LOCUS       NZ_CP096694            22354 bp    DNA     circular CON 21-MAY-2024
DEFINITION  Acinetobacter baumannii strain 5773 plasmid p5773_1, complete
            sequence.
ACCESSION   NZ_CP096694
VERSION     NZ_CP096694.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN24114679
            Assembly: GCF_023361095.1
KEYWORDS    RefSeq.
SOURCE      Acinetobacter baumannii
  ORGANISM  Acinetobacter baumannii
            Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales;
            Moraxellaceae; Acinetobacter; Acinetobacter calcoaceticus/baumannii
            complex.
REFERENCE   1  (bases 1 to 22354)
  AUTHORS   Gao,Y., Li,H. and Wang,H.
  TITLE     Origin, phylogeny, and transmission of the epidemic clone ST208 of
            carbapenem-resistant Acinetobacter baumannii on a global scale
  JOURNAL   Microbiol Spectr (2022) In press
REFERENCE   2  (bases 1 to 22354)
  AUTHORS   Gao,Y., Li,H. and Wang,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-DEC-2021) Department of Clinical Laboratory, Peking
            University People's Hospital, No.11 Xizhimen South Street, Beijing
            100044, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 208x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023361095.1-RS_2024_05_21
            Annotation Date                   :: 05/21/2024 04:14:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,938
            CDSs (total)                      :: 3,842
            Genes (coding)                    :: 3,732
            CDSs (with protein)               :: 3,732
            Genes (RNA)                       :: 96
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 59 of 110
            Pseudo Genes (incomplete)         :: 43 of 110
            Pseudo Genes (internal stop)      :: 14 of 110
            Pseudo Genes (multiple problems)  :: 6 of 110
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP096694.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..22354
                     /organism="Acinetobacter baumannii"
                     /mol_type="genomic DNA"
                     /strain="5773"
                     /isolation_source="secretion"
                     /host="Homo sapiens"
                     /db_xref="taxon:470"
                     /plasmid="p5773_1"
                     /geo_loc_name="China:Xinjiang"
                     /collection_date="2012-03-03"
                     /collected_by="Yue Gao"
     gene            299..1234
                     /gene="repM"
                     /locus_tag="M1S18_RS19125"
                     /old_locus_tag="M1S18_19125"
     CDS             299..1234
                     /gene="repM"
                     /locus_tag="M1S18_RS19125"
                     /old_locus_tag="M1S18_19125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005065049.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepM"
                     /protein_id="WP_001292329.1"
                     /translation="MSELIVKDNALIQASYTLDTVEQRLILLAIAEARETGHGITENSL
                     LEVHASSYINTFNVEKHTAYTVLREASKSLFDRYVTYHDINPKTGKDRSFHCRWVDKIG
                     YESQSGIIFLRFTQDIVPLITRLEENFTKYELQQVSRLSSSYAIRLYELLIQWRSAGKT
                     PLFDLSIFRQQLGVKPHQYKTMSNFKTYVLDFALKQVNELTDITAKYEQHKKGRSISGF
                     SFTFKQKKMSNLPIKNKRDPDTIDIFSKMTDAQRHLFSHKLSELPEMGKYSHGTESYPQ
                     FAVRIAEMLQNPEKFKELYPYLQKVGFKAA"
                     /name="repM"
     gene            1312..1830
                     /locus_tag="M1S18_RS19130"
                     /old_locus_tag="M1S18_19130"
     CDS             1312..1830
                     /locus_tag="M1S18_RS19130"
                     /old_locus_tag="M1S18_19130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication DNA-binding protein"
                     /protein_id="WP_000839337.1"
                     /translation="MKSLTVLELSKLYNINRQTIYNNIKKGILSKNSDNKIDLAEAIRV
                     FGEPVQKQSVKETVKVDSPTSAEVLLLRQQIDLLKNQLDDAKNRESFYQNQIETMQRLL
                     EAPKTNTTQSDDPGSTQAESTVEEKEDVIAMPPKESEVIENKRIPVPEHIEPEPEKRGF
                     WSRFFKPYG"
                     /name="plasmid replication DNA-binding protein"
     gene            2040..2339
                     /locus_tag="M1S18_RS19135"
                     /old_locus_tag="M1S18_19135"
     CDS             2040..2339
                     /locus_tag="M1S18_RS19135"
                     /old_locus_tag="M1S18_19135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000358348.1"
                     /translation="MDKKIEEKTKDINEKIQKLDLAIQELIETTDNFFINDKYYGIECA
                     FILDHALNIKMHFFNKYPAFAPPHLRGVENYDRIIHIRENNPEDKLEQISPLKD"
                     /name="hypothetical protein"
     gene            2905..3261
                     /locus_tag="M1S18_RS19140"
                     /old_locus_tag="M1S18_19140"
     CDS             2905..3261
                     /locus_tag="M1S18_RS19140"
                     /old_locus_tag="M1S18_19140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005194067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000269904.1"
                     /translation="MWTVITTDLFNEWLEQQDEATQEKVLAALVVLQQQGPSLGRPLVD
                     TVYDSKFTNMKELRVQHRGKPLRAFFAFDPLRQAIVLCIGDKSNKKRFYTEMLAIADEQ
                     YALHLSTLGDQSNG"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            3254..3556
                     /locus_tag="M1S18_RS19145"
                     /old_locus_tag="M1S18_19145"
     CDS             3254..3556
                     /locus_tag="M1S18_RS19145"
                     /old_locus_tag="M1S18_19145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_001129974.1"
                     /translation="MAKSLQELLASRSPESQARIQKMADELLLESQLHLIREELEISQK
                     ELAATLGIKQPSLSAIENRGHDLKISTMKKYVEAMGGKLRIDVELPTGKHIGFNV"
