LOCUS       NZ_CP092582            24653 bp    DNA     circular CON 26-MAY-2024
DEFINITION  Staphylococcus aureus strain VRMSSA-WC111 plasmid unnamed, complete
            sequence.
ACCESSION   NZ_CP092582
VERSION     NZ_CP092582.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN26026639
            Assembly: GCF_022693225.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 24653)
  AUTHORS   Haas,W., Mitchell,K.K. and Musser,K.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-FEB-2022) Bacteriology, NYS DOH, 120 New Scotland Ave,
            Albany, NY 12008, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 81x
            Sequencing Technology :: Illumina MiSeq and Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022693225.1-RS_2024_05_26
            Annotation Date                   :: 05/26/2024 05:53:59
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,914
            CDSs (total)                      :: 2,832
            Genes (coding)                    :: 2,722
            CDSs (with protein)               :: 2,722
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 66 of 110
            Pseudo Genes (incomplete)         :: 47 of 110
            Pseudo Genes (internal stop)      :: 30 of 110
            Pseudo Genes (multiple problems)  :: 31 of 110
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP092582.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24653
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="VRMSSA-WC111"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed"
                     /geo_loc_name="USA"
                     /collection_date="2004-06-24"
                     /collected_by="NYS DOH"
     gene            1..984
                     /locus_tag="MKI52_RS14390"
                     /old_locus_tag="MKI52_002856"
     CDS             1..984
                     /locus_tag="MKI52_RS14390"
                     /old_locus_tag="MKI52_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            <1004..1293
                     /locus_tag="MKI52_RS14395"
                     /old_locus_tag="MKI52_002857"
                     /pseudo=""
     CDS             <1004..1293
                     /locus_tag="MKI52_RS14395"
                     /old_locus_tag="MKI52_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(1492..1872)
                     /locus_tag="MKI52_RS14400"
     CDS             complement(1492..1872)
                     /locus_tag="MKI52_RS14400"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_242414095.1"
                     /translation="MSKSSESFNLHDISPFIKIAILITILNTFILDFKRHFEDLEANHI
                     GFVLKNLYSLLKRKYEPNKYMLISQTKISEKSVTNFLDTAHLHANLKISIKYFKTSPCF
                     SKFLQGFSYQKLRNFNLTLKSP"
                     /name="hypothetical protein"
     gene            complement(2157..2849)
                     /locus_tag="MKI52_RS14405"
                     /old_locus_tag="MKI52_002859"
     CDS             complement(2157..2849)
                     /locus_tag="MKI52_RS14405"
                     /old_locus_tag="MKI52_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            2959..3153
                     /locus_tag="MKI52_RS14410"
                     /old_locus_tag="MKI52_002860"
     CDS             2959..3153
                     /locus_tag="MKI52_RS14410"
                     /old_locus_tag="MKI52_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            4269..4886
                     /gene="cadD"
                     /locus_tag="MKI52_RS14415"
                     /old_locus_tag="MKI52_002861"
     ARG             4270..4883
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            4905..5252
                     /locus_tag="MKI52_RS14420"
                     /old_locus_tag="MKI52_002862"
     CDS             4905..5252
                     /locus_tag="MKI52_RS14420"
                     /old_locus_tag="MKI52_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            5409..5501
                     /locus_tag="MKI52_RS14425"
                     /old_locus_tag="MKI52_002863"
     CDS             5409..5501
                     /locus_tag="MKI52_RS14425"
                     /old_locus_tag="MKI52_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(5673..6644)
                     /locus_tag="MKI52_RS14430"
                     /old_locus_tag="MKI52_002864"
     CDS             complement(5673..6644)
                     /locus_tag="MKI52_RS14430"
                     /old_locus_tag="MKI52_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            6768..7187
                     /locus_tag="MKI52_RS14435"
                     /old_locus_tag="MKI52_002865"
     CDS             6768..7187
                     /locus_tag="MKI52_RS14435"
                     /old_locus_tag="MKI52_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(7713..8558)
                     /gene="blaZ"
                     /locus_tag="MKI52_RS14440"
                     /old_locus_tag="MKI52_002866"
     ARG             complement(7717..8558)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            8665..10422
                     /gene="blaR1"
                     /locus_tag="MKI52_RS14445"
                     /old_locus_tag="MKI52_002867"
     ARG             8666..10419
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            10412..10792
                     /gene="blaI"
                     /locus_tag="MKI52_RS14450"
                     /old_locus_tag="MKI52_002868"
     ARG             10413..10789
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            11056..11649
                     /locus_tag="MKI52_RS14455"
                     /old_locus_tag="MKI52_002869"
     CDS             11056..11649
