LOCUS       NZ_CP099496            24654 bp    DNA     circular CON 20-MAY-2024
DEFINITION  Staphylococcus aureus strain JL28 plasmid pJL28, complete sequence.
ACCESSION   NZ_CP099496
VERSION     NZ_CP099496.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN15964463
            Assembly: GCF_020702615.2
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 24654)
  AUTHORS   Zou,G., Matuszewska,M., Jia,M., Zhou,J., Ba,X., Duan,J., Zhang,C.,
            Zhao,J., Tao,M., Fan,J., Zhang,X., Jin,W., Cui,T., Zeng,X., Jia,M.,
            Qian,X., Huang,C., Zhuo,W., Yao,Z., Zhang,L., Li,S., Li,L.,
            Huang,Q., Wu,B., Chen,H., Tucker,A.W., Grant,A.J., Holmes,M.A. and
            Zhou,R.
  TITLE     A Survey of Chinese Pig Farms and Human Healthcare Isolates Reveals
            Separate Human and Animal Methicillin-Resistant Staphylococcus
            aureus Populations
  JOURNAL   Adv Sci (Weinh) 9 (4), e2103388 (2022)
   PUBMED   34894204
REFERENCE   2  (bases 1 to 24654)
  AUTHORS   Zhou,R. and Zou,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2022) College of Veterinary Medicine, Huazhong
            Agricultural University, Shizishan Street No.1, Wuhan, Hubei 430070,
            China
REFERENCE   3  (bases 1 to 24654)
  AUTHORS   Zou,G. and Zhou,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2020) College of Veterinary Medicine, Huazhong
            Agricultural University, Shizishan Street No. 1, Wuhan, Hubei
            430070, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.14
            Assembly Name                     :: JL28
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 500.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_020702615.2-RS_2024_05_20
            Annotation Date                   :: 05/20/2024 03:54:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,713
            CDSs (total)                      :: 2,631
            Genes (coding)                    :: 2,549
            CDSs (with protein)               :: 2,549
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 45 of 82
            Pseudo Genes (incomplete)         :: 36 of 82
            Pseudo Genes (internal stop)      :: 25 of 82
            Pseudo Genes (multiple problems)  :: 20 of 82
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP099496.1.
            Bacteria and source DNA available from Huazhong Agricultural
            University.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24654
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="JL28"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pJL28"
                     /geo_loc_name="China:Hubei"
                     /collection_date="2017"
                     /collected_by="Jianli People's Hospital"
     gene            complement(join(24625..24654,1..264))
                     /locus_tag="LPT16_RS13375"
                     /old_locus_tag="LPT16_13375"
     CDS             complement(join(24625..24654,1..264))
                     /locus_tag="LPT16_RS13375"
                     /old_locus_tag="LPT16_13375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            complement(644..1039)
                     /locus_tag="LPT16_RS13380"
                     /old_locus_tag="LPT16_13380"
     CDS             complement(644..1039)
                     /locus_tag="LPT16_RS13380"
                     /old_locus_tag="LPT16_13380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent arsenate reductase"
                     /protein_id="WP_000358995.1"
                     /translation="MDKKTIYFICTGNSCRSQMAEGWGKEILGEGWNVYSAGIETHGVN
                     PKAIEAMKEVDIDISNHTSDLIDNDILKQSDLVVTLCSDADNNCPILPPNVKKEHWGFD
                     DPAGKEWSEFQRVRDEIKLAIEKFKLR"
                     /name="thioredoxin-dependent arsenate reductase"
     gene            complement(1057..2349)
                     /gene="arsB"
                     /locus_tag="LPT16_RS13385"
                     /old_locus_tag="LPT16_13385"
     ARG             complement(1061..2346)
                     /name="arsB"
                     /gene="arsB"
                     /gene_name="arsenite efflux transporter membrane subunit
                     ArsB"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="99.77"
                     /coverage="100.0"
     gene            complement(2346..2660)
                     /gene="arsR"
                     /locus_tag="LPT16_RS13390"
                     /old_locus_tag="LPT16_13390"
     ARG             complement(2350..2660)
                     /name="arsR"
                     /gene="arsR"
                     /gene_name="As(III)-sensing metalloregulatory
                     transcriptional repressor ArsR"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="99.04"
                     /coverage="100.0"
     gene            complement(2721..3479)
                     /locus_tag="LPT16_RS13395"
                     /old_locus_tag="LPT16_13395"
     CDS             complement(2721..3479)
                     /locus_tag="LPT16_RS13395"
                     /old_locus_tag="LPT16_13395"
                     /inference="COORDINATES: protein motif:HMM:NF012464.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000164959.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYTAPAEKQSGKSIENRPVFQEVLN
                     FLRMGDRLIVESIDRLGRNYEEIIQTVNYLKDKEVQLMITSLPMMNEVIGNPLLDKFMK
                     DLIIQILAMISEQERNESKRRQAQGIQVAKEKGIYKGRPVLYSPNAKDPQKRLVYYRVV
                     ELLEQGKSISTIAKEVGITRQTIYRIKNSK"
                     /name="recombinase family protein"
     gene            complement(3472..4914)
                     /locus_tag="LPT16_RS13400"
                     /old_locus_tag="LPT16_13400"
     CDS             complement(3472..4914)
                     /locus_tag="LPT16_RS13400"
                     /old_locus_tag="LPT16_13400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /protein_id="WP_000790712.1"
                     /translation="MKNKEKYLTNFSEAKRKKATQKYNIIKPFILGEQSLSSISKSKGI
