LOCUS       NZ_CP096213            42009 bp    DNA     circular CON 08-JUN-2024
DEFINITION  Enterococcus faecium strain UCH1 plasmid pUCH1-2, complete sequence.
ACCESSION   NZ_CP096213
VERSION     NZ_CP096213.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN27725314
            Assembly: GCF_023204955.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42009)
  AUTHORS   Enroth,T.J., Kirsch,J.M., McCollister,B.D., Johnson,C.N. and
            Duerkop,B.A.
  TITLE     Enterococcus faecium UCH1
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 42009)
  AUTHORS   Enroth,T.J., Kirsch,J.M., McCollister,B.D., Johnson,C.N. and
            Duerkop,B.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-APR-2022) Immunology and Microbiology, University of
            Colorado Anschutz Medical Campus, 12800 East 19th Ave, Aurora, CO
            80045, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: APR-2022
            Assembly Method                   :: Unicycler v. 0.5.0
            Assembly Name                     :: UCH1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 225.8x
            Sequencing Technology             :: Oxford Nanopore; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023204955.1-RS_2024_06_08
            Annotation Date                   :: 06/08/2024 04:36:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,300
            CDSs (total)                      :: 3,209
            Genes (coding)                    :: 3,062
            CDSs (with protein)               :: 3,062
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 51 of 147
            Pseudo Genes (incomplete)         :: 92 of 147
            Pseudo Genes (internal stop)      :: 37 of 147
            Pseudo Genes (multiple problems)  :: 28 of 147
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP096213.1.
            Bacteria and source DNA available from Duerkop Lab, University of
            Colorado Medical School, Aurora, CO.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..42009
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="UCH1"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /plasmid="pUCH1-2"
                     /geo_loc_name="USA"
                     /lat_lon="39.742630 N 104.842026 W"
                     /collection_date="2019"
                     /collected_by="Bruce McCollister"
     gene            1..1041
                     /locus_tag="M0E25_RS15950"
                     /old_locus_tag="M0E25_15950"
     CDS             1..1041
                     /locus_tag="M0E25_RS15950"
                     /old_locus_tag="M0E25_15950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_000997689.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLLK
                     DRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGRVN
                     KRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTTVIA
                     KIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVDIMKE
                     DSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELESYGIDA
                     DKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFNELPTVS
                     TENWLE"
                     /name="replication initiator protein A"
     gene            complement(1657..2337)
                     /locus_tag="M0E25_RS15955"
                     /old_locus_tag="M0E25_15955"
     CDS             complement(1657..2337)
                     /locus_tag="M0E25_RS15955"
                     /old_locus_tag="M0E25_15955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            2483..2566
                     /locus_tag="M0E25_RS15960"
                     /old_locus_tag="M0E25_15960"
     CDS             2483..2566
                     /locus_tag="M0E25_RS15960"
                     /old_locus_tag="M0E25_15960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]; GO:0031556 - transcriptional attenuation by ribosome
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="WP_001814874.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
                     /name="23S rRNA methyltransferase attenuation leader
                     peptide"
     gene            2691..3428
                     /gene="erm(B)"
                     /locus_tag="M0E25_RS15965"
                     /old_locus_tag="M0E25_15965"
     ARG             2692..3425
                     /name="erm(B)"
                     /gene="erm(B)"
                     /gene_name="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE/MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            <3598..3858
                     /locus_tag="M0E25_RS15970"
                     /old_locus_tag="M0E25_15970"
                     /pseudo=""
     CDS             <3598..3858
                     /locus_tag="M0E25_RS15970"
                     /old_locus_tag="M0E25_15970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /GO_component="GO:0005694 - chromosome [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /name="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            4021..>4686
                     /locus_tag="M0E25_RS15975"
                     /old_locus_tag="M0E25_15975"
                     /pseudo=""
     CDS             4021..>4686
                     /locus_tag="M0E25_RS15975"
                     /old_locus_tag="M0E25_15975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
                     /name="IS1182-like element IS1182 family transposase"
     gene            4722..4967
                     /locus_tag="M0E25_RS15980"
                     /old_locus_tag="M0E25_15980"
     CDS             4722..4967
                     /locus_tag="M0E25_RS15980"
                     /old_locus_tag="M0E25_15980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_000567888.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRLL
                     LGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
                     /name="single-stranded DNA-binding protein"
     gene            5070..5939
                     /locus_tag="M0E25_RS15985"
                     /old_locus_tag="M0E25_15985"
     CDS             5070..5939
                     /locus_tag="M0E25_RS15985"
                     /old_locus_tag="M0E25_15985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /protein_id="WP_000228166.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIYY
                     NSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIKRV
                     EQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETYPNA
                     LQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYCINEK
                     KAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINNFLNEE
                     SSDERKQI"
                     /name="nucleotidyltransferase domain-containing protein"
     gene            complement(6028..6708)
                     /locus_tag="M0E25_RS15990"
                     /old_locus_tag="M0E25_15990"
     CDS             complement(6028..6708)
                     /locus_tag="M0E25_RS15990"
                     /old_locus_tag="M0E25_15990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            6725..7201
                     /locus_tag="M0E25_RS15995"
                     /old_locus_tag="M0E25_15995"
     CDS             6725..7201
                     /locus_tag="M0E25_RS15995"
                     /old_locus_tag="M0E25_15995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_029756586.1"
                     /translation="MFFYYSTLFDSRFKTLQQNLQEDDIIYVTDLTRITRSTQDLFELI
                     DNIRDKKASLKSLKDTWLDLSEDNPYSQFLITVMAGVNQLERDLIRMRQREGIELAKKE
                     GKFKGRLKKYHKNHAGMNYAVKLYKEGNMTVNQICEITNVSRASLYRKLSEVNN"
                     /name="recombinase family protein"
     gene            7415..8110
                     /gene="vanR-A"
                     /locus_tag="M0E25_RS16000"
                     /old_locus_tag="M0E25_16000"
     ARG             7416..8107
                     /name="vanR-A"
                     /gene="vanR-A"
                     /gene_name="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="99.57"
                     /coverage="100.0"
     gene            8088..9242
                     /locus_tag="M0E25_RS16005"
                     /old_locus_tag="M0E25_16005"
     CDS             8088..9242
                     /locus_tag="M0E25_RS16005"
                     /old_locus_tag="M0E25_16005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="WP_002305818.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGKL
                     GDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKYFD
                     EINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVMYLA
                     HDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRYNLQT
                     ITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFNNILKN
                     AAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSSDTGGAG
                     LGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
                     /name="vancomycin resistance histidine kinase VanS-A"
     gene            complement(9340..10632)
                     /locus_tag="M0E25_RS16010"
                     /old_locus_tag="M0E25_16010"
     CDS             complement(9340..10632)
                     /locus_tag="M0E25_RS16010"
                     /old_locus_tag="M0E25_16010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1251 family transposase"
                     /protein_id="WP_000122610.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIYT
                     AQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADTSV
                     AKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTPLPK
                     VLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREAVEWI
                     VIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQKHYQLG
                     KQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQLYQDFL
                     YAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPLECLNNHI
                     KVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
                     /name="ISL3-like element IS1251 family transposase"
     gene            10964..11932
                     /locus_tag="M0E25_RS16015"
                     /old_locus_tag="M0E25_16015"
     CDS             10964..11932
                     /locus_tag="M0E25_RS16015"
                     /old_locus_tag="M0E25_16015"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="WP_001059542.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKSA
                     PFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAYSP
                     DSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKAVIE
                     RLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQRMKQ
                     GAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQFLLKL
                     QRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
                     /name="D-lactate dehydrogenase VanH-A"
     ARG             11908..12956
                     /name="vanA"
                     /gene="vanA"
                     /gene_name="glycopeptide resistance gene cluster; Van
                     ligase"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="99.71"
                     /coverage="101.75"
     ARG             11926..12953