                     /locus_tag="MKI52_RS14455"
                     /old_locus_tag="MKI52_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            11621..13063
                     /locus_tag="MKI52_RS14460"
                     /old_locus_tag="MKI52_002870"
     CDS             11621..13063
                     /locus_tag="MKI52_RS14460"
                     /old_locus_tag="MKI52_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /protein_id="WP_000790712.1"
                     /translation="MKNKEKYLTNFSEAKRKKATQKYNIIKPFILGEQSLSSISKSKGI
                     ALSTLYRWNKSYKEQGLKGLIYATKADKGTRKIEPKIIDEIERLALMNKRNSIATIHRK
                     TTNYCKENNFDIPSYKQIYSVIKAMPKSVIDFSHQGEKYYQNKYDLIQIRESSRPNEIW
                     QADHTLLDIFILDQKGNINRPWLTIIMDDYSRAIAGYFLSFDAPNAQNTALTLHQAIWN
                     KNDTNWPVCGIPEKFYTDHGSDFTSHHMEQVAIDLKINLMFSKVGVPRGRGKIERFFQT
                     VNQTFLEQLPGYINNNDTPSNLINFHNFEEKLRYFLIEDYNQKEHSTIHTTPISRWNSN
                     HFFPNMPSSLEQLDLLLLEIPKSRKVHSDGIHFQGFRYSNTNLAAYVGEYVLIRYNPND
                     MAEIRVFYRDEFLCTAICPEIADYSIDIKDIQHARSQRRKHLKQNIASPSTTELIKEEK
                     NCGYSPQETTKNVKKLKRYRND"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            13056..13814
                     /locus_tag="MKI52_RS14465"
                     /old_locus_tag="MKI52_002871"
     CDS             13056..13814
                     /locus_tag="MKI52_RS14465"
                     /old_locus_tag="MKI52_002871"
                     /inference="COORDINATES: protein motif:HMM:NF012464.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000164959.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYTAPAEKQSGKSIENRPVFQEVLN
                     FLRMGDRLIVESIDRLGRNYEEIIQTVNYLKDKEVQLMITSLPMMNEVIGNPLLDKFMK
                     DLIIQILAMISEQERNESKRRQAQGIQVAKEKGIYKGRPVLYSPNAKDPQKRLVYYRVV
                     ELLEQGKSISTIAKEVGITRQTIYRIKNSK"
                     /name="recombinase family protein"
     gene            13875..14189
                     /gene="arsR"
                     /locus_tag="MKI52_RS14470"
                     /old_locus_tag="MKI52_002872"
     ARG             13876..14186
                     /name="arsR"
                     /gene="arsR"
                     /gene_name="As(III)-sensing metalloregulatory
                     transcriptional repressor ArsR"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="99.04"
                     /coverage="100.0"
     gene            14186..15478
                     /gene="arsB"
                     /locus_tag="MKI52_RS14475"
                     /old_locus_tag="MKI52_002873"
     ARG             14190..15475
                     /name="arsB"
                     /gene="arsB"
                     /gene_name="arsenite efflux transporter membrane subunit
                     ArsB"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="99.77"
                     /coverage="100.0"
     gene            15496..15891
                     /locus_tag="MKI52_RS14480"
                     /old_locus_tag="MKI52_002874"
     CDS             15496..15891
                     /locus_tag="MKI52_RS14480"
                     /old_locus_tag="MKI52_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent arsenate reductase"
                     /protein_id="WP_000358995.1"
                     /translation="MDKKTIYFICTGNSCRSQMAEGWGKEILGEGWNVYSAGIETHGVN
                     PKAIEAMKEVDIDISNHTSDLIDNDILKQSDLVVTLCSDADNNCPILPPNVKKEHWGFD
                     DPAGKEWSEFQRVRDEIKLAIEKFKLR"
                     /name="thioredoxin-dependent arsenate reductase"
     gene            16271..16564
                     /locus_tag="MKI52_RS14485"
                     /old_locus_tag="MKI52_002875"
     CDS             16271..16564
                     /locus_tag="MKI52_RS14485"
                     /old_locus_tag="MKI52_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726501.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVEKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            16639..18573
                     /locus_tag="MKI52_RS14490"
                     /old_locus_tag="MKI52_002876"
     CDS             16639..18573
                     /locus_tag="MKI52_RS14490"
                     /old_locus_tag="MKI52_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713731.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTTIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLTLKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTPDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            18577..18888
                     /locus_tag="MKI52_RS14495"
                     /old_locus_tag="MKI52_002877"
     CDS             18577..18888
                     /locus_tag="MKI52_RS14495"
                     /old_locus_tag="MKI52_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            18900..19526
                     /locus_tag="MKI52_RS14500"
                     /old_locus_tag="MKI52_002878"
     CDS             18900..19526
                     /locus_tag="MKI52_RS14500"
                     /old_locus_tag="MKI52_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            19764..20407
                     /gene="mobV"
                     /locus_tag="MKI52_RS14505"
                     /pseudo=""
     CDS             19764..20407
                     /gene="mobV"
                     /locus_tag="MKI52_RS14505"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            20474..20974
                     /locus_tag="MKI52_RS14510"
                     /old_locus_tag="MKI52_002881"
     CDS             20474..20974
                     /locus_tag="MKI52_RS14510"