                     /name="helix-turn-helix domain-containing protein"
     gene            3549..3758
                     /locus_tag="M1S18_RS19150"
                     /old_locus_tag="M1S18_19150"
     CDS             3549..3758
                     /locus_tag="M1S18_RS19150"
                     /old_locus_tag="M1S18_19150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000069474.1"
                     /translation="MSNNKPLKNSTKLLVNLDKFIFLVNAADSLEEIEIIRDLCCEYFS
                     HCKRPSYYIDIFDNAYWIKYYEIA"
                     /name="hypothetical protein"
     gene            complement(4084..4545)
                     /locus_tag="M1S18_RS19155"
                     /old_locus_tag="M1S18_19155"
     CDS             complement(4084..4545)
                     /locus_tag="M1S18_RS19155"
                     /old_locus_tag="M1S18_19155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004781077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DIP1984 family protein"
                     /protein_id="WP_000761346.1"
                     /translation="MKLAEALLLRSDQQKKIISLKQRINANVLVQDGDQPSEDPNELLK
                     QVFSLIQEFQKLSYAIHETNALTKLNDGRSLLALLTLRDEFVEQHKTLTAAISNTSRES
                     DRYSTREIKWHKVIPVSSLQKQADDISLKLRDLNVLIQSTNWKIDLIEA"
                     /name="DIP1984 family protein"
     gene            complement(4848..7250)
                     /gene="znuD2"
                     /locus_tag="M1S18_RS19160"
                     /old_locus_tag="M1S18_19160"
                     /pseudo=""
     CDS             complement(4848..7250)
                     /gene="znuD2"
                     /locus_tag="M1S18_RS19160"
                     /old_locus_tag="M1S18_19160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932945.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor ZnuD2"
                     /name="znuD2"
     gene            complement(7389..7682)
                     /locus_tag="M1S18_RS19165"
                     /old_locus_tag="M1S18_19165"
                     /pseudo=""
     CDS             complement(7389..7682)
                     /locus_tag="M1S18_RS19165"
                     /old_locus_tag="M1S18_19165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005065064.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="BrnA antitoxin family protein"
                     /name="BrnA antitoxin family protein"
     gene            complement(7669..7952)
                     /locus_tag="M1S18_RS19170"
                     /old_locus_tag="M1S18_19170"
                     /pseudo=""
     CDS             complement(7669..7952)
                     /locus_tag="M1S18_RS19170"
                     /old_locus_tag="M1S18_19170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019383542.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="BrnT family toxin"
                     /name="BrnT family toxin"
     gene            complement(8243..8554)
                     /locus_tag="M1S18_RS19175"
                     /old_locus_tag="M1S18_19175"
     CDS             complement(8243..8554)
                     /locus_tag="M1S18_RS19175"
                     /old_locus_tag="M1S18_19175"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_249377535.1"
                     /translation="MLILGKLNSIGDTNGQKIEEKTKDINEKIQKLDLAIQELIETTDN
                     FFINDKYYGIECAFILDHALNIKMHFFNKYPAFAPPHLRGVEIMIELYILEKIILKIS"
                     /name="hypothetical protein"
     gene            complement(8723..9240)
                     /locus_tag="M1S18_RS19180"
                     /old_locus_tag="M1S18_19180"
                     /pseudo=""
     CDS             complement(8723..9240)
                     /locus_tag="M1S18_RS19180"
                     /old_locus_tag="M1S18_19180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839337.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication DNA-binding protein"
                     /name="plasmid replication DNA-binding protein"
     gene            complement(9318..10251)
                     /gene="repM"
                     /locus_tag="M1S18_RS19185"
                     /old_locus_tag="M1S18_19185"
                     /pseudo=""
     CDS             complement(9318..10251)
                     /gene="repM"
                     /locus_tag="M1S18_RS19185"
                     /old_locus_tag="M1S18_19185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005065049.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepM"
                     /name="repM"
     gene            complement(10849..12017)
                     /locus_tag="M1S18_RS19195"
                     /old_locus_tag="M1S18_19195"
                     /pseudo=""
     CDS             complement(10849..12017)
                     /locus_tag="M1S18_RS19195"
                     /old_locus_tag="M1S18_19195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002011489.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /name="MobA/MobL family protein"
     gene            12321..13080
                     /locus_tag="M1S18_RS19200"
                     /old_locus_tag="M1S18_19200"
                     /pseudo=""
     CDS             12321..13080
                     /locus_tag="M1S18_RS19200"
                     /old_locus_tag="M1S18_19200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017393773.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            13197..13496
                     /locus_tag="M1S18_RS19205"
                     /old_locus_tag="M1S18_19205"
     CDS             13197..13496
                     /locus_tag="M1S18_RS19205"
                     /old_locus_tag="M1S18_19205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000358348.1"
                     /translation="MDKKIEEKTKDINEKIQKLDLAIQELIETTDNFFINDKYYGIECA
                     FILDHALNIKMHFFNKYPAFAPPHLRGVENYDRIIHIRENNPEDKLEQISPLKD"