                     ALSTLYRWNKSYKEQGLKGLIYATKADKGTRKIEPKIIDEIERLALMNKRNSIATIHRK
                     TTNYCKENNFDIPSYKQIYSVIKAMPKSVIDFSHQGEKYYQNKYDLIQIRESSRPNEIW
                     QADHTLLDIFILDQKGNINRPWLTIIMDDYSRAIAGYFLSFDAPNAQNTALTLHQAIWN
                     KNDTNWPVCGIPEKFYTDHGSDFTSHHMEQVAIDLKINLMFSKVGVPRGRGKIERFFQT
                     VNQTFLEQLPGYINNNDTPSNLINFHNFEEKLRYFLIEDYNQKEHSTIHTTPISRWNSN
                     HFFPNMPSSLEQLDLLLLEIPKSRKVHSDGIHFQGFRYSNTNLAAYVGEYVLIRYNPND
                     MAEIRVFYRDEFLCTAICPEIADYSIDIKDIQHARSQRRKHLKQNIASPSTTELIKEEK
                     NCGYSPQETTKNVKKLKRYRND"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            complement(4886..5479)
                     /locus_tag="LPT16_RS13405"
                     /old_locus_tag="LPT16_13405"
     CDS             complement(4886..5479)
                     /locus_tag="LPT16_RS13405"
                     /old_locus_tag="LPT16_13405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(5743..6123)
                     /gene="blaI"
                     /locus_tag="LPT16_RS13410"
                     /old_locus_tag="LPT16_13410"
     ARG             complement(5747..6123)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            complement(6113..7870)
                     /gene="blaR1"
                     /locus_tag="LPT16_RS13415"
                     /old_locus_tag="LPT16_13415"
     ARG             complement(6117..7870)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            7977..8822
                     /gene="blaZ"
                     /locus_tag="LPT16_RS13420"
                     /old_locus_tag="LPT16_13420"
     ARG             7978..8819
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(9348..9767)
                     /locus_tag="LPT16_RS13425"
                     /old_locus_tag="LPT16_13425"
     CDS             complement(9348..9767)
                     /locus_tag="LPT16_RS13425"
                     /old_locus_tag="LPT16_13425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            9891..10862
                     /locus_tag="LPT16_RS13430"
                     /old_locus_tag="LPT16_13430"
     CDS             9891..10862
                     /locus_tag="LPT16_RS13430"
                     /old_locus_tag="LPT16_13430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            complement(11034..11126)
                     /locus_tag="LPT16_RS13435"
                     /old_locus_tag="LPT16_13435"
     CDS             complement(11034..11126)
                     /locus_tag="LPT16_RS13435"
                     /old_locus_tag="LPT16_13435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(11283..11630)
                     /locus_tag="LPT16_RS13440"
                     /old_locus_tag="LPT16_13440"
     CDS             complement(11283..11630)
                     /locus_tag="LPT16_RS13440"
                     /old_locus_tag="LPT16_13440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_096002315.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEVF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(11649..12266)
                     /gene="cadD"
                     /locus_tag="LPT16_RS13445"
                     /old_locus_tag="LPT16_13445"
     ARG             complement(11653..12266)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(13383..13577)
                     /locus_tag="LPT16_RS13450"
                     /old_locus_tag="LPT16_13450"
     CDS             complement(13383..13577)
                     /locus_tag="LPT16_RS13450"
                     /old_locus_tag="LPT16_13450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            13687..14379
                     /locus_tag="LPT16_RS13455"
                     /old_locus_tag="LPT16_13455"
     CDS             13687..14379
                     /locus_tag="LPT16_RS13455"
                     /old_locus_tag="LPT16_13455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            complement(14547..14696)
                     /locus_tag="LPT16_RS13460"
                     /old_locus_tag="LPT16_13460"
     CDS             complement(14547..14696)
                     /locus_tag="LPT16_RS13460"
                     /old_locus_tag="LPT16_13460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(15243..>15532)
                     /locus_tag="LPT16_RS13465"
                     /old_locus_tag="LPT16_13465"
                     /pseudo=""
     CDS             complement(15243..>15532)
                     /locus_tag="LPT16_RS13465"
                     /old_locus_tag="LPT16_13465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(15552..16535)
                     /locus_tag="LPT16_RS13470"
                     /old_locus_tag="LPT16_13470"
     CDS             complement(15552..16535)
                     /locus_tag="LPT16_RS13470"
                     /old_locus_tag="LPT16_13470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            16961..17704
                     /locus_tag="LPT16_RS13475"
                     /old_locus_tag="LPT16_13475"
     CDS             16961..17704
                     /locus_tag="LPT16_RS13475"
                     /old_locus_tag="LPT16_13475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(17920..18105)
                     /locus_tag="LPT16_RS13480"
                     /old_locus_tag="LPT16_13480"
     CDS             complement(17920..18105)
                     /locus_tag="LPT16_RS13480"
                     /old_locus_tag="LPT16_13480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466617.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSAWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            18254..18349
                     /locus_tag="LPT16_RS13485"
                     /old_locus_tag="LPT16_13485"
     CDS             18254..18349
                     /locus_tag="LPT16_RS13485"
                     /old_locus_tag="LPT16_13485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001002795.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGYWLHKRDKK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(18564..18905)
