LOCUS       NZ_CP092799             5596 bp    DNA     circular CON 23-MAY-2024
DEFINITION  Klebsiella pneumoniae strain XH1507 plasmid pXH1507-6, complete
            sequence.
ACCESSION   NZ_CP092799
VERSION     NZ_CP092799.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN26270980
            Assembly: GCF_022533525.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 5596)
  AUTHORS   Hua,X. and Yu,Y.
  TITLE     The genome sequence of Klebsiella pneumoniae XH1507 and XH1508
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5596)
  AUTHORS   Hua,X. and Yu,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-FEB-2022) Sir Run Run Shaw Hospital, Zhejiang
            University, Qingchundong 3 RD, Hangzhou, Zhejiang 310016, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.48
            Assembly Name                     :: XH1507
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300x
            Sequencing Technology :: Illumina; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022533525.1-RS_2024_05_23
            Annotation Date                   :: 05/23/2024 06:08:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,994
            CDSs (total)                      :: 5,874
            Genes (coding)                    :: 5,691
            CDSs (with protein)               :: 5,691
            Genes (RNA)                       :: 120
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 183
            CDSs (without protein)            :: 183
            Pseudo Genes (ambiguous residues) :: 0 of 183
            Pseudo Genes (frameshifted)       :: 67 of 183
            Pseudo Genes (incomplete)         :: 122 of 183
            Pseudo Genes (internal stop)      :: 26 of 183
            Pseudo Genes (multiple problems)  :: 32 of 183
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP092799.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..5596
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="XH1507"
                     /isolation_source="pus"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pXH1507-6"
                     /geo_loc_name="China:Hangzhou"
                     /lat_lon="30.3 N 120.2 E"
                     /collection_date="2019-05-10"
                     /collected_by="Xiaoting Hua"
     gene            82..258
                     /locus_tag="ML258_RS29785"
                     /old_locus_tag="ML258_29785"
     CDS             82..258
                     /locus_tag="ML258_RS29785"
                     /old_locus_tag="ML258_29785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197757.1"
                     /translation="MQKPKKKPLVVKKRSWHPAVMANLMRQAQEEDYRREQMAELERSA
                     RSHFADIGGEDGG"
                     /name="hypothetical protein"
     gene            248..592
                     /locus_tag="ML258_RS29790"
                     /old_locus_tag="ML258_29790"
     CDS             248..592
                     /locus_tag="ML258_RS29790"
                     /old_locus_tag="ML258_29790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_062955149.1"
                     /translation="MAVKRTRFLGIRVTDGEYQQLLERCNGRQLAVWMRETCLDTRPAR
                     SLRLPSIDPVLLRQLAGMGNNLNQIARKINGGQWSGADRVQVVAALMAIDAELERLRHA
                     VLEKGADDDR"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            801..>1235
                     /locus_tag="ML258_RS29795"
                     /old_locus_tag="ML258_29795"
                     /pseudo=""
     CDS             801..>1235
                     /locus_tag="ML258_RS29795"
                     /old_locus_tag="ML258_29795"
                     /inference="COORDINATES: protein motif:HMM:NF015397.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            1270..1779
                     /locus_tag="ML258_RS29800"
                     /old_locus_tag="ML258_29800"
     CDS             1270..1779
                     /locus_tag="ML258_RS29800"
