LOCUS       NZ_CP092596             6925 bp    DNA     circular CON 05-JUL-2023
DEFINITION  Klebsiella pneumoniae strain EFN 299 plasmid p7, complete sequence.
ACCESSION   NZ_CP092596
VERSION     NZ_CP092596.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN26139404
            Assembly: GCF_023920325.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 6925)
  AUTHORS   Saito,R. and Mahazu,S.
  TITLE     OXA 181 producing Klebsiella spp.
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6925)
  AUTHORS   Saito,R. and Mahazu,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-FEB-2022) Department of Molecular Microbiology, Tokyo
            Medical And Dental University, 1 Chome-5-45 Yushima, Tokyo 1138510,
            Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Unicycler hybrid assembly v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 42.7x
            Sequencing Technology :: Illumina MiniSeq; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 07/05/2023 03:40:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,709
            CDSs (total)                      :: 5,585
            Genes (coding)                    :: 5,454
            CDSs (with protein)               :: 5,454
            Genes (RNA)                       :: 124
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 13
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 52 of 131
            Pseudo Genes (incomplete)         :: 73 of 131
            Pseudo Genes (internal stop)      :: 21 of 131
            Pseudo Genes (multiple problems)  :: 15 of 131
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP092596.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6925
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="EFN 299"
                     /isolation_source="sputum culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="p7"
                     /geo_loc_name="Ghana"
                     /lat_lon="4.9239 N 1.7446 W"
                     /collection_date="2018"
                     /collected_by="ENRH_Hospital staff"
     gene            1..840
                     /locus_tag="MKT41_RS28485"
                     /old_locus_tag="MKT41_28475"
     CDS             1..840
                     /locus_tag="MKT41_RS28485"
                     /old_locus_tag="MKT41_28475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001517559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase RepA family protein"
                     /protein_id="WP_000190708.1"
                     /translation="MATHKPINILEAFAAAPPPLDYVLPNMVAGTVGALVSPGGAGKSM
                     LALQLAAQIAGGPDLLEVGELPTGPVIYLPAEDPPTAIHHRLHALGAHLSAEERQAVAD
                     GLLIQPLIGSLPNIMAPEWFDGLKRAAEGRRLMVLDTLRRFHIEEENASGPMAQVIGRM
                     EAIAADTGCSIVFLHHASKGAAMMGAGDQQQASRGSSVLVDNIRWQSYLSSMTSAEAEE
                     WGVDDDQRRFFVRFGVSKANYGAPFADRWFRRHDGGVLKPAVLERQRKSKGVPRGEA"
                     /name="helicase RepA family protein"
     gene            827..1678
                     /gene="repC"
                     /locus_tag="MKT41_RS28490"
                     /old_locus_tag="MKT41_28480"
     CDS             827..1678
                     /gene="repC"
                     /locus_tag="MKT41_RS28490"
                     /old_locus_tag="MKT41_28480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein C, IncQ-type"
                     /protein_id="WP_000240536.1"
                     /translation="MVKPKNKHSLSHVRHDPAHCLAPGLFRALKRGERKRSKLDVTYDY
                     GDGKRIEFSGPEPLGADDLRILQGLVAMAGPNGLVLGPEPKTEGGRQLRLFLEPKWEAV
                     TADAMVVKGSYRALAKEIGAEVDSGGALKHIQDCIERLWKVSIIAQNGRKRQGFRLLSE
