LOCUS       NZ_CP098823            22579 bp    DNA     circular CON 18-MAY-2024
DEFINITION  Staphylococcus capitis strain XWZ plasmid unnamed3, complete
            sequence.
ACCESSION   NZ_CP098823
VERSION     NZ_CP098823.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN23101376
            Assembly: GCF_039641285.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus capitis
  ORGANISM  Staphylococcus capitis
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 22579)
  AUTHORS   Chen,Y. and Wang,Z.
  TITLE     Epidemiological analysis of linezolid-resistant Staphylococcus
            capitis outbreak in Chinese hospitals using Core Genome Multilocus
            Sequence Typing (cgMLST)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 22579)
  AUTHORS   Chen,Y. and Wang,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-NOV-2021) Infectious Diseases, Zhejiang University, 3
            East Qingchun Road, Hangzhou, Zhejiang 310016, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200x
            Sequencing Technology             :: Illumina; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_039641285.1-RS_2024_05_18
            Annotation Date                   :: 05/18/2024 10:54:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,641
            CDSs (total)                      :: 2,558
            Genes (coding)                    :: 2,514
            CDSs (with protein)               :: 2,514
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 44
            CDSs (without protein)            :: 44
            Pseudo Genes (ambiguous residues) :: 0 of 44
            Pseudo Genes (frameshifted)       :: 14 of 44
            Pseudo Genes (incomplete)         :: 29 of 44
            Pseudo Genes (internal stop)      :: 9 of 44
            Pseudo Genes (multiple problems)  :: 7 of 44
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP098823.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..22579
                     /organism="Staphylococcus capitis"
                     /mol_type="genomic DNA"
                     /strain="XWZ"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:29388"
                     /plasmid="unnamed3"
                     /geo_loc_name="China: Hangzhou"
                     /lat_lon="30.25 N 120.20 E"
                     /collection_date="2012-02-04"
                     /collected_by="Sir Run Run Shaw Hospital"
     gene            79..1035
                     /locus_tag="NF323_RS13095"
                     /old_locus_tag="NF323_13085"
     CDS             79..1035
                     /locus_tag="NF323_RS13095"
                     /old_locus_tag="NF323_13085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017175392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_009385105.1"
                     /translation="MSRKNIKNQANQNFYMLHKALFVNEKYKKLSDSAKVTYAILNDRV
                     SLSIKNNWVDDNGDIYFIFTNESLQNILDKSKNTITKIKKELQAVGLLEQIRTGFNKPN
                     KLYLHDIETNINVEKSIQSSSITYNDKESQNLGLQNPEFWDSRFSKFGTPESQILDPND
                     TDYNDTDYIKTENNDTDDLNDNKLTFPSNHTNHSNHDNSNFNNEALKFQLLEELPQSIQ
                     NYLSNFEVAEIKIIKTVLLKAKTSFNNAIDSYYLLEDMEIEILHVLKRFKAMLIQKNET
                     VESMQGYLMKSLKSEFAEMHTLNKRRDHLPITSLFNQ"
                     /name="replication initiator protein A"
     gene            2582..3067
                     /locus_tag="NF323_RS13100"
                     /old_locus_tag="NF323_13090"
     CDS             2582..3067
                     /locus_tag="NF323_RS13100"
                     /old_locus_tag="NF323_13090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002455937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_009385108.1"
                     /translation="MKKFSKIVLASGIVLGFSVTPELFNATEAQAQESIEPYYNYDGYT
                     AYQSGFILDKNFKESLKYDNFTINGYQISKNQTGNNRINLYDQTLYGVSENKANGVFFS
                     LDGKSINKNTLIQNYGKPNSYSPTSAWGEEYMYKIGNKDVRFYIYNGYVIKCQIISE"
                     /name="hypothetical protein"
     gene            3356..3739
                     /locus_tag="NF323_RS13105"
                     /old_locus_tag="NF323_13095"
     CDS             3356..3739
                     /locus_tag="NF323_RS13105"
                     /old_locus_tag="NF323_13095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="WP_009385109.1"
                     /translation="MKLYVNEIVRTNNFEDDDIMNKILGMWDTFYKNNDDYKGKVYAIY
                     HDYESDYKGDYSLALCTEDISADKFFEVDFANSIEYKCSGKDEIANVWKRIWEDEEENK
                     IQRKYDIDCEEYKEDGSVVIHLF"
                     /name="effector binding domain-containing protein"
     gene            3910..4011
                     /locus_tag="NF323_RS13110"
                     /old_locus_tag="NF323_13100"
     CDS             3910..4011
                     /locus_tag="NF323_RS13110"
                     /old_locus_tag="NF323_13100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_000228874.1"
                     /translation="MVEALVHITTTVISGCIVALFTHWLRTRNNKKK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            4125..5501
                     /locus_tag="NF323_RS13115"
                     /old_locus_tag="NF323_13105"
     CDS             4125..5501
                     /locus_tag="NF323_RS13115"
                     /old_locus_tag="NF323_13105"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_141519824.1"
                     /translation="MQKVKGGIMENISGNRYIYHYHIFESSTNTFDSKSLNLIPEVLPI
                     IAISDFNSQRKNNYGFITKNHDYLEKEGFYQEIMKYVGRGYLESERNYYNYVAMDSYSD
                     YKSYFLAPIVFEKNNETIYIYLTLKIFSQGIFYIEVTDELDKLNFTDDNFNIIENGEDC
                     RILFPIMENKNIKYIERDIEEGIINTFVDEYHKFIFKAMENIYQKKTVHTYFTLFILDD
                     GILNGKNNIDKSKEIAAAPYFKNLGTHFSNSVKSFDFNHFKFFGNINRIVVNLKSGGKD
                     YTISKKTYKEDKYYYRGINNAFIMSALNYIYIKKSILNFLAETTYNNNPINREWLNFLE
                     KNIIQGYSLKYVPSHDLRKMIDEQFIDSKEFETIQRLHYDNANIQLSKKQEVVETKINL
                     LNLIVFIFTILSIAQIVEIFTDNKKIIAIITSAIFLITIAIIFFVNYIYTKKKRNNIDH
                     "
                     /name="hypothetical protein"
     gene            complement(5571..6098)
                     /locus_tag="NF323_RS13120"