                     /old_locus_tag="MKI52_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273007.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTYFEKYTKQIKAAQMILD
                     DYEWIKSGKSLKKSEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQE"
                     /name="hypothetical protein"
     gene            21337..22197
                     /locus_tag="MKI52_RS14515"
                     /old_locus_tag="MKI52_002882"
                     /pseudo=""
     CDS             21337..22197
                     /locus_tag="MKI52_RS14515"
                     /old_locus_tag="MKI52_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /name="RepB family plasmid replication initiator protein"
     gene            22284..22625
                     /locus_tag="MKI52_RS14520"
                     /old_locus_tag="MKI52_002883"
     CDS             22284..22625
                     /locus_tag="MKI52_RS14520"
                     /old_locus_tag="MKI52_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761344.1"
                     /translation="MKLAEAIKEQRELKRWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRAPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(22840..22935)
                     /locus_tag="MKI52_RS14525"
                     /old_locus_tag="MKI52_002884"
     CDS             complement(22840..22935)
                     /locus_tag="MKI52_RS14525"
                     /old_locus_tag="MKI52_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001002795.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGYWLHKRDKK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            23084..23269
                     /locus_tag="MKI52_RS14530"
                     /old_locus_tag="MKI52_002885"
     CDS             23084..23269
                     /locus_tag="MKI52_RS14530"
                     /old_locus_tag="MKI52_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466617.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSAWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(23485..24228)
                     /locus_tag="MKI52_RS14535"
                     /old_locus_tag="MKI52_002886"
     CDS             complement(23485..24228)
                     /locus_tag="MKI52_RS14535"
                     /old_locus_tag="MKI52_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     ARG             15497..15888
                     /name="arsC"
                     /gene="arsC"
                     /gene_name="thioredoxin-dependent arsenate reductase"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(7714..8558)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             11271..21564
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          1350..1497
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          2..984
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          1116..1285
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
     Typing          21338..22197
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.768"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(23486..24228)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          19765..20138
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.2"
                     /coverage="100.0"
                     /evalue="1.03e-73"
ORIGIN
        1 atgcaaaatc aatattttac agtgcaagaa aattacaaag aaagatttta tcaaatccct
       61 aaagtattct ttaccagtga aaattataaa aatctaacta atgatatgaa aatagcctat
      121 gctatcttac gtgatcgctt aaatttatct attaaaaata gctgggttga tgaagatggt
      181 aacatttact ttgtttattc aaatgaaaag ctaatggaaa tcttaaattg taaaaaagaa
      241 aagttaacaa aaataaaaaa agggttagaa aacgatggtc tactcattca aaaacgacgt
      301 ggtttaaata aaccaaatat tctatattta atgaaaccta ttgtcacaga acgtgatatt
      361 tacaaaatag aaaaagaaga aaacgatgtt gaaccttacg gcgagaagga agttcgaaaa
      421 tcgaacgtcc agaagttcga aaatcgaacg tccagaagtt cgaaaatcga acgtccagaa
      481 gttcgaaaat cgaacactaa tgatactgac tttaatgaca ttgactttaa tgatactgag
      541 aataatgata tgaatgactt gaatgatata aagtacaaaa atgaaattag taatcattca
      601 aatcattcaa atcaatttac acataatttt gatgataaag aaatgctatt gcaagaattc
      661 ccagaacaac taactaatta tttattaaaa tatgattata gagatttaga aatcataaag
      721 gctgttattc ttaaagcaaa aaaatcattt aattcaaggc atgaagatat gcattacatg
      781 ttagaggaca ttgaggatga aatattaact tctttaaaaa gacttaaaaa agctatacat
      841 gataggggag ttaaaggcca aaaggaaaca atcaagtcaa tgcaagctta tttaatgcaa
      901 acaattctaa ctgaacttga agaaacacat gccctttata tgcgccgtaa aaacatgaaa
      961 caatataata tctttaatca ataattcaaa tgattttata acactcgaag agacatcaaa
     1021 atattccgtt aaatcatctg actttttaac tgatgacgac gaaaaaaatc aagaaattgt
     1081 aagtgattta gaaaaaggtt tgtatcgaaa acgtatgtta agttatggtg gattgcttaa
     1141 acaaaagcat aaaattttaa acttagacga tgccgaagat ggtaatttga ttaatacaag
     1201 tgatgaagat aaaacgacag acgaagaaaa aaagcacatt caattaccgc aatttggaat
     1261 ttcgaaaagc aaaattatta tttaagacat tagtgataac tgatgtcttt ttttattgtt
     1321 tttctgtaaa aaagtgctgt cttatttttg tgacaaatgc tgtatgtagt gtcacaaaag
     1381 tgtgacacta cagctttgta tgatatcact ttaaaataac ttaaaaccct tggaatgtct
     1441 ggccttgcca gatctatcat ttttgaatga tagcaaattt cccttatgct cttacggaga
     1501 ttttagagtt aaattaaaat ttctaagttt ttgataagaa aagccctgca ggaatttaga
     1561 aaaacatggg gaagttttaa agtattttat gctaattttt aaatttgcat gtaaatgggc
     1621 agtatctaaa aaattagtca ctgatttttc tgaaattttt gtttgtgaaa ttagcatata
     1681 tttatttggc tcatatttgc gttttaagag actgtataga tttttaagta caaaacctat
     1741 atgatttgcc tctaagtctt caaaatgcct cttaaaatcc aaaataaaag tgtttaatat
     1801 tgtaataagg attgctattt ttataaaagg agagatatca tgaagattaa aactttcgct
     1861 acttttactc atcgtcaatt agataaacaa gttaataggt ttttaaagaa tgatattcat
     1921 gtattagaaa ttcaaacaca cagtaattgg ttatatattt cagctattgt tttttatgag