                     /name="hypothetical protein"
     gene            14061..14417
                     /locus_tag="M1S18_RS19210"
                     /old_locus_tag="M1S18_19210"
     CDS             14061..14417
                     /locus_tag="M1S18_RS19210"
                     /old_locus_tag="M1S18_19210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005194067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000269904.1"
                     /translation="MWTVITTDLFNEWLEQQDEATQEKVLAALVVLQQQGPSLGRPLVD
                     TVYDSKFTNMKELRVQHRGKPLRAFFAFDPLRQAIVLCIGDKSNKKRFYTEMLAIADEQ
                     YALHLSTLGDQSNG"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            14410..14712
                     /locus_tag="M1S18_RS19215"
                     /old_locus_tag="M1S18_19215"
     CDS             14410..14712
                     /locus_tag="M1S18_RS19215"
                     /old_locus_tag="M1S18_19215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_001129974.1"
                     /translation="MAKSLQELLASRSPESQARIQKMADELLLESQLHLIREELEISQK
                     ELAATLGIKQPSLSAIENRGHDLKISTMKKYVEAMGGKLRIDVELPTGKHIGFNV"
                     /name="helix-turn-helix domain-containing protein"
     gene            14705..14914
                     /locus_tag="M1S18_RS19220"
                     /old_locus_tag="M1S18_19220"
     CDS             14705..14914
                     /locus_tag="M1S18_RS19220"
                     /old_locus_tag="M1S18_19220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000069474.1"
                     /translation="MSNNKPLKNSTKLLVNLDKFIFLVNAADSLEEIEIIRDLCCEYFS
                     HCKRPSYYIDIFDNAYWIKYYEIA"
                     /name="hypothetical protein"
     gene            complement(15240..15702)
                     /locus_tag="M1S18_RS19225"
                     /old_locus_tag="M1S18_19225"
                     /pseudo=""
     CDS             complement(15240..15702)
                     /locus_tag="M1S18_RS19225"
                     /old_locus_tag="M1S18_19225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004781077.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DIP1984 family protein"
                     /name="DIP1984 family protein"
     gene            complement(16007..18419)
                     /gene="znuD2"
                     /locus_tag="M1S18_RS19230"
                     /old_locus_tag="M1S18_19230"
                     /pseudo=""
     CDS             complement(16007..18419)
                     /gene="znuD2"
                     /locus_tag="M1S18_RS19230"
                     /old_locus_tag="M1S18_19230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932945.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor ZnuD2"
                     /name="znuD2"
     gene            complement(18547..18861)
                     /locus_tag="M1S18_RS19235"
                     /old_locus_tag="M1S18_19235"
     CDS             complement(18547..18861)
                     /locus_tag="M1S18_RS19235"
                     /old_locus_tag="M1S18_19235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006582675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnA antitoxin family protein"
                     /protein_id="WP_001983304.1"
                     /translation="MSMVRYSHKELNEKFGEKQDAEIQRLLAKGTVPDDQLDLSDIPEI
                     TDWSNAVRQNQFYRPVKQQTSIRLDADVLAWFKAQGKGYQTRMNEILRDAMLKELKNHQ
                     "
                     /name="BrnA antitoxin family protein"
     gene            complement(18848..19135)
                     /locus_tag="M1S18_RS19240"
                     /old_locus_tag="M1S18_19240"
     CDS             complement(18848..19135)
                     /locus_tag="M1S18_RS19240"
                     /old_locus_tag="M1S18_19240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019383542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnT family toxin"
                     /protein_id="WP_000438827.1"
                     /translation="MEQYFEWDEAKNRKNQKKHDISFETASLVFEDPLRISIQDRYTNG
                     EERWQTIGRVKGVLMLLVAHTIFDEDDCEIIRIISARQVTKAERNKYEHG"
                     /name="BrnT family toxin"
     gene            complement(19403..19702)
                     /locus_tag="M1S18_RS19245"
                     /old_locus_tag="M1S18_19245"
     CDS             complement(19403..19702)
                     /locus_tag="M1S18_RS19245"
                     /old_locus_tag="M1S18_19245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000358348.1"
                     /translation="MDKKIEEKTKDINEKIQKLDLAIQELIETTDNFFINDKYYGIECA
                     FILDHALNIKMHFFNKYPAFAPPHLRGVENYDRIIHIRENNPEDKLEQISPLKD"
                     /name="hypothetical protein"
     gene            complement(19819..20580)
                     /locus_tag="M1S18_RS19250"
                     /old_locus_tag="M1S18_19250"
     CDS             complement(19819..20580)
                     /locus_tag="M1S18_RS19250"
                     /old_locus_tag="M1S18_19250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017393773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000425105.1"
                     /translation="MEMEKAKKRGRPAQLLQIAELHAFVEFLEQQEQLSDLQSQVLKAL
                     NSVDCNFEGLTQTDQVLVKEALKPYREHLKLKLLFEELNNLPLKTEYEQKFLDLYELFQ
                     KNALDQMELNILKTLATRYLNFKAQKLEYSDLELYLSQLQKKDAGKKRKAENQRKFELG
                     GAVLVAFKKLNIDISNDTPQQITNRIVNTTKFHNEVRKSLIFKDVKTYENEYFKANKLF
                     IQVLEGLHTWQKGGELLSVIEIKKALEKGEE"
                     /name="hypothetical protein"
     gene            20885..22056
                     /locus_tag="M1S18_RS19800"
                     /pseudo=""
     CDS             20885..22056