                     /old_locus_tag="NF323_13110"
     CDS             complement(5571..6098)
                     /locus_tag="NF323_RS13120"
                     /old_locus_tag="NF323_13110"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="WP_001831394.1"
                     /translation="MIKFEYFEEKDFDLLINWINSPELLVKWAGTDFNYPLDEEQLKEY
                     IKDTNKENSSKIIYKVIIEENNSKKIIGHIALNNIDFKNCSATLSKVLVGDPQMRGQGL
                     GPKIIKKLLKKAFEDLGLHRIELGVFAFNKSAIKSYKKIGFIKEGEKRDFRKLNGEYYN
                     LWQMSMLESEWS"
                     /name="GNAT family protein"
     gene            complement(6291..6947)
                     /locus_tag="NF323_RS13125"
                     /old_locus_tag="NF323_13115"
     CDS             complement(6291..6947)
                     /locus_tag="NF323_RS13125"
                     /old_locus_tag="NF323_13115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002489266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001831384.1"
                     /translation="MNHNHEYHSNKPEIKANVVYRDGNIEITLEDEFNNAPLLDTMHEK
                     EMHFVLVSNDMEKYYHLHPQKKHEGLFIINQQLEPGTYQAFVDVTPKNHVYSVHPIELQ
                     IGDKITSTTSLNSDKNWVKVNKGVHVTLNSISAKEDEHVPLTFNTELTPQPYLGALGHV
                     IIFDEQLTDYIHVHPESPDSTTFYAHFPKKGMYKIWAEFKFNDEVHRFTYNIKVA"
                     /name="hypothetical protein"
     gene            complement(7011..7220)
                     /gene="copZ"
                     /locus_tag="NF323_RS13130"
                     /old_locus_tag="NF323_13120"
     CDS             complement(7011..7220)
                     /gene="copZ"
                     /locus_tag="NF323_RS13130"
                     /old_locus_tag="NF323_13120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001831373.1"
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="WP_001831373.1"
                     /translation="MTNEVINVEGMSCDHCKHSIEKALNGLDGVTSSEVSLANGNVEVE
                     FDENQVAFNDFKEAIEDQGYDVIK"
                     /name="copZ"
     gene            complement(7254..9641)
                     /locus_tag="NF323_RS13135"
                     /old_locus_tag="NF323_13125"
     CDS             complement(7254..9641)
                     /locus_tag="NF323_RS13135"
                     /old_locus_tag="NF323_13125"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002485948.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0019829 - ATPase-coupled monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="WP_001832797.1"
                     /translation="MSENIKKTSLGITGMTCAACSNKVEKNLNKLDEVNANVNPSTEKA
                     TIEYNPNVTSLEDIANTIQKTGYGVLTEKVDLDVMGMTCAACSNKIEKVLNRISGVNKA
                     TVNLTTESATVEYNPDMTSVDEFQQRIKNLGYEAQPKKEASEKSSQKEKQLKRQLIKLV
                     VSAVLAAPLLMTMFVHLFGIQIPHIFMNPWFQFVLATPVQFVIGWQFYVGAYKNLRNGS
                     ANMDVLVALGTSAAFFYSIYESIKWLINTNYEPHLYFETSAVLITLILFGKYLEARAKT
                     QTTNALSKLLNLQAKEARILRNGEETMVPLSEVKEGDYLVIKPGEKIPVDGKIIKGMTS
                     IDESMLTGESIPVEKMQNDNVIGSTMNKNGAITVEATKVGKDTALASIVKVVEEAQGSK
                     APIQRLADIISGYFVPIVVGIAIFTFIIWISLVQPGQFEPALVAAIAVLVIACPCALGL
                     ATPTSIMVGTGKAAENGILFKGGEHIEGTHAINTVVLDKTGTITNGTPEVTDFSGDDQT
                     LQLLASAEKGSEHPLAEAIVSYAKEKSLEFLEVDHFEAIPGRGINATIDGKELFVGNRK
                     LMSEKGIQTNEAETNLAQFEKEGKTAMLISVDNELRGVVAVADTVKDTAQQAIQKLHEL
                     GIEVAMLTGDNKRTAQAIAKQVGIDTIIAEVLPEEKASKVAEIQSEGKKVAMVGDGVND
                     APALVKADIGIAIGTGTEVAIEAADITILGGDLLLIPKAIKASKSTIRNIRQNLFWAFG
                     YNVAGIPIAAIGLLAPWVAGAAMALSSVSVVTNALRLKRMKL"
                     /name="heavy metal translocating P-type ATPase"
     gene            complement(9656..9931)
                     /locus_tag="NF323_RS13140"
                     /old_locus_tag="NF323_13130"
     CDS             complement(9656..9931)
                     /locus_tag="NF323_RS13140"
                     /old_locus_tag="NF323_13130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001831396.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0046872 - metal ion binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
                     /protein_id="WP_001831396.1"
                     /translation="MNTTTVKNNDALLNRLKRLEGQMRGLQSMIAEDRYCIDVLVQITA
                     IQSALKQVGFIVTEDHISNCVSEGIKNGNGEESIKELMVVLKQFSK"
                     /name="metal-sensing transcriptional repressor"
     gene            10106..10381
                     /locus_tag="NF323_RS13145"
                     /old_locus_tag="NF323_13135"
     CDS             10106..10381
                     /locus_tag="NF323_RS13145"
                     /old_locus_tag="NF323_13135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002489264.1"
                     /GO_function="GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin family protein"
                     /protein_id="WP_002489264.1"
                     /translation="MDKNIQLELYTRPTCSDCQESKRYLNSQEISYSHKDVSQNLDLEE
                     EMKKISGNRIVPLFVFYKKNFWGKKKLFKYYVGFENNKKDILNILE"
                     /name="glutaredoxin family protein"
     gene            complement(10422..11363)
                     /locus_tag="NF323_RS13150"
                     /old_locus_tag="NF323_13140"
     CDS             complement(10422..11363)
                     /locus_tag="NF323_RS13150"
                     /old_locus_tag="NF323_13140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002449936.1"
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_030063651.1"
                     /translation="MENDHNHNHTHGANKKTLLISFIIITSYMIVEGLGGFFTNSLALI
                     SDAGHMLSDSISLGIALIAFTLGAKQANTNKTFGYKRFEILAAVLNGITLMLIAIYIFY
                     EAIERFKNPPEVASTGMLIIALVGLFINIIVAWIMLRGSDVEENLNMRGAYLHVISDML
                     GSIGAVIAALLIIFFRWGWADPLASVIVAILVLRSGFYVTKSSLHVLMEGAPSNINTKD
                     IIKTIKKFKEVKNIHDFHVWSVTSGLNALSCHIVVEDTMTITENEFLLKRIEHELNHQN
                     IQHVTIQTETSNNNHSEKLFCIVKEKDSQHHH"
                     /name="cation diffusion facilitator family transporter"
     gene            complement(11769..12141)