                     /locus_tag="LPT16_RS13490"
                     /old_locus_tag="LPT16_13490"
     CDS             complement(18564..18905)
                     /locus_tag="LPT16_RS13490"
                     /old_locus_tag="LPT16_13490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761344.1"
                     /translation="MKLAEAIKEQRELKRWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRAPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(18992..19852)
                     /locus_tag="LPT16_RS13495"
                     /old_locus_tag="LPT16_13495"
     CDS             complement(18992..19852)
                     /locus_tag="LPT16_RS13495"
                     /old_locus_tag="LPT16_13495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            complement(20215..20715)
                     /locus_tag="LPT16_RS13500"
                     /old_locus_tag="LPT16_13500"
     CDS             complement(20215..20715)
                     /locus_tag="LPT16_RS13500"
                     /old_locus_tag="LPT16_13500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273007.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTYFEKYTKQIKAAQMILD
                     DYEWIKSGKSLKKSEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQE"
                     /name="hypothetical protein"
     gene            complement(20782..21108)
                     /locus_tag="LPT16_RS13505"
                     /old_locus_tag="LPT16_13505"
     CDS             complement(20782..21108)
                     /locus_tag="LPT16_RS13505"
                     /old_locus_tag="LPT16_13505"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="WP_001582045.1"
                     /translation="MEEEYGKENLLYATVHMDEITPHMHYGVIPITKDGRLSAKEVVGN
                     KKALTEFQDRFNTYINKQGYDLKRGISRQLTKEKHDQVSGYKQKTEYHKQMYMREKQIE
                     DHLK"
                     /name="plasmid recombination protein"
     gene            complement(21048..21425)
                     /locus_tag="LPT16_RS13510"
                     /old_locus_tag="LPT16_13510"
     CDS             complement(21048..21425)
                     /locus_tag="LPT16_RS13510"
                     /old_locus_tag="LPT16_13510"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="WP_001582042.1"
                     /translation="MSYSIIRVVKVKSKTNTRGIQRENKNYENIDIDLSKSYLNYDLVN
                     DTKFDFNKKIDEKIEQNYKGKRKIRTDAIKHIDGLITSDNVFLINYLKKRQNSFLSMLK
                     RSWKKNTVKKIFYMRQYIWMR"
                     /name="plasmid recombination protein"
     gene            complement(21663..22289)
                     /locus_tag="LPT16_RS13515"
                     /old_locus_tag="LPT16_13515"
     CDS             complement(21663..22289)
                     /locus_tag="LPT16_RS13515"
                     /old_locus_tag="LPT16_13515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(22301..22612)
                     /locus_tag="LPT16_RS13520"
                     /old_locus_tag="LPT16_13520"
     CDS             complement(22301..22612)
                     /locus_tag="LPT16_RS13520"
                     /old_locus_tag="LPT16_13520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            complement(22616..24550)
                     /locus_tag="LPT16_RS13525"
                     /old_locus_tag="LPT16_13525"
     CDS             complement(22616..24550)
                     /locus_tag="LPT16_RS13525"
                     /old_locus_tag="LPT16_13525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713731.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTTIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLTLKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTPDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     ARG             complement(648..1039)
                     /name="arsC"
                     /gene="arsC"
                     /gene_name="thioredoxin-dependent arsenate reductase"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             7978..8822
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="97.15"
                     /coverage="100.0"
     BGC             1..5264
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(15040..15187)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(15246..15421)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.697"
                     /coverage="94.0"
                     /evalue="1.04e-65"
     Typing          complement(15553..16535)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          16962..17704
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(18993..19852)
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(21052..21425)
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.2"
                     /coverage="100.0"
                     /evalue="1.03e-73"
ORIGIN
        1 accccaagcc tttggagcag atgccttaga ttgaacacca ggtcgagcaa caccactaaa
       61 agatgaatat ttccctactg ctgttgaacc atgatttctt ttattgtgac tataataaga
      121 ccatacgtaa tgttttccaa taccatggct ccaaacacca ccagctacat gtactgttgc
      181 agcttcagct ttataagtta cacctaataa agtgccgaat aagattgtac tagcaataca
      241 actagaaaca aatttctttt tcataaaaac aactccattt aatattcttt atttattata
      301 gcaaaaataa ataaaataga gaatgagtaa aaataatcta aaagtgtttt tttgctctgt
      361 tgcttgtttt gttcatctat atataatatt aattctatta tccttaaatt aactatcatt
      421 aaacaacgat atgacaatgt ataataaata caatttcact acctataatt caacattatg
      481 taaactaaag tatttcaaat aattaactgt attaatactc tcatcatgat tgcgttataa
      541 acgttcgtta atgagaaaaa gagagggcat attgtatatg gcacaaattt tgttctttaa
      601 atggcaaaac acctcttatt aactaaataa gaggtgttta tgattatctc aatttaaact
      661 tttctatagc taatttaatc tcgtctctaa cacgttggaa ttctgaccat tctttacctg
      721 ctggatcatc aaaaccccaa tgctcttttt taacgtttgg tggtaaaata ggacaattat
      781 tgtctgcatc actacataac gttacgacca aatctgattg ttttaaaata tcattatcaa
      841 tcaagtctga cgtatggttt gatatatcaa tatctacttc tttcatagct tctattgctt
