LOCUS       NZ_CP097025            23514 bp    DNA     circular CON 19-MAY-2024
DEFINITION  Enterococcus faecium strain AT45b plasmid pAT45b-c, complete
            sequence.
ACCESSION   NZ_CP097025
VERSION     NZ_CP097025.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN28025462
            Assembly: GCF_023299725.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23514)
  AUTHORS   Biggel,M.
  TITLE     Florfenicol-resistant Enterococci from pet food
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 23514)
  AUTHORS   Biggel,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-MAY-2022) Institute for Food Safety and Hygiene,
            University of Zurich, Winterthurerstrasse 272, Zurich 8057,
            Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.5.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x, 100x
            Sequencing Technology :: Illumina MiniSeq, Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023299725.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:48:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,899
            CDSs (total)                      :: 2,806
            Genes (coding)                    :: 2,683
            CDSs (with protein)               :: 2,683
            Genes (RNA)                       :: 93
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 123
            CDSs (without protein)            :: 123
            Pseudo Genes (ambiguous residues) :: 0 of 123
            Pseudo Genes (frameshifted)       :: 43 of 123
            Pseudo Genes (incomplete)         :: 75 of 123
            Pseudo Genes (internal stop)      :: 32 of 123
            Pseudo Genes (multiple problems)  :: 21 of 123
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP097025.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..23514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="AT45b"
                     /isolation_source="pet food (BARF)"
                     /db_xref="taxon:1352"
                     /plasmid="pAT45b-c"
                     /collection_date="2022"
                     /collected_by="ILS, University of Zurich"
     gene            1..1041
                     /locus_tag="M2917_RS14140"
                     /old_locus_tag="M2917_14140"
     CDS             1..1041
                     /locus_tag="M2917_RS14140"
                     /old_locus_tag="M2917_14140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_000997689.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLLK
                     DRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGRVN
                     KRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTTVIA
                     KIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVDIMKE
                     DSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELESYGIDA
                     DKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFNELPTVS
                     TENWLE"
                     /name="replication initiator protein A"
     gene            complement(1657..2337)
                     /locus_tag="M2917_RS14145"
                     /old_locus_tag="M2917_14145"
     CDS             complement(1657..2337)
                     /locus_tag="M2917_RS14145"
                     /old_locus_tag="M2917_14145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(<2412..2777)
                     /locus_tag="M2917_RS14150"
                     /old_locus_tag="M2917_14150"
                     /pseudo=""
     CDS             complement(<2412..2777)
                     /locus_tag="M2917_RS14150"
                     /old_locus_tag="M2917_14150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366464.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(2759..3157)
                     /gene="mobC"
                     /locus_tag="M2917_RS14155"
                     /old_locus_tag="M2917_14155"
     CDS             complement(2759..3157)
                     /gene="mobC"
                     /locus_tag="M2917_RS14155"
                     /old_locus_tag="M2917_14155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="WP_002340414.1"
                     /translation="MSEHDNNLASDLSVGGNRKPNRKEPKQISFRVNEGEYEKLRSSAE
                     TLNMSVPTFVKKKAQGSRLVAPKLDKETRQSIVKDLGSMGANVNQIAKWFNQHKEQAVN
                     LPEQKYDDLIKQFDDFKKELHEIWQQLK"
                     /name="mobC"
     gene            complement(3472..4119)
                     /locus_tag="M2917_RS14160"
                     /old_locus_tag="M2917_14160"
     CDS             complement(3472..4119)
                     /locus_tag="M2917_RS14160"
                     /old_locus_tag="M2917_14160"
                     /EC_number="2.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-8 chloramphenicol O-acetyltransferase"
                     /protein_id="WP_000143686.1"
                     /translation="MTFNIINLETWDRKEYFNHYFNQQTTYSVTKELDITLLKSMIKDK
                     GYELYPALIHAIVSVINRNKVFRTGINSEGNLGYWDKLEPLYTVFNKETEKFSNIWTES
                     NASFNSFYNSYKNDLFKYKDKNEMFPKKPIPENTVPISMIPWIDFSSFNLNIGNNSRFL
                     LPIITIGKFYSKDDKIYLPFSLQVHHAVCDGYHVSLFMNEFQNIIDNVNEWI"
                     /name="type A-8 chloramphenicol O-acetyltransferase"
     gene            complement(4276..4956)
                     /locus_tag="M2917_RS14165"
                     /old_locus_tag="M2917_14165"
     CDS             complement(4276..4956)
                     /locus_tag="M2917_RS14165"
                     /old_locus_tag="M2917_14165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            <5031..5219
                     /locus_tag="M2917_RS14170"
                     /old_locus_tag="M2917_14170"
                     /pseudo=""
     CDS             <5031..5219
                     /locus_tag="M2917_RS14170"
                     /old_locus_tag="M2917_14170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase C-terminal repeat-containing
                     protein"
                     /name="topoisomerase C-terminal repeat-containing protein"
     gene            5353..5594
                     /locus_tag="M2917_RS14460"
                     /old_locus_tag="M2917_14175"
                     /pseudo=""
     CDS             5353..5594
                     /locus_tag="M2917_RS14460"
                     /old_locus_tag="M2917_14175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425012.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /name="peptide-binding protein"
     gene            5643..5726
                     /locus_tag="M2917_RS14180"
                     /old_locus_tag="M2917_14180"
     CDS             5643..5726