                     /name="vanA"
                     /gene="vanA"
                     /gene_name="D-alanine--(R)-lactate ligase VanA"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="99.71"
                     /coverage="100.0"
     gene            12962..13570
                     /locus_tag="M0E25_RS16025"
                     /old_locus_tag="M0E25_16025"
     CDS             12962..13570
                     /locus_tag="M0E25_RS16025"
                     /old_locus_tag="M0E25_16025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="WP_000402348.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTYE
                     LAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRTEM
                     ISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEAQNR
                     RRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
                     /name="D-Ala-D-Ala dipeptidase VanX-A"
     gene            13998..14909
                     /gene="vanY"
                     /locus_tag="M0E25_RS16030"
                     /old_locus_tag="M0E25_16030"
     CDS             13998..14909
                     /gene="vanY"
                     /locus_tag="M0E25_RS16030"
                     /old_locus_tag="M0E25_16030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="WP_000732308.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHLE
                     NSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLLDS
                     NIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGYSEH
                     NSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIRYVGL
                     PHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNLRYEIS
                     GNNIDGVIVTVFPGSTHTNSRR"
                     /name="vanY"
     gene            15062..15547
                     /gene="vanZ-A"
                     /locus_tag="M0E25_RS16035"
                     /old_locus_tag="M0E25_16035"
     ARG             15063..15544
                     /name="vanZ-A"
                     /gene="vanZ-A"
                     /gene_name="glycopeptide resistance protein VanZ-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(15834..16163)
                     /locus_tag="M0E25_RS16040"
                     /old_locus_tag="M0E25_16040"
     CDS             complement(15834..16163)
                     /locus_tag="M0E25_RS16040"
                     /old_locus_tag="M0E25_16040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000754864.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIKI
                     FYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDILS
                     AIRVF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            16468..16797
                     /locus_tag="M0E25_RS16045"
                     /old_locus_tag="M0E25_16045"
     CDS             16468..16797
                     /locus_tag="M0E25_RS16045"
                     /old_locus_tag="M0E25_16045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000629052.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEPK
                     KEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEELA
                     AEIGL"
                     /name="hypothetical protein"
     gene            16787..17074
                     /locus_tag="M0E25_RS16050"
                     /old_locus_tag="M0E25_16050"
     CDS             16787..17074
                     /locus_tag="M0E25_RS16050"
                     /old_locus_tag="M0E25_16050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000312841.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQK
                     TGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(17353..17916)
                     /locus_tag="M0E25_RS16055"
                     /old_locus_tag="M0E25_16055"
     CDS             complement(17353..17916)
                     /locus_tag="M0E25_RS16055"
                     /old_locus_tag="M0E25_16055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000017403.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAVR
                     PQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTPHG
                     RLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQVYS
                     VKEITEMTGISKATLYRYLKDNRE"
                     /name="recombinase family protein"
     gene            18559..19512
                     /locus_tag="M0E25_RS16060"
                     /old_locus_tag="M0E25_16060"
     CDS             18559..19512
                     /locus_tag="M0E25_RS16060"
                     /old_locus_tag="M0E25_16060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="WP_000222572.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNFL
                     KCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEKRSTEGWTPDVIIGRAERTFSCS
                     VSTLYRRFKTGEFNVLHLPMQGKRKPNGYKEKRGKQAFKRNISERKKDYVVFEEEFGHL
                     EGDTIVGIHHKSAVITLVERLSKAIIALKPEGRKAVDIENSINEWLQSVPKNLFKSITF
                     DCGKEFSNWKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRKDGLPKEMEFNQVNQGF
                     ISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA"
                     /name="IS30 family transposase"
     gene            19490..20965
                     /locus_tag="M0E25_RS16065"
                     /old_locus_tag="M0E25_16065"
     CDS             19490..20965
                     /locus_tag="M0E25_RS16065"
                     /old_locus_tag="M0E25_16065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="WP_000443455.1"
                     /translation="MESFVSLNLTNNTSKKNQPKDIKDIVDTRMYKERDDLNYTLIINK
                     DGNYSWRPLVLLHPILYVDLVNCLTKEDHWEELKKRFSEFKKDKNINCYSIPVEASKGS
                     KRTDLGETILNWWEYFEQKSLAQNIKYQYCMFTDIADCYPSIYTHSITWAMYGKEKVKN
                     DENKCSGSLGDKIDKKISGMQHNQTNGIPQGSVLMDFVAEIVLGYVDLRLSKELKKLEN
                     LKDYKVLRYRDDYRIFSNNRNDLEQIMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKK
                     DKLYWEEIKASIRMNATNLDGDREIRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFN
                     KERIIKITSKPNDLLPLIGILVDIMINNPGSLPQCVLIIGQLLNFENESKAREIVEMII
                     NKYALKPNTEFMMIWFQRLTTIFGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKK
                     SFYEGTIKDEEKYIKMSKKIYITEFDDFNDYPF"
                     /name="RNA-directed DNA polymerase"
     gene            21303..>21590
                     /locus_tag="M0E25_RS16070"
                     /old_locus_tag="M0E25_16070"
                     /pseudo=""
     CDS             21303..>21590
                     /locus_tag="M0E25_RS16070"
                     /old_locus_tag="M0E25_16070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
                     /name="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
     gene            complement(21646..22326)
                     /locus_tag="M0E25_RS16075"
                     /old_locus_tag="M0E25_16075"
     CDS             complement(21646..22326)
                     /locus_tag="M0E25_RS16075"
                     /old_locus_tag="M0E25_16075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(<22401..23063)
                     /locus_tag="M0E25_RS16080"
                     /old_locus_tag="M0E25_16080"
                     /pseudo=""
     CDS             complement(<22401..23063)
                     /locus_tag="M0E25_RS16080"
                     /old_locus_tag="M0E25_16080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332718.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /name="replication initiation protein"
     gene            24212..25231
                     /locus_tag="M0E25_RS16085"
                     /old_locus_tag="M0E25_16085"
     CDS             24212..25231
                     /locus_tag="M0E25_RS16085"
                     /old_locus_tag="M0E25_16085"
                     /inference="COORDINATES: protein motif:HMM:NF019371.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="WP_010729551.1"
                     /translation="MKTSNRKYKVKTVNHRIPPKKALCVINNSKVINQELKPYLSEQEM
                     IKKISKDIFLTNSDTILLEKFLKKNSYFRFSIYVKLMKNIDKVTILDVIETYKLDSFIR
                     NQLHYFVNQIEIFWKKSLSDNMCVSYEETSIFPKNQCYLDKNIYSDLKWAEDIIGHFNS
                     FFYSNQSPTFKHHHIKKNHCLPIWALFEEITFGSLTTFINQLNTEYYNNWVMSCYDNPK
                     YKKAIRSWANVIRAYRNKIAHHSRIYAFKVTDAPTIIKNDSKSYFPENNLKETQKLYLY
                     GGLYVIKHLLIYEDSMTQTLWNKFLIDLEKKIDKIPSLEKSNYGFPENWRNKLKIMIV"
                     /name="Abi family protein"
     gene            complement(25733..26149)
                     /locus_tag="M0E25_RS16090"
                     /old_locus_tag="M0E25_16090"
     CDS             complement(25733..26149)
                     /locus_tag="M0E25_RS16090"
                     /old_locus_tag="M0E25_16090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002305824.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSYE
                     PDTNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKIEN
                     QLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
                     /name="hypothetical protein"
     gene            complement(26151..26432)
                     /locus_tag="M0E25_RS16095"
                     /old_locus_tag="M0E25_16095"
     CDS             complement(26151..26432)
                     /locus_tag="M0E25_RS16095"
                     /old_locus_tag="M0E25_16095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000353845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000353845.1"
                     /translation="MDILVRNINPKIITRIDKRCQELTTKTGKKWSRNQYLKILIENDF
                     DHELMNYKKDQFDLLFEKFIAIQAENTNILNDYVHTNNQLIETLIGGI"
                     /name="hypothetical protein"
     gene            complement(26808..27332)
                     /locus_tag="M0E25_RS16100"
                     /old_locus_tag="M0E25_16100"
     CDS             complement(26808..27332)
                     /locus_tag="M0E25_RS16100"
                     /old_locus_tag="M0E25_16100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_002305828.1"
                     /translation="MTEKTIKELAEELGVSKTAINKKVSDENRKLWFSKIGNKFVINET
                     GQKAIKSMFFNENENSNQQLVGEKTKTENHKNANQVPELEVLSLLEQQLNQKDMQLQEK
                     DEQIKQMQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIEKQS
                     KTEKKWWQFWQ"
                     /name="DUF536 domain-containing protein"
     gene            complement(27349..>27663)
                     /locus_tag="M0E25_RS16105"
                     /old_locus_tag="M0E25_16105"
                     /pseudo=""
     CDS             complement(27349..>27663)
                     /locus_tag="M0E25_RS16105"
                     /old_locus_tag="M0E25_16105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332718.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="initiator RepB protein"
                     /name="initiator RepB protein"
     gene            complement(27717..28397)
                     /locus_tag="M0E25_RS16110"
                     /old_locus_tag="M0E25_16110"
     CDS             complement(27717..28397)
                     /locus_tag="M0E25_RS16110"
                     /old_locus_tag="M0E25_16110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            <28473..29180
                     /locus_tag="M0E25_RS16115"
                     /old_locus_tag="M0E25_16115"
                     /pseudo=""
