LOCUS       NZ_CP093175            18220 bp    DNA     circular CON 20-JUL-2023
DEFINITION  Staphylococcus epidermidis strain TMDU-137 plasmid p2, complete
            sequence.
ACCESSION   NZ_CP093175
VERSION     NZ_CP093175.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN26515364
            Assembly: GCF_024204745.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus epidermidis
  ORGANISM  Staphylococcus epidermidis
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 18220)
  AUTHORS   Saito,R., Ayibieke,A. and Yamada,K.
  TITLE     bloodstream S. epidermidis isolates from two Hospitals in Tokyo
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 18220)
  AUTHORS   Saito,R., Ayibieke,A. and Yamada,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-MAR-2022) Molecular Microbiology, Tokyo Medical and
            Dental University, 1-5-45 yushima, Bunkyo-ku, Tokyo 113-8510, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Unicycler hybrid assembley v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 249.0x
            Sequencing Technology             :: Illumina MiSeq; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 07/20/2023 03:41:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,479
            CDSs (total)                      :: 2,395
            Genes (coding)                    :: 2,333
            CDSs (with protein)               :: 2,333
            Genes (RNA)                       :: 84
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 37 of 62
            Pseudo Genes (incomplete)         :: 33 of 62
            Pseudo Genes (internal stop)      :: 22 of 62
            Pseudo Genes (multiple problems)  :: 24 of 62
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP093175.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..18220
                     /organism="Staphylococcus epidermidis"
                     /mol_type="genomic DNA"
                     /strain="TMDU-137"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1282"
                     /plasmid="p2"
                     /geo_loc_name="Japan"
                     /lat_lon="35.701735 N 139.7642509 E"
                     /collection_date="2015-03-09"
                     /collected_by="TMDU hospital staff"
     gene            complement(84..452)
                     /locus_tag="MNU44_RS12190"
                     /old_locus_tag="MNU44_12180"
     CDS             complement(84..452)
                     /locus_tag="MNU44_RS12190"
                     /old_locus_tag="MNU44_12180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002503834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="WP_002494366.1"
                     /translation="MKKILKILITSIIVIIITLTVWTFSVITYQEHKSEKIIDHVIERK
                     GWDKKIKNEKMSFNIMMGYAEKDIAFKDQPYSEYEYNVTPAPAPWTDDKEYKVWGETDL
                     QKKDSYYKYLLESEPYRK"
                     /name="DUF3139 domain-containing protein"
     gene            556..951
                     /locus_tag="MNU44_RS12195"
                     /old_locus_tag="MNU44_12185"
     CDS             556..951
                     /locus_tag="MNU44_RS12195"
                     /old_locus_tag="MNU44_12185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002502726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="WP_002494367.1"
                     /translation="MKRKYKITGIIFIVLLIVLTLIFSIVHHYANVQKHEEAKLKQKVH
                     HIFKQKGWEDKVKEEKNIFTFNTGDNDLQVTFKDEPYNTYTYSIDEDNKVYGNAVLKDE
                     YDKDFDSKKKYKEYLRKMHFEEKYDLK"
                     /name="DUF3139 domain-containing protein"
     gene            1563..2012
                     /locus_tag="MNU44_RS12200"
                     /old_locus_tag="MNU44_12190"
     CDS             1563..2012
                     /locus_tag="MNU44_RS12200"
                     /old_locus_tag="MNU44_12190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002494368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002494368.1"
                     /translation="MKKLLSVFIASLLVLTGLSFSSINQGNTASAKTKYKTTITYKGQK
                     YVYVGHYKHHFSKKEVKKVVKFSKGVHSGNKLVSAASKLSKNGYVKASSAIYKAFDFGL
                     KNELKGSYFYTAAKKGTGVTISYDMYTATTGPNHTIAKNFKHSYN"
                     /name="hypothetical protein"
     gene            complement(2172..2558)
                     /locus_tag="MNU44_RS12205"
                     /old_locus_tag="MNU44_12195"
     CDS             complement(2172..2558)
                     /locus_tag="MNU44_RS12205"
                     /old_locus_tag="MNU44_12195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002494369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002494369.1"
                     /translation="MKKAIFSIIISLILVLTVTGCSNSSKEKPIKKSALEINPTSKAVN
                     ITINKKENNKPEKIGKVYRYKNNNAKEITNDGIKKDTKDTLIWKGVANKYDNVKDLLGE
                     SILYEVKYKNGDIKKFERKIKYTE"
                     /name="hypothetical protein"
