LOCUS       NZ_CP094874            30678 bp    DNA     circular CON 20-APR-2024
DEFINITION  Staphylococcus epidermidis strain C101 plasmid pC101MK1, complete
            sequence.
ACCESSION   NZ_CP094874
VERSION     NZ_CP094874.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN27161490
            Assembly: GCF_022832935.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus epidermidis
  ORGANISM  Staphylococcus epidermidis
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 30678)
  AUTHORS   Kopczyk,M., Mulroney,K., Chakera,A., Ramsay,J.P., Colombi,E.,
            Coombs,G.W. and Mowlaboccus,S.
  TITLE     Sequencing of Staphylococcus epidermidis isolated from peritoneal
            cavity
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 30678)
  AUTHORS   Kopczyk,M., Mulroney,K., Chakera,A., Ramsay,J.P., Colombi,E.,
            Coombs,G.W. and Mowlaboccus,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2022) School of Pharmacy & Biomedical Sciences,
            Curtin University, Kent street, Bentley, WA 6102, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-MAR-2022
            Assembly Method :: Flye v. 2.9-b1774; Racon v. 1.4.15; Pilon v. 1.23
            Assembly Name                     :: C101MK-10-Mar-2022
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 306.0x
            Sequencing Technology :: Illumina NextSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022832935.1-RS_2024_04_19
            Annotation Date                   :: 04/19/2024 10:01:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,422
            CDSs (total)                      :: 2,338
            Genes (coding)                    :: 2,264
            CDSs (with protein)               :: 2,264
            Genes (RNA)                       :: 84
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 46 of 74
            Pseudo Genes (incomplete)         :: 36 of 74
            Pseudo Genes (internal stop)      :: 27 of 74
            Pseudo Genes (multiple problems)  :: 26 of 74
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP094874.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..30678
                     /organism="Staphylococcus epidermidis"
                     /mol_type="genomic DNA"
                     /strain="C101"
                     /isolation_source="pertoneal cavity"
                     /host="Homo sapiens"
                     /db_xref="taxon:1282"
                     /plasmid="pC101MK1"
                     /geo_loc_name="Australia: Perth"
                     /lat_lon="31.92851574 S 115.86399442 E"
                     /collection_date="2017-04-28"
                     /collected_by="Harry Perkins Institute of Medical Research"
     gene            1..954
                     /locus_tag="MUG62_RS11855"
                     /old_locus_tag="MUG62_11855"
     CDS             1..954
                     /locus_tag="MUG62_RS11855"
                     /old_locus_tag="MUG62_11855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017175392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_002500634.1"
                     /translation="MSRKNIKNQANQNFYMLHKALFVNEKYKKLSDSAKVTYAILNDRV
                     SLSIKNNWVDDNGDIYFIFTNESLQNILDKSKNTITKIKKELQAVGLLEQIRTGFNKPN
                     KLYLHDIETNINVEKSIQSSSITYNDKDSQILGLQNPEFWDSRFSKFGSPESQILDPND
                     TDYNDTDYIKTENNDTDDLNDNKLTFPSNHTNHSNHDNSNFNNEALKFQLLEELPQSIQ
                     NYLSNFEVAEIKIIKTVLLKAKTSFNNAIDSYYLLEDMEIEILHVLKRFKAMLIQKNET
                     VVSMQGYLMKSLKSEFAEMHTLNKRRDHLPITSLFN"
                     /name="replication initiator protein A"
     gene            2759..2854
                     /locus_tag="MUG62_RS11860"
                     /old_locus_tag="MUG62_11860"
     CDS             2759..2854
                     /locus_tag="MUG62_RS11860"
                     /old_locus_tag="MUG62_11860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_000493115.1"
                     /translation="MFSTLFVTIIAPIVVGVILTLFSHWLNNREK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            3104..3652
                     /locus_tag="MUG62_RS11865"
                     /old_locus_tag="MUG62_11865"
     CDS             3104..3652
                     /locus_tag="MUG62_RS11865"
                     /old_locus_tag="MUG62_11865"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002441962.1"
                     /translation="MKKVKSYLKNIQNNEEYQKDIEFLEKKSNGREDKKLILDICFLST
                     IPLISIYITYFLSFSNPFAIFILIIIAVPVSYKIAKILLDHMYKDEDRFLALYRNYEKG
                     KLLFLTLPIIGLVSIIGSSFLFDYLIFKLNNTSVEILGSTPTVVYHIIICFIQSMFTTM
                     FLIIFIYTILVLIYGRFTK"
                     /name="hypothetical protein"
     gene            complement(3729..4256)
                     /locus_tag="MUG62_RS11870"
                     /old_locus_tag="MUG62_11870"
     CDS             complement(3729..4256)
                     /locus_tag="MUG62_RS11870"
                     /old_locus_tag="MUG62_11870"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="WP_001831394.1"
                     /translation="MIKFEYFEEKDFDLLINWINSPELLVKWAGTDFNYPLDEEQLKEY
                     IKDTNKENSSKIIYKVIIEENNSKKIIGHIALNNIDFKNCSATLSKVLVGDPQMRGQGL
                     GPKIIKKLLKKAFEDLGLHRIELGVFAFNKSAIKSYKKIGFIKEGEKRDFRKLNGEYYN
                     LWQMSMLESEWS"
                     /name="GNAT family protein"
     gene            complement(4449..5105)
                     /locus_tag="MUG62_RS11875"
                     /old_locus_tag="MUG62_11875"
     CDS             complement(4449..5105)
                     /locus_tag="MUG62_RS11875"
                     /old_locus_tag="MUG62_11875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002489266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001831384.1"
                     /translation="MNHNHEYHSNKPEIKANVVYRDGNIEITLEDEFNNAPLLDTMHEK
                     EMHFVLVSNDMEKYYHLHPQKKHEGLFIINQQLEPGTYQAFVDVTPKNHVYSVHPIELQ
                     IGDKITSTTSLNSDKNWVKVNKGVHVTLNSISAKEDEHVPLTFNTELTPQPYLGALGHV
                     IIFDEQLTDYIHVHPESPDSTTFYAHFPKKGMYKIWAEFKFNDEVHRFTYNIKVA"
                     /name="hypothetical protein"
     gene            complement(5169..5378)
                     /gene="copZ"
                     /locus_tag="MUG62_RS11880"
                     /old_locus_tag="MUG62_11880"
     CDS             complement(5169..5378)
                     /gene="copZ"
                     /locus_tag="MUG62_RS11880"
                     /old_locus_tag="MUG62_11880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001831373.1"
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="WP_001831373.1"
                     /translation="MTNEVINVEGMSCDHCKHSIEKALNGLDGVTSSEVSLANGNVEVE
                     FDENQVAFNDFKEAIEDQGYDVIK"
                     /name="copZ"
     gene            complement(5412..7799)
                     /locus_tag="MUG62_RS11885"
                     /old_locus_tag="MUG62_11885"
     CDS             complement(5412..7799)
                     /locus_tag="MUG62_RS11885"
                     /old_locus_tag="MUG62_11885"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002485948.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0019829 - ATPase-coupled monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="WP_001832797.1"
                     /translation="MSENIKKTSLGITGMTCAACSNKVEKNLNKLDEVNANVNPSTEKA
                     TIEYNPNVTSLEDIANTIQKTGYGVLTEKVDLDVMGMTCAACSNKIEKVLNRISGVNKA
                     TVNLTTESATVEYNPDMTSVDEFQQRIKNLGYEAQPKKEASEKSSQKEKQLKRQLIKLV
                     VSAVLAAPLLMTMFVHLFGIQIPHIFMNPWFQFVLATPVQFVIGWQFYVGAYKNLRNGS
                     ANMDVLVALGTSAAFFYSIYESIKWLINTNYEPHLYFETSAVLITLILFGKYLEARAKT
                     QTTNALSKLLNLQAKEARILRNGEETMVPLSEVKEGDYLVIKPGEKIPVDGKIIKGMTS
                     IDESMLTGESIPVEKMQNDNVIGSTMNKNGAITVEATKVGKDTALASIVKVVEEAQGSK
                     APIQRLADIISGYFVPIVVGIAIFTFIIWISLVQPGQFEPALVAAIAVLVIACPCALGL
                     ATPTSIMVGTGKAAENGILFKGGEHIEGTHAINTVVLDKTGTITNGTPEVTDFSGDDQT
                     LQLLASAEKGSEHPLAEAIVSYAKEKSLEFLEVDHFEAIPGRGINATIDGKELFVGNRK