                     /locus_tag="NF323_RS13155"
                     /pseudo=""
     CDS             complement(11769..12141)
                     /locus_tag="NF323_RS13155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002487969.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated family protein"
                     /name="replication-associated family protein"
     gene            12334..13008
                     /locus_tag="NF323_RS13160"
                     /old_locus_tag="NF323_13150"
     CDS             12334..13008
                     /locus_tag="NF323_RS13160"
                     /old_locus_tag="NF323_13150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_016931271.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRVDETYIKIKGKWYYLYRAIDADGHTLDIWL
                     RKKRDNHSAYAFIKRLIKQFGKPQMIITDQAPSTKVAMSKLIKDFKLNPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSVNTAKNTLKGIECIYGLYKKNRRSLQIYGFSPCYEINHML
                     AS"
                     /name="IS6 family transposase"
     gene            13303..13977
                     /locus_tag="NF323_RS13165"
                     /old_locus_tag="NF323_13155"
     CDS             13303..13977
                     /locus_tag="NF323_RS13165"
                     /old_locus_tag="NF323_13155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_010775116.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYRIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQSPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(14144..15583)
                     /gene="aph(2'')-Ia"
                     /locus_tag="NF323_RS13170"
                     /old_locus_tag="NF323_13160"
     CDS             complement(14144..15583)
                     /gene="aph(2'')-Ia"
                     /locus_tag="NF323_RS13170"
                     /old_locus_tag="NF323_13160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="WP_001028144.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLES
                     LKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFIGE
                     PNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLPEHE
                     LHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNE
                     YIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTF
                     LTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIY
                     NDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGI
                     IDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIK
                     NIKQEFIENGRKEIYKRTYKD"
                     /name="aph(2'')-Ia"
     gene            15687..16361
                     /locus_tag="NF323_RS13175"
                     /old_locus_tag="NF323_13165"
     CDS             15687..16361
                     /locus_tag="NF323_RS13175"
                     /old_locus_tag="NF323_13165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_010775116.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYRIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQSPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            16572..16898
                     /locus_tag="NF323_RS13180"
                     /old_locus_tag="NF323_13170"
     CDS             16572..16898
                     /locus_tag="NF323_RS13180"
                     /old_locus_tag="NF323_13170"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_030063388.1"
                     /translation="MNTLNTVMLCIGLFFVIPSMIYLTIYYIVNTIVLYQKSKTKTSIS
                     TNIYGVKEIKYNVSPRLLRIQTKLKENRVFGAIGFVFGLFMIDIPLLYILLEFLKDFLP
                     SLSF"
                     /name="hypothetical protein"
     gene            17388..17996
                     /locus_tag="NF323_RS13185"
                     /old_locus_tag="NF323_13175"
     CDS             17388..17996
                     /locus_tag="NF323_RS13185"
                     /old_locus_tag="NF323_13175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583537.1"
                     /translation="MIIGYARVSSVDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEVINTVNYLKDKEVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIVQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKNGKGLS"
                     /name="recombinase family protein"
     gene            complement(18201..18767)
                     /gene="qacR"
                     /locus_tag="NF323_RS13190"
                     /old_locus_tag="NF323_13180"
     ARG             complement(18205..18767)
                     /name="qacR"
                     /gene="qacR"
                     /gene_name="multidrug-binding transcriptional regulator
                     QacR"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="99.47"
                     /coverage="100.0"
     gene            18945..20489
                     /locus_tag="NF323_RS13195"
                     /old_locus_tag="NF323_13185"
     CDS             18945..20489
                     /locus_tag="NF323_RS13195"
                     /old_locus_tag="NF323_13185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux MFS
                     transporter QacA"
                     /protein_id="WP_000622776.1"
                     /translation="MISFFTKTTDMMTSKKRWTALVVLAVSLFVVTMDMTILIMALPEL
                     VRELEPSGTQQLWIVDIYSLVLAGFIIPLSAFADKWGRKKALLTGFALFGLVSLAIFFA
                     ESAEFVIAIRFLLGIAGALIMPTTLSMIRVIFENPKERATALAVWSIASSIGAVFGPII
                     GGALLEQFSWHSAFLINVPFAIIAVVAGLFLLPESKLSKEKSHSWDIPSTILSIAGMIG
                     LVWSIKEFSKEGLADIIPWVVIVLAITMIVIFVKRNLSSSDPMLDVRLFKKRSFSAGTI
                     AAFMTMFAMASVLLLASQWLQVVEELSPFKAGLYLLPMAIGDMVFAPIAPGLAARFGPK
                     IVLPSGIGIAAIGMFIMYFFGHPLSYSTMALALILVGAGMASLAVASALIMLETPTSKA
                     GNAAAVEESMYDLGNVFGVAVLGSLSSMLYRVFLDISSFSSKGIVGDLAHVAEESVVGA
                     VEVAKATGIKQLANEAVTSFNDAFVATALVGGIIMIIISIVVYLLIPKSLDITKQK"
                     /name="quaternary ammonium compound efflux MFS transporter
                     QacA"
     gene            20694..21254
                     /locus_tag="NF323_RS13200"
                     /old_locus_tag="NF323_13190"
     CDS             20694..21254