     1981 gataaataag gaacatcgta tttatgccga aaaaatttat tgatgttgag aagaaccctt
     2041 aactaaactt gcagacgaat gtcggcatag cgtgagctat taagccgacc attcgacaag
     2101 ttttgggatt gttaagggtt ccgaggctca acgtcaataa aacaattgga ataaaatcaa
     2161 cctacagagc atccagctgc aaatgcagtt ccgcaaactg cttcacatac accgccggct
     2221 attggattta cgattgccca tactccacag tagtgagcac atgcataaag tccagccata
     2281 ctacaagcga atgctttgcc gttccatttg aatcctgcat atgttaccgg tctgttttta
     2341 tcaacttttt cagccttata ttcaacgtaa tttttgttaa taagtatttt tccctctttg
     2401 ttttcagtca tacttctttt ttcggcaatg aattttgtga tttttttgtt gtagttatca
     2461 tatattgttt cagaaactac aatttctttt gttttttcat ttttataagc gttattagct
     2521 atgtagccat atgcattttt atcatttgct tctgtagcta gatattttaa tttagaattt
     2581 ttgtcttcta gctttatttt tttaaatcct tcttttttca tttgcttttc gaatttttgc
     2641 atatcttcat ttttattttg caattgttct agaaaactta tttctttctt ggtcatttgt
     2701 gatacttcga tgtttttgct tttcaatttt tctttttgat tttctagtaa agaacttttt
     2761 tgttcttcat ttgcgtaagc attagaaaaa ttcgcgctaa ataccagtag gaacaaggaa
     2821 attattgaaa ataattttat aattttcatt tgatacctcc aagataataa gatattttaa
     2881 ttgtataagt aagcgcttta taaaatcaat atttatttta atatatttat aaacatattt
     2941 ttgaaaggag tctattttat gaatgaaaat ttagaaaaat atataaaaag tttgccactt
     3001 ttaggtttgt taattagtat tttgttaatt gttttattct tttttatttt agatgttgat
     3061 gaagatttat tcgtggtttt tttatactgt ttattgcctt tgatagttaa tttgtctatt
     3121 tatggttttt atgtttttgt taaaagaaag taagattatg aataattttg tttttaattt
     3181 gtatgctttg agggggttgg aaaacggtag gtgtatagat tagatttctt gtttttttga
     3241 aacgagtgtg aacgagtttc ttcttgtctt gatttttgat aaaaacgccc tacaggaatt
     3301 tagaaaaacg tggggaagtt ttaaagaatt ttatgctaat ttttaatttg catgtaaatg
     3361 ggcagtgtct aaaaatagtt attgtttttg ctcaaatttt tgtttttgaa aatagcatat
     3421 atttatttgg ctcatatttg cgttttaaaa gcatatataa gttttagata taaaactata
     3481 tgaatcaccc ctaaatcttt aaaatgccct cttaaaattc aaaataaggg cataaaaaat
     3541 aaaagctacc ccagataaag tgaggtagct ttttctttca tacggtctat ttatttttct
     3601 ttcgacgccg tatcgtcgat gtaattcaaa aaagttatgg gctataaatc tacatcactt
     3661 tttcaagaat gtagtagcaa tattcaacgc aaattaattt ttataactgc tcggaatatc
     3721 tcaagccgtt tctttaattt tgaaataaaa aaatcgacga aggtcgatta cgtttttgca
     3781 catgtcgatt tatccgacgt ataagtgcgc ccttacggga tttaactaga ttataacgac
     3841 gaattttaga cctgtaaagc aataacaatt aggtctacca ggtagataaa gtgtacaaag
     3901 tagaaccgaa aaagttattt attttgaaga tttttcgtag atataatttg ctaataaact
     3961 tcctaaaact gaataaagaa aaatagttaa actcatgtaa tcactccata attctgaagt
     4021 gtctccatgt ctacgcatag acacgcattt atgccgaaaa aatttattga tgttgagaag
     4081 aacccttaac taaacttgca gacgaatgtc ggcatagcgt gagctattaa gccgaccatt
     4141 cgacaagttt tgggattgtt aagggttccg aggctcaacg tcaataaagc aattggaata
     4201 aagcacctat gattatttaa aaatataagt tataatacat tcaaaaatat ttttgaatga
     4261 ggtgtattat gattcaaacg gttgttgctg ctgctgttct ttatattgct acagcagttg
     4321 atttattagt aattttatta atattttttg ctagagcaaa gactagaaaa gaatatagag
     4381 atatttatgt tggtcaatat ttagggtcta ttattttaat attagttagt ttgtttttag
     4441 cttttgtatt aaattatgtt ccagaaaagt ggatattagg tttattgggt ttaataccaa
     4501 tttatcttgg aattaaagtg gctatttatg atgattgtga aggagaaaag agagctaaaa
     4561 aagaattgaa tgaaaaagga ttgtctaaat tagttggtac ggttgcaatt gttacgatag
     4621 caagttgtgg cgccgataat attggtttat ttgttccgta ttttgtgaca ttaagtgtta
     4681 ctaatttatt acttactctg tttgtctttt taattttaat tttcttcttg gtgtttactg
     4741 cacaaaaatt agctaatatt ccaggaattg gagaaattgt tgagaaattt agtcgttgga
     4801 ttatggctat tatttatata gctttaggtt tatttattat tattgaaaat gacactattc
     4861 aaacaatttt aggatttata ttttaattta gggtgtgatt ttatatgagt tatgaaaata
     4921 cttgtgatgt gatctgtgta catgaggata aagttaacaa tgctttaagt tttttagaag
     4981 atgataaatc taagaaatta cttaacattt tagaaaaaat ttgtgatgag aagaaattga
     5041 aaatcatatt atctttgatt aaagaagatg agttgtgtgt ttgtgatatt tctttgatat
     5101 tgaaaatgag tgttgcttca acttcacatc atttaaggct tttatataaa aatgaggtac
     5161 ttgattttta taaagatgga aagatggcat attattttat taaagacgat gaaataagag
     5221 agtttttctc taaaaatcat gagggttttt gaaacgagtt tcttcttgtc ttgatactat
     5281 aaaaaacaaa gttatataac ataagacgac ttatcggaag tagatatgct tgtatattca
     5341 cagatggtat aataatagag tcgcctatct ctcaggcgtc aattgacgaa gagaggaggt
     5401 gcattacttt gctaatcatt ttcgttcaca tcatagcacc agtcatcagt ggctgtgctg
     5461 ttgcgtatta tacttattgg cttagtaaac gcaacaaata attaataggc gactttataa
     5521 gccagcatcg aaaaaatccc cacactactg caatagtgtg gggattggtg cattaattgt
     5581 taatcatttt cgttatataa attataacac tggttagtag agaaatgcaa aatgattgaa
     5641 ttaatagtaa atgtattaat gaatactcac acttatactt ttaaaatagt tcttcctaaa
     5701 tgttgtcctt ttaaaagctg atctatcgtt ttatagaatt cttcaaatcc aatttcattg
     5761 tatagaagtg aatttcctat attccattca tttgctaact tactccatat atcttcacgg
     5821 atattatgat caacatatac agaatcaatg ccaattaatt taatacctct aagaataaac
     5881 ggtaatatat tagcgttaag tgaatttcct gctacatttc cacatacagt agcaacacct
     5941 tgataattta gacgttttaa accgtataat gttacattac tccccactgt atctaagaaa
     6001 taatcaaaaa tacctttttt aagcggttta ttatcatctt caattattat tacttgtttt
     6061 gcacctaatt tttttgcgat ttctatttgc ttttcttttc ttacgatagc agtgatattt
     6121 tcatatccaa ttttatgtaa aatttgtata gcaacactgc ccacaccacc tgtagcccca
     6181 gacactaaaa tttcaggttg tgatttgata ttcattccat atttttctag ttcaaaaatt
     6241 gataatgctg ccgtaaaacc ggctgtgcca tataccatag actctttaat agacatttct
     6301 tggggaatag gaacaatcca ctctccaggc acttgtgcat attctgaaaa tccacctgta
     6361 tgtgtcacgc caacatcata accagtaact aatacattat cgccttcttt aaacttatca
     6421 ttcgaacttg attcaacaat acctgcaaaa tctataccag gaatcatagg ataatctcta
     6481 attacaccgc ctttatattg taaagctagc atatccttat aatttattga agagtatacc