                     LMSEKGIQTNEAETNLAQFEKEGKTAMLISVDNELRGVVAVADTVKDTAQQAIQKLHEL
                     GIEVAMLTGDNKRTAQAIAKQVGIDTIIAEVLPEEKASKVAEIQSEGKKVAMVGDGVND
                     APALVKADIGIAIGTGTEVAIEAADITILGGDLLLIPKAIKASKSTIRNIRQNLFWAFG
                     YNVAGIPIAAIGLLAPWVAGAAMALSSVSVVTNALRLKRMKL"
                     /name="heavy metal translocating P-type ATPase"
     gene            complement(7814..8089)
                     /locus_tag="MUG62_RS11890"
                     /old_locus_tag="MUG62_11890"
     CDS             complement(7814..8089)
                     /locus_tag="MUG62_RS11890"
                     /old_locus_tag="MUG62_11890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001831396.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0046872 - metal ion binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
                     /protein_id="WP_001831396.1"
                     /translation="MNTTTVKNNDALLNRLKRLEGQMRGLQSMIAEDRYCIDVLVQITA
                     IQSALKQVGFIVTEDHISNCVSEGIKNGNGEESIKELMVVLKQFSK"
                     /name="metal-sensing transcriptional repressor"
     gene            8264..8538
                     /locus_tag="MUG62_RS11895"
                     /old_locus_tag="MUG62_11895"
                     /pseudo=""
     CDS             8264..8538
                     /locus_tag="MUG62_RS11895"
                     /old_locus_tag="MUG62_11895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002489264.1"
                     /GO_function="GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin family protein"
                     /name="glutaredoxin family protein"
     gene            complement(8579..9520)
                     /locus_tag="MUG62_RS11900"
                     /old_locus_tag="MUG62_11900"
     CDS             complement(8579..9520)
                     /locus_tag="MUG62_RS11900"
                     /old_locus_tag="MUG62_11900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002449936.1"
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_001831389.1"
                     /translation="MENDHNHNHTHGANKKTLLISFIIITSYMIVEGLGGFFTNSLALI
                     SDAGHMLSDSISLGIALIAFTLGAKQANTNKTFGYKRFEILAAVLNGITLMLIAIYIFY
                     EAIERFKNPPEVASTGMLIIALVGLFINIIVAWIMLRGSDVEENLNMRGAYLHVISDML
                     GSIGAVIAALLIIFFRWGWADPLASVIVAILVLRSGFYVTKSSLHVLMEGAPSNINTKD
                     IIKTIKKFKEVKNIHDFHVWSVTSGLNALSCHIVVEDTMTITENEFLLKRIEHELNHQN
                     IQHVTIQTETSNNNHSEKLFCIVKEEDSQHHH"
                     /name="cation diffusion facilitator family transporter"
     gene            complement(9883..10281)
                     /locus_tag="MUG62_RS11905"
                     /old_locus_tag="MUG62_11905"
     CDS             complement(9883..10281)
                     /locus_tag="MUG62_RS11905"
                     /old_locus_tag="MUG62_11905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002449932.1"
                     /translation="MVSYIFYFATEPDNTIDYLKTILNKKTTKESTKFDEKSTNKTESL
                     NNQYSSYIDKYIEHLESEIRQKNRQIDDLTIALKQEQSLNLNSQNILSNTKKIETDNID
                     SKEDIITPKASKKNEQKQSIFSKLFKKK"
                     /name="hypothetical protein"
     gene            complement(10305..10979)
                     /locus_tag="MUG62_RS11910"
                     /old_locus_tag="MUG62_11910"
     CDS             complement(10305..10979)
                     /locus_tag="MUG62_RS11910"
                     /old_locus_tag="MUG62_11910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_058586762.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHRTSKYLN
                     NLIEQDHRHIKVRKTKYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            11042..11902
                     /locus_tag="MUG62_RS11915"
                     /old_locus_tag="MUG62_11915"
     CDS             11042..11902
                     /locus_tag="MUG62_RS11915"
                     /old_locus_tag="MUG62_11915"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002505095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="WP_002505095.1"
                     /translation="MQYLPKDVLKEIEFEFGDIMNYESIDKATNNADIIYNLAALVSVP
                     YSYKNSESFFDVNIKGLLNLLNSVNKKGTIERVIQMSSSEVYGSPQYTPINEAHPLQPQ
                     SPYAASKVGADALATSFYKTYGTPVTIARPFNTYGPRQSRRAIIPTIISQALHSSSLSL
                     GNIDSLRDFNYIDDTTSGLLALLEETTNQGAPINIGSGYSYSIKDIIDIVSKLLNKNLY
                     VNRDDNRIRPSKSEVSELLCDNTTISKLTSWKSNVSLEQGIQNTIAFFYKKDKNFIEKS
                     NNYFI"
                     /name="GDP-mannose 4,6-dehydratase"
     gene            11978..12609
                     /locus_tag="MUG62_RS11920"
                     /old_locus_tag="MUG62_11920"
                     /pseudo=""
     CDS             11978..12609
                     /locus_tag="MUG62_RS11920"
                     /old_locus_tag="MUG62_11920"
                     /inference="COORDINATES: protein motif:HMM:NF012695.4"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /name="sugar phosphate nucleotidyltransferase"
     gene            12621..13724
                     /locus_tag="MUG62_RS11925"
                     /old_locus_tag="MUG62_11925"
     CDS             12621..13724
                     /locus_tag="MUG62_RS11925"
                     /old_locus_tag="MUG62_11925"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF013227.4"
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="WP_244025953.1"
                     /translation="MWDIEVSSSDISQKDIEIVCETMKSNWLSMGPKVKEFESMWAKEL
                     GINYISAVSSGTAALHLACLCCEFTYGDEVIVPALTFVATANAVKYTGATPIISDIESK
                     DNLILSIEEIRKNITSKTKGIIIVHYAGYTYNIEEISKLAKEYNLYLIEDAAHAITSSY
                     NNKSLGTYGDLACFSFYPNKNITTGEGGVIATNNKDFHEKIRSLRTHGMTTETWNRYNS
                     SISTYDVNNLGYNYRMDDLRASLGISQFKNMKRNKIHRKNLVNKYRELLLGYKEITIPF
                     LTNNTDSSNYIFVIFVKNPILKEKMITDLRNEKIQTSFHYTPLHKFSYYKSKNLLPIVE
                     EVSKGLVTLPLHNRLSINDVKKGLHYY"
                     /name="DegT/DnrJ/EryC1/StrS family aminotransferase"
     gene            13755..14501
                     /locus_tag="MUG62_RS11930"
                     /old_locus_tag="MUG62_11930"
     CDS             13755..14501
                     /locus_tag="MUG62_RS11930"
                     /old_locus_tag="MUG62_11930"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081004.1"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]; GO:1904047 - S-adenosyl-L-methionine
                     binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_001081004.1"
                     /translation="MNRLNTNYFDNFYIDWQNNEISENYVEFCQKQINNLSHIVPSLKK
                     EKRKIIDTCCGCGFHSKFLIDKGHHVISFDKSEEMLNFAYKKNGILGKRQSLDEEFPEN
                     HVDLILNLNTSIGYKKNDLKNLLRNSYTSLKKGGILIIDLMNPAFFYKNFEEQMIFNFK
                     DYEVNQTIKINKIYNSIVSTWDVYKNNEYSKDLSRELKFKLYTTNDIICSSLYYNFTLS
                     NISFYGDMKGNEFHENSPRLIVKITK"
                     /name="class I SAM-dependent methyltransferase"
     gene            14528..17604
                     /gene="mupA"
                     /locus_tag="MUG62_RS11935"
                     /old_locus_tag="MUG62_11935"
                     /pseudo=""
     CDS             14528..17604
                     /gene="mupA"
                     /locus_tag="MUG62_RS11935"
                     /old_locus_tag="MUG62_11935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163435.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="mupirocin-resistant isoleucine--tRNA ligase MupA"
                     /name="mupA"
     gene            17674..18561
                     /locus_tag="MUG62_RS11940"
                     /old_locus_tag="MUG62_11940"
     CDS             17674..18561
                     /locus_tag="MUG62_RS11940"
                     /old_locus_tag="MUG62_11940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="WP_000282188.1"
                     /translation="MYNFDYSKLPIKNIQKIFPIAGGYVNLSFSVDASNKKYFLKLQPN
                     TKSNFFDYELSSLKELTDKNIPVPQIINKGELDNNSFLLLEFIENGHAYPESYRKLGKI