                     /locus_tag="M1S18_RS19800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002011489.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /name="MobA/MobL family protein"
     Typing          300..1234
                     /name="rep_cluster_1226"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(9319..10251)
                     /name="rep_cluster_1226"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.786"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(10853..11196)
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(11215..12017)
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.776"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          21311..22053
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.194"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 agcgtagcga aaacataggg caatttttca ttcattgggc ttttaattat ttttaatctt
       61 ttaaatgctt ttaaataagc tgtaaacctt tatttataat agtttcatag ttaataaaac
      121 taggtttatc gacccataaa actaggttta tcgacccata aaactaggtt tatcgaccca
      181 taaaactagg tttatcgacc ttaaagctag gtttatcgac ccataattaa gttaatttac
      241 aactcaattg aaatagtcta ttgtacaacc tagtttaatt ataaatttat tattagaaat
      301 gagtgaatta atcgtaaagg ataatgctct aattcaagca agttatacct tagatacagt
      361 tgaacaaaga ctgatcctat tagccattgc tgaagctcga gaaactggac atgggataac
      421 tgaaaatagt cttttagaag tacatgcaag tagttatata aatactttta atgtcgagaa
      481 acataccgct tataccgtac tcagagaggc atctaaaagc ttatttgatc gctatgtcac
      541 ataccatgac attaatccta agacaggtaa ggatcgtagc tttcattgtc gttgggtcga
      601 caaaattggg tatgaatctc aatcaggaat tattttccta cgattcaccc aagatatcgt
      661 tccactcata actcgacttg aagaaaattt cactaaatat gaattgcagc aggtttctag
      721 gttaagtagc tcatatgcta ttcggctata cgagctatta attcaatgga gatctgccgg
      781 aaaaacgcca ctttttgatc tatctatctt tagacaacaa cttggtgtca aacctcatca
      841 atacaaaaca atgagtaact ttaaaacata tgttttagat tttgctctta agcaggtaaa
      901 tgagttaacc gatataacag ctaaatatga gcaacataaa aaagggcgtt ctatttcagg
      961 tttttcattc actttcaaac agaaaaaaat gagtaatctg ccaataaaaa ataagcgtga
     1021 cccagacact atagatattt tctcaaaaat gacagatgct caacgccatc tgttttccca
     1081 caaactgtca gaacttcctg aaatgggaaa gtattctcat ggtacagaaa gctatccgca
     1141 attcgctgta cgcattgcag aaatgcttca aaacccagaa aagtttaaag aactctatcc
     1201 ttatctccaa aaagtaggct tcaaagctgc atagaagata gacttgctga tttgtctatt
     1261 agacagtcta atagacacta attttttaca agattaggca gagatttaca catgaaaagc
     1321 cttacagttc ttgagctttc taagctttac aatattaatc gacaaaccat ttacaacaat
     1381 ataaagaaag gtattttaag taaaaattct gacaataaga ttgatcttgc agaagcgatc
     1441 cgggtatttg gtgagccagt acaaaaacag agtgtaaaag aaactgtaaa agtagacagt
     1501 ccaacttcgg cagaagtttt actccttaga cagcagatag acctactaaa aaatcagcta
     1561 gatgatgcaa aaaatagaga aagcttctat caaaatcaaa ttgaaactat gcaacgccta
     1621 ttggaagctc caaaaaccaa tacaacacaa tctgatgatc ctggatcaac acaggcagaa
     1681 tccacagtag aagaaaaaga ggacgtcata gctatgcctc ctaaggagtc agaggttatc
     1741 gagaataagc gtattccagt ccctgaacat attgagccag aaccagaaaa aaggggcttc
     1801 tggagccgtt ttttcaagcc ctatggatga taggactatt taatcagact aatcaaaacc
     1861 gtggaacaat gatcaataat tgatcgtgaa acataaaaaa tcactaaaac agcctgagcg
     1921 tgactgctta ggctgttttt acatccataa gacattgttt taaaatgctt tttacaaaga
     1981 atttcgtata aggtgtatta tgttaatttt agggaaactt aattctatag gtgataccaa
     2041 tggacaaaaa gatagaagag aaaactaaag atattaatga aaaaattcaa aaattggatt
     2101 tagctattca agaactaata gaaactacag acaatttttt tattaatgat aagtactatg
     2161 gaattgaatg tgcttttatt ttagaccatg cactaaatat taaaatgcac tttttcaaca
     2221 agtatccagc atttgcacca cctcacttac gaggagtaga aaattatgat cgaattatac
     2281 atattagaga aaataatcct gaagataagc tagaacaaat ttctcctctt aaagactaaa
     2341 ttttctaatc ttgtacttag agtcccctac tatttaacat aatggatatt atgcgaaatg
     2401 gatctttaag attactttaa gatcagtagc ttacattgag tcataccctc tggaacgacc
     2461 tcgttcaacc gacttagaaa caagtcggtt tttttatgct caattttgat acttcttgcc
     2521 aataaaattg tttaaaaaat aatcaaaaat agcaattcca tagagtttat aagctttttt
     2581 acccaaaaga atccactatt tctgtggata accactggga taaattttga ttattttttg
     2641 tacgttttgg cttacagcgt ttcacgaaat tgtctgtatc tatcccccga tgaagctctt
     2701 atgatcgatc tatatggaca ggatgttcaa tgacttaaaa caacaataat aatcagtcag
     2761 gcaccatgac catcaggtag tcagccctac ctatgcgctc cataccgaaa aatcccgaca
     2821 tgacgtcggg attttttatt gccatttgca aagtcattca atcagattta atatatagac
     2881 tgtaatctat attgtgattg taatatgtgg acagtcatta caacggatct gtttaatgaa
     2941 tggcttgaac agcaagatga agcaacacaa gagaaagtct tagctgcatt ggttgttcta
     3001 caacagcaag ggcctagttt aggtcgtcct ttagtagata ccgtctacga ttctaaattt
     3061 accaatatga aggaactacg tgttcagcat cgtggtaaac cgttaagggc attttttgca
     3121 ttcgatcccc taagacaagc gattgtgctg tgtattggtg ataagagtaa taaaaagcgt
     3181 ttttatacag agatgctagc aattgcagat gagcaatacg cacttcatct ctcaacttta
     3241 ggagatcaat ctaatggcta agagcttaca agaattattg gctagtcgct ctccagagag
     3301 tcaagctcgt attcaaaaaa tggctgatga attactttta gaaagtcagc ttcaccttat
     3361 ccgagaagag ttagaaattt cccagaaaga actagctgca acccttggaa ttaaacagcc
     3421 gtcattatca gcaatcgaaa atcgtggtca tgatcttaaa atttcaacga tgaaaaagta
     3481 tgttgaagca atgggtggaa aacttcgtat tgatgtagag cttccaacag gaaaacacat
     3541 agggttcaat gtctaataat aaacctttga aaaatagtac taaattactt gttaacttag
     3601 acaagtttat atttttagtc aatgctgccg atagcctaga agaaattgaa attattagag
     3661 atttatgctg tgaatatttt tcacattgta agaggccaag ctattacatt gatatttttg
     3721 acaatgctta ttggataaaa tattacgaaa tagcttaatc cttctagatt cgcataagag
     3781 attttatgtt aaatgccgaa atgaattaaa aatagaaatg tagttgagct gatgcttgct
     3841 catttcttta tttttagtaa ttgaggtgaa catactgtca gtacatggta gttataagta
     3901 acgtgtaact ttgtttgcac aaagatttga gttatgccaa gtgatggatt gatttgtact
