LOCUS       NZ_CP092516            22211 bp    DNA     circular CON 05-JUL-2023
DEFINITION  Klebsiella quasipneumoniae strain EF262 plasmid p4, complete
            sequence.
ACCESSION   NZ_CP092516
VERSION     NZ_CP092516.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN26096228
            Assembly: GCF_023920245.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella quasipneumoniae
  ORGANISM  Klebsiella quasipneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 22211)
  AUTHORS   Saito,R. and Mahazu,S.
  TITLE     OXA 181 producing Klebsiella spp
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 22211)
  AUTHORS   Saito,R. and Mahazu,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2022) Department of Molecular Microbiology, Tokyo
            Medical And Dental University, 1 Chome-5-45 Yushima, Tokyo 1138510,
            Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 25-OCT-2021
            Assembly Method :: Unicycler hybrid assembly v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 53.0x
            Sequencing Technology :: Illumina MiniSeq; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 07/05/2023 03:44:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,551
            CDSs (total)                      :: 5,429
            Genes (coding)                    :: 5,291
            CDSs (with protein)               :: 5,291
            Genes (RNA)                       :: 122
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 45 of 138
            Pseudo Genes (incomplete)         :: 87 of 138
            Pseudo Genes (internal stop)      :: 30 of 138
            Pseudo Genes (multiple problems)  :: 20 of 138
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP092516.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..22211
                     /organism="Klebsiella quasipneumoniae"
                     /mol_type="genomic DNA"
                     /strain="EF262"
                     /isolation_source="HVS"
                     /host="Homo sapiens"
                     /db_xref="taxon:1463165"
                     /plasmid="p4"
                     /geo_loc_name="Ghana"
                     /lat_lon="4.9239 N 1.7446 W"
                     /collection_date="2018"
                     /collected_by="ENRH_Hospital staff"
     gene            19..894
                     /locus_tag="MKM89_RS27520"
                     /old_locus_tag="MKM89_27515"
     CDS             19..894
                     /locus_tag="MKM89_RS27520"
                     /old_locus_tag="MKM89_27515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004098982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="WP_004098982.1"
                     /translation="MNENVYIGEVIGPDCESVNNKLTVTSKATVQPVALMRLNVFVPSS
                     RPAKGTRTSIDATSVLKDLEFSRREGYDDIRITGERLSMAIDFKVWVGIIEAFSKYGLK
                     TNSIKLTFHEFAGMCRFESKRFDSRLRKSISEALTRIRGKTITFTRSDSEGLQKVSVTG
                     LLKTGELDFANDQVELEADQRLWELYQTDYTVLLRHKPINALTRKEAAQALYTFIESLP
                     TNPVPISFKRIRDRLSLLSPVKEQNRIIKLALKQLQDIGYLDHSITKKGKETFILIHRR
                     SANLKPGTAV"
                     /name="RepB family plasmid replication initiator protein"
     gene            1527..2153
                     /locus_tag="MKM89_RS27525"
                     /old_locus_tag="MKM89_27520"
     CDS             1527..2153
                     /locus_tag="MKM89_RS27525"
                     /old_locus_tag="MKM89_27520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010260829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family plasmid-partitioning AAA ATPase"
                     /protein_id="WP_004098977.1"
                     /translation="MIIVLGSQKGGVGKSTLAVSIAAYLMSLGNRVIIVDADDQKSVLT
                     WYNNRPEDLPHIPVTGATGNIKAMLKEHEKSYDFVIADCAGRDSAEMRSGLMAADVFIS
                     PLRPSQMDLDVVPHTCSVFTAAKDFNEDVRGYLVLNMTPTNMFVNEANQAADVLKDYPE
                     MCLASSRVCDRKAHRDAWAESMTIFETQNDKAQQEIESLVKEVIL"
                     /name="ParA family plasmid-partitioning AAA ATPase"
     gene            2150..2452
                     /locus_tag="MKM89_RS27530"
                     /old_locus_tag="MKM89_27525"
     CDS             2150..2452
                     /locus_tag="MKM89_RS27530"
                     /old_locus_tag="MKM89_27525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197636.1"
                     /translation="MRNRANTPSRDEAAFINGGTAGIDNTKVTSERPLAVSKAKPVSIS
                     FFEENLKDIDDLITGEMISGKSRVNRSDVVRAAVEALKSLSKTEISRLIAEAKQR"
                     /name="hypothetical protein"
     gene            2970..>3658
                     /locus_tag="MKM89_RS27535"
                     /old_locus_tag="MKM89_27530"
                     /pseudo=""
     CDS             2970..>3658
                     /locus_tag="MKM89_RS27535"
                     /old_locus_tag="MKM89_27530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611483.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEc52 family transposase"
                     /name="IS3-like element ISEc52 family transposase"
     gene            3808..4512
                     /locus_tag="MKM89_RS27540"
                     /old_locus_tag="MKM89_27535"
     CDS             3808..4512
                     /locus_tag="MKM89_RS27540"
                     /old_locus_tag="MKM89_27535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            4522..4821
                     /locus_tag="MKM89_RS27545"
                     /old_locus_tag="MKM89_27540"
     CDS             4522..4821
                     /locus_tag="MKM89_RS27545"
                     /old_locus_tag="MKM89_27540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_256737713.1"
                     /translation="MRQKAASSLTLQQCPKSLAKQLAPKGIRVNAVAPGPYWTVLQCCG
                     GQPQEKIEKFGANAPLGRPGQPVEIAPLYVTLAAEENSYTSGQVWCSDGGTGTL"
                     /name="SDR family oxidoreductase"
     gene            complement(4917..5561)
                     /locus_tag="MKM89_RS27550"
                     /old_locus_tag="MKM89_27545"
     CDS             complement(4917..5561)
                     /locus_tag="MKM89_RS27550"
                     /old_locus_tag="MKM89_27545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017900990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolone resistance pentapeptide repeat protein
                     QnrB4"
                     /protein_id="WP_017900990.1"
                     /translation="MTLALVGEKIDRNRFTGEKVENSTFFNCDFSGADLSGTEFIGCQF
                     YDRESQKGCNFSRANLKDAIFKSCDLSMADFRNINALGIEIRHCRAQGSDFRGASFMNM