                     /locus_tag="M2917_RS14180"
                     /old_locus_tag="M2917_14180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]; GO:0031556 - transcriptional attenuation by ribosome
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="WP_001814874.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
                     /name="23S rRNA methyltransferase attenuation leader
                     peptide"
     gene            5851..6588
                     /gene="erm(B)"
                     /locus_tag="M2917_RS14185"
                     /old_locus_tag="M2917_14185"
     ARG             5852..6585
                     /name="erm(B)"
                     /gene="erm(B)"
                     /gene_name="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE/MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            <6758..7018
                     /locus_tag="M2917_RS14190"
                     /old_locus_tag="M2917_14190"
                     /pseudo=""
     CDS             <6758..7018
                     /locus_tag="M2917_RS14190"
                     /old_locus_tag="M2917_14190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /GO_component="GO:0005694 - chromosome [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /name="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            complement(7175..8470)
                     /locus_tag="M2917_RS14195"
                     /old_locus_tag="M2917_14195"
     CDS             complement(7175..8470)
                     /locus_tag="M2917_RS14195"
                     /old_locus_tag="M2917_14195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="WP_002297218.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRAC
                     RSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQSY
                     FVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSKKIL
                     PRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEEVEFL
                     VTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKSQAEKL
                     KKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAYPFFHEL
                     VEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNGKIEAKNT
                     HIKTMKRVSYGFKSFENMRIRIFLINQLINVR"
                     /name="ISL3-like element ISEfa11 family transposase"
     gene            8703..>9368
                     /locus_tag="M2917_RS14200"
                     /old_locus_tag="M2917_14200"
                     /pseudo=""
     CDS             8703..>9368
                     /locus_tag="M2917_RS14200"
                     /old_locus_tag="M2917_14200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
                     /name="IS1182-like element IS1182 family transposase"
     gene            9404..9649
                     /locus_tag="M2917_RS14205"
                     /old_locus_tag="M2917_14205"
     CDS             9404..9649
                     /locus_tag="M2917_RS14205"
                     /old_locus_tag="M2917_14205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_000567888.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRLL
                     LGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
                     /name="single-stranded DNA-binding protein"
     gene            9752..10621
                     /locus_tag="M2917_RS14210"
                     /old_locus_tag="M2917_14210"
     CDS             9752..10621
                     /locus_tag="M2917_RS14210"
                     /old_locus_tag="M2917_14210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /protein_id="WP_000228166.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIYY
                     NSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIKRV
                     EQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETYPNA
                     LQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYCINEK
                     KAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINNFLNEE
                     SSDERKQI"
                     /name="nucleotidyltransferase domain-containing protein"
     gene            10602..11336
                     /locus_tag="M2917_RS14215"
                     /old_locus_tag="M2917_14215"
     CDS             10602..11336
                     /locus_tag="M2917_RS14215"
                     /old_locus_tag="M2917_14215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]; GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_000662263.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGKR
                     VLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDFPE
                     ESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNEKGE
                     ILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPENMMD
                     IPGMADEMRRPMMLIVSAKKKM"
                     /name="class I SAM-dependent methyltransferase"
     gene            11369..12277
                     /locus_tag="M2917_RS14220"
                     /old_locus_tag="M2917_14220"
     CDS             11369..12277
                     /locus_tag="M2917_RS14220"
                     /old_locus_tag="M2917_14220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="WP_001255866.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYDI
                     TYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLTLL
                     PLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNVTPY
                     VIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYISEDLW
                     EKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRDMYKKY
                     TGKTGCLDSTYAADIEERREQ"
                     /name="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
     gene            12274..12816
                     /gene="sat4"
                     /locus_tag="M2917_RS14225"
                     /old_locus_tag="M2917_14225"
     ARG             12275..12813
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            12909..13703
                     /gene="aph(3')-IIIa"
                     /locus_tag="M2917_RS14230"
                     /old_locus_tag="M2917_14230"
     ARG             12910..13700
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(14088..14768)
                     /locus_tag="M2917_RS14235"
                     /old_locus_tag="M2917_14235"
     CDS             complement(14088..14768)
                     /locus_tag="M2917_RS14235"
                     /old_locus_tag="M2917_14235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            14830..15525