     6541 acttttacta atacatcacc cttcgataaa tgagattcat caactttttc tactttataa
     6601 ctaacatttg atgcactttt tctcactact accgcattga acatttatta gccttctttc
     6661 acaattgttt tgtagaagta tgtttttgtt gcaaaactat tttcctacaa aacttatcat
     6721 gatatgataa gcgagtcaat actaatgatt taagagaggt tttagttgtg gaattagata
     6781 attgtataaa ttatttgttg agtacttctc agaatagagt ttttaaacat tttaaaagtt
     6841 tattaagtcc ctataatatt actccagcag aatatggtgt tttgaattgc ttgattaata
     6901 gtaatttgaa tacacctaaa gcgattggta atactttaaa tttagaacct tcaacaatat
     6961 ctggaatatt agataagatg tccaaaaagg atctaataac acgtcaaact gataatgaaa
     7021 atagaagaac tgtgctaata aacagtacaa ataaagcaaa agacttatgg ccaacattag
     7081 aaaagaaagc ctatcaactt aataatcatt acttcgctaa tttaactaat gaagaaactg
     7141 tagtgtttaa aaagatatta ctaaagataa ataaaactac gttttaattt ttacgttata
     7201 aaaaagttga agtgcgaatt ataatcgagt aaatataaat gatagcttag cttaattata
     7261 tattaaagcc aactatactt ttattcccga aaaacctact atccaaattt ctaagatact
     7321 ttagcctcta taataaacat attgtaatat aatttatgta ttatttaggt ttaccctaat
     7381 cgaacaataa aaaatacttg taaaatgcta ttgtcacttt gcttgatata tgagaattat
     7441 ttaaccttat aaatgagaaa aaagcaacgc actttaaata agatacgttg ctttttcgat
     7501 tgatgaacac ctataattaa actattcatc tattatttat gattttttgt atatacaata
     7561 tttctagttt gttaaagaga attaagaaaa taaatctcga aaataataaa gggaaaatca
     7621 gtttttgata tcaaaattat acatgtcaac gataatacaa aatataatac aaactataag
     7681 atgttatcag tatttattat gcatttagaa tattaaaatt ccttcattac actcttggcg
     7741 gtttcactta tcaacttatc atttggctta tcacttttat tgtctttatt cgtaaaaatg
     7801 actaaaacaa taggttcaga ttggccctta ggataaacaa aagcaacatc atttctagaa
     7861 gcatatgtta ttgcttgacc acttttatca gcaaccttat agtcttttgg aacaccatct
     7921 ttaattaaag tgtctccgtt tttattatta aacattaaat caagtaagaa atttttattt
     7981 tttttgctta attttccatt tgcgataagt ttatttaaag tcttgccgaa agcagcaggc
     8041 gttgaagtat cttttttgct ctttggtgaa tagtaattta attctatctc atatctaact
     8101 ggatttgtta ctttatctcc tagttctttt agacgttgtt taactttttt gattccaccg
     8161 atttctttta taattttatt gtttgctgta ttatcactat atgtcattga agcctcaata
     8221 agttctttta aagtgatatc ttttcctaca tatttttcta aaataggaga ataagcaact
     8281 atatcatctt tgttaatatg tactttttta tttaacttat tataaggtac ttgttctaac
     8341 aaaatagcac tatttatcgc ttttgaagtc gaagcatagg caaatctctt atctgaatta
     8401 aattttactt ccttaccact tttagtattt aaagcataaa caccaatatg agcattatat
     8461 tttttttcta aatcatttaa ctctttggca tgtgaactgt ttgaattaca tgcacttaaa
     8521 actaaagcaa ttacaattaa aaatattaac tttttcaaaa taaaccctcc gatattacag
     8581 ttgtaatttt tataaatcaa taatattaca attgtaatat tgatgtcaat tgtttattat
     8641 aaatatttga aagaaggtgt caaaatggct aaattactaa taatgagcgt agtaagcttt
     8701 tgttttatat ttctattgtt agtatttttt aggtacatat taaaacgcta ttttaattat
     8761 agtttaaatt ataaagtttg gtatctaact atgcttgctg gattaattcc ttttatccca
     8821 attaaattct cttttataaa atttaataat gtgaataatc aagcgcccac agttgaaagt
     8881 aagtcacacg atttgaacca taacataaat accaccaaac ctattcaaga gttcacaaca
     8941 gatatccata agtttaattg ggattcaatt gataatatct gcacagttat ttggatagtt
     9001 ttagttatta ttttaagttt taaatttttg aaagccttat tatatcttaa atatttaaag
     9061 aaacagtcac tttatctaaa cgaaaatgaa aaaaataaaa tagatacgat acttttcaac
     9121 catcaatata aaaaaaatat tgtgattcga aaagcagagg ctattcaatc tccaataact
     9181 ttttggtatg ggaaatatat tattttgatt cctagttcat attttaaaag tgtaattgat
     9241 aaaagactaa aatatataat actgcatgaa tatgctcatg ctaaaaatag agatacttta
     9301 catttaatta tctttaatat cttctctatt attatgagtt acaatccatt agtacatatt
     9361 gtaaaaagaa agataattca tgacaatgaa gtagaagccg atagatttgt ccttaataat
     9421 attaacaaaa atgaatttaa aacttatgcg gaatctatta tggactccgt attaaaaacc
     9481 ccattttcca acaaaaatat attaagccat tcatttaatg gtaaaaaatc attactcaaa
     9541 agtagattaa ttaatataaa agaagccgat ctgaaaaagc agtcaaaatt aattctaatt
     9601 tttatttgta tttttacttt ttttatcatg ataattcaaa gccagttttt aatggggcaa
     9661 tccttaactg attataatta taaaaagccc ttacaaagcg attaccaaat tttagatgaa
     9721 agtaaaaatt ttggttcaaa tagtggatct ttcgttatgt acagcatgaa gaaagacaaa
     9781 tactatattt ataatgaaaa agaaagtaga aaaagatatt ctcctgattc aacttacaaa
     9841 atttatttag cactgtttgg acttgaccgt catattataa gtgataaaaa ttcacgtatg
     9901 tcatggaatc ataaacatta tcttttcgag tcttggaata aggaacaaga tttaaataca
     9961 gcaatgcaaa attcagttaa ttggtacttc gaacgtatta gtaatcaaat accaaagaac
    10021 tatactgcgg ctcaactcaa gcaattaaat tatggtaatg aaaatttggg aagttataaa
    10081 agctattgga tggaagatag tttgaaaata tctaatcttg aacaagtaat agtttttaaa
    10141 aatatgatgg aacaaaataa ccattttagt aaaaaagcaa agaatcaatt atcttcttca
    10201 ttattgatta agaaaaatga aaagtatgaa ctgtatggga aaacaggtac aggtatagta
    10261 aacgggaagt ataataatgg gtggtttgta ggttacgtaa ttacaaatca tgataagtat
    10321 tattttgcta cacatttatc agatggaaac ccgtctggga aaaatgctga attaataagt
    10381 gaaaaaatat taaaaggaat gggtgtttta aatgaccaat aagcaagttg aaatatctat
    10441 ggctgaatgg gatgttatga atataatatg ggataaaaaa tcagtatcag ctaatgaaat
    10501 tgtagttgaa attcaaaaat ataaagaagt tagtgataaa acgattagaa cattaatcac
    10561 aagactatat aaaaaagaga ttataaaacg atacaaatca gaaaatattt atttttactc
    10621 atcaaatatt aaagaagacg atattaaaat gaaaactgct aaaacctttc ttaataaact
    10681 gtatggaggg gatatgaaaa gtttagtgct gaattttgcg aaaaatgaag aattaaataa
    10741 caaagaaatt gaagaattgc gagacatttt aaatgatatt agtaaaaagt aattagaggt
    10801 atgtttcaaa cataatacat atgtaaacca tacttgactc ttattaaatt agttttgtta
    10861 atgacattta aaatatatta ttaaagatga gagtgtccag aaaataacca ttttctggac
    10921 actcttcttt tatgtctaaa taagtaagaa ttacatagga ttatgtgttc aaaaacccaa
    10981 caaaaaatct atgttcataa aaggccttgt aattaagtta tggtacactg aagatgtata