                     ITTRTWFCSAYITNTNLSYANFSKVVLEKCELWENRWMGTQVLGATFSGSDLSGGEFSS
                     FDWRAANVTHCDLTNSELGDLDIRGVDLQGVKLDSYQASLLLERLGIAVMG"
                     /name="quinolone resistance pentapeptide repeat protein
                     QnrB4"
     gene            complement(5644..6633)
                     /gene="pspF"
                     /locus_tag="MKM89_RS27555"
                     /old_locus_tag="MKM89_27550"
     CDS             complement(5644..6633)
                     /gene="pspF"
                     /locus_tag="MKM89_RS27555"
                     /old_locus_tag="MKM89_27550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707212.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein operon transcriptional
                     activator"
                     /protein_id="WP_017900991.1"
                     /translation="MVNFIMAGYKDNLLGEANSFIEVLEQVSRLAPLDKPVLVIGERGT
                     GKELIANRLHYLSTRWQGPFISLNCAALNENLLDSELFGHEAGAFTGAQKRHPGRFERA
                     DGGTLFLDELATAPMLVQEKLLRVIEYGELERVGGSQPLQVNVRLVCATNADLPRMVSE
                     GTFRADLLDRLAFDVVQLPPLRERQSDIMLMAEHFAIQMCREIGLPLFPGFTDEAKETL
                     LHYRWPGNIRELKNVVERSVYRHGTSDYPLNEIVIDPFRRHAAPPLAQETRHTSVTLPL
                     DLREFQQQQEKEFLQTSLQQAKFNQKKAAELLGLTYHQLRALLKKHQI"
                     /name="pspF"
     gene            6789..7457
                     /gene="pspA"
                     /locus_tag="MKM89_RS27560"
                     /old_locus_tag="MKM89_27555"
     CDS             6789..7457
                     /gene="pspA"
                     /locus_tag="MKM89_RS27560"
                     /old_locus_tag="MKM89_27555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspA"
                     /protein_id="WP_003020532.1"
                     /translation="MGIFSRFADIVNANINALLEKAEDPQKLVRLMIQEMEDTLVEVRS
                     NSARALAEKKQLSRRIEQASAQQAEWQEKAELALRKEKEDLARSALIEKQKLTDLIASL
                     EHEVTLVDDTLARMKKEIGELENKLSETRARQQALMLRHQAASSSRDVRRQLDSGKLDE
                     AMARFESFERRIDQMEAEAESHNFGKQKSLDQQFADLKADDEISEQLAQLKAKMQQDKQ
                     "
                     /name="pspA"
     gene            7512..7736
                     /gene="pspB"
                     /locus_tag="MKM89_RS27565"
                     /old_locus_tag="MKM89_27560"
     CDS             7512..7736
                     /gene="pspB"
                     /locus_tag="MKM89_RS27565"
                     /old_locus_tag="MKM89_27560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460647.1"
                     /GO_process="GO:0009271 - phage shock [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspB"
                     /protein_id="WP_004193245.1"
                     /translation="MSALFLAIPLTIFVLFVLPIWLWLHYSNRSSRGELAQSEQQRLVE
                     LNQDAQRMRERIQALEDILDAEHPNWRDR"
                     /name="pspB"
     gene            7736..8095
                     /gene="pspC"
                     /locus_tag="MKM89_RS27570"
                     /old_locus_tag="MKM89_27565"
     CDS             7736..8095
                     /gene="pspC"
                     /locus_tag="MKM89_RS27570"
                     /old_locus_tag="MKM89_27565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspC"
                     /protein_id="WP_004193243.1"
                     /translation="MGGVNLNKKLWRIPQQGMVKGVCAGIAHYLDVPVKLVRILVVLSI
                     FFGLAFFTFVAYIVLTFVLDPMPDNVVSGEQQPSSGELLDAVDRELAASEKRLREMERY
                     VTSDTFTLRSRFRQL"
                     /name="pspC"
     gene            8104..8334
                     /gene="pspD"
                     /locus_tag="MKM89_RS27575"
                     /old_locus_tag="MKM89_27570"
     CDS             8104..8334
                     /gene="pspD"
                     /locus_tag="MKM89_RS27575"
                     /old_locus_tag="MKM89_27570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003833267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspD"
                     /protein_id="WP_004193241.1"
                     /translation="MNNRWQRAGQRVKPGIKIAGKLVLLTALRYGPAGVAGWAVKSVAR
                     RPLKMLLALVLEPLLSRAATKLSKRYSGNQP"
                     /name="pspD"
     gene            complement(8523..>8711)
                     /locus_tag="MKM89_RS27580"
                     /old_locus_tag="MKM89_27575"
                     /pseudo=""
     CDS             complement(8523..>8711)
                     /locus_tag="MKM89_RS27580"
                     /old_locus_tag="MKM89_27575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075350.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /name="LacI family transcriptional regulator"
     gene            complement(8669..9490)
                     /locus_tag="MKM89_RS27585"
                     /old_locus_tag="MKM89_27580"
     CDS             complement(8669..9490)
                     /locus_tag="MKM89_RS27585"
                     /old_locus_tag="MKM89_27580"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_013214003.1"
                     /translation="MDVLRFILRLPFILLRLAARSLVYLFTLLGFLLRPFTGRIRWAVP
                     GWVTFAGNQLARLERGGNRYPKTISALLLLTAAVAAGSYYTWHWYQNKPKPVDVAPLVV
                     QDISASVQRPSAVNYNRDDNSAQIVVVTFSRSAAPVTLIGKPVTAGITLTPAMEGEWQW
                     RNDRKLVFTAKKTFPMGKTYTVDMDAKTLLAPQVALTEKQKTFTTPEFYYRGGRAEFYQ
                     DPQDPMKKHAIIGLTFNAPADVKNLESRLSMTRDGKPVPYTVTVMNCCHLC"
                     /name="hypothetical protein"
     gene            complement(9685..10824)
                     /locus_tag="MKM89_RS27590"
                     /old_locus_tag="MKM89_27585"
     CDS             complement(9685..10824)
                     /locus_tag="MKM89_RS27590"
                     /old_locus_tag="MKM89_27585"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032097955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extended-spectrum class C beta-lactamase DHA-1"
                     /protein_id="WP_004236386.1"
                     /translation="MKKSLSATLISALLAFSAPGFSAADNVAAVVDSTIKPLMAQQDIP
                     GMAVAVSVKGKPYYFNYGFADIQAKQPVTENTLFELGSVSKTFTGVLGAVSVAKKEMAL
                     NDPAAKYQPELALPQWKGITLLDLATYTAGGLPLQVPDAVKSRADLLNFYQQWQPSRKP
                     GDMRLYANSSIGLFGALTANAAGMPYEQLLTARILAPLGLSHTFITVPESAQSQYAYGY
                     KNKKPVRVSPGQLDAESYGVKSASKDMLRWAEMNMEPSRAGNADLEMAMYLAQTRYYKT
                     AAINQGLGWEMYDWPQQKDMIINGVTNEVALQPHPVTDNQVQPYNRASWVHKTGATTGF
                     GAYVAFIPEKQVAIVILANKNYPNTERVKAAQAILSALE"