     CDS             <28473..29180
                     /locus_tag="M0E25_RS16115"
                     /old_locus_tag="M0E25_16115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /name="replication initiation protein"
     gene            complement(29317..29733)
                     /locus_tag="M0E25_RS16120"
                     /old_locus_tag="M0E25_16120"
     CDS             complement(29317..29733)
                     /locus_tag="M0E25_RS16120"
                     /old_locus_tag="M0E25_16120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001232859.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSYE
                     PDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKIEA
                     KLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
                     /name="hypothetical protein"
     gene            complement(29736..30020)
                     /locus_tag="M0E25_RS16125"
                     /old_locus_tag="M0E25_16125"
     CDS             complement(29736..30020)
                     /locus_tag="M0E25_RS16125"
                     /old_locus_tag="M0E25_16125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000353844.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESDF
                     DRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
                     /name="hypothetical protein"
     gene            30388..30612
                     /locus_tag="M0E25_RS16130"
                     /old_locus_tag="M0E25_16130"
     CDS             30388..30612
                     /locus_tag="M0E25_RS16130"
                     /old_locus_tag="M0E25_16130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000410576.1"
                     /translation="MEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNMTPERKRSL
                     EKLMQLVNEDGGISDAAFDAWSEFHGEYN"
                     /name="hypothetical protein"
     gene            complement(30915..31010)
                     /locus_tag="M0E25_RS16580"
     CDS             complement(30915..31010)
                     /locus_tag="M0E25_RS16580"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106913803.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(31714..32394)
                     /locus_tag="M0E25_RS16135"
                     /old_locus_tag="M0E25_16135"
     CDS             complement(31714..32394)
                     /locus_tag="M0E25_RS16135"
                     /old_locus_tag="M0E25_16135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            <32470..32634
                     /locus_tag="M0E25_RS16140"
                     /old_locus_tag="M0E25_16140"
                     /pseudo=""
     CDS             <32470..32634
                     /locus_tag="M0E25_RS16140"
                     /old_locus_tag="M0E25_16140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(32681..32917)
                     /locus_tag="M0E25_RS16585"
     CDS             complement(32681..32917)
                     /locus_tag="M0E25_RS16585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_306297428.1"
                     /translation="MKQNTSIAKNTTKFKCTAAAWRISISPTNRTNNRGMILFIWISFF
                     LLGYRVLPAYFAPPKRRGRLERLVRNKNHSLSY"
                     /name="hypothetical protein"
     gene            33015..33194
                     /locus_tag="M0E25_RS16150"
                     /old_locus_tag="M0E25_16150"
     CDS             33015..33194
                     /locus_tag="M0E25_RS16150"
                     /old_locus_tag="M0E25_16150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001120991.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLLI
                     AQEKAGFEVPALKK"
                     /name="hypothetical protein"
     gene            33325..33594
                     /locus_tag="M0E25_RS16155"
                     /old_locus_tag="M0E25_16155"
     CDS             33325..33594
                     /locus_tag="M0E25_RS16155"
                     /old_locus_tag="M0E25_16155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /GO_component="GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="WP_000388479.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKRD
                     YDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
                     /name="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
     gene            33587..33844
                     /locus_tag="M0E25_RS16160"
                     /old_locus_tag="M0E25_16160"
     CDS             33587..33844
                     /locus_tag="M0E25_RS16160"
                     /old_locus_tag="M0E25_16160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /GO_process="GO:0008219 - cell death [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="WP_000588503.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLGK
                     PEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
                     /name="Txe/YoeB family addiction module toxin"
     gene            34482..35306
                     /locus_tag="M0E25_RS16165"
                     /old_locus_tag="M0E25_16165"
     CDS             34482..35306
                     /locus_tag="M0E25_RS16165"
                     /old_locus_tag="M0E25_16165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001809248.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELKT
                     LPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACEIG
                     VKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRNKLV
                     HSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQITLS
                     KELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
                     /name="hypothetical protein"
     gene            complement(35471..36085)
                     /locus_tag="M0E25_RS16170"
                     /old_locus_tag="M0E25_16170"
     CDS             complement(35471..36085)
                     /locus_tag="M0E25_RS16170"
                     /old_locus_tag="M0E25_16170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001261742.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRPV
                     FQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGNPL
                     LDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQRRL
                     VYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
                     /name="recombinase family protein"
     gene            36323..36745
                     /locus_tag="M0E25_RS16175"
                     /old_locus_tag="M0E25_16175"
     CDS             36323..36745
                     /locus_tag="M0E25_RS16175"
                     /old_locus_tag="M0E25_16175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002303116.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELTP
                     LDRDGIAIGNPTNDLTVTENYLIVSPLLALAASKTIRVTGTMIFDKVGWPSRPPQSRNW
                     KEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
                     /name="hypothetical protein"
     gene            36755..36958
                     /locus_tag="M0E25_RS16180"
                     /old_locus_tag="M0E25_16180"
     CDS             36755..36958
                     /locus_tag="M0E25_RS16180"
                     /old_locus_tag="M0E25_16180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002299573.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKSI
                     SNLEDSEEKRKKRDQKTYQKEK"
                     /name="hypothetical protein"
     gene            37169..37753
                     /locus_tag="M0E25_RS16185"
                     /old_locus_tag="M0E25_16185"
     CDS             37169..37753
                     /locus_tag="M0E25_RS16185"
                     /old_locus_tag="M0E25_16185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_094850611.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPGL
                     EMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSSTGQ
                     LMFHLFAAFAEFERNLILERSAAGRASARARGRFGGRPEKLSEQDLELLKTLVDSGTPI
                     KTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
                     /name="recombinase family protein"
     gene            37922..39247
                     /locus_tag="M0E25_RS16190"
                     /old_locus_tag="M0E25_16190"
     CDS             37922..39247
                     /locus_tag="M0E25_RS16190"
                     /old_locus_tag="M0E25_16190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="WP_002303115.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRSD
                     NTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNIFR
                     RYVADEDLLIYSIDESILKVTKSLNLFTTEETRSQRRKKLAQMIQERIKEELGLIATVG
                     VGDNPLLAKLALDNEAKHNEGFIAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRLNQMG
                     ILSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQVLPRD
                     YTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLNIGTSILETRPGFSHQMKIPITDNT
                     KELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQINEENLDKIIDK
                     IRQKYGFTSIVHASSMLESARSITRSTLVGGHAGGNGGIKND"
                     /name="Y-family DNA polymerase"
     gene            39240..39590
                     /locus_tag="M0E25_RS16195"
                     /old_locus_tag="M0E25_16195"
     CDS             39240..39590
                     /locus_tag="M0E25_RS16195"
                     /old_locus_tag="M0E25_16195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000568378.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTEE
                     IAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIRHI
                     EFYQDNKWSRLE"
                     /name="hypothetical protein"
     gene            39587..39766
                     /locus_tag="M0E25_RS16200"
                     /old_locus_tag="M0E25_16200"
     CDS             39587..39766
                     /locus_tag="M0E25_RS16200"
                     /old_locus_tag="M0E25_16200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001021554.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAAA
                     GYHNFRFYIFPLYI"
                     /name="hypothetical protein"
     gene            39902..40192
                     /locus_tag="M0E25_RS16205"
                     /old_locus_tag="M0E25_16205"
     CDS             39902..40192
                     /locus_tag="M0E25_RS16205"
                     /old_locus_tag="M0E25_16205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000026576.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITRQ
                     RRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
                     /name="hypothetical protein"
     gene            40560..41348
                     /locus_tag="M0E25_RS16210"
                     /old_locus_tag="M0E25_16210"
     CDS             40560..41348
                     /locus_tag="M0E25_RS16210"
                     /old_locus_tag="M0E25_16210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /GO_process="GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000101106.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQGN
                     ATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVGSE
                     HRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKLSET
                     IETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRRTITVD
                     EAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
                     /name="AAA family ATPase"
     gene            41335..41661
                     /locus_tag="M0E25_RS16215"
                     /old_locus_tag="M0E25_16215"
     CDS             41335..41661
                     /locus_tag="M0E25_RS16215"
                     /old_locus_tag="M0E25_16215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000796719.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKDQ
                     GSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLAKK
                     QNKI"
                     /name="hypothetical protein"
     ARG             10965..11929
                     /name="vanH-A"
                     /gene="vanH-A"
                     /gene_name="D-lactate dehydrogenase VanH-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             8089..9239
                     /name="vanS-A"
                     /gene="vanS-A"
                     /gene_name="vancomycin resistance histidine kinase VanS-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             13999..14906
                     /name="vanY-A"
                     /gene="vanY-A"
                     /gene_name="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="99.67"
                     /coverage="100.0"
     ARG             12963..13567
                     /name="vanX-A"
                     /gene="vanX-A"
                     /gene_name="D-Ala-D-Ala dipeptidase VanX-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             10965..11932
                     /name="vanH gene in vanA cluster"
                     /gene="vanH gene in vanA cluster"
                     /gene_name="vanH; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             7416..8110
                     /name="vanR gene in vanA cluster"
                     /gene="vanR gene in vanA cluster"
                     /gene_name="glycopeptide resistance gene cluster; vanR"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="99.57"
                     /coverage="100.0"
     ARG             13999..14909
                     /name="vanY gene in vanA cluster"
                     /gene="vanY gene in vanA cluster"
                     /gene_name="vanY; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="99.67"
                     /coverage="100.0"
     ARG             15063..15547
                     /name="vanZ gene in vanA cluster"
                     /gene="vanZ gene in vanA cluster"
                     /gene_name="vanZ; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             8089..9243
                     /name="vanS gene in vanA cluster"
                     /gene="vanS gene in vanA cluster"
                     /gene_name="vanS; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="94.79"
     ARG             12963..13570
                     /name="vanX gene in vanA cluster"
                     /gene="vanX gene in vanA cluster"
                     /gene_name="vanX; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="99.5"
                     /coverage="100.0"
     ARG             2692..3428
                     /name="ErmB"
                     /gene="ErmB"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="98.37"
                     /coverage="98.79"
     Typing          2..1041
                     /name="rep_cluster_889"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(22403..23063)
                     /name="rep_cluster_1093"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.094"
                     /coverage="99.0"
                     /evalue="0.0"
     Typing          complement(27354..27663)
                     /name="rep_cluster_1093"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="84.688"
                     /coverage="99.0"
                     /evalue="1.29e-81"
     Typing          28473..29180
                     /name="rep_cluster_1763"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="98.0"
                     /evalue="0.0"
ORIGIN
        1 atgaatgatt ttaattatta caaatcaaaa gaaatttatc gtgaaaaata ttatcaaatg
       61 cctaaggtat tttttactaa cgaaaaatac atggatctat caaatgatgc aaaaattgct
      121 tatatgctac ttaaagatcg atttgattat tcagtcaaaa ataactgggt agattctgat
      181 gataatatat ttttcatatt cacagttgaa gaattaatga aattgttaca atgccgcgaa
      241 ggtaaagtat ctaaaatcaa aaaggaatta gaaaaagcag gtcttctgaa acagaagaga
      301 ggaagagtaa ataaacgtga cggtaagatt gaatccatgc ctaatttatt gtacttaggc
      361 aagccagaag taacgaatca agacgtcttt aaaatcatgg aagaggaaga caatactgat
      421 accaccgtaa ttgcgaaaat cgcaaatacg gcaaaaccgc gagaaatcaa tgataccacc
      481 gtaattgcga aaatcgcaaa tacggcaaaa tccagtcata tcaaggactc aaccgtaatt
      541 gcgaaaatcg cagacaatct attctattct aattctatag acactaatag acacataata
      601 gacactgaaa ctgatcagtt acaaaatcaa gttttactag ataacttcgt cgacatcatg
      661 aaagaggaca gtataaatac atttgtacca gaaaatgtat taaacttgat aaaaacattt
      721 tctagtactt acgaagacgc tcaaaaaacc gtccaaacta ttcataatgc aaagaaaaaa
      781 gctgaagaat tagagcaaac agttgttgtt tatgaagaac tggaatctta tggaattgat
      841 gctgacaaag gattatatat gactttgctg aaagcttatc aaaaacaaaa aactgaaaaa
      901 gtaaacaatt tgcagaatct aattttcgtt tatgtaaaaa attggtttgt cgaaaaagct
      961 attgcggcaa agcttgcaaa cgaacaaaga gaaacattta acgaattacc aacagttagt
     1021 acggaaaatt ggctagagta gttgataaaa agcgatcact ataaaaatga tcaattttaa
     1081 attagaactt ttttatgatt ttaattttat tacaaatgtt acaaataaat agctattatt
     1141 ccggagtttt tagattaaaa gtttatgaaa acaatcacaa acgtaggttt taaagtcata
     1201 atcgttagat attttagtta tttttcattc aaaaaaatag ggaactagtg tttgcatatg
     1261 tgcttttttg agttataata attcatgaag agaggtaatt cacttatttc cccaagctga
     1321 aaagcctgat attacttctt ttcaggcagt gctgctaata ttcaattaca cttttttgta
     1381 tatttttagt tgttttaaat ttaattgtct gatatgcttg tgatgaattg attttcgttc
     1441 tgcacttttg gacgataaat tgtgataatt gaaaatacaa aaaaaagaaa ggcccctgta
     1501 aggctcggga gactggtaat ctccgtcagt gtcctacagg aaagcattaa gatgacgcct
     1561 taatgcgtgc ccttcagtgt tacggtatta cccgcaacgg acggttctgt tgcaaagttt
     1621 taaataaaga ataaaatccc ttacggtatc tatgatttaa gctgggattc ccaataatac
     1681 cttgatttca gtacagaccg aaaacccgaa gagagtgcct tcttttcggg ttttcttata
     1741 taatcctcga atggcttcca tgcctttaat cgtggtagag gcagtgcgta aacttcgata
     1801 gaatttattg cgtctcttta ctggacgatg gtcttgttca atcaaattat tcaggtattt
     1861 aatggtacga tgttctgtcc cttgataaaa gccgtattct tttagtttct taaaggcact
     1921 tgtaatagag ggggctttat ctgtgactac aaccttcggt tcatcaaact gcttcactaa
     1981 ccgcttaaga aaagcatagg ctgcttgtgt gtcccgtttt ttacgtaacc aaatatccaa
     2041 ggttaaacca tctgcatcga tggctcgata caaataatgc cattttcctt taattttgat
     2101 gtacgtttca tccattttcc atgaataaaa ggatttttta tttttctttt tccaaatttg
     2161 atagagtagt ttgccatatt cttgcaccca acgataaatc gtcgtatgag aaacgttaat
     2221 gccacgatca tataagattt cttgaacttc acgatagcta aggttataac gaagatagta
     2281 gcccacggct acaataatca catcctgctg aaattgcttt cctttaaaat gattcatcgt
     2341 cattcctcct gctatctttt tctattattc taccttattt gatagtagat ttaaaacttt
     2401 gcaacagaac cattttgtgt ataataggaa ttgaagttaa attagatgct aaaaatttgt
     2461 aattaagaag gagggattcg tcatgttggt attccaaatg cgtaatgtag ataaaacatc
     2521 tactgttttg aaacagacta aaaacagtga ttacgcagat aaataaatac gttagattaa
     2581 ttcctaccag tgactaatct tatgactttt taaacagata actaaaatta caaacaaatc
     2641 gtttaacttc tgtatttatt tacagatgta ataacttcag gagtgattac atgaacaaaa
     2701 atataaaata ttctcaaaac tttttaacga gtgaaaaagt actcaaccaa ataataaaac
     2761 aattgaattt aaaagaaacc gataccgttt acgaaattgg aacaggtaaa gggcatttaa
     2821 cgacgaaact ggctaaaata agtaaacagg taacgtctat tgaattagac agtcatctat
     2881 tcaacttatc gtcagaaaaa ttaaaactga acattcgtgt cactttaatt caccaagata
     2941 ttctacagtt tcaattccct aacaaacaga ggtataaaat tgttgggagt attccttacc
     3001 atttaagcac acaaattatt aaaaaagtgg tttttgaaag ccatgcgtct gacatctatc
     3061 tgattgttga agaaggattc tacaagcgta ccttggatat tcaccgaaca ctagggttgc
     3121 tcttgcacac tcaagtctcg attcagcaat tgcttaagct gccagcggaa tgctttcatc
     3181 ctaaaccaaa agtaaacagt gtcttaataa aacttacccg ccataccaca gatgttccag
     3241 ataaatattg gaagctatat acgtactttg tttcaaaatg ggtcaatcga gaatatcgtc
     3301 aactgtttac taaaaatcag tttcatcaag caatgaaaca cgccaaagta aacaatttaa
     3361 gtaccgttac ttatgagcaa gtattgtcta tttttaatag ttatctatta tttaacggga
     3421 ggaaataatt ctatgagtcg cttttttaaa tttggaaagt tacacgttac taaagggaat
     3481 ggagataaat tattagatat actactgaca gcttccaaga agctaaagag gtccctagcg
     3541 cctacgggga atttgtatcg ataaggggta caaattccca ctaagcgctc gggacccctt
     3601 gtaggaaaat gtcctaagtg tggcaacaat attgtattaa aaaaatcgtt ttatggttgt
     3661 tcaaattatc ctgaatgtaa gtttacttta gctgaacatt ttagaaagaa aaaactaacc
     3721 aaaacgaatg taaaagaatt actggaggga aaagaaaccc tggtaaaagg aatcaaaaac
     3781 aaagagaaaa agccctacaa tgccgttgta aaaattgggg aaaagggata tattgatttt
     3841 atctcttttt caaaataaac atggggctga cccaaaagta gctcctatat gaaaaataga
     3901 ggtctttcca tttagatagt agtggaaaga cctctattta tcttttgaaa gtgaatacaa
     3961 aaataaagca cactctgcta taatataggt gattaatcca tttgagagag gtgctttatc
     4021 atgtatcaaa attataccat aaaccaactt tgtttgccta tagatcttga aattaaatta
     4081 gaagaaaatg attttgctca tgccattgtg cagtttgttg actctattcc cgatgaagtc
     4141 tttcttcctt attatcaatc tatgggtaga ccccaatatc atcctcgtat gctactttcc
     4201 attattcttt gtgcctatat tcaaggggtt tattcgggcc gccaaataca aaatatgctg
     4261 atagatagta ttcggatgcg ctacttatct caagagcaat tccctaactt tcgtactatt
     4321 aatcgttttc gcgttcatcc gattatgaac gatattctag atcattcatt tgttcaattt
     4381 cgtgagctac tggttcaaag tggcttaatc agtggcagtg ctctatacat tgatggtaca
     4441 aaaattgaag cggatgcgaa taaatactct ttcgtttgga aaaaaagtat tttaaagtat
     4501 aaggatagcc ttgatcaaaa agcccttgaa aactaccaac aaatggtgga aacaaaaatc
     4561 ttacctgagt taatagatga tttaaaggat gaactttcta tagaagagat tgaaaggatt
     4621 cgtcaatctt tggaagaaaa ggaaaatcaa ttaattgaag cgattgacca aaccgaaaca
     4681 gtagaagggg gctgacccat tattaataag gagtggacaa catgattgat gtaaatgagc
     4741 tattggaaga agctattaga gaaactgaaa atctaaatga tggcgaagtt tttcttgtta
     4801 aagatttatt caagggatat gtggggaata ggatacccag aaaggatcga cttctgcttg
     4861 gaacgttatt tttaaaccat gttagcaaaa tgaatggtaa tttaaaggct attgaaaaga
     4921 cttcatctaa tcagcagagg tataaaaaga caattgataa gttttaacta tcttttgtga
     4981 aattaaaaaa attataaata tgttgagtag aagcaaaaga tttggcttgg aatttttaca
     5041 gcagtgaatc gataaaagga gcatgcttga tggtagataa tattattaaa tcagtagcag
     5101 agaaattatc ctctctgtct tatatagaag gtattgtttt aggtggttca cgtgcaaggg
     5161 gcacccatac agaggattcg gatatagata tcggcatcta ttacaattca gaatcatttg
     5221 acataaatac tattaatcaa ttcgctacaa agctggatga tgagcataga aataaccttg
     5281 ttgtacctcc cggagcatgg ggtgattgga ttaatggcgg cggatggtta gtcataaacg
     5341 ggtatcatgt ggatttaatt ttacgtgata ttaaacgtgt ggaacaaata atgaaagata
     5401 cagagcacgg aattgttact gccaattatc agactgggca tccccatggt tatattagtg
     5461 caatgtatcg aggagaatta gcgattagca aaatactata tgctaagaat gaaagcttat
     5521 gcgaattaaa aaaacaggca gaaacttatc ccaatgcttt gcagaaaagt ttagttaact
     5581 tttttatgtt tgaagcaggg ttctctttaa tgtttgtaaa agcaaattcg ggaacagacg
     5641 ataaatatta tattgcgggt catgtttttc gtatagtttc atgtttaaat caagtgttat
     5701 ttgcatgtaa taatgcttat tgtatcaacg aaaagaaagc tataaaactg cttgaaactt
     5761 ttgaacataa acctgaaaaa tataccgaga aggtaaatca tatttttgaa gtactcggta