                     /old_locus_tag="ML258_29800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020325392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_032433972.1"
                     /translation="MNSLLTLAKDLEQKSKAQQQSTGEMLKAAFSEHEKSVRAELSESG
                     KRISAAIRAHEQGMSAAMQSNRLSVMRMVGRTWLTITMVSGLLFASLSGVLWYQGSLIA
                     SNLAEIDRQNAALSKLNAKTWGVTYLEDSNGRFLVLPKGTAVDRTQSWTVGNGRSKQNA
                     LRLVKE"
                     /name="MbeB family mobilization protein"
     gene            1786..1998
                     /locus_tag="ML258_RS29805"
                     /old_locus_tag="ML258_29805"
     CDS             1786..1998
                     /locus_tag="ML258_RS29805"
                     /old_locus_tag="ML258_29805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_021527181.1"
                     /translation="MTELEKQLLSALEQLQQDYSKRLDEWESAFGEWRKMSGLMQRENA
                     ALSERVTRLSQQVERLSGQLQRLSR"
                     /name="MbeD family mobilization/exclusion protein"
     gene            2665..2889
                     /locus_tag="ML258_RS29810"
                     /old_locus_tag="ML258_29810"
     CDS             2665..2889
                     /locus_tag="ML258_RS29810"
                     /old_locus_tag="ML258_29810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6290 family protein"
                     /protein_id="WP_000879771.1"
                     /translation="MLAIRLSDEIESRLDSLAKQTGRTKTFYAREAILAHLEDLEDYYL
                     SAETAARVRRGDEAVHSSEDVRKSLGLDD"
                     /name="DUF6290 family protein"
     gene            2873..3139
                     /locus_tag="ML258_RS29815"
                     /old_locus_tag="ML258_29815"
     CDS             2873..3139
                     /locus_tag="ML258_RS29815"
                     /old_locus_tag="ML258_29815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262326.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_004197762.1"
                     /translation="MVWTINYSDRALKSLRKMDKQNARRIVDFMSLRIAVAADPRQSGK
                     PLKGELGEFWRYRVGDYRVLCEIRDDELVILAATIGHRREVYD"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(3209..3559)
                     /locus_tag="ML258_RS29820"
                     /old_locus_tag="ML258_29820"
     CDS             complement(3209..3559)
                     /locus_tag="ML258_RS29820"
                     /old_locus_tag="ML258_29820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197756.1"
                     /translation="MYWLIAFLAFIFPGRSFADGYTAYYRCNGTQEASLTVKDNKLSMV
                     VGLSKFNRQLDTYRFKEKGIEVVMQRAASDDNSEAIMSFIMPDVNNMTLLVKNNGYIIV
                     KTTCWLTKTDKQ"
                     /name="hypothetical protein"
     gene            complement(3625..4170)
                     /locus_tag="ML258_RS29825"
                     /old_locus_tag="ML258_29825"
     CDS             complement(3625..4170)
                     /locus_tag="ML258_RS29825"
                     /old_locus_tag="ML258_29825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_023317533.1"
                     /translation="MFFKRYLTEKEIYKAALPIVRLQGRVNTSLRFLSKYSDVNKNGLI
                     ALHLNLLHFISYNIHGVESLKITQAGINKAVQQSPHADEIKNIAQAIGRKGPEYIEGLI
                     RNPWGKKNDNPLIFIMSIEESIKETLNSGYMLYRVAPITEGEAAAFMDVLKQLLLFEDN
                     FRLFGRDLVYKIEKLKIR"
                     /name="hypothetical protein"
     gene            complement(4196..4522)
                     /locus_tag="ML258_RS29830"
                     /old_locus_tag="ML258_29830"
     CDS             complement(4196..4522)
                     /locus_tag="ML258_RS29830"
                     /old_locus_tag="ML258_29830"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_050516389.1"
                     /translation="MRERTNIMLDIGLKQSLQRLSNKTKMSLSDLINQRLSGSLSVEER
                     IGEKPEWMRNLDPYLANHFSNIELPLPSPLKEYQEKMDEIDSIINDMMVLKEYFRAKFY
                     DEIK"
                     /name="hypothetical protein"
     gene            complement(4880..5038)