     gene            complement(2578..2739)
                     /locus_tag="MNU44_RS12210"
                     /old_locus_tag="MNU44_12200"
     CDS             complement(2578..2739)
                     /locus_tag="MNU44_RS12210"
                     /old_locus_tag="MNU44_12200"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_162153024.1"
                     /translation="MNEREQRQKLNITLPPKLITNLDKVKTKYGINKSKQIENLISKYL
                     NEEYGNLE"
                     /name="hypothetical protein"
     gene            3588..3962
                     /locus_tag="MNU44_RS12215"
                     /old_locus_tag="MNU44_12205"
     CDS             3588..3962
                     /locus_tag="MNU44_RS12215"
                     /old_locus_tag="MNU44_12205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002467994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002494371.1"
                     /translation="MKKIVYILGTIIVLGFCYFYVNLIFFDSWTRYSAEKEINNYISNH
                     DTKKLKEISANNKTYQLLKHAKHVTIKGDTDNQGGGHIGYFTSTINGKEGALFVHLNFG
                     LFPEIPKVTKLEVFDKNIYE"
                     /name="hypothetical protein"
     gene            complement(4553..4972)
                     /locus_tag="MNU44_RS12220"
                     /old_locus_tag="MNU44_12210"
     CDS             complement(4553..4972)
                     /locus_tag="MNU44_RS12220"
                     /old_locus_tag="MNU44_12210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002494373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070858627.1"
                     /translation="MLKLYYKFNFATEPDLAYIRSMNVTEYIRQTAVGNRIKPTVIEYP
                     KEQITMDDSNSKNNTNNLYKVIEHLEEDNEALKSDRDALRQRHDQLEDDIEQYKRENEI
                     FHRLLEHFDSTAFMNFNTYRDDRPLKKEIKRLKEH"
                     /name="hypothetical protein"
     gene            4988..5662
                     /locus_tag="MNU44_RS12225"
                     /old_locus_tag="MNU44_12215"
     CDS             4988..5662
                     /locus_tag="MNU44_RS12225"
                     /old_locus_tag="MNU44_12215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_225088350.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKIVTDQAPSTKAAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVKKTRYQNINTAKSTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            complement(6422..>6718)
                     /locus_tag="MNU44_RS12230"
                     /old_locus_tag="MNU44_12220"
                     /pseudo=""
     CDS             complement(6422..>6718)
                     /locus_tag="MNU44_RS12230"
                     /old_locus_tag="MNU44_12220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001568503.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(6735..7706)
                     /locus_tag="MNU44_RS12235"
                     /old_locus_tag="MNU44_12225"
     CDS             complement(6735..7706)
                     /locus_tag="MNU44_RS12235"
                     /old_locus_tag="MNU44_12225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_049391782.1"
                     /translation="MSNFNIKEIQKEKFYQLPKVFFTNPKYTKLSNDAKITWSILRDRL
                     DLSIRNNWVDENGDIFFIYTNEKLKSILNISSPNKLSKIKKELTEADLFNQIRVGLNKP
                     NKLYIKKPEVTEADVYYISQQENDIEQHNNTDVSLSYVQKYDNDTSRNINMIHHDISKE
                     YTNDTDLSNTDYIETENNDTYDMNDTYNNQTNHNHSDHTNHQQSEFNNDALKFQVLEEL
                     PQQIKDYLSNFEIKEIRIIKSVLLKGKKSFNNTFNTYYRLEDVEFELVSVLKRFKAMLL
                     QKNETVEAMQGYLMKSIKAELEEIHTLNMRRQNMKKHNIFNQ"
                     /name="replication initiator protein A"
     gene            8200..8880
                     /locus_tag="MNU44_RS12240"
                     /old_locus_tag="MNU44_12230"
     CDS             8200..8880
                     /locus_tag="MNU44_RS12240"
                     /old_locus_tag="MNU44_12230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_002503026.1"
                     /translation="MKSMKEIADELNVTKMTVYNNAKKANVKFQKIDNVNYLTSEDEII
                     VINRIRKNQNKNDDFESEKKEEPNNDNLVKDETIKQLYNQIDIYKEQSNRDKEQINTLN
                     RLLENQQVLALESNKKIKKLEDQLEEERRLNYSFDTSVNERQNVNVQEATFTGESKDTD
                     QQQEWEQPTEVQHKDIPEEKENENLNEEPSTIDDKQFEEIDNEYEDKEEKPPKKGFWSR
                     LFGN"
                     /name="DUF536 domain-containing protein"
     gene            complement(9000..9399)
                     /locus_tag="MNU44_RS12245"
                     /old_locus_tag="MNU44_12235"
                     /pseudo=""
     CDS             complement(9000..9399)
                     /locus_tag="MNU44_RS12245"
                     /old_locus_tag="MNU44_12235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002499214.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /name="VOC family protein"
     gene            9394..10524
                     /locus_tag="MNU44_RS12250"
                     /old_locus_tag="MNU44_12240"
     CDS             9394..10524