      901 taggattaac accatgtgtt tcaataccag cagaatagac attccaacct tcacccaata
      961 tttcctttcc ccaaccttca gccatttggc tacgacaaga gtttcctgta catataaaat
     1021 aaattgtttt cttatccata attaaagccc cttttcttaa aatatgatta gtgtaaggta
     1081 taaacctaag agtgttacaa ataggactgg aatagtgatg ataattccag ttttaaagta
     1141 tgttccccac gaaatcttca cacctttttg tgttaagaca tgtagccaca ataatgttgc
     1201 taaagaacca attggcgtaa ttttaggtcc taaatcagaa cctatgacat tcgcataaac
     1261 catgccttct tttaatattc ctgtagcact ggattggcca atcgctattg catctattaa
     1321 aacagttggc atgttgttca taatcgaaga taagaaagca gctataaagc ccatacccat
     1381 gatgctgcta aataacccat aatttgaaat gtttgttaaa acatccccaa ggaccgttgt
     1441 aatacctaca ttttttagtc caaacacaac aagatacata ccaatagaga atacaacgat
     1501 attccatggt gcacctttaa tcacttgttt tgtatgaact gctttagatt tacgagctaa
     1561 tattacaaag ataaaagcaa taataccagc aataattgat acaggaattt ggataaactc
     1621 gctaacaaga tatccaacga gtagtactgc taatactatc catgaaagct taaataactt
     1681 agaatcttta attgcacttt taggatctga tagattttct gtatcgaacg ttttaggtat
     1741 ggattttctg aaatataacc ataaaacgag aatactagca atcagagaga atatattagg
     1801 aatgatcatt cggctaaaat attcaataaa tccaatatcg aagtaatctg cagaaacgat
     1861 attaactaag ttacttacaa ttaagggaag tgatgtagta tcagcaataa aaccactggc
     1921 aataataaag gggaaaatca ctttttgatt aaatcctaga ttccttacca tcgctaatac
     1981 aataggcgtt aagattaaag ctgcaccatc atttgcgaaa aatgctgcta caattgcccc
     2041 aagtaacata ataaaaacaa acatttttaa gccattaccg tttgaagcct tgaccatatg
     2101 tatcgcagac cattcaaaaa aaccaatttc atctaatatt aatgaaataa gaataacagc
     2161 cacaaaagtt aaagttgcat tccaaacaat acctgttact tctaatacat cagaaagact
     2221 tacgactcct gtaatgatag caacaaccgc tccaattaaa gctgtaatac caatatctaa
     2281 accttttggt tgccaaatca caaaggttaa agttaaaaga aaaattacaa ttgctaaaat
     2341 agtcatcaac agtcacctga tttcacattt ttacatacac atctttgatt agatgtatta
     2401 atgatgttca agttttggat aatatcatct aaaatagcat gattaagttg ataccaatgt
     2461 ttattgccat cttttcgtgt tgtaactaat tcattatcta ctaatgactt catatgatga
     2521 cttagtgtag gttgtgagaa ttgaaagtgt tctaataagt cacaagcgca tagctcacca
     2581 caagaaagta aatctaatat ttctaaccta cttggatctg ataaaatttt taatattgtt
     2641 gatagttctt tataagacat gaataaacct cctagatatt aaatagatta acatctatat
     2701 agattattgt ctatgttact ttatttacta ttttttattc tatatatagt ttgacgtgta
     2761 ataccaactt ctttagctat agtacttata gatttaccct gttcaagtaa ttcaacaact
     2821 cggtaataaa ctaaacgctt ttgtgggtct ttagcattgg gagaatacag aacaggtctc
     2881 cctttatata tacctttttc tttggcgact tgaatccctt gagcttgtcg acgtttactt
     2941 tcatttcttt cttgttctga aatcattgct aaaatttgaa taattaaatc tttcataaat
     3001 ttatctagta gtggatttcc aatgacttca ttcatcatag gtaaactcgt tatcatgagc
     3061 tgaacttctt tatcttttaa gtaattaact gtttgaatta tttcctcgta atttcttcct
     3121 agtctatcaa tagattcaac aattaaacga tctcccattc ttaaaaaatt taatacttct
     3181 tgaaaaacag gtctgttttc tatagattta cctgattgtt tttctgctgg tgcagtataa
     3241 aatattttat ccaccgatag tatgtcatcg gtcgttttac tagctaaatc ttcccaacct
     3301 ctatggttaa cttgtttttc aatagtatcc caatttgtgt aatacctaga cgataaagtt
     3361 tttccgacac caggttgacc ataacatata ccaatatact gatatttaat acaagcatca
     3421 caaaattcag caaagcgttt atactctttc gtttcaatga aattttgatt tttagtcatt
     3481 acgatacctc tttaattttt tgacgttttt agtcgtttct tgaggtgaat aaccacaatt
     3541 tttttcttcc ttaattaatt ccgtggtact tggactagca atattttgtt ttaagtgttt
     3601 tcttctctga ctacgagcgt gctgtatgtc ttttatatct atggagtaat cagctatttc
     3661 tggacatata gcagtacaaa gaaattcatc tctataaaac acacgtattt cagccatatc
     3721 atttgggtta taacgaatca gtacatattc acctacataa gctgctagat tagtattact
     3781 gtatcgaaaa ccttgaaaat gaatgccatc tgaatgaact tttctagatt taggtatttc
     3841 caacaataat aaatcaagtt gttctaagct actcggcata ttagggaaaa agtgattact
     3901 attccaacga ctgataggcg tggtatgaat agtactatgt tctttttgat tataatcttc
     3961 aattaaaaag taacgtaatt tttcttcaaa attgtgaaaa tttattagat tactaggagt
     4021 atcattattg tttatatatc caggcagttg ttctaagaaa gtttgattaa ctgtctgaaa
     4081 gaatcgttct atttttccac gaccacgagg aacaccaact ttcgaaaaca tcaagttaat
     4141 tttcaaatca atagcgactt gttccatatg atgtgaagta aagtcacttc catgatctgt
     4201 gtagaatttt tcgggtatac cacacactgg ccaattggta tcatttttat tccatattgc
     4261 ttggtgtagt gttaatgctg tgttttgagc attgggggca tcaaaactta agaaatagcc
     4321 tgcaattgca cgactatagt catccataat aatagttagc catggtctat tgatattacc
     4381 tttttggtct aatataaaga tatctagcaa agtatggtct gcttgccata tttcattggg
     4441 tctcgaggat tctctaattt gtattaaatc gtacttattt tgatagtatt tttcaccctg
     4501 atgagagaaa tcaataacag acttaggcat cgctttaata acactataaa tttgtttata
     4561 acttggtata tcaaaattat tttctttaca gtaattagtg gttttcctat gaattgtggc
     4621 tatactattt cttttattca taagcgcaag gcgttcaatt tcatcaatta tctttggttc
     4681 tattttacgt gttcctttat cagcttttgt cgcatagatt agtcctttaa gtccttgttc
     4741 tttatatgac ttattccatc tataaagggt gcttaacgca atccctttac ttttagaaat
     4801 acttgataaa gattgttcgc ctaggataaa aggttttata atattgtact tttgagtagc
     4861 ttttttacgt ttggcttcag aaaaattagt tagatacttc tccttgtttt tcatcttcct
     4921 tgtcctccaa tttattgagg taacgataaa ttgttgtacg tgaaacatgc cactgttctg
     4981 caattgtctt aattggcgtg ccattatcat aaagtgtctt aagtaagttt aaatcttttt
     5041 gatttaattt ttctggtctg cctccatatc ggcctctagc acgtgctgca attcggccag
     5101 ctgaagaacg ctctaaaatt aaattacgtt caaattctgc aaatgctgcg aataaatgaa
     5161 ataataattg tccagttgaa cttgatttat ccattgttat attttcttct aaactatgga
     5221 aacttacacc tcgttcgtta agctcattaa ctaatgtgat taaatcctcc atattacgtc
     5281 ccaatctatc taatctccaa acaacaatcg tatctcctga cctcgcaaat tcaattgctt
     5341 tatctaaacc aggtctttta ctttttgaac cactcatatg gtcattaaat atcttttcac
     5401 aaccatatgt atttaatcga tcctcctgta aatttaaatt ttgtaatcca gttgaaactc
     5461 ttgcataacc tattttcaaa atacaaacct cctatataca tcttcagtgt accataactt
     5521 aattacaagg ccttttatga acatagattt tttgttgggt ttttgaacac ataatcctat
     5581 gtaattctta cttatttaga cataaaagaa gagtgtccag aaaatggtta ttttctggac