     5821 tctcactttt tgaatgctac gacatgaccg agaagcttta taatgaagtg aatgaaattg
     5881 tatcggagat aaataacttt ttaaacgagg agagttcaga tgaaagaaaa caaatatgat
     5941 gataatatat tttttcaaaa atacagtcaa atgggttctg ttgcaaagtt ttaaataaag
     6001 aataaaatcc cttacggtat ctatgattta agctgggatt cccaataata ccttgatttc
     6061 agtacagacc gaaaacccga agagagtgcc ttcttttcgg gttttcttat ataatcctcg
     6121 aatggcttcc atgcctttaa tcgtggtaga ggcagtgcgt aaacttcgat agaatttatt
     6181 gcgtctcttt actggacgat ggtcttgttc aatcaaatta ttcaggtatt taatggtacg
     6241 atgttctgtc ccttgataaa agccgtattc ttttagtttc ttaaaggcac ttgtaataga
     6301 gggggcttta tctgtgacta caaccttcgg ttcatcaaac tgcttcacta accgcttaag
     6361 aaaagcatag gctgcttgtg tgtcccgttt tttacgtaac caaatatcca aggttaaacc
     6421 atctgcatcg atggctcgat acaaataatg ccattttcct ttaattttga tgtacgtttc
     6481 atccattttc catgaataaa aggatttttt atttttcttt ttccaaattt gatagagtag
     6541 tttgccatat tcttgcaccc aacgataaat cgtcgtatga gaaacgttaa tgccacgatc
     6601 atataagatt tcttgaactt cacgatagct aaggttataa cgaagatagt agcccacggc
     6661 tacaataatc acatcctgct gaaattgctt tcctttaaaa tgattcatcg tcattcctcc
     6721 tgctatcttt ttctattatt ctaccttatt tgatagtaga tttaaaactt tgcaacagaa
     6781 cctacaggaa gatgacatca tttatgttac agacttaact cgaatcactc gtagtacaca
     6841 agatctattt gaattaatcg ataacatacg agataaaaag gcaagtttaa aatcactaaa
     6901 agatacatgg cttgatttat cagaagataa tccatacagc caattcttaa ttactgtaat
     6961 ggctggtgtt aaccaattag agcgagatct tattcggatg agacaacgtg aagggattga
     7021 attggctaag aaagaaggaa agtttaaagg tcgattaaag aagtatcata aaaatcacgc
     7081 aggaatgaat tatgcggtaa agctatataa agaaggaaat atgactgtaa atcaaatttg
     7141 tgaaattact aatgtatcta gggcttcatt atacaggaaa ttatcagaag tgaataatta
     7201 gccattctgt attccgctaa tgggcaatat ttttaaagaa gaaaaggaaa ctataaaata
     7261 ttaacagcct cctagcgatg ccgaaaagcc ctttgataaa aaaagaatca tcatcttaag
     7321 aaattcttag tcatttatta tgtaaatgct tataaattcg gccctataat ctgataaatt
     7381 attaagggca aacttatgtg aaagggtgat aactatgagc gataaaatac ttattgtgga
     7441 tgatgaacat gaaattgccg atttggttga attatactta aaaaacgaga attatacggt
     7501 tttcaaatac tataccgcca aagaagcatt ggaatgtata gacaagtctc agattgacct
     7561 tgccatattg gacatcatgc ttcccggcac aagcggcctt actatctgtc aaaaaataag
     7621 ggacaagcac acctatccga ttatcatgct gaccgggaaa gatacagagg tagataaaat
     7681 tacagggtta acaatcggcg cggatgatta tataacgaag ccctttcgcc cactggagtt
     7741 aattgctcgg gtaaaggccc agttgcgccg atacaaaaaa ttcagtggag taaaggagca
     7801 gaacgaaaat gttatcgtcc actccggcct tgtcattaat gttaacaccc atgagtgtta
     7861 tctgaacgag aagcagttat cccttactcc caccgagttt tcaatactgc gaatcctctg
     7921 tgaaaacaag gggaatgtgg ttagctccga gctgctattt catgagatat ggggcgacga
     7981 atatttcagc aagagcaaca acaccatcac cgtgcatatc cggcatttgc gcgaaaaaat
     8041 gaacgacacc attgataatc cgaaatatat aaaaacggta tggggggttg gttataaaat
     8101 tgaaaaataa aaaaaacgac tattccaaac tagaacgaaa actttacatg tatatcgttg
     8161 caattgttgt ggtagcaatt gtattcgtgt tgtatattcg ttcaatgatc cgagggaaac
     8221 ttggggattg gatcttaagt attttggaaa acaaatatga cttaaatcac ctggacgcga
     8281 tgaaattata tcaatattcc atacggaaca atatagatat ctttatttat gtggcgattg
     8341 tcattagtat tcttattcta tgtcgcgtca tgctttcaaa attcgcaaaa tactttgacg
     8401 agataaatac cggcattgat gtacttattc agaacgaaga taaacaaatt gagctttctg
     8461 cggaaatgga tgttatggaa caaaagctca acacattaaa acggactctg gaaaagcgag
     8521 agcaggatgc aaagctggcc gaacaaagaa aaaatgacgt tgttatgtac ttggcgcacg
     8581 atattaaaac gccccttaca tccattatcg gttatttgag cctgcttgac gaggctccag
     8641 acatgccggt agatcaaaag gcaaagtatg tgcatatcac gttggacaaa gcgtatcgac
     8701 tcgaacagct aatcgacgag ttttttgaga ttacacggta taacctacaa acgataacgc
     8761 taacaaaaac gcacatagac ctatactata tgctggtgca gatgaccgat gaattttatc
     8821 ctcagctttc cgcacatgga aaacaggcgg ttattcacgc ccccgaggat ctgaccgtgt
     8881 ccggcgaccc tgataaactc gcgagagtct ttaacaacat tttgaaaaac gccgctgcat
     8941 acagtgagga taacagcatc attgacatta ccgcgggcct ctccggggat gtggtgtcaa
     9001 tcgaattcaa gaacactgga agcatcccaa aagataagct agctgccata tttgaaaagt
     9061 tctataggct ggacaatgct cgttcttccg atacgggtgg cgcgggactt ggattggcga
     9121 ttgcaaaaga aattattgtt cagcatggag ggcagattta cgcggaaagc aatgataact
     9181 atacgacgtt tagggtagag cttccagcga tgccagactt ggttgataaa aggaggtcct
     9241 aagagatgta tataattttg gctctttgtc aaatgatgtt ggtaaagaga aatcttagaa
     9301 taattggaga tcaagtggat cagttcctct tgatcttttt tagttgaaaa tcaatgcgtt
     9361 gccatgacga atcatgatgc gcaatttgaa attataaaag ctacgaaagc catatgcatt
     9421 tcgttttaac actttgatat ggttgttcag acattcaagt gggccatttg aataactttg
     9481 ttgtaaagca tttttgattt gtggcagaaa tttctggaac gttctcaagg tcgtctgata
     9541 gccttcggga agcatgatat tattggtaag tagttcttca aacgatacgt agtctcgttc
     9601 ctttacagcg taaagaaagt cttgatataa ctgatagcct acacgcaaag cagggctccc
     9661 tttcagtaag cgatccacaa tatcggtctc tgttaaatga gctttgaagc caggtcgcca
     9721 aaggcgtcga gtataatcaa gcttgcgttc atctttttga agaagtttcc agtatctttt
     9781 taattgctta cctaattgat agtgtttttg ttctttgctt tttaatagtt ggttcgtttc
     9841 tttgattcga tgattgcgaa aggtacgacc aatatgttgg acgatgtgaa accggtcaat
     9901 aatcagctgt gcttttggaa acagcttttt aacgagcgat acataaggag cgtacatatc
     9961 aatcacgatc cattcgaccg cttcacgaat ttctcgtgaa aaatgactaa aataacgttt
    10021 taaaaaaggc agttgtcggt tctcgacaat gtccaataag cgctgtgttt gtccatccat
    10081 catgatgaaa ctcatagcac ctgaaacacc ccgaactgat ttgaattcat caaaacaaag
    10141 taccttaggt aacggtgtcc gaaaaggatt caacggacga taaaatcgct tcataatacg
    10201 gtaaacagaa gagaccgata gatttttctg agcggcgatc tctgtcattg aggtattttt
    10261 tttcagacga gtcacgacag accagcggac tttctcactg atgaaacaat gttttttcgc
    10321 aacagaagta tctgcgacaa aggtccgctg acaagctttg catttgaagc gttgcttttt
    10381 caattcgagg taggtacggt attcagaaac atcgttcatt aacaaccgga cggttgttgt
    10441 accccaacgc acaatatctg aagcaatctg gtgtttacag tggatgcatt cttgggctgt
    10501 ataaatcaag tttccacgat aaatatgaca gatttgccct ttgtattttt cttttgtgag
    10561 acaattttcg ttaaaagtaa ctgataagtc tagaatatct aatgtttctt tgataaggtg
    10621 agtgtaagac atcttgattc ctccttttgg gttggttcgc caaattaatt ctaaaggatt
    10681 tcaaggtgtc ttttctatat gttttggaaa ataaaaaaga tgctggtgtc atccaccaac
    10741 atcaaaaagt atagagccat aattttttag gaaaatctca aggttatctt tactttttct
    10801 taggaaatta acaatttaat attaagaaac ggctcgttct tacacggtag acttaatacc
    10861 gtaagaacga gccgttttcg ttcttcagag aaagatttga caagattacc attggcatcc
    10921 ccgttttatt tggtgccttt cacagaaagg gttggtctta attatgaata acatcggcat
    10981 tactgtttat ggatgtgagc aggatgaggc agatgcattc catgctcttt cgcctcgctt
    11041 tggcgttatg gcaacgataa ttaacgccaa cgtgtcggaa tccaacgcca aatccgcgcc
    11101 tttcaatcaa tgtatcagtg tgggacataa atcagagatt tccgcctcta ttcttcttgc
    11161 gctgaagaga gccggtgtga aatatatttc tacccgaagc atcggctgca atcatataga
    11221 tacaactgct gctaagagaa tgggcatcac tgtcgacaat gtggcgtact cgccggatag
    11281 cgttgccgat tatactatga tgctaattct tatggcagta cgcaacgtaa aatcgattgt
    11341 gcgctctgtg gaaaaacatg atttcaggtt ggacagcgac cgtggcaagg tactcagcga
    11401 catgacagtt ggtgtggtgg gaacgggcca gataggcaaa gcggttattg agcggctgcg
    11461 aggatttgga tgtaaagtgt tggcttatag tcgcagccga agtatagagg taaactatgt
    11521 accgtttgat gagttgctgc aaaatagcga tatcgttacg cttcatgtgc cgctcaatac
    11581 ggatacgcac tatattatca gccacgaaca aatacagaga atgaagcaag gagcatttct
    11641 tatcaatact gggcgcggtc cacttgtaga tacctatgag ttggttaaag cattagaaaa
    11701 cgggaaactg ggcggtgccg cattggatgt attggaagga gaggaagagt ttttctactc
    11761 tgattgcacc caaaaaccaa ttgataatca atttttactt aaacttcaaa gaatgcctaa
    11821 cgtgataatc acaccgcata cggcctatta taccgagcaa gcgttgcgtg ataccgttga
    11881 aaaaaccatt aaaaactgtt tggattttga aaggagacag gagcatgaat agaataaaag
    11941 ttgcaatact gtttgggggt tgctcagagg agcatgacgt atcggtaaaa tctgcaatag
    12001 agatagccgc taacattaat aaagaaaaat acgagccgtt atacattgga attacgaaat
    12061 ctggtgtatg gaaaatgtgc gaaaaacctt gcgcggaatg ggaaaacgac aattgctatt
    12121 cagctgtact ctcgccggat aaaaaaatgc acggattact tgttaaaaag aaccatgaat
    12181 atgaaatcaa ccatgttgat gtagcatttt cagctttgca tggcaagtca ggtgaagatg
    12241 gatccataca aggtctgttt gaattgtccg gtatcccttt tgtaggctgc gatattcaaa
    12301 gctcagcaat ttgtatggac aaatcgttga catacatcgt tgcgaaaaat gctgggatag
    12361 ctactcccgc cttttgggtt attaataaag atgataggcc ggtggcagct acgtttacct
    12421 atcctgtttt tgttaagccg gcgcgttcag gctcatcctt cggtgtgaaa aaagtcaata
    12481 gcgcggacga attggactac gcaattgaat cggcaagaca atatgacagc aaaatcttaa
    12541 ttgagcaggc tgtttcgggc tgtgaggtcg gttgtgcggt attgggaaac agtgccgcgt
    12601 tagctgttgg cgaggtggac caaatcaggc tgcagtacgg aatctttcgt attcatcagg
    12661 aagtcgagcc ggaaaaaggc tctgaaaacg cagttataac cgttcccgca gacctttcag
    12721 cagaggagcg aggacggata caggaaacgg caaaaaaaat atataaagcg ctcggctgta
    12781 gaggtctagc ccgtgtggat atgtttttac aagataacgg ccgcattgta ctgaacgaag
    12841 tcaatactct gcccggtttc acgtcataca gtcgttatcc ccgtatgatg gccgctgcag
    12901 gtattgcact tcccgaactg attgaccgct tgatcgtatt agcgttaaag gggtgataag
    12961 catggaaata ggatttactt ttttagatga aatagtacac ggtgttcgtt gggacgctaa
    13021 atatgccact tgggataatt tcaccggaaa accggttgac ggttatgaag taaatcgcat
    13081 tgtagggaca tacgagttgg ctgaatcgct tttgaaggca aaagaactgg ctgctaccca
    13141 agggtacgga ttgcttctat gggacggtta ccgtcctaat cgtgctgtaa actgttttat
    13201 gcaatgggct gcacagccgg aaaataacct gacaaaggaa agttattatc ccaatattga
    13261 ccgaactgag atgatttcaa aaggatacgt ggcttcaaaa tcaagccata gccgcggcag
    13321 tgccattgat cttacgcttt atcgattaga cacgggtgag cttgtaccaa tggggagccg
    13381 atttgatttt atggatgaac gctctcatca tgcggcaaat ggaatatcat gcaatgaagc
    13441 gcaaaatcgc agacgtttgc gctccatcat ggaaaacagt gggtttgaag catatagcct
    13501 cgaatggtgg cactatgtat taagagacga accatacccc aatagctatt ttgatttccc
    13561 cgttaaataa acttttaacc gttgcacgga caaactatat aagctaactc tttcggcagg
    13621 aaacccgacg tatgtaactg gttcttaggg aatttatata tagtagatag tattgaagat
    13681 gtaaggcaga gcgatattgc ggtcattatc tgcgtgcgct gcggcaagat agcctgataa
    13741 taagactgat cgcatagagg ggtggtattt cacaccgccc attgtcaaca ggcagttcag
    13801 cctcgttaaa ttcagcatgg gtatcactta tgaaaattca tctacattgg tgataatagt
    13861 aaatccagta gggcgaaata attgactgta atttacgggg caaaacggca caatctcaaa
    13921 cgagattgtg ccgtttaagg ggaagattct agaaatattt catacttcca actatatagt
    13981 taaggaggag actgaaaatg aagaagttgt tttttttatt gttattgtta ttcttaatat
    14041 acttaggtta tgactacgtt aatgaagcac tgttttctca ggaaaaagtc gaatttcaaa
    14101 attatgatca aaatcccaaa gaacatttag aaaatagtgg gacttctgaa aatacccaag
    14161 agaaaacaat tacagaagaa caggtttatc aaggaaatct gctattaatc aatagtaaat
    14221 atcctgttcg ccaagaaagt gtgaagtcag atatcgtgaa tttatctaaa catgacgaat
    14281 taataaatgg atacgggttg cttgatagta atatttatat gtcaaaagaa atagcacaaa
    14341 aattttcaga gatggtcaat gatgctgtaa agggtggcgt tagtcatttt attattaata
    14401 gtggctatcg agactttgat gagcaaagtg tgctttacca agaaatgggg gctgagtatg
    14461 ccttaccagc aggttatagt gagcataatt caggtttatc actagatgta ggatcaagct
    14521 tgacgaaaat ggaacgagcc cctgaaggaa agtggataga agaaaatgct tggaaatacg
    14581 ggttcatttt acgttatcca gaggacaaaa cagagttaac aggaattcaa tatgaactat
    14641 ggcatattcg ctatgttggt ttaccacata gtgcgattat gaaagaaaag aatttcgttc
    14701 tcgaggaata tatggattac ctaaaagaag aaaaaaccat ttctgttagt gtaaatgggg
    14761 aaaaatatga gatcttttat tatcctgtta ctaaaaatac caccattcat gtgccgacta
    14821 atcttcgtta tgagatatca ggaaacaata tagacggtgt aattgtgaca gtgtttcccg