                     /name="extended-spectrum class C beta-lactamase DHA-1"
     gene            10935..11810
                     /gene="ampR"
                     /locus_tag="MKM89_RS27595"
                     /old_locus_tag="MKM89_27590"
     CDS             10935..11810
                     /gene="ampR"
                     /locus_tag="MKM89_RS27595"
                     /old_locus_tag="MKM89_27590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator AmpR"
                     /protein_id="WP_004193231.1"
                     /translation="MVRRYLPLNPLRAFEAAARHLSFTRAAIELNVTHAAVSQQVRALE
                     EQLGCVLFTRVSRGLVLTHEGEGLLPVLNEAFDRIADTLECFSHGQFRERVKVGAVGTF
                     AAGWLLPRLAGFYDSHPHIDLHISTHNNHVDPAAEGHDYTIRFGNGAWHESDAELIFSA
                     PHAPLCSPAIAEQLQQPDDVHRFTLLRSFRRDEWSRWLDCAGGTPPSPSQPVMVFDTSL
                     AMAEAAQLGAGVAIAPVCMFSRLLQSGALVQPFAAEITLGGYWLTRLQSRTETPAMQQF
                     ARWLLNTAAA"
                     /name="ampR"
     gene            complement(11814..12179)
                     /gene="hypA"
                     /locus_tag="MKM89_RS27600"
                     /old_locus_tag="MKM89_27595"
     CDS             complement(11814..12179)
                     /gene="hypA"
                     /locus_tag="MKM89_RS27600"
                     /old_locus_tag="MKM89_27595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004193196.1"
                     /GO_function="GO:0008901 - ferredoxin hydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="WP_025999322.1"
                     /translation="MTDYDNGGRGKLSKALGAADIIREQAEQHGIARVTDVWLEVGALA
                     DVEESALHFCFDIACRDTVAQGCTLHIDVIPAQAWCWDCSREAEIMQHAGCCPHCGSER
                     LRISEGDDLRVKSLEGE"
                     /name="hypA"
     gene            12072..12407
                     /locus_tag="MKM89_RS27605"
                     /old_locus_tag="MKM89_27600"
     CDS             12072..12407
                     /locus_tag="MKM89_RS27605"
                     /old_locus_tag="MKM89_27600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679428.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMR family transporter"
                     /protein_id="WP_052238321.1"
                     /translation="MRYPRNAVLFSLFADNVRRTEGFTKLAPSAVVIIGYGIAFYFLSL
                     VLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLARSPSWKS
                     LRRPTPW"
                     /name="SMR family transporter"
     gene            12401..13240
                     /gene="sul1"
                     /locus_tag="MKM89_RS27610"
                     /old_locus_tag="MKM89_27605"
     ARG             12402..13237
                     /name="sul1"
                     /gene="sul1"
                     /gene_name="sulfonamide-resistant dihydropteroate synthase
                     Sul1"
                     /tool="amrfinderplus"
                     /drug_class="SULFONAMIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            13368..13868
                     /locus_tag="MKM89_RS27615"
                     /old_locus_tag="MKM89_27610"
     CDS             13368..13868
                     /locus_tag="MKM89_RS27615"
                     /old_locus_tag="MKM89_27610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194535.1"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_000376623.1"
                     /translation="MDSEEPPNVRVACSGDIDEVVRLMHDAAAWMSAKGTPAWDVARID
                     RTFAETFVLRSELLVASCSDGIVGCCTLSAEDPEFWPDALKGEAAYLHKLAVRRTHAGR
                     GVSSALIEACRHAARTQGCAKLRLDCHPNLRGLYERLGFTHVDTFNPGWDPTFIAERLE
                     LEI"
                     /name="GNAT family N-acetyltransferase"
     gene            <14189..14257
                     /locus_tag="MKM89_RS27620"
                     /old_locus_tag="MKM89_27615"
                     /pseudo=""
     CDS             <14189..14257
                     /locus_tag="MKM89_RS27620"
                     /old_locus_tag="MKM89_27615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229646.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /name="EAL domain-containing protein"
     gene            14375..15139
                     /locus_tag="MKM89_RS27625"
                     /old_locus_tag="MKM89_27620"
     CDS             14375..15139
                     /locus_tag="MKM89_RS27625"
                     /old_locus_tag="MKM89_27620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389365.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS6100 family transposase"
                     /protein_id="WP_001389365.1"
                     /translation="MTDFKWRHFQGDVILWAVRWYCRYPISYRDLEEMLAERGISVDHT
                     TIYRWVQCYAPEMEKRLRWFWRRGFDPSWRLDETYVKVRGKWTYLYRAVDKRGDTIDFY
                     LSPTRSAKAAKRFLGKALRGLKHWEKPATLNTDKAPSYGAAITELKREGKLDRETAHRQ
                     VKYLNNVIEADHGKLKILIKPVRGFKSIPTAYATIKGFEVMRALRKGQARPWCLQPGIR
                     GEVRLVERAFGIGPSALTEAMGMLNHHFAAAA"
                     /name="IS6-like element IS6100 family transposase"
     gene            complement(15279..>15344)
                     /locus_tag="MKM89_RS27630"
                     /old_locus_tag="MKM89_27625"
                     /pseudo=""
     CDS             complement(15279..>15344)
                     /locus_tag="MKM89_RS27630"
                     /old_locus_tag="MKM89_27625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229646.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /name="EAL domain-containing protein"
     gene            15400..16614
                     /locus_tag="MKM89_RS27635"
                     /old_locus_tag="MKM89_27630"
     CDS             15400..16614
                     /locus_tag="MKM89_RS27635"
                     /old_locus_tag="MKM89_27630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_143212653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II site-specific deoxyribonuclease"
                     /protein_id="WP_004098817.1"
                     /translation="MLMSVFHNWLLEIACENYFVYIKRLSANDTGATGGHQVGLYIPSG
                     IVEKLFPSINHTRELNPSVFLTAHVSSHDCPDSEARAIYYNSRHFGKTRNEKRITRWGR
                     GSPLQDPENTGALTLLAFKLDEQGGDCKEVNIWVCASTDEEDVIETAIGEVIPGALISG
                     PAGQILGGLSLQQAPVNHKYILPEDWHLRFPSGSEIIQYAASHYVKNSLDPDEQLLDRR
                     RVEYDIFLLVEELHVLDIIRKGFGSVDEFIALANSVSNRRKSRAGKSLELHLEHLFIEH
                     GLRHFATQAITEGNKKPDFLFPSAGAYHDTEFPVENLRMLAVKTTCKDRWRQILNEADK
                     IHQVHLFTLQEGVSLAQYREMRESGVRLVVPSSLHKKYPEAVRAELMTLGAFIAELTGL
                     YADIP"