     5641 actctcatct ttaataatat attttaaatg tcattaacaa aactaattta ataagagtca
     5701 agtatggttt acatatgtat tatgtttgaa acatacctct aattactttt tactaatatc
     5761 atttaaaatg tctcgcaatt cttcaatttc tttgttattt aattcttcat ttttcgcaaa
     5821 attcagcact aaacttttca tatcccctcc atacagttta ttaagaaagg ttttagcagt
     5881 tttcatttta atatcgtctt ctttaatatt tgatgagtaa aaataaatat tttctgattt
     5941 gtatcgtttt ataatctctt ttttatatag tcttgtgatt aatgttctaa tcgttttatc
     6001 actaacttct ttatattttt gaatttcaac tacaatttca ttagctgata ctgatttttt
     6061 atcccatatt atattcataa catcccattc agccatagat atttcaactt gcttattggt
     6121 catttaaaac acccattcct tttaatattt tttcacttat taattcagca tttttcccag
     6181 acgggtttcc atctgataaa tgtgtagcaa aataatactt atcatgattt gtaattacgt
     6241 aacctacaaa ccacccatta ttatacttcc cgtttactat acctgtacct gttttcccat
     6301 acagttcata cttttcattt ttcttaatca ataatgaaga agataattga ttctttgctt
     6361 ttttactaaa atggttattt tgttccatca tatttttaaa aactattact tgttcaagat
     6421 tagatatttt caaactatct tccatccaat agcttttata acttcccaaa ttttcattac
     6481 cataatttaa ttgcttgagt tgagccgcag tatagttctt tggtatttga ttactaatac
     6541 gttcgaagta ccaattaact gaattttgca ttgctgtatt taaatcttgt tccttattcc
     6601 aagactcgaa aagataatgt ttatgattcc atgacatacg tgaattttta tcacttataa
     6661 tatgacggtc aagtccaaac agtgctaaat aaattttgta agttgaatca ggagaatatc
     6721 tttttctact ttctttttca ttataaatat agtatttgtc tttcttcatg ctgtacataa
     6781 cgaaagatcc actatttgaa ccaaaatttt tactttcatc taaaatttgg taatcgcttt
     6841 gtaagggctt tttataatta taatcagtta aggattgccc cattaaaaac tggctttgaa
     6901 ttatcatgat aaaaaaagta aaaatacaaa taaaaattag aattaatttt gactgctttt
     6961 tcagatcggc ttcttttata ttaattaatc tacttttgag taatgatttt ttaccattaa
     7021 atgaatggct taatatattt ttgttggaaa atggggtttt taatacggag tccataatag
     7081 attccgcata agttttaaat tcatttttgt taatattatt aaggacaaat ctatcggctt
     7141 ctacttcatt gtcatgaatt atctttcttt ttacaatatg tactaatgga ttgtaactca
     7201 taataataga gaagatatta aagataatta aatgtaaagt atctctattt ttagcatgag
     7261 catattcatg cagtattata tattttagtc ttttatcaat tacactttta aaatatgaac
     7321 taggaatcaa aataatatat ttcccatacc aaaaagttat tggagattga atagcctctg
     7381 cttttcgaat cacaatattt tttttatatt gatggttgaa aagtatcgta tctattttat
     7441 ttttttcatt ttcgtttaga taaagtgact gtttctttaa atatttaaga tataataagg
     7501 ctttcaaaaa tttaaaactt aaaataataa ctaaaactat ccaaataact gtgcagatat
     7561 tatcaattga atcccaatta aacttatgga tatctgttgt gaactcttga ataggtttgg
     7621 tggtatttat gttatggttc aaatcgtgtg acttactttc aactgtgggc gcttgattat
     7681 tcacattatt aaattttata aaagagaatt taattgggat aaaaggaatt aatccagcaa
     7741 gcatagttag ataccaaact ttataattta aactataatt aaaatagcgt tttaatatgt
     7801 acctaaaaaa tactaacaat agaaatataa aacaaaagct tactacgctc attattagta
     7861 atttagccat tttgacacct tctttcaaat atttataata aacaattgac atcaatatta
     7921 caattgtaat attattgatt tataaaaatt acaactgtaa tatcggaggg tttattttga
     7981 aaaagttaat atttttaatt gtaattgctt tagttttaag tgcatgtaat tcaaacagtt
     8041 cacatgccaa agagttaaat gatttagaaa aaaaatataa tgctcatatt ggtgtttatg
     8101 ctttagatac taaaagtggt aaggaagtaa aatttaattc agataagaga tttgcctatg
     8161 cttcgacttc aaaagcgata aatagtgcta ttttgttaga acaagtacct tataataagt
     8221 taaataaaaa agtacatatt aacaaagatg atatagttgc ttattctcct attttagaaa
     8281 aatatgtagg aaaagatatc actttaaaag aacttattga ggcttcaatg acatatagtg
     8341 ataatacagc aaacaataaa attataaaag aaatcggtgg aatcaaaaaa gttaaacaac
     8401 gtctaaaaga actaggagat aaagtaacaa atccagttag atatgagata gaattaaatt
     8461 actattcacc aaagagcaaa aaagatactt caacgcctgc tgctttcggc aagactttaa
     8521 ataaacttat cgcaaatgga aaattaagca aaaaaaataa aaatttctta cttgatttaa
     8581 tgtttaataa taaaaacgga gacactttaa ttaaagatgg tgttccaaaa gactataagg
     8641 ttgctgataa aagtggtcaa gcaataacat atgcttctag aaatgatgtt gcttttgttt
     8701 atcctaaggg ccaatctgaa cctattgttt tagtcatttt tacgaataaa gacaataaaa
     8761 gtgataagcc aaatgataag ttgataagtg aaaccgccaa gagtgtaatg aaggaatttt
     8821 aatattctaa atgcataata aatactgata acatcttata gtttgtatta tattttgtat
     8881 tatcgttgac atgtataatt ttgatatcaa aaactgattt tccctttatt attttcgaga
     8941 tttattttct taattctctt taacaaacta gaaatattgt atatacaaaa aatcataaat
     9001 aatagatgaa tagtttaatt ataggtgttc atcaatcgaa aaagcaacgt atcttattta
     9061 aagtgcgttg cttttttctc atttataagg ttaaataatt ctcatatatc aagcaaagtg
     9121 acaatagcat tttaaaagta ttttttattg ttcgattagg gtaaacctaa ataatacata
     9181 aattatatta caatatgttt attatagagg ctaaagtatc ttagaaattt ggatagtagg
     9241 tttttcggga ataaaagtat agttggcttt aatatataat taagctaagc tatcatttat
     9301 atttactcga ttataattcg cacttcaact ttttaataac gtaaaaatta aaacgtagtt
     9361 ttatttatct ttagtaatat ctttttaaac actacagttt cttcattagt taaattagcg
     9421 aagtaatgat tattaagttg ataggctttc ttttctaatg ttggccataa gtcttttgct
     9481 ttatttgtac tgtttattag cacagttctt ctattttcat tatcagtttg acgtgttatt
     9541 agatcctttt tggacatctt atctaatatt ccagatattg ttgaaggttc taaatttaaa
     9601 gtattaccaa tcgctttagg tgtattcaaa ttactattaa tcaagcaatt caaaacacca
     9661 tattctgctg gagtaatatt atagggactt aataaacttt taaaatgttt aaaaactcta
     9721 ttctgagaag tactcaacaa ataatttata caattatcta attccacaac taaaacctct
     9781 cttaaatcat tagtattgac tcgcttatca tatcatgata agttttgtag gaaaatagtt
     9841 ttgcaacaaa aacatacttc tacaaaacaa ttgtgaaaga aggctaataa atgttcaatg
     9901 cggtagtagt gagaaaaagt gcatcaaatg ttagttataa agtagaaaaa gttgatgaat
     9961 ctcatttatc gaagggtgat gtattagtaa aagtggtata ctcttcaata aattataagg
    10021 atatgctagc tttacaatat aaaggcggtg taattagaga ttatcctatg attcctggta
    10081 tagattttgc aggtattgtt gaatcaagtt cgaatgataa gtttaaagaa ggcgataatg
    10141 tattagttac tggttatgat gttggcgtga cacatacagg tggattttca gaatatgcac
    10201 aagtgcctgg agagtggatt gttcctattc cccaagaaat gtctattaaa gagtctatgg
    10261 tatatggcac agccggtttt acggcagcat tatcaatttt tgaactagaa aaatatggaa
    10321 tgaatatcaa atcacaacct gaaattttag tgtctggggc tacaggtggt gtgggcagtg