                     /locus_tag="ML258_RS30025"
     CDS             complement(4880..5038)
                     /locus_tag="ML258_RS30025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_071596352.1"
                     /translation="MHEPPVQPDCCALSGNYHLESNPDGHAKTPLAAAIGNWIYTREIL
                     RGLEVGA"
                     /name="replication initiation protein"
     Typing          5513..5592
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="90.361"
                     /coverage="97.0"
                     /evalue="1.1100000000000001e-21"
     Typing          complement(4930..5327)
                     /name="rep_cluster_2370"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="89.526"
                     /coverage="91.0"
                     /evalue="3.03e-139"
     Typing          583..2114
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.804"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 actgacgcgc tggcgcttgt ccaacgccgg agcgacccgg aaaacttttc cgtgccgtcc
       61 ggcgtttgcg aaggagggat aatgcagaag ccgaagaaga agccgctcgt cgtaaaaaaa
      121 agatcctggc atccggcagt gatggcaaat ctgatgcgtc aggcacagga ggaagattac
      181 cgccgggagc agatggcaga gcttgagcgt tcagcccggt cacattttgc ggatatcgga
      241 ggagaggatg gcggttaagc gtacccgttt tttaggtatc cgggtgaccg atggggagta
      301 ccagcagctg ctggagcgct gcaatggaag gcaactggcg gtgtggatgc gggaaacctg
      361 tctcgatacg cgcccggcgc ggtcgttgcg gctgccgtcc atcgatccgg ttttgctgcg
      421 ccagcttgcc gggatgggga acaacctcaa ccagatcgcc cggaaaatta acggcggcca
      481 gtggtcaggc gctgaccggg ttcaggtggt ggccgcgctg atggccattg atgccgaact
      541 cgagcggctg cggcatgccg tgctggaaaa gggggcagac gatgatcgtt aagtttcatc
      601 cgcgagggcg aggcggcggt gccgggccgg tggattatct gctggggaaa gaccgccagc
      661 gcgacggggc catcgtcctg cagggaaagc cggaggaggt ccgggagctt atcgacgcct
      721 cgccctacgc caaaaagtac acctccggcg tcctgtcttt tgctgaacag gatttaccgc
      781 ccggccagcg tgaaaagctg atggcgagct tcgagcgggt tctgatgccc ggactcgata
      841 aagaccagta cagcgtgctg tgggttgaac accgggacaa ggggcggctg gaactgaatt
      901 ttctggtacc gaacacggaa ctgctgaccg gcaggcgtct ccagccgtac tacgaccggg
      961 cagaccgtcc gcgcatcgat gcgtggcaga ccgtggtgaa cgggcgactg gggctgcacg
     1021 acccgaacgc accggagaac cggcgcgcgc tggtgacgcc atcttcgtta cccaaaacga
     1081 agcaggaagc cgcagaggct attacgcggg gcttactggc cctcgcctcg tcaggggagc
     1141 ttaaaacgcg tcaggacgtc actgaggcgc tggaaagcgc aggttttgag gtcgtgcgca
     1201 ccacaaagag cagcatcagc attgccgacc cggacggagg gcgaaacatc cgacttaagg
     1261 gagccatcta tgaacagtct tttaacgctg gcgaaggact tagagcagaa atcgaaagcg
     1321 cagcagcaga gtaccggcga aatgctgaaa gccgcattca gcgagcacga gaagtctgtc
     1381 agagcggaac tgagcgaaag cgggaagaga atcagcgccg ccatccgcgc ccacgagcag
     1441 ggtatgagcg cggccatgca gtcgaaccgc ctgagcgtga tgcgtatggt cgggcggaca
     1501 tggctgacca tcacgatggt gtcaggactg ctgttcgcca gcctgagcgg ggtgttgtgg
     1561 tatcagggga gcttgatagc gtcaaatctg gccgaaatcg accggcagaa cgcagcgctg
     1621 tcgaagctga acgcgaagac ctggggcgtg acgtacctgg aagacagcaa cggacgtttt
     1681 ctggtgctgc cgaaggggac ggccgtagac aggacgcaga gctggacggt cgggaacggg
     1741 cggtcgaagc agaacgcgct gagactggtg aaggagtaag tgccgatgac cgagctggaa
     1801 aaacagttgc tgagcgcatt agagcagcta cagcaggact actcgaaaag gctggacgag
     1861 tgggagagcg ccttcgggga atggcggaaa atgtcagggc ttatgcaacg ggagaacgcg
     1921 gcgctgagcg agcgcgtgac gcgcttgagt cagcaggtgg aacgcttgag cgggcaactg
     1981 cagcgtttga gccggtagtg cagcgtcatg agatggccgt ggccgcagaa cgggcgcacg
     2041 agcaacggca gcacgaaaag gaactgacgg aagcgcgttc ccggcagcga agctatgacg
     2101 gtccgtcgct gggctgaaat gcaggaaaac agggttctca tcgggcattt acgctgaaac
     2161 cggatgtcat tcacctggct gcatggctat gcagccaggt aaaatttatc tgtcgcgaac
     2221 ggggcggttt atcgggtggt ttgttgccgg ttttacctga ctgccacccc gttcgcggcg
     2281 aacccgtccg gggcggtgcg ggcaacgggt gttatgttta atcagcgtga acggcagata
     2341 caaaaaagcc ccggagggct tttaactact gacttatttt tttgaagatt tgctgggttt
     2401 caatttgtca gtatttcccg gcgttttttt attgtcacgc tggcgtttat caggttcccc