                     /locus_tag="MNU44_RS12250"
                     /old_locus_tag="MNU44_12240"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002456255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="WP_002456255.1"
                     /translation="MQSKKIFDYVIPLAEDGFEVNSELEMSIKKYSKGIDKSSPFFKGD
                     GNTVKNGDIVKQPQLTKTLKGIKNNGPNYFYDKLAKHLTTELNGQIDKTDFNNYKSKQK
                     KPSETKYLNTHVYSSSNPLGGGLMLQGLKLDEMLNNGQSDEQYLNSVLSGRDLMYSNRD
                     IVNAKTNFSQEYLSNMYISNKYNNQNTSDSISDNSVKKTSTLHFVVVDKQGQMTSTTNT
                     LSGYFGSGKYMDEGFYMNNSMTNFSDNKDSNNYHAKNTVPRSYISPTIIVGPDYYMGIG
                     SPGGNKIPTILNEVIIDYLRGNGSLQDSIYKPRFYNDGNTVHFEKGMNKKYLDILQNQG
                     YNIKEEKDNPNFGSVQAGIYHIKNKKTEIANDVGTR"
                     /name="gamma-glutamyltransferase"
     gene            10773..11630
                     /locus_tag="MNU44_RS12255"
                     /old_locus_tag="MNU44_12245"
     CDS             10773..11630
                     /locus_tag="MNU44_RS12255"
                     /old_locus_tag="MNU44_12245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002499202.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="WP_000162894.1"
                     /translation="MTKKMVIISFGRILLIIIGALITAYGLESILIPNNVSDGGVTGIS
                     IVGSTLFGLPLGILIGIINLPFIWLGYKQIGRKFAIFSIIGILSLSIFTSIMHHVPTII
                     EGDSLLITVVGGVVIGLGMGLALRNGGALDGIDMLAVLLSRKLPFGTSDLILFLNTFVF
                     ILVSTVFGFKGAILSALAYFIASKVIHIIEEGLSGSKTFKIITKDYDIMNKEIKERLGR
                     YCTFTKVTIDEENNSFVEISCVINKLEEQKLKEIINDVDPDAFIAIYDTAEVKAGNMKK
                     SDIY"
                     /name="YitT family protein"
     gene            complement(11780..12391)
                     /locus_tag="MNU44_RS12260"
                     /old_locus_tag="MNU44_12250"
     CDS             complement(11780..12391)
                     /locus_tag="MNU44_RS12260"
                     /old_locus_tag="MNU44_12250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002487382.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000635275.1"
                     /translation="MIVGYARVSSVDQNLERQLENLKTFGAEKIFTEKQSGQSIENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEVINTVNYLKEKEVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDNDDLF"
                     /name="recombinase family protein"
     gene            complement(12845..12940)
                     /locus_tag="MNU44_RS12265"
                     /old_locus_tag="MNU44_12255"
     CDS             complement(12845..12940)
                     /locus_tag="MNU44_RS12265"
                     /old_locus_tag="MNU44_12255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_011276848.1"
                     /translation="MLEILVHITTTVISGCIIALFTHWLRNRKDK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            <13892..14151
                     /locus_tag="MNU44_RS12270"
                     /old_locus_tag="MNU44_12260"
                     /pseudo=""
     CDS             <13892..14151
                     /locus_tag="MNU44_RS12270"
                     /old_locus_tag="MNU44_12260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001568503.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            14806..15189
                     /locus_tag="MNU44_RS12275"
                     /old_locus_tag="MNU44_12265"
     CDS             14806..15189
                     /locus_tag="MNU44_RS12275"
                     /old_locus_tag="MNU44_12265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="WP_002485672.1"
                     /translation="MKLYVNEIIRTNNFEDDDMMNKILGMWDSFYKNNDDYKGEVYAVY
                     HDYESDYKGDYSLALCTEDISADKFFEVDFADSTEYKCSGKDEIINVWKRIWGDEEENK
                     IQRSYYIDCEEYKKDGSVVIHLF"
                     /name="effector binding domain-containing protein"
     gene            15635..16493
                     /locus_tag="MNU44_RS12280"
                     /old_locus_tag="MNU44_12270"
                     /pseudo=""
     CDS             15635..16493
                     /locus_tag="MNU44_RS12280"
                     /old_locus_tag="MNU44_12270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440631.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /name="RepB family plasmid replication initiator protein"
     gene            complement(16541..17152)
                     /locus_tag="MNU44_RS12285"
                     /old_locus_tag="MNU44_12275"
     CDS             complement(16541..17152)
                     /locus_tag="MNU44_RS12285"
                     /old_locus_tag="MNU44_12275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_032603908.1"
                     /translation="MNKSKVAEIRKQKSLTQENLAEKAYVTVRTIQRMEAGEEVSSETL
                     KSVSNALDVTVNELFESISSSDKEEEIMEISKEQQKQFNYRKSELFTIKLITFSFIFVF
                     LGLFGIFVGELNGLEQNIYGIIWLFTLFLILAIMHYFLNVFISKKLDKKYPMTIGMKNR