    10381 ttgctataca aattttacat aaaattggat atgaaaatat cactgctatc gtaagaaaag
    10441 aaaagcaaat agaaatcgca aaaaaattag gtgcaaaaca agtaataata attgaagatg
    10501 ataataaacc gcttaaaaaa ggtatttttg attatttctt agatacagtg gggagtaatg
    10561 taacattata cggtttaaaa cgtctaaatt atcaaggtgt tgctactgta tgtggaaatg
    10621 tagcaggaaa ttcacttaac gctaatatat taccgtttat tcttagaggt attaaattaa
    10681 ttggcattga ttctgtatat gttgatcata atatccgtga agatatatgg agtaagttag
    10741 caaatgaatg gaatatagga aattcacttc tatacaatga aattggattt gaagaattct
    10801 ataaaacgat agatcagctt ttaaaaggac aacatttagg aagaactatt ttaaaagtat
    10861 aagtgtgagt attcattaat acatttacta ttaattcaat cattttgcat ttctctacta
    10921 accagtgtta taatttatat aacgaaaatg attaacaatt aatgcaccaa tccccacact
    10981 attgcagtag tgtggggatt ttttcgatgc tggcttataa agtcgcctat taattatttg
    11041 ttgcgtttac taagccaata agtataatac gcaacagcac agccactgat gactggtgct
    11101 atgatgtgaa cgaaaatgat tagcaaagta atgcacctcc tctcttcgtc aattgacgcc
    11161 tgagagatag gcgactctat tattatacca tctgtgaata tacaagcata tctacttccg
    11221 ataagtcgtc ttatgttata taactttgtt ttttatagta tcaagacaag aagaaactcg
    11281 tttcaaaaaa cctcatgatt tttagagaaa aactctctta tttcatcgtc tttaataaaa
    11341 taatatgcca tctttccatc tttataaaaa tcaagtacct catttttata taaaagcctt
    11401 aaatgatgtg aagttgaagc aacactcatt ttcaatatca aagaaatatc acaaacacac
    11461 aactcatctt ctttaatcaa agataatatg attttcaatt tcttctcatc acaaattttt
    11521 tctaaaatgt taagtaattt cttagattta tcatcttcta aaaaacttaa agcattgtta
    11581 actttatcct catgtacaca gatcacatca caagtatttt cataactcat ataaaatcac
    11641 accctaaatt aaaatataaa tcctaaaatt gtttgaatag tgtcattttc aataataata
    11701 aataaaccta aagctatata aataatagcc ataatccaac gactaaattt ctcaacaatt
    11761 tctccaattc ctggaatatt agctaatttt tgtgcagtaa acaccaagaa gaaaattaaa
    11821 attaaaaaga caaacagagt aagtaataaa ttagtaacac ttaatgtcac aaaatatgga
    11881 acaaataaac caatattatc ggcgccacaa cttgctatcg taacaattgc aaccgtacca
    11941 actaatttag acaatccttt ttcattcaat tcttttttag ctctcttttc tccttcacaa
    12001 tcatcataaa tagccacttt aattccaaga taaattggta ttaaacccaa taaacctaat
    12061 atccactttt ctggaacata atttaataca aaagctaaaa acaaactaac taatattaaa
    12121 ataatagacc ctaaatattg accaacataa atatctctat attcttttct agtctttgct
    12181 ctagcaaaaa atattaataa aattactaat aaatcaactg ctgtagcaat ataaagaaca
    12241 gcagcagcaa caaccgtttg aatcataata cacctcattc aaaaatattt ttgaatgtat
    12301 tataacttat atttttaaat aatcataggt gctttattcc aattgcttta ttgacgttga
    12361 gcctcggaac ccttaacaat cccaaaactt gtcgaatggt cggcttaata gctcacgcta
    12421 tgccgacatt cgtctgcaag tttagttaag ggttcttctc aacgcacaat aaattttctc
    12481 ggcataaatg cgtgtctatg cgtagacatg gagacacttc agaattatgg agtgattaca
    12541 tgagtttaac tatttttctt tattcagttt taggaagttt attagcaaat tatatctacg
    12601 aaaaatcttc aaaataaata actttttcgg ttctactttg tacactttat ctacctggta
    12661 gacctaattg ttattgcttt acaggtctaa aattcgtcgt tataatctag ttaaatcccg
    12721 taagggcgca cttatacgtc ggataaatcg acatgtgcaa aaacgtaatc gaccttcgtc
    12781 gattttttta tttcaaaatt aaagaaacgg cttgagatat tccgagcagt tataaaaatt
    12841 aatttgcgtt gaatattgct actacattct tgaaaaagtg atgtagattt atagcccata
    12901 acttttttga attacatcga cgatacggcg tcgaaagaaa aataaataga ccgtatgaaa
    12961 gaaaaagcta cctcacttta tctggggtag cttttatttt ttatgccctt attttgaatt
    13021 ttaagagggc attttaaaga tttaggggtg attcatatag ttttatatct aaaacttata
    13081 tatgctttta aaacgcaaat atgagccaaa taaatatatg ctattttcaa aaacaaaaat
    13141 ttgagcaaaa acaataacta tttttagaca ctgcccattt acatgcaaat taaaaattag
    13201 cataaaattc tttaaaactt ccccacgttt ttctaaattc ctgtagggcg tttttatcaa
    13261 aaatcaagac aagaagaaac tcgttcacac tcgtttcaaa aaaacaagaa atctaatcta
    13321 tacacctacc gttttccaac cccctcaaag catacaaatt aaaaacaaaa ttattcataa
    13381 tcttactttc ttttaacaaa aacataaaaa ccataaatag acaaattaac tatcaaaggc
    13441 aataaacagt ataaaaaaac cacgaataaa tcttcatcaa catctaaaat aaaaaagaat
    13501 aaaacaatta acaaaatact aattaacaaa cctaaaagtg gcaaactttt tatatatttt
    13561 tctaaatttt cattcataaa atagactcct ttcaaaaata tgtttataaa tatattaaaa
    13621 taaatattga ttttataaag cgcttactta tacaattaaa atatcttatt atcttggagg
    13681 tatcaaatga aaattataaa attattttca ataatttcct tgttcctact ggtatttagc
    13741 gcgaattttt ctaatgctta cgcaaatgaa gaacaaaaaa gttctttact agaaaatcaa
    13801 aaagaaaaat tgaaaagcaa aaacatcgaa gtatcacaaa tgaccaagaa agaaataagt
    13861 tttctagaac aattgcaaaa taaaaatgaa gatatgcaaa aattcgaaaa gcaaatgaaa
    13921 aaagaaggat ttaaaaaaat aaagctagaa gacaaaaatt ctaaattaaa atatctagct
    13981 acagaagcaa atgataaaaa tgcatatggc tacatagcta ataacgctta taaaaatgaa
    14041 aaaacaaaag aaattgtagt ttctgaaaca atatatgata actacaacaa aaaaatcaca
    14101 aaattcattg ccgaaaaaag aagtatgact gaaaacaaag agggaaaaat acttattaac
    14161 aaaaattacg ttgaatataa ggctgaaaaa gttgataaaa acagaccggt aacatatgca
    14221 ggattcaaat ggaacggcaa agcattcgct tgtagtatgg ctggacttta tgcatgtgct
    14281 cactactgtg gagtatgggc aatcgtaaat ccaatagccg gcggtgtatg tgaagcagtt
    14341 tgcggaactg catttgcagc tggatgctct gtaggttgat tttattccaa ttgttttatt
    14401 gacgttgagc ctcggaaccc ttaacaatcc caaaacttgt cgaatggtcg gcttaatagc
    14461 tcacgctatg ccgacattcg tctgcaagtt tagttaaggg ttcttctcaa catcaataaa
    14521 ttttttcggc ataaatacga tgttccttat ttatcctcat aaaaaacaat agctgaaata
    14581 tataaccaat tactgtgtgt ttgaatttct aatacatgaa tatcattctt taaaaaccta
    14641 ttaacttgtt tatctaattg acgatgagta aaagtagcga aagttttaat cttcatgata
    14701 tctctccttt tataaaaata gcaatcctta ttacaatatt aaacactttt attttggatt
    14761 ttaagaggca ttttgaagac ttagaggcaa atcatatagg ttttgtactt aaaaatctat
    14821 acagtctctt aaaacgcaaa tatgagccaa ataaatatat gctaatttca caaacaaaaa
    14881 tttcagcaaa atcagtgact aattttttag atactgccca tttacatgca aatttaaaaa
    14941 ttagcataaa atactttaaa acttccccat gtttttctaa attcctgcag ggcttttctt
    15001 atcaaaaact tagaaatttt aatttaactc taaaatctcc gtaagagcat aagggaaatt
    15061 tgctatcatt caaaaatgat agatctggca aggccagaca ttccaagggt tttaagttat