                     VANMHKNINSLNLFGFSHNFNGGTIEFTNKWTSSWGDLFIKSRMDKLCSEIYKKRLFSI
                     SDLLLYEDIRKIMLKSLYYHQSSPSLLHGDLWKGNILFQKNGDPILCDPVCLYGDREFD
                     IGYTLALEKFPLDFYQEYNNIYPLCVGYEKRIEFYKLYVFMIHLFAIGTDFYDKVKDTM
                     YNILNNYGVDFIKG"
                     /name="fructosamine kinase family protein"
     gene            18563..19735
                     /locus_tag="MUG62_RS11945"
                     /old_locus_tag="MUG62_11945"
     CDS             18563..19735
                     /locus_tag="MUG62_RS11945"
                     /old_locus_tag="MUG62_11945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001555828.1"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="WP_225791990.1"
                     /translation="MLTLFQFSKIIYLLLIVTFFERFSHFLIIPFLSIYLIQEFSYSSL
                     EIGIILSSSGCTALIISFILAPMLSTVNKKKIILCSIFTAFISFVIFPYIHSYYGFLFF
                     TIINTIASSLLSPTYKTLLTLYSETSRKRLVFNIRYYLINIAAALGPFISIQIQEVSSL
                     KNVCIFISFIYFINFIFFLFSSIEEKRSENPKLNYLTSFGIIKRNKAYVLLLLGSIFFV
                     FGYSQILSSIPQFFAIKSHSKATSIYGYLLSINGVIALTCQYFIYLLNKRYSHKSCIIL
                     GAITLTLGLFTFGLTENIVLLAFAIIVFTMGEMLVFTTIDIRIDEITDKYNKGAYYSLL
                     GLQNIGSLLAPVIGGLIITQFKSGMLIFSILSLITSFSIVLFYKSNKIKI"
                     /name="MFS transporter"
     gene            <19812..>19940
                     /locus_tag="MUG62_RS11950"
                     /old_locus_tag="MUG62_11950"
                     /pseudo=""
     CDS             <19812..>19940
                     /locus_tag="MUG62_RS11950"
                     /old_locus_tag="MUG62_11950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001106057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /name="DDE-type integrase/transposase/recombinase"
     gene            complement(19913..20140)
                     /locus_tag="MUG62_RS11955"
                     /old_locus_tag="MUG62_11955"
     CDS             complement(19913..20140)
                     /locus_tag="MUG62_RS11955"
                     /old_locus_tag="MUG62_11955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="WP_002440499.1"
                     /translation="MKYKVIREEKQRNPIIVTKYNRGYLVLDSAHRYTALKKIGCQYVM
                     CQVVEKDDYTIEIWNHQISHNDFLKISPNV"
                     /name="ParB N-terminal domain-containing protein"
     gene            22404..22499
                     /locus_tag="MUG62_RS11960"
                     /old_locus_tag="MUG62_11960"
     CDS             22404..22499
                     /locus_tag="MUG62_RS11960"
                     /old_locus_tag="MUG62_11960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_000889978.1"
                     /translation="MLEILVHITTTVISGCIIALFTHWLRNRNNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(22636..25179)
                     /locus_tag="MUG62_RS11965"
                     /old_locus_tag="MUG62_11965"
     CDS             complement(22636..25179)
                     /locus_tag="MUG62_RS11965"
                     /old_locus_tag="MUG62_11965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002487658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_002487658.1"
                     /translation="MIIDDIVKWIEEQPYWQQVIAKKILDKSHIYDEDIEDFFSIFMKY
                     NNLEHGNFNREKIEFRNITNTTDEHKIANWKGLDNVIGVNAIKDNANLVIGPQLTLIYG
                     ENGSGKSGFTRLLNNIFISRGDTRLLSNIFKDNPSPPSANINFETNDGNIDKLYYPKDS
                     NHPYTDHVSVFDSHSALHDLTQESELSFSPTEFKFFDKLLEIVQKLKEKFEAKINDKTL
                     DNTFINHFDKETSIKRLLLNLNTKDDFDELKIKVKLTENDMENHANNNKRISELQSMQI
                     FDKKQEYQNLISILEDVKKTIKKLNPLFSSAYLSEVKGLIEERNHYKDVSLTEGIAQFK
                     DENIEKLGSKEWKDFIESAYKYYTTINHSVNYCIFCHQDISNIKLIDKYWKYLKNESEK
                     ILAVKNNSIKKEERRFKLINTTILNKDSILSYFLKDDNIDLFNSINQASNNFESLKDKV
                     LKALNNLQWDSQIKGYNFDYNEIEKVINNLNNLIEDLDEDSVKKEIEELQIKENEFNDK
                     LKVEKLLPKIEDFINNKEWVDNASKIKINTRSITSKQNSLFSKYVTDTYIETFNNECQK
                     LNANFSAEIKQRGRKGTTLNKLTIQEKKPIDILSEGEQRAIALANFLSETSMNKNNVCI
                     VFDDPVSSLDHKRKEIIADRLIDEAQQKQVVIFTHDLPFLLLMQNKSSEKQLDCRHNTL
                     RKIKNETGISTNSHPWISMTVKRRIGYLKEQLQNITTYYNNISSDAPEEQLEYSYKAKM
                     WCEELRETWEKSIEELLLNGSIERFNPAIQTSRLKKAPFNRELYEEVEKGMTESSKWVH
                     DRSSALGEETPSPEQLKEYIDDLEKFTKKLKKLIK"
                     /name="AAA family ATPase"
     gene            25391..25999
                     /locus_tag="MUG62_RS11970"
                     /old_locus_tag="MUG62_11970"
     CDS             25391..25999
                     /locus_tag="MUG62_RS11970"
                     /old_locus_tag="MUG62_11970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583537.1"
                     /translation="MIIGYARVSSVDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEVINTVNYLKDKEVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIVQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKNGKGLS"
                     /name="recombinase family protein"
     gene            complement(26204..26770)
                     /gene="qacR"
                     /locus_tag="MUG62_RS11975"
                     /old_locus_tag="MUG62_11975"
     ARG             complement(26208..26770)
                     /name="qacR"
                     /gene="qacR"
                     /gene_name="multidrug-binding transcriptional regulator
                     QacR"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="99.47"
                     /coverage="100.0"
     gene            26948..28492
                     /locus_tag="MUG62_RS11980"
                     /old_locus_tag="MUG62_11980"
     CDS             26948..28492
                     /locus_tag="MUG62_RS11980"
                     /old_locus_tag="MUG62_11980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux MFS
                     transporter QacA"
                     /protein_id="WP_000622776.1"
                     /translation="MISFFTKTTDMMTSKKRWTALVVLAVSLFVVTMDMTILIMALPEL
                     VRELEPSGTQQLWIVDIYSLVLAGFIIPLSAFADKWGRKKALLTGFALFGLVSLAIFFA
                     ESAEFVIAIRFLLGIAGALIMPTTLSMIRVIFENPKERATALAVWSIASSIGAVFGPII
                     GGALLEQFSWHSAFLINVPFAIIAVVAGLFLLPESKLSKEKSHSWDIPSTILSIAGMIG
                     LVWSIKEFSKEGLADIIPWVVIVLAITMIVIFVKRNLSSSDPMLDVRLFKKRSFSAGTI
                     AAFMTMFAMASVLLLASQWLQVVEELSPFKAGLYLLPMAIGDMVFAPIAPGLAARFGPK
                     IVLPSGIGIAAIGMFIMYFFGHPLSYSTMALALILVGAGMASLAVASALIMLETPTSKA
                     GNAAAVEESMYDLGNVFGVAVLGSLSSMLYRVFLDISSFSSKGIVGDLAHVAEESVVGA
                     VEVAKATGIKQLANEAVTSFNDAFVATALVGGIIMIIISIVVYLLIPKSLDITKQK"
                     /name="quaternary ammonium compound efflux MFS transporter
                     QacA"
     gene            28697..29257
                     /locus_tag="MUG62_RS11985"
                     /old_locus_tag="MUG62_11985"
     CDS             28697..29257
                     /locus_tag="MUG62_RS11985"
                     /old_locus_tag="MUG62_11985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001077893.1"
                     /translation="MNRADIFKIFDVELNITIFLGALVATFIYFISYMNNVNELITLCL
                     TLAFPAYLLKISRSFEVILLEEKIKNSKIKICDKDRIEREILVKKNLIDELLFPNRVIK
                     KYTLTILIYSIGIIILLLLCNMLSYGIGENVNFIWRLLACYVTSVTVIIVALIIMIMIF
                     DLIIGLLLNFQIFLKNKKYDDFL"
                     /name="hypothetical protein"
     gene            complement(29580..30293)
                     /locus_tag="MUG62_RS11990"
                     /old_locus_tag="MUG62_11990"
     CDS             complement(29580..30293)
                     /locus_tag="MUG62_RS11990"
                     /old_locus_tag="MUG62_11990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002500633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_002500633.1"
                     /translation="MKSVKEISEELEVSKQTVFNNIKRLNIETVKQDNTSFIKNDVDVE
                     KIIQRVIRNKKKYGFESANVSSEKVKTDNKKNESKYDVQIIELLEKQIDTLNKQLEKQE
                     KRHETTIEFYRKELQERSKLLENQQVLALESNKKIQRLESELEEERQLNYSANKRQDIE