                     VSNRKSEPVKNGWDFMARYWWIVFPIGGFLSWLIPELTGK"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(17384..17479)
                     /locus_tag="MNU44_RS12290"
                     /old_locus_tag="MNU44_12280"
     CDS             complement(17384..17479)
                     /locus_tag="MNU44_RS12290"
                     /old_locus_tag="MNU44_12280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002501808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_002501808.1"
                     /translation="MLAIFVYITVSIFIECCVALFKFWLEQRNKK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(17809..18174)
                     /locus_tag="MNU44_RS12295"
                     /old_locus_tag="MNU44_12285"
     CDS             complement(17809..18174)
                     /locus_tag="MNU44_RS12295"
                     /old_locus_tag="MNU44_12285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020368092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002494365.1"
                     /translation="MKWLKIIILILSLVPIEFIGLFTDYQTGLLIGYIPFIIVAILISR
                     SIFKFGLKNNISIIISRCIGTFLSWECVHWFMNIYDSSDYFKPLTTDIFALFLGAIHFI
                     VIMLIYLVIYGFSHRNN"
                     /name="hypothetical protein"
     Typing          complement(6736..7706)
                     /name="rep_cluster_1110"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.32"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          15636..16377
                     /name="rep_cluster_1442"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="88.575"
                     /coverage="86.0"
                     /evalue="0.0"
ORIGIN
        1 attaatataa ttaggtaaaa gtctacgctg tctttaagtg atagatgaat gatctctatt
       61 ttttattatg ttatacattt atattatttt ctgtaaggtt ctgattctaa aagatattta
      121 taataggagt ctttcttttg taaatctgtt tccccccata ccttatattc tttatcatct
      181 gtccatggtg ctggtgctgg tgtcacgtta tactcatact cactatatgg ttgatcttta
      241 aaagcaatat ctttttcagc atatcccatc ataatattaa aactcatttt ttcatttttt
      301 atttttttat cccaaccctt acgttctata acgtgatcga tgattttctc actcttgtgt
      361 tcctgataag taatcacact aaaagtccaa actgttaagg taataatgat aacaataata
      421 gaagttatta atatttttaa gattttcttc atttttgtat aattcctctt ttttaataat
      481 ttttatgata aatatgtatt attgtattta attttacaaa atattaatta aataaatttg
      541 cttaaggata ctaatatgaa aagaaaatat aaaattacag gtatcatctt tatcgttctt
      601 cttatcgttt taacattaat ttttagtata gtgcaccatt atgctaatgt tcaaaaacat
      661 gaagaagcta aactaaaaca aaaagttcac catattttca aacaaaaagg ttgggaagat
      721 aaagttaaag aagaaaaaaa tatatttacg ttcaatactg gagataatga tttacaagtc
      781 acttttaaag atgagcctta taatacgtat acatattcta ttgatgaaga caataaagta
      841 tatggaaatg ctgttttgaa agatgaatat gataaagatt ttgatagtaa aaaaaagtac
      901 aaagaatatt taagaaaaat gcattttgaa gaaaaatatg atctgaaata aaaaagcaag
      961 cgactacgat aattgatagt cgcttgcttt ttagtgttct ttcaatttgt ttaatgcttt
     1021 tttatgattc gttttctatc ttgtaatttg gaggcttata tatgccattt taaaagcata
     1081 tgcgcgtctt taatatgaaa tatactaaaa ttacctatat gatattaaat gaaaagcctg
     1141 tataaagttt aaaatagctt agaaagcaaa aaggagtatt agcattgaaa tcaattgttc
     1201 attttatttg cctctttatc atattttgta tttttggata tgtgatagat ttaatatttt
     1261 ttaaagaaat aaatattttt ctgattttag aatcagcctt tattttatca ttactaatca
     1321 tgccgatatt aaagattgta aaagagatag aaattgaaaa atagaactgg taaataccat
     1381 tttctatact taatgtttaa taaaaatagg ctactaaaat tcagttaata aagatccatc
     1441 tttattaact gaattttaaa aaaatatata tagtgttaat ttttttaatt aaagtagtta
     1501 taacttaatt tatatgataa agtcatattt aaacatataa atattttaca ggaggtcttt
     1561 ttatgaaaaa gttactttca gtttttattg caagtttatt agttttaacc ggattatctt
     1621 tttcttcaat taatcaaggt aatactgcga gtgctaaaac aaaatataaa acaactataa
     1681 cttacaaagg tcaaaaatat gtatatgttg gtcattataa acaccatttt tctaaaaaag
     1741 aagttaaaaa agtagttaaa ttttctaaag gagttcattc aggaaacaaa ttagtatctg
     1801 ctgctagtaa acttagtaaa aatggttatg ttaaagcatc ctcggctatt tataaagcct
     1861 ttgattttgg attgaaaaat gaattaaaag gtagctattt ttacacagca gctaaaaaag
     1921 gtacaggcgt aacaatttct tatgatatgt atactgcaac aacaggtccg aaccatacta
     1981 tagctaagaa ttttaaacat agttataatt aaataaatgt gaggggaagg attaatcctt
     2041 cccctcacat ttattttcaa gcttttttga acggttgaat tttagaccat aatttatgaa
     2101 ttcatagata ttagataata tttcagctat tattcttaaa atattttcca ttatcatcac
     2161 tactttcaat tttattcagt atatttaatt tttctctcga atttttttat atccccattt
     2221 ttatatttaa cttcataaag aatactttct cctaataaat cttttacatt gtcgtatttg
     2281 tttgctacac ctttccaaat caatgtatct ttagtatctt ttttaatacc gtcattagta
     2341 atttcttttg cattgttatt tttatatcga tacactttcc caattttttc aggtttgtta
     2401 ttttcttttt tatttattgt aatattaaca gctttacttg taggattaat ttctaatgca
     2461 ctttttttaa ttggtttttc tttagaacta ttactacatc cagtaacagt tagaactaaa
     2521 ataagagaaa taataatact aaatattgct tttttcattc taatcatcct tttttgctta