                     /locus_tag="NF323_RS13200"
                     /old_locus_tag="NF323_13190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001077893.1"
                     /translation="MNRADIFKIFDVELNITIFLGALVATFIYFISYMNNVNELITLCL
                     TLAFPAYLLKISRSFEVILLEEKIKNSKIKICDKDRIEREILVKKNLIDELLFPNRVIK
                     KYTLTILIYSIGIIILLLLCNMLSYGIGENVNFIWRLLACYVTSVTVIIVALIIMIMIF
                     DLIIGLLLNFQIFLKNKKYDDFL"
                     /name="hypothetical protein"
     gene            complement(21577..22272)
                     /locus_tag="NF323_RS13205"
                     /old_locus_tag="NF323_13195"
     CDS             complement(21577..22272)
                     /locus_tag="NF323_RS13205"
                     /old_locus_tag="NF323_13195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002500633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_009385103.1"
                     /translation="MKSVKEISEELEVSKQTVFNNIKRLNIETVKQDNTSFIKNDVDVE
                     KIIQRVIRNKKKYGFESANVSSEKVKTDNKKNESKYDVQIIELLEKQIDTLNKQLEKQE
                     KRHETTIEFYRKELQERSKLLENQQVLALESNKKIQSLESELEEERQLNYSANKRQDIE
                     VQETMENMDSINNDSDSQKEKMVSHFRDESKDKHEDKQQGNKIDGEQKEDIRNENHSKK
                     SFWSKLFGN"
                     /name="DUF536 domain-containing protein"
     ARG             18946..20486
                     /name="qacA"
                     /gene="qacA"
                     /gene_name="quaternary ammonium compound efflux MFS
                     transporter QacA"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(14148..15583)
                     /name="aac(6')-Ie/aph(2'')-Ia"
                     /gene="aac(6')-Ie/aph(2'')-Ia"
                     /gene_name="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(14145..15583)
                     /name="AAC(6')-Ie-APH(2'')-Ia bifunctional protein"
                     /gene="AAC(6')-Ie-APH(2'')-Ia bifunctional protein"
                     /gene_name="aminoglycoside bifunctional resistance protein"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          2..1035
                     /name="rep_cluster_910"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="97.295"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ttgcaagtca aaaagttatg tggatttgta atgttttatt acctctattc aaatttaatt
       61 ggaaagaggt tttttattat gtctcgtaaa aatattaaaa atcaagcaaa tcaaaacttt
      121 tatatgctac ataaagcatt atttgttaat gaaaaatata aaaaattaag tgatagtgcc
      181 aaagttactt atgcaattct caacgataga gttagcttgt cgattaaaaa taattgggtc
      241 gatgataatg gggatatata tttcattttt acaaatgaaa gtctccagaa tatattagat
      301 aaaagcaaga atacaattac taaaataaaa aaagaacttc aagcagtagg gttacttgaa
      361 caaatacgta caggatttaa taaacctaat aaattatatt tgcatgatat agaaactaat
      421 attaatgtag aaaaaagtat tcaatcctca tctataacct ataatgacaa ggagtcccaa
      481 aatttgggac tccagaatcc cgaattttgg gactccagat tctcaaaatt tgggactcca
      541 gaatcccaaa ttttagaccc taatgatact gattataatg atactgatta tattaagact
      601 gagaataatg atacggatga tttgaatgat aataaactaa cttttcctag taatcataca
      661 aatcattcaa atcacgacaa ttcaaacttt aataatgagg ctttaaaatt tcaattactc
      721 gaagaactac cgcaaagtat tcaaaactat ctaagtaact ttgaagtagc tgaaattaaa
      781 attatcaaaa ctgtattatt aaaagccaaa acatctttca acaatgcgat tgatagctac
      841 tacttgttag aagatatgga aatagaaata cttcatgttc ttaaacgttt caaagctatg
      901 cttattcaaa aaaatgaaac cgttgaatca atgcaaggat acttaatgaa atctcttaag
      961 tctgaattcg ctgaaatgca tacacttaat aaacgacgtg atcatttacc catcacttct
     1021 ttatttaatc aataatgatt taattagaga gcatctttaa atagatgttc tcttttttta
     1081 ttaacaagtg gttgctaagg caaccaccta gatcaaacaa aaataaggga ggggataaca
     1141 aaataacatc aacacaatat cgaaacatag catgctgcta ttaaagaaag gaggaatact
     1201 tatgagtact aagaaaaaga ttaaagttac tttggcaatg attaatgttc ttttaactgc
     1261 agtcgaactt tatcttcaat ggcaattgag taaatctgaa aatgaactgt agttaagcaa
     1321 gtaggtggga ctaaaacgtt tctgttttag tcctattttt tctataaacg gttattattc
     1381 gtttgaaaat ggctcaaaca agtcgcataa gatgaaaaat aaaatgatca tttaacgttg
     1441 ttttaacttt aaaaattata aaaatactaa ccgtttttat attctttagc aatctttcgt
     1501 agttataaaa gtgacttaat aaaatcgttt ttgctattta ttttgttaaa gattgaaaaa
     1561 aagggttgaa tttattattc caaaaaatca aaattcagat tcaattgata tacatcataa
     1621 acaaaaagta agtcgttaat gttcaagaca tgggtcgaat ataattttaa atttgaattt
     1681 ttttatccca aactaagtaa atatttttac ttagttttct ctttttttat cttcaatcat
     1741 tttactaaca atggttatct tgaaaataaa aataagcact taaagtaaaa agtgaataag
     1801 agaatagcca cttttgtctt aaagcacgtt ttgtttttgg aaatattaca aacatgagag
     1861 tctttttaaa gagtatttga catgagcata aggaaatcta gtaccacctt tggtggtatt
     1921 cagcatagct gaaagattta ccttttattc gttctactca attgttcatc ataaatagct
     1981 taaaagcttt atatacaggt gattatgagc attcttatac attggactga agggtgtaat
     2041 ataacacttt aatacagact ctttacaatt attacaagac cacttttaat tgtctgaata
     2101 ctcctttttt tgttgatttc ataggcctca ggcgacgtcg agactcttaa gagtcttaat
     2161 ttttttaacc aaagactctt aagactccta cttttagtat taatttcaac aacaaaatca
     2221 ctaaaaaagt aatctaagca attcatacat ttgtttcact ttttgaaatt gattaaatac
     2281 ttttttctca atatcaaatt caataatgat catattattt atttttaagt tcaaaaaaag
     2341 agaaagaata aaacaatttt tatacgtttc tatgctcaat tttattaaaa agtgactcga
     2401 aataaagagc taagtattat ttattttaga ctgtctaaag aaataaaaga gaacggaaaa
     2461 catgcccaat tgcattttct aaaaaagatg aattttttgt aatatttttg taatccggat
     2521 gactttttgt tacatttctg taataatcat agatgaatta taaataatta ggagggtttt
     2581 tatgaagaaa ttttctaaaa ttgttctagc tagcggtatt gttttgggtt tctctgtaac
     2641 gcccgaacta tttaatgcaa cggaagcaca ggcgcaagag tctattgaac cttattataa
     2701 ttatgatggt tatactgcgt atcaaagtgg atttatatta gacaaaaatt tcaaagagtc
     2761 attgaaatac gacaatttta ctatcaacgg ctatcaaata tcaaaaaatc aaacaggtaa
     2821 caatcgaata aatttatacg atcaaaccct ttatggtgtg tctgagaata aagctaacgg
     2881 tgttttcttc tctctcgatg gaaaatctat taataaaaat actttaattc aaaattatgg
     2941 caaaccaaat tcttactctc ctacttcagc atggggtgaa gaatatatgt acaaaattgg
     3001 taataaagat gtcagatttt atatttacaa tggctatgtg attaaatgtc aaattataag