    15121 tttaaagtga tatcatacaa agctgtagtg tcacactttt gtgacactac atacagcatt
    15181 tgtcacaaaa ataagacagc acttttttac agaaaaacaa taaaaaaaga catcagttat
    15241 cactaatgtc ttaaataata attttgcttt tcgaaattcc aaattgcggt aattgaatgt
    15301 gctttttttc ttcgtctgtc gttttatctt catcacttgt attaatcaaa ttaccatctt
    15361 cggcatcgtc taagtttaaa attttatgct tttgtttaag caatccacca taacttaaca
    15421 tacgttttcg atacaaacct ttttctaaat cacttacaat ttcttgattt ttttcgtcgt
    15481 catcagttaa aaagtcagat gatttaacgg aatattttga tgtctcttcg agtgttataa
    15541 aatcatttga attattgatt aaagatatta tattgtttca tgtttttacg gcgcatataa
    15601 agggcatgtg tttcttcaag ttcagttaga attgtttgca ttaaataagc ttgcattgac
    15661 ttgattgttt ccttttggcc tttaactccc ctatcatgta tagctttttt aagtcttttt
    15721 aaagaagtta atatttcatc ctcaatgtcc tctaacatgt aatgcatatc ttcatgcctt
    15781 gaattaaatg atttttttgc tttaagaata acagccttta tgatttctaa atctctataa
    15841 tcatatttta ataaataatt agttagttgt tctgggaatt cttgcaatag catttcttta
    15901 tcatcaaaat tatgtgtaaa ttgatttgaa tgatttgaat gattactaat ttcatttttg
    15961 tactttatat cattcaagtc attcatatca ttattctcag tatcattaaa gtcaatgtca
    16021 ttaaagtcag tatcattagt gttcgatttt cgaacttctg gacgttcgat tttcgaactt
    16081 ctggacgttc gattttcgaa cttctggacg ttcgattttc gaacttcctt ctcgccgtaa
    16141 ggttcaacat cgttttcttc tttttctatt ttgtaaatat cacgttctgt gacaataggt
    16201 ttcattaaat atagaatatt tggtttattt aaaccacgtc gtttttgaat gagtagacca
    16261 tcgttttcta accctttttt tatttttgtt aacttttctt ttttacaatt taagatttcc
    16321 attagctttt catttgaata aacaaagtaa atgttaccat cttcatcaac ccagctattt
    16381 ttaatagata aatttaagcg atcacgtaag atagcatagg ctattttcat atcattagtt
    16441 agatttttat aattttcact ggtaaagaat actttaggga tttgataaaa tctttctttg
    16501 taattttctt gcactgtaaa atattgattt tgcatgacaa aaaacctctt tccatatttt
    16561 agtttggtaa gaggtaataa aacgttttta tttagcttta catttattta atgatttagg
    16621 tgcttgcact aagatattat tcattatata atacaagtat cgaaaattat ataaataaac
    16681 agtttctaaa cgttttatta ccaaaccccg actattacca gtagttgggg tttttgttat
    16741 attaagttta ttatagcact ttaaataaac ttataaaagg gaaaatatag ctttatcaag
    16801 ggtttataaa cccttgataa atatcataaa cctttcataa acccttgata aaaaggttga
    16861 tggatgttta tttttattta ttaatcactt tattattaag cattataagc ttataatatt
    16921 ttatcaaggg tttataaaca ttttataaag ggttgatgat atgaaaagtg tgaaaaagtt
    16981 gagtgaagaa ttaggggtta gtaagcaaac gatttttaat aatattaagc gattgaatat
    17041 agagacaata aaacaggaaa acacttcgtt tattaaagaa gataccgata tagaaaaaat
    17101 cattcaaaga gtaaatgaaa ataaaaagaa atatggtttt gaaagtacta ctgaagacaa
    17161 acaaaaaaaa gggtcggata atattaattt tgaatcgaaa agcgatgctc aaatagtaga
    17221 aatccttaaa aatcagattg atactttaaa taatcaaatt gaaaaacaag aaagtcgtca
    17281 tgaaacaaca attgaatttt acagaaaaga gttgcaagaa agatcaaaat tgcttgaaaa
    17341 tcagcaagtt ctggcattag agagtaataa aaagattcaa aaattagaaa atcaattaga
    17401 aaaagaaaaa caccttaatt atccctttga tacatctact aacactagac aaaacgttga
    17461 tgcacaagaa aaaacatata ctactaatcc tgtaaatatt aacagagatc aggaagaaac
    17521 taaagaaaca gagattcaat ataaggatat atctggaagt caaagcgacg aaagtacaca
    17581 aggtgaagaa gcaaaaaaag aagacgttcc agctaatcta aatgacaatg atagtgatat
    17641 agaagaaaag agtgaagaaa cggaacctaa aaaggggttt tggagtcgtt tgtttggtag
    17701 ctaaaataat tgattaggca ctaaaagtta taaaatttta gtgtctttta tatagtgaga
    17761 acttctggta atcatcgatt gtgttaacca aacaaaaagc cataaatgcc gtcatatagg
    17821 catttatggc tttttacttt cattatcttt tatgcatctt ttatacatcg ttgatttgac
    17881 gcgttttcat tcttttgcat tggcaagtat tttgtatctt tattcagtta ctatttcttt
    17941 tctccaacct aacaaaccat ctttaactct aataatatgt ttgccacgcc aggcacttct
    18001 tacttcgaaa taataccatt ccccgttttt gttgaggaaa taaatatctt gataaccttc
    18061 tttaatgaca tattttgtag cttcttgtct ttgatcgcca aacattatca atcccaccct
    18121 tatatttatt tatctttaat atataacaac atttattaat attcatgtta tttcatggaa
    18181 gaagagattt gttataatgt gaaggtcgtc tatctctcag acgtcaattc ggcgtagaga
    18241 ggaggtgcga tttatgaatg aaattcttgt tcacatcatg acaacggcaa tcagtggttg
    18301 tctcgttacg ttatttggtt attggctcca taaacgtgat aaaaaataat atagacgatt
    18361 aaagccaatt caccaaaaaa ccccgaacta cggcgaatag ttcggggttt ggtgcgttta
    18421 caaacgaaat tcttgttact tttagtatat atttcatatt gccttttgta aactcttcta
    18481 ttcttatcaa tacatttcaa ggtgtcgtaa aaatactttc ctttttcata ttgcctgatg
    18541 tgcattaaat tttgatttta aaatcaaccc atgaacgaat gaatggccca aactaaaaat
    18601 ccggcaacag gaaagaaaag ccaccaaaaa tcataaagaa aatcaactat ggaaggtgcc
    18661 ctgttactct ctctataatt tccctctaaa ataacttttt taaaacgtgc atctccttta
    18721 attaaatgct ctaaagagat tccaaataaa tcgctcatag caatcaaaat atctaaggaa
    18781 ggatagtttt tggcactttc ccatttagaa acactttgtc tggaaacctt taatatattg
    18841 gctaattcct cttgagacca tctttttaat tctctctgtt cttttatagc ttcagctaat
    18901 ttcataaaat cactccttaa ctcaaactat aattaaaata attgaaaagt cacgatactt
    18961 ttagttaacc aactcgcaac gaaaagttgc gttattccca attcagttca agttgtttta
    19021 aaaaatcctc tcgttctttc tctaattgtg ggtcgtaatc tttttgaggt tgcttttcat
    19081 atgaccgttc ttctaaccat ttaggcgtct tttcacgcct cacatattgt cttgatttat
    19141 ctatcttgga catttgaggt tgtcgtttgt tatgaatgcg tttctcagcg tcaaatgtga
    19201 actctatcca ttcaatttta cgcccttttt tcgctttgat tttattgata gtaagattat
    19261 taaatataga acctaattca ataataatag gtttaaaaac atttttgtta atatcagtca
    19321 tacgataaga tttaggtata tctaaacgat ttttaaaatc atcgatgtga atttttaaat
    19381 agcctgtatg tttgtattgt ttaagtaatc taaacatatt tttagaatat gtagatttaa
    19441 gcctagtcat ttcttttaat tcaaattttg taaaattatt agtaattgaa ttcaatatgt
    19501 gttttaaatt tgaagaagtt gatatttcta gatattgttc tcgcttatgg attctataat
    19561 gattgaataa aacgaatctt tctattacat catcatcttc atatctaatg gttaaattca
    19621 acatcttttt atacacatta tctaaatcat tagcaaatct attaatatta cgtgtttctg
    19681 gactataatt acttaatttt tttaattcat caaaagacaa acgtaatgta ttagtatctt
    19741 gctcttttaa tttattacac atcgcaaaaa ataaattaat ttcagtagct gtaaatcgcc
    19801 ttaatggaac taaattcatt tcatttttat atacaactgt ctctcctgtc atgatacagc
    19861 ccccctttat tacgaaccta aaggagtatc gtttgaatat acactcccat ttgaaaactt