     2581 ttcaagatta ccatattctt catttaaata ttttgatatt aaattttcaa tttgtttaga
     2641 tttattaata ccatattttg ttttaacttt atctaaatta gttattaatt taggaggaag
     2701 agtaatattt aacttttgtc tttgttctct ttcattcaaa cccacaacac tctcctttta
     2761 tttatgcgta taaagtagca ttacatgcgt acaaagtcaa gtttgtaccc ataaaagaag
     2821 tatagtatag tttgtttttt actttatgga gctattataa ttacgacaaa cgataaaaga
     2881 aaaacaattt tttcctctca aaaaagccct atagttttca actaagaata aatgagcaaa
     2941 gcaaatggta agatagtcct tcagctatgc tgaatactac cttaagcggt aatggatttc
     3001 cttatgctct ttaaaataca aaagttacat tatataccta ctttttcagg ttttagcttt
     3061 tttctaagaa gaacaattga gataaaaaat atattttcct ttctgaaagt gttgagaaag
     3121 aaattttaaa atgatttata gcctatctgt tgaacaaaaa agtttttagt cattttttaa
     3181 taaaatgttc tagaaagggc ttaaaatgca aaataaaaag actactcaaa aaatgagtag
     3241 tctgaagaat agtttttgat gtattaaatg aaagggagta ctacattaat catatcacac
     3301 gcatttatac cgagaaaatt tattgatgtt gagaagaacc cttaactaaa cttgaagccg
     3361 aatgtcggca tagcgtaagc tattaagccg acgattcgat aagtttaggg attgttaaag
     3421 attcggaggt tcaacgtcaa taaagcaatt taaaactata gttaaaatag ggttctgttg
     3481 caaagtcaga aagataagta tataacctta tgtttctgac tttgcaacag aaccacttta
     3541 atttaccata aaaacttaaa tattttgagg agataaggag tctttaaatg aaaaaaatag
     3601 tttatatact tggtactatt atagttttag gcttttgtta tttttatgta aatttaattt
     3661 tttttgatag ttggacacgt tattctgctg aaaaagaaat aaataattat atttcaaatc
     3721 atgatacaaa gaaactaaaa gaaatatccg cgaataataa aacatatcaa cttttgaaac
     3781 atgctaaaca tgtgacaata aaaggagata cagataatca aggtggaggt catatagggt
     3841 attttactag tacgattaat ggtaaagaag gagcgctttt tgtacatctt aattttggtt
     3901 tgtttcctga aattcctaaa gtaaccaagt tggaagtttt tgataaaaat atttatgagt
     3961 agcataattg ctactcattt ttcgtgttag ttattctggt tctgttgcaa agttagaaaa
     4021 atatagctaa ttacgtccat atagcattaa gcttctatgc tatgataatc gttagaaatc
     4081 tggctaagaa tctggagtgt ttttatgatt tttttaagag aaaaaatagt catgaaatat
     4141 acaaaaaaat catgtatatt ttgttaaata gtacagtgat agcatttata ttattgctaa
     4201 ttgtgaaatt aatatttgat ttcctttttt agactatatt catatttttt cagatttgta
     4261 tttttattgg ggttaattat tggtagtatc ccagatttta tagaaaagaa aggttaattt
     4321 tatgttatta aaaaataaga tttattcagg cattattatt gttattttta tagtttgttt
     4381 gattatagga ttgaatgaaa atatcattgg aaatccttta ggagaaaaaa tattttattt
     4441 attaggtttt ctattttttg tattattaat tattggtaca acaaaaaata gaaagcatta
     4501 atgtcttctt tttgccccat ttcttacgat aaacattttt tgagtagcct ttttaatgtt
     4561 ctttcaatcg tttaatttct ttttttaatg gtctatcatc acgatacgta ttaaaattca
     4621 taaatgcagt actatcaaag tgctctaaca agcgatgaaa tatctcattc tcccttttgt
     4681 attgttctat atcatcttca agttggtcat gacgttgtcg aagtgcgtct ctgtctgatt
     4741 tgagtgcttc gttgtcttct tctagatgtt caataacttt atacaaatta ttcgtattat
     4801 tcttagaatt agaatcatcc atcgttattt gctcttttgg atattcaatc accgtcggtt
     4861 taatccgatt acccacagct gtttggcgta tatattctgt gacattcata ctacgtatgt
     4921 aggctaaatc tggttctgtt gcaaagttga atttataata taattttaac aaaaaggagt
     4981 cttctgtatg aactatttca gatataaaca atttaacaag gatgttatca ctgtagccgt
     5041 tggctactat ctaagatatg cattgagcta tcgtgatata tctgaaatat taagagaacg
     5101 tggtgtaaac gttcatcatt caacgatcta ccgttgggtt caagaatatg ccccaatttt
     5161 atatcaaatt tggaagaaaa agcataaaaa agcttattac aaatggcgta ttgatgaaac
     5221 gtatatcaaa ataaaaggaa aatggagcta tttatatcgt gccattgata cagagggaca
     5281 tacattagat atttggttgc gtaagcaacg agataatcat tcagcatatg cgtttatcaa
     5341 acgtctcatt aaacaatttg gtaagcctca aaagatagtt acagatcagg caccttcaac
     5401 gaaggcagca atggctaaag taattaaagc ttttaaactt aaacctgact gtcattgtac
     5461 atcgaaatat ctgaataacc tcattgagca agatcaccgt catattaaag taaaaaagac
     5521 aagatatcaa aatatcaata cggcaaaaag tactttaaaa ggtattgaat gtatttacgc
     5581 tctatataaa aagaaccgta ggtctcttca gatctacgga ttttctccat gccacgaaat
     5641 tagcatcatg ctagcaagtt aaacgaacac tgacatgata tattagtgat tagctatatt
     5701 ttttactttg caacagaacc attcaaatct tagatagaaa tattaaattt aaacatggga
     5761 atagttcact tacagtaact aaaaaactcg ttaaaattat aataatgaat atatgtatga
     5821 agtcaaaaaa tgaagtaaat taagtaatta ttcgcctaac ttttttaaca ttttttaagg
     5881 aatcattgaa aataataacg tcgttctatc aatatttttc ttcgactcgg ttattaaatc
     5941 gagtcttttt ttgtttttat tttctttgtc tttcgtatta aatcgatctg gaaattcata
     6001 aagttaacct aattattgtt gttatattct tctcgttaaa tcgtcttttc aggtatgaac
     6061 tcgctgtatc tatggtgtat aatgaaacta taacaaattc aagagcataa gaggaatcct
     6121 gcacagaaat gtctccaaat gtctccattc agtagccatt tctgtgcaaa atattgattt
     6181 gacagtgtca aatgggattc ctatttatgc gataaaaatt gttatatgac tcccgaacgg
     6241 ctacacaaaa gctaccgaat agctacccaa aatcaaaaat gtctcccaaa tggataccaa
     6301 aaataaaaaa tgtataccaa atggagacat aaatttgtct ccatttggta tacattcggt
     6361 ctccatatgg tatatatttt tctgaaattc ttacaaagaa tattattata tttagacagc
     6421 attacaaatt ttttaagaag taattttgct tttcgaaatt ccaaattgcc gtaattgaat