     2461 tgttgaatcg gcaattcgtt tcggacccgg cttaagaccc ataatcgtta tcctttcaat
     2521 agttaagagg aaagccctca agctagatat attgaccgcg ttacggatta tcaagagggg
     2581 ctaacaagat tattttttgt tcttttaggt tgattgtggt actgttgata tacatgtata
     2641 gcaaatggtg ttcgggaggt ttatatgctt gctatccggt tatctgatga gattgagtcc
     2701 cgtctggact cgctggcgaa gcaaaccggc agaacaaaga cgttttatgc gcgggaagca
     2761 atactggcgc atctggaaga cctggaggat tattatcttt cagcagaaac tgctgcacgc
     2821 gttcgccgtg gtgatgaagc agtgcattcg tctgaagacg tgaggaagtc acttggtctg
     2881 gacgattaac tattccgatc gggcgctcaa atcgttacgc aagatggaca aacagaacgc
     2941 acgacggatt gtggatttta tgagtttacg cattgcagtt gctgccgatc ctcgccagtc
     3001 agggaagccg ctcaaaggtg agctgggcga gttctggcgc tatcgggtgg gagattatcg
     3061 cgttctgtgt gagatccgag atgacgagct tgttatcctt gccgccacga ttggacatcg
     3121 ccgcgaagtt tacgactgaa gcccgctatg cgggcttttt tgatgccgac aacaggtatt
     3181 atggtaaata ctcgactaac tacgtgttct actgtttgtc ggttttagtt aaccagcagg
     3241 ttgtcttaac gataatgtag ccgttatttt taactaataa ggtcatattg ttaacgtcag
     3301 gcataataaa agacattatg gcctcagagt tatcatcaga agcagctctc tgcattacta
     3361 cttcgattcc cttttctttg aatctataag tatccagttg cctattaaac ttagaaagac
     3421 ctacaaccat acttagtttg ttatctttaa cagtaagaga tgcttcctga gtaccattac
     3481 atcggtagta agcggtgtaa ccgtcagcaa aagatcgacc ggggaatata aatgctagga
     3541 acgcaattaa ccaatacata gttgagaatc ttggtattac acatttcact atcctctctt
     3601 tcatttttcg ttcaccatac tttgttatct gatttttaat ttttctattt tataaaccaa
     3661 gtctctacca aaaaggcgaa aattatcctc aaataataat aattgtttaa gaacatccat
     3721 gaaagcagct gcttcaccct cagttatggg agctactcta tataacatat aacctgagtt
     3781 aagggtttct tttatacttt cttcaatgct cattataaat attagtggat tatcattttt
     3841 cttcccccat gggtttctaa ttaatccttc gatgtactca ggtcctttgc gtcctattgc
     3901 ctgcgcaata ttttttattt catctgcgtg agggctttgt tgtacagctt tgtttatgcc
     3961 tgcttgagtg attttcagag actctacacc gtgtatgttg tatgagataa aatgtaataa
     4021 attaagatgc aatgcaatta atccattttt gtttacatct gagtatttgg ataaaaaacg
     4081 taatgaagtg ttaactctcc cttgaagcct aacaattggg agtgctgcct tgtatatttc
     4141 cttctccgtt aaataccgtt taaaaaacat aattctccgc ctccgtatag cgtgcctatt
     4201 ttatttcgtc gtaaaactta gctctgaaat attcctttag aaccatcatg tcattaataa
     4261 ttgaatctat ctcatccatt ttttcttggt attcttttaa tggtgaaggg agcggtaact
     4321 caatatttga aaagtgattg gcgagatagg gatcaaggtt tctcatccat tcaggctttt
     4381 cgccaatgcg ttcttcaact gaaagtgaac ctgataatct ctggttaata agatcactta
     4441 gactcatttt ggttttattc gaaagccgtt gtaaggattg ctttaatcct atatctagca
     4501 tgatatttgt tctttctctc attacccccc cttgctattg cgttttttgt tgcgcacaaa
     4561 gctaccattg cgcattaaga aacgcaataa aaaaggaggg agggagtggt ttgtacatga
     4621 tgtgcagtgc gctgagggca tcagtggcgg gtgtttttcc gtgggatgga tggagctccg
     4681 gggataacag aactgacgat catttaaagg atcttcttga gatccttttt ttctgcgcgt
     4741 aatctcttgc actgtaaacg aaaaaaccgc ctggggaggc ggtttgatcg aaggttaagt
     4801 cagttgggga actgcttaac cgggtaactg ggtatacgag accgcagata ccaaaactgt
     4861 tctttcagtg tagccgcagt taggcaccca cttcaagacc tctcaatatc tctctcgtat
     4921 atatccagtt accaatggct gctgccagtg gcgtttttgc gtgtccgtcc gggttggact
     4981 caagatgata gttaccggaa agggcgcagc agtcgggctg aacggggggt tcgtgcatac
     5041 agcccagctt ggagcgaacg acctaaaccg agccgagata ccagcagcgt gagctatgag
     5101 aaagcgccac gcttcccgaa agggaaaaag gcggaacagg tatccggtaa acggcagggt
     5161 cggaacagga gagcgcacga gggagccgcc ggagagaaat caccggcatc tttaagtcct
     5221 gtcgggtttc gtcctcctct gacttgagcg tccatttctg tgatgctcgt caggggaggc
     5281 ggagcctatg gaaaaacggc aacgccgcat ccttttctcc ggccctttct gatttgagcg
     5341 cctttgcttt atcccgttat ccgtgagtcg gtcacgcccg ccgcagccga acggcaggag
     5401 cgcagctacc gagtgagcga ggaggcgtca tttcatctgt ccgtgcatgg tattgcggac
     5461 gctcctgagc cacatatcac acctgccaca tgaggcactt tcatgaatcg tgctctcatg
     5521 ccaacatagt aagccagtat acacagcgta aacgctgtga ctggttcagg gctgcgcccc
     5581 gaaacccgct aacacc
//