                     VQETMENMDSINNDSDSQKEKMVSHFRDESKDKHEDKQQDSELQQGNKIDGEQKEDIRN
                     ENHSKKSFWSKLFGN"
                     /name="DUF536 domain-containing protein"
     ARG             26949..28489
                     /name="qacA"
                     /gene="qacA"
                     /gene_name="quaternary ammonium compound efflux MFS
                     transporter QacA"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             15494..17604
                     /name="Staphylococcus aureus mupA conferring resistance to
                     mupirocin"
                     /gene="Staphylococcus aureus mupA conferring resistance to
                     mupirocin"
                     /gene_name="antibiotic-resistant isoleucyl-tRNA synthetase
                     (ileS)"
                     /tool="rgi"
                     /drug_class="mupirocin-like antibiotic"
                     /identity="99.29"
                     /coverage="68.65"
     ARG             14529..14788
                     /name="Staphylococcus aureus mupA conferring resistance to
                     mupirocin"
                     /gene="Staphylococcus aureus mupA conferring resistance to
                     mupirocin"
                     /gene_name="antibiotic-resistant isoleucyl-tRNA synthetase
                     (ileS)"
                     /tool="rgi"
                     /drug_class="mupirocin-like antibiotic"
                     /identity="97.4"
                     /coverage="8.4"
     Typing          2..954
                     /name="rep_cluster_910"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.895"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgtctcgta aaaatattaa aaatcaagca aatcaaaact tttatatgct acataaagca
       61 ttatttgtta atgaaaaata taaaaaatta agtgatagtg ccaaagttac ttatgcaatt
      121 ctcaacgata gagttagctt gtcgattaaa aataattggg tcgatgataa tggggatata
      181 tatttcattt ttacaaatga aagtctccag aatatattag ataaaagcaa gaatacaatt
      241 actaaaatta aaaaagaact tcaagcagta gggttacttg aacaaatacg tacaggattt
      301 aataaaccta ataaattata tttgcatgat atagaaacta atattaatgt agaaaaaagt
      361 attcaatcct catctataac ctataatgac aaggactccc aaattttggg actccagaat
      421 cccgaatttt gggactccag attctcaaaa tttgggagtc cagaatccca aattttagac
      481 cctaatgata ctgattataa tgatactgat tatattaaga ctgagaataa tgatacggat
      541 gatttgaatg ataataaact aacttttcct agtaatcata caaatcattc aaatcacgac
      601 aattcaaact ttaataatga ggctttaaaa tttcaattac tcgaagaact accgcaaagt
      661 attcaaaact atctaagtaa ctttgaagta gctgaaatta aaattatcaa aactgtatta
      721 ttaaaagcca aaacatcttt caacaatgcg attgatagct actacttgtt agaagatatg
      781 gaaatagaaa tacttcatgt tcttaaacgt ttcaaagcta tgcttattca aaaaaatgaa
      841 accgttgtat caatgcaagg atacttaatg aaatctctta agtctgaatt cgctgaaatg
      901 catacgctta ataaacgacg tgatcattta cccatcactt ctttatttaa ttaataatga
      961 tttatttaga gagcatcttt aaatagatgt tctctttttt tattaatcaa gtggttgcta
     1021 aagcaaccac ctagaccaaa cgaaaggtaa aggaggagat aacaaaataa catcaataca
     1081 atgtcacaat ttcacaacat agcatgctgc tattaaagaa aggaggaact cttatgcgta
     1141 ataagaaaaa gattaaggtt actttggcaa tgattaatgt tctgttaact gcagtcgaac
     1201 tttatcttca atggcaatta agtaaatctg aaaatgaact gtagttaagc aagtaggtgg
     1261 gactaaaaca gaaacgtttt agtcctattt ttttctataa acgagtattc ttcgtttaat
     1321 aatggctcaa acatgtcgca taaaatgaaa aacaaataat catttagtgt tgttttaact
     1381 tttaaaaatg taaaagtgtt aaccgtgttt atatttttta tcaatccttt gtagttataa
     1441 aagtgactta gtaaaatcgt ttttgctatt tattttgtta atgaacggaa ataaatggtc
     1501 gcatttatcg ttcaaaaaaa tcaaaatgtg gattcaatat aggtaaaaaa taagtcgtta
     1561 atgttcaaga aacggaccga ataaaatttt aaatttgaac ttttctatcc taaactaagt
     1621 aaagatattt acttagtttt ctcttttttt atctccaatc attttactaa caatactcat
     1681 tttgaaaata aaaataagaa cttaaagtaa aaaaatgaag aaaagaatag cctcttttgt
     1741 ctccaagtac gttttacttt tggaaatatt acaaaaagta gagtctgttt tcggagtctc
     1801 aagtatgagc ataaggaaat ccagtaccac ctttggtggt attcagcata gctgaaagat
     1861 ttacctttta ttcgttctgc tcaattattc accatatata gcttaaaagc tttatataaa
     1921 ggtgattata agcattctta ggcatttgac taaagagggt gatatcacat tttattgcag
     1981 actctttaca attgttacaa gaccactttt aattgtcaga atactctact taacgttgat
     2041 ttgacgggct ttaaaatttt ttagactctc gagagtctga tttttttgat atcgagactc
     2101 catagagtct gtttttttgg acttttttcg tataaaaaat aagaccactt aagtgtgatc
     2161 ttattttaat ttttaggttt gattgatcaa atattgatgt aacaaatgcg tccttttgta
     2221 cctcattttg tattttgttt tagctctttt tgaccatatt tctgtttaga tttggatgtt
     2281 tttataattt gtttttgaat aataaggcct aaataatttc ttattacttt tattttatgt
     2341 tcattataat gaatcattta gggatatgtt tgagatactt tattcaaaaa gtgatgagta
     2401 caaaaatatt tttatagcaa aaatgtaagt gtttaatata aaaaatatca caagaattta
     2461 tcaaacatga gtaagacatt tttcatttat ttatacttta taagcagtat gataaatcat
     2521 acaagtgacc aatacgcgct ttctaaaaat cataattcga cttaattatg tacgctaata
     2581 tgactttgat tatgactaag tagacttaat aataaaggta atttgttttt taatagataa
     2641 tacttttgac ataagttcac ttatcggaag tcatctgtaa ctcaattatt agaaatggta
     2701 taatacaaag gtcgtcgttc acttctgtgc tgtatttagc atggaaggag gtgacatcat
     2761 gttcagtaca ctatttgtaa ctattatagc tcctatcgta gtaggagtta tactcacatt
     2821 attttctcat tggctgaata atcgtgagaa gtaatttagc gacgacatat agctaataca
     2881 ccaaaagagc ccgataacta ttcgcagtag ttatcgggct cggtgtttat catgctagta
     2941 cactatttgt taaattcagt atatcaccaa gtgtagatga atgcaaaaat ataagaaaag
     3001 taagtgcaat tctataatta gaattattga ttttctttga tactataaaa ttgctaacat
     3061 taaggctaat tagttgaata caaagacaag atgggagtat taaatgaaaa aggttaaatc
     3121 atatttaaaa aacattcaaa acaacgaaga gtatcaaaaa gatatagaat ttcttgaaaa
     3181 gaaaagtaat ggaagggaag acaaaaaact tatattagat atatgctttt tatcgacaat
     3241 tcccttgatt tcaatttata ttacatattt tttaagtttt tccaatccat ttgcaatttt
     3301 tatattaata attatagctg tgccagtttc ttataaaatt gctaaaattc tattggatca
     3361 tatgtacaaa gatgaggata gatttctagc attatataga aactacgaaa agggaaaatt
     3421 attatttctt actttaccta tcattggact cgtatctata ataggaagtt catttctctt
     3481 cgattattta atatttaaac tgaataatac gtctgtagaa atattagggt ccactcctac
     3541 tgttgtatat catattatta tttgttttat tcagtctatg ttcacgacta tgtttttaat
     3601 aatatttatt tatactattt tggttcttat atatggaagg tttacaaaat aaatgactag
     3661 agtacgctct aaataaacaa aaatagtcct cttattaaaa taagaggact atttttgttt
     3721 aaaattattc aagaccattc gctttctaac atactcattt gccataaatt ataatattct
     3781 ccatttaatt ttctaaagtc tcttttttct ccttctttta taaatccaat ctttttgtaa
     3841 cttttaatag ctgatttatt aaaggcaaaa acacctaatt caattctgtg tagtcccaaa
     3901 tcttcaaaag cctttttcaa taatttcttt attattttag ggcctaatcc ttggccacgc
     3961 atttgcggat cacctactaa aactttactt aacgtggcgg aacaattttt aaaatctata
     4021 ttatttaaag caatatgacc tataattttt tttgaattat tttcttcaat gataacttta
     4081 taaattattt tactagaatt ttctttattt gtgtctttaa tatattcctt taattgttct
     4141 tcatctaggg gataattaaa atctgtacct gcccatttga ctaaaagttc aggagagttt
     4201 atccagttta ttaataaatc aaaatctttc tcctcaaaat attcaaactt aatcaataaa
     4261 ttactcctta aataataggt tattaactat aaaaattcag tgaatgttgc aatataaaca
     4321 accactacaa ttttttgata ctttcttcat caactttcta tcttaaattt tcgatttttt
     4381 ataaagcgtt ttgtattatc taaataactc tttacaattt actgattttt aagcttttgc
     4441 taatagattt atgcaacttt aatattataa gtaaatctat gcacttcatc attaaattta
     4501 aattctgccc aaattttata catccctttt ttaggaaaat gagcataaaa ggttgtagaa
     4561 tcaggtgatt ctgggtgaac atgaatataa tcagttaatt gctcatcaaa tataatcaca
     4621 tgtcctaaag ctcctaaata aggttgggga gttaattctg tattgaaagt taaagggaca
     4681 tgttcatctt ctttagcact tatagaattt aaagttacat gaactccttt gttaactttt
     4741 acccaatttt tatcagaatt taaagatgtt gtagaggtta ttttatctcc aatttgcagt
     4801 tcaataggat gaacggaata cacatggttt tttggtgtaa catcaacaaa agcctggtaa
     4861 gttcctggct ctaattgttg gttaattata aataaacctt catgcttttt ttgagggtgt
     4921 aggtggtaat atttctccat gtcattagat actaaaacga aatgcatttc tttttcatgc
     4981 atagtatcta ataatggggc attattaaat tcatcttcta acgtaatttc tatattacca
     5041 tctctatata caacatttgc tttaatttcg ggtttgtttg aatgatattc atgattatga