     6481 gagctttttg ttcttcttct gtcgtttttt cttcatcact tgtttgaatt aagttaccat
     6541 cttcggcatc atctaaattc aaaagtttat gttttttctt aagcaataca ccataactca
     6601 acatgcgttt tctgtataaa ccttgctcta aatcattaac aatctctgca tctttttcac
     6661 ggtctcctgt taaataatca gaggacttaa ccgaatactt tgatgtctct ttgattgcta
     6721 taagattatc taaattattg gttaaagata ttatgttttt tcatgttttg acgacgcata
     6781 ttaagtgtgt gtatttcttc aagttcagct ttaatcgatt tcattaaata tccttgcata
     6841 gcttcaacgg tttcattctt ttgtagcagc atggctttaa aacgttttaa aacactgaca
     6901 agttcaaatt cgacatcttc taaacgataa tatgtattaa atgtgttgtt aaaagatttt
     6961 ttccctttga gtaaaacact tttaataata cgaatttctt taatttcaaa attacttaag
     7021 taatctttga tttgttgtgg caattcttcg agtacttgga atttaagtgc atcattatta
     7081 aattcggatt gttggtgatt tgtatgatcc gaatgattat ggtttgtttg attgttatat
     7141 gtatcattca tatcatacgt atcattattc tcagtctcta tataatcagt attacttaaa
     7201 tcagtatcat tagtgtattc ttttgatatg tcatgatgta tcatattaat atttcttgac
     7261 gtatcattat catatttctg gacgtatgat aatgatacgt ccgtgttatt atgctgttct
     7321 atatcgtttt cttgttgtga aatataatat acatcagctt ctgttacttc tggtttttta
     7381 atatataact tattaggttt attcaaacct actctaattt gattaaataa atcagcttct
     7441 gttaattctt tttttatttt agatagctta tttggactac taatatttaa aatagactta
     7501 agcttttcat tggtataaat aaaaaatata tctccatttt catctaccca attatttctt
     7561 atagataaat ctaaacgatc tcttagtatt gaccaagtta tttttgcatc attagatagt
     7621 ttagtatatt taggattcgt aaaaaaaact ttaggtaatt gataaaattt ctctttttgg
     7681 atttctttaa tattaaagtt ggacatacaa aaaacctctt tcatatttaa atttctaaaa
     7741 gaggtaataa aaaagctata agtaagttta tatgtattcg acttgcacta ataattctta
     7801 gtatatataa taaaaatata acaactatat aaacaaacaa actacttgtt ttattaccga
     7861 agaaacctga ctattcccgt agttaggttt cttttatata tttatattaa cacttttaaa
     7921 agttttgtta aattgtttat atacatttgg gtgtatgcac tttcaaagaa agataaatct
     7981 ttgtataaat tattttatat gggtatatcg tataacaccg tataaacgct tatatagcaa
     8041 gtataaaggg tgtataagtg ttatataatt gggttgaaac cttatacgta tagttatata
     8101 tggatatgtg tataaagaat tatataacct tgtaataaca aatataatgg ctgtataatg
     8161 atataaacgt tatgtatata actatatgga gggcgttata tgaagagtat gaaagaaatt
     8221 gctgatgaat taaacgtaac aaaaatgact gtttataata atgctaaaaa agcaaatgtg
     8281 aaatttcaaa aaatcgataa cgtaaattac ttaaccagtg aagatgaaat tatagtaata
     8341 aaccgaataa gaaaaaatca aaataagaat gatgattttg aaagcgaaaa aaaagaagaa
     8401 cctaataatg ataacctggt gaaagatgag acaataaaac aattatataa ccagatagat
     8461 atatataaag aacaatcaaa tagagataaa gagcaaataa atacacttaa tagactttta
     8521 gagaatcaac aagtattagc attagaaagt aataaaaaga ttaaaaaatt agaagatcaa
     8581 ttagaggaag aaagacgact taattattct tttgatacgt ctgttaatga gagacaaaat
     8641 gttaatgtac aagaagcaac atttactgga gagtctaaag atactgatca acaacaagaa
     8701 tgggaacagc ctacagaggt gcagcataaa gatatacctg aagagaaaga gaatgaaaac
     8761 ctcaatgaag aaccatccac aatagacgat aaacaattcg aagaaataga taatgaatac
     8821 gaagataagg aagaaaaacc acctaaaaaa ggtttctgga gtcggttgtt tggtaattaa
     8881 cacaataaaa agcactacaa gctcatgaac ttgtagtgct tttttatgct agaacttctg
     8941 ataatcatcg attatgtaaa ttatgattaa aaaaagagca tatgatatat gctctttttt
     9001 taattttttc ttttggtaaa gagatgataa gcaattccga attcatcttt aacatatccg
     9061 taaccttccg tgtaaaattt cggagcctaa ttcaacgaat ttatcataaa ttctctttgt
     9121 gtcttcgaca ttttcgaatg tcacacacaa agaaacatta tttcctttag taattggaag
     9181 tccttcagta tcatctgcaa tcattaattt cacatcacca aataaaataa cacattgatc
     9241 aattttttct aaatctcttt catcaacatc tttacgcgct tctaatggtc tatcttttat
     9301 tctttgtata taaactgtat ttgcattaaa taattcttct aagcgtattc ttaatttttc
     9361 tgcattatta gtgattaaaa aatatgggtt ctgttgcaaa gtaaaaaaat atttgattat
     9421 gttattcctt tagcagaaga cggttttgaa gttaattctg aattagaaat gagtataaaa
     9481 aaatatagca aaggtattga taaatcatct ccttttttca aaggagatgg taatactgtt
     9541 aaaaatggag atattgtaaa gcagccacaa cttactaaaa cattaaaagg cattaaaaat
     9601 aatgggccta attactttta cgataaactt gcaaagcatc taactacaga attaaacggc
     9661 cagattgata aaactgattt taataattat aaatcaaaac agaaaaaacc aagtgaaaca
     9721 aagtatttaa atacccatgt ttattcatca tctaatccct taggtggcgg attaatgcta
     9781 caaggtttaa aattagatga gatgcttaat aatggtcaaa gtgatgaaca atacttaaat
     9841 agtgttttat caggaagaga tttaatgtac agtaatagag atatcgttaa tgctaaaacg
     9901 aacttctctc aagaatacct ttcaaatatg tatataagta ataaatataa caatcaaaat
     9961 acatctgact ctattagcga taatagtgtt aagaaaacga gtactttaca ctttgtagtc
    10021 gttgacaaac aaggtcaaat gacgagtacg acaaatacac tatcaggata ctttgggtct
    10081 ggtaaatata tggatgaagg attctatatg aataattcca tgacgaactt ctctgataat
    10141 aaagatagta acaattatca tgctaaaaat actgtgccaa ggtcatatat atctccaaca
    10201 attatagttg gaccagacta ctatatggga attggtagcc ctggtggaaa taaaatacca
    10261 actattctta atgaagtaat tattgattac cttagaggta atggatcgtt gcaagatagt
    10321 atatataaac ctagatttta taatgatggt aatacagtac attttgaaaa agggatgaat
    10381 aaaaagtatt tagatatact tcaaaatcaa ggttacaata ttaaagaaga aaaagataat