     3061 tgaataagac agtttaggta taaaacgtga ggtaagttgc aagttcactt acttcacgtt
     3121 tttttattta aagtggataa aataaataat aggacacgca tttatgccga gaaaatttat
     3181 tgatgttgag aagaggcatt aactaaactt gtagacgaat gtcggtatag cgtgagctat
     3241 taaaccgacc attcgacaag ttttgggatt gttaagggtg ccgaggctca acatcaataa
     3301 agtaattgga ataaagcaat gtttttagta aattaaaaag aaaaggggtt tttttatgaa
     3361 gctatacgtt aacgaaattg ttagaacaaa taactttgaa gatgatgata ttatgaataa
     3421 aattttaggg atgtgggata ctttttataa aaataatgat gattataaag ggaaagtata
     3481 tgcaatttat catgattatg aatcggatta taaaggtgat tattcattag ctttgtgtac
     3541 agaagatatt tcggcagata aatttttcga agttgacttt gctaatagta ttgaatacaa
     3601 gtgttctgga aaagatgaaa ttgcaaacgt atggaaacgt atttgggaag atgaagaaga
     3661 gaacaaaatt caaagaaaat atgatattga ttgcgaagaa tataaagaag atgggtcagt
     3721 tgttatacat cttttttagc ttttatgaaa cgagtttctt cttgtcttga tactataaaa
     3781 ataagcaaag atataacata aaatgactta tcggaagtta tatgtaactc atctagtaca
     3841 gatgatataa tatacaggtc gcctatctct caggcgtcaa tttagacgca gagaggaggt
     3901 gcatatcaga tggtcgaagc tcttgttcac atcacgacca cagtcatcag tggttgtatt
     3961 gttgcgttat ttacgcattg gctacgtaca cgtaacaata agaaaaaata ggcgatatta
     4021 gccaacacct aaaaaccccc tcactactcg caatagtgag ggggttggtg catataatgc
     4081 acgaagctct tgttatctaa attataacac tggttagtag aggaatgcaa aaagtaaaag
     4141 gaggaattat ggagaatata agtggaaata gatatattta ccattaccat attttcgaaa
     4201 gttcaacaaa tacgtttgat tcaaaaagtt taaatttaat tcctgaagtg ttacctatta
     4261 ttgctataag tgattttaat agccaacgaa aaaataatta tggatttata actaaaaatc
     4321 atgattattt ggaaaaagaa ggattttatc aagaaattat gaaatatgtt ggaagaggat
     4381 atttggaatc tgaaagaaat tattataatt atgtagcaat ggattcatat tcagattaca
     4441 aatcatattt tttagcacca atagtttttg aaaagaataa tgaaacaatt tatatatatt
     4501 taactttaaa aatattttca caaggaatat tttatatcga agttactgat gaattagata
     4561 agttaaactt tacagatgat aactttaata taatagagaa tggagaagat tgtagaattc
     4621 tttttccaat tatggaaaat aaaaatatta aatatataga aagagatatt gaagaaggta
     4681 ttattaacac atttgttgat gaatatcata aatttatatt taaagcaatg gaaaacatat
     4741 atcaaaaaaa gactgtccac acatatttca cgttatttat attagatgat gggatattaa
     4801 atggaaaaaa taatatagat aagtcgaaag agattgcagc tgctccatat tttaaaaact
     4861 taggaacaca cttttcgaat agcgtaaaaa gttttgattt taatcatttt aaattttttg
     4921 gaaatataaa tagaatagtt gttaatttaa aaagtggagg gaaagattat acaatatcca
     4981 aaaaaactta caaagaagat aaatattact ataggggtat caataatgct tttattatgt
     5041 cagcattaaa ttatatttat ataaaaaaat caattttgaa ttttttagct gaaacaacat
     5101 ataataacaa ccctataaat agagaatggt taaatttttt ggaaaaaaat attatacaag
     5161 gatattcttt aaaatatgtt ccttcacatg acttaagaaa aatgatagat gagcaattca
     5221 tagatagtaa agaatttgaa actatacaaa gattacacta tgataatgcc aatatacaat
     5281 tgagtaaaaa acaagaagta gttgaaacaa aaattaatct tttgaattta atagtattca
     5341 tctttactat tctatctata gcacaaatag ttgaaatatt tactgataat aaaaagatta
     5401 tagcaattat aacaagtgca atttttctaa ttactattgc tataatattt tttgtaaatt
     5461 acatttatac taagaaaaag cgaaataata ttgatcatta agagtacgct ctaaataaac
     5521 aaaaatagtc ctcttattaa aataagagga ctatttttgt ttaaaattat tcaagaccat
     5581 tcgctttcta acatactcat ttgccataaa ttataatatt ctccatttaa ttttctaaag
     5641 tctctttttt ctccttcttt tataaatcca atctttttgt aacttttaat agctgattta
     5701 ttaaaggcaa aaacacctaa ttcaattctg tgtagtccca aatcttcaaa agcctttttc
     5761 aataatttct ttattatttt agggcctaat ccttggccac gcatttgcgg atcacctact
     5821 aaaactttac ttaacgtggc ggaacaattt ttaaaatcta tattatttaa agcaatatga
     5881 cctataattt tttttgaatt attttcttca atgataactt tataaattat tttactagaa
     5941 ttttctttat ttgtgtcttt aatatattcc tttaattgtt cttcatctag gggataatta
     6001 aaatctgtac ctgcccattt gactaaaagt tcaggagagt ttatccagtt tattaataaa
     6061 tcaaaatctt tctcctcaaa atattcaaac ttaatcaata aattactcct taaataatag
     6121 gttattaact ataaaaattc agtgaatgtt gcaatataaa caaccactac aattttttga
     6181 tactttcttc atcaactttc tatcttaaat tttcgatttt ttataaagcg ttttgtatta
     6241 tctaaataac tctttacaat ttactgattt ttaagctttt gctaatagat ttatgcaact
     6301 ttaatattat aagtaaatct atgcacttca tcattaaatt taaattctgc ccaaatttta
     6361 tacatccctt ttttaggaaa atgagcataa aaggttgtag aatcaggtga ttctgggtga
     6421 acatgaatat aatcagttaa ttgctcatca aatataatca catgtcctaa agctcctaaa
     6481 taaggttggg gagttaattc tgtattgaaa gttaaaggga catgttcatc ttctttagca
     6541 cttatagaat ttaaagttac atgaactcct ttgttaactt ttacccaatt tttatcagaa
     6601 tttaaagatg ttgtagaggt tattttatct ccaatttgca gttcaatagg atgaacggaa
     6661 tacacatggt tttttggtgt aacatcaaca aaagcctggt aagttcctgg ctctaattgt
     6721 tggttaatta taaataaacc ttcatgcttt ttttgagggt gtaggtggta atatttctcc
     6781 atgtcattag atactaaaac gaaatgcatt tctttttcat gcatagtatc taataatggg
     6841 gcattattaa attcatcttc taacgtaatt tctatattac catctctata tacaacattt
     6901 gctttaattt cgggtttgtt tgaatgatat tcatgattat gattcatatt tttatcctcc
     6961 ttaattttta ataagggcat atcattaaac gatatgccca actatttaaa ttatttaatt
     7021 acatcgtaac cttgatcttc aatagcttct ttaaagtcgt tgaaagctac ttgattttca
     7081 tcaaattcaa cttccacatt cccattcgcc aagcttactt ctgaagatgt tacaccatct
     7141 aatccattta atgctttttc aattgaatgc ttgcaatggt cacagctcat accttctaca
     7201 ttaataactt cgttagtcaa tgttgtcacc tcctttcaag aaatataaga ttcttataat
     7261 ttcatacgtt ttagacgtaa agcgtttgtg acaacactta cagaacttaa agccattgct
     7321 gctcccgcaa cccaaggtgc tagcagacca attgctgcta tagggatacc tgcaacattg
     7381 taaccaaacg cccaaaatag attttggcga atattacgaa ttgtagattt acttgctttt
     7441 attgcttttg gaattaataa aaggtctcct cctaaaatag ttatatcagc agcttcgatt
     7501 gcaacttctg tacctgtacc aatggcaata ccaatatctg ctttaactag tgctggagca
     7561 tcattgacac catctccaac catagctact tttttacctt cagattgaat ttctgctact
     7621 ttagaagctt tttcttctgg taaaacctct gcaataatcg tgtctatacc aacttgtttt
     7681 gctattgctt gtgcggtacg tttgttatca ccagttaaca tagcaacttc aatacctaat
     7741 tcatgaagtt tttgaatagc ttgttgggca gtatctttaa ctgtatcagc tacagcgaca
     7801 acccctctca attcgttatc tacgcttata agcattgcag tttttccttc tttttcaaat
     7861 tgagcgagat ttgtttcagc ttcattagtt tggattcctt tttcactcat tagttttcga
     7921 tttccgacaa aaagttcttt accatcaatt gttgcattta taccgcgccc tggtatagct