     3961 taaaatttta agcttatcca cttgctttgc aagccactac actttattta caatcctatg
     4021 ttgtggaagt aagggatctt gtactcgccc agtatgttca acttgattat atctaaagga
     4081 ctattaggct tcaatcaaat caattttcca attagtcgac tgaattaaca cgtttaaatc
     4141 acgtaattta agactaatat catcagcttg tttttgtaat gatgaaactg gaataacttt
     4201 atgccacttt atttcccgcg tactataacg atcagattca cgagatgtat tacttattgc
     4261 tgcagttagg gttttgtgct gttctacaaa ttcatcacgc aaagtcaata aagcaagtag
     4321 agaacggcca tcatttaatt ttgttaaagc attagtttca tgaattgcat aacttaattt
     4381 ttgaaattct tgaattaaag aaaatacttg ttttagtagt tcatttggat cttcagatgg
     4441 ttgatcacca tcttgtacca atacatttgc attgatacgt tgttttagtg aaataatttt
     4501 tttttgttga tcacttcgaa gtaagagagc ttctgctaat ttcatttttc acctattaac
     4561 caattagaat taagttttaa acagcttata tcctcattct ttaaagatca aaaaaattgc
     4621 tttttatcta gctaaaaggt gtctacaaaa tcggtggcta ttcagtgctg aaaggctgcc
     4681 gacacataaa gtgacccaga ttgaagagtt actgccacac tgctggaaac ctaaatcgaa
     4741 ttaaaaatag gtatgggatt cagcggacgc ttaccttaat tattaatcta atcattttat
     4801 aagaaaaatc ttctaagaaa ttttcttaga agattacagt atcttatcta gaaattaaga
     4861 tttaagccta aactaaaatt tcttccaatt tggggaatat atggcaaaaa tgtttcatgg
     4921 gcatagactt tctgatcaag taaattattc gctttaaaga atatcatatt ctgtgtgaga
     4981 tagcttattt ttatatgcta aagtcatatt aagcatatta taacctgatg taacctgctc
     5041 aaatttagaa atattatctt ttaaagactc gataatattc tatttcacct ttaagcgatt
     5101 catcaaaatc agcttttagt cgtgtaccca aacgagcagg aggtaatcta ggagtgtaac
     5161 gatccttttg gggagctaaa gtcggttctc tattccagat atcgtatgca attacagcat
     5221 caggtaaatt tgttaaacgg cctttcacat aatctccaaa agagagccgt gataaacaga
     5281 attaaattga taccctatgt tgccctctaa tccataaaaa ttagcagcag actggctata
     5341 atgattaata cgtagtgtat gctgatctct aacttttgta gttcctaaaa cttcattgag
     5401 tgtctgtaaa tatatatagt tatcaaaatc ataatagtaa gtactgattt gataatcaag
     5461 taaatcatcc ttataggcca gactgatttc taaattattg gatttctctt ttcttagaaa
     5521 gcggttacct atttcaaaag aattagtagc gagatgcata ccatgagtat acatttcttg
     5581 tgcattaggt aatctttctt gatgtgtacc tgttaatgat aagatataat ttggagcaaa
     5641 tctccagtgg actgtacctg cataagaaaa agctgtttct ttgttaggtt gaacagcttc
     5701 taaaatagat tttaaatttt gagccctgat tttattattt ttttctacat aaggactgtt
     5761 atatttatta ggccaaggtt tcattgaatc tttaattttt tctatatcat aatccatact
     5821 aactttctgc ttttctatac gagcacctag ttcgaaagta aagtcgttcc agttatattt
     5881 ttctaggcca aatacactaa agtttttagt gacatttcga tttaatagct gctgattatc
     5941 tagataggtg gtatggccat tcttgagaat ggactggtga taaagcacta ttatcctgtt
     6001 ccaaatttag ccccaagata ccggttaatt cccctaatgg ctgatgtgat aactctatgc
     6061 ggcctacttt tcctgtattt ttaaaaaagt tagtaatctt atctccctcg agttcattgt
     6121 gaaaataatc tatataactc aatgaggtac gaattttgtc aataccggta aatggttgag
     6181 tgaattctcc acgcacatca taacgtcgag tatttaaatc aatataagga gcattatgag
     6241 agaaattagt ttcatgaata tgattatgct gatgacaatc aggacgtgga tttatgtaat
     6301 taatatcttg ctcatccatc aattgaggat aatataaaga taatttttta atccactaat
     6361 tcgtgaatcg ataccgattg cagaggcaac cacaaccttc atataaatgg ctatgggctg
     6421 gtaaaccata ttcatcatga cgatgtgtat aagaaactcc taaataagta ttatcgtcta
     6481 tccaggataa tccaagcgta cctactctcg actctgccca gctttctggt aaatatttta
     6541 aatttttata aatactgttt tggttttcaa gatcttctaa agaattataa gagctagact
     6601 ggtaatgagg agttttatag ttaccagcat tacgatataa cccttctgcc cgtaaagcta
     6661 catgtgggct taagccaact gttacacctg ctgtggtcaa cttctcatta ctgccagtat
     6721 taaaacgtaa tgtagtatac cctctaatcc gtcttgaggc atttgggttg gaattttata
     6781 gtcaatgaca ttgactaccc ctgccgcact atttgaacta tacaaaaggg tacttgcacc
     6841 acgtataatt tcaatagact tagctaaact tggttcaact gtgacagcgt gatctggaga
     6901 catattagac atatccaaca cgtcagcatt attctgtaaa actttaatac gttttccttc
     6961 ctgcccacga ataataggag tagatgctcc acctccatat tgattagaat gaattcctaa
     7021 ttccgtaccc aaggcatccc ctagagttgt cgaacgctgt ttaagtttac tagtatcaat
     7081 aactgattac taacatttag aactttgcct aacagctcag accctaactc atcagattgt
     7141 gcagttaata ctattgtatt taaggtagta acaggccctt cagctgccaa taaaattttc
     7201 gaggccctaa agtaattaaa gctaaaaaat agtttacttt tatttagcat aaaacaacca
     7261 aatttaatgt tatattataa tataacactt aaaaattata aaatctacta tttaaatttt
     7321 tgaatggtaa tccccctaaa aatgaagtca aaaatgggag cctaagctcc cattcttatt
     7381 gatgattttt aattctttag catagcatct cgtaaaattt cattcatacg tgtttgataa
     7441 cctttgcctt ggcttgaacc aagcaagtac atcagcatct aaccgaattg aagttgttgc
     7501 tttactgggc ggtaaaattg attttggcgt acagcattgc tccagtctgt aatttcagga
     7561 atatctgata gatctagctg atcatcagga accggccttt agcaagcaag cgttgaattt
     7621 cagcatcttg cttctcacca aatttccttc agctctttgt gtgagtatct aaccatgctc
     7681 atttgtttcg ctccgcttta gtgacttgct tgcactaatg attcggatga tttcacagtc
     7741 atcttcatca aaaatggtgt gagccaccaa taacattagt acgcctttaa ctcgtccaat
     7801 ggtttgccaa cgttcttcac cattagtata tctgtcttgg attgagatcc gtaatggatc
     7861 ttaaaaacaa ggcttgcagt ttcgaaagag atatcatgct ttttctgatt ctttcgattc
     7921 ttagcctcat cccattcaaa atactgttcc ataaaaaata ttcaaatttg tatatacaat
     7981 aatgtatcac gaaattgtat cactcaagtt gagaagcgta attttagtca gatttattgg
     8041 caaaaactat caaaatcgat cataaaaaag ccgacttgtt tcaaagtcgg cttttgggca
     8101 tttttggatt tttatatttt tattaagtag ttgatattta aattaatata caagtgtact
     8161 tcgtataata tccattatgt taaatagtag gggactctaa gtacagatta gaaaatttag
     8221 tctttaagag gagaaatttg ttctagctta tcttcaggat tattttctct aatatgtata
     8281 attcgatcat aatttctact cctcgtaagt gaggtggtgc aaatgctgga tacttgttga
     8341 aaaagtgcat tttaatattt agtgcatggt ctaaaataaa agcacattca attccatagt
     8401 acttatcatt aataaaaaaa ttgtctgtag tttctattag ttcttgaata gctaaatcca
     8461 atttttgaat tttttcatta atatctttag ttttctcttc tatcttttgt ccattggtat
     8521 cacctataga attaagtttc cctaaaatta acataataca ccttatacga aattctttgt