    10441 cctaattttg gaagtgttca agcaggtatt tatcatatta aaaataaaaa aactgaaatt
    10501 gcaaatgatg taggaaccag ataaactgat ttaaaataca ccaatcttca aaattttaga
    10561 gattggtgta ttttaatata tttgtaaatg ccttgggaaa tttttcattt atttactttg
    10621 agtattagac gctgattaaa cattaaatta tcttttttag aattttgttt aaaaaaatat
    10681 gatatcaatc attaacacca atttcattaa attgataaaa caagttataa tataggtgaa
    10741 gactttttaa taataaaaat aggagttcaa aaatgacaaa aaaaatggtg attatatcat
    10801 tcggcaggat tttacttatt ataattgggg cacttattac agcatatggt ttggaatcta
    10861 tattaatccc aaataacgtt tctgacggag gagtcacagg gattagtatt gtaggttcca
    10921 ctttgtttgg tttaccttta ggaatattaa taggaataat caatttacca tttatatggt
    10981 taggttataa acaaatcgga cgtaagtttg ctatattttc aataataggt atcttatcat
    11041 tatctatatt cacttcgatt atgcatcatg taccaacaat tattgaaggt gattcactac
    11101 ttattactgt agttggtgga gttgttattg gattaggcat gggtcttgcc cttagaaatg
    11161 gtggggcatt agatggtata gatatgttag ccgttttatt atctagaaag ttacctttcg
    11221 gaacaagtga tttaatttta tttctcaata cattcgtatt tatacttgtt tctactgttt
    11281 ttggctttaa aggtgccatt ttatcagcgc tcgcatattt tattgcttca aaagttatac
    11341 atattattga agaaggacta agtggttcga aaacgtttaa aattattaca aaagattatg
    11401 acattatgaa taaagaaatt aaagaaagac tgggaaggta ttgcacattt acaaaagtga
    11461 ctattgatga agaaaataat tcatttgtag aaatttcttg tgttattaat aaactcgaag
    11521 aacaaaaact taaagaaatt ataaatgatg tagacccaga cgcatttatc gcaatatatg
    11581 atacagcaga agttaaggct ggaaatatga aaaaatcaga tatatattaa aattacgata
    11641 aataaaaagc taccagttat taggtagctt tttattggtt ctctcttttc ttgttttaat
    11701 attaaaatct cagaataatt gatcaccata agttttcaga cgctgtgaga agctctcatt
    11761 tgcattgaaa aaccgtttat taaaacaaat catcgttatc gtgtttaatt ctataaacag
    11821 tttgtcttgt aatattcact tctttcgcaa ttttactaat cgctttgcct tcctctaaca
    11881 tttctacaac acgatgatag ataacacgtt tttgaggatc tttcgcattg ggagaatata
    11941 ataaaggtcg tcctttatat acgcctttct ctttcgcaac ttgaatccct tgagcttgtc
    12001 gacgtttact ttcatttctt tcttgttctg aaaccattgc taatatctgt ataattaaat
    12061 ctttcataaa tttatctaat aatggattac caatgacttc attcatcatt ggtagactgg
    12121 taatcatcaa ttgtacttct ttctctttaa gataattaac ggtattaatg acttcatcat
    12181 aattacgacc taaacgatca attgattcca cgacaaaacg atctcccatt ctcacaaagt
    12241 tcaatgcttc ttgaaagacg ggtctgtttt ctatagattg acctgattgt ttttctgtaa
    12301 aaattttttc agcaccaaat gtttttaaat tttcaagttg tctttctaaa ttttgatcta
    12361 ctgatgatac ccgcgcatag cccacaatca tttagtttca cctcataatt aatatacacc
    12421 ctaatcatac attttaattg ctgtaatttc aacaattcat tttgtatgat tagggtgtac
    12481 ttatgattaa catttttaca ttatcttttc actaaatata aatagaaaag agcagaaaaa
    12541 ataaatataa tcataaatat tgtactagct aataaagcac ctgttgcttg ttcattataa
    12601 agtcctttta ttatatatag tatagctgta aaagaaaaag tgatgatcat taaagcaaag
    12661 aaaaaaactg ttagaaatcc tataaaactt tctattttat ttcatcctcc tatatagata
    12721 ctaattttgc attcctctac actatgatgt tataatgcac ttaacaagga atccagcatg
    12781 gatacaccaa tcccctcact accgtaaata gtgaggggat ttttgtaggt gtggctattg
    12841 tcgcctattt gtctttgcga ttacgcagcc aatgcgtaaa taacgcaata atacaaccac
    12901 tgatgactgt ggtcgtgatg tgaacaagga tttccaacat gaataacacc tcctccctac
    12961 gtcaaattga cgcctgagag ataggcgact ccattattat accatctgta tcttttgaag
    13021 catatgtact tccgataagt cattttatgt aatgatagtg agatccagaa ccatttctat
    13081 gatatctaga ggcaaaagag atactttata agtatatttc aagtttatta tagtaattaa
    13141 atacatcact ataagtaaat aaatttacta gtttactaat gactattgca tttgtaatag
    13201 aattattgat tttatactta ctttccaata atacttttta gcacctttta aagtctaata
    13261 tgcttttcct tgatcctata tactcttaaa tttgcgtcat ttcatttaac agatttccta
    13321 ataattttcg ctttgaacat taaaaaattg attatgattt atgttttctt taatttatag
    13381 gagaaaaatc atgattctgt taatttatga aatcttatta ttttttataa tttcattctc
    13441 atatttttta ttcaaactat ttttatggag attcattttg gaatcttagc ttcaatattc
    13501 ggaatgttta cagcaaattt gtttatatat tacatgcttc tatataaaag tctagaatac
    13561 aatgacaaga aaatctctaa gacttttata aacttaatta atctcataat aagtattatt
    13621 agcctaataa tactcatttt attaactgta aaatgagtac agaattagaa ttgaaattaa
    13681 tgtattaaca ttgatttttg aaactcttaa caattcccaa acttgtagaa ttgtcgactt
    13741 catcgctcac actatacgcc attcgtctta aaatttagtt agagagcctc acaacattat
    13801 taaaatttct tagcataaat gtgtgctcta cttttgtttt tacgcttgtc taacatatga
    13861 aaaaacggcg cataaatcct acaaaaacta atcaaaatat tccattattt cgctcgatta
    13921 tttaacaaga ccccctgaaa aaatgcagaa attgttaatg acttagaatg aattttatat
    13981 cgaaaacgta tactaagttt cgatgtaatt acttaaataa aaacataaac ttttaaattt
    14041 agataacgct gaagatggta atttaattca aacaattgat aaagaaaaaa cacattcaat
    14101 tacagcaatt ggacacttcg aaaacaaaat tatctcttaa aaaatttgta atgctgtcta
    14161 aatataataa tattttttgt aaggatttca taaaaatgta taccaaatgg ctccattttt
    14221 atgtctccat tcggtagcta tttttaattt ttgggatcta ttcagtatct tttgagtata
    14281 cattcggtct ccatataaca aatttcagcg cataaatggg aatcctattt gacactgtca