                     /name="type II site-specific deoxyribonuclease"
     gene            complement(16648..18081)
                     /locus_tag="MKM89_RS27640"
                     /old_locus_tag="MKM89_27635"
     CDS             complement(16648..18081)
                     /locus_tag="MKM89_RS27640"
                     /old_locus_tag="MKM89_27635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="WP_001288432.1"
                     /translation="MSEFELLAQDLLEKAEAEEQLRQENDKKLLGQVLEIYDQKYVAEL
                     LRKVGKNEWSRETLNRWINGKCSPKTLTLAEEELLRKMLPEAPAHHPDYAFRFIDLFAG
                     IGGIRKGFETIGGQCVFTSEWNKEAVRTYKANWFNDAQEHTFNLDIREVTLSDKPEVPE
                     NDAYAYINEHVPDHDVLLAGFPCQPFSLAGVSKKNSLGRAHGFECEAQGTLFFDVARII
                     RAKKPAIFVLENVKNLKSHDKGKTFKVIMDTLDELGYEVADAAEMGKNDPKVIDGKHFL
                     PQHRERIVLVGFRRDLNIHQGFTLRDISRFYPEQRPSFGELLEPVVDSKYILTPKLWEY
                     LYNYAKKHAAKGNGFGFGLVNPENKESIARTLSARYHKDGSEILIDRGWDMATGETDFA
                     NEENQAHRPRRLTPRECARLMGFEKVDGRPFRIPVSDTQSYRQFGNSVVVPVFEAVAKL
                     LEPYILKAVNADSCKVERI"
                     /name="DNA cytosine methyltransferase"
     gene            <18180..18452
                     /locus_tag="MKM89_RS27645"
                     /old_locus_tag="MKM89_27640"
                     /pseudo=""
     CDS             <18180..18452
                     /locus_tag="MKM89_RS27645"
                     /old_locus_tag="MKM89_27640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            complement(18463..18669)
                     /locus_tag="MKM89_RS27650"
                     /old_locus_tag="MKM89_27645"
     CDS             complement(18463..18669)
                     /locus_tag="MKM89_RS27650"
                     /old_locus_tag="MKM89_27645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001749967.1"
                     /translation="MKSVTIEAKTFAEMLGITEGELIFAIKKTGTFKNKTIPQPHEPHK
                     SNNRFLYSDVMRFIESLKDKENR"
                     /name="hypothetical protein"
     gene            complement(18674..19111)
                     /locus_tag="MKM89_RS27655"
                     /old_locus_tag="MKM89_27650"
     CDS             complement(18674..19111)
                     /locus_tag="MKM89_RS27655"
                     /old_locus_tag="MKM89_27650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020325134.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004519 - endonuclease activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="WP_020325134.1"
                     /translation="MFEELLLEGFEAHGFRTIRNKRYTGDGGIDGQVIIGKYRYLIQAK
                     RYRGHIALQHVQEFEKLLKRHNCRGLFCHTGKTGAGSKSVSIASERMEIISGQRLIDLL
                     TPGSSFTIATAPQTMMKRTAATLETSTIVKDAGKENRYHES"
                     /name="restriction endonuclease"
     gene            19211..19915
                     /locus_tag="MKM89_RS27660"
                     /old_locus_tag="MKM89_27655"
     CDS             19211..19915
                     /locus_tag="MKM89_RS27660"
                     /old_locus_tag="MKM89_27655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            20013..21133
                     /locus_tag="MKM89_RS27665"
                     /old_locus_tag="MKM89_27660"
     CDS             join(20013..20271,20271..21133)
                     /locus_tag="MKM89_RS27665"
                     /old_locus_tag="MKM89_27660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611474.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="WP_249108299.1"
                     /translation="MKKRFSDEQIICILREAEAGVPARELCRKHAISDATFYTWRKKYG
                     GMEVPEVKRLKSLEEENARLKKLLAEAMLDKEALQVALGRKLLTTDQKREAVMLMCDAT
                     GLSQRRACRLTGLSLSTCRYEAHRPAADAHLSGRITELALERRRFGYRRIWQLLRREGL
                     HVNHKRVYRLYHLSGLGVKRRRRRKGLATERLPLLRPAAPNLTWSMDFVMDALSTGRRI
                     KCLTCVDDFTKECLTVTVAFGISGVQVTRILDSIALFRGYPATIRTDQGPEFTCRALDQ
                     WAFEHGVELRLIQPGKPTQNGFIESFNGRFRDECLNEHWFSNIVHARKIINDWRQDYNE
                     CRPHSALNYQTPSEFAARWRNGKCEGKQTDLTN"
                     /name="IS3 family transposase"
     gene            <21192..21818
                     /locus_tag="MKM89_RS27670"
                     /old_locus_tag="MKM89_27665"
                     /pseudo=""
     CDS             <21192..21818
                     /locus_tag="MKM89_RS27670"
                     /old_locus_tag="MKM89_27665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008502211.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4113 domain-containing protein"
                     /name="DUF4113 domain-containing protein"
     ARG             complement(4921..5561)
                     /name="qnrB4"
                     /gene="qnrB4"
                     /gene_name="quinolone resistance pentapeptide repeat
                     protein QnrB4"
                     /tool="amrfinderplus"
                     /drug_class="QUINOLONE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(9689..10824)
                     /name="blaDHA-1"
                     /gene="blaDHA-1"
                     /gene_name="extended-spectrum class C beta-lactamase DHA-1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          20..894
                     /name="rep_cluster_1418"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgaatggat ataactatat gaatgagaat gtttatatcg gcgaggttat aggtccagat
       61 tgtgaaagtg ttaacaataa actcaccgtc acaagtaagg ccacagttca gcctgtagcc
      121 ctgatgagat taaatgtttt tgttccttca agcaggcctg caaagggcac cagaacatca
      181 atcgatgcga cctctgttct caaggatctg gaattctcaa ggcgggaggg gtacgacgat
      241 attcgtataa ccggtgaacg gttgagtatg gccatcgact tcaaggtatg ggtcggtatc
      301 atagaagctt tcagtaagta cggtttaaaa accaacagca ttaagcttac ttttcatgag
      361 tttgctggaa tgtgccgctt tgagtctaag agattcgatt cccgtcttag aaaaagtatt
      421 tcagaagctt tgaccaggat acgtggcaag accattacct ttacccgtag cgactcagag
      481 ggccttcaaa aagtttccgt aacaggtttg cttaagacag gtgaactgga ttttgcaaac
      541 gaccaggtgg aacttgaagc tgatcagcga ctatgggaac tctaccaaac tgattacact
      601 gttctgctac gacataaacc gataaacgct ttaacccgaa aggaagcagc tcaggccctg
      661 tatactttca tcgaaagcct gcctacgaac ccagtcccca tatctttcaa acgaatacga
      721 gacaggctct cattgctctc tccggtaaag gaacagaacc gtatcattaa actggccctc
      781 aagcagttgc aggatattgg gtaccttgac cacagcatca ccaaaaaagg taaagagact
      841 ttcattctga tccaccgtcg ctcagcaaat ctgaaaccag gaacagctgt ataaggtgtg
      901 tcaaaacggg aaagcaacgc gattaaggtg tgttgaaacg ggaggtctct tcttaaacat