                     YASDEADGRLYVALNPLIAQAVMGGGQHVRISMDEVRALDSETARLLHQRLCGWIDPGK
                     TGKASIDTLCGYVWPSEASGSTMRKRRQRVREALPELVALGWTVTEFAAGKYDITRPKA
                     AG"
                     /name="repC"
     gene            2252..3397
                     /locus_tag="MKT41_RS28495"
                     /old_locus_tag="MKT41_28485"
     CDS             2252..3397
                     /locus_tag="MKT41_RS28495"
                     /old_locus_tag="MKT41_28485"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C beta-lactamase CMY-4"
                     /protein_id="WP_015056382.1"
                     /translation="MMKKSLCCALLLTASFSTFAAAKTEQQIADIVNRTITPLMQEQAI
                     PGMAVAVIYQGKPYYFTWGKADIANNHPVTQQTLFELGSVSKTFNGVLGGDAIARGEIK
                     LSDPVTKYWPELTGKQWQGIRLLHLATYTAGGLPLQIPDDVRDKAALLHFYQNWQPQWT
                     PGAKRLYANSSIGLFGALAVKPSGMSYEEAMTRRVLQPLKLAHTWITVPQNEQKDYARG
                     YREGKPVHVSPGQLDAEAYGVKSSVIDMARWVQANMDASHVQEKTLQQGIALAQSRYWR
                     IGDMYQGLGWEMLNWPLKADSIINGSDSKVALAALPAVEVNPPAPAVKASWVHKTGSTG
                     GFGSYVAFVPEKNLGIVMLANKSYPNPVRVEAAWRILEKLQ"
                     /name="class C beta-lactamase CMY-4"
     gene            complement(3803..4087)
                     /locus_tag="MKT41_RS28500"
                     /old_locus_tag="MKT41_28490"
     CDS             complement(3803..4087)
                     /locus_tag="MKT41_RS28500"
                     /old_locus_tag="MKT41_28490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mobilization protein C"
                     /protein_id="WP_000238497.1"
                     /translation="MVKGSNKAADRLAKLEEQRARINAEIQRVRAREQQQERKNETRRK
                     VLVGAMILAKVNSSEWPEDRLMAAMDAYLERDHDRALFGLPPRQKDEPG"
                     /name="mobilization protein C"
     gene            4391..>4924
                     /locus_tag="MKT41_RS28505"
                     /old_locus_tag="MKT41_28495"
                     /pseudo=""
     CDS             4391..>4924
                     /locus_tag="MKT41_RS28505"
                     /old_locus_tag="MKT41_28495"
                     /inference="COORDINATES: protein motif:HMM:NF015354.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /name="MobA/MobL family protein"
     gene            5034..5447
                     /locus_tag="MKT41_RS28510"
                     /old_locus_tag="MKT41_28500"
     CDS             5034..5447
                     /locus_tag="MKT41_RS28510"
                     /old_locus_tag="MKT41_28500"
                     /inference="COORDINATES: protein motif:HMM:NF036929.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncQ-type mobilization protein MobB"
                     /protein_id="WP_010890157.1"
                     /translation="MNAIDRVKKSRGINELAEQIEPLAQSMATLADEARQVMSQTQQAS
                     EAQAAEWLKAQRQTGAAWVELAKELREVAAEVSSAAQSARSASRGWHWKLWLTVMLASM
                     MPTVVLLIASLLLLDLTPLTTEDGSIWLRLVAR"
                     /name="IncQ-type mobilization protein MobB"
     gene            5492..6415
                     /locus_tag="MKT41_RS28515"
                     /old_locus_tag="MKT41_28505"
     CDS             5492..6415
                     /locus_tag="MKT41_RS28515"
                     /old_locus_tag="MKT41_28505"
                     /inference="COORDINATES: protein motif:HMM:NF028103.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-primase RepB domain-containing protein"
                     /protein_id="WP_014344452.1"
                     /translation="MGCERFDIGVRDATTGQMMNREWSAAEVLQNTPWLKRMNAQGNDV
                     YIRPAEQERHGLVLVDDLSEFDLDDMKAEGREPALVVETSPKNYQAWVKVADAAGGELR