    14341 aatcaatgct tttaacaaaa atggctaccg aatggagact ttttgtgcag gattcctctt
    14401 atgctcttta atttaattta aaatgttaaa gttatatttt acacctattt tttaggcttt
    14461 agctttttgc tgagaagagc aatcgagata aaaaatacat ttttctttct aaaagttttg
    14521 agaaagaaat tttaaagcga tttatagctt ctctgttgaa tgaaaaaagt ttttagtctt
    14581 ttattattac gtggaataat aaaatgtcct agaaagggct taaaatgcaa aataaaaaga
    14641 ctactcattt ttcgagtagt ctgaagaata gtttttgatg tattaaatga aagggagtac
    14701 tacattaatc atatcacatg catttatgcc gagaaaattt attgacgttg agcaattgga
    14761 ataatgcaat gtttttagta aattaaaaag aaaaggggtt tttttatgaa gttgtacgtt
    14821 aacgaaatta tcagaacaaa taacttcgaa gatgatgata tgatgaataa aattttaggt
    14881 atgtgggata gtttttataa aaataatgat gattataaag gggaagtata tgcagtttat
    14941 catgattatg aatcggatta taaaggcgat tattcattag ctttgtgtac agaagatatt
    15001 tcggcagata aatttttcga agttgacttt gctgatagta ctgaatataa gtgctctgga
    15061 aaagatgaaa ttataaacgt atggaaacgt atttggggag atgaagaaga aaataagatt
    15121 caaagaagtt attatattga ttgcgaagaa tataaaaaag atgggtcagt tgttatacat
    15181 cttttttagg ttttttgaaa cgagtttcaa aaaagccaaa aaatctcatc gttaaatact
    15241 tttgaatgca ctgtaattaa ataagtgtta aagtaaaaat atagcattat cctcaaacat
    15301 cattaattct tttaacatgt aatagttctt cgcccaacac atagctactc acaaattgag
    15361 tggctatttt ttaatgcttt attccaattg ctttaaagtt atatcactta ttactttttt
    15421 aaataataaa aaccaaccac aaatgtggtt ggtttccttt ttgtcttttg aatttgtgag
    15481 gggcaaattg ccccgaactt tttaatatct ttttataaat ctttttaaaa cctttttagg
    15541 cgtcatttga gccttagagt gacaatggat ttgaaatgct aaaagggacg tttttaaatt
    15601 taagtcactt atatattaag agaggtgttt ttttatgtct ggtgaaacag tagtatatag
    15661 aaatgaaatg aatttagtct cattaagacg ctttacaagt actgaagtag atttattctt
    15721 tacattatgc aataaactta aagagcaaga tacgagaaaa gtaattattc cttttgaaga
    15781 attaaaatat ttaagtaact actacacgcg ttctcaagaa cgctttatta atgatttaga
    15841 gcacgtatac gataaaatgt tgaatctaac atatgtagaa cgtaatggta ggtcttttga
    15901 aaaatttgtt ttatttactt catacaaagt agatttagac gaagaatgtt tatctattag
    15961 tgttaatcct gatttaaaac atattttaaa ttctataaca gctgatttta ctaaatttga
    16021 attaaaagaa atgacgcatc ttaaatctac ttacgctaaa aatatgttta gattgcttaa
    16081 acaatataaa catactggtt atgtaaaaat aaatatagct gattttaaaa atcgtctaga
    16141 tatacctaaa acttatcaaa tgaatgatat aaccaaacgt gtattaaagc ctataattaa
    16201 tgaactttct tcaattttta ataatcttaa tatcaataaa attaaagcaa aaaaaggacg
    16261 taaaattgag tggttagagt ttacgtttga cgctgagaaa cgcattcata acaagcgaca
    16321 acctcaaatg actaatgtag gtaaacaaag acaatatatc agtcgtgaaa aaacgccgag
    16381 atgattagaa gaacgtactt atgaaaaaaa aattaaaaag tgagtatgat ccacaattag
    16441 aaaaagagcg aaaagcattc ttaaaacaac ttcaagttga ttgggaagat taagataaaa
    16501 gatctttagc aagtgtgcta aagatctttt attttgtatt ttattttcct gttaattcag
    16561 gtattaacca acttagaaaa cctccaatag gaaagacaat ccaccaatat ctagccataa
    16621 aatcccagcc attttttaca ggttcacttt ttctattaga tactctattt ttcattccaa
    16681 tagtcatagg atatttttta tctaattttt ttgaaataaa aacatttaaa aaataatgca
    16741 ttattgctaa gatcaaaaac aaagtaaaaa gccaaatgat tccgtaaata ttttgttcta
    16801 aaccgtttaa ctcacctaca aagattccaa atagtcctaa aaacacaaaa ataaaactaa
    16861 atgttattaa tttaatagta aaaagttcac ttttacgata attaaactgc ttttgttgtt
    16921 ctttagatat ttccattatt tcctcctcct tatcagaaga cgagatagat tcgaatagtt
    16981 cattgactgt cacatctaat gcgtttgaga cacttttaag tgtttcacta ctaacttctt
    17041 ctccagcctc cattctttga attgttctta ctgttacata agccttttct gctaaatttt
    17101 cttgagttaa cgatttttgt tttctaattt ctgcaacttt tgatttgttc atactcataa
    17161 actactcctc aactaaaaaa tgaacacgaa aaattaccga cagatggacg acaatgaaac
    17221 gacagttact tcaaaattat attcttaaaa gaaagtatat atctaatttt acaaaaagca
    17281 taagaaagga tatactgaaa ttaacaaata ttgctagcat ttacgcacca aaccccagcc
    17341 tactgcaata ggctggggtt ttttcggtgt tgactatgcc gtcttatttt ttattacgtt
    17401 gttctagcca aaatttaaac aacgcaacac agcactctat aaaaatagat actgttatat
    17461 aaacaaatat cgctaacatt tcatcgcacc ccctctctac gtcaaattga cgtctgagga
    17521 aaagacgact tcatataata taccatgtga gctacgtgat atacattgca taaaaataaa
    17581 aaatttctct ttatgaaaac ttatgaaaac gcatgagatc aatgatgtat aaaagatgca
    17641 taaacgataa tcataaagaa aaggcttaaa cgttgatttc acagcgttta agcctctttg
    17701 atgagttaac ataattaact attatgggta gtgcctttgt ataaatactc aaaaacacaa
    17761 acattgttaa attaatcttt gtgtcctgta atataagtaa cataatagtt aattattgcg
    17821 atgagaaaaa ccatagataa ctaaatatat aagcataata actatgaaat gaatagctcc
    17881 taaaaataat gcgaaaatat ctgtagtaag aggtttaaaa taatctgatg aatcgtaaat
    17941 attcataaac caatgaacac attcccaaga aagaaatgtt ccaatacatc tacttattat
    18001 aatacttata ttatttttta agccgaattt aaaaatagat ctacttatta atatagcaac
    18061 tattataaat gggatgtaac ctattaataa acctgtttga taatcagtaa ataatccgat
    18121 aaattctatt ggaactaaag ataaaattaa tataatgatt tttaaccatt tcattttaaa
    18181 atttctcttt tcaatattat ttttccttca atatcatttt
//