    11041 taggaggttt gtattttgaa aataggttat gcaagagttt caactggatt acaaaattta
    11101 aatttacagg aggatcgatt aaatacatat ggttgtgaaa agatatttaa tgaccatatg
    11161 agtggttcaa aaagtaaaag acctggttta gataaagcaa ttgaatttgc gaggtcagga
    11221 gatacgattg ttgtttggag attagataga ttgggacgta atatggagga tttaatcaca
    11281 ttagttaatg agcttaacga acgaggtgta agtttccata gtttagaaga aaatataaca
    11341 atggataaat caagttcaac tggacaatta ttatttcatt tattcgcagc atttgcagaa
    11401 tttgaacgta atttaatttt agagcgttct tcagctggcc gaattgcagc acgtgctaga
    11461 ggccgatatg gaggcagacc agaaaaatta aatcaaaaag atttaaactt acttaagaca
    11521 ctttatgata atggcacgcc aattaagaca attgcagaac agtggcatgt ttcacgtaca
    11581 acaatttatc gttacctcaa taaattggag gacaaggaag atgaaaaaca aggagaagta
    11641 tctaactaat ttttctgaag ccaaacgtaa aaaagctact caaaagtaca atattataaa
    11701 accttttatc ctaggcgaac aatctttatc aagtatttct aaaagtaaag ggattgcgtt
    11761 aagcaccctt tatagatgga ataagtcata taaagaacaa ggacttaaag gactaatcta
    11821 tgcgacaaaa gctgataaag gaacacgtaa aatagaacca aagataattg atgaaattga
    11881 acgccttgcg cttatgaata aaagaaatag tatagccaca attcatagga aaaccactaa
    11941 ttactgtaaa gaaaataatt ttgatatacc aagttataaa caaatttata gtgttattaa
    12001 agcgatgcct aagtctgtta ttgatttctc tcatcagggt gaaaaatact atcaaaataa
    12061 gtacgattta atacaaatta gagaatcctc gagacccaat gaaatatggc aagcagacca
    12121 tactttgcta gatatcttta tattagacca aaaaggtaat atcaatagac catggctaac
    12181 tattattatg gatgactata gtcgtgcaat tgcaggctat ttcttaagtt ttgatgcccc
    12241 caatgctcaa aacacagcat taacactaca ccaagcaata tggaataaaa atgataccaa
    12301 ttggccagtg tgtggtatac ccgaaaaatt ctacacagat catggaagtg actttacttc
    12361 acatcatatg gaacaagtcg ctattgattt gaaaattaac ttgatgtttt cgaaagttgg
    12421 tgttcctcgt ggtcgtggaa aaatagaacg attctttcag acagttaatc aaactttctt
    12481 agaacaactg cctggatata taaacaataa tgatactcct agtaatctaa taaattttca
    12541 caattttgaa gaaaaattac gttacttttt aattgaagat tataatcaaa aagaacatag
    12601 tactattcat accacgccta tcagtcgttg gaatagtaat cactttttcc ctaatatgcc
    12661 gagtagctta gaacaacttg atttattatt gttggaaata cctaaatcta gaaaagttca
    12721 ttcagatggc attcattttc aaggttttcg atacagtaat actaatctag cagcttatgt
    12781 aggtgaatat gtactgattc gttataaccc aaatgatatg gctgaaatac gtgtgtttta
    12841 tagagatgaa tttctttgta ctgctatatg tccagaaata gctgattact ccatagatat
    12901 aaaagacata cagcacgctc gtagtcagag aagaaaacac ttaaaacaaa atattgctag
    12961 tccaagtacc acggaattaa ttaaggaaga aaaaaattgt ggttattcac ctcaagaaac
    13021 gactaaaaac gtcaaaaaat taaagaggta tcgtaatgac taaaaatcaa aatttcattg
    13081 aaacgaaaga gtataaacgc tttgctgaat tttgtgatgc ttgtattaaa tatcagtata
    13141 ttggtatatg ttatggtcaa cctggtgtcg gaaaaacttt atcgtctagg tattacacaa
    13201 attgggatac tattgaaaaa caagttaacc atagaggttg ggaagattta gctagtaaaa
    13261 cgaccgatga catactatcg gtggataaaa tattttatac tgcaccagca gaaaaacaat
    13321 caggtaaatc tatagaaaac agacctgttt ttcaagaagt attaaatttt ttaagaatgg
    13381 gagatcgttt aattgttgaa tctattgata gactaggaag aaattacgag gaaataattc
    13441 aaacagttaa ttacttaaaa gataaagaag ttcagctcat gataacgagt ttacctatga
    13501 tgaatgaagt cattggaaat ccactactag ataaatttat gaaagattta attattcaaa
    13561 ttttagcaat gatttcagaa caagaaagaa atgaaagtaa acgtcgacaa gctcaaggga
    13621 ttcaagtcgc caaagaaaaa ggtatatata aagggagacc tgttctgtat tctcccaatg
    13681 ctaaagaccc acaaaagcgt ttagtttatt accgagttgt tgaattactt gaacagggta
    13741 aatctataag tactatagct aaagaagttg gtattacacg tcaaactata tatagaataa
    13801 aaaatagtaa ataaagtaac atagacaata atctatatag atgttaatct atttaatatc
    13861 taggaggttt attcatgtct tataaagaac tatcaacaat attaaaaatt ttatcagatc
    13921 caagtaggtt agaaatatta gatttacttt cttgtggtga gctatgcgct tgtgacttat
    13981 tagaacactt tcaattctca caacctacac taagtcatca tatgaagtca ttagtagata
    14041 atgaattagt tacaacacga aaagatggca ataaacattg gtatcaactt aatcatgcta
    14101 ttttagatga tattatccaa aacttgaaca tcattaatac atctaatcaa agatgtgtat
    14161 gtaaaaatgt gaaatcaggt gactgttgat gactatttta gcaattgtaa tttttctttt
    14221 aactttaacc tttgtgattt ggcaaccaaa aggtttagat attggtatta cagctttaat
    14281 tggagcggtt gttgctatca ttacaggagt cgtaagtctt tctgatgtat tagaagtaac
    14341 aggtattgtt tggaatgcaa ctttaacttt tgtggctgtt attcttattt cattaatatt
    14401 agatgaaatt ggtttttttg aatggtctgc gatacatatg gtcaaggctt caaacggtaa
    14461 tggcttaaaa atgtttgttt ttattatgtt acttggggca attgtagcag catttttcgc
    14521 aaatgatggt gcagctttaa tcttaacgcc tattgtatta gcgatggtaa ggaatctagg
    14581 atttaatcaa aaagtgattt tcccctttat tattgccagt ggttttattg ctgatactac
    14641 atcacttccc ttaattgtaa gtaacttagt taatatcgtt tctgcagatt acttcgatat
    14701 tggatttatt gaatatttta gccgaatgat cattcctaat atattctctc tgattgctag
    14761 tattctcgtt ttatggttat atttcagaaa atccatacct aaaacgttcg atacagaaaa
    14821 tctatcagat cctaaaagtg caattaaaga ttctaagtta tttaagcttt catggatagt
    14881 attagcagta ctactcgttg gatatcttgt tagcgagttt atccaaattc ctgtatcaat
    14941 tattgctggt attattgctt ttatctttgt aatattagct cgtaaatcta aagcagttca
    15001 tacaaaacaa gtgattaaag gtgcaccatg gaatatcgtt gtattctcta ttggtatgta
    15061 tcttgttgtg tttggactaa aaaatgtagg tattacaacg gtccttgggg atgttttaac
    15121 aaacatttca aattatgggt tatttagcag catcatgggt atgggcttta tagctgcttt
    15181 cttatcttcg attatgaaca acatgccaac tgttttaata gatgcaatag cgattggcca
    15241 atccagtgct acaggaatat taaaagaagg catggtttat gcgaatgtca taggttctga
    15301 tttaggacct aaaattacgc caattggttc tttagcaaca ttattgtggc tacatgtctt
    15361 aacacaaaaa ggtgtgaaga tttcgtgggg aacatacttt aaaactggaa ttatcatcac
    15421 tattccagtc ctatttgtaa cactcttagg tttatacctt acactaatca tattttaaga
    15481 aaaggggctt taattatgga taagaaaaca atttatttta tatgtacagg aaactcttgt
    15541 cgtagccaaa tggctgaagg ttggggaaag gaaatattgg gtgaaggttg gaatgtctat