                     /locus_tag="M2917_RS14240"
                     /old_locus_tag="M2917_14240"
     CDS             14830..15525
                     /locus_tag="M2917_RS14240"
                     /old_locus_tag="M2917_14240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002326819.1"
                     /translation="MQQNPTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFIQRVEE
                     QLYLESETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETEKYIMNVYLERSELVENF
                     VSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATIDDYYLVFTRFLTCGTESIV
                     LMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRKRMPY
                     QRFERKKRQ"
                     /name="hypothetical protein"
     gene            complement(15572..15808)
                     /locus_tag="M2917_RS14570"
     CDS             complement(15572..15808)
                     /locus_tag="M2917_RS14570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_306297428.1"
                     /translation="MKQNTSIAKNTTKFKCTAAAWRISISPTNRTNNRGMILFIWISFF
                     LLGYRVLPAYFAPPKRRGRLERLVRNKNHSLSY"
                     /name="hypothetical protein"
     gene            15906..16085
                     /locus_tag="M2917_RS14250"
                     /old_locus_tag="M2917_14250"
     CDS             15906..16085
                     /locus_tag="M2917_RS14250"
                     /old_locus_tag="M2917_14250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001120991.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLLI
                     AQEKAGFEVPALKK"
                     /name="hypothetical protein"
     gene            16216..16485
                     /locus_tag="M2917_RS14255"
                     /old_locus_tag="M2917_14255"
     CDS             16216..16485
                     /locus_tag="M2917_RS14255"
                     /old_locus_tag="M2917_14255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /GO_component="GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="WP_000388479.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKRD
                     YDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
                     /name="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
     gene            16478..16735
                     /locus_tag="M2917_RS14260"
                     /old_locus_tag="M2917_14260"
     CDS             16478..16735
                     /locus_tag="M2917_RS14260"
                     /old_locus_tag="M2917_14260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /GO_process="GO:0008219 - cell death [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="WP_000588503.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLGK
                     PEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
                     /name="Txe/YoeB family addiction module toxin"
     gene            17194..18198
                     /locus_tag="M2917_RS14265"
                     /old_locus_tag="M2917_14265"
     CDS             17194..18198
                     /locus_tag="M2917_RS14265"
                     /old_locus_tag="M2917_14265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000455809.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINVF
                     FYSKEKLADFSNIAEMIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACEI
                     GVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRNKL
                     VHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQITL
                     SKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
                     /name="hypothetical protein"
     gene            complement(18363..18977)
                     /locus_tag="M2917_RS14270"
                     /old_locus_tag="M2917_14270"
     CDS             complement(18363..18977)
                     /locus_tag="M2917_RS14270"
                     /old_locus_tag="M2917_14270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001261742.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRPV
                     FQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGNPL
                     LDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQRRL
                     VYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
                     /name="recombinase family protein"
     gene            19427..20752
                     /locus_tag="M2917_RS14275"
                     /old_locus_tag="M2917_14275"
     CDS             19427..20752
                     /locus_tag="M2917_RS14275"
                     /old_locus_tag="M2917_14275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="WP_000969590.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRAD
                     NTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNIFR
                     RYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIATVG
                     VGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRLNQMG
                     IMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQVLPRD
                     YTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKIPITDNT
                     KELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEENLDKIIDK
                     IRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
                     /name="Y-family DNA polymerase"
     gene            20745..21095
                     /locus_tag="M2917_RS14280"
                     /old_locus_tag="M2917_14280"
     CDS             20745..21095
                     /locus_tag="M2917_RS14280"
                     /old_locus_tag="M2917_14280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000568378.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTEE
                     IAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIRHI
                     EFYQDNKWSRLE"
                     /name="hypothetical protein"
     gene            21092..21271
                     /locus_tag="M2917_RS14285"
                     /old_locus_tag="M2917_14285"
     CDS             21092..21271
                     /locus_tag="M2917_RS14285"
                     /old_locus_tag="M2917_14285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001021554.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAAA
                     GYHNFRFYIFPLYI"
                     /name="hypothetical protein"
     gene            21407..21697
                     /locus_tag="M2917_RS14290"
                     /old_locus_tag="M2917_14290"
     CDS             21407..21697
                     /locus_tag="M2917_RS14290"