      961 cttgataggt gtgttgtagg gggaagcctc gccttaaacg tcttaatagg tgtgttgtag
     1021 cgggatgaga acctgttaaa tgtgtgtttt tatctgtata tacttacgca ccttcccact
     1081 tcaacacacc tttttggata gaagtgagaa gctatcccgc ttctcaccac cttttaccaa
     1141 atttgtctca ccgactcccc acttcgacac accgaagatt caaaggcttc ccactacgcc
     1201 ccactttttg cttcacgcgg tcataactgg ttgatactac cctccctaaa ggtagcctgg
     1261 agttgaaagc cgcattatgt ggttctatgg ggatttcgga taaaggcacc actttgccat
     1321 cttgttatcc tgttatcttg ttatcttgtt atcttgttat attgttatcc taacatctta
     1381 ctaatttgtt aagattcaaa gataattcaa ttataaatca tgtagttaac aacttaacaa
     1441 gatattaact taataaaggc attgcaatat tgtcgcctgt ttggcaatat taagttgtta
     1501 acttaacaac ttaatatgag gctatgatga taatagtatt gggtagtcaa aagggtgggg
     1561 ttggtaaaag tacactggcg gtatctatag ctgcgtatct gatgtcactg ggcaatagag
     1621 tgatcattgt cgacgcagat gaccagaaat ctgtattgac ctggtacaac aatcgtcctg
     1681 aagatcttcc ccatattccg gttactggcg caacaggcaa catcaaagcc atgctaaagg
     1741 aacacgagaa atcttatgac tttgtcatcg cagactgtgc tggccgcgac agtgcagaaa
     1801 tgcgtagtgg gttgatggcc gctgacgtat tcatttctcc gttgcggcct tctcagatgg
     1861 acctggatgt agtgcctcat acatgctctg tttttacagc agcaaaagat tttaatgagg
     1921 acgtccgggg atatctcgtt ttaaacatga cgcccacgaa catgtttgtc aatgaagcaa
     1981 atcaggcagc tgacgtactc aaggattatc ctgaaatgtg tctggctagc tcccgagttt
     2041 gtgatcgaaa agcgcatcga gatgcctggg cagaatcaat gacaattttt gaaacgcaaa
     2101 atgacaaagc acaacaagaa atcgaatcgt tagttaaaga ggttattctg tgagaaatag
     2161 agcaaatact ccatctcgtg atgaggcagc gtttattaac ggtggtactg ctggtattga
     2221 taataccaaa gtgacttcag agagaccatt ggctgtaagt aaagcaaaac cagtgagcat
     2281 ttcctttttt gaagaaaact taaaagacat tgatgatctt ataacgggtg aaatgatttc
     2341 aggtaaaagc agagtgaatc gttctgacgt agtcagggca gcggtagagg cactaaaaag
     2401 tttatcaaaa acagagatat ccagattaat cgcagaagcg aaacaacgat aacatcttgt
     2461 tatcttgtta tcttgttatc ttgttatctt gttatcttgt tcagggtggt aacacctttt
     2521 atatcgaggc aacaacttcg cgatagtgaa aatttgcgga tggcctcagt cctatacata
     2581 aggggatata catgaattca aatactacaa tcgccttaca tttttcgctt gcattactat
     2641 ttacgttgct atcagtggct ggtagcaacc atgatttagc aggagttgta tctcaattat
     2701 tccttatttt catggctgca ttttttttct ttagggcaat gagggccttt ctgaacatca
     2761 ttaatgtgat tgatagctgt aaaaggtgag gcaggataag cccccattaa gcttggactg
     2821 tttcccacac aagaactact ttaggttgaa acctggggta ttacccatag ttgacctatg
     2881 tagattggtc tggggcttga agtggtttac tgaatttggc cacctgaaca gaggtgatat
     2941 gctcacctca gaacaacaca ggtgtcataa tgaaaaaaag aaatttcagc gcagagttta
     3001 aacgcgaatc cgctcaactg gtcgttgacc agaactacac cgtggcagat gcagccagcg
     3061 ctatggatgt cggcctttcc acaatgacgc gatgggtgaa acaattacgt gatgaacggc
     3121 agggcaaaac accaaaagcc tcccccatta ccccggaaca aattgaaatc cgtgagctca
     3181 ggaaaaagct acaacgtatt gaaatggaaa atgaaatatt aaaaaaggct accgcgctct
     3241 tgatgtcaga ctccctgaac agttctcgat aatcgggaaa ctcagggcgc gttatcctgt
     3301 ggccactctc tgccatgtgt tcggggttca tcgcagcagc tacaaatact ggaaaaaccg
     3361 tcctgaaaag ccagacggca gacgggctgt attacgcagt caggtacttg aactgcatgg
     3421 catcagccac ggctctgccg gagcaagaag catcgccaca atggcaaccc agagaggcta
     3481 ccagatgggg cgctggcttg ctggcagact catgaaagag ctggggctgg tcagttgcca
     3541 gcagccgact caccggtata agcgtggcgg tcatgagcac gttgctatcc cgaatcatct
     3601 tgagcgacag ttcgccgtaa cggaaccaaa tcaggtgtgg tgcggtgatg tgacctatag
     3661 tgtgcccgga gttcagggcg ggcatggatg cttaaatgaa ccgcgagtct gtctggaata
     3721 ttgaaccggt aactcacgat gagaggcact gttgcaaata gtcggtggtg ataaacttat
     3781 catccccttt tgctgatgga gctgcacatg aacccattca aaggccggca ttttcagcgt
     3841 gacatcattc tgtgggccgt acgctggtac tgcaaatacg gcatcagtta ccgtgagctg
     3901 caggagatgc tggctgaacg cggagtgaat gtcgatcact ccacgattta ccgctgggtt
     3961 cagcgttatg cgcctgaaat ggaaaaacgg ctgcgctggt actggcgtaa cccttccgat
     4021 ctttgcccgt ggcacatgga tgaaacctac gtgaaggtca atggccgctg ggcgtatctg
     4081 taccgggccg tcgacagccg gggccgcact gtcgattttt atctctcctc ccgtcgtaac
     4141 agcaaagctg cataccggtt tctgggtaaa atcctcaaca acgtgaagaa gtggcagatc
     4201 ccgcgattca tcaacacgga taaagcgccc gcctatggtc gcgcgcttgc tctgctcaaa
     4261 cgcgaaggcc ggtgcccgtc tgacgttgaa caccgacaga ttaagtaccg gaacaacgtg
     4321 attgaatgcg atcatggcaa actgaaacgg ataatcggcg ccacgctggg atttaaatcc
     4381 atgaagacgg cttacgccac catcaaaggt attgaggtga tgcgtgcact acgcaaaggc
     4441 caggcctcag cattttatta tggtgatccc ctgggcgaaa tgcgcctggt aagcagagtt
     4501 tttgaaatgt aaggcctttg aataagacaa aaggctgcct catcgctaac tttgcaacag
     4561 tgccctaaat cgctggcgaa gcaactggcc cctaaaggga tccgtgtaaa tgctgtcgcg
     4621 cctgggccgt actggacggt attgcagtgc tgcggcggcc aaccacagga aaaaattgag
     4681 aaatttggtg caaatgcgcc gcttggtcgc cctggccaac cggtagaaat tgctccgctg
     4741 tatgtcactt tagcggctga agagaacagc tatacatccg gtcaggtatg gtgttctgac
     4801 ggggggaccg gaaccctctg acgtttatgc ccccgaagtc gaaacgtctg agggggaaag
     4861 ccagcccgga caatattgta taagggcagg gggcggcata taccgctccc tgaacattaa
     4921 cccatgacag cgataccaag acgttccagg agcaacgatg cctggtagct gtccagtttg
     4981 acgccttgca aatcaacccc gcggatatct aaatcgccca gttccgaatt ggtcaaatca
     5041 cagtgcgtaa cgtttgctgc tcgccagtcg aaggatgaaa actcgccgcc agagaggtct
     5101 gatccactga acgttgcgcc cagcacctga gtacccatcc agcggttttc ccacagctcg
     5161 cacttttcca gtacgacttt tgaaaagttg gcgtagctta agttggtatt ggtgatatag
     5221 gcgctacaaa accaggtgcg ggtggtgatc atattcataa aacttgcgcc gcgaaaatct
     5281 gacccttgtg cccggcagtg gcgaatttcg attcccagcg cattgatatt cctgaaatca
     5341 gccatggaga gatcacaact tttgaaaatg gcatctttca ggttagcgcg actaaaatta
     5401 catcctttct gactttctcg atcataaaac tggcagccaa taaattcagt gccgctaagg
     5461 tcggcacccg aaaaatcaca gttgaaaaat gtgctatttt caactttttc accggtgaac
     5521 ctgtttctgt caattttttc gccaactaac gccagagtca tcatgattaa cctgtttttt
     5581 tatacagtga ttgcaacatg gtaaactgtt ttaactctcg cgtccaacgt ctgcccctgc
     5641 acgctaaatt tggtgtttct tcagtaatgc gcggagttga tggtaggtca gacctaataa
     5701 ttcagcggct tttttctgat taaatttcgc ctgctgtaag ctggtttgca aaaattcctt
     5761 ctcctgctgc tgttggaatt cacgcagatc cagcggtagg gttactgatg tatgtctggt
     5821 ttcttgcgcc agcggcggtg cggcgtgacg cctgaacggg tcaatcacaa tctcattcag
     5881 tgggtaatcg ctggtcccgt gtcggtatac cgaacgctcc acgacgtttt tcagttcacg
     5941 aatattgccc ggccaacggt agtggaggag cgtttctttg gcctcatcgg tgaacccagg
     6001 aaacaacggt aacccgatct cacggcacat ctgaatggca aaatgttcag ccattaacat
     6061 gatatcgctt tgacgttcgc gtaacggggg aagttgcacc acgtcaaagg ccagacgatc
     6121 cagcaggtcg gcgcggaacg tgccttcact caccatgcgt ggcaggtcgg cgttggttgc