    15601 tctgctggta ttgaaacaca tggtgttaat cctaaagcaa tagaagctat gaaagaagta
    15661 gatattgata tatcaaacca tacgtcagac ttgattgata atgatatttt aaaacaatca
    15721 gatttggtcg taacgttatg tagtgatgca gacaataatt gtcctatttt accaccaaac
    15781 gttaaaaaag agcattgggg ttttgatgat ccagcaggta aagaatggtc agaattccaa
    15841 cgtgttagag acgagattaa attagctata gaaaagttta aattgagata atcataaaca
    15901 cctcttattt agttaataag aggtgttttg ccatttaaag aacaaaattt gtgccatata
    15961 caatatgccc tctctttttc tcattaacga acgtttataa cgcaatcatg atgagagtat
    16021 taatacagtt aattatttga aatactttag tttacataat gttgaattat aggtagtgaa
    16081 attgtattta ttatacattg tcatatcgtt gtttaatgat agttaattta aggataatag
    16141 aattaatatt atatatagat gaacaaaaca agcaacagag caaaaaaaca cttttagatt
    16201 atttttactc attctctatt ttatttattt ttgctataat aaataaagaa tattaaatgg
    16261 agttgttttt atgaaaaaga aatttgtttc tagttgtatt gctagtacaa tcttattcgg
    16321 cactttatta ggtgtaactt ataaagctga agctgcaaca gtacatgtag ctggtggtgt
    16381 ttggagccat ggtattggaa aacattacgt atggtcttat tatagtcaca ataaaagaaa
    16441 tcatggttca acagcagtag agaaatattc atcttttagt ggtgttgctc gacctggtgt
    16501 tcaatctaag gcatctgctc caaaggcttg gggtggaaac aaaacatttt atagtcttca
    16561 ctaattacat atattaatta aggagaatag acagaattaa gtaaacttaa ttctgtctat
    16621 tctcttgaaa gaggcaatat gaaaaaattc aaattatttt tagattttag tactttatta
    16681 ttaatttcag ggctattatt tttatttttc ttcaaagaaa atgaagaaat tatacctgaa
    16741 agttccaata ttttaacaat ctctaattgg gataaatcta acagtaaatc aaaagtgtta
    16801 gatgtcattg aatcaggcgc caaaaatcaa aatatacaaa taattaaatc cgttaaagat
    16861 tttgataata aaaaagaatt ttttgttttc aactcaaaac gaaataattc tgactttata
    16921 cgtaataaaa catcactttt aactccatca gatttattaa acagagagat aaaaggaaag
    16981 tattatatta ttggtgaaca tttcaatgta gaagagctta cgagtgaatt aaaaaaagct
    17041 ggtttaacat ctgaagttga atacataaat agaaacatat tattttttga attagtcata
    17101 gataatgatt tattagtgcc tttcatattc ttaggcgtat tatatctttt gtacttctta
    17161 tatgacagag gatataattt gaaattttat gctattcaaa agctacatgg cttttcaact
    17221 acacgcatta tttttcataa tattcatata aaaatcattt attggctagt acttaccact
    17281 attttcttta ttgctaatat attaatcatt catatagcca atttagaatt ggatttctta
    17341 atgtttattc gtagatttat cgtgttgctt tttgtttttg cttgtattac tacattgttg
    17401 tggctgattt cgtatagtct tcttttgaag ttaagtattc cattaacctt aaaagggaaa
    17461 aaaggatata agttttcaat atttatgggt accttcacca aatgtatcat ggtgctaata
    17521 ctatcttttt tactggcaca aaatttaaat gcttatacga agttaaagaa tatatatgac
    17581 tctgaaaaaa tctggcaaaa gttagataat tactatacat tagagatttc tcctaatatt
    17641 agaaattcag aagaaaaaca aattttagaa actaatatat acaatttaat taagaaaagc
    17701 gaacaacttg gtggattgct tttaaagaat aataatatag ccaatcccga taaaaacaat
    17761 tacattcctg aaaatggcaa tgtctttttt atcaataaca attttctgaa tttctataaa
    17821 aatataaatc atgattttaa aatgattgac aatcattcgg ataaaataaa cgtgtttatt
    17881 cctccaaggt tacaatatca aaaatctgaa attcaaaaaa atcaccaagg atggattgac
    17941 tttcaaaagc aacaaaacaa aaaagtagat gtgcaagtac tgtcaaaaaa cgtatctgtt
    18001 ttttcttttg atcgcacaac taatttgaaa tttggatatc tagattctcc aatagtaatg
    18061 ttgttgacac ctgacgattt aacaggagat ttttatttag ctgctgtttc tcaaggtgga
    18121 tatctattta aagatttaga tacacttaaa cagttgctta aagataatca cctagaagaa
    18181 gaaattagcg gtataactaa ttacaaggat tctgtgttaa atgaattaaa tgaaacgaaa
    18241 acaaaaatga taataacaat agttactatt attattaacg ttttcattct tttgatagct
    18301 actgtatttg aaacaattca atattttagc tggaataaaa agcaactatt attaagaaaa
    18361 attcatggtt attcattatt cagcagtaat gtacgttatt taacaatttc tattttactt
    18421 tctattatgt tagcttacac tacgcatatt ttatttggtt caaagatatt actattcata
    18481 ataatgtcta ttgctattat tcaacattta cttcaaattg cttatattaa atatcttgaa
    18541 aaatacttta aagatttaat gagggagatt taaacaatga aaagaacttt aattattgta
    18601 acaattgtac tattaatcat catacttagt ctgttattgg ttagaaatga gcatttagat
    18661 cgttttaacc cactgttaaa agaaaaagta tcttatgcca aagttccaaa agatacccag
    18721 gactatagaa atataactgt atactctaaa aatggagaaa aaaagagtta taaattggat
    18781 tttttaggtt atgatcctac aaaagaatat gtgaaagtaa atcataaagg gaaatatgtg
    18841 cgttcgatag aatacattac aaaagatatt cctagctttt taaaatgagg tgaccgatag
    18901 tgataaaact tgaaaatgtt tttgtaaaaa aaggtaataa aaacatttta gacggatgta
    18961 actttaattt tgaaaaagga aaatcatatg ctttagttgg agaaagtggc gctggaaaat
    19021 ctactttact taacataatc gctgggttcg aagatgtatc acaaggaagc atatatattg
    19081 aagataagtt actaaaaaag aaagtcgatt tttatagata tacgttaggg tatttgtttc
    19141 aaaattttgc tttacttgaa aatcaaacaa tcagtcaaaa tttagattta gccctaaagt
    19201 tcaaaaagaa taaaaaagat aatatgaact taaagaaaga agtattaaaa aaggtcggcc
    19261 tagatttaga tatcaagaga attgttagtt ctctaagcgg tggtgaacaa caaagagtag
    19321 cattggcaag attaatatta aaagatccga aaatcatttt agctgatgaa cctactggat
    19381 cactagatac gaaaaatgga aaaatagtta ttgatttatt attgaagcta cttgatgaaa
    19441 ataaaactat gattgtcgta acgcatgatt tagagcttgc gaaacgattt gatgtcatag
    19501 tcaatatttc tgagcttaga agttaagaaa tattgatagg tatagccata catagagaaa
    19561 aaacaatatg aaatatgatt agtcattact tttgagtttt ttaatttaag gactggattt
    19621 tccagtcctt ttttgtgatg acaaaaaaca agcctcgcag agcacacgtt tttaatgact
    19681 tatttggttt ttaataagtc tagtatgtta aaacttttct gtgtttaggt gttataatca
    19741 tatgcagtgg aagttgattt attatgtctt attcaattat tcgagttgtt aaagtgaaat
    19801 caaaaacaaa tacaagaggt attcaaagag aaaataaaaa ttatgaaaat atagatattg
    19861 atttaagtaa gtcatattta aactatgatt tagtcaatga tactaagttt gattttaata
    19921 aaaaaattga tgagaaaatc gaacaaaatt ataaagggaa acgcaaaatt agaacagatg
    19981 ccattaaaca tattgatgga ttaattacat cagataatgt gtttttaatc aattatctga
    20041 agaagagaca aaatagtttt ttaagcatgc taaagcgttc ttggaagaag aatacggtaa