                     GQIARTLASEYDADPASADSRHYGRLAGFTNRKDKHTTRAGYQPWVLLRESKGKTATAG
                     PALVQQAGQQIEQAQRQQEKARRLASLELPERQLSRHRRTALDEYRSEMAGLVKRFGDD
                     LSKCDFIAAQKLASRGRSAEEIGKAMAEASPALAERKPGHEADYIERTVSKVMGLPSVQ
                     LARAELARAPAPRQRGMDRGGPDFSM"
                     /name="DNA-primase RepB domain-containing protein"
     gene            6476..6688
                     /locus_tag="MKT41_RS28520"
                     /old_locus_tag="MKT41_28510"
     CDS             6476..6688
                     /locus_tag="MKT41_RS28520"
                     /old_locus_tag="MKT41_28510"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000455501.1"
                     /translation="MEYEKSASGSVYLIKSDKGYWLPGGFGYTSNKAEAGRFSVADMAS
                     LNLDGCTLSLFREDKPFGPGKFLGD"
                     /name="hypothetical protein"
     gene            6690..6896
                     /gene="urfF"
                     /locus_tag="MKT41_RS28525"
                     /old_locus_tag="MKT41_28515"
     CDS             6690..6896
                     /gene="urfF"
                     /locus_tag="MKT41_RS28525"
                     /old_locus_tag="MKT41_28515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007857788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid repression protein F"
                     /protein_id="WP_007857788.1"
                     /translation="MKDQKDKQTGDLLASPDAVRQARYAERMKAKGMRQRKFWLTDDEY
                     EALRECLEELRAAQGGGSDPASA"
                     /name="urfF"
     ARG             2253..3394
                     /name="blaCMY-4"
                     /gene="blaCMY-4"
                     /gene_name="class C beta-lactamase CMY-4"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          4042..4197
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="2.28e-76"
     Typing          19..840
                     /name="IncQ1"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="96.0"
                     /evalue="0.0"
     Typing          4287..6412
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.859"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atggctaccc ataagcctat caatattctg gaggcgttcg cagcagcgcc gccaccgctg
       61 gactacgttt tgcccaacat ggtggccggt acggtcgggg cgctggtgtc gcccggtggt
      121 gccggtaaat ccatgctggc cctgcaactg gccgcacaga ttgcaggcgg gccggatctg
      181 ctggaggtgg gcgaactgcc caccggcccg gtgatctacc tgcccgccga agacccgccc
      241 accgccattc atcaccgcct gcacgccctt ggggcgcacc tcagcgccga ggaacggcaa
      301 gccgtggctg acggcctgct gatccagccg ctgatcggca gcctgcccaa catcatggcc
      361 ccggagtggt tcgacggcct caagcgcgcc gccgagggcc gccgcctgat ggtgctggac
      421 acgctgcgcc ggttccacat cgaggaagaa aacgccagcg gccccatggc ccaggtcatc
      481 ggtcgcatgg aggccatcgc cgccgatacc gggtgctcta tcgtgttcct gcaccatgcc
      541 agcaagggcg cggccatgat gggcgcaggc gaccagcagc aggccagccg gggcagctcg
      601 gtactggtcg ataacatccg ctggcagtcc tacctgtcga gcatgaccag cgccgaggcc
      661 gaggaatggg gtgtggacga cgaccagcgc cggttcttcg tccgcttcgg tgtgagcaag
      721 gccaactatg gcgcaccgtt cgctgatcgg tggttcaggc ggcatgacgg cggggtgctc
      781 aagcccgccg tgctggagag gcagcgcaag agcaaggggg tgccccgtgg tgaagcctaa
      841 gaacaagcac agcctcagcc acgtccggca cgacccggcg cactgtctgg cccccggcct
      901 gttccgtgcc ctcaagcggg gcgagcgcaa gcgcagcaag ctggacgtga cgtatgacta
      961 cggcgacggc aagcggatcg agttcagcgg cccggagccg ctgggcgctg atgatctgcg
     1021 catcctgcaa gggctggtgg ccatggctgg gcctaatggc ctagtgcttg gcccggaacc
     1081 caagaccgaa ggcggacggc agctccggct gttcctggaa cccaagtggg aggccgtcac