     6181 gcaaaccagt cttacattga cctgcagagg ttggctaccg cctacgcgtt ccagctctcc
     6241 gtactcaata acgcgcagca gtttttcctg taccagcatc ggggcggttg ccagttcatc
     6301 aagaaacagt gtgccgccat cggcgcgctc gaaccgacct gggtgacgtt tctgcgcgcc
     6361 ggtaaaggcg cccgcttcgt gcccaaagag ttcggaatca agtaaatttt cgttgagcgc
     6421 ggcgcagtta agtgaaataa acgggccttg ccaacgggtt gagaggtagt gcaggcggtt
     6481 ggcgataagc tctttccctg ttcctcgttc cccaatgacc agcacaggtt tatccagcgg
     6541 cgcgagacga gaaacctgct ccagcacttc aataaagctg ttcgcttcgc ccagcagatt
     6601 atctttgtat cctgccatga tgaaattcac catttgttag tgttattcac caatttaccc
     6661 tatttatccc gacaggtaaa attagttatt ttcaaatatt tcaatgaatt aaaaagttgg
     6721 catgcgaagt gcattagaac agcagcaggg cattgcccga tatcagaaca gtaagtgagg
     6781 attacattat gggtattttt tctcgttttg ccgacatcgt gaacgccaac attaatgcgt
     6841 tgctggaaaa ggctgaagat ccgcagaagc tggtgcggtt gatgatccag gaaatggaag
     6901 acacgctggt tgaggtgcgc tccaactccg cacgcgcgct ggcagaaaag aaacagttat
     6961 cgcgtcgtat tgaacaggcc agcgcccaac aggcagagtg gcaggaaaaa gcagagctgg
     7021 cgctgcgtaa agaaaaagaa gatttggcgc gttctgcgtt aatcgaaaag cagaaactga
     7081 ctgacctgat tgcctccctg gagcatgagg tgacgctggt tgacgatacg ctggcgcgta
     7141 tgaaaaaaga gatcggtgaa ctggaaaaca aactcagtga aacccgtgct cgtcagcagg
     7201 cattgatgtt gcgccatcag gcggcgagtt cttcccgtga tgttcgtcgt caactggaca
     7261 gcggcaaact ggatgaagcg atggctcgct ttgaatcttt tgagcgtcgt atcgatcaaa
     7321 tggaagctga agctgaaagc cataacttcg gtaagcagaa gtctttggat cagcaatttg
     7381 ctgacctgaa agcagatgat gaaatcagcg agcagttggc gcaattgaaa gccaaaatgc
     7441 agcaagacaa gcaataataa tatctggcgg tgcccgaacg cgccgccgct catcacctgt
     7501 aaggagtact catgagcgcg ctatttctgg ccatcccgtt aaccatcttt gtgctgttcg
     7561 tcttaccgat ttggctctgg ctgcattaca gcaatcgttc cagtcgcggc gagctggcgc
     7621 aaagtgaaca acagcgtctg gtagaactta accaggacgc acagcggatg cgtgagcgca
     7681 ttcaagcgct ggaagacatc cttgatgctg aacatccaaa ctggagggac cgctaatggg
     7741 gggcgttaat ctgaataaaa aactgtggcg tataccgcag cagggcatgg tgaaaggggt
     7801 ttgcgcgggt attgcgcatt atctcgatgt tcctgtgaaa ctggtgcgga tcctggtggt
     7861 gctgtccatc ttttttggtc tggccttttt cacctttgtc gcctacatcg tactgacgtt
     7921 tgtgttggat ccgatgccag acaacgtggt ttccggagaa cagcagccat caagcggtga
     7981 gctattggat gctgtcgatc gtgaactggc tgcaagtgaa aagcgtttgc gtgagatgga
     8041 gcgttatgta acgtctgata cttttacatt acgcagccgc ttccgccaat tgtgaggtta
     8101 gaaatgaata atcgctggca acgtgccggg caaagggtta agccgggcat taaaatagca
     8161 ggtaagctgg tgctactgac tgcgctgcgc tatggcccgg ctggggtagc agggtgggcg
     8221 gtgaagtccg tggcccgacg tccgctaaaa atgttgctgg cgttagtatt ggaacctttg
     8281 ttgagccggg cagcgacaaa attgtcgaaa cgctattcag gtaatcaacc ctgatatccg
     8341 aaacaacaaa agcaagcaac atttagtcaa cattccccca gttaatttgc ggcagagtag
     8401 tctcttgtgt catgggatcg ctaccaatag aaatgaaggt gaaagcgaca gactccatta
     8461 tgcaggtatc ggtgtgaatt acgcattcta aaatgcactg gggcattgtt atgccccagt
     8521 ttttatacca gtgagtcggc taacgatatt tgtgtaccca cggtgatatt ttgtaaacct
     8581 ttctcaccgg caatcaggct aaataataaa ttacagcttt gttcgccgag ctgctgggtt
     8641 gggacatcaa tgcctcccgg cacgggcgtc agcataaatg acaacagttc attacagtga
     8701 cggtatacgg caccggcttg ccgtcacggg tcatagacag acgcgattcc agatttttga
     8761 catcagcggg ggcattgaag gtcaggccga taatggcgtg ttttttcatc ggatcttgcg
     8821 gatcctgata gaactccgcc cggccgccgc gataataaaa ctcaggggtg gtaaaggttt
     8881 tttgtttctc tgttaacgcc acctgcggag ccagcagtgt tttggcatcc atatcgacgg
     8941 tgtaggtttt ccccatcggg aaggtttttt tcgccgtgaa taccagctta cggtcattac
     9001 gccactgcca ctcaccttcc attgcggggg tcagggtaat accggcggtg accggtttac
     9061 cgatcagcgt taccggtgcg gcagagcggg agaatgtcac caccacaatc tgcgctgaat
     9121 tatcatcacg gttataatta accgccgaag ggcgctgcac agacgcggaa atatcctgca
     9181 ccaccagcgg cgcaacatcc accggcttcg gtttgttctg ataccagtgc caggtgtaat
     9241 aactgcccgc tgccaccgca gcagtcagta ataataaggc agatatggtt ttcggatagc
     9301 ggttgccccc ccgctccagc cgggcaagct gattaccggc aaaggtcacc cagcccggca
     9361 ccgcccagcg gatccgtccg gtgaacgggc gcagcagaaa acccagcaga gtaaagagat
     9421 aaacaagact gcgagccgcc agacgcagca aaataaaagg taagcggagg ataaaacgca
     9481 gaacgtccat gacaacattt tcctctgtgt gttgagactg acatcagttt gccgcagcac
     9541 acagtgaaat ccggttcagc cggaagctgt cagtgcccga tactctcatc ctccataaaa
     9601 cagcccataa agcaaattat tgcataagga ataatcttaa attacggccc cggcgtatcc
     9661 gcaggggcct gttcaggaaa aaaattattc cagtgcactc aaaatagcct gtgcagcttt
     9721 gactctttcg gtattcgggt agtttttatt cgccagaatc acaatcgcca cctgtttttc
     9781 cggaataaag gcgacatagg cgccgaaacc agttgttgcg cccgttttat gcacccagga
     9841 agcacggtta tacggctgaa cctggttgtc tgttaccgga tgcggctgca atgcgacctc
     9901 gttggtcaca ccgttaatga tcatatcttt ctgctgcggc cagtcataca tttcccagcc
     9961 cagcccctgg ttaatcgcgg cggttttata gtagcgggtc tgggcgagat acattgccat
    10021 ttccagatcc gcattaccgg cccgtgacgg ctccatattc atttccgccc agcgcagcat
    10081 atcttttgag gcggatttca cgccgtaaga ttccgcatca agctgtcccg gcgacacgcg
    10141 gaccggtttt ttgtttttat aaccgtacgc atactggctt tgcgcacttt ccggcacagt
    10201 aataaaggtg tgagataacc ccagcggtgc caggatccgt gcagtcagca actgctcata
    10261 cggcatcccc gccgcgtttg cggtcagagc accaaacagg ccgatactgc tgtttgcata
    10321 cagacgcata tcgcccggtt tccgggacgg ctgccactgc tgatagaaat tcagcagatc
    10381 cgcacggctt tttaccgcat ccggcacctg taacggcagt ccgcctgcgg tataggtagc
    10441 cagatccagc aatgtgatcc ccttccactg cggcagagcc agctccggct ggtattttgc
    10501 cgccggatca ttcagcgcca tctctttttt cgccacagaa accgcaccca gcacacctgt
    10561 gaaagtttta cttacagatc cgagctcaaa tagtgtattt tcagtgaccg gctgttttgc
    10621 ctgaatatcg gcaaaaccat aattgaaata atagggctta ccctttacgg agacggcaac
    10681 cgccatcccg ggaatatcct gctgtgccat cagcggttta atggtgctgt ccaccaccgc
    10741 cgcgacatta tcagcggcag aaaaccccgg ggcggaaaac gccagcagag cggaaatcag
    10801 tgttgcagat aacgattttt tcatcagaat taaccttccg tgtgtgagta acggcggcaa
    10861 gtatcgtcag attcaccgga cagaacaaac ggttatttat aacaagagcc taaagaaaaa
    10921 tttacaggtg gattatggtc agacgttatc tcccccttaa cccgctgcgc gcctttgagg
    10981 ccgccgcccg tcatctcagt tttacccgcg cggcgattga gctgaatgtc acccatgccg
    11041 ccgtcagcca gcaggtcagg gcgctggaag aacaactcgg ctgtgtgctg tttacccgcg
    11101 tctcgcgcgg gctggtgctg acccatgaag gtgagggatt actgccggtg ctcaatgagg
    11161 cgtttgaccg gattgcggat actctggagt gtttttctca cgggcagttc cgtgagcggg
    11221 tgaaagtcgg tgcggtggga acatttgccg caggctggct gctgccgcgt ctggccggat
    11281 tctatgacag ccatccgcat attgatctgc atatctccac ccataacaat catgtggacc