    20101 agaaaatctt ttatatgcga cagtacatat ggatgagata acaccacata tgcattatgg
    20161 cgtaattcct attactaaag atggacgttt aagtgcgaaa gaagttgtag gtaataaaaa
    20221 agcattaacc gaattccaag atagattcaa tacgtatatt aataagcaag gctatgattt
    20281 aaaacgagga atttctagac aacttacaaa agaaaaacat gatcaagtta gcggctataa
    20341 acaaaaaaca gaatatcata aacaaatgta tatgcgcgag aagcaaatag aggatcattt
    20401 aaagtaagaa aatgataaat tgatacaaaa ctaccaaaaa tcattagata cgcttaaaaa
    20461 gcttctgagt gtcatgtatg aaattaaaac taaaaatgta ggtggatggt ttcataaaga
    20521 gaagcaagaa acaggcaata ttgtaattac taaaacttat tttgaaaaat acactaaaca
    20581 aattaaagca gcacagatga tattagatga ttatgaatgg attaaaagtg ggaagtcatt
    20641 aaaaaaatca gagaaacaaa atgaaagttt agttaatgaa ttgactagtg tccatatgga
    20701 aaatgaaaag ctggttgaag aatttaatga tttagcacaa cgttataatt atttgttgtc
    20761 agagaatgaa aagaaagata aagaactaaa ttatacgctt aagttattca atcaagtttt
    20821 taaaatcatt aaaagtatga tgaaagaaga gcgttatcat acgctaataa atcatattga
    20881 taatcattta gacaattcta aaatacgtga agtaatgacg atagataaca atgatgaaca
    20941 gttctttaag aagaaatatc aagcacaaga atgagaaatc atttttaaag aagatagaga
    21001 agatggttat acattataaa aatagatatt taaatgcatt tgtttgaggt taattatttt
    21061 ttaggatgaa aaataggtag cccccctcta actttttaat atatttttat aaatcttttt
    21121 aaaaatcttt taggggcttg ttcagaccta gagcaacaag ggatttcaat gcctaaagga
    21181 gtgtttttgc cacataaaag gggtgtttta aaaagttgta ctccttttat ggtttgacat
    21241 tgataataaa gtagtttatt gtgaataaaa gttttcaaat gggagtgtat attcaaacga
    21301 tactccttta ggttcgtaat aaaggggggc tgtatcatga caggagagac agttgtatat
    21361 aaaaatgaaa tgaatttagt tccattaagg cgatttacag ctactgaaat taatttattt
    21421 tttgcgatgt gtaataaatt aaaagagcaa gatactaata cattacgttt gtcttttgat
    21481 gaataaaaaa aattaagtaa ttatagtcca gaaacacgta atattaatag atttgctaat
    21541 gatttagata atgtgtataa aaagatgttg aatttaacca ttagatatga agatgatgat
    21601 gtaatagaaa gattcgtttt attcaatcat tatagaatcc ataagcgaga acaatatcta
    21661 gaaatatcaa cttcttcaaa tttaaaacac atattgaatt caattactaa taattttaca
    21721 aaatttgaat taaaagaaat gactaggctt aaatctacat attctaaaaa tatgtttaga
    21781 ttacttaaac aatacaaaca tacaggctat ttaaaaattc acatcgatga ttttaaaaat
    21841 cgtttagata tacctaaatc ttatcgtatg actgatatta acaaaaatgt ttttaaacct
    21901 attattattg aattaggttc tatatttaat aatcttacta tcaataaaat caaagctaaa
    21961 aaagggcgta aaattgaatg gatagagttc acatttgacg ctgagaaacg cattcataac
    22021 aaacgacaac ctcaaatgtc caagatagat aaatcaagac aatatgtgag gcgtgaaaag
    22081 acgcctaaat ggttagaaga acggtcatat gaaaagcaac ctcaaaaaga ttacgaccca
    22141 caattagaga aagaacgaga ggatttttta aaacaacttg aactgaattg ggaataacgc
    22201 aacttttcgt tgcgagttgg ttaactaaaa gtatcgtgac ttttcaatta ttttaattat
    22261 agtttgagtt aaggagtgat tttatgaaat tagctgaagc tataaaagaa cagagagaat
    22321 taaaaagatg gtctcaagag gaattagcca atatattaaa ggtttccaga caaagtgttt
    22381 ctaaatggga aagtgccaaa aactatcctt ccttagatat tttgattgct atgagcgatt
    22441 tatttggaat ctctttagag catttaatta aaggagatgc acgttttaaa aaagttattt
    22501 tagagggaaa ttatagagag agtaacaggg caccttccat agttgatttt ctttatgatt
    22561 tttggtggct tttctttcct gttgccggat ttttagtttg ggccattcat tcgttcatgg
    22621 gttgatttta aaatcaaaat ttaatgcaca tcaggcaata tgaaaaagga aagtattttt
    22681 acgacacctt gaaatgtatt gataagaata gaagagttta caaaaggcaa tatgaaatat
    22741 atactaaaag taacaagaat ttcgtttgta aacgcaccaa accccgaact attcgccgta
    22801 gttcggggtt ttttggtgaa ttggctttaa tcgtctatat tattttttat cacgtttatg
    22861 gagccaataa ccaaataacg taacgagaca accactgatt gccgttgtca tgatgtgaac
    22921 aagaatttca ttcataaatc gcacctcctc tctacgccga attgacgtct gagagataga
    22981 cgaccttcac attataacaa atctcttctt ccatgaaata acatgaatat taataaatgt
    23041 tgttatatat taaagataaa taaatataag ggtgggattg ataatgtttg gcgatcaaag
    23101 acaagaagct acaaaatatg tcattaaaga aggttatcaa gatatttatt tcctcaacaa
    23161 aaacggggaa tggtattatt tcgaagtaag aagtgcctgg cgtggcaaac atattattag
    23221 agttaaagat ggtttgttag gttggagaaa agaaatagta actgaataaa gatacaaaat
    23281 acttgccaat gcaaaagaat gaaaacgcgt caaatcaacg atgtataaaa gatgcataaa
    23341 agataatgaa agtaaaaaac cataaatgcc tatatgacgg catttatggc tttttgtttg
    23401 gttaacataa tcgatgatta ccagaagttc tcactatata aaagacacta aaattttata
    23461 acttttagtg cctaatcaat tattttagct accaaacaaa cgactccaaa accccttttt
    23521 aggttccgtt tcttcactct tttcttctat atcactatca ttgtcattta gattagctgg
    23581 aacgtcttct ttttttgctt cttcaccttg tgtactttcg tcgctttgac ttccagatat
    23641 atccttatat tgaatctctg tttctttagt ttcttcctga tctctgttaa tatttacagg
    23701 attagtagta tatgtttttt cttgtgcatc aacgttttgt ctagtgttag tagatgtatc
    23761 aaagggataa ttaaggtgtt tttctttttc taattgattt tctaattttt gaatcttttt
    23821 attactctct aatgccagaa cttgctgatt ttcaagcaat tttgatcttt cttgcaactc
    23881 ttttctgtaa aattcaattg ttgtttcatg acgactttct tgtttttcaa tttgattatt
    23941 taaagtatca atctgatttt taaggatttc tactatttga gcatcgcttt tcgattcaaa
    24001 attaatatta tccgaccctt ttttttgttt gtcttcagta gtactttcaa aaccatattt
    24061 ctttttattt tcatttactc tttgaatgat tttttctata tcggtatctt ctttaataaa
    24121 cgaagtgttt tcctgtttta ttgtctctat attcaatcgc ttaatattat taaaaatcgt
    24181 ttgcttacta acccctaatt cttcactcaa ctttttcaca cttttcatat catcaaccct
    24241 ttataaaatg tttataaacc cttgataaaa tattataagc ttataatgct taataataaa
    24301 gtgattaata aataaaaata aacatccatc aaccttttta tcaagggttt atgaaaggtt
    24361 tatgatattt atcaagggtt tataaaccct tgataaagct atattttccc ttttataagt
    24421 ttatttaaag tgctataata aacttaatat aacaaaaacc ccaactactg gtaatagtcg
    24481 gggtttggta ataaaacgtt tagaaactgt ttatttatat aattttcgat acttgtatta
    24541 tataatgaat aatatcttag tgcaagcacc taaatcatta aataaatgta aagctaaata
    24601 aaaacgtttt attacctctt accaaactaa aatatggaaa gaggtttttt gtc
//