                     /old_locus_tag="M2917_14290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000026576.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITRQ
                     RRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
                     /name="hypothetical protein"
     gene            22065..22853
                     /locus_tag="M2917_RS14295"
                     /old_locus_tag="M2917_14295"
     CDS             22065..22853
                     /locus_tag="M2917_RS14295"
                     /old_locus_tag="M2917_14295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /GO_process="GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000101106.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQGN
                     ATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVGSE
                     HRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKLSET
                     IETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRRTITVD
                     EAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
                     /name="AAA family ATPase"
     gene            22840..23166
                     /locus_tag="M2917_RS14300"
                     /old_locus_tag="M2917_14300"
     CDS             22840..23166
                     /locus_tag="M2917_RS14300"
                     /old_locus_tag="M2917_14300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000796719.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKDQ
                     GSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLAKK
                     QNKI"
                     /name="hypothetical protein"
     ARG             11370..12274
                     /name="ant(6)-Ia"
                     /gene="ant(6)-Ia"
                     /gene_name="aminoglycoside nucleotidyltransferase
                     ANT(6)-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(3476..4119)
                     /name="catA"
                     /gene="catA"
                     /gene_name="type A-8 chloramphenicol O-acetyltransferase"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             5852..6588
                     /name="ErmB"
                     /gene="ErmB"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="98.37"
                     /coverage="98.79"
     ARG             complement(3473..4119)
                     /name="Enterococcus faecium chloramphenicol
                     acetyltransferase"
                     /gene="Enterococcus faecium chloramphenicol
                     acetyltransferase"
                     /gene_name="chloramphenicol acetyltransferase (CAT)"
                     /tool="rgi"
                     /drug_class="phenicol antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             12275..12816
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="99.44"
                     /coverage="100.0"
     ARG             11370..12277
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="109.42"
     Typing          3148..3364
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="82.511"
                     /coverage="92.0"
                     /evalue="5.02e-45"
     Typing          2..1041
                     /name="rep_cluster_889"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(2428..2738)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="85.577"
                     /coverage="81.0"
                     /evalue="1.5000000000000002e-56"
ORIGIN
        1 atgaatgatt ttaattatta caaatcaaaa gaaatttatc gtgaaaaata ttatcaaatg
       61 cctaaggtat tttttactaa cgaaaaatac atggatctat caaatgatgc aaaaattgct
      121 tatatgctac ttaaagatcg atttgattat tcagtcaaaa ataactgggt agattctgat
      181 gataatatat ttttcatatt cacagttgaa gaattaatga aattgttaca atgccgcgaa
      241 ggtaaagtat ctaaaatcaa aaaggaatta gaaaaagcag gtcttctgaa acagaagaga
      301 ggaagagtaa ataaacgtga cggtaagatt gaatccatgc ctaatttatt gtacttaggc
      361 aagccagaag taacgaatca agacgtcttt aaaatcatgg aagaggaaga caatactgat
      421 accaccgtaa ttgcgaaaat cgcaaatacg gcaaaaccgc gagaaatcaa tgataccacc
      481 gtaattgcga aaatcgcaaa tacggcaaaa tccagtcata tcaaggactc aaccgtaatt
      541 gcgaaaatcg cagacaatct attctattct aattctatag acactaatag acacataata
      601 gacactgaaa ctgatcagtt acaaaatcaa gttttactag ataacttcgt cgacatcatg
      661 aaagaggaca gtataaatac atttgtacca gaaaatgtat taaacttgat aaaaacattt
      721 tctagtactt acgaagacgc tcaaaaaacc gtccaaacta ttcataatgc aaagaaaaaa
      781 gctgaagaat tagagcaaac agttgttgtt tatgaagaac tggaatctta tggaattgat
      841 gctgacaaag gattatatat gactttgctg aaagcttatc aaaaacaaaa aactgaaaaa
      901 gtaaacaatt tgcagaatct aattttcgtt tatgtaaaaa attggtttgt cgaaaaagct
      961 attgcggcaa agcttgcaaa cgaacaaaga gaaacattta acgaattacc aacagttagt
     1021 acggaaaatt ggctagagta gttgataaaa agcgatcact ataaaaatga tcaattttaa
     1081 attagaactt ttttatgatt ttaattttat tacaaatgtt acaaataaat agctattatt
     1141 ccggagtttt tagattaaaa gtttatgaaa acaatcacaa acgtaggttt taaagtcata
     1201 atcgttagat attttagtta tttttcattc aaaaaaatag ggaactagtg tttgcatatg
     1261 tgcttttttg agttataata attcatgaag agaggtaatt cacttatttc cccaagctga
     1321 aaagcctgat attacttctt ttcaggcagt gctgctaata ttcaattaca cttttttgta
     1381 tatttttagt tgttttaaat ttaattgtct gatatgcttg tgatgaattg attttcgttc
     1441 tgcacttttg gacgataaat tgtgataatt gaaaatacaa aaaaaagaaa ggcccctgta
     1501 aggctcggga gactggtaat ctccgtcagt gtcctacagg aaagcattaa gatgacgcct
     1561 taatgcgtgc ccttcagtgt tacggtatta cccgcaacgg acggttctgt tgcaaagttt
     1621 taaataaaga ataaaatccc ttacggtatc tatgatttaa gctgggattc ccaataatac
     1681 cttgatttca gtacagaccg aaaacccgaa gagagtgcct tcttttcggg ttttcttata
     1741 taatcctcga atggcttcca tgcctttaat cgtggtagag gcagtgcgta aacttcgata
     1801 gaatttattg cgtctcttta ctggacgatg gtcttgttca atcaaattat tcaggtattt
     1861 aatggtacga tgttctgtcc cttgataaaa gccgtattct tttagtttct taaaggcact
     1921 tgtaatagag ggggctttat ctgtgactac aaccttcggt tcatcaaact gcttcactaa
     1981 ccgcttaaga aaagcatagg ctgcttgtgt gtcccgtttt ttacgtaacc aaatatccaa
     2041 ggttaaacca tctgcatcga tggctcgata caaataatgc cattttcctt taattttgat
     2101 gtacgtttca tccattttcc atgaataaaa ggatttttta tttttctttt tccaaatttg
     2161 atagagtagt ttgccatatt cttgcaccca acgataaatc gtcgtatgag aaacgttaat
     2221 gccacgatca tataagattt cttgaacttc acgatagcta aggttataac gaagatagta
     2281 gcccacggct acaataatca catcctgctg aaattgcttt cctttaaaat gattcatcgt
     2341 cattcctcct gctatctttt tctattattc taccttattt gatagtagat ttaaaacttt
     2401 gcaacagaac cttttttatt attattaaat ttcttccccg tttctaaatc aattgaatta
     2461 atcacaatat gattatgaac atggtctgtg tcgttatgcg tatatacggc aacttgatga