     5101 ttcatatttt tatcctcctt aatttttaat aagggcatat cattaaacga tatgcccaac
     5161 tatttaaatt atttaattac atcgtaacct tgatcttcaa tagcttcttt aaagtcgttg
     5221 aaagctactt gattttcatc aaattcaact tccacattcc cattcgccaa gcttacttct
     5281 gaagatgtta caccatctaa tccatttaat gctttttcaa ttgaatgctt gcaatggtca
     5341 cagctcatac cttctacatt aataacttcg ttagtcaatg ttgtcacctc ctttcaagaa
     5401 atataagatt cttataattt catacgtttt agacgtaaag cgtttgtgac aacacttaca
     5461 gaacttaaag ccattgctgc tcccgcaacc caaggtgcta gcagaccaat tgctgctata
     5521 gggatacctg caacattgta accaaacgcc caaaatagat tttggcgaat attacgaatt
     5581 gtagatttac ttgcttttat tgcttttgga attaataaaa ggtctcctcc taaaatagtt
     5641 atatcagcag cttcgattgc aacttctgta cctgtaccaa tggcaatacc aatatctgct
     5701 ttaactagtg ctggagcatc attgacacca tctccaacca tagctacttt tttaccttca
     5761 gattgaattt ctgctacttt agaagctttt tcttctggta aaacctctgc aataatcgtg
     5821 tctataccaa cttgttttgc tattgcttgt gcggtacgtt tgttatcacc agttaacata
     5881 gcaacttcaa tacctaattc atgaagtttt tgaatagctt gttgggcagt atctttaact
     5941 gtatcagcta cagcgacaac ccctctcaat tcgttatcta cgcttataag cattgcagtt
     6001 tttccttctt tttcaaattg agcgagattt gtttcagctt cattagtttg gattcctttt
     6061 tcactcatta gttttcgatt tccgacaaaa agttctttac catcaattgt tgcatttata
     6121 ccgcgccctg gtatagcttc aaaatggtct acttctaaaa attctaatga tttttcttta
     6181 gcataactta cgatagcttc agctagtggg tgttcagaac ctttttctgc actagctaac
     6241 aattgtaatg tttgatcatc tccactaaaa tcagtgactt caggtgtgcc atttgttata
     6301 gtgccagttt tatctaaaac aactgtatta atagcgtgtg taccttcaat gtgttctcca
     6361 cctttaaata gaatgccatt ttcagcagct tttccggtac ccaccattat agaagtaggc
     6421 gtagctaagc ctaacgcaca aggacaagcg ataactaata ctgctattgc agcaactaag
     6481 gctggttcaa attgtcccgg ctgaactaat gaaatccata taataaatgt gaaaatcgcg
     6541 atacctacaa cgataggtac aaaatatcca gaaataatat ctgctagtct ttgtattggc
     6601 gctttagaac cttgcgcttc ttcgacaact ttaacaatgg aggcaagagc tgtatcttta
     6661 ccaacttttg ttgcttcaac agtaattgct ccatttttat tcattgttga tcctataaca
     6721 ttatcatttt gcattttttc aacaggaata gattcacctg tcaacattga ctcgtcaatt
     6781 gaagtcatac ctttaattat tttgccatct actggtattt tttctcctgg tttgataact
     6841 aaatagtctc cttcttttac ctcacttaaa ggaaccatag tctcttcacc gttgcgtaat
     6901 atacgtgctt ctttagcttg taaattcaac aatttactta acgcatttgt tgtttgtgtt
     6961 ttagcacgtg cttctaaata ctttccgaaa agaattaaag taattaatac agcacttgtt
     7021 tcaaaatata ggtgtggctc ataatttgta ttaattaacc acttaatcga ttcataaata
     7081 ctataaaaga aggctgcgct tgtacctaaa gcgacaagaa catccatatt tgctgaccca
     7141 ttacgaaggt ttttataagc gcctacataa aattgccaac caataacaaa ttgaacaggc
     7201 gttgctaata caaattggaa ccacgggttc ataaatatat gtggtatttg aataccaaat
     7261 aaatgaacga acattgtcat taacaatgga gctgctaaaa cagctgaaac aactaattta
     7321 attaactgtc gttttaattg tttttctttt tgggaacttt tttctgatgc ttctttttta
     7381 ggttgtgcct cataccctag gtttttaata cgttgttgaa attcatctac agacgtcata
     7441 tcagggttgt attctacagt agcactttct gtggttaaat taactgtagc cttatttaca
     7501 cctgagattc gatttaaaac tttttcgatt ttattcgaac aagctgcaca cgtcattccc
     7561 attacatcga gatccacttt ttcggttaaa actccataac ctgttttttg aattgtattt
     7621 gcaatatctt ctaatgatgt aacattgggg ttatattcaa ttgtagcttt ctctgtagaa
     7681 ggatttacat tagcgttaac ttcatctaat ttatttagat ttttttctac tttattcgag
     7741 caagctgcac atgtcatgcc tgtgatacct aatgaggttt ttttaatatt ttcactcaat
     7801 tatttctttc ctcctatttt gaaaattgtt ttaatacaac catcaattct ttgatacttt
     7861 cttctccgtt gccattttta ataccttcac ttacacaatt agatatatgg tcttcagtta
     7921 ctataaaacc cacttgtttt agggctgatt gtattgctgt tatttgtact agtacatcta
     7981 tacaatatct atcttctgct atcattgatt gtaaaccgcg catttgtcct tctaatcttt
     8041 tgagtctatt gagcaatgcg tcattgtttt taacagtagt agtgttcaat ttcacccctc
     8101 ctcatatacc ctaacggggt atctcttgtt ggaatctata ttatacccct agtaggtata
     8161 agtcaataca aaagtttcat ataaaaaatt aatatttata gtttgtttta agaggtacac
     8221 ttgtataaaa tgtatgctaa aacttatatt aggagagata tatttggata aaaatataca
     8281 acttgagctt tacacaagac ctacatgctc tgattgccaa gaatcaaaaa ggtatttaaa
     8341 ctctcaagag attagttata gtcataaaga tgtaagtcaa aatttggact tagaagaaga
     8401 aatgaaaaaa atatcaggca accgaattgt tcccttattt gttttttata aaaaaatttt
     8461 tggggtaaaa aaaagttgtt taaatattac gtgggatttg aaaataacaa aaaagatata
     8521 ttaaatatat tggaataatt aaataaacag ccattattaa aaaataatgg ctgtttattt
     8581 aatgatgatg ttgactgtct tcttctttca cgatacaaaa caatttttca ctatgattat
     8641 tgttagaagt ttcagtctgt attgtgacat gttgaatatt ttgatgattg agttcatgtt
     8701 ctatacgttt aagtaaaaac tcattttcag taatggtcat tgtatcttct acaacaatat
     8761 gacaagataa cgcgtttaat ccgctagtta ctgaccaaac atgaaagtca tgaatatttt
     8821 taacttcttt gaatttttta atagttttaa taatgtcttt tgtatttata ttgcttggtg
     8881 ctccctccat taatacatga agacttgatt ttgttacata aaagccgcta cgtagtacta
     8941 aaattgctac aatcacactt gctaaaggat ccgcccaccc ccatctaaaa aatataatga
     9001 gaagggctgc tataactgca cctatagatc caagcatgtc gcttattaca tgcaaatatg
     9061 ctccacgcat atttaagttt tcttctacat cgctcccgcg cagcattatc caagccacaa
     9121 taatattaat aaacaagcct accaaggcga taattaacat gcctgtagaa gctacctcag
     9181 gggggttttt aaatctctca atagcttcat aaaaaatata gatagctatt aacatcaaag
     9241 taataccatt aagtacagct gctagtattt caaacctttt gtagccaaaa gttttatttg
     9301 tattagcttg cttcgctcct aaagtaaatg caattaaagc aatacctaaa gaaatagaat
     9361 cacttaacat atgaccagca tctgaaatta acgcaagact gttagtaaag aaaccaccta
     9421 acccttctac aatcatgtaa cttgtaataa taataaaact aattaataaa gtctttttgt
     9481 tcgcgccatg tgtatgatta tgattgtgat cgttttccat ttaatccctc ctctttttaa
     9541 tgatgaaaaa tattttctat aatttgaatt tttgttttta taactataga gttaaaaaat
     9601 ataaaatttc aattaatgtt ttgttactcg aagaaaatca tactaactta tgaatatatg
     9661 agcatatatt cataagttag tatgattttt atcctttgtc aatatagaaa tgctttgtat
     9721 tttgtatatt aaataaaaac cctactttgc tttggacagt agtgggattt ttgcatatga
     9781 taaaccacac ttcacttgct aaatattaac tatattataa ttaacaagtg ataatttctt
     9841 tttagagaaa ataatgtatt cacgccttta ggcgtgaata cattattttt ttttgaatag
     9901 tttagaaaag atagattgtt tttgttcatt tttttttgat gcttttggag taatgatatc
     9961 ttcttttgaa tctatattat cagtttctat ttttttggta ttacttaata tattttggct
    10021 atttaaattc aaagattgtt cttgttttaa tgcaattgtt aaatcgtcaa tttgtcgatt
    10081 cttttgtcga atttctgatt ctaaatgctc tatgtattta tcgatataac tgctatattg
    10141 gttatttaat gattctgttt tgtttgtcga tttttcatca aattttgtcg attcttttgt
    10201 cgttttttta tttaaaattg tttttagata atctattgta ttatcaggtt ctgttgcaaa
    10261 gtaaaaaata tagctaacca ctaatttatc atgtcagtgt tcgcttaact tgctagcatg
    10321 atgctaattt cgtggcatgg cgaaaatccg tagatctgaa gagacctgcg gttcttttta
    10381 tatagagcgt aaatacattc aatacctttt aaagtattct ttgctgtatt gatactttga
    10441 tactttgtct ttcttacttt aatatgacgg tgatcttgct caatgaggtt attcagatat
    10501 ttcgatgtac gatgacagtc aggtttaagt ttaaaagctt taattacttt agccattgct
    10561 accttcgttg aaggtgcctg atctgtaatt accttttgag gtttaccaaa ttgtttaatg
    10621 agacgtttga taaacgcata tgctgaatga ttatctcgtt gcttacgcaa ccaaatatct
    10681 aatgtatgtc cctctgcatc aatggcacga tataaatagc tccattttcc ttttattttg
    10741 atgtacgtct catcaatacg ccatttgtaa taagcttttt tatgcttttt cttccaaatt
    10801 tgatataaaa ttggggcata ttcttgaacc caacggtaga ccgttgaatg atgaacgttt
    10861 acaccacgtt cccttaatat ttcagatata tcacgataac tcaatgcata tcttagatag
    10921 tagccaacgg ctacagtgat aacatccttg ttaaattgtt tatatctgaa atagttcata
    10981 cagaagactc ctttttgtta aaattatact ataaattcaa ctttgcaaca gaaccaataa
    11041 tttgcaatat ttacctaagg atgtgttaaa agaaattgaa tttgaatttg gagatataat
    11101 gaattatgaa tctatagata aagctacaaa taatgcagat attatttata atcttgcagc
    11161 tttagtatca gtgccttatt catataaaaa tagtgaatca ttttttgatg ttaatataaa
    11221 aggtttgtta aatttattaa actctgtaaa taaaaaaggt accattgaga gagttataca
    11281 aatgtcttca agtgaagtat atggttctcc tcaatatact cctataaatg aagcccatcc
    11341 gttacagcca cagtcacctt acgctgcttc aaaagttgga gcagatgctt tagcaacatc
    11401 tttttataaa acatatggaa cacctgtaac aattgcacgc ccattcaata cttatggtcc