     1141 cgctgatgcc atggtggtca aaggtagcta tcgggcgctg gcaaaggaaa tcggggcaga
     1201 ggtcgatagt ggtggggcgc tcaagcacat acaggactgc atcgagcgcc tttggaaggt
     1261 atccatcatc gcccagaatg gccgcaagcg gcaggggttt cggctgctgt cggagtacgc
     1321 cagcgacgag gcggacgggc gcctgtacgt ggccctgaac cccttgatcg cgcaggccgt
     1381 catgggtggc ggccagcatg tgcgcatcag catggacgag gtgcgggcgc tggacagcga
     1441 aaccgcccgc ctgctgcacc agcggctgtg tggctggatc gaccccggca aaaccggcaa
     1501 ggcttccata gataccttgt gcggctatgt ctggccgtca gaggccagtg gttcgaccat
     1561 gcgcaagcgc cgccagcggg tgcgcgaggc gttgccggag ctggtcgcgc tgggctggac
     1621 ggtaaccgag ttcgcggcgg gcaagtacga catcacccgg cccaaggcgg caggctgacc
     1681 ccccccactc tattgtaaac aagacatttt tatcttttat attcaatggc ttattttcct
     1741 gctaattggt aataccatga aaaataccat gctcagaaaa ggcttaacaa tattttgaaa
     1801 aattgcctac tgagcgctgc cgcacagctc cataggccgc tttcctggct ttgcttccag
     1861 atgtatgctc ttctgctcct gcagctaatg gatcaccgca aacaggttac tcgcctgggg
     1921 attccctttc gacccgagca tccgtatgag actcatgctc gattattatt attatagaag
     1981 cccccatgaa taaatcgctc atcattttcg gcatcgtcaa cataacctcg gacagtttct
     2041 ccgtgtaaat aatgttacaa tgtgtgagaa gcagtctaaa ttcttcgtga aatagtgatt
     2101 tttgaagcta ataaaaaaca cacgtggaat ttaggaaaaa cttatatctg ctgctaaatt
     2161 taaccgtttg tcaacacggt gcaaatcaaa cacactgatt gcgtctgacg ggcccggaca
     2221 cctttttgct tttaattacg gaactgattt catgatgaaa aaatcgttat gctgcgctct
     2281 gctgctgaca gcctctttct ccacatttgc tgccgcaaaa acagaacaac agattgccga
     2341 tatcgttaat cgcaccatca ccccgttgat gcaggagcag gctattccgg gtatggccgt
     2401 tgccgttatc taccagggaa aaccctatta tttcacctgg ggtaaagccg atatcgccaa
     2461 taaccaccca gtcacgcagc aaacgctgtt tgagctagga tcggttagta agacgtttaa
     2521 cggcgtgttg ggcggcgatg ctatcgcccg cggcgaaatt aagctcagcg atccggtcac
     2581 gaaatactgg ccagaactga caggcaaaca gtggcagggt atccgcctgc tgcacttagc
     2641 cacctatacg gcaggcggcc taccgctgca gatccccgat gacgttaggg ataaagccgc
     2701 attactgcat ttttatcaaa actggcagcc gcaatggact ccgggcgcta agcgacttta
     2761 cgctaactcc agcattggtc tgtttggcgc gctggcggtg aaaccctcag gaatgagtta
     2821 cgaagaggca atgaccagac gcgtcctgca accattaaaa ctggcgcata cctggattac
     2881 ggttccgcag aacgaacaaa aagattatgc caggggctat cgcgaaggga agcccgtaca
     2941 cgtttctccg ggacaacttg acgccgaagc ctatggcgtg aaatccagcg ttattgatat
     3001 ggcccgctgg gttcaggcca acatggatgc cagccacgtt caggagaaaa cgctccagca
     3061 gggcattgcg cttgcgcagt ctcgctactg gcgtattggc gatatgtacc agggattagg
     3121 ctgggagatg ctgaactggc cgctgaaagc tgattcgatc atcaacggca gcgacagcaa
     3181 agtggcattg gcagcgcttc ccgccgttga ggtaaacccg cccgcccccg cagtgaaagc
     3241 ctcatgggtg cataaaacgg gctccactgg tggatttggc agctacgtag ccttcgttcc
     3301 agaaaaaaac cttggcatcg tgatgctggc aaacaaaagc tatcctaacc ctgtccgtgt
     3361 cgaggcggcc tggcgcattc ttgaaaagct gcaataactg tcacgccccc ctgcaataac
     3421 tgtcacgaac ccctgcaata actgtcacgc ccccaaacct gcaaacccag caggggcggg
     3481 ggctggcggg gtgttggaaa aatccatcca tgattatcta agaataatcc actaggcgcg
     3541 gttatcagcg cccttgtggg gcgctgctgc ccttgcccaa tatgcccggc cagaggccgg
     3601 atagctggtc tattcgctgc gctaggctac acaccgcccc accgctgcgc ggcaggggga
     3661 aaggcgggca aagcccgcta aaccccacac caaaccccgc agaaatacgc tggagcgctt
     3721 ttagccgctt tagcggcctt tccccctacc cgaagggtgg gggcgcgtgt gcagccccgc
     3781 agggcctgtc tcggtcgatc attcagcccg gctcatcctt ctggcgtggc ggcagaccga
     3841 acaaggcgcg gtcgtggtcg cgttcaaggt acgcatccat tgccgccatg agccgatcct
     3901 ccggccactc gctgctgttc accttggcca aaatcatggc ccccaccagc accttgcgcc
     3961 ttgtttcgtt cttgcgctct tgctgctgtt cccttgcccg cacccgctga atttcggcat