     2521 ttaggtgcta tcttttcggc taattctaag cctaattgat tacattgttc tggcgttact
     2581 tcgttaggtt taaaagactg aataaccaca tgtccttcgt tgccatctgt tttgccatac
     2641 atttcacgtg ttgctttaaa actgcttttt gcataatcta tatcgcaatt caaagcgctt
     2701 ttttcttctg cccgtttctc tgcgtaatta atagcccttg atgttgattt tgttgagctt
     2761 attttagttg ttgccatatc tcatgcaact cctttttaaa gtcatcaaat tgcttaatta
     2821 aatcatcgta tttttgttca ggtaaattca ctgcttgttc tttatgttga ttaaaccatt
     2881 tcgcaatctg atttacgttt gcccccatac tgcctaaatc tttaacaatc gattgtcgcg
     2941 tctctttatc taatttgggc gctaccaatc gactgccttg tgcctttttc ttaacgaaag
     3001 tcggcacact catattcaaa gtttcggcag atgaccttaa cttttcatat tcgccttcgt
     3061 tcactctgaa actaatttgt tttggctctt tgcggttggg tttacggttt cccccaacag
     3121 acaaatcgct agccaaatta ttatcatgtt cactcattca atcccaccac gtttcttcga
     3181 aatttattac tctctatgtt tgtagattat aggataatca acaaaatatc aagtaataat
     3241 gtggtttggc aagcactggc tttgctatcc acttcgttct agcacgccgt acttgatggg
     3301 attatatccc atacccttta tgtttttgct tacgcaaaaa atgagtggca aaatgctagc
     3361 cactcatagt tcaaaaccaa attcaaaatc aaaacaaaag caaccaaaaa tgtggttgct
     3421 ataaacttat aaatatcatg attacttaag tttatgaaat ttattttaga tttaaatcca
     3481 ttcatttaca ttatcaatta tattttgaaa ttcattcata aataatgaaa catggtaacc
     3541 atcacatact gcatgatgaa cttgcaatga aaatggtaaa tagatcttat catccttact
     3601 ataaaattta cctattgtaa taattggcaa taaaaatcta ctattattac caatatttaa
     3661 attaaatgaa ctaaaatcaa tccaaggaat catcgagata ggaactgtgt tttcaggtat
     3721 cggcttttta ggaaacattt catttttatc tttatattta aataaatcat tcttataact
     3781 attataaaaa gagttaaaac tagcatttga ttctgtccaa atattagaaa atttttcagt
     3841 ttctttatta aagactgtat ataaaggttc taatttatcc caataaccca aattcccctc
     3901 actattaatc cctgttctaa atactttatt tcgatttata acacttacaa ttgcatgaat
     3961 caaagcagga tacagttcat atcctttatc ttttatcata ctttttaaca aggtaatatc
     4021 taattcttta gtaacactat aagttgtttg ttgattaaaa taatgattga aatattcttt
     4081 tctatcccaa gtttctaaat taataatatt aaaagtcata tataattttc ctcctaaatt
     4141 tcatcttatt tctttatatt taggaggaat aatcctctga ttttttcata tattatgtca
     4201 cctcttaaat attaattata gggttctgtt gcaaagtttt aaataaagaa taaaatccct
     4261 tacggtatct atgatttaag ctgggattcc caataatacc ttgatttcag tacagaccga
     4321 aaacccgaag agagtgcctt cttttcgggt tttcttatat aatcctcgaa tggcttccat
     4381 gcctttaatc gtggtagagg cagtgcgtaa acttcgatag aatttattgc gtctctttac
     4441 tggacgatgg tcttgttcaa tcaaattatt caggtattta atggtacgat gttctgtccc
     4501 ttgataaaag ccgtattctt ttagtttctt aaaggcactt gtaatagagg gggctttatc
     4561 tgtgactaca accttcggtt catcaaactg cttcactaac cgcttaagaa aagcataggc
     4621 tgcttgtgtg tcccgttttt tacgtaacca aatatccaag gttaaaccat ctgcatcgat
     4681 ggctcgatac aaataatgcc attttccttt aattttgatg tacgtttcat ccattttcca
     4741 tgaataaaag gattttttat ttttcttttt ccaaatttga tagagtagtt tgccatattc
     4801 ttgcacccaa cgataaatcg tcgtatgaga aacgttaatg ccacgatcat ataagatttc
     4861 ttgaacttca cgatagctaa ggttataacg aagatagtag cccacggcta caataatcac
     4921 atcctgctga aattgctttc ctttaaaatg attcatcgtc attcctcctg ctatcttttt
     4981 ctattattct accttatttg atagtagatt taaaactttg caacagaacc cctgaatgta
     5041 agtttacttt agctgaacat tttagaaaga aaaaactaac caaaacgaat gtaaaagaat
     5101 tactggaggg aaaagaaacc ctggtaaaag gaatcaaaaa caaagagaaa aagccctaca
     5161 atgccgttgt aaaaattggg gaaaagggat atattgattt tatatctttc tcaaaataaa
     5221 cataaaagcc ctttaaagag ggcttttata tattaatcac aaatcactta tcacaaatca
     5281 cttatcacaa atcacaagtg atttgtgatt gttgatgata aaataagaat aagaagaaat
     5341 agaaagaagt gagtgattgt gggaaattta ggcgcacaaa aagaaaaacg aaatgataca
     5401 ccaatcagtg caaaaaaaga tataatggga gataagacgg ttcgtgttcg tgctgacttg
     5461 caccatatca taaaaatcga aacagcaaag aatggcggaa acgtaaaaga agttatggaa
     5521 ataagactta gaagcaaact taagagtgtg ttgatagtgc agtatcttaa aattttgtgt
     5581 ataataggaa ttgaagttaa attagatgct aaaaatttgt aattaagaag gagggattcg
     5641 tcatgttggt attccaaatg cgtaatgtag ataaaacatc tactgttttg aaacagacta
     5701 aaaacagtga ttacgcagat aaataaatac gttagattaa ttcctaccag tgactaatct
     5761 tatgactttt taaacagata actaaaatta caaacaaatc gtttaacttc tgtatttatt
     5821 tacagatgta atcacttcag gagtgattac atgaacaaaa atataaaata ttctcaaaac
     5881 tttttaacga gtgaaaaagt actcaaccaa ataataaaac aattgaattt aaaagaaacc
     5941 gataccgttt acgaaattgg aacaggtaaa gggcatttaa cgacgaaact ggctaaaata
     6001 agtaaacagg taacgtctat tgaattagac agtcatctat tcaacttatc gtcagaaaaa
     6061 ttaaaactga acattcgtgt cactttaatt caccaagata ttctacagtt tcaattccct
     6121 aacaaacaga ggtataaaat tgttgggagt attccttacc atttaagcac acaaattatt
     6181 aaaaaagtgg tttttgaaag ccatgcgtct gacatctatc tgattgttga agaaggattc
     6241 tacaagcgta ccttggatat tcaccgaaca ctagggttgc tcttgcacac tcaagtctcg
     6301 attcagcaat tgcttaagct gccagcggaa tgctttcatc ctaaaccaaa agtaaacagt
     6361 gtcttaataa aacttacccg ccataccaca gatgttccag ataaatattg gaagctatat
     6421 acgtactttg tttcaaaatg ggtcaatcga gaatatcgtc aactgtttac taaaaatcag
     6481 tttcatcaag caatgaaaca cgccaaagta aacaatttaa gtaccgttac ttatgagcaa
     6541 gtattgtcta tttttaatag ttatctatta tttaacggga ggaaataatt ctatgagtcg
     6601 cttttttaaa tttggaaagt tacacgttac taaagggaat ggagataaat tattagatat
     6661 actactgaca gcttccaaga agctaaagag gtccctagcg cctacgggga atttgtatcg
     6721 ataaggggta caaattccca ctaagcgctc gggacccctt gtaggaaaat gtcctaagtg
     6781 tggcaacaat attgtattaa aaaaatcgtt ttatggttgt tcaaattatc ctgaatgtaa
     6841 gtttacttta gctgaacatt ttagaaagaa aaaactaacc aaaacgaatg taaaagaatt
     6901 actggaggga aaagaaaccc tggtaaaagg aatcaaaaac aaagagaaaa agccctacaa
     6961 tgccgttgta aaaattgggg aaaagggata tattgatttt atctcttttt caaaataaac
     7021 atggggctga cccaaaagta gctcctatat gaaaaataga ggtctttcca tttagatagt
     7081 agtggaaaga ccggctcttt gtcaataagg actgatgagt tgtgcaaaat caaatctgag
     7141 tcagaatgaa ccacattctg gctcagattt tttgttatct tacattgatt aattgattga
     7201 tcaaaaagat tctaattctc atgttctcaa atgatttaaa tccgtaggat actcgtttca
     7261 ttgtctttat gtgggtattc ttcgcttcta tttttccatt ggaataagga tagatcattg
     7321 cgttggtgat gccttcttca taggtcagaa ggttttgaag cttttcccga aagctgtcat
     7381 ctaacgtttc gggaagttct gccaataagg agaaaaataa gtcagggtct ttgtctcgaa
     7441 aggcttcaac taattcatga aaaaagggat acgcctcctt taggggcgga gaaaactcaa
     7501 gcaatcgatc aatcatcatt gcttcagtaa gaaatgggta ttttggtgct cggaaacttt
     7561 tccatgtttt gtattcataa tggttgatgt ttgcacgatt ttttagcaaa aagcgccagt
     7621 tctttttcag tttttctgcc tggcttttct gtccggcttt acgaagttca ttcatttcac
     7681 ggatacgcaa ctcattgaac gcttgattca tgtgtttgac aatatgaaac cgatcaatca
     7741 cgactttcgc atttggcaga acacgtttgg tgagctggaa gtaggcggcg ttcatgtctg