    11461 tagacagtca agaagagcta ttattcctac aattatttca caagcattac atagttctag
    11521 tttaagttta ggaaatattg attctttaag agactttaat tatatagacg atactacatc
    11581 aggactacta gcattattag aagagactac gaatcaaggt gccccaataa atattggaag
    11641 tggttattct tactcgataa aagatattat tgatatagtt tctaaattat tgaataaaaa
    11701 tctatatgta aatagagatg ataatagaat acgtccttct aaaagtgaag ttagtgaatt
    11761 attgtgtgac aacactacaa tttcaaaatt aacatcatgg aaaagtaatg ttagtttgga
    11821 gcaaggaatt caaaatacta tcgctttttt ttacaaaaaa gataaaaact tcatagaaaa
    11881 aagcaataac tattttatct agtgtttaga aagtaagaag gaggttgttt atgaaagcat
    11941 ttatattaaa ggtggaaagg gtgaacgatt acatccattg actaaaacaa tcccaaagcc
    12001 actagtcgaa gtcaatggta ttagtatatt agatagaatt ataaaatttt taaaagatgc
    12061 taatatatac gatatttata ttagcgtagg gtatttaagc tttcagatag aaaaacatat
    12121 aaaaaatata ggcaaacaga aattaatata tatattataa aggaggatat acctttagga
    12181 acagccggtc ctctatcttt attaaaaaac gtagatgatg atttaatagt tattaatggg
    12241 gatattttaa ctgatgtaaa tttcaaagat ttctatcagt tctataataa aaatgatagt
    12301 ttagtaacaa ttttaaccat acctttaaca acaagtattc cttttggtgt tttaactgtt
    12361 aatgaaaatc aaaatataac aatgatagaa gaaaaaccta aaataaaaaa ctatatcagt
    12421 ggtggatgct acatctttaa taaagaaata ataaaaaaag tacctaaaaa taaaaatctt
    12481 aaaatgactg attttttaga aaaattaatt aacgataata tttctatttc ttcttatgtt
    12541 cataatggag tttggataga cgcaggaact tgggaagatt taaaaaaagc taaatccata
    12601 tttttatagg aggatatatt atgtgggaca ttgaagtttc atcatcagat ataagtcaga
    12661 aagatattga aattgtatgt gaaactatga aatctaattg gttaagtatg ggaccaaaag
    12721 taaaagaatt tgaaagcatg tgggcaaaag aacttggtat aaattacata tctgctgtat
    12781 ctagtggaac tgcagcatta catttagctt gtttatgttg cgagttcact tatggagatg
    12841 aagttattgt ccccgcatta acatttgtag ctacagcaaa cgctgtaaaa tataccgggg
    12901 caactcctat aatatctgat atagaatcta aggataattt aatattgtca attgaagaaa
    12961 tacgaaaaaa tataacatcc aaaactaaag gaattattat cgttcattac gctggatata
    13021 catacaatat tgaagaaatt tctaaattag caaaagaata caatctatat ttaattgaag
    13081 atgctgcaca tgctattact agtagttaca acaataaatc tttaggtact tatggagatc
    13141 tagcttgttt tagtttttat cctaataaaa atataacaac aggtgaaggc ggagtaattg
    13201 ctactaacaa taaggatttt catgaaaaaa tccgttcttt aagaacacat ggtatgacta
    13261 cagagacatg gaatcgatat aattccagta tttctacata tgatgtaaat aacttaggtt
    13321 acaactatag aatggatgat ctacgtgctt ctttaggtat ttctcaattt aaaaatatga
    13381 aaagaaacaa aatacacaga aagaatttag taaacaaata tagagaatta ttgttgggtt
    13441 ataaagaaat aactattcca tttctaacaa ataatactga tagttctaat tatatttttg
    13501 ttatatttgt aaaaaatcct attttgaaag aaaaaatgat tactgatctt agaaatgaga
    13561 agatacagac tagtttccat tatactccct tacataaatt tagttattat aaatcaaaaa
    13621 acttattacc aattgtagag gaggtttcta aaggtttagt tacattaccc ttacataatc
    13681 gtttatctat caatgatgta aaaaagggtc tgcactatta ttagtaaaag tatacaggaa
    13741 tggagagagc aataatgaat cggctaaata caaattactt tgataacttt tatattgatt
    13801 ggcagaacaa tgaaatatca gaaaattatg ttgaattttg tcaaaagcaa attaataact
    13861 taagtcacat tgttccttca ttaaaaaaag agaaaagaaa aatcatcgat acttgttgtg
    13921 gctgtggttt tcattctaaa tttttgatag ataaaggtca tcatgttatt agctttgaca
    13981 aatctgagga aatgttgaac tttgcatata aaaaaaatgg cattttaggt aaaagacaat
    14041 ctttagatga agaattccca gaaaatcacg tcgacttaat tcttaattta aatacttcta
    14101 tcggatataa aaaaaatgat ttaaaaaatt tgttaagaaa tagttatacc tccttaaaaa
    14161 aaggtggtat tttaattata gatttgatga accccgcctt tttctataaa aattttgaag
    14221 aacaaatgat tttcaacttc aaagattacg aagttaatca aactattaaa ataaataaaa
    14281 tttataatag tatagtttca acatgggatg tttataaaaa taacgaatat agcaaagacc
    14341 tttcaagaga attaaaattt aaattatata ctactaatga tataatttgc agtagtttgt
    14401 attataactt tactttatcc aatatatctt tctatggaga catgaaagga aatgaatttc
    14461 atgaaaattc accaagacta atagtaaaaa taacgaaata agtgatactc taggaggctg
    14521 aaaagttttg acaaagaaat atttaaacac ccagaatgaa atattagcat tttggaatac
    14581 tcaaaagata tttaaaaaat caattgacaa tagaaaagga caggaaagtt ttgtttttta
    14641 tgacggcccc ccaactgcaa atggccttcc tcatactggc catgttcttg gaagagtaat
    14701 caaggattta gttgcaagat taaaaactat gcaaggtttt tatgtagaaa gaaaagcgag
    14761 gatgggatac ccatggctta ccagttgaat tagaggttga aaaaaaaatt ggaattaaag
    14821 gaaaacaaga cattgaaaag tatggaatag aaaattttat aaatgaatgt aaaaaaagtg
    14881 tatttaatta tgaaaaagaa tggcgggatt tttctaaaga tttaggatac tgggttgaca
    14941 tggactcccc ctatataact cttgagaata attatattga aagtgtatgg aatatattat
    15001 ctacattcca taaaaaagga ctattatata agggacataa ggtgactcct tattgtacac
    15061 atgatcaaac cgctttaagt tctcatgaag tagcgcaagg ctataaaaac gttaaagatt
    15121 tatcagctgt tgttaaattt caacttacaa atagtaaaga tacttatttc ttaagttgga
    15181 ctaccactcc ctggactttg cctcgcaaat gtagcattag ctataaataa agatcttaat
    15241 tattcaaaaa ttcgggtaga aaatgagtat tatatcttag ctacagatct aattaattct
    15301 ataataactg aaaaatacga aattattgat accttttcag gaagtaattt aattaattta
    15361 aaatacattc ctccttttga aagcgacggt ttagttaatg catattacgt tgttgatgga
    15421 gaatttgtta ctaactcaga aggaactggt attgttcata tagcaccggc tcatggggaa
    15481 gatgactacc aattggtttt agagcgtgat ttggatttct taaatgttat aacaagagaa
    15541 ggagtatata atgataggtt ccctgaatta gttggtaata aagctaaaaa tagtgatata
    15601 gaaatcataa aattattatc caaaaaacaa cttttatata aaaaacaaaa atatgagcat
    15661 aattatcctc attgttggag atgtggtaat cctttgatat attatgcgat ggaaggttgg
    15721 tttattaaaa caactaattt taagaatgaa attattaaca ataataataa tatagagtgg
    15781 tttccttctc atattaagga agggagaatg ggaaatttct tagaaaatat ggttgattgg
    15841 aacattggta gaaatagata ttggggaaca ccattaaatg tatggatttg caatgattgt
    15901 aatcacgaat acgcaccaag tagtattaag gatttacaaa ataattccat caataaaatt
    15961 gatgaagata ttgagttgca tagaccttat gttgataata tcactcttag ttgccctaag
    16021 tgtaatggga aaatgtctcg agtagaagaa gtaatcgatg tttggtttga tagcggctct
    16081 atgccgtttg ctcagcatca ttatcctttt gataaccaga aaatttttaa tcaacacttt
    16141 ccagctgatt ttattgcaga aggagttgat caaacgagag gctggtttta cagtttacta
    16201 gtaatttcta ctattctaaa aggaaaatct tcttataaac gtgctttatc tttaggacat
    16261 attctagaca gtaatggtaa gaaaatgtct aaaagtaaag gaaacgttat taatccaact
    16321 gaattaatta ataagtacgg agccgattct ttaagatggg ccttaatttc ggatagtgct
    16381 ccatggaata acaaaagatt ctcagaaaat atagtagctc agaccaaatc gaaatttata
    16441 gatacgcttg ataatattta taaattttat aatatgtata ataaaataga tcactataat
    16501 cctaataatg aaattacaaa aagtagaaat acattagata attgggctct ttctcgctta
    16561 aacaccttaa taaaagaaag taatatttat gtaaataatt acgatttcac ttccgcagcc
    16621 agattaatta acgaatatac caatacaata agtaattggt atattcggag atcgagagga
    16681 cgattttggg aacaaggaat ttctaacgat aaaaaagatg cgtacaatac gctttatgaa
    16741 attttaacaa ctttatcaag actagtggct ccatttgttc catttatatc tgaaaaaatc
    16801 cattataatt tgactggaaa aagtgtgcat ttacaagatt atccacaata taaagaaagt
    16861 tttattaatc aagcattgga agatgaaatg cataccgtta taaaaattgt agaattatct
    16921 agacaggctc gcaaaaatgc agatttaaaa attaagcaac ctttatcgaa aatggtgatt
    16981 aaacctaata gtcaattaaa cttaagtttt ttacctaatt actattcaat aataaaagac
    17041 gaattaaata taaaaaacat tgaattaact gataatatta atgactatat tacctatgag
    17101 cttaaattga atttttcttc tgtgggacca aaactaggga acaaaacgaa aaatattcaa
    17161 acattgatag actccctatc agagtatgat aaaaaaagtt taattgagtc taataacttc
    17221 aaaagtttat cttctgatgc tgagttaact aaggatgatt ttataattaa aaccttacct
    17281 aaggatagtt atcaactcag tgaagataat gactgcgtta tattattaga taaaaattta
    17341 tctcctgaat taattcgcga aggacatgct agagagctca ttagattaat tcaacaatta
    17401 agaaaaaaga aaaatttacc aataaatcaa cgtattgata tttatatcgg tgtaactggg
    17461 gaattattag aatcaataaa aaccaataaa aatatgttta aagaaaattt gctgattaaa
    17521 aatatacact taaatgttat agatgaatat gaaaatacta ttcattttaa taataaagaa
    17581 ataaaaattt ccttattata ttaaacaaac atggccactc tattttagta gagtggccat
    17641 gagttatcaa agccaagcaa aaggtgataa actatgtata attttgatta ttctaaatta
    17701 ccaattaaaa atattcaaaa aatatttcct attgcagggg gatatgtgaa tctatctttt
    17761 tcagttgatg cttccaacaa aaaatatttt ttaaagctac aacctaatac taaatcaaat
    17821 ttttttgatt atgagttatc cagtttaaaa gaattaactg ataaaaatat tcctgttcct
