ttttaaaatg aggtgaccga tagtgataaa acttgaaaat gtttttgtaa
    20941 aaaaaggtaa taaaaacatt ttagacggat gtaactttaa ttttgaaaaa ggaaaatcat
    21001 atgctttagt tggagaaagt ggcgctggaa aatctacttt acttaacata atcgctgggt
    21061 tcgaagatgt atcacaagga agcatatata ttgaagataa gttactaaaa aagaaagtcg
    21121 atttttatag atatacgtta gggtatttgt ttcaaaattt tgctttactt gaaaatcaaa
    21181 caatcagtca aaatttagat ttagccctaa agttcaaaaa gaataaaaaa gataatatga
    21241 acttaaagaa agaagtatta aaaaaggtcg gcctagattt agatatcaag agaattgtta
    21301 gttctctaag cggtggtgaa caacaaagag tagcattggc aagattaata ttaaaagatc
    21361 cgaaaatcat tttagctgat gaacctactg gatcactaga tacgaaaaat ggaaaaatag
    21421 ttattgattt attattgaag ctacttgatg aaaataaaac tatgattgtc gtaacgcatg
    21481 atttagagct tgcgaaacga tttgatgtca tagtcaatat ttctgagctt agaagttaag
    21541 aaatattgat aggtatagcc atacatagag aaaaaacaat atgaaatatg attagtcatt
    21601 acttttgagt tttttaattt aaggactgga ttttccagtc cttttttgtg atgacaaaaa
    21661 acaagcctcg cagagcacac gtttttaatg acttatttgg tttttaataa gtctagtatg
    21721 ttaaaacttt tctgtgttta ggtgttataa tcatatgcag tggaagttga tttattatgt
    21781 cttattcaat tattcgagtt gttaaagtga aatcaaaaac aaatacaaga ggtattcaaa
    21841 gagaaaataa aaattatgaa aatatagata ttgatttaag taagtcatat ttaaactatg
    21901 atttagtcaa tgatactaag tttgatttta ataaaaaaat tgatgagaaa atcgaacaaa
    21961 attataaagg gaaacgcaaa attagaacag atgccattaa acatattgat ggattaatta
    22021 catcagataa tgtgttttta atcaattatc tgaagaagag acaaaatagt tttttaagca
    22081 tgctaaagcg ttcttggaag aagaatacgg taaagaaaat cttttatatg cgacagtaca
    22141 tatggatgag ataacaccac atatgcatta tggcgtaatt cctattacta aagatggacg
    22201 tttaagtgcg aaagaagttg taggtaataa aaaagcatta accgaattcc aagatagatt
    22261 caatacgtat attaataagc aaggctatga tttaaaacga ggaatttcta gacaacttac
    22321 aaaagaaaaa catgatcaag ttagcggcta taaacaaaaa acagaatatc ataaacaaat
    22381 gtatatgcgc gagaagcaaa tagaggatca tttaaagtaa gaaaatgata aattgataca
    22441 aaactaccaa aaatcattag atacgcttaa aaagcttctg agtgtcatgt atgaaattaa
    22501 aactaaaaat gtaggtggat ggtttcataa agagaagcaa gaaacaggca atattgtaat
    22561 tactaaaact tattttgaaa aatacactaa acaaattaaa gcagcacaga tgatattaga
    22621 tgattatgaa tggattaaaa gtgggaagtc attaaaaaaa tcagagaaac aaaatgaaag
    22681 tttagttaat gaattgacta gtgtccatat ggaaaatgaa aagctggttg aagaatttaa
    22741 tgatttagca caacgttata attatttgtt gtcagagaat gaaaagaaag ataaagaact
    22801 aaattatacg cttaagttat tcaatcaagt ttttaaaatc attaaaagta tgatgaaaga
    22861 agagcgttat catacgctaa taaatcatat tgataatcat ttagacaatt ctaaaatacg
    22921 tgaagtaatg acgatagata acaatgatga acagttcttt aagaagaaat atcaagcaca
    22981 agaatgagaa atcattttta aagaagatag agaagatggt tatacattat aaaaatagat
    23041 atttaaatgc atttgtttga ggttaattat tttttaggat gaaaaatagg tagcccccct
    23101 ctaacttttt aatatatttt tataaatctt tttaaaaatc ttttaggggc ttgttcagac
    23161 ctagagcaac aagggatttc aatgcctaaa ggagtgtttt tgccacataa aaggagtgtt
    23221 ttaaaaagtt gtactccttt tatggtttga cattgataat aaagtagttt attgtgaata
    23281 aaagttttca aatgggagtg tatattcaaa cgatactcct ttaggttcgt aataaagggg
    23341 ggctgtatca tgacaggaga gacagttgta tataaaaatg aaatgaattt agttccatta
    23401 aggcgattta cagctactga aattaattta ttttttgcga tgtgtaataa attaaaagag
    23461 caagatacta atacattacg tttgtctttt gatgaattaa aaaaattaag taattatagt
    23521 ccagaaacac gtaatattaa tagatttgct aatgatttag ataatgtgta taaaaagatg
    23581 ttgaatttaa ccattagata tgaagatgat gatgtaatag aaagattcgt tttattcaat
    23641 cattatagaa tccataagcg agaacaatat ctagaaatat caacttcttc aaatttaaaa
    23701 cacatattga attcaattac taataatttt acaaaatttg aattaaaaga aatgactagg
    23761 cttaaatcta catattctaa aaatatgttt agattactta aacaatacaa acatacaggc
    23821 tatttaaaaa ttcacatcga tgattttaaa aatcgtttag atatacctaa atcttatcgt
    23881 atgactgata ttaacaaaaa tgtttttaaa cctattatta ttgaattagg ttctatattt
    23941 aataatctta ctatcaataa aatcaaagcg aaaaaagggc gtaaaattga atggatagag
    24001 ttcacatttg acgctgagaa acgcattcat aacaaacgac aacctcaaat gtccaagata
    24061 gataaatcaa gacaatatgt gaggcgtgaa aagacgccta aatggttaga agaacggtca
    24121 tatgaaaagc aacctcaaaa agattacgac ccacaattag agaaagaacg agaggatttt
    24181 ttaaaacaac ttgaactgaa ttgggaataa cgcaactttt cgttgcgagt tggttaacta
    24241 aaagtatcgt gacttttcaa ttattttaat tatagtttga gttaaggagt gattttatga
    24301 aattagctga agctataaaa gaacagagag aattaaaaag atggtctcaa gaggaattag
    24361 ccaatatatt aaaggtttcc agacaaagtg tttctaaatg ggaaagtgcc aaaaactatc
    24421 cttccttaga tattttgatt gctatgagcg atttatttgg aatctcttta gagcatttaa
    24481 ttaaaggaga tgcacgtttt aaaaaagtta ttttagaggg aaattataga gagagtaaca
    24541 gggcaccttc catagttgat tttctttatg atttttggtg gcttttcttt cctgttgccg
    24601 gatttttagt ttgggccatt cattcgttca tgggttgatt ttaaaatcaa aattt
//