     7801 tcaccaagaa ttctacttct tctggattgg tacaacctaa gaaatagctt gttaatcgag
     7861 gtaatttacg cgtaggcaaa acatctatta attttcctgt ttcgccatcc gcgcaaataa
     7921 agctcatctt atcttctatg gaagcatgcg aacgaaattc gtcaaccatc aatactctgg
     7981 ggaggatctt cttagattgc tttggtaaat agcttttaaa ctctttcaat gtacgaataa
     8041 cggtggtcaa agatacctga cagcttttcg caataaaaga taaagatact ttttcagtca
     8101 gtaaagaagc aattttatat ctaacatgat ttgcgattga atgtctgggt tggacaaaat
     8161 aactttgagc cgtccaatgg gtgcgacagt ttttacaggt atagcgttgc ttttttaggc
     8221 gcataaccaa aggcatatga ttgtattgtt caaaacggac aatcgtttcc ttttttccat
     8281 ttttcactat aattgctttc ccgtttccat ctaccacagt agaaccacaa cttctacaag
     8341 cacgaggagt aggcgagaga acagcatcga cgaccaacgt ctttttcttc tgaagggtct
     8401 cgtaagagac ctctgtaatc atcaaatctt tctctgttat tctcagcatt tttttgatag
     8461 aatcattcat atagcgtatc gtcctctcag ttgtttattt tgtggtgatt taatcatact
     8521 agagaacgat atgtttttta atacctaaaa tgaaaatggg gctgaagaat caattctgat
     8581 tcatcagtcc cataaattat agagccgaaa gacctctatt tatcttttga aagtgaatac
     8641 aaaaataaag cacactctgc tataatatag gtgattaatc catttgagag aggtgcttta
     8701 tcatgtatca aaattatacc ataaaccaac tttgtttgcc tatagatctt gaaattaaat
     8761 tagaagaaaa tgattttgct catgccattg tgcagtttgt tgactctatt cccgatgaag
     8821 tctttcttcc ttattatcaa tctatgggta gaccccaata tcatcctcgt atgctacttt
     8881 ccattattct ttgtgcctat attcaagggg tttattcggg ccgccaaata caaaatatgc
     8941 tgatagatag tattcggatg cgctacttat ctcaagagca attccctaac tttcgtacta
     9001 ttaatcgttt tcgcgttcat ccgattatga acgatattct agatcattca tttgttcaat
     9061 ttcgtgagct actggttcaa agtggcttaa tcagtggcag tgctctatac attgatggta
     9121 caaaaattga agcggatgcg aataaatact ctttcgtttg gaaaaaaagt attttaaagt
     9181 ataaggatag ccttgatcaa aaagcccttg aaaactacca acaaatggtg gaaacaaaaa
     9241 tcttacctga gttaatagat gatttaaagg atgaactttc tatagaagag attgaaagga
     9301 ttcgtcaatc tttggaagaa aaggaaaatc aattaattga agcgattgac caaaccgaaa
     9361 cagtagaagg gggctgaccc attattaata aggagtggac aacatgattg atgtaaatga
     9421 gctattggaa gaagctatta gagaaactga aaatctaaat gatggcgaag tttttcttgt
     9481 taaagattta ttcaagggat atgtggggaa taggataccc agaaaggatc gacttctgct
     9541 tggaacgtta tttttaaacc atgttagcaa aatgaatggt aatttaaagg ctattgaaaa
     9601 gacttcatct aatcagcaga ggtataaaaa gacaattgat aagttttaac tatcttttgt
     9661 gaaattaaaa aaattataaa tatgttgagt agaagcaaaa gatttggctt ggaattttta
     9721 cagcagtgaa tcgataaaag gagcatgctt gatggtagat aatattatta aatcagtagc
     9781 agagaaatta tcctctctgt cttatataga aggtattgtt ttaggtggtt cacgtgcaag
     9841 gggcacccat acagaggatt cggatataga tatcggcatc tattacaatt cagaatcatt
     9901 tgacataaat actattaatc aattcgctac aaagctggat gatgagcata gaaataacct
     9961 tgttgtacct cccggagcat ggggtgattg gattaatggc ggcggatggt tagtcataaa
    10021 cgggtatcat gtggatttaa ttttacgtga tattaaacgt gtggaacaaa taatgaaaga
    10081 tacagagcac ggaattgtta ctgccaatta tcagactggg catccccatg gttatattag
    10141 tgcaatgtat cgaggagaat tagcgattag caaaatacta tatgctaaga atgaaagctt
    10201 atgcgaatta aaaaaacagg cagaaactta tcccaatgct ttgcagaaaa gtttagttaa
    10261 cttttttatg tttgaagcag ggttctcttt aatgtttgta aaagcaaatt cgggaacaga
    10321 cgataaatat tatattgcgg gtcatgtttt tcgtatagtt tcatgtttaa atcaagtgtt
    10381 atttgcatgt aataatgctt attgtatcaa cgaaaagaaa gctataaaac tgcttgaaac
    10441 ttttgaacat aaacctgaaa aatataccga gaaggtaaat catatttttg aagtactcgg
    10501 tatctcactt tttgaatgct acgacatgac cgagaagctt tataatgaag tgaatgaaat
    10561 tgtatcggag ataaataact ttttaaacga ggagagttca gatgaaagaa aacaaatatg
    10621 atgataatat attttttcaa aaatacagtc aaatgagtcg ctcgcagaaa ggactggctg
    10681 gtgcgggaga atgggagact ttgaaaaaga tgctacctga ttttaagggt aagcgtgtgc
    10741 ttgatttagg atgcggctat ggatggcact gtatatatgc gatggaaaac ggtgcttcct
    10801 ctgtagtagg tgttgatatt tctcataaaa tgctcgaagt agcaaaagga aaaacccatt
    10861 ttccacagat tgaatatgaa tgctgtgcca tagaagatgt ggatttccca gaggagagct
    10921 ttgatgtaat actaagttcg cttgcgtttc attatgtagc agactatgag aatttaataa
    10981 aaaagatata taggatgctg aaggctggtg gcaatttagt ttttacagtt gaacatcctg
    11041 tttttactgc tcatggaaca caagactggt attataacga aaaaggagaa atactgcatt
    11101 tcccggtgga caattattat tatgagggca aacggacagc tatgtttttg gaagaaaagg
    11161 ttacaaaata tcatagaaca ctgaccacat atctaaatac actgctttca aatagtttta
    11221 taataaatca gattgtggag ccacagccgc cagagaacat gatggatatt ccggggatgg
    11281 cggatgaaat gcgacgccca atgatgctga ttgtatcggc aaaaaagaag atgtaataat
    11341 atagaaaaaa taaacgagga gtatgtaaat gagatcagaa aaagaaatga tggatttagt
    11401 actttcttta gcagaacagg atgaacgtat tcgaattgtg acccttgagg ggtcacgcgc
    11461 aaatattaat atacctaaag atgaatttca ggattatgat attacatatt ttgtaagtga
    11521 tatagaaccg tttatatcta atgatgactg gcttaatcaa tttgggaata taataatgat
    11581 gcaaaagccg gaggatatgg aattattccc acctgaagaa aagggatttt cctatcttat
    11641 gctatttgat gattacaata aaattgatct taccttattg cccttggaag agttagataa
    11701 ttacctaaag ggcgataaat taataaaggt tctaattgat aaagattgta gaattaaaag
    11761 ggacatagtt ccgactgata tagattatca tgtaagaaag ccaagcgcaa gggagtatga
    11821 tgattgctgc aatgaatttt ggaatgtaac accttatgtt attaaaggat tgtgccgtaa
    11881 ggaaatttta tttgctattg atcattttaa tcagattgtt cgccatgagc tgctgagaat
    11941 gatatcatgg aaggtcggca tcgaaacagg ctttaaatta agtgtaggca agaactataa
    12001 gtttattgaa aggtatatat ccgaggattt gtgggagaaa cttttgtcca cctaccggat
    12061 ggattcctat gaaaacatat gggaagcatt atttctatgc catcaattgt tcagggcggt
    12121 atccggtgag gtggcggaaa ggcttcatta tgcctatccg gagtatgata ggaatataac
    12181 aaaatatacc agggacatgt ataaaaaata cactggtaaa accggctgcc tggatagcac
    12241 atatgccgct gatatagaag agaggcggga acagtgatta cagaaatgaa agcagggcac
    12301 ctgaaagata tcgataaacc cagcgaacca tttgaggtga taggtaagat tataccgagg
    12361 tatgaaaacg agaattggac ctttacagaa ttactctatg aagcgccata tttaaaaagc
    12421 taccaagacg aagaggatga agaggatgag gaggcagatt gccttgaata tattgacaat
    12481 actgataaga taatatatct ttactaccaa gacgataaat gcgtcggaaa agttaaactg
    12541 cgaaaaaatt ggaaccggta cgcttatata gaagatatcg ccgtatgtaa ggatttcagg
    12601 gggcaaggca taggcagcgc gcttatcaat atatctatag aatgggcaaa gcataaaaac
    12661 ttgcatggac taatgcttga aacccaggac aataacctta tagcttgtaa attctatcat
    12721 aattgtggtt tcaaaatcgg ctccgtcgat actatgttat acgccaactt tgaaaacaac
    12781 tttgaaaaag ctgttttctg gtatttaagg ttttagaatg caaggaacag tgaattggag
    12841 ttcgtcttgt tataattagc ttcttggggt atctttaaat actgtagaaa agaggaagga
    12901 aataataaat ggctaaaatg agaatatcac cggaattgaa aaaactgatc gaaaaatacc
    12961 gctgcgtaaa agatacggaa ggaatgtctc ctgctaaggt atataagctg gtgggagaaa