    17881 caaattatta ataaaggaga attagacaat aattcttttt tactgttaga gttcattgaa
    17941 aatggccatg cttatcctga aagctataga aaactaggta aaatagttgc aaacatgcat
    18001 aaaaatataa attcactaaa tctatttggc tttagtcata atttcaatgg aggaacgatt
    18061 gaattcacta ataaatggac ttcttcttgg ggggatttat ttattaaaag taggatggat
    18121 aagctatgtt ctgaaatata caagaaacgt ttattttcaa tttcggatct tttattatat
    18181 gaagatatac gaaaaattat gttgaagagc ttatattatc accaatcgtc accatcatta
    18241 cttcatggtg atctttggaa aggaaatatt ctttttcaaa aaaatggaga tcctattcta
    18301 tgtgatccag tctgtttata tggagataga gaatttgata ttggatatac tctagcatta
    18361 gaaaaatttc cattagattt ttatcaagaa tataataata tatatccgtt gtgtgttgga
    18421 tatgaaaagc gaatagaatt ttacaagtta tatgtgttta tgattcattt atttgctata
    18481 ggtacagatt tttatgataa agttaaagat accatgtata atattttaaa taattacggg
    18541 gttgatttta taaaaggata gggtgttgac tttgtttcaa ttttctaaaa tcatttatct
    18601 acttctaata gtcacttttt tcgaacgatt ttcacatttc ctcataatac cttttttatc
    18661 tatttattta attcaggaat tttcatattc tagtttagag atagggatta ttttatcttc
    18721 ttccgggtgt acagcattaa tcatcagttt tatattagct ccgatgttaa gtacagtaaa
    18781 taagaagaaa attatactat gtagtatttt tacagctttt atcagctttg taatatttcc
    18841 atacatacat agttattatg gttttttatt ctttactata attaatacta tagcaagtag
    18901 tttactctct cctacatata aaaccttatt aactttatac tctgaaacat caagaaaacg
    18961 attagtattt aatataaggt actatctcat aaacatagct gctgcattag gaccttttat
    19021 ttctatacaa attcaagaag tatcttcttt aaaaaatgta tgcatcttta tttcttttat
    19081 ctactttatt aattttatct tttttctttt ttcttctata gaagaaaaaa gaagcgaaaa
    19141 tcctaaatta aactatctta cctcttttgg tattatcaaa agaaataaag cttatgtatt
    19201 attgctttta ggaagtatat tctttgtatt tggttattct caaattctaa gttctatacc
    19261 tcaattcttt gccataaaat cgcactctaa agctacttct atttatggtt acttactgtc
    19321 tataaatggt gtgatagctt taacttgtca atactttatt tatttattaa acaagcgata
    19381 ttctcataaa tcatgcatta tattaggagc aattacttta actttaggat tatttacttt
    19441 tggcttaaca gaaaatattg tattacttgc ttttgctata attgtattca ctatggggga
    19501 aatgttagta tttactacta tagatattag aatagacgaa attaccgata agtataataa
    19561 aggagcttat tactctttgt taggtttaca aaacatcggt tcattattag ctccagtaat
    19621 tggtggttta attattactc aatttaaatc tggaatgtta atttttagca tcctttcttt
    19681 aattacatct ttcagcattg tattatttta taaaagtaat aaaataaaaa tataattgct
    19741 gtatattttt tgaattcccc ccctaaagtt gaaccttaaa actcaacttt agtgggggaa
    19801 ttattttgat gaaaaagcct aaaaaagcct attgtaaacg gcgtattaat gagacatata
    19861 tcaaaatcaa aggaaaatgg tgctatctgt atcaatcgca cgatacagac tgtcacacat
    19921 taggacttat ttttaaaaag tcgttatggg aaatttgatg attccatatt tctattgtat
    19981 aatcatcttt ttctacaact tgacacatta catattgaca acctatcttt ttcaaagctg
    20041 tatacctatg tgcactatct aacacaagat aacctctatt gtactttgta acgataatag
    20101 ggtttctttg tttttcctct ctaataactt tatatttcaa aaaatctccc cagttaatta
    20161 aaataattat atcagttttt tattccaatt gttttattga cgttgagcct cggaaccctt
    20221 aacaaaccca aaacttgtcg aacggttggc ttaatagctc acgttatgcc gacattcgtc
    20281 tacaagttta gttaagggtt cttctcaacg cacaataaat tttctctgca taaatgtgtg
    20341 gtctactttt tgtctttcga aggtttccaa aacaaaacca caactataaa aaataagaag
    20401 taaataataa accaaaaatc taaatggctt tgatttattt gttgatgtat aaaaacaagc
    20461 atcaaaatag ataataatag ttggacaaca atacaagatg atatctaaaa acactccttt
    20521 ttttaatgat tctcttcttt atttttatct tttattttag caaataaatt tgttgtctct
    20581 tcttcaaaaa ctgttgctaa agggactaag atatttaaca agcatacaaa aattccaaaa
    20641 catatagagt tccttttcaa caaactttat cacaagtcct attaaaattt taaatacctt
    20701 atttgttatt taaagatact tttagaacat ttaggcgtat tttatgtata tttaattcaa
    20761 aatcatttaa aggatctgag aacacaaata tgagctaatt aaaaaaacaa gtctaaactt
    20821 ttttgatgaa ccagagacaa atttttgaga tgcttatcag ttacatgtaa attaaaattt
    20881 ggcataaaat catttaaaaa ccaactttgt tttttagttt tttcggagac atttttcttt
    20941 taaaacacca aaattttgat ttgaacccaa atcatgaatt aagagcataa gagaaatttg
    21001 ccatctttta caaaggtagg tctggcgaag ccagacattt caaaggtttc agagtttttc
    21061 ttttggtgcc taaattttgt gtttgtaccc aaaatgtacc cctacatatt gtatctgtac
    21121 ccattttgta cccatacttt ttttcgactt ttcaataaca aatgctagct tttttagcta
    21181 aagttcccta ttttttaaga gataattttg ttttcgaagt gcccaattgc tgtaattgaa
    21241 tgtgtttttt tctttatcat tttttgaatt aaattaccat attcagtgtt atctaaattt
    21301 aaaagtttat gtttttattt aagtaattac accgaaactt aatatacatt tttgatataa
    21361 aattcatttt aagtcattaa taagttctgc attttttcag aggttcttgt taaataatcg
    21421 aacgaaataa tggaatattt tgattaattt tttcagaatt tatgcgtcat ttttccatat
    21481 gttagacaag ggtaaaaaca aaagtagagc gcacatttat gataagaaat tttaataatg
    21541 ttgtgagtat acttaactaa attttaagat gaatatcgta tggtatgagc gatttagtcg
    21601 acaattttat aagtttgaaa attgttaaga gcttcaaaga tcaacgttaa tacattaatt
    21661 tcaattctaa ttctgtactt attttacagt taataaattg agtattatta agctaataat
    21721 aattattacg agattgatta agtttataaa aatcttaaag attttcttgt cattgtattc
    21781 tggactttta tatagaagca tgtcacacat aaacaaattt gttgtaaaca ttccgaatat
    21841 tgaagctaag attccaaaat gaatctccat aaaaatagtt tgaataaaaa ataagagaat
    21901 gaaattatta aaaataataa gatttcataa attaacagaa tcatgatttt tctcctataa
    21961 attaaagtta aagaaaacat aaatcatcat caattttcta atgttcaaag cgaaaattat
    22021 taggaaagct gttaaatgaa atgacgcaaa tttaagagta tataggatca agtaaaagca
    22081 tattagattt taaaaggtgc taaaaagtat tattggaaag taagtataaa atcaataatt
    22141 ctattaaaaa tgcaatagtc attagtaaac tagtaaattt atttacttat agtgatgtgt
    22201 ttaattacta taataaactt gaaatatact tataaagtat ctcttttgcc tctagatatc
    22261 atagaaatgg atctgaatct cactatcatt acataaaatg acttatcgga agttatctat
    22321 catcgtatat gcggagatga tataatatgt aggtcgccta tctctcaggc gtcaattcag
    22381 acgcagagag gaggtgctaa tctatgctag aaatccttgt tcacatcacg accacagtca
    22441 tcagtggttg tattattgcg ttatttacgc attggctacg taatcgcaat aataaatagg
    22501 cgactatagc cacacctaaa aatcccctca ctattgccgt agtgagggga ttggtgcatc
    22561 tatgctagtt tccttgttaa ctaaattata acactggtta gtagagaaat gcaaaactat
    22621 atatatatac tactactact ttattaattt ttttagtttt tttgtgaatt tttccaaatc
    22681 atcaatatat tccttcaatt gttcggggct cggtgtttct tcgcctaggg cagatgacct
    22741 atcatgaacc cattttgaag attctgtcat acctttttca acttcttcat ataattctct
    22801 attaaatgga gcttttttta gtctagacgt ttgaattgct ggattaaatc tttcgataga
    22861 tccatttaat aataattctt ctatactttt ttcccaagtt tcccttaatt cttcacacca
    22921 catttttgcc ttataactat attctaactg ttcttccgga gcatcagaag agatattgtt
    22981 ataataagtt gtgatatttt gaagttgttc ttttagataa ccaattcttc ttttaacagt
    23041 catacttatc caaggatgtg agtttgtaga aatacctgtt tcatttttaa tttttctaag
    23101 tgtattatga cgacaatcaa gttgtttttc tgaagactta ttttgcatta atagtaaaaa
    23161 aggtaggtca tgagtgaaaa ttactacttg cttttgttgt gcttcatcaa ttaatcgatc
    23221 agcaattatt tcttttcttt tgtgatcaag agaagaaaca gggtcgtcaa atacaataca
    23281 aacattattt ttgttcattg aggtttcaga caaaaaattt gctaaagcaa tagcccgttg
    23341 ttctccctcg ctcagtatgt ctattggttt cttttcttgt atggttaact tatttaaggt
    23401 tgtacctttt ctcccccttt gtttgatttc agctgaaaag ttagcattta atttttgaca
    23461 ttcattattg aatgtctcaa tatatgtgtc agttacgtat ttagaaaata aactgttttg
    23521 ttttgaagtg atagaacgtg tgttaatttt tattttgcta gcattatcta cccactcttt
    23581 gttgtttata aagtcttcta ttttaggaag taatttttcc acttttaatt tatcattaaa
    23641 ttcattctct ttaatttgta gttcttcaat ttcctttttt acactgtctt catcaaggtc
    23701 ttcaatcaaa ttatttaaat tgtttataac tttttcaatt tcattataat caaaattgta
    23761 acctttaatt tgtgaatccc attgtaaatt attgagagct ttaaggacct tatctttgag
    23821 actttcaaaa ttatttgaag cttgattaat agaattaaat aaatctatat tgtcatcttt
    23881 tagaaagtag cttaatatag aatctttatt taaaatagtt gtatttataa gtttaaagcg
    23941 tctttcttcc ttcttgatag aattattttt aacggctaat attttttcgg actcgttttt
    24001 taaatatttc caatatttat ctattagttt tatattacta atatcttggt gacaaaaaat
    24061 acagtaatta acactatgat ttatagttgt ataatattta taggctgatt ctataaaatc
    24121 tttccattct tttgaaccta atttttctat gttttcatct ttaaattgag ctatcccttc
    24181 agttaaagat acgtctttgt aatgatttct ctcttctatc aaacctttaa cttcacttaa
    24241 ataagcagaa ctaaaaagtg ggttgagttt ttttattgtt tttttaacat cttcaagaat