    11341 cggcggcgga agggcatgat tatacgatcc gtttcggtaa cggcgcgtgg catgagtcag
    11401 atgcggaact gattttcagt gcaccacacg ctccgctgtg ctcaccggcc attgcagaac
    11461 agttacagca gccggatgat gttcaccgct ttaccctgct gcgctcattc cgccgggatg
    11521 aatggagccg ctggctggat tgtgcgggcg gcacaccgcc ttccccgtca cagccggtaa
    11581 tggtgttcga tacctcactg gccatggccg aggcggcaca actgggtgcc ggggtagcga
    11641 tcgcaccggt atgtatgttc agccgcctgt tacagtcagg cgcactggta cagccgtttg
    11701 ccgcagaaat caccctcggc ggctactggc tgacgcggtt acagtcccgt acggaaaccc
    11761 cggccatgca gcaattcgcc cgctggctgc tgaatacggc ggcggcgtaa aactcactca
    11821 ccttccaggc tttttacccg caaatcatca ccttcactga tgcgcagccg ttcactgccg
    11881 cagtgcggac agcatccggc gtgctgcatg atttcggcct cacggctgca atcccagcac
    11941 catgcctgtg ccgggataac atcaatatgc agtgtgcagc cctgcgccac ggtatcacgg
    12001 caggcgatat caaaacagaa atgcagtgca ctctcctcaa catccgccag tgcgccgact
    12061 tccagccaga catccgttac ccgcgcaatg ccgtgctgtt cagcctgttc gcggataatg
    12121 tccgccgcac cgagggcttt actaagcttg ccccttccgc cgttgtcata atcggttatg
    12181 gcatcgcatt ttattttctt tctctggttc tgaaatccat ccctgtcggt gttgcttatg
    12241 cagtctggtc gggactcggc gtcgtcataa ttacagccat tgcctggttg cttcatgggc
    12301 aaaagcttga tgcgtggggc tttgtaggta tggggctcat aattgctgcc tttttgctcg
    12361 cccgatcccc atcgtggaag tcgctgcgga ggccgacgcc atggtgacgg tgttcggcat
    12421 tctgaatctc accgaggact ccttcttcga tgagagccgg cggctagacc ccgccggcgc
    12481 tgtcaccgcg gcgatcgaaa tgctgcgagt cggatcagac gtcgtggatg tcggaccggc
    12541 cgccagccat ccggacgcga ggcctgtatc gccggccgat gagatcagac gtattgcgcc
    12601 gctcttagac gccctgtccg atcagatgca ccgtgtttca atcgacagct tccaaccgga
    12661 aacccagcgc tatgcgctca agcgcggcgt gggctacctg aacgatatcc aaggatttcc
    12721 tgaccctgcg ctctatcccg atattgctga ggcggactgc aggctggtgg ttatgcactc
    12781 agcgcagcgg gatggcatcg ccacccgcac cggtcacctt cgacccgaag acgcgctcga
    12841 cgagattgtg cggttcttcg aggcgcgggt ttccgccttg cgacggagcg gggtcgctgc
    12901 cgaccggctc atcctcgatc cggggatggg atttttcttg agccccgcac cggaaacatc
    12961 gctgcacgtg ctgtcgaacc ttcaaaagct gaagtcggcg ttggggcttc cgctattggt
    13021 ctcggtgtcg cggaaatcct tcttgggcgc caccgttggc cttcctgtaa aggatctggg
    13081 tccagcgagc cttgcggcgg aacttcacgc gatcggcaat ggcgctgact acgtccgcac
    13141 ccacgcgcct ggagatctgc gaagcgcaat caccttctcg gaaaccctcg cgaaatttcg
    13201 cagtcgcgac gccagagacc gagggttaga tcatgcctag cattcacctt ccggccgccc
    13261 gctagcggac cctggtcagg ttccgcgaag gtgggcgcag acatgctggg ctcgtcagga
    13321 tcaaactgca ctatgaggcg gcggttcata ccgcgccagg ggagcgaatg gacagcgagg
    13381 agcctccgaa cgttcgggtc gcctgctcgg gtgatatcga cgaggttgtg cggctgatgc
    13441 acgacgctgc ggcgtggatg tccgccaagg gaacgcccgc ctgggacgtc gcgcggatcg
    13501 accggacatt cgcggagacc ttcgtcctga gatccgagct cctagtcgcg agttgcagcg
    13561 acggcatcgt cggctgttgc accttgtcgg ccgaggatcc cgagttctgg cccgacgccc
    13621 tcaaggggga ggccgcatat ctgcacaagc tcgcggtgcg acggacacat gcgggccggg
    13681 gtgtcagctc cgcgctgatc gaggcttgcc gccatgccgc gcgaacgcag gggtgcgcca
    13741 agctgcggct cgactgccac ccgaacctgc gtggcctata cgagcggctc ggattcaccc
    13801 acgtcgacac tttcaatccc ggctgggatc caaccttcat cgcagaacgc ctagaactcg
    13861 aaatctaacg tccgttcggg catcgaggtc catgtcgggg tgggacgggc ccgtggcttc
    13921 aagatcactt gcagtccgac cgcgatgtct tggttgcgcg agaggttgtc gatatcctcc
    13981 acttccatca tcaaccctgg ataatgccgc cgccgtcatc gccgccgacg cccgtgccgg
    14041 gcttttcggg cctgtcaggc ttgctcggcc ttcagcctgc ctgggcgaga tctccggcgg
    14101 acggattaac ggcggagctt cgccgccttt cgtgcgtgtg aaggccgaag atagttctct
    14161 caaaaacatc cgtttatgag agataccaaa tgtcattttc agaagacgac tgcaccagtt
    14221 gattgggcgt aatggctgtt gtgcagccag ctcctgacag ttcaatatca gaagtgatct
    14281 gcaccaatct cgactatgct caatactcgt gtgggctctg ttgcaaaaat cgtgaagctt
    14341 gagcatgctt ggcggagatt ggacggacgg aacgatgacg gatttcaagt ggcgccattt
    14401 ccagggtgat gtgatcctgt gggcggtgcg ctggtattgt cgctatccga tcagctatcg
    14461 cgaccttgag gaaatgctgg cggaacgcgg catttcggtc gaccatacga cgatctatcg
    14521 ctgggtccag tgctacgccc cggagatgga gaagcggctg cgctggttct ggcggcgtgg
    14581 ctttgatccg agctggcgcc tggatgaaac ctacgtcaag gtgcggggca agtggaccta
    14641 cctgtaccgg gcagtcgaca agcggggcga cacgatcgat ttctacctgt cgccgacccg
    14701 cagcgccaag gcagcgaagc ggttcctggg caaggccctg cgaggcctga agcactggga
    14761 aaagcctgcc acgctcaata ccgacaaagc gccgagctat ggtgcagcga tcaccgaatt
    14821 gaagcgcgaa ggaaagctgg accgggagac ggcccaccgg caggtgaagt atctcaataa
    14881 cgtgatcgag gccgatcacg gaaagctcaa gatactgatc aagccggtgc gcggtttcaa
    14941 atcgatcccc acggcctatg ccacgatcaa gggattcgaa gtcatgcgag ccctgcgcaa
    15001 aggacaggct cgcccctggt gcctgcagcc cggcatcagg ggcgaggtgc gccttgtgga
    15061 gagagctttt ggcattgggc cctcggcgct gacggaggcc atgggcatgc tcaaccacca
    15121 tttcgcagca gccgcctgat cggcgcagag cgacagccta cctctgactg ccgccaatct
    15181 ttgcaacaga gcctccgtcg ccatgctcac ctcgctttgg tgcacacgag tattgagcat
    15241 agtcgagatt ggtgcagatc acttctgata ttgaactgtc aggagctggc tgcacaacag
    15301 ccattacgcc caatcaactg gtgcagtcgt cttctgaaaa tgacactgtt tgtatataat
    15361 catgaaaaaa tggtgagtag agtttcaggg taacagggga tgcttatgtc ggttttccac
    15421 aactggctac ttgagatcgc atgtgagaat tacttcgtct acatcaaacg cctttccgcc
    15481 aacgataccg gcgcaacagg tggtcaccag gtagggcttt atatcccttc aggtatcgtt
    15541 gaaaaactct ttccgtctat caaccatacc cgtgaactga acccttcggt ttttctcacc
    15601 gcacatgtgt catcgcatga ttgccctgac agcgaagcca gggcaattta ttataacagc
    15661 cgtcattttg gtaaaacccg gaatgaaaaa aggattaccc gctggggtag aggcagccca
    15721 cttcaggatc ctgaaaatac aggggctctg acgctcctgg ctttcaagct tgatgagcaa
    15781 gggggggact gtaaggaagt aaatatttgg gtatgcgcca gcactgatga agaggacgtc
    15841 attgagaccg ctattggtga agttataccc ggagcgctta tatccggccc cgcaggacag
    15901 attctaggcg gactatctct acagcaagcg ccagtaaatc ataaatatat tctacctgaa
    15961 gactggcacc tgcgctttcc gtcgggaagt gaaattattc agtatgcagc cagccattat
    16021 gtgaaaaatt cccttgatcc ggatgagcaa cttcttgacc gccggcgcgt ggagtacgac
    16081 atatttctat tggttgagga actgcatgtt ctggatatca tccggaaagg atttggctct
    16141 gtggatgaat ttattgcgct ggccaattct gtcagcaatc gccgtaaatc cagagccggg
    16201 aagtcgctgg aactgcacct ggagcatcta ttcattgagc acggcctgcg acactttgcg
    16261 acgcaggcca tcacagaagg taataaaaaa cccgatttcc ttttcccttc cgcaggggct
    16321 taccacgata ctgagtttcc cgtagaaaat ctgcgcatgc tggcagtcaa gactacctgt
    16381 aaggatcgct ggcgtcagat actgaatgag gccgataaaa ttcatcaggt gcatctgttt
    16441 acactccagg agggagtttc tctggctcaa tatcgggaga tgcgggagtc gggtgtcaga
    16501 ttggtcgtgc catcatctct gcacaaaaaa tacccggagg cggtgagagc tgagctaatg