     8581 aaaaagcatt ttaaaacaat gtcttatgga tgtaaaaaca gcctaagcag tcacgctcag
     8641 gctgttttag tgatttttat gtttcacgat caattattga tcattgttcc acggttttga
     8701 ttagtctgat taaatagtcc tatcatccat agggcttgaa aaaacggctc cagaagccct
     8761 tttttctggt tctggctcaa tatgttcagg gactggaata cgcttattct cgataacctc
     8821 tgactcctta ggaggcatag ctatgacgtc ctctttttct tctactgtgg attctgcctg
     8881 tgttgatcca ggatcatcag attgtgttgt attggttttt ggagcttcca ataggcgttg
     8941 catagtttca atttgatttt gatagaagct ttctctattt tttgcatcat ctagctgatt
     9001 ttttagtagg tctatctgct gtctaaggag taaaacttct gccgaagttg gactgtctac
     9061 ttttacagtt tcttttacac tctgtttttg tactggctca ccaaataccc ggatcgcttc
     9121 tgcaagatca atcttattgt cagaattttt acttaaaata cctttcttta tattgttgta
     9181 aatggtttgt cgattaatat tgtaaagctt agaaagctca agaactgtaa ggcttttcat
     9241 gtgtaaatct ctgcctaatc ttgtaaaaaa ttagtgtcta ttagactgtc taatagacaa
     9301 atcagcaagt ctatcttcta tgcagctttg aagcctactt tttggagata aggatagagt
     9361 tctttaaact tttctgggtt ttgaagcatt tctgcaatgc gtacagcgaa ttgcggatag
     9421 ctttctgtac catgagaata ctttcccatt tcaggaagtt ctgacagttt gtgggaaaac
     9481 agatggcgtt gagcatctgt catttttgag aaaatatcta tagtgtctgg gtcacgctta
     9541 ttttttattg gcagattact catttttttc tgtttgaaag tgaatgaaaa acctgaaata
     9601 gaacgccctt ttttatgttg ctcatattta gctgttatat cggttaactc atttacctgc
     9661 ttaagagcaa aatctaaaac atatgtttta aagttactca ttgttttgta ttgatgaggt
     9721 ttgacaccaa gttgttgtct aaagatagat agatcaaaaa gtggcgtttt tccggcagat
     9781 ctccattgaa ttaatagctc gtatagccga atagcatatg agctacttaa cctagaaacc
     9841 tgctgcaatt catatttagt gaaatttttt caagtcgagt tatgagtgga acgatatctt
     9901 gggtgaatcg taggaaataa ttcctgattg agattcatac ccaattttgt cgacccaacg
     9961 acaatgaaag ctacgatcct tacctgtctt aggattaatg tcatggtatg tgacatagcg
    10021 atcaaataag cttttagatg cctctctgag tacggtataa gcggtatgtt tctcgacatt
    10081 aaaagtattt atataactac ttgcatgtac ttctaaaaga ctattttcag ttatcccatg
    10141 tccagtttct cgagcttcag caatggctaa taggatcagt ctttgttcaa ctgtatctaa
    10201 ggtataactt gcttgaatta gagcattatc ctttacgatt aattcactca tttctaataa
    10261 taaatttata attaaactag gttgtacaat agactatttc aattgagttg taaattaact
    10321 taattatggg tcgataaacc tagctttaag gtcgataaac ctagttttat gggtcgataa
    10381 acctagtttt atgggtcgat aaacctagtt ttatgggtcg ataaacctag ttttattaac
    10441 tatgaaaact attataaata aaggtttaca gcttatttaa aagcatttaa aagattaaaa
    10501 ataattaaaa gcccaatgaa tgaaaaattg ccctatgttt tcgctacgct caaactctat
    10561 tgaacttcgc ttacgctcag ttcgaagggg caatttttgg gttaatctcg tgataacttc
    10621 aaaaaagcaa aagcaactcg gaattcgctt cgctcataag ttttttatac tcgcttcgct
    10681 cgacctagat gcaaattaaa tctgttcgca ccctccggga tgctctgtat ctcagtctca
    10741 gcagcaaagg ggagtttgta atcagggaaa aagcatggca aaaattttaa ttgtgtctgt
    10801 tcgctcgtag acactcgctc tgtaaacttt ggataaaacc aactgagctt aaaaaccagg
    10861 gccaccgtaa tcataatcat cagctttagg ttgtactggt tctgattgag tgcgtttggg
    10921 aggcgtattt tgtatcggta atacgtattc aggaagtgaa tgcacctcga actcaaaaca
    10981 tggggtactg ttacgtcttg agtcttctag tttttcattc atttcgtaga tggaccaagc
    11041 ttcttgttta agtatagggc cttggttttt gataatttca ttcaaatcat tttttagttt
    11101 gtccttattt gttgcattct tgattaagta attcaggtaa tacatgactt ccaatgatga
    11161 aaatgggttg ttttcagcac tataaaaata ttcatgttgt tgatctaatt gctttggcgt
    11221 tcttcgagtt ctcgttcttg ctggttgtgt tctctgattt tttggatttg ggcgagatat
    11281 tccgctgtcg cattttgttg tccaacgcct agttttggct ctggaaggta tagcgtgctg
    11341 tggatctcgt tatatttttc atagctgtct gctgaaacct gatttttgat ggtgatgtct
    11401 tggccatcca gtgtgtaggt gacggtcggg cagtgctgtg caagggcatc attcaaatga
    11461 ttttcccatt gttttcggat atagatcaaa aaagtggaat agtcttcatg gccatcttga
    11521 agttggattt ttttggcacc gcctttggct ggatcttgag ggttatagcg tttgaagtac
    11581 tgttctgcgc tgcgttcaat gccgtcatcc gcttttagcg agaacatcag atgacaatga
    11641 ggctgatctt cgccactgat acgtgatttt acgttgtgta tggcgtatga gtgcggatat
    11701 tgctgtggaa ctatatgttt gtctaaaaac gtctctatga gcgttttacg ctgttctgac
    11761 gtgaactcat tcggtagggc aatttcatac tccatgtagg ccttggcatt ggctcgttca
    11821 tacgtatctg ctgcctgcca aaaatcaatg ggatctttta caaaggcagg catacatcga
    11881 ccaggttcaa tatgttctat ggtctcattg ctggttttgc ggatgccttc atactgcatc
    11941 agccgggaaa tgtagagata atggccggtc gcatagccct tatttttgct tttgacgctg
    12001 aagtggtagc tggccatgtt cacctctgct gggttgtggg ttcggttttt atgcagtgaa
    12061 acggaatgaa aaccgcccgg atttgaaatg cctgtatggc tgaaaaatcc ggttgaaggg
    12121 ggtcaagggg aagcgcccca ttgcgtacta gtttctccga tgaggagaaa actgtcaagt
    12181 gcgaattatt taatataaaa ataaaatttc ttgaaaagaa ttttattttt atattaaata
    12241 attattttca gactgccctc tttaaatatg gtaaaaccat atttaaagag gttgcagttc
    12301 tgaaaatttg gcggcagatg atggaaatgg aaaaagcaaa aaagcgtggt cgacctgctc
    12361 agttgttaca gattgctgag ttacatgcat ttgtagagtt tttagaacag caagaacagc
    12421 tttctgatct tcaatctcaa gtgttaaagg ctttaaatag tgttgattgt aattttgagg
    12481 gctaactcag acagatcagg ttctggtcaa agaggcttta aaaccttatc gtgaacatct
    12541 gaagttgaaa ttgctgtttg aagagttgaa taatctgcct cttaaaaccg agtatgaaca
    12601 gaagttttag atctgtatga actttttcaa aagaatgcac tagatcagat ggaactaaat
    12661 attttaaaaa ccttggcgac acggtatctg aattttaaag cgcaaaagct tgaatacagt
    12721 gatttagaat tgtatttgag tcagctacag aagaaggatg ctgggaaaaa acgcaaagct
    12781 gaaaatcaac gtaaatttga attaggtggt gctgttcttg tcgcatttaa gaaactcaat
    12841 attgatatta gcaatgatac tcctcaacag attaccaatc ggattgtgaa tacgacaaag
    12901 tttcataatg aagtacgtaa atctttaatt tttaaagatg ttaagacata tgaaaatgaa
    12961 tattttaaag caaataaact ttttattcag gtgttagaag gattacatac ctggcaaaag
    13021 ggcggagaat tattgtcagt aattgaaatt aaaaaggcct tagaaaaagg cgaagagtag
    13081 tttatttagc agggatttta gagaagttgg acatttctat tttgggctta cattggaatt
    13141 tcgcataagg tgtattatgt taattttagg gaaacttaat tctataggtg ataccaatgg