    24301 tgatattaaa ttttggtact cttgtttttt atcaaatatt tgcattgatt gtaattctga
    24361 tattcgctta ttattattag catgattttc catatcattt tcagttaatt ttacttttat
    24421 ttttaattca tcaaaatcat cctttgtatt taaatttagt aacaatcttt tgatagaagt
    24481 ttctttatca aaatggttta taaatgtatt gtctaaggtt ttatcattga ttttagcttc
    24541 aaatttttct tttaattttt gaacaatttc taataattta tcaaaaaatt taaattctgt
    24601 tggtgaaaat gatagttcag attcttgggt taaatcatgt aaagcactat gtgaatcaaa
    24661 taccgataca tggtctgtat aaggatggtt cgaatctttt ggataatata gtttatctat
    24721 attaccatca ttagtttcaa agttaatatt agctgaagga ggcgacggat tatccttgaa
    24781 tatattggaa agtaatctag tatctcctct tgaaataaaa atattattaa gtaaacgagt
    24841 aaaccctgat ttaccactac cattttcacc atagattagt gttaactgag gaccaataac
    24901 taaattagca ttatctttaa tggcatttac accaataaca ttatctaaac ctttccaatt
    24961 tgctatttta tgttcatcag tagtattagt aatatttcgg aattctattt tttctctatt
    25021 aaaatttcca tgttcaaggt tgttatattt cataaatata gaaaaaaaat cttctatatc
    25081 ttcatcataa atgtgactct tgtctagtat ttttttagct ataacttgtt gccagtaagg
    25141 ttgctcttca atccatttta ctatatcatc aataatcact tttcattctc cttttataaa
    25201 aatatagatt gcaactttat tatactaata ctttaaaagt agaagatata tttttattat
    25261 tttattgtgt atatattatc aaaaaaatta ggctgataaa ggtacaccct aatcatacaa
    25321 agagagttat tgaatttata ataacttaaa cgtatgatta gggtgtatat taattgtgga
    25381 gtgaaaatga atgattatag gttatgcaag agtatcttcg gtagatcaga atttagagag
    25441 acagctagat aatttgaaaa catttggcgt agagaaaata tttacagaga aacaatcggg
    25501 aaagtcagta gaaaatagac ccgtatttca agaagcactt aactttgtga gaatgggcga
    25561 tagatttgta gtagaatcga ttgatcgctt aggtcgtaat tatgatgaag tgattaacac
    25621 agttaattat ttaaaggata aagaagttca attgatgatt actagtttac ctatgatgaa
    25681 tgaagtgatt ggtaatccac tattagataa atttatgaaa gatttaatcg ttcaaatctt
    25741 agcaatggtt tcagaacaag aacgaaatga aagtaaacgt agacaagcac aaggtattca
    25801 agttgcgaaa gaaaaaggtg tgtataaagg acgcccttta ctatattcac ctaatgctaa
    25861 agatcctcaa aaacgtatta tctaccatcg tgttgttgaa atgttagaag aaggcaaagc
    25921 aattagtaag attgcgaaag aggttaatat cacaagacag acagtttata gaattaaaaa
    25981 tggtaaggga ttatcttgat aaatggattg ttaatgcaaa tgagatcttc tcacagcgtc
    26041 ctaaattata tgttattcat ctattatgag attctgataa taagacaaga aaagagagtg
    26101 cgaattcgca ctctcctttt gtgtagtact attgaaattt tgtcttaaaa acgaacgtaa
    26161 tttagaaata atatttattg gtatttcaag aatatatata taattattta ctaagtccat
    26221 ttaaaaaaat ttgagagaac ttgttcataa gtttaattct ttcattaata ttttgttcat
    26281 gtgtaaaggt aacaattcca ttaacagcgt ttgctgctat tttactaaca gcattaacat
    26341 cattaataca ccattcgcca tttaaattac cctccttaaa aattacatga taagcatcta
    26401 tatatttgtt ttctaattta ttcatttttt cattaatgct attagtttta taatattcag
    26461 tgcaaaattc aattattgcg ttttgaagtg gataatagta ttcggttgtt aaagatagtt
    26521 cattatataa ataaaatttt tctctattag ttttacattt gatttgttcc tttttccact
    26581 gttcttgcca tttagattct tctatattta aaatttctaa aaatagattt tcttttgttt
    26641 taaagtgata ataaagattc cctttactac tttctgataa tttaacaatt tctccagtag
    26701 tagtggcatt atatccattt tttataaata attcctttgc gacacctagt attttatctt
    26761 tcaagttcat cacgccttta atgagtatta agtactatca atgatagcac aaaaaattca
    26821 aagaataatt gtataacaca atacagccat ttaaatttcg caagattttt tgttgtaata
    26881 tgtaaaaaaa tagattacaa tccttataga ccgatcgcac ggtctataag gattggaggg
    26941 aacttaaatg atttcatttt ttacaaaaac tactgatatg atgacatcaa aaaaaagatg
    27001 gactgcacta gtagtattag ctgttagttt gtttgttgtt acaatggata tgacaatatt
    27061 aattatggct ttaccggaat tagtaagaga gttagagcct tctggtaccc aacagttatg
    27121 gatagttgat atatactctc ttgttttagc tggctttata attccattga gtgcctttgc
    27181 tgataaatgg ggaagaaaaa aagcattatt aactggattt gctttatttg gcctcgtttc
    27241 attagctata tttttcgcag aaagtgcaga gttcgtaata gctattcgat ttttacttgg
    27301 tattgcaggt gctttaataa tgccaactac tctttcaatg ataagagtaa tttttgaaaa
    27361 ccctaaagaa agggccactg cattagctgt atggtcaatc gcttcatcga taggtgctgt
    27421 ttttggacca attatcggag gagctttact tgagcaattt tcatggcact cggcattttt
    27481 aattaatgta ccgtttgcga taatagcagt tgtagcaggt ttatttttat taccagagtc
    27541 taagttatca aaagaaaagt ctcactcgtg ggatattcct tctacaattt tatcaattgc
    27601 aggcatgatt ggactggtat ggagtatcaa agaattttca aaagaaggac tagcagatat
    27661 tattccatgg gttgtaatag tattagcaat taccatgata gtgatatttg ttaaacgtaa
    27721 tttatcaagt tctgatccaa tgttagacgt aagacttttt aaaaagagat cattttcagc
    27781 tggtacaatt gctgcattta tgacaatgtt tgcaatggca tctgttttgt tattagcttc
    27841 acaatggtta caggttgtgg aagaactttc tccttttaaa gctggcttat acctattacc
    27901 tatggcaata ggagatatgg tgtttgcacc aattgcaccc ggattagcgg cgcgatttgg
    27961 accgaaaata gtgttacctt ccggaattgg aattgcagcc attggcatgt ttattatgta
    28021 tttctttggt catccattat catattctac aatggcttta gcattaattt tagttggagc
    28081 tggtatggct tcactagcag ttgcatctgc tctaataatg ttagaaacac ctacatcaaa
    28141 agcaggtaat gcagctgctg ttgaagagtc tatgtatgac cttggaaatg tttttggtgt
    28201 agcagtactt ggtagcctat cttctatgct ttatcgtgta tttttagata tttcatcttt
    28261 ttcatcaaaa ggtatagttg gagatttagc tcatgtagct gaagaatctg tagtgggcgc
    28321 tgtcgaagta gctaaagcta cggggataaa acagcttgca aacgaggctg taacatcatt
    28381 taatgatgct tttgtagcaa ctgctttagt aggtgggatt atcatgatta tcatttcaat
    28441 agttgtctat ttgttaattc ccaaatcact tgatataact aaacaaaaat agtactaaac
    28501 atatattttt agatattgta gattagttta tttttaaaat tagtaatagt taaaaagtag
    28561 aaccattaat tttaaatggt tctacttttt tattattaag taaaattata aaagacaatt
    28621 tcttaaatta ataatatgat atacctatat ctaataattt attagtatta ataaaccttg
    28681 aaaggatgat taactgatga atagagcaga tatttttaaa atatttgatg tagaacttaa
    28741 tataactata tttttaggag cactagtagc aactttcatc tattttataa gttacatgaa
    28801 caatgtaaat gaattaatta cattatgctt aacattagct tttcctgcat atttattaaa
    28861 aattagcaga tcgttcgagg ttattttatt agaggaaaaa ataaaaaata gtaaaatcaa
    28921 aatctgtgac aaagatagaa ttgaacgaga gatactggtg aaaaagaacc taatagatga
    28981 actattgttt cctaatagag ttattaaaaa atatacactg acaattttaa tttacagtat
    29041 aggtattatt attcttttac tactttgtaa tatgttaagt tatggaattg gtgaaaatgt
    29101 caattttatc tggagattac tagcttgtta tgtaacgagt gtcacagtga ttatagttgc
    29161 cttgattata atgataatga tatttgatct tataattgga ttactattaa attttcaaat
    29221 atttttaaaa aataaaaagt atgatgactt tttataatta ttcgatttat ataatgaaaa
    29281 attaaatgat taaacataga aacctcaaaa caaaccatat ttaatagagt ttatggcgcc
    29341 ttatacaaat aaaggctatg ctgttaaaga attatgtagc tatcttcaga ttaatatgga
    29401 tgatgtttat actattggcg atagaaaatt gatttaccta tgtttaatac cctagataat
    29461 tcttctgata atttagtttt tgttagagtt taacataact gatgattatc agaagttcca
    29521 tcactataaa aggtgtatca agggtttata aactcttgat acacctttta tagtcatttt
    29581 taattaccaa acagtttact ccaaaaactt tttttagaat gattttcgtt tctgatatcc
    29641 tctttctgct caccatctat tttattacct tgttgcagtt cactatcttg ttgcttatcc
    29701 tcatgtttat ctttactttc atccctaaaa tgggaaacca ttttttcttt ttgactatct
    29761 gagtcattat ttatagaatc catattttcc attgtttctt gaacttcaat gtcctgcctc
    29821 ttattagcag aataattgag ttgcctttct tcttctaact cagactccaa cctttgtatt
    29881 tttttgttac tttctaatgc taatacttgt tggttttcaa gtaatttcga cctttcttgt
    29941 aattcttttc tataaaattc tattgtcgtt tcatgacgtt tttcttgttt ttcaagttgt
    30001 ttatttaaag tatctatttg cttttcgagt agttcaatta tttgaacatc atatttagat
    30061 tcgttttttt tattatctgt tttaactttc tctgaactta cattagcact ttcaaagcca
    30121 tatttctttt tatttctgat tactctttga atgatttttt ctacatcaac atcattttta
    30181 atgaatgaag tattatcctg tttcactgtt tctatattca atctttttat attattaaat
    30241 acagtctgtt tactaacttc caattcttca cttatttctt taacgctctt catatcttca
    30301 accctttata aatactttat caacccttta taaataaatt ttatcataaa tacttttata
    30361 aagggatctt aagtattctt aaaaaacctt ttataaacat ttgataataa tcttatcaag
    30421 tgtttataaa aggtttttag tgggattata atatctttta tatgttcttt tttaatgata
    30481 taatgtccat aatacgtttt agtcccaact actggtaata gttgggactg ggtaataaaa
    30541 cgttacaata cgttagctat ttaatttgat atatgtatta tatacaacaa tatctacagt
    30601 ttgcaagtca aaaagttatg tggatttgta atgttttatt acctctattc aaatttaatt
    30661 ggaaagaggt tttttatt
//