    14881 gatcaacaca tactaattca aggaggtaag gatggcggaa tgaaaccaac gaaattaatg
    14941 aacagcatta ttgtactagc acttttgggg taacgttagc tttttaattt aaaacccacg
    15001 ttaactagga cattgctata ctaatgatac aacttaaaca aaagaattag aggaaattat
    15061 attgggaaaa atattatcta gaggattgct agctttatat ttagtgacac taatctggtt
    15121 agtgttattc aaattacaat acaatatttt atcagtattt aattatcatc aaagaagtct
    15181 taacttgact ccatttactg ctactgggaa tttcagagag atgatagata atgttataat
    15241 ctttattcca tttggcttgc ttttgaatgt caattttaaa gaaatcggat ttttacctaa
    15301 gtttgctttt gtactggttt taagtcttac ttttgaaata attcaattta tcttcgctat
    15361 tggagcgaca gacataacag atgtaattac aaatactgtt ggaggctttc ttggactgaa
    15421 attatatggt ttaagcaata agcatatgaa tcaaaaaaaa ttagacagag ttattatttt
    15481 tgtaggtata cttttgctcg tattattgct cgtttaccgt acccatttaa gaataaatta
    15541 cgtgtaagat gtctaaatca agcaatctga tctttcatac acataaagat attgaatgaa
    15601 ttggattaga tggaaaacgg gatgtgggga aactcgcccg taggtgtgaa gtgaggggaa
    15661 aaccggtgat aaagtaaaaa gcttacctaa cactatagta acaaagaaag cccaattatc
    15721 aattttagtg ctgaggaatt ggtctcttta ataaatttcc ttaacgttgt aaatccgcat
    15781 tttcctgacg gtacccccaa actaagattt catagataga ttttctgata actttaaaaa
    15841 acacgaatag cggaaaggat gtcttcattc gctaaagagt aataaactac ttttccatct
    15901 tgacgtgatt ttgccattcc atgttttttt aaaaaacgta aatggtgtga cgttgtagcg
    15961 acactagcag taagtatttc tgctaaatca cagacgcaca tttccttata ggtttctaaa
    16021 gcatagaaaa ttttaattct agaaaaatcg ctgaaacatt tccctaacac aagtaagttt
    16081 gaaaaatctt tttgatccaa tttatttttt attccattta ctttttcttt atgtacgaca
    16141 gtcacttggc aaactttttt cattcatctc acctcacatt caaacgatta tttgaatgaa
    16201 gtatacctat ttgatcactc ttttgtcaat ctaccttaat tccaatacac tattataagc
    16261 aatttcatgt attgaagtaa acttacttgc aagtgcgttt ttgattccaa gttaaaaaca
    16321 tattattatt ctacataatt tcctaatcaa ataaaactcc tttgaaaatt gttctaaagg
    16381 agttttatta ttttgtattt ctactaaaaa tagcgtacaa tgtaattact aagtaattac
    16441 gaaatgtaaa ataatggagg aaataatatg attacaaaaa caagaaaaca aggaaattct
    16501 attatgttaa cggtccctaa agaattcgat gtgcccaatg gtgttgaagt agaagctaag
    16561 cttgtagaga atggtatcct ttatgagttt gtagagccta aaaaagaatt ttttgatttt
    16621 agtgaagata ttttggctga tattctttca gaaggttata gcaaacaaga gatcttaaaa
    16681 gaatttagaa atagaaaaaa tgcgttaact tctgcattta aatctattgc tgaagatact
    16741 gttgcaaatt ctaaaccgat gacaaaagag gagttggcag cagaaattgg cttatgagat
    16801 tctaccttct aaacacgtaa taaagtatct aaaaaaatta aaagagaaaa cattaaaaga
    16861 acaattttta acgataattt atgatgagat agcagttcgt cctcattcgg gagaacaaaa
    16921 aacgggtgat ttatcaggaa tttgggctat tggattcaag tatgcaggta cgacatatcg
    16981 cgttgcatat gaaattaaag ataatgcagt gatacctatc ttactatgtg gaacgcatga
    17041 aaatttttat gaacaattaa aaaagattag gtaagaaccc aatgtttcaa cttgagagga
    17101 tagacgacac tttaaaagat aatttttaac agctgagagt tgtaataccc tataatttta
    17161 aaccactaac ctatatattt atgaaaaata gaaaaaatta aaacgcattt taagcctctt
    17221 tcaaattaaa agcttcatcc ttatgcacaa agagggctta aaatgcgtta ttttatattg
    17281 ttttttagta ataataaaaa aatcactcta attctcccat aaatattata gattcctaaa
    17341 gattaaaata gattattccc tattgtcttt taagtagcgg tagagtgttg ccttgctaat
    17401 accagtcatt tccgtaattt cttttacgct ataaacctga cttttataca attttactgc
    17461 tcgatcaaca tctttctggt tcactcgtgg acggccacct ttacgacctc tcgcacgtgc
    17521 acttttcaaa ccttctttgg tacgttcaac aattaaatca cgttcgaact gactaaatgc
    17581 ttggaagaca gtcatcatta agcgtccgtg aggcgtgctg gtatcgaagt tttctttcaa
    17641 gctcaccagc ttaacatggt gttcttcaaa ataggtaaca aggtcaatca aatcctttgt
    17701 actacgaccc aatcgagaaa aactttctac aattaccgta tctcccggac gaattttatc
    17761 ttttaaacga tttagttggg gacgaaccgc tttggttccc gtcattttct cagttaggat
    17821 ttcattacaa ttttgttcat tgagtaagtc taattgacga tttagttctt gtgaacgtgt
    17881 actcactcgg gcataaccat aaatgtatcc actcatgctt ttcttccttt cgtactttaa
    17941 ttctggcttg attgtatcat aaaagggagt tatagataca tagttaatgc aacaagttat
    18001 gatacaaaat atgacctctt ttatttaata aaagaggtca tttcattttg tctcataatc
    18061 gattgttttt gatacgagtg tgtatacgaa ataaacaaaa aaatcttaag taaatttcta
    18121 gatacctaat ttaatcctaa ctagtgtatc ctaaagttaa taacgagttt atcacaatga
    18181 aaattataaa atgctcccat attagatata acatgcaata tttgaattag aactacaaaa
    18241 tttattcgtt ttataaagta aataatgttg agatactaag gaatagaata ttataaggaa
    18301 ttgagctgaa tgtattggat aaaaaaagaa taactttatt agagatggac tataaaaatg
    18361 ctcgtaattt tcttctgaag tctgaaagct atttgaatgc tcagctacca gaatatatta
    18421 gttttgacga aactttaaaa tctgctaaaa aagttttaac ttcgccgttt gtataattaa
    18481 gcgagacaaa taaaaaagcc atttatgtta cactcaaatt gtaatacccg ctaaagcata
    18541 caaggagagt gaacataaat gacttatacc catcttacac caaacgagct tgtaatgata
    18601 gaagcatatt ttcatcaaga aactccggtt gctatcgttg cgaagcagct taaacgtgga
    18661 cgccaaacaa tttacaatgt ctataacttt ctcaaatgtg gtggaacagc acttgaatac
    18721 tttgaacaat acaaagaaaa taagcgacgt tgtgggagaa ccgaaatcat ttttcctgct
    18781 gaggaaaaag aatacattga aaaaagatca actgaaggtt ggaccccaga cgtcattatt
    18841 ggccgtgcag agcgaacctt ctcttgttca gtaagtaccc tctatcgccg gtttaagacg
    18901 ggagaattca atgttttaca tttaccgatg caaggaaaac gaaaaccaaa tggttataag
    18961 gaaaaacgtg gaaaacaggc attcaaaaga aatatttctg aacgtaaaaa agattatgtc
    19021 gttttcgaag aagagtttgg acatttagag ggtgatacga ttgtcggcat ccaccataaa
    19081 agtgccgtca tcacactcgt tgagcgactt tcaaaagcca ttatcgcctt gaaaccagaa
    19141 ggccgtaagg cagttgatat tgaaaattcg attaatgaat ggcttcaatc cgtacccaaa
    19201 aatcttttca aatcaattac ctttgattgt ggaaaagaat tctctaattg gaaaagtatt
    19261 agtaatacga atgatattga tatttatttc gcagacccag gaacgccttc ccaacgggga
    19321 ttaaatgaac attcaaacgg actcctccga aaagatggac taccaaaaga aatggaattc
    19381 aaccaagtca atcaaggatt catctcatcc gttgcgtcca aaagaaacca tatccctaga
    19441 aaatcactaa attaccaaac accattagaa gtttttttga gttacgtaaa tggaaagttt
    19501 tgtctcgctt aatttgacaa ataatacttc aaaaaaaaac caaccgaaag atataaaaga
    19561 tattgtagat acacgaatgt ataaagaacg tgatgactta aactatacgc ttattatcaa
    19621 taaagatgga aactattcat ggcgtcctct cgttctacta catcctattc tatatgtaga
    19681 tttggttaat tgtctcacta aagaagacca ttgggaggag ttaaaaaaga ggtttagtga
    19741 atttaaaaaa gataaaaata ttaactgtta ttctatacct gttgaagctt ccaaaggttc
    19801 aaaaaggaca gatcttggtg aaacaatact aaactggtgg gaatattttg aacaaaaaag
    19861 cttagctcag aatattaaat accaatattg catgtttact gacatcgctg attgttatcc
    19921 atcaatttat actcactcta taacatgggc catgtatggt aaagaaaaag ttaaaaatga
    19981 tgaaaataag tgttcgggct cacttggcga taaaatagat aaaaaaatat ctggaatgca
    20041 acacaatcaa acaaatggta tccctcaggg ttccgttctt atggattttg tagcagagat
    20101 cgttctaggg tatgttgatt tgagattatc gaaagaatta aaaaaattag aaaatttaaa
    20161 agattacaaa gtactcagat atagagatga ttatagaata ttttcaaata atcgtaatga
    20221 tttggaacaa attatgaaag tgttatcaga agtcttatat gatttaaatt ttaagttaaa
    20281 ttctagtaaa acaaaattat cagatgatat tatcatagat tctatcaaaa aagataagct
    20341 ctattgggaa gaaattaagg caagtataag aatgaatgcc acaaacttag atggtgatag
    20401 agaaattcgt tatagtataa atttacaaaa acatttattg gaaataaaaa agttagcaga
    20461 taagcatcct aattcaggcc aattgaaaaa agcactttct gagtttaata aagaacgcat
    20521 tattaaaatc acttcaaagc cgaacgatct tttaccactt attggtatcc tggtagatat
    20581 catgataaat aacccgggtt ctttgccgca gtgtgtctta attatagggc agttattaaa
    20641 tttcgaaaat gagagtaagg ctagagaaat agttgaaatg attataaaca aatatgcttt
    20701 aaagccaaat actgaattta tgatgatatg gtttcaaaga ttgaccacca tttttggaga
    20761 aatgtttgat agtgttttat catccgaatt tgtatctaaa atcaaagatc ctgtctctaa
    20821 tcagatgttt tctgtagact ggctaaatga agatgctaag aaatcttttt atgaagggac
    20881 cattaaagac gaagagaaat atattaaaat gagtaagaaa atatatatta ctgaatttga
    20941 tgattttaat gattatcctt tttaagtgaa aatttagaat gaatataaaa aacattacaa
    21001 tctaattttt ttaaaaaaat gttatatcgg aagtaatctc ttgatttcta tactataaga
    21061 taagaaaacc actatttaac aaggttattc gaaccttatt ttaagttact tattatttaa
    21121 tgtatcgaaa aaggtgaaat aggtttgtta taataagaat taagtaagac atgaattgtc
    21181 taagcaaatg tagcttatcc atttcattaa aatacatatg gtgaaaaaac aagttcaaat
    21241 agtaactaat tttttaaaaa actgatttat aaaaaataca acacgaatga ggaaaataac
    21301 caatgacaga acaaatcgaa aaaaattcaa aaagcttata tcaggcactg tggaattccg
    21361 cagatatcct gcgttcaaaa atggacgcta atgaatacaa gagctattta ctaggcttgg
    21421 tcttttataa atacttatcc gacaacatgc tgcggtatgt ctccgttcta ttggaggaag
    21481 aaacggacga cctaaataaa gcacaagacc tttacgttga agcatttaaa gatgcagata
    21541 taaaggatga tctcttgtat gaactaaaag atgagttttc atataccatc gggttctgtt
    21601 gcaaagtttt aaataaagaa taaaatccct tacggtatct atgatttaag ctgggattcc
    21661 caataatacc ttgatttcag tacagaccga aaacccgaag agagtgcctt cttttcgggt
    21721 tttcttatat aatcctcgaa tggcttccat gcctttaatc gtggtagagg cagtgcgtaa
    21781 acttcgatag aatttattgc gtctctttac tggacgatgg tcttgttcaa tcaaattatt
    21841 caggtattta atggtacgat gttctgtccc ttgataaaag ccgtattctt ttagtttctt
    21901 aaaggcactt gtaatagagg gggctttatc tgtgactaca accttcggtt catcaaactg
    21961 cttcactaac cgcttaagaa aagcataggc tgcttgtgtg tcccgttttt tacgtaacca
    22021 aatatccaag gttaaaccat ctgcatcgat ggctcgatac aaataatgcc attttccttt
    22081 aattttgatg tacgtttcat ccattttcca tgaataaaag gattttttat ttttcttttt
    22141 ccaaatttga tagagtagtt tgccatattc ttgcacccaa cgataaatcg tcgtatgaga
    22201 aacgttaatg ccacgatcat ataagatttc ttgaacttca cgatagctaa ggttataacg
    22261 aagatagtag cccacggcta caataatcac atcctgctga aattgctttc ctttaaaatg
    22321 attcatcgtc attcctcctg ctatcttttt ctattattct accttatttg atagtagatt
    22381 taaaactttg caacagaacc tgtaaattga tagccaatga caggctttcc ccgtcctttt
    22441 ccgtatctct tttggattgt cagacctttg aagattgcgg ttagttcttg gcgaataggc
    22501 tttataattt ttttatttat atcactttct ctataacttt tagggatatc aagtaattca
    22561 tgaaagtctt cttttgaaaa ataggcaatt cctttggttc tgtattgttt taataatcta
    22621 aacatggttt tggaataact gctttctaat tcattgaatt gttggagaga atatcgaacc
    22681 cattcttcaa gattattaag taagggtaag gctttctcat ggacttgtat ttcagcaaaa
    22741 ggaatatcag cttttccatc gattttaaat tgattaaata aaacaaatcg ttcacgttgc
    22801 aaaccgtcag cacttcttct accaaaacgt aaatccatta atttgtcata cgttgtttct
    22861 aaatcatcta tgaatcgaac atttgcagtt gctttataat tgcttaaatc ttttaattgt
    22921 tcgaatgtaa attgtacttt tttatcgcct acgtcacgca ttctagatac tatagagaag
    22981 aataaattca tttctactga cgtaaatttg cgtaaaggaa tcgtatttaa ttcatggtgg
    23041 tatttcacaa tttcatttgc cataaaatcc tccttcaaga ttaactactt aacaaaatta
    23101 taaagagctt tctaataggg gtcaagcccc taattaaaga cccctaaaaa cagacaaaaa
    23161 gacccccaaa aacagacaaa aagaccccta aaaacagaca aaaagacccc taaaaacaga
    23221 caaaaagacc cccaaaagat tctgcacacc ttgggagagt aagcatacag ccgacggtaa
    23281 agaggtttaa aaagaggttt aaaaagagat tataaaagag gagaggggca aaatttcccg
    23341 cctaaaaatt ttctgctttt ttagccaaac aggttcgcga attttactaa actgggaaac
    23401 ttgctccctc tggtcgctaa aaaggtgtga gggaaaaaca ccctcacatt gtacctgcgc
    23461 agtcgcctaa aggctccttt gctaaaaacg ttgtttaaag agattttttt agaggctctg
    23521 cgcgctcgtt taagccgttt taagacagtt tagtatggat aacccttatc ttgttcttaa
    23581 agcaccttac aggcggtcag ggcaagccct aacaaccctt aaagagcata aaaccatcct
    23641 aaaattcgat ttaatctgtc ttatctatgt tcttgtatat tttatatacc ttgggtagta
    23701 aaacgtctga aaacgcaaat aagagcgtat gaaacaaaac aataagcaac cgattcagca
    23761 gaattccgga ggagccattt tcgtacgtta gcaaaaaagt gctgttgcta aaagctgctt
    23821 gcggtgcgga gcgaacaagg tctcctagag cgagacgtgt acaaacaagc ttacaaattc
    23881 gtgaaaggca ccggttttgc gccatttcca agcaaaaaaa ggtctatcga gcttgctcga