    13201 acaaaaagat agaagagaaa actaaagata ttaatgaaaa aattcaaaaa ttggatttag
    13261 ctattcaaga actaatagaa actacagaca atttttttat taatgataag tactatggaa
    13321 ttgaatgtgc ttttatttta gaccatgcac taaatattaa aatgcacttt ttcaacaagt
    13381 atccagcatt tgcaccacct cacttacgag gagtagaaaa ttatgatcga attatacata
    13441 ttagagaaaa taatcctgaa gataagctag aacaaatttc tcctcttaaa gactaaattt
    13501 tctaatcttg tacttagagt cccctactat ttaacataat ggatattatg cgaaatggat
    13561 ctttaagatt actttaagat cagtagctta cattgagtca tacctctgga acgacctcgt
    13621 tcaaccgact tagaaacaag tcggtttttt tatgctcaat tttgatactt cttgccaata
    13681 aaattgttta aaaaataatc aaaaatagca attccataga gtttataagc ttttttaccc
    13741 aaaagaatcc actatttctg tggataacca ctgggataaa ttttgattat tttttgtacg
    13801 ttttggctta cagcgtttca cgaaattgtc tgtatctatc ccccgatgaa gctcttatga
    13861 tcgatctata tggacaggat gttcaatgac ttaaaacaac aataataatc agtcaggcac
    13921 catgaccatc aggtagtcag ccctacctat gcgctccata ccgaaaaatc ccgacatgac
    13981 gtcgggattt tttattgcca tttgcaaagt cattcaatca gatttaatat atagactgta
    14041 atctatattg tgattgtaat atgtggacag tcattacaac ggatctgttt aatgaatggc
    14101 ttgaacagca agatgaagca acacaagaga aagtcttagc tgcattggtt gttctacaac
    14161 agcaagggcc tagtttaggt cgtcctttag tagataccgt ctacgattct aaatttacca
    14221 atatgaagga actacgtgtt cagcatcgtg gtaaaccgtt aagggcattt tttgcattcg
    14281 atcccctaag acaagcgatt gtgctgtgta ttggtgataa gagtaataaa aagcgttttt
    14341 atacagagat gctagcaatt gcagatgagc aatacgcact tcatctctca actttaggag
    14401 atcaatctaa tggctaagag cttacaagaa ttattggcta gtcgctctcc agagagtcaa
    14461 gctcgtattc aaaaaatggc tgatgaatta cttttagaaa gtcagcttca ccttatccga
    14521 gaagagttag aaatttccca gaaagaacta gctgcaaccc ttggaattaa acagccgtca
    14581 ttatcagcaa tcgaaaatcg tggtcatgat cttaaaattt caacgatgaa aaagtatgtt
    14641 gaagcaatgg gtggaaaact tcgtattgat gtagagcttc caacaggaaa acacataggg
    14701 ttcaatgtct aataataaac ctttgaaaaa tagtactaaa ttacttgtta acttagacaa
    14761 gtttatattt ttagtcaatg ctgccgatag cctagaagaa attgaaatta ttagagattt
    14821 atgctgtgaa tatttttcac attgtaagag gccaagctat tacattgata tttttgacaa
    14881 tgcttattgg ataaaatatt acgaaatagc ttaatccttc tagattcgca taagagattt
    14941 tatgttaaat gccgaaatga attaaaaata gaaatgtagt tgagctgatg cttgctcatt
    15001 tctttatttt tagtaattga ggtgaacata ctgtcagtac atggtagtta taagtaacgt
    15061 gtaactttgt ttgcacaaag atttgagtta tgccaagtga tggattgatt tgtacttaaa
    15121 attttaagct tatccacttg ctttgcaagc cactacactt tatttacaat cctatgttgt
    15181 ggaagtaagg gatcttgtac tcgcccagta tgttcaactt gattatatct aaaggactat
    15241 taggcttcaa tcaaatcaat tttccaatta gtcgactgaa ttaacacgtt taaatcacgt
    15301 aatttaagac taatatcatc agcttgtttt tgtaatgatg aaactggaat aactttatgc
    15361 cactttattt cccgcgtact ataaacgatc agattcacga gatgtattac ttattgctgc
    15421 agttagggtt ttgtgctgtt ctacaaattc atcacgcaaa gtcaataaag caagtagaga
    15481 acggccatca tttaattttg ttaaagcatt agtttcatga attgcataac ttaatttttg
    15541 aaattcttga attaaagaaa atacttgttt tagtagttca tttggatctt cagatggttg
    15601 atcaccatct tgtaccaata catttgcatt gatacgttgt tttagtgaaa taattttttt
    15661 ttgttgatca cttcgaagta agagagcttc tgctaatttc atttttcacc tattaaccaa
    15721 ttagaattaa gttttaaaca gcttatatcc tcattcttta aagatcaaaa aaattgcttt
    15781 ttatctagct aaaaggtgtc tacaaaatcg gtggctattc agtgctgaaa aggctgccga
    15841 cacataaagt gacccagatt gaagagttac tgccacactg ctggaaacct aaatcgaatt
    15901 aaaaaatagg tatgggattc agcggacgct taccttaatt attaatctaa tcattttata
    15961 agaaaaatct tctaagaaat tttcttagaa gattacagta tcttatctag aaattaagat
    16021 ttaagcctaa actaaaattt cttccaattt ggggaatata tggcaaaaat gtttcatggg
    16081 catagacttt ctgatcaagt aaattattcg ctttaaagaa taaatcatat tctgtgtgag
    16141 atagcttatt tttatatgct aaagtcatat taagcatatt ataacctgat gtaacctgct
    16201 caaatttaga aatattatct tgtttaaaga ctcgataata ttctatttca cctttaagcg
    16261 attcatcaaa atcagctttt agtcgtgtac ccaaacgagc aggaggtaat ctaggagtgt
    16321 aacgatcctt ttggggagct aaagtcggtt ctctattcca gatatcgtat gcaattacag
    16381 catcaggtaa atttgttaaa cggcctttca cataatctcc aaaaagagag ccgtgataaa
    16441 cagaattaaa ttgataccct atgttgccct ctaatccata aaaattagca gcagactggc
    16501 tataatgatt aatacgtagt gtatgctgat ctctaacttt tgtagttcct aaaacttcat
    16561 tgagtgtctg taaatatata tagttatcaa aatcataata gtaagtactg atttgataat
    16621 caagtaaatc atccttatag gccagactga tttctaaatt attggatttc tcttttctta
    16681 gaaagcggtt acctatttca aaagaattag tagcgagatg cataccatga gtatacattt
    16741 cttgtgcatt aggtaatctt tcttgatgtg tacctgttaa tgataagata taatttggag
    16801 caaatctcca gtggactgta cctgcataag aaaaagctgt ttctttgtta ggttgaacag
    16861 cttctaaaat agattttaaa ttttgagccc tgattttatt atttttttct acataaggac
    16921 tgttatattt attaggccaa ggtttcattg aatctttaat tttttctata tcataatcca
    16981 tactaacttt ctgcttttct atacgagcac ctagttcgaa agtaaagtcg ttccagttat
    17041 atttttctag gccaaataca ctaaagtttt tagtgacatt tcgatttaat agctgctgat
    17101 tatctagata ggtggtatgg ccattcttga gaatggactg gtgataaagc actattatcc
    17161 tgttccaaat attgtagccc caagataccg gttaattccc ctaatggctg atgtgataac
    17221 tctatgcggc ctacttttcc tgtattttta aaaaagttag taatcttatc tccctcgagt
    17281 tcattgtgaa aataatctat ataactcaat gaggtacgaa ttttgtcaat accggtaaat
    17341 ggttgagtga attctccacg cacatcataa cgtcgagtat ttaaatcaat ataaggagca
    17401 ttatgagaga aattagtttc atgaatatga ttatgctgat gacaatcagg acgtggattt
    17461 atgtaattaa tatcttgctc atccatcaat tgaggataat ataaaagata attttttaat
    17521 ccactaattc gtgaatcgat accgattgca gaggcaccac aaccttcata taaatggcta
    17581 tgggctggta aaccatattc atcatgacga tgtgtataag aaactcctaa ataagtatta
    17641 tcgtctatcc aggataatcc aagcgtacct actctcgact ctgcccagct ttctggtaaa
    17701 tattttaaat ttttataaat actgttttgg ttttcaagat cttctaaaga attataagag