    13021 atgaaaacct atatttaaaa atgacggaca gccggtataa agggaccacc tatgatgtgg
    13081 aacgggaaaa ggacatgatg ctatggctgg aaggaaagct gcctgttcca aaggtcctgc
    13141 actttgaacg gcatgatggc tggagcaatc tgctcatgag tgaggccgat ggcgtccttt
    13201 gctcggaaga gtatgaagat gaacaaagcc ctgaaaagat tatcgagctg tatgcggagt
    13261 gcatcaggct ctttcactcc atcgacatat cggattgtcc ctatacgaat agcttagaca
    13321 gccgcttagc cgaattggat tacttactga ataacgatct ggccgatgtg gattgcgaaa
    13381 actgggaaga agacactcca tttaaagatc cgcgcgagct gtatgatttt ttaaagacgg
    13441 aaaagcccga agaggaactt gtcttttccc acggcgacct gggagacagc aacatctttg
    13501 tgaaagatgg caaagtaagt ggctttattg atcttgggag aagcggcagg gcggacaagt
    13561 ggtatgacat tgccttctgc gtccggtcga tcagggagga tatcggggaa gaacagtatg
    13621 tcgagctatt ttttgactta ctggggatca agcctgattg ggagaaaata aaatattata
    13681 ttttactgga tgaattgttt tagtacctag atttagatgt ctaaaaagct ttaactacaa
    13741 gctttttaga catctaatct tttctgaagt acatccgcaa ctgtccatac tctgatgttt
    13801 tatatctttt ctaaaagttc gctagataga gttctatatt agagatgtaa agagttttgg
    13861 tgaagaggtt tgtgagtatg gcttttataa ccagggtgca atgagaagca ctaacagcag
    13921 ctagcttaag aacgcatagg atatactttt tatggaagtc acagaggagg aataaaattt
    13981 gaacaggatt aacagagtaa cctctattct tattcagctg caatcaaaaa aaaggttctg
    14041 ttgcaaagtt ttaaataaag aataaaatcc cttacggtat ctatgattta agctgggatt
    14101 cccaataata ccttgatttc agtacagacc gaaaacccga agagagtgcc ttcttttcgg
    14161 gttttcttat ataatcctcg aatggcttcc atgcctttaa tcgtggtaga ggcagtgcgt
    14221 aaacttcgat agaatttatt gcgtctcttt actggacgat ggtcttgttc aatcaaatta
    14281 ttcaggtatt taatggtacg atgttctgtc ccttgataaa agccgtattc ttttagtttc
    14341 ttaaaggcac ttgtaataga gggggcttta tctgtgacta caaccttcgg ttcatcaaac
    14401 tgcttcacta accgcttaag aaaagcatag gctgcttgtg tgtcccgttt tttacgtaac
    14461 caaatatcca aggttaaacc atctgcatcg atggctcgat acaaataatg ccattttcct
    14521 ttaattttga tgtacgtttc atccattttc catgaataaa aggatttttt atttttcttt
    14581 ttccaaattt gatagagtag tttgccatat tcttgcaccc aacgataaat cgtcgtatga
    14641 gaaacgttaa tgccacgatc atataagatt tcttgaactt cacgatagct aaggttataa
    14701 cgaagatagt agcccacggc tacaataatc acatcctgct gaaattgctt tcctttaaaa
    14761 tgattcatcg tcattcctcc tgctatcttt ttctattatt ctaccttatt tgatagtaga
    14821 tttaaaactt tgcaacagaa cccaacggaa gatgtgtcac actttttaac aaacaaagaa
    14881 catttgaatg aagtaatcag acggattcaa aaagacttta gttgtatgga agaaatgaag
    14941 tactttattc aaagagtcga agaacaattg tatttggaaa gtgaaacgag tcaaacgaag
    15001 gtcacagtca gccataatcg tttagacgtg tataaacgtc gtcctgaaac ggtaaaaaaa
    15061 ggaacggagc ttctacgact agaaacagaa aaatacatca tgaatgttta cctagaaagg
    15121 agtgagctgg tcgaaaactt tgtcagctac acgatttgca ggaaacacta ttactcagaa
    15181 tcagaatatt attcaatttt tgagagcatg gaattaatgg aagaagaaat ggaagagcta
    15241 aacagcaaag atgcgacgat agacgattat taccttgtat ttactagatt tttgacgtgt
    15301 ggaacggaat ctatcgtgtt aatgggaatg gattatgaac tcgctgtacc cgaagcattt
    15361 ttgagggaat atgtagaaga agtagataac ccaggcgacg actggtacac gactttaact
    15421 gattttttag acacctatac ttacgacgat acagaagaaa tccaaaatga acttgaccgt
    15481 aaacgaatgc catatcaacg atttgaaagg aaaaaaaggc aataatcatt tataccgaaa
    15541 agtgagaatg tgtgaaataa ggacaaaaaa cctagtaact aagggaatgg ttcttatttc
    15601 gcaccaatcg ctccaaccgc ccccgccgct taggtggtgc gaaataagcg ggcaacaccc
    15661 gataacctaa gagaaagaag gagatccata tgaataaaat cattcctcta ttgttagtcc
    15721 tatttgttgg cgaaatactt atgcgccatg ctgcagctgt gcatttaaac ttcgtagtat
    15781 ttttggcaat actggtattt tgtttgatct tttggcgctt tgtattagcc cttgtgagtc
    15841 tactattcaa gatgattgca gccatatttt tcatagggtt atttcgatga aaggagagag
    15901 tactaatgcc aattgcaata ggaaataaac ggttacccgt tacgttggat gaaaagagac
    15961 aaaaagaatt gcagcaacta aagcagaagt acggcaaaag tgaatccagg attatgtgta
    16021 ttgcgttaga tttattgatt gcccaagaaa aagcaggatt tgaggtacca gcactcaaaa
    16081 agtgacgtca ctttttatcc taaaaactaa aagtgatagc acttttaatt ataagaagtt
    16141 agaatattaa tcatttgctt aattgtacaa tataatgtac aattgtttta tagaaataaa
    16201 taaggggtga aaggaatgga agcagtagct tattcaaatt tccgccaaaa tttacgtagt
    16261 tatatgaaac aagttaatga ggatgctgaa acacttattg taacaagtaa agatgtagaa
    16321 gatacagttg ttgtattatc aaaaagagat tatgattcta tgcaagaaac gttgagaaca
    16381 ctttctaata attacgtcat ggaaaaaatt cgtcgaggag atgaacaatt ctccaaaggt
    16441 gcatttaaaa cacatgactt aatcgaggtt gaatctgatg attaaggctt ggtctgatga
    16501 tgcttgggat gattatcttt attggcatga gcaaggaaac aaaagcaata taaaaaagat
    16561 taacaagtta ataaaagata tcgatcgttc cccctttgct ggattaggaa aacctgagcc
    16621 attaaagcat gatttatctg gaaaatggtc cagaagaatt acagatgaac atagactgat
    16681 atatagagtt gaaaatgaaa cgatatttat ttattctgca aaagatcact attaaccaat
    16741 cggaagtaag gaaagggtca gaaacttaaa agtttttgat ccttatttta tttaccctag
    16801 tcatttaaaa agctaatata gcttagtgtt gattgttatt aatgaatgtg tttgttacgc
    16861 gtattacgga tataaggtta gtaaaatcat ttctaaagtt gaggaaaagt aaatataaat
    16921 ggcttaaatt tcaacaattt gaagttgaat agatatgtta taatactatt gtagtgtggg
    16981 atgttagtta ctaaaggatg acgcttatat atatgactga atagaataag caataggttt
    17041 aataatctat tttaaatttt ttgtactagt tttagttaat tagcaaaaac aacaaaaata
    17101 aacttctcat agaatttagc taaaaattaa tgatttattt acatattaaa tttggataca
    17161 gttaagtaat ttttatatat tggaggagaa gtaatggaat ataaatttaa cttgaatttg
    17221 aaagaagtac tccccactca gggaacaata aacataaatg gtcaagataa tgatgacgat
    17281 atagtaataa aaaaaataga atttattgat tctgatataa atgttttttt ttattctaaa
    17341 gaaaaattag ctgattttag caatattgct gaaatgattg aacgtttaaa agattttatg
    17401 atcagtgttt gggatgtagc gatgcttgct gacgaatcaa attatacttc gagcatatac
    17461 agattagaag atagtaattg gatagaaatt tcattagagt taaagacact tcctaattcc
    17521 gttaactata taattagaga tataacttct gaagctcaac aattagttaa ttacatgcat
    17581 ggacacgaaa gtatcccctt ttctcttata ctccttaaaa gaagtaaaaa tatatcaaat
    17641 actagagata ggtttatttc gataattaca gcctgtgaaa taggggtaaa ggaattttat
    17701 caacaagaga aacctgattt aactctaata tttgagaatt tacaatctcc ccctgtagac
    17761 aaattattag ggagcatgtt taaagggtac tttaatattg agtttccgaa agaaataaga
    17821 aaggaaatta aaaatttcat agaaaaacgt aataaattgg ttcattctcc tcaaggaagt
    17881 aaaccaacta tagaagaatg ttttgaatgt tatatggcag tgctaaaaac atttaatttt
    17941 ttttataaaa ttaatgatag ctttatgtat agagattttt atgaagaatc tatagaattg
    18001 actccaacgg aaccaaataa atctcaaatc actttgtcaa aggagctaga gagaaaagta
    18061 gagtctcaag aactagctat aggaattagt ataaccaatg tgtcgacata caaagaatta
    18121 tacgaagcta aatcacaaga taataaggat tttgtagaaa atatagataa ggaaccaaca
    18181 aatacagtag gggattaacg taaataagtg aagattatat taacagactc tttatttagt
    18241 taagtaaaaa atggtttgtt ggaattttat gctttatctg ttctgagtaa gacttaattt