     7981 tcaaaatggt ctacttctaa aaattctaat gatttttctt tagcataact tacgatagct
     8041 tcagctagtg ggtgttcaga acctttttct gcactagcta acaattgtaa tgtttgatca
     8101 tctccactaa aatcagtgac ttcaggtgtg ccatttgtta tagtgccagt tttatctaaa
     8161 acaactgtat taatagcgtg tgtaccttca atgtgttctc cacctttaaa tagaatgcca
     8221 ttttcagcag cttttccggt acccaccatt atagaagtag gcgtagctaa gcctaacgca
     8281 caaggacaag cgataactaa tactgctatt gcagcaacta aggctggttc aaattgtccc
     8341 ggctgaacta atgaaatcca tataataaat gtgaaaatcg cgatacctac aacgataggt
     8401 acaaaatatc cagaaataat atctgctagt ctttgtattg gcgctttaga accttgcgct
     8461 tcttcgacaa ctttaacaat ggaggcaaga gctgtatctt taccaacttt tgttgcttca
     8521 acagtaattg ctccattttt attcattgtt gatcctataa cattatcatt ttgcattttt
     8581 tcaacaggaa tagattcacc tgtcaacatt gactcgtcaa ttgaagtcat acctttaatt
     8641 attttgccat ctactggtat tttttctcct ggtttgataa ctaaatagtc tccttctttt
     8701 acttcactta aaggaaccat agtctcttca ccgttgcgta atatacgtgc ttctttagct
     8761 tgtaaattca acaatttact taacgcattt gttgtttgtg ttttagcacg tgcttctaaa
     8821 tactttccga aaagaattaa agtaattaat acagcacttg tttcaaaata taggtgtggc
     8881 tcataatttg tattaattaa ccacttaatc gattcataaa tactataaaa gaaggctgcg
     8941 cttgtaccta aagcgacaag aacatccata tttgctgacc cattacgaag gtttttataa
     9001 gcgcctacat aaaattgcca accaataaca aattgaacag gcgttgctaa tacaaattgg
     9061 aaccacgggt tcataaatat atgtggtatt tgaataccaa ataaatgaac gaacattgtc
     9121 attaacaatg gagctgctaa aacagctgaa acaactaatt taattaactg tcgttttaat
     9181 tgtttttctt tttgggaact tttttctgat gcttcttttt taggttgtgc ctcataccct
     9241 aggtttttaa tacgttgttg aaattcatct acagacgtca tatcagggtt gtattctaca
     9301 gtagcacttt ctgtggttaa attaactgta gccttattta cacctgagat tcgatttaaa
     9361 actttttcga ttttattcga acaagctgca cacgtcattc ccattacatc gagatccact
     9421 ttttcggtta aaactccata acctgttttt tgaattgtat ttgcaatatc ttctaatgat
     9481 gtaacattgg ggttatattc aattgtagct ttctctgtag aaggatttac attagcgtta
     9541 acttcatcta atttatttag atttttttct actttattcg agcaagctgc acatgtcatg
     9601 cctgtgatac ctaatgaggt ttttttaata ttttcactca attatttctt tcctcctatt
     9661 ttgaaaattg ttttaataca accatcaatt ctttgatact ttcttctccg ttgccatttt
     9721 taataccttc acttacacaa ttagatatat ggtcttcagt tactataaaa cccacttgtt
     9781 ttagggctga ttgtattgct gttatttgta ctagtacgtc tatacaatat ctatcttctg
     9841 ctatcattga ttgtaaaccg cgcatttgtc cttctaatct tttgagtcta ttgagcaatg
     9901 cgtcattgtt tttaacagta gtagtgttca atttcacccc tcctcgtata ccctgatggg
     9961 gtatgtctta ttgaaaccta tattataccc ctggtaggta taagtcaata caaaagtttc
    10021 atataaaaaa ttaatattta tagtttgttt taagaggtac acttgtataa aatgtatgct
    10081 aaaacttata ttaggagaga tatatttgga taaaaatata caacttgagc tttacacaag
    10141 acctacatgc tctgattgcc aagaatcaaa aaggtattta aactctcaag agattagtta
    10201 tagtcataaa gatgtaagtc aaaatttgga cttagaagaa gaaatgaaaa aaatatcagg
    10261 caaccgaatt gttcccttat ttgtttttta taaaaaaaat ttttggggta aaaaaaagtt
    10321 gtttaaatat tacgtgggat ttgaaaataa caaaaaagat atattaaata tattggaata
    10381 attaaataaa cagccattat tttttaataa tggctgttta tttaatgatg atgttgactg
    10441 tctttttctt tcacgataca aaacaatttt tcactatgat tattgttaga agtttcagtc
    10501 tgtattgtga catgttgaat attttgatga ttgagttcat gttctatacg tttaagtaaa
    10561 aactcatttt cagtaatggt cattgtatct tctacaacaa tatgacaaga taacgcgttt
    10621 aatccgctag ttactgacca aacatgaaag tcatgaatat ttttaacttc tttgaatttt
    10681 ttaatagttt taataatgtc ttttgtattt atattgcttg gtgctccctc cattaataca
    10741 tgaagacttg attttgttac ataaaagccg ctacgtagta ctaaaattgc tacaatcaca
    10801 cttgctaaag gatccgccca cccccatcta aaaaatataa tgagaagggc tgctataact
    10861 gcacctatag atccaagcat gtcgcttatt acatgcaaat atgctccacg catatttaag
    10921 ttttcttcta catcgctccc gcgcagcatt atccaagcca caataatatt aataaacaag
    10981 cctaccaagg cgataattaa catgcctgta gaagctacct caggggggtt tttaaatctc
    11041 tcaatagctt cataaaaaat atagatagct attaacatca aagtaatacc attaagtaca
    11101 gctgctagta tttcaaacct tttgtagcca aaagttttat ttgtattagc ttgcttcgct
    11161 cctaaagtaa atgcaattaa agcaatacct aaagaaatag aatcacttaa catatgacca
    11221 gcatctgaaa ttaacgcaag actgttagta aagaaaccac ctaacccttc tacaatcatg
    11281 taacttgtaa taataataaa actaattaat aaagtctttt tgttcgcgcc atgtgtatga
    11341 ttatgattgt gatcgttttc catttaatcc ctcctctttt taatgatgaa aaatattttc
    11401 tataatttga atttttgttt ttataactat agagttaaaa aatataaaat ttcaattaat
    11461 gttttgttac tcgaagaaaa tcatactaac ttatgaatat atgctcatat attcataagt
    11521 tagtatgatt tttatccttt gtcaatatag aaatgctttg tattttgtat attaaataaa
    11581 aaccctactt tgctttggac agtagtggga tttttgcata tgataaacca cacttcactt
    11641 gctaaatatt aactatatta taattaacaa gtgataattt ctttttagag aaaataatgt
    11701 attcacgcct ttaggcgtga atacattatt tttttttgaa tagtttagaa aagatagatt
    11761 gtttttgttc attttttttt gaatagttta gaaaagatag attgtttttg ttcatttttt
    11821 tttgatgctt ttggagtaat gatatcttct tttgaatcta tattatcagt ttctattttt
    11881 ttggtattac ttaatatatt ttggctactt aaattcaaag attgttcttg ttttaatgca
    11941 attgttaaat cgtcaatttg tcgattcttt tgtcgttttt ttatttaaaa ttgtttttag
    12001 ataatctatt gtattatcat ctattaatga tttgttacct actttgttta ccttcaaatt
    12061 tgaaggtaaa ctttttaaat gataatgaat tgtttgttta gagacatcta aaagttcaga
    12121 aacttccttt acagttttca tcaaataact gggtctcctt tactttttca ttttttgtaa
    12181 aaacgcttga cgttcttctt ctgtatacgc agatgtctta gatgtggttg gttcataagt
    12241 gttatttttt aaccattgtg gcgtcatttc acggctggtt ctgttgcaaa gttaatttta
    12301 tagtataatt ttaacaaaaa aggagcgttc tctatgaatt attttagata taagcaattt
    12361 aataaagatg taataactgt agccgttggc tattacttaa gatacgcgct tagttatcgt
    12421 gatatatctg aaatactaag agaacgcggc gttaacgttc atcattcaac gatctaccgt
    12481 tgggttcaag aatatgctcc tattttgtat caaatttgga agaaaaagca taaaaaagct
    12541 tattataaat ggcgcgttga tgagacatac attaaaataa aaggaaaatg gtactattta
    12601 tatcgtgcca ttgatgcaga tggtcataca ttggatattt ggttacgtaa gaaacgagat
    12661 aatcattcag catatgcgtt tattaagcga cttattaaac aatttggtaa acctcaaatg
    12721 ataattacag accaggcacc ttcgacgaag gtggcaatgt ctaagttgat taaagatttt
    12781 aaacttaatc ccgactgtca ttgtacatct aaatatctta ataacctcat tgagcaggat