    19921 ttattcacaa taaactactt tattatcaat gtcaaaccat aaaaggagta caacttttta
    19981 aaacactcct tttatgtggc aaaaacactc ctttaggcat tgaaatccct tgttgctcta
    20041 ggtctgaaca agcccctaaa agatttttaa aaagatttat aaaaatatat taaaaagtta
    20101 gaggggggct acctattttt catcctaaaa aataattaac ctcaaacaaa tgcatttaaa
    20161 tatctatttt tataatgtat aaccatcttc tctatcttct ttaaaaatga tttctcattc
    20221 ttgtgcttga tatttcttct taaagaactg ttcatcattg ttatctatcg tcattacttc
    20281 acgtatttta gaattgtcta aatgattatc aatatgattt attagcgtat gataacgctc
    20341 ttctttcatc atacttttaa tgattttaaa aacttgattg aataacttaa gcgtataatt
    20401 tagttcttta tctttctttt cattctctga caacaaataa ttataacgtt gtgctaaatc
    20461 attaaattct tcaaccagct tttcattttc catatggaca ctagtcaatt cattaactaa
    20521 actttcattt tgtttctctg atttttttaa tgacttccca cttttaatcc attcataatc
    20581 atctaatatc atctgtgctg ctttaatttg tttagtgtat ttttcaaaat aagttttagt
    20641 aattacaata ttgcctgttt cttgcttctc tttatgaaac catccaccta catttttagt
    20701 tttaatttca tacatgacac tcagaagctt tttaagcgta tctaatgatt tttggtagtt
    20761 ttgtatcaat ttatcatttt cttactttaa atgatcctct atttgcttct cgcgcatata
    20821 catttgttta tgatattctg ttttttgttt atagccgcta acttgatcat gtttttcttt
    20881 tgtaagttgt ctagaaattc ctcgttttaa atcatagcct tgcttattaa tatacgtatt
    20941 gaatctatct tggaattcgg ttaatgcttt tttattacct acaacttctt tcgcacttaa
    21001 acgtccatct ttagtaatag gaattacgcc ataatgcata tgtggtgtta tctcatccat
    21061 atgtactgtc gcatataaaa gattttcttt accgtattct tcttccaaga acgctttagc
    21121 atgcttaaaa aactattttg tctcttcttc agataattga ttaaaaacac attatctgat
    21181 gtaattaatc catcaatatg tttaatggca tctgttctaa ttttgcgttt ccctttataa
    21241 ttttgttcga ttttctcatc aattttttta ttaaaatcaa acttagtatc attgactaaa
    21301 tcatagttta aatatgactt acttaaatca atatctatat tttcataatt tttattttct
    21361 ctttgaatac ctcttgtatt tgtttttgat ttcactttaa caactcgaat aattgaataa
    21421 gacataataa atcaacttcc actgcatatg attataacac ctaaacacag aaaagtttta
    21481 acatactaga cttattaaaa accaaataag tcattaaaaa cgtgtgctct gcgaggcttg
    21541 ttttttgtca tcacaaaaaa ggactggaaa atccagtcct taaattaaaa aactcaaaag
    21601 taatgactaa tcatatttca tattgttttt tctctatgta tggctatacc tatcaatatt
    21661 tcttaacttc taagctcaga aatattgact atgacatcaa atcgtttcgc aagctctaaa
    21721 tcatgcgtta cgacaatcat agttttattt tcatcaagta gcttcaataa taaatcaata
    21781 actatttttc catttttcgt atctagtgat ccagtaggtt catcagctaa aatgattttc
    21841 ggatctttta atattaatct tgccaatgct actctttgtt gttcaccacc gcttagagaa
    21901 ctaacaattc tcttgatatc taaatctagg ccgacctttt ttaatacttc tttctttaag
    21961 ttcatattat cttttttatt ctttttgaac tttagggcta aatctaaatt ttgactgatt
    22021 gtttgatttt caagtaaagc aaaattttga aacaaatacc ctaacgtata tctataaaaa
    22081 tcgactttct tttttagtaa cttatcttca atatatatgc ttccttgtga tacatcttcg
    22141 aacccagcga ttatgttaag taaagtagat tttccagcgc cactttctcc aactaaagca
    22201 tatgattttc ctttttcaaa attaaagtta catccgtcta aaatgttttt attacctttt
    22261 tttacaaaaa cattttcaag ttttatcact atcggtcacc tcattttaaa aagctaggaa
    22321 tatcttttgt aatgtattct atcgaacgca catatttccc tttatgattt actttcacat
    22381 attcttttgt aggatcataa cctaaaaaat ccaatttata actctttttt tctccatttt
    22441 tagagtatac agttatattt ctatagtcct gggtatcttt tggaactttg gcataagata
    22501 ctttttcttt taacagtggg ttaaaacgat ctaaatgctc atttctaacc aataacagac
    22561 taagtatgat gattaatagt acaattgtta caataattaa agttcttttc attgtttaaa
    22621 tctccctcat taaatcttta aagtattttt caagatattt aatataagca atttgaagta
    22681 aatgttgaat aatagcaata gacattatta tgaatagtaa tatctttgaa ccaaataaaa
    22741 tatgcgtagt gtaagctaac ataatagaaa gtaaaataga aattgttaaa taacgtacat
    22801 tactgctgaa taatgaataa ccatgaattt ttcttaataa tagttgcttt ttattccagc
    22861 taaaatattg aattgtttca aatacagtag ctatcaaaag aatgaaaacg ttaataataa
    22921 tagtaactat tgttattatc atttttgttt tcgtttcatt taattcattt aacacagaat
    22981 ccttgtaatt agttataccg ctaatttctt cttctaggtg attatcttta agcaactgtt
    23041 taagtgtatc taaatcttta aatagatatc caccttgaga aacagcagct aaataaaaat
    23101 ctcctgttaa atcgtcaggt gtcaacaaca ttactattgg agaatctaga tatccaaatt
    23161 tcaaattagt tgtgcgatca aaagaaaaaa cagatacgtt ttttgacagt acttgcacat
    23221 ctactttttt gttttgttgc ttttgaaagt caatccatcc ttggtgattt ttttgaattt
    23281 cagatttttg atattgtaac cttggaggaa taaacacgtt tattttatcc gaatgattgt
    23341 caatcatttt aaaatcatga tttatatttt tatagaaatt cagaaaattg ttattgataa
    23401 aaaagacatt gccattttca ggaatgtaat tgtttttatc gggattggct atattattat
    23461 tctttaaaag caatccacca agttgttcgc ttttcttaat taaattgtat atattagttt
    23521 ctaaaatttg tttttcttct gaatttctaa tattaggaga aatctctaat gtatagtaat
    23581 tatctaactt ttgccagatt ttttcagagt catatatatt ctttaacttc gtataagcat
    23641 ttaaattttg tgccagtaaa aaagatagta ttagcaccat gatacatttg gtgaaggtac
    23701 ccataaatat tgaaaactta tatccttttt tcccttttaa ggttaatgga atacttaact
    23761 tcaaaagaag actatacgaa atcagccaca acaatgtagt aatacaagca aaaacaaaaa
    23821 gcaacacgat aaatctacga ataaacatta agaaatccaa ttctaaattg gctatatgaa
    23881 tgattaatat attagcaata aagaaaatag tggtaagtac tagccaataa atgattttta
    23941 tatgaatatt atgaaaaata atgcgtgtag ttgaaaagcc atgtagcttt tgaatagcat
    24001 aaaatttcaa attatatcct ctgtcatata agaagtacaa aagatataat acgcctaaga
    24061 atatgaaagg cactaataaa tcattatcta tgactaattc aaaaaataat atgtttctat
    24121 ttatgtattc aacttcagat gttaaaccag ctttttttaa ttcactcgta agctcttcta
    24181 cattgaaatg ttcaccaata atataatact ttccttttat ctctctgttt aataaatctg
    24241 atggagttaa aagtgatgtt ttattacgta taaagtcaga attatttcgt tttgagttga
    24301 aaacaaaaaa ttctttttta ttatcaaaat ctttaacgga tttaattatt tgtatatttt
    24361 gatttttggc gcctgattca atgacatcta acacttttga tttactgtta gatttatccc
    24421 aattagagat tgttaaaata ttggaacttt caggtataat ttcttcattt tctttgaaga
    24481 aaaataaaaa taatagccct gaaattaata ataaagtact aaaatctaaa aataatttga
    24541 attttttcat attgcctctt tcaagagaat agacagaatt aagtttactt aattctgtct
    24601 attctcctta attaatatat gtaattagtg aagactataa aatgttttgt ttcc
//