    23941 tagaccgatc gcatttagcc ccccgcattc taacaggggg ggaataatgt gaaaaattat
    24001 ggtagtaatg cttgatatat aggcatttct tttggttgca cacttaaaaa aaatcacgat
    24061 tttgacaact aaatttttaa ataaaaaagc tttacagttt aattcaaatg tgttttaata
    24121 tatctatcag tacttgccac gcctctgatt taatatcatg cgcattatgg tagggctttt
    24181 tttttatatt tttttaagaa agaagattct tatgaagaca tcaaatagaa aatataaagt
    24241 taaaacagtt aatcatagaa ttccacctaa aaaggcatta tgtgtaatta ataattccaa
    24301 agtaattaat caagagttaa aaccatattt atccgagcaa gaaatgataa aaaaaataag
    24361 taaagatatt tttttaacaa attccgatac aattttatta gaaaagtttt taaagaaaaa
    24421 tagttatttt cgatttagta tttatgttaa attaatgaaa aatatagata aagttactat
    24481 tctagatgtt attgaaacgt acaaattaga ttcattcatt cgtaatcaat tgcattattt
    24541 tgtgaatcaa atagaaattt tttggaaaaa atctctttca gataatatgt gcgtttctta
    24601 tgaagaaact agcatatttc cgaagaatca gtgttatttg gataaaaata tttattcaga
    24661 tttgaaatgg gctgaagata taattggtca ttttaatagt tttttttatt caaatcaaag
    24721 tcccactttt aaacatcatc atataaaaaa aaatcattgt ttaccaatat gggctttatt
    24781 tgaagaaata acatttggta gtttaacaac atttattaat caacttaata cagagtatta
    24841 taataattgg gtcatgagct gttatgataa tcctaaatac aaaaaagcta tacgaagttg
    24901 ggcaaacgta attagagctt atagaaataa gatagctcat cattcaagaa tatatgcatt
    24961 taaagttact gacgctccaa caatcataaa aaatgattcc aaaagttatt ttcctgaaaa
    25021 taacttaaaa gaaacccaaa agttatattt gtatggagga ttatacgtta taaaacatct
    25081 gttaatatat gaagatagca tgacacaaac tttatggaat aaatttctaa tagatttaga
    25141 aaaaaagatc gataaaatcc cttccttaga aaaatccaat tatggttttc cggaaaattg
    25201 gagaaacaag ttaaaaataa tgattgttta attgttattt aaattgttag tagacataat
    25261 gtgtatacta ccaagtagcc cctggatcaa ccgatccagg ggaagacttt gtgattttca
    25321 attggtctat ctaaaacatc tttttaaaag cttgattctt cgctgttggc ttttttcgat
    25381 tctttgtgaa tattcagtga ttattttttt actacttgtt attttccgag ggatttgtta
    25441 aaagtttaat agcgtttctc agtaagggac gtcgtttttt cattttccta tgtatggact
    25501 gctcgaacga gcagcctttt tttattccag ggaacgtcct attctttgag tttccatgct
    25561 attgaataac cgggacttag ggattagggc agcgccccaa aatgaaaaaa gaaaaatccg
    25621 cttctgcgaa ttcttctttt ttttcgcaag ttggtaccaa cttgcaaatc ttgctggaag
    25681 accgatccct aaaaagaaat cgaggaattt ttttgttttt cggtttcttt ttttatcttt
    25741 ttagaaagtt tgttgggtca aaatttccag aagtaaaggt ttgattggtt tctttttgac
    25801 gatttttggg ttgatttcgt cgggaaggat tgagttgatt ttcaattttt tctttcactt
    25861 cttgatatac tttagaattt gtaccgataa gaacaccagt atcttttaga tataaatcag
    25921 caaattctgc catgatttct gtcatgatag aaatttcttt tcccatggca ttgagttttg
    25981 cttggttact ggttgtggtt gtattggtat caggttcata actcatacat aaaaagcgaa
    26041 tggcttctga ataattgtta acgtctggat ttttttcgat gatggaatct aaaacgtcaa
    26101 cgtgactggg ataaagggtt acgtgttttt gaacagaagt ttttctcatg ttatattcct
    26161 ccgataagtg tttcaatgag ttggttgttt gtgtgaacat agtcatttag tatgttcgta
    26221 ttttctgctt gaatggcaat aaatttttcg aataataaat cgaattgatc ttttttgtaa
    26281 ttcataagtt cgtggtcaaa atcgttttcg attaaaattt ttaggtattg atttcgactc
    26341 cattttttgc ccgttttggt tgttagttcc tgacaacgtt tatctattct tgtaataatt
    26401 ttgggattga tatttcgaac taaaatgtcc atggaaattt tcctttcgta tcagtgtata
    26461 atttatgtat atcatacaaa tatagtattt gtatagctat ttttcgccaa aacactatac
    26521 atagcctagc cacaatggca aaaaagtgat agcaaatttt tttctgagaa acgtgatagg
    26581 cacagcttat ctagcacctt tcgtaagaaa gtgataccac gtttccttat gctctttcaa
    26641 aattcagaaa aatcagctgt aaaacgagtg cagtccgagt aagattcaac gaaaaaacgg
    26701 ggattggggc gccaccaaaa tatcgcaaca tgggcccatg ttgctctgct cgcaaaagaa
    26761 aaaagaagaa taaaaccagc aatttttatt aatttaaatt gctggtttta ttgccagaat
    26821 tgccaccatt ttttctccgt ctttgattgt ttttctatcg attctgtttc ttcagaaaga
    26881 gtcgttgatt tattttccga agattcttcc gtataagtca actgtagttg ttcctgcagt
    26941 ttctcgattt gttggttggc ttgcagggtg agttgttgtt gttggtcgag taatttttgc
    27001 atttgtttta tttgctcgtc tttttcttgt agttgcatat ctttttgatt taactgttgt
    27061 tctaggagag aaaggacttc taattcggga acttggttgg cgtttttgtg gttttcggtt
    27121 ttagtttttt cgccaactag ttgttgattt gagttttcgt tttcgttaaa aaacattgat
    27181 tttatagcct tttgtccggt ttcattaatc acaaacttgt ttccgatttt cgaaaaccaa
    27241 agttttcgat tttcgtcaga aacttttttg ttaattgctg ttttactaac tcctaattct
    27301 tcagcaagtt ctttgattgt tttttctgtc ataaaatcta aaaacccctc aatctttgaa
    27361 taagttttga agattgtcta ataagtcttt ttttagttct gaaggaatat cggaatttat
    27421 ctctgatttt tgtgcattat tttctttatt ttgggtattt tgttctcttt ctaacttttc
    27481 taactgttgt aaaagttcca attttcgctt ttgttctttg attttttctt gtaatgaagt
    27541 aggtgctttt tcagattgaa cttgttggtt agctagttct aatgctttgt tttgttcttc
    27601 ttttgttggg gcatgtttgt taaagtcgtc tgattttttt atctcaggtt taaatgtaaa
    27661 ttggttctgt tgcaaagttt taaataaaga ataaaatccc ttacggtatc tatgatttaa
    27721 gctgggattc ccaataatac cttgatttca gtacagaccg aaaacccgaa gagagtgcct
    27781 tcttttcggg ttttcttata taatcctcga atggcttcca tgcctttaat cgtggtagag
    27841 gcagtgcgta aacttcgata gaatttattg cgtctcttta ctggacgatg gtcttgttca
    27901 atcaaattat tcaggtattt aatggtacga tgttctgtcc cttgataaaa gccgtattct
    27961 tttagtttct taaaggcact tgtaatagag ggggctttat ctgtgactac aaccttcggt
    28021 tcatcaaact gcttcactaa ccgcttaaga aaagcatagg ctgcttgtgt gtcccgtttt
    28081 ttacgtaacc aaatatccaa ggttaaacca tctgcatcga tggctcgata caaataatgc
    28141 cattttcctt taattttgat gtacgtttca tccattttcc atgaataaaa ggatttttta
    28201 tttttctttt tccaaatttg atagagtagt ttgccatatt cttgcaccca acgataaatc
    28261 gtcgtatgag aaacgttaat gccacgatca tataagattt cttgaacttc acgatagcta
    28321 aggttataac gaagatagta gcccacggct acaataatca catcctgctg aaattgcttt
    28381 cctttaaaat gattcatcgt cattcctcct gctatctttt tctattattc taccttattt
    28441 gatagtagat ttaaaacttt gcaacagaac caacggaatt aacagtcaaa tatcaaaatg
    28501 aattgaattt agtaccgctg aaaaatttca atgctaagca gatggattta ttttttgcat
    28561 tatgcgctcg tatgaaagat cgtggtttga aaaaagttag attttctttc gaggaattaa
    28621 aagagttaag tgattataag atgactgcta caaaagcctt tgtcggtgat ttagaaaagc
    28681 tctataaaga tatgcttaat cttacttacc gtactgaaga tgaggattct attcgctact
    28741 ttgttttgtt tactggtttt gaaatcaata aaacaaaaaa gtttgttgaa gtcagtgtta
    28801 atccggacct agaatatatt attaatggtt taacagctga atttagtaga tttgaattat
    28861 ctgctttcac gtcgttgcgt tctacgtatg caaaaactct attccgactg cttatgcagt
    28921 accgttctac tggttattat gtagttcgta ttgaagagtt taggagctta atggatatcc
    28981 cagaatacta tcaaatgggt aacattgatc aaaaagtatt aaatcctgca ttacgagaac
    29041 taaaaaaata cttcaatgat cttaaagtca caaaaataaa agcaaaaaag ggcaataaaa
    29101 tcgccaaatt agaatttact ttttcaagcc taacgtcaga tttgccaaag atttctctgc
    29161 gtaactggtt agaagaataa ataaaaaaga actcgccccc cttacattaa gcaagtagac
    29221 aagtccctta caaccgacta agattgctag tacattctag catattgtat ggggcttcta
    29281 aataaaaaac agataggaat aactcctatc tgttttttat cgttttagaa aatttgttgg
    29341 gtcgaaattt ctagaagtga ctgtttgact ggtttctttt tgatgattct ttggtcgatt
    29401 tcgatttgat ggatttagtt tagcttcgat tttttctttc acttcttgat atactttaga
    29461 atttgtgcca ataagaacgc ctgtatcttt tagatataaa tcagcaaatt ctgcgatgat
    29521 ttcagtcatg atggaaattt cttttcccat agcatttagt tttgcctgat tgctggtagt
    29581 ggtcgtgttg gtatcgggtt cataactcat acataaaaag cgaatggctt ccgagtagtt
    29641 attgatatct ggattttttt cgatgatgga atctaaaacg tcaacatgac tagggtacaa
    29701 agtaacatgt ttttggacag aagtttttct catggttata tcattcctcc gataagcatt
    29761 tcaatgattt gattatttgt gtagacatac tcgcttaata tttgagtatt ttctgtttgg
    29821 atagcaataa atttatcgag caataaatcg aattggtctt ttttgtaagt cgtaagttga
    29881 cggtcaaaat cactttcgat taaaactttt agatatttat ttcgactcca tttttctcct
    29941 gttttattcg tgagttcttg gcaacgtttg tctattgttg caacaaactt tggatcaata
    30001 ttccgaacta aaatgtccat aaaaaatctc cttttgcaat tatgtataat ttatgtatac
    30061 catacaaata ctatatttgt atagctgttt tttgccaaaa tgctatacat aagctaccca
    30121 cgatggcgaa aaagtgatat caaatttttt tctgagaaac gtgataggca cagcctatct
    30181 acccactttt tttagaaagt gggtacacgt ttccttatgc tctttaaaat tcgggggggg
    30241 gagtgctgca cgtgtaatcg ataaccaaat ttaaaaatgc acgatcaaaa atttatttag
    30301 tttttcaaac gacatttttt ttgagagtat agacggcaaa gaagtgattt tatttctaga
    30361 aaaattgtga gactggagaa agaaaaaatg gaaaaatttc cttacgaata ttttcaaaac
    30421 ttagaaaaat tagagcaagc aattcaagca atcaagttcg atttaacaga cgaaaaattg
    30481 ttggaatata aaaatatgac acccgaaaga aaacgatcgt tggaaaaatt aatgcaacta
    30541 gtgaacgaag acggcggaat ttcagacgca gcttttgacg catggagcga atttcatgga
    30601 gaatataatt aagtgggttt aaatggctct aaaatcgctt ctaagagttt tttagcttgg
    30661 accaatgaaa atacaccaaa aactaaataa aacgtcttaa atcgaaaaat acgagctctc
    30721 agagcgactt tatttgtaaa tgttgcatat aagaaataat tacggatttt agacttttgt
    30781 aggatatttt tgaaataaat atttatttct gttataattt gattgcaaat aagtgaacac
    30841 gaaacacacg aaagccccag agaggtcgga ttctctgggg ctttttttgt gggctgagtc
    30901 gccttaatta agttttactt cttgtttcgg ttattcaacc agtaactgaa caaagcgctt
    30961 aaaagcccaa caagaaggga gcaaataaag ttagtgaaca cgaaacacac ctccttccag
    31021 tcgcaagact gtcggatagg cgacaatcaa ttatacaata aaaaagcaaa aataagccta
    31081 agttttttat tgccttgggg ttgttagggc ttgccctgac cgcctgtaag gcgctttaga
    31141 acgaaggaca tagtttttat cgaatcttgt cttagaacgg cttagacgag ctctcaggac
    31201 gccacaaagg agtccctaat gaattatttt tggcgaagga gcctaaaggc gactgctgca
    31261 agtaaaatgt gagagcgtag cgatcactcc ttcttacagc gaccataggg agctagattg
    31321 gcagtttaat atcatgcgcg aacctgttta ttttaaaaag tgggtgattt tttggcggga
    31381 aattttgctc gcgcgcgcgc gtttatttta tttatttttt aaagattttt tagaaccctt
    31441 tttagggggc agttgagcct tactctccca acggatacag aagggtacta acaacttttt
    31501 atctgagtac taacaacttt ttatctgagt actaacaact ttttatctga gtactaatat
    31561 ccttttgtat aataacaacc aacctattta cgagttggtt gttaaaggtt attatttatt
    31621 tgtaaggggg gaagaaagga atggatgaaa aaacggaatg gttctgttgc aaagttttaa
    31681 ataaagaata aaatccctta cggtatctat gatttaagct gggattccca ataatacctt
    31741 gatttcagta cagaccgaaa acccgaagag agtgccttct tttcgggttt tcttatataa
    31801 tcctcgaatg gcttccatgc ctttaatcgt ggtagaggca gtgcgtaaac ttcgatagaa
    31861 tttattgcgt ctctttactg gacgatggtc ttgttcaatc aaattattca ggtatttaat
    31921 ggtacgatgt tctgtccctt gataaaagcc gtattctttt agtttcttaa aggcacttgt
    31981 aatagagggg gctttatctg tgactacaac cttcggttca tcaaactgct tcactaaccg
    32041 cttaagaaaa gcataggctg cttgtgtgtc ccgtttttta cgtaaccaaa tatccaaggt
    32101 taaaccatct gcatcgatgg ctcgatacaa ataatgccat tttcctttaa ttttgatgta
    32161 cgtttcatcc attttccatg aataaaagga ttttttattt ttctttttcc aaatttgata
    32221 gagtagtttg ccatattctt gcacccaacg ataaatcgtc gtatgagaaa cgttaatgcc
    32281 acgatcatat aagatttctt gaacttcacg atagctaagg ttataacgaa gatagtagcc
    32341 cacggctaca ataatcacat cctgctgaaa ttgctttcct ttaaaatgat tcatcgtcat
    32401 tcctcctgct atctttttct attattctac cttatttgat agtagattta aaactttgca
    32461 acagaacctt tgagggaata tgtagaagaa gtagataacc caggcgacga ctggtacacg
    32521 actttaactg attttttaga cacctatact tacgacgata cagaagaaat ccaaaatgaa
    32581 cttgaccgta aacgaatgcc atatcaacga tttgaaagga aaaaaaggca ataatcattt
    32641 ataccgaaaa gtgagaatgt gtgaaataag gacaaaaaac ctagtaacta agggaatggt
    32701 tcttatttcg caccaatcgc tccaaccgcc cccgccgctt aggtggtgcg aaataagcgg
    32761 gcaacacccg ataacctaag agaaagaagg agatccatat gaataaaatc attcctctat
    32821 tgttagtcct atttgttggc gaaatactta tgcgccatgc tgcagctgtg catttaaact
    32881 tcgtagtatt tttggcaata ctggtatttt gtttgatctt ttggcgcttt gtattagccc
    32941 ttgtgagtct actattcaag atgattgcag ccatattttt catagggtta tttcgatgaa