    12841 caccgtcata ttaaagtgag aaagacgaga tatcaaagcg tcaatacggc aaagaataca
    12901 ctcaaaggta ttgaatgtat ttatggtcta tataaaaaga accgtaggtc tcttcagatc
    12961 tacggatttt cgccgtgcta cgaaattaat cacatgttgg ccagttaagg gaatactacc
    13021 atgttaaaat gataattagt tatatttttt ctgactttgc aacagaacct aaatttaaat
    13081 atgagggcaa acttcaaaat atgttaccaa catttcatga tttattttat ggatttataa
    13141 cttttgatat tttaactttt ttattgctaa tatttatcac tatagattgg tatctcagaa
    13201 agaagaagta aatagtgttc agaaaacaaa ggtaatgaat agaaaaggtt ctgttgcaaa
    13261 gttgaattta tagtataatt ttaacaaaaa ggagtcttct gtatgaacta tttcagatat
    13321 aaacaattta acaaggatgt tatcactgta gccgttggct actatctaag atatgcattg
    13381 agttatcgtg atatatctga aatattaagg gaacgtggtg taaacgttca tcattcaacg
    13441 gtctaccgtt gggttcaaga atatgcccca attttatatc gaatttggaa gaaaaagcat
    13501 aaaaaagctt attacaaatg gcgtattgat gagacgtaca tcaaaataaa aggaaaatgg
    13561 agctatttat atcgtgccat tgatgcagag ggacatacat tagatatttg gttgcgtaag
    13621 caacgagata atcattcagc atatgcgttt atcaaacgtc tcattaaaca atttggtaaa
    13681 cctcaaaagg taattacaga tcagtcacct tcaacgaagg tagcaatggc taaagtaatt
    13741 aaagctttta aacttaaacc tgactgtcat tgtacatcga aatatctgaa taacctcatt
    13801 gagcaagatc accgtcatat taaagtaaga aagacaaggt atcaaagtat caatacagca
    13861 aagaatactt taaaaggtat tgaatgtatt tacgctctat ataaaaagaa ccgcaggtct
    13921 cttcagatct acggattttc gccatgccac gaaattagca tcatgctagc aagttaagcg
    13981 aacactgaca tgataaatta gtggttagct atatttttta ctttgcaaca gaaccgcatt
    14041 ttacacagga gtctggactt gactcacttc ctttattatt tttcattttt ttaaactatt
    14101 taatactaat gtcttttata atagcttttc atatattata taatcaatct ttataagtcc
    14161 ttttataaat ttcttttcta ccattttcga taaattcctg tttaatattt ttaattccat
    14221 aaacaatagt ttcaatagga taatattctt caactatatc ttgatattct tttgctttct
    14281 caatatctat atttccatac attcttaata tatcttctcc aaaatttgtt cctatttctt
    14341 cttcactatc ttcaagtaag tatataaaat cacaatattc atctataatt ccagaatctc
    14401 caaaatcaat tattccagtt aatctattat tgccatctaa caatagatga ttacaactaa
    14461 aatcattatg gcataaacac tttttaccct caaaaactgt tgttgcattt agtctttcca
    14521 taaaactttc tatataatct ttttctatat cagttaaatc attataaata gtttcacgca
    14581 acaatatata ctcttctaat acattttgtt tattatcaat agtacattca ctaatatctg
    14641 tataatctaa accgtgcatt tgtcttaaaa aactggcaat atctcgtttt aacaaatttt
    14701 gttcttcttc tgacatagta gaataaattt ctggtgttaa aaaagttcct ttaatttctt
    14761 tataacctag tatagataat tcatcactaa tatacgaata ttcaatatta ggaattttta
    14821 cattagtttc taaatttgta tttaaaaaat tatatattgc tttttctttt gcataacctt
    14881 ttttcttatt agtactaaat tttgttttaa aaatgtattc attattaact aaatatgcca
    14941 cactatcata accactaccg attatttcaa tactatctac tttgaaatta tcaaagtaat
    15001 gctcaattaa atatttcatt gccttaacat ttgtggcatt atcatcatat ctatattcca
    15061 ttaaataaca atcttctttt ttgccctcgt gtaattcatg ttctggcaaa tcttcaataa
    15121 ttctaaaacc agatttttgg tatgccctta ttgctcttgg attattttta tgagggtcta
    15181 aaataactgc attagcattt ctttcttttt tcaaaaattc aaaaatcaat ttaatatatc
    15241 ttgtaccaat tcctttactc caataatttg gctctcctat aaattgatcc ataccataga
    15301 ctatctcatc agtttttgga taatgataat cagtatataa ctcatcatac attttatata
    15361 tttgtccata tccaatagga acattgttat attcaataat tactctaaaa acttcatctt
    15421 cccaaggctc tgtataatgt ttttttaatg attctaatgt atatttttta tctctaccac
    15481 cataaaattc taatactctt tcatcagtta accattttaa catcaaagga aaatcatcat
    15541 ctattaaagt tcttatacat atttcatttt caactatatt catttattta tcaccttttt
    15601 cataatcata tacatatact atttcatctt ggttctgttg caaagttgaa tttatagtat
    15661 aattttaaca aaaaggagtc ttctgtatga actatttcag atataaacaa tttaacaagg
    15721 atgttatcac tgtagccgtt ggctactatc taagatatgc attgagttat cgtgatatat
    15781 ctgaaatatt aagggaacgt ggtgtaaacg ttcatcattc aacggtctac cgttgggttc
    15841 aagaatatgc cccaatttta tatcgaattt ggaagaaaaa gcataaaaaa gcttattaca
    15901 aatggcgtat tgatgagacg tacatcaaaa taaaaggaaa atggagctat ttatatcgtg
    15961 ccattgatgc agagggacat acattagata tttggttgcg taagcaacga gataatcatt
    16021 cagcatatgc gtttatcaaa cgtctcatta aacaatttgg taaacctcaa aaggtaatta
    16081 cagatcagtc accttcaacg aaggtagcaa tggctaaagt aattaaagct tttaaactta
    16141 aacctgactg tcattgtaca tcgaaatatc tgaataacct cattgagcaa gatcaccgtc
    16201 atattaaagt aagaaagaca aggtatcaaa gtatcaatac agcaaagaat actttaaaag
    16261 gtattgaatg tatttacgct ctatataaaa agaaccgcag gtctcttcag atctacggat
    16321 tttcgccatg ccacgaaatt agcatcatgc tagcaagtta agcgaacact gacatgataa
    16381 attagtggtt agctatattt tttactttgc aacagaaccg atattaatac atttgaagtg
    16441 atttccaacg ctatattaaa tatgaaaaga ttatagaaag cattgaatta tcggttagtc
    16501 gatagtaact atctttttaa gataagaagt gataacgatc attatgtaaa caaaattaag
    16561 gagtgtatat tatgaatacg ttgaacacag taatgttatg tataggttta ttctttgtaa
    16621 taccttcaat gatatattta actatttatt atattgttaa tacaattgtt ttatatcaaa
    16681 aatcaaaaac taaaaccagt atttccacaa atatatatgg tgtaaaagaa attaaataca
    16741 atgtgtctcc acgcctatta agaatacaga caaaactcaa agaaaataga gtgtttgggg
    16801 ctattggatt tgtttttgga ttatttatga ttgatattcc tttattatat atattgctag
    16861 aatttttaaa agatttctta ccttctctat cattttaaat agagtattca atttcataaa
    16921 aaaagagatt aggtttgtaa tttacttgta tatagcattg gtaggtatgt atgttttaat
    16981 ggaaagaatg tttaagtaca atatttttcc tgcaaattta aaaaatatta atcaaatatt
    17041 atctataata catgatataa atacaaacca gtttatttca ctaatatatt tattaatgat
    17101 ttgtatttat gtaatgttct ttttacctta tcgcttatta aaactttaca atgagataat
    17161 aaaagatacc aatagtaaag attatataca ttcttttatt gttactaact tcaataaaat
    17221 tgaaaaaaat caaaaacaaa aaagtaacaa tatcatagca ataataatgt atttttaaat
    17281 tgaatatgac tgattagggt aaaccctaat catacaaaga gagttattga atttataata
    17341 acttaaacgt atgattaggg tgtatattaa ttgtggagtg aaaatgaatg attataggtt
    17401 atgcaagagt atcttcggta gatcagaatt tagagagaca gctagataat ttgaaaacat
    17461 ttggcgtaga gaaaatattt acagagaaac aatcgggaaa gtcagtagaa aatagacccg
    17521 tatttcaaga agcacttaac tttgtgagaa tgggcgatag atttgtagta gaatcgattg
    17581 atcgcttagg tcgtaattat gatgaagtga ttaacacagt taattattta aaggataaag
    17641 aagttcaatt gatgattact agtttaccta tgatgaatga agtgattggt aatccactat