    18301 tatagatagt aattatatgt aggaaattaa agatgagaag ataataaaag cagcatgatc
    18361 aactatttgt cattgaccat gctgtctttt tttattctat acacggtttg tctcgtaaca
    18421 ttgtagtctt tagcaatctt agcaatcgca acaccatttt taagatcttc aacgatgctt
    18481 ttgtaaacaa ggcgacgttg gggatctttt gcgtctgcac tgtataattt gggccgccct
    18541 ttgtagacgc cgtttgcttt tgcgatctta attccttgtg cctggcgacg tttcgattca
    18601 gtccgttctt gttcagcgat catggccaaa atttggatga tcagatcctt aatgaattta
    18661 tccaggagag gattgccaat tgcttcagcc atgatcggta aactagtaat gatcagcttc
    18721 acatttttct tcttcaagta attgactgaa gcgatgatct cgtcataatt tcttccaagt
    18781 cgatcaatag cttccacaat aaaaatatct tgatctcgga cgtaatctaa tgcttcttgg
    18841 aaaacaggtc gatgagtaat cgttgcgcca gattgtttct cgatgaaaat tctctctgca
    18901 ccgaattttt tcatttcttc aatctggcgt tgttcatttt gatcgatcga tgagacacgt
    18961 atgtatgcaa ctctcaaaac ttttacctac tttctgcaac tatttaaaat acaccctaat
    19021 catacacgag gaagccatat ttttcaatgt tataccagtg tctatttagg gtaaacctta
    19081 tatagacaaa aactaatgat ggaggaaata gtatgagaat tttttgtaag tgtctactga
    19141 taacttattc tcaaatgttg taaggatttt attcatttgt taatattaaa gaacggaact
    19201 ccaaaaaagt ccgtactcta atttgcagtc tctcactctt ttagagtgag agtttttatt
    19261 agattttcaa attaattagt aaagtgatag aataaattga tcatacaaat caaaagaaga
    19321 agcagggtga tagcatacct atgcttcttt ttttatgtat ttagctattt cttctttaca
    19381 atatcgaaca tatgtttgta taatgtgaaa gaatggagtg ttatttatga tggattattc
    19441 aaaagagcca gtaaatgatt actttttaat cgatatgaaa agcttttacg caagtgtcga
    19501 atgtatagaa agaaatttag atccattaac aacagaactt gttgttatga gtcgagctga
    19561 taatactggt tcaggattga tattagcttc ttctcctgaa gcaaaaaagc ggtatggtat
    19621 tacaaatgtg agtagaccac gtgacttacc acaaccattt cctaaaacac tacacgttgt
    19681 tccaccacgt atgaacctat atatcaagcg aaatatgcag gtaaataata ttttcagaag
    19741 atatgtggct gatgaagatc tactgattta ctcgatcgat gaatcaatct taaaagtgac
    19801 ccgatcactg aatcttttta cgactgaagg aacacgaagt caacggagaa agaagctggc
    19861 tcaaatgatc caggagaata ttaaagaaga gctaggattg attgctacag taggtgtcgg
    19921 agataatccc cttttggcta aactagcctt agacaacgaa gcaaagcata atgaaggatt
    19981 tgttgcggaa tggacgtacg aaaacgttcc tgaaaaagta tggaatattc ctgaaatgac
    20041 ggacttttgg ggaattggct ctcgaatgaa aaaaagactc aatcagatgg ggattatgag
    20101 cattagagat cttgctaact ggaatcctta tacgattaag aatagactag gtgtgattgg
    20161 cttacagctg tacttccatg ctaatgggat cgatcgaaca gatatagcaa tcccaccaga
    20221 accgacaaag gaaaaatcat atggaaattc acaagtgtta ccacgagatt atactagaag
    20281 aaatgaaatc gagctggtgg taaaagaaat ggcggaacaa gtagcgatac gcattaggca
    20341 gcataactgt aaaacaggtt gtgtccattt acacattggc acgtcgatct tagaaacgag
    20401 accagggttt tcacaccaga tgaagatccc tatcacagat aatacaaagg aattgcagaa
    20461 ttattgtctt ttcttgtttg ataagtatta tgaaggacaa gaagtaaggc atgttggaat
    20521 aacctatagc aagcttgtgt acaccgattc gcttcagctg gatttattta gtgatccaca
    20581 aaagcaaatt gacgaagaaa atttagataa aattattgac aagattcggc aaaaatatgg
    20641 ttttacgtcg attgtacatg cttcttcaat gttagaaggc gctagaagca ttactagaag
    20701 cacacttgtt ggtggtcatg cgggcggaaa tgggggaatt aaaaatgatt gattacaatg
    20761 atcgtggacg tttaaagtgg gcagggtttt atttatctga tcatactgaa gaaattgatg
    20821 ccgacaatga acaacgaacc agtcaaaatt tagcaaaaga acaaatgacg actgaagaga
    20881 ttgcggaagt attgaacgct gcagtcataa aaaatagatc agtatctatt caaaaagaag
    20941 aacgaaacgc tgaaggatac tatccagaag atatcattgg caagatctta ggtagtgatg
    21001 agctggggat ctacgttgga aaagacaaaa ttcactacga cgaaatacgt catatcgaat
    21061 tttaccagga taataaatgg agtcgattag aatgaacatt atccagcaat atgagctaaa
    21121 gtatataacc tttgatcagc tatcagaaga gatttggggt tatggccaac gtttgataaa
    21181 tgaggttggt gttgagcgct tctctttcta tgtagaagct gcagcaggtt atcataattt
    21241 taggttttat atcttcccgt tatatatata aggtatttta cggattctat agagttatct
    21301 ctatgaatcc ttttttgttt ttacaaatag gagtagatac tagaataatg cgtgtgttaa
    21361 actattattg caaacgcaat aataaaagaa agtaggctta cgcaccatgt ctatcaatac
    21421 atttgtttac tcgcacccga tcaatgttta cattatcaag aatttaggaa tcactgtaga
    21481 acaattttgt gagttatatg cctacccaca aggaacggtt gcaagctgga taacccgaca
    21541 acgtagaata aaatcattac ctgcttcatt cgtttatgat ttaagcctgg cctctagttt
    21601 aaacatgtct gatgtttatg aaaagctcct gtctttagaa aaagaatatg attccttcaa
    21661 gattaaacat gataaaaaaa taaaaaaaca tatataatat caatcacaat tgtataatat
    21721 tacgatatct taatatcatg atatcgtaat attgtttttt tctaagaaaa tgcactataa
    21781 gaagggaatt attagtaaca atatagacag tttagtaatg tttaaattat tctagttgct
    21841 gctcgcaaaa catatttctt atcattaata aaaaatttta aagtaataaa aagtgattat
    21901 tttaatttcg aataacatat gaataatctt tatatccgaa ccgatatata tctttaaaac
    21961 aaaataatca cacaatatta caatataatg catatacgat attgcaatat cacaatatta
    22021 tgatataatt atattataat ataagatgaa tgggggatat tttaatggca agaatattgt
    22081 cagtagccaa tcaaaaaggt ggagtttcta aaactacgac tagcgttaat ttagcagcat
    22141 gtttgaaatt tgtttacggt aaaaatgtac ttttagtgga cattgatcct cagggaaatg
    22201 ctacagataa tgtaggtttc gatatagatg gaacaaacca acctacaatt tatgaagtat
    22261 taaaagggga ggctgacatt acagatgcta ttctggacta taaaggaatt gatgttttgc
    22321 cagccgacat agccctttct tctgcagaga gggaatttac tcaagtagga agtgaacaca
    22381 ggcttaaaag agtacttcaa ccaatcaagg acaactatga ttatattata attgattgtc
    22441 caccaagttt aggaatgctt acagtcaacg catttactgt ttctgatgaa attatcattc
    22501 cagttgaagc tgcgtatttc tcattaaaag gactaataaa gttaagtgaa actattgaaa
    22561 cggtaaaaga atatacgaac gacaagcttg aagtacgagg agttctattt actaagtata
    22621 ataagcgtta taacatttct aaagaaatga cgtctgcagc aaccgaaatt tctagagtca
    22681 ttggtgcaaa aattttcaaa acttatattc gtaggacaat aaccgttgac gaagcgcaag
    22741 ctgctggatc agatctaatc aattttaata aaccctcaac agctgaagat gactataaag
    22801 catttacaga agaatattta aaagaagttg gtgattttga tggcagaaga taatcgcagt
    22861 caagctgcag taagtagatt actaggaaat aaaaataaaa agaattttaa atcaaaagaa
    22921 gtagaagaaa tcgaattaac caagaaaaat ataagtaaag tcataaaaga tcaaggaagt
    22981 agtgtaagaa cagcagatag cattcgtata aatccaattc taatgtcagc actcaaatat
    23041 tggacgacta ttgctgaatc agacaaaagt aaaccagacg ttatagaaga tgcgctatta
    23101 aagtccatac ctgaagaata cttgattgaa ggatataaac tagcaaagaa acaaaataaa
    23161 atttaattta cattcaatat cacgatatca taatatcgtg atattttttt tataaaaatc
    23221 agtagtatca aagctgataa gtcgcttatc ttcatattgt aatattacga tatcgtgata
    23281 taatattatt gtaatatcgt gatatagtta ctatgagctt aaaccttgaa atagagcggt
    23341 ttgctttaat ttatttttta aggtaaacta aaaaaagata aaaaaagact actgctttaa
    23401 caaagtttgg cgacttatca gcagtagaaa aatatatagt ggatagatat atttgtttaa
    23461 ttcattgtaa catagttttg aacaaaacgc tatcctacag aaagaggatt ggct
//