     4021 tgattcgcgc tcgttgttct tcgagcttgg ccagccgatc cgccgccttg ttgctcccct
     4081 taaccatctt gacaccccat tgttaatgtg ctgtctcgta ggctatcatg gaggcacagc
     4141 ggcggcaatc ccgaccctac tttgtagggg agggcgcact taccggtttc tcttcgagaa
     4201 actggcctaa cggccaccct tcgggcggtg cgctctccga gggccattgc atggagccga
     4261 aaagcaaaag caacagcgag gcagcatggc gatttatcac cttacggcga aaaccggcag
     4321 caggtcgggc ggccaatcgg ccagggccaa ggccgactac atccagcgcg aaggcaagta
     4381 tgcccgcgac atggatgaag tcttgcacgc cgaatccggg cacatgccgg agttcgtcga
     4441 gcggcccgcc gactactggg atgctgccga cctgtatgaa cgcgccaatg ggcggctgtt
     4501 caaggaggtc gaatttgccc tgccggtcga gctgaccctc gaccagcaga aggcgctggc
     4561 gtccgagttc gcccagcacc tgaccggtgc cgagcgcctg ccgtatacgc tggccatcca
     4621 tgccggtggc ggcgagaacc cgcactgcca cctgatgatc tccgagcgga tcaatgacgg
     4681 catcgagcgg cccgccgctc agtggttcaa gcggtacaac ggcaagaccc cggagaaggg
     4741 cggggcacag aagaccgaag cgctcaagcc caaggcatgg cttgagcaga cccgcgaggc
     4801 atgggccgac catgccaacc gggcattaga gcgggctggc cacgacgccc gcattgacca
     4861 cagaacactt gaggcgcagg gcatcgagcg cctgcccggt gttcacctgg ggccgaacgt
     4921 ggtggagatg gaaggccggg gcatccgcac cgaccgggca gacgtggccc tgaacatcga
     4981 caccgccaac gcccagatca tcgacttaca ggaataccgg gaggcaatag accatgaacg
     5041 caatcgacag agtgaagaaa tccagaggca tcaacgagtt agcggagcag atcgaaccgc
     5101 tggcccagag catggcgaca ctggccgacg aagcccggca ggtcatgagc cagacccagc
     5161 aggccagcga ggcgcaggcg gcggagtggc tgaaagccca gcgccagaca ggggcggcat
     5221 gggtggagct ggccaaagag ttgcgggagg tagccgccga ggtgagcagc gccgcgcaga
     5281 gcgcccggag cgcgtcgcgg gggtggcact ggaagctatg gctaaccgtg atgctggctt
     5341 ccatgatgcc tacggtggtg ctgctgatcg catcgttgct cttgctcgac ctgacgccat
     5401 tgacaaccga ggacggctcg atctggctgc gcttggtggc ccgatgaaga acgacaggac
     5461 tttgcaggcc ataggccgac agctcaaggc catgggctgt gagcgcttcg atatcggcgt
     5521 cagggacgcc accaccggcc agatgatgaa ccgggaatgg tcagccgccg aagtgctcca
     5581 gaacacgcca tggctcaagc ggatgaatgc ccagggcaat gacgtgtata tcaggcccgc
     5641 cgagcaggag cggcatggtc tggtgctggt ggacgacctc agcgagtttg acctggatga
     5701 catgaaagcc gagggccggg agcctgccct ggtagtggaa accagcccga agaactatca
     5761 ggcatgggtc aaggtggccg acgccgcagg cggtgaactt cgggggcaga ttgcccggac
     5821 gctggccagc gagtacgacg ccgacccggc cagcgccgac agccgccact atggccgctt
     5881 ggcgggcttc accaaccgca aggacaagca caccacccgc gccggttatc agccgtgggt
     5941 gctgctgcgt gaatccaagg gcaagaccgc caccgctggc ccggcgctgg tgcagcaggc
     6001 tggccagcag atcgagcagg cccagcggca gcaggagaag gcccgcaggc tggccagcct
     6061 cgaactgccc gagcggcagc ttagccgcca ccggcgcacg gcgctggacg agtaccgcag
     6121 cgagatggcc gggctggtca agcgcttcgg tgatgacctc agcaagtgcg actttatcgc
     6181 cgcgcagaag ctggccagcc ggggccgcag tgccgaggaa atcggcaagg ccatggccga
     6241 ggccagccca gcgctggcag agcgcaagcc cggccacgaa gcggattaca tcgagcgcac
     6301 cgtcagcaag gtcatgggtc tgcccagcgt ccagcttgcg cgggccgagc tggcacgggc
     6361 accggcaccc cgccagcgag gcatggacag gggcgggcca gatttcagca tgtagtgctt
     6421 gcgttggtac tcacgcctgt tatactatga gtactcacgc acagaagggg gttttatgga
     6481 atacgaaaaa agcgcttcag ggtcggtcta cctgatcaaa agtgacaagg gctattggtt
     6541 gcccggtggc tttggttata cgtcaaacaa ggccgaggct ggccgctttt cagtcgctga
     6601 tatggccagc cttaaccttg acggctgcac cttgtccttg ttccgcgaag acaagccttt
     6661 cggccccggc aagtttctcg gtgactgata tgaaagacca aaaggacaag cagaccggcg
     6721 acctgctggc cagccctgac gctgtacgcc aagcgcgata tgccgagcgc atgaaggcca
     6781 aagggatgcg tcagcgcaag ttctggctga ccgacgacga atacgaggcg ctgcgcgagt
     6841 gcctggaaga actcagagcg gcgcagggcg ggggtagtga ccccgccagc gcctaaccac
     6901 caactgcctg caaaggaggc aatca
//