    17701 tagataaatt tatgaaagat ttaatcgttc aaatcttagc aatggtttca gaacaagaac
    17761 gaaatgaaag taaacgtaga caagcacaag gtattcaagt tgcgaaagaa aaaggtgtgt
    17821 ataaaggacg ccctttacta tattcaccta atgctaaaga tcctcaaaaa cgtattatct
    17881 accatcgtgt tgttgaaatg ttagaagaag gcaaagcaat tagtaagatt gcgaaagagg
    17941 ttaatatcac aagacagaca gtttatagaa ttaaaaatgg taagggatta tcttgataaa
    18001 tggattgtta atgcaaatga gatcttctca cagcgtccta aattatatgt tattcatcta
    18061 ttatgagatt ctaataataa gacaagaaaa gagagtgcga attcgcactc tccttttgtg
    18121 tagtactatt gaaattttgt cttaaaaacg aacgtaattt agaaataata tttattggta
    18181 tttcaagaat atatatataa ttatttacta agtccattta aaaaaatttg agagaacttg
    18241 ttcataagtt taattctttc attaatattt tgttcatgtg taaaggtaac aattccatta
    18301 acagcgtttg ctgctatttt actaacagca ttaacatcat taatacacca ttcgccattt
    18361 aaattaccct ccttaaaaat tacatgataa gcatctatat atttgttttc taatttattc
    18421 attttttcat taatgctatt agttttataa tattcagtgc aaaattcaat tattgcgttt
    18481 tgaagtggat aatagtattc ggttgttaaa gatagttcat tatataaata aaatttttct
    18541 ctattagttt tacatttgat ttgttccttt ttccactgtt cttgccattt agattcttct
    18601 atatttaaaa tttctaaaaa tagattttct tttgttttaa agtgataata aagattccct
    18661 ttactacttt ctgataattt aacaatttct ccagtagtag tggcattata tccatttttt
    18721 ataaataatt cctttgcgac acctagtatt ttatctttca agttcatcac gcctttaatg
    18781 agtattaagt actatcaatg atagcacaaa aaattcaaag aataattgta taacacaata
    18841 cagccattta aatttcgcaa gattttttgt tgtaatatgt aaaaaaatag attacaatcc
    18901 ttatagaccg atcgcacggt ctataaggat tggagggaac ttaaatgatt tcatttttta
    18961 caaaaactac tgatatgatg acatcaaaaa aaagatggac tgcactagta gtattagctg
    19021 ttagtttgtt tgttgttaca atggatatga caatattaat tatggcttta ccggaattag
    19081 taagagagtt agagccttct ggtacccaac agttatggat agttgatata tactctcttg
    19141 ttttagctgg ctttataatt ccattgagtg cctttgctga taaatgggga agaaaaaaag
    19201 cattattaac tggatttgct ttatttggcc tcgtttcatt agctatattt ttcgcagaaa
    19261 gtgcagagtt cgtaatagct attcgatttt tacttggtat tgcaggtgct ttaataatgc
    19321 caactactct ttcaatgata agagtaattt ttgaaaaccc taaagaaagg gccactgcat
    19381 tagctgtatg gtcaatcgct tcatcgatag gtgctgtttt tggaccaatt atcggaggag
    19441 ctttacttga gcaattttca tggcactcgg catttttaat taatgtaccg tttgcgataa
    19501 tagcagttgt agcaggttta tttttattac cagagtctaa gttatcaaaa gaaaagtctc
    19561 actcgtggga tattccttct acaattttat caattgcagg catgattgga ctggtatgga
    19621 gtatcaaaga attttcaaaa gaaggactag cagatattat tccatgggtt gtaatagtat
    19681 tagcaattac catgatagtg atatttgtta aacgtaattt atcaagttct gatccaatgt
    19741 tagacgtaag actttttaaa aagagatcat tttcagctgg tacaattgct gcatttatga
    19801 caatgtttgc aatggcatct gttttgttat tagcttcaca atggttacag gttgtggaag
    19861 aactttctcc ttttaaagct ggcttatacc tattacctat ggcaatagga gatatggtgt
    19921 ttgcaccaat tgcacccgga ttagcggcgc gatttggacc gaaaatagtg ttaccttccg
    19981 gaattggaat tgcagccatt ggcatgttta ttatgtattt ctttggtcat ccattatcat
    20041 attctacaat ggctttagca ttaattttag ttggagctgg tatggcttca ctagcagttg
    20101 catctgctct aataatgtta gaaacaccta catcaaaagc aggtaatgca gctgctgttg
    20161 aagagtctat gtatgacctt ggaaatgttt ttggtgtagc agtacttggt agcctatctt
    20221 ctatgcttta tcgtgtattt ttagatattt catctttttc atcaaaaggt atagttggag
    20281 atttagctca tgtagctgaa gaatctgtag tgggcgctgt cgaagtagct aaagctacgg
    20341 ggataaaaca gcttgcaaac gaggctgtaa catcatttaa tgatgctttt gtagcaactg
    20401 ctttagtagg tgggattatc atgattatca tttcaatagt tgtctatttg ttaattccca
    20461 aatcacttga tataactaaa caaaaatagt actaaacata tatttttaga tattgtagat
    20521 tagtttattt ttaaaattag taatagttaa aaagtagaac cattaatttt aaatggttct
    20581 acttttttat tattaagtaa aattataaaa gacaatttct taaattaata atatgatata
    20641 cctatatcta ataatttatt agtattaata aaccttgaaa ggatgattaa ctgatgaata
    20701 gagcagatat ttttaaaata tttgatgtag aacttaatat aactatattt ttaggagcac
    20761 tagtagcaac tttcatctat tttataagtt acatgaacaa tgtaaatgaa ttaattacat
    20821 tatgcttaac attagctttt cctgcatatt tattaaaaat tagcagatcg ttcgaggtta
    20881 ttttattaga ggaaaaaata aaaaatagta aaatcaaaat ctgtgacaaa gatagaattg
    20941 aacgagagat actggtgaaa aagaacctaa tagatgaact attgtttcct aatagagtta
    21001 ttaaaaaata tacactgaca attttaattt acagtatagg tattattatt cttttactac
    21061 tttgtaatat gttaagttat ggaattggtg aaaatgtcaa ttttatctgg agattactag
    21121 cttgttatgt aacgagtgtc acagtgatta tagttgcctt gattataatg ataatgatat
    21181 ttgatcttat aattggatta ctattaaatt ttcaaatatt tttaaaaaat aaaaagtatg
    21241 atgacttttt ataattattc gatttatata atgaaaaatt aaatgattaa acatagaaac
    21301 ctcaaaacaa accatattta atagagttta tggcgcctta tacaaataaa ggctatgctg
    21361 ttaaagaatt atgtagctat cttcagatta atatggatga tgtttatact attggcgata
    21421 gaaaattgat ttacctatgt ttaataccct agataattct tctgataatt tagtttttgt
    21481 tagagtttaa cataactgat gattatcaga agttccatca ctataaaagg tgtatcaagg
    21541 gtttataaac tcttgataca ccttttatag tcatttttaa ttaccaaaca gtttactcca
    21601 aaaacttttt ttagaatgat tttcgtttct gatatcctct ttctgctcac catctatttt
    21661 attaccttgt tgcttatcct catgtttatc tttactttca tccctaaaat gggaaaccat
    21721 tttttctttt tgactatctg agtcattatt tatagaatcc atattttcca ttgtttcttg
    21781 aacttcaatg tcctgcctct tattagcaga ataattgagt tgcctttctt cttctaactc
    21841 agactccaaa ctttgtattt ttttgttact ttctaatgct aatacttgtt ggttttcaag
    21901 taatttcgac ctttcttgta attcttttct ataaaattct attgtcgttt catgacgttt
    21961 ttcttgtttt tcaagttgtt tatttaaagt atctatttgc ttttcgagta gttcaattat
    22021 ttgaacatca tatttagatt cgtttttttt attatctgtt ttaactttct ctgaacttac
    22081 attagcactt tcaaagccat atttcttttt atttctgatt actctttgaa tgattttttc
    22141 tacatcaaca tcatttttaa tgaatgaagt attatcctgt ttcactgttt ctatattcaa
    22201 tctttttata ttattaaata cagtctgttt actaacttcc aattcttcac ttatttcttt
    22261 aacgctcttc atatcttcaa ccctttataa atactttatc aaccctttat aaataaattt
    22321 tatcacaaat acttttataa agggatctta agtagtatta aaaaaccttt tataaacact
    22381 tgataagatt attatcaagt gtttataaaa ggtttttagt gggattataa tatcttttat
    22441 atgttctttt ttaatgatat aatgtccata atacgtttta gtcccaacta ctggtaatag
    22501 ttgggactgg gtaataaaac gttacaatac gttagctatt taatttgata tatgtattat
    22561 atacaacaat atctacagt
//