    17761 ctagactggt aatgaggagt tttatagtta ccagcattac gatataaccc ttctgcccgt
    17821 aaagctacat gtgggcttaa gccaactgtt acacctgctg tggtcaactt ctcattactg
    17881 ccagtattaa aacgtaatgt agtattaccc tctaatccgt cttgaggcat ttgggttgga
    17941 attttatagt caatgacatt gactacccct gccgcactat ttgaactata caaaagggta
    18001 cttgcaccac gtataatttc aatagactta gctaaacttg gttcaactgt gacagcgtga
    18061 tctggagaca tattagacat atccaacacg tcagcattat tctgtaaaac tttaatacgt
    18121 tttccttcct gcccacgaat aataggagta gatgctccac ctccatattg attagaatga
    18181 attcctaatt ccgtacccaa ggcatcccct agagttgtcg aacgctgttt aagtttacta
    18241 gtatcaataa actgattact aacatttaga cttttgccta acagctcaga ccctaactca
    18301 tcagattgtg cagttaatac tattgtattt aaggtagtaa caggcccttc agctgccaat
    18361 aaaattttcg aggcccctaa agtaattaaa gctaaaaata gtttactttt atttagcata
    18421 aaacaaccaa atttaatgtt atattataat ataacactta aaaatttata aaatctacta
    18481 tttaaatttt tgaatggtaa tcccccctaa aaatgaagtc aaaaatggga gcctaagctc
    18541 ccattcttat tgatgatttt ttaattcttt tagcatagca tctcgtaaaa tttcattcat
    18601 acgtgtttga taacctttgc cttgtgcttt gaaccaagca agtacatcag catctaaccg
    18661 aattgaagtt tgttgcttta ctgggcggta aaattgattt tggcgtacag cattgctcca
    18721 gtctgtaatt tcaggaatat ctgatagatc tagctgatca tcaggaaccg tgcctttagc
    18781 aagcaagcgt tgaatttcag catcttgctt ctcaccaaat ttctcattca gctctttgtg
    18841 tgagtatcta accatgctca tatttgtttc gctccgcttt agtgacttgc cttgcactaa
    18901 tgattcggat gatttcacag tcatcttcat caaaaatggt gtgagccacc aataacatta
    18961 gtacgccttt aactcgtcca atggtttgcc aacgttcttc accattagta tatctgtctt
    19021 ggattgagat ccgtaatgga tcttcaaaaa caaggcttgc agtttcgaaa gagatatcat
    19081 gctttttctg attctttcga ttcttagcct catcccattc aaaatactgt tccataaaaa
    19141 atattcaaat ttgtatatac aataatgtat cacgaaattg tatcactcaa gttgagaagc
    19201 gtaattttta gtcagattta ttggcaaaaa ctatcaaaat cgatcataaa aaagccgact
    19261 tgtttcaaag tcggcttttt gggcattttt ggatttttat atttttatta agtagttgat
    19321 atttaaatta atatacaagt gtacttcgta taatatccat tatgttaaat agtaggggac
    19381 tctaagtaca agattagaaa atttagtctt taagaggaga aatttgttct agcttatctt
    19441 caggattatt ttctctaata tgtataattc gatcataatt ttctactcct cgtaagtgag
    19501 gtggtgcaaa tgctggatac ttgttgaaaa agtgcatttt aatatttagt gcatggtcta
    19561 aaataaaagc acattcaatt ccatagtact tatcattaat aaaaaaattg tctgtagttt
    19621 ctattagttc ttgaatagct aaatccaatt tttgaatttt ttcattaata tctttagttt
    19681 tctcttctat ctttttgtcc attggtatca cctatagaat taagtttccc taaaattaac
    19741 ataatacacc ttatgcgaaa ttccaatgta agcccaaaat agaaatgtcc aacttctcta
    19801 aaatccctgc taaataaact actcttcgcc tttttctaag gcctttttaa tttcaattac
    19861 tgacaataat tctccgccct tttgccaggt atgtaatcct tctaacacct gaataaaaag
    19921 tttatttgct ttaaaatatt cattttcata tgtcttaaca tctttaaaaa ttaaagattt
    19981 acgtacttca ttatgaaact ttgtcgtatt cacaatccga ttggtaatct gttgaggagt
    20041 atcattgcta atatcaatat tgagtttctt aaatgcgaca agaacagcac cacctaattc
    20101 aaatttacgt tgattttcag ctttgcgttt tttcccagca tccttcttct gtagctgact
    20161 caaatacaat tctaaatcac tgtattcaag cttttgcgct ttaaaattca gataccgtgt
    20221 cgccaaggtt tttaaaatat ttagttccat ctgatctagt gcattctttt gaaaaagttc
    20281 atacagatct aaaaacttct gttcatactc ggttttaaga ggcagattat tcaactcttc
    20341 aaacagcaat ttcaacttca gatgttcacg ataaggtttt aaagcctctt tgaccagaac
    20401 ctgatctgtc tgagttagcc cctcaaaatt acaatcaaca ctatttaaag cctttaacac
    20461 ttgagattga agatcagaaa gctgttcttg ctgttctaaa aactctacaa atgcatgtaa
    20521 ctcagcaatc tgtaacaact gagcaggtcg accacgcttt tttgcttttt ccatttccat
    20581 catctgccgc caaattttca gaactgcaac ctctttaaat atggttttac catatttaaa
    20641 gagggcagtc tgaaaataat tatttaatat aaaaataaaa attcttttca agaaatttta
    20701 tttttatatt aaataattcg cacttgacag tttctcctca tcggagaaac tagtacgcaa
    20761 tggggcgctt cccccttgac ccccttcaac cggatttttc agccatacag gcatttcaaa
    20821 tccgggcggt tttcattccg tttcactgca taaaaaccga acccacaacc cagcagaggt
    20881 gaacatggcc agctaccact tcagcgtcaa aagcaaaaat aagggctatg cgaccggcca
    20941 ttatctctac atttcccggc tgatgcagta tgaaggcatc cgcaaaacca gcaatgagac
    21001 catagaacat attgaacctg gtcgatgtat gcctgccttt gtaaaagatc ccattgattt
    21061 ttggcaggca gcagatacgt atgaacgagc caatgccaag gcctacatgg agtatgaaat
    21121 tgccctaccg aatgagttca cgtcagaaca gcgtaaaacg ctcatagaga cgtttttaga
    21181 caaacatata gttccacagc aatatccgca ctcatacgcc atacacaacg taaaatcacg
    21241 tatcagtggc gaagatcagc ctcattgtca tctgatgttc tcgctaaaag cggatgacgg
    21301 cattgaacgc agcgcgcaga acagtacttc aaacgctata accctcaaga tccagccaaa
    21361 ggcggtgcca aaaaaatcca acttcaagat ggccatgaag actattccac ttttttgatc
    21421 tatatccgaa aacaatggga aaatcatttg aatgatgccc ttgcacagca ctgcccgacc
    21481 gtcacctaca cactggatgg ccaagacatc accatcaaaa atcaggtttc agcagacagc
    21541 tatgaaaaat ataacgagat ccacagcacg ctataccttc cagagccaaa actaggcgtt
    21601 ggacaacaaa atgcgacagc ggaatatctc gcccaaatcc aaaaaatcag agaacacaac
    21661 cagcaagaac gagaactcga agaacgccaa aagcaattag atcaacaaca tgaatatttt
    21721 tatagtgctg aaaacaaccc attttcatca ttggaagtca tgtattacct gaattactta
    21781 atcaagaatg caacaaataa ggacaaacta aaaaatgatt tgaatgaaat tatcaaaaac
    21841 caaggcccta tacttaaaca agaagcttgg tccatctacg aaatgaatga aaaactagaa
    21901 gactcaagac gtaacagtac cccatgtttt gagttcgagg tgcattcact tcctgaatac
    21961 gtattaccga tacaaaatac gcctcccaaa cgcactcaat cagaaccagt acaacctaaa
    22021 gctgatgatt atgattacgg tggccctggt ttttaagctc agttggtttt atccaaagtt
    22081 tacagagcga gtgtctacga gcgaacagac acaattaaaa tttttgccat gctttttccc
    22141 tgattacaaa ctcccctttg ctgctgagac tgagatacag agcatcccgg agggtgcgaa
    22201 cagatttaat ttgcatctag gtcgagcgaa gcgagtataa aaaacttatg agcgaagcga
    22261 attccgagtt gcttttgctt ttttgaagtt atcacgagat taacccaaaa attgcccctt
    22321 cgaactgagc gtaagcgaag ttcaatagag tttg
//