    33001 aggagagagt actaatgcca attgcaatag gaaataaacg gttacccgtt acgttggatg
    33061 aaaagagaca aaaagaattg cagcaactaa agcagaagta cggcaaaagt gaatccagga
    33121 ttatgtgtat tgcgttagat ttattgattg cccaagaaaa agcaggattt gaggtaccag
    33181 cactcaaaaa gtgacgtcac tttttatcct aaaaactaaa agtgatagca cttttaatta
    33241 taagaagtta gaatattaat catttgctta attgtacaat ataatgtaca attgttttat
    33301 agaaataaat aaggggtgaa aggaatggaa gcagtagctt attcaaattt ccgccaaaat
    33361 ttacgtagtt atatgaaaca agttaatgag gatgctgaaa cacttattgt aacaagtaaa
    33421 gatgtagaag atacagttgt tgtattatca aaaagagatt atgattctat gcaagaaacg
    33481 ttgagaacac tttctaataa ttacgtcatg gaaaaaattc gtcgaggaga tgaacaattc
    33541 tccaaaggtg catttaaaac acatgactta atcgaggttg aatctgatga ttaaggcttg
    33601 gtctgatgat gcttgggatg attatcttta ttggcatgag caaggaaaca aaagcaatat
    33661 aaaaaagatt aacaagttaa taaaagatat cgatcgttcc ccctttgctg gattaggaaa
    33721 acctgagcca ttaaagcatg atttatctgg aaaatggtcc agaagaatta cagatgaaca
    33781 tagactgata tatagagttg aaaatgaaac gatatttatt tattctgcaa aagatcacta
    33841 ttaaccaatc ggaagtaagg aaagggtcag aaacttaaaa gtttttgatc cttattttat
    33901 ttaccctagt catttaaaaa gctaatatag cttagtgttg attgttatta atgaatgtgt
    33961 ttgttacgcg tattacggat ataaggttag taaaatcatt tctaaagttg aggaaaagta
    34021 aatataaatg gcttaaattt caacaatttg aagttgaata gatatgttat aatactattg
    34081 tagtgtggga tgttagttac taaaggatga cgcttatata tatgactgaa tagaataagc
    34141 aataggttta ataatctatt ttaaattttt tgtactagtt ttagttaatt agcaaaaaca
    34201 acaaaaataa acttctcata gaatttagct aaaaattaat gatttattta catattaaat
    34261 ttggatacag ttaagtaatt tttatatatt ggaggagaag taatggaata taaatttaac
    34321 ttgaatttga aagaagtact ccccactcag ggaacaataa acataaatgg tcaagataat
    34381 gatgacgata tagtaataaa aaaatagaat ttattgattc tgatataaat gttttttttt
    34441 attctaaaga aaaattagct gattttagca atattgctga aatgattgaa cgtttaaaag
    34501 attttatgat cagtgtttgg gatgtagcga tgcttgctga cgaatcaaat tatacttcga
    34561 gcatatacag attagaagat agtaattgga tagaaatttc attagagtta aagacacttc
    34621 ctaattccgt taactatata attagagata taacttctga agctcaacaa ttagttaatt
    34681 acatgcatgg acacgaaagt atcccctttt ctcttatact ccttaaaaga agtaaaaata
    34741 tatcaaatac tagagatagg tttatttcga taattacagc ctgtgaaata ggggtaaagg
    34801 aattttatca acaagagaaa cctgatttaa ctctaatatt tgagaattta caatctcccc
    34861 ctgtagacaa attattaggg agcatgttta aagggtactt taatattgag tttccgaaag
    34921 aaataagaaa ggaaattaaa aatttcatag aaaaacgtaa taaattggtt cattctcctc
    34981 aaggaagtaa accaactata gaagaatgtt ttgaatgtta tatggcagtg ctaaaaacat
    35041 ttaatttttt ttataaaatt aatgatagct ttatgtatag agatttttat gaagaatcta
    35101 tagaattgac tccaacggaa ccaaataaat ctcaaatcac tttgtcaaag gagctagaga
    35161 gaaaagtaga gtctcaagaa ctagctatag gaattagtat aaccaatgtg tcgacataca
    35221 aagaattata cgaagctaaa tcacaagata ataaggattt tgtagaaaat atagataagg
    35281 aaccaacaaa tacagtaggg gattaacgta aataagtgaa gattatatta acagactctt
    35341 tatttagtta agtaaaaaat ggtttgttgg aattttatgc tttatctgtt ctgagtaaga
    35401 cttaatttta tagatagtaa ttatatgtag gaaattaaag atgagaagat aataaaagca
    35461 gcatgatcaa ctatttgtca ttgaccatgc tgtctttttt tattctatac acggtttgtc
    35521 tcgtaacatt gtagtcttta gcaatcttag caatcgcaac accattttta agatcttcaa
    35581 cgatgctttt gtaaacaagg cgacgttggg gatcttttgc gtctgcactg tataatttgg
    35641 gccgcccttt gtagacgccg tttgcttttg cgatcttaat tccttgtgcc tggcgacgtt
    35701 tcgattcagt ccgttcttgt tcagcgatca tggccaaaat ttggatgatc agatccttaa
    35761 tgaatttatc caggagagga ttgccaattg cttcagccat gatcggtaaa ctagtaatga
    35821 tcagcttcac atttttcttc ttcaagtaat tgactgaagc gatgatctcg tcataatttc
    35881 ttccaagtcg atcaatagct tccacaataa aaatatcttg atctcggacg taatctaatg
    35941 cttcttggaa aacaggtcga tgagtaatcg ttgcgccaga ttgtttctcg atgaaaattc
    36001 tctctgcacc gaattttttc atttcttcaa tctggcgttg ttcattttga tcgatcgatg
    36061 agacacgtat gtatgcaact ctcaaaactt ttacctactt tctgcaacta tttaaaatac
    36121 accctaatca tacacgagga agccatatgt cacttttctt tttaaatggc aatatttttt
    36181 gtaaataaat gtcaatcaag aaaatttaaa cgattatgac attaaaaata tattttatga
    36241 attttctagt atataacttg atttatctgt taagatttat taagaaaacg ttttcttagt
    36301 tttgatttcg aggtgataga caatgaaaaa taagtttatt ttatctttag gtattttaac
    36361 tattggaatt agtgtaactg gaactacaat tcctacattt gctgatagta caaatgaacc
    36421 aactactgta gtagataata accaagaatt aactccttta gatagggacg gaatagccat
    36481 tggtaaccca actaacgact taactgttac tgaaaattat ttaatagttt ctccattact
    36541 tgctctagca gcttctaaaa cgatacgagt gacaggaacg atgatttttg ataaagttgg
    36601 ttggccttct agacctcctc aatcacggaa ttggaaagaa aaaagaaatg gttattggta
    36661 ctatggaaaa ttgtatttac aaagttataa atcagctgga aacaattgga ttgcgactta
    36721 ttcaggaacc ttaactagaa agtagggatt ttttatgcca gaatttgtga acacaccaaa
    36781 tttttatcaa gatagcgata ttctaagtaa aattaattta ccgaaagaag aatcagcttt
    36841 acaagttcag cgaactttac aggagacaca aaaaattcaa aaatcaattt ctaatctaga
    36901 agattctgaa gaaaaaagaa aaaaaagaga ccaaaaaaca tatcaaaaag aaaaataatg
    36961 attttaaaaa aagagtgtct agtcgacatt ctttttttct aattgaaagt gttcataaaa
    37021 tcacccattt ctggacactt tctttttttg ctttattttt caaaaaaaca attcatttca
    37081 tgttcataaa cccataacaa tatctatgtt cagttaaact atatggataa agttatgtta
    37141 caataaaatt aatgaaggag tgattttttt gaaaatagga tacgcccggg tatctactgg
    37201 tttacaaaat ttggatttac aagaagacag cctaaataaa tttggttgtg aaaaaatttt
    37261 tactgatcat atgagtgggg caaaaagtaa tcgaccagga ttagaaatgg ccattgattt
    37321 tgttcgctct ggcgatacac ttgtcgtttg gcgcttagat cgtttaggta gaaatatgga
    37381 agatttgatt tcaatcgtca atcgactgaa tgagcgtggt gtgagttttc atagtattca
    37441 agaaaatatt acgatggaca aatcaagttc tacaggacag ctcatgtttc atttgtttgc
    37501 ggcatttgca gaatttgagc gtaatttgat cctggaacga tccgcagcag gacgagcatc
    37561 tgctcgtgca agaggacggt ttggtggtcg tcctgaaaaa ttgtctgaac aagatttgga
    37621 attactgaag actttagtgg atagcggtac acctattaag actattgcgg aacggtggaa
    37681 cgtctcaaga accaccattt atcgttattt ggcaaaaatg gaggagaaaa atggaaagac
    37741 aaattctcat tagtttttgt catttaatgc tgaaaatttt tgccatttat ctagaaaagt
    37801 gacaatagta tgagaatttt ttgtaagtgt ctactgataa cttattctca aatatttagc
    37861 tatttcttct ttacaacatc gaacatatgt ttgtataatg tggaagaatg gagtgttatt
    37921 tatgatggat tattcaaaag agccagtaaa tgattacttt ttaatcgata tgaaaagctt
    37981 ttacgcaagt gtcgaatgta tagaaagaaa tttagatcca ttaacaacag aacttgttgt
    38041 tatgagtcga tctgataata ctggttcagg attgatatta gcttcttctc ctgaagcaaa
    38101 aaagcggtat ggtattacaa atgtgagtag accacgtgac ttaccacaac catttcctaa
    38161 aacactacac gttgttccac cacgtatgaa cctatatatc aagcgaaata tgcaggtaaa
    38221 taatattttc agaagatatg tggctgatga agatctactg atttactcga tcgatgaatc
    38281 gattttaaaa gtgacaaaat cactgaatct ttttacgact gaagaaacac gaagtcagcg
    38341 aaggaagaag ctcgctcaaa tgatccaaga acgtattaaa gaagagttag gtttgattgc
    38401 tacggtaggc gtcggcgata atcccctttt ggctaaatta gccttagaca atgaagcaaa
    38461 gcataatgaa ggatttattg cggaatggac gtacgaaaac gttcctgaga aagtatggaa
    38521 tattcccgaa atgacggact tttggggaat tggttcgcga atgaaaaaaa ggctcaacca
    38581 aatgggaatt ttgagcatta gagaccttgc taactggaat ccttatacga ttaagaatag
    38641 attaggtgtg attggattac agctgtactt ccatgctaac ggaatcgatc gaacagatat
    38701 agcaatcccg ccagaaccga caaaggaaaa atcttatggt aattcacaag tgttaccacg
    38761 agattatact agaagaaatg aaatcgagct ggtggtaaaa gaaatggcgg aacaagtagc
    38821 cattcgtatc aggcagcata attgtaaaac aggatgtgtt catttaaaca ttggtacgtc
    38881 gatcttagaa acgagaccag gattttcaca ccagatgaaa atacctatca cagataatac
    38941 aaaggaattg cagaattatt gtcttttctt gtttgataag tattatgaag gacaagaagt
    39001 aaggcacgtt ggaataacct atagcaagct tgtgtacacc gattcgcttc agctggattt
    39061 atttagtgat ccacaaaagc aaattaacga agaaaattta gataaaatta ttgacaagat
    39121 tcggcaaaaa tatggtttta cgtcgattgt acatgcttct tcaatgttag aaagcgctag
    39181 aagcattact agaagcacac ttgttggtgg tcatgcgggc ggaaatgggg gaattaaaaa
    39241 tgattgatta caatgatcgt ggacgtttaa agtgggcagg gttttattta tctgatcata
    39301 ctgaagaaat tgatgccgac aatgaacaac gaaccagtca aaatttagca aaagaacaaa
    39361 tgacgactga agagattgcg gaagtattga acgctgcagt cataaaaaat agatcagtat
    39421 ctattcaaaa agaagaacga aacgctgaag gatactatcc agaagatatc attggcaaga
    39481 tcttaggtag tgatgagctg gggatctacg ttggaaaaga caaaattcac tacgacgaaa
    39541 tacgtcatat cgaattttac caggataata aatggagtcg attagaatga acattatcca
    39601 gcaatatgag ctaaagtata taacctttga tcagctatca gaagagattt ggggttatgg
    39661 ccaacgtttg ataaatgagg ttggtgttga gcgcttctct ttctatgtag aagctgcagc
    39721 aggttatcat aattttaggt tttatatctt cccgttatat atataaggta ttttacggat
    39781 tctatagagt tatctctatg aatccttttt tgtttttaca aataggagta gatactagaa
    39841 taatgcgtgt gttaaactat tattgcaaac gcaataataa aagaaagtag gcttacgcac
    39901 catgtctatc aatacatttg tttactcgca cccgatcaat gtttacatta tcaagaattt
    39961 aggaatcact gtagaacaat tttgtgagtt atatgcctac ccacaaggaa cggttgcaag
    40021 ctggataacc cgacaacgta gaataaaatc attacctgct tcattcgttt atgatttaag
    40081 cctggcctct agtttaaaca tgtctgatgt ttatgaaaag ctcctgtctt tagaaaaaga
    40141 atatgattcc ttcaagatta aacatgataa aaaaataaaa aaacatatat aatatcaatc
    40201 acaattgtat aatattacga tatcttaata tcatgatatc gtaatattgt ttttttctaa
    40261 gaaaatgcac tataagaagg gaattattag taacaatata gacagtttag taatgtttaa
    40321 attattctag ttgctgctcg caaaacatat ttcttatcat taataaaaaa ttttaaagta
    40381 ataaaaagtg attattttaa tttcgaataa catatgaata atctttatat ccgaaccgat
    40441 atatatcttt aaaacaaaat aatcacacaa tattacaata taatgcatat acgatattgc
    40501 aatatcacaa tattatgata taattatatt ataatataag atgaatgggg gatattttaa
    40561 tggcaagaat attgtcagta gccaatcaaa aaggtggagt ttctaaaact acgactagcg
    40621 ttaatttagc agcatgtttg aaatttgttt acggtaaaaa tgtactttta gtggacattg
    40681 atcctcaggg aaatgctaca gataatgtag gtttcgatat agatggaaca aaccaaccta
    40741 caatttatga agtattaaaa ggggaggctg acattacaga tgctattctg gactataaag
    40801 gaattgatgt tttgccagcc gacatagccc tttcttctgc agagagggaa tttactcaag
    40861 taggaagtga acacaggctt aaaagagtac ttcaaccaat caaggacaac tatgattata
    40921 ttataattga ttgtccacca agtttaggaa tgcttacagt caacgcattt actgtttctg
    40981 atgaaattat cattccagtt gaagctgcgt atttctcatt aaaaggacta ataaagttaa
    41041 gtgaaactat tgaaacggta aaagaatata cgaacgacaa gcttgaagta cgaggagttc
    41101 tatttactaa gtataataag cgttataaca tttctaaaga aatgacgtct gcagcaaccg
    41161 aaatttctag agtcattggt gcaaaaattt tcaaaactta tattcgtagg acaataaccg
    41221 ttgacgaagc gcaagctgct ggatcagatc taatcaattt taataaaccc tcaacagctg
    41281 aagatgacta taaagcattt acagaagaat atttaaaaga agttggtgat tttgatggca
    41341 gaagataatc gcagtcaagc tgcagtaagt agattactag gaaataaaaa taaaaagaat
    41401 tttaaatcaa aagaagtaga agaaatcgaa ttaaccaaga aaaatataag taaagtcata
    41461 aaagatcaag gaagtagtgt aagaacagca gatagcattc gtataaatcc aattctaatg
    41521 tcagcactca aatattggac gactattgct gaatcagaca aaagtaaacc agacgttata
    41581 gaagatgcgc tattaaagtc catacctgaa gaatacttga ttgaaggata taaactagca
    41641 aagaaacaaa ataaaattta atttacattc aatatcacga tatcataata tcgtgatatt
    41701 ttttttataa aaatcagtag tatcaaagct gataagtcgc ttatcttcat attgtaatat
    41761 tacgatatcg tgatataata ttattgtaat atcgtgatat agttactatg agcttaaacc
    41821 ttgaaataga gcggtttgct ttaatttatt ttttaaggta aactaaaaaa agataaaaaa
    41881 agactactgc tttaacaaag tttggcgact tatcagcagt agaaaaatat atagtggata
    41941 gatatatttg tttaattcat tgtaacatag ttttgaacaa aacgctatcc tacagaaaga
    42001 ggattggct
//