    16561 acgctaggtg cgtttattgc tgagctgaca gggctttacg cagatattcc atagattatc
    16621 tcccggcata aataccggga ggagcgatca gattcgttca accttgcacg aatcggcatt
    16681 aaccgctttc aggatataag gttcaagcag tttggctacg gcttcaaaca cgggcaccac
    16741 tacggagtta ccgaactgcc tgtacgactg agtgtctgac acaggaatgc gaaaaggcct
    16801 gccatctact ttttcaaaac ccataaggcg cgcgcactct cgcggagtca gcctgcgggg
    16861 ccgatgcgcc tgattttctt cgttcgcgaa gtctgtttca cctgtggcca tatcccagcc
    16921 acggtctatc agaatttcag acccgtcttt gtgatagcga gcagaaagcg tacgggcaat
    16981 gctttcttta ttttcaggat taacgaggcc aaaaccgaat ccgttaccct tagctgcgtg
    17041 ctttttggcg tagttataga gatactccca gagtttcggc gtcagtatat atttgctgtc
    17101 aaccacgggt tccagcagtt cgccaaatga cggacgctgt tccggataaa aacgactaat
    17161 atcgcgcagg gtaaagccct ggtgaatgtt cagatcacgg cggaaaccga ccaaaacgat
    17221 acgttctcgg tgctgaggta aaaagtgctt tccgtcgata actttaggat cgtttttgcc
    17281 catctcagct gcatccgcaa cttcatagcc cagttcgtcg agggtatcca tgatgacttt
    17341 aaaggtttta cccttgtcat ggctcttcag gtttttaacg ttttcaagaa caaagatggc
    17401 aggttttttt gcgcggataa tacgcgccac atcgaagaaa agcgttccct gagcctcaca
    17461 ttcgaaacca tgcgcgcgcc cgagcgagtt tttcttgctt acgcccgcaa ggctaaacgg
    17521 ttgacagggg aaacctgcta gaagtacatc atgatccggc acatgctcat taatgtaagc
    17581 ataggcatcg ttttcaggta cttcaggttt atcactgagc gtgacttcac gaatatcgag
    17641 attgaaagtg tgttcctgag catcgttaaa ccagttagct ttatatgtgc gcacagcctc
    17701 tttattccat tcactggtaa aaacgcactg gccaccgatg gtttcgaagc ccttccgtat
    17761 acctccaatc ccagcaaaca ggtcaataaa ccggaaggca tagtcagggt gatgtgcagg
    17821 cgcttccgga agcatttttc gtagaagttc ctcttcggct aacgtcagcg tcttaggtga
    17881 gcacttacca ttaatccagc gattaagagt ctcgcgactc cactcatttt taccaacttt
    17941 tctaagcagt tcagccacgt acttctggtc atagatttcc agcacctgcc cgagcagctt
    18001 tttatcattt tcctgtcgca gttgttcttc cgcttctgct ttctcaagca gatcctgcgc
    18061 cagtaattca aattcagaca tattgcctcc attgggtctt atgggtgaaa ctgtatcact
    18121 catttgaccc agattgaatg tttttatctg gatatttaaa caggtttatt gttaggtaac
    18181 gcacgttggc cacgctggag cgtcttctgg gcctgctgtc ggcctttgag gtcgtggtat
    18241 ggatgacgga tggctggccg ctgtatgaac cccgcctgaa gggaaagctg cacgttatca
    18301 gcaagcgtta cactcagcgc attgagcgac ataacctgaa tctgagacaa catctggcaa
    18361 ggctgggacg gaagtcactg tcgttctcaa aatcggtgga gctgcatgac aaggtcatcg
    18421 ggcattatct gaacataaaa cactatcagt aagttggagt cattaccggt tctctttgtc
    18481 ttttagtgat tctataaacc tcattacgtc tgaatataaa aatctattat ttgatttatg
    18541 tggctcatga ggttgtggga tggtcttgtt tttgaatgtg ccagttttct taatggcaaa
    18601 gattaactca ccttctgtta ttcctaacat ttcagcaaat gtttttgctt ctatagttac
    18661 tgacttcatt taattaactc tcatggtatc gattttcttt accggcatct ttaacaatgg
    18721 tgctcgtttc tagtgttgct gcggtacgct tcatcatcgt ctgcggggcg gttgcgatag
    18781 tgaaggagct gccgggcgtg agcaaatcta tcaggcgctg gccgctgata atctccatcc
    18841 gttcactggc aatactgaca gattttgaac ctgcgccggt tttcccggta tggcaaaaca
    18901 gaccgcgaca gttatgacgt ttaagcaact tctcgaactc ctgtacgtgc tgtaaagcaa
    18961 tatggccgcg atagcgttta gcctgaataa gatagcgata ttttcctatt attacctggc
    19021 cgtcaatgcc tccatcgccg gtatagcgtt tgtttctgat ggttctgaag ccatgcgctt
    19081 caaatccttc cagcaacagt tcttcaaaca caaaaggatc aattttcctc aggtagttaa
    19141 ttttttgggc actgttgcaa atagtcggtg gtgataaact tatcatcccc ttttgctgat
    19201 ggagctgcac atgaacccat tcaaaggccg gcattttcag cgtgacatca ttctgtgggc
    19261 cgtacgctgg tactgcaaat acggcatcag ttaccgtgag ctgcaggaga tgctggctga
    19321 acgcggagtg aatgtcgatc actccacgat ttaccgctgg gttcagcgtt atgcgcctga
    19381 aatggaaaaa cggctgcgct ggtactggcg taacccttcc gatctttgcc cgtggcacat
    19441 ggatgaaacc tacgtgaagg tcaatggccg ctgggcgtat ctgtaccggg ccgtcgacag
    19501 ccggggccgc actgtcgatt tttatctctc ctcccgtcgt aacagcaaag ctgcataccg
    19561 gtttctgggt aaaatcctca acaacgtgaa gaagtggcag atcccgcgat tcatcaacac
    19621 ggataaagcg cccgcctatg gtcgcgcgct tgctctgctc aaacgcgaag gccggtgccc
    19681 gtctgacgtt gaacaccgac agattaagta ccggaacaac gtgattgaat gcgatcatgg
    19741 caaactgaaa cggataatcg gcgccacgct gggatttaaa tccatgaaga cggcttacgc
    19801 caccatcaaa ggtattgagg tgatgcgtgc actacgcaaa ggccaggcct cagcatttta
    19861 ttatggtgat cccctgggcg aaatgcgcct ggtaagcaga gtttttgaaa tgtaaggcct
    19921 ttgaataaga caaaacgctg ctgacctgct ccccgttgat tagtacaccc cgatgttagt
    19981 aatgtcttca taagccacat gaggacatcc ccatgaagaa gcgtttttcc gacgaacaga
    20041 tcatctgtat tctccgcgaa gccgaagctg gggtacccgc ccgtgaactc tgccgcaagc
    20101 atgccatttc cgatgccacg ttttacacct ggcgtaagaa gtatggcggt atggaggtgc
    20161 ctgaagttaa gcgcctgaag tcgcttgagg aagagaacgc cagactcaag aagctgcttg
    20221 ccgaagccat gctggataaa gaggcgcttc aggtggctct tgggcgaaag tactgacgac
    20281 agaccagaag cgggaagccg tgatgctgat gtgtgatgcg accggtctgt cgcaacgtcg
    20341 tgcctgcagg cttacaggtt tatccctgtc gacctgccgc tatgaggctc accgtccggc
    20401 tgctgatgcg catttatcag ggcgcatcac tgagctggca ctggagcgca ggcgttttgg
    20461 ctaccgtcgt atttggcagt tgctgcgccg tgaagggctt catgttaatc ataagcgcgt
    20521 gtaccggctt tatcacctca gtggcctggg cgtaaaacgc agaagacgtc gtaaagggct
    20581 ggcaacagaa cgtctgccgc tgctccgtcc ggcggcgccc aatctgacct ggtcgatgga
    20641 tttcgtcatg gacgcacttt ccaccggtcg caggatcaag tgtcttacct gcgtcgatga
    20701 tttcacaaag gaatgcctga cggtcactgt tgcctttggg atttcaggcg ttcaggtcac
    20761 gcgtattctg gacagcattg cactgtttcg aggctatccg gcgacgataa gaactgacca
    20821 ggggccggag ttcacttgcc gtgcactgga tcaatgggcc tttgagcatg gtgttgagtt
    20881 gcgcttaatc cagccgggca agccaacgca gaacggattt attgagagct ttaacggacg
    20941 atttcgcgat gaatgcctga atgagcactg gttcagcaat atcgttcacg caaggaaaat
    21001 cattaatgac tggcggcagg attataacga gtgtcgtcca cattcagcac tgaattatca
    21061 gacgccatca gagtttgcag cacggtggcg aaatggaaaa tgtgaaggta aacaaaccga
    21121 ccttactaac tgacggttgt atctaactct gggggcaggt cactgcctca tcgctaactt
    21181 tgcaacagtg ccaaaatttt tctgtggtcc ttgagcgaac ggtacgggaa ctgaacgggg
    21241 aaagctgcct ttcgcttgag gaagcccctc cgacgaaaca gcaaattgtc tgcagccgca
    21301 gttttggcgt gaagatcacg gagtacgagt cactccgtca ggctatctgt cagcacgcag
    21361 agcgggcctc tgaaaaactg cgtaaagagc accagtattg ccggcatatt tccgttttca
    21421 tcaaaacgtc tccgttcgcc attaaagagc cttactacgg caacgtggct acggaaaaac
    21481 tgcttacacc cactcaggac accagggaca tcattgcagc cgccacaacg gctctggagc
    21541 gtatctggag ggatgggcac cggtatgcca aagccggagt tatgctgaat gacttcaccg
    21601 gctccggcgt ttcgcagctg cagctgtttg acgaacgccc gccacgccct cacagtgctg
    21661 agctgatgag ggttctggac gggatcaaca actcagggct gtgtaaagta tggtttgccg
    21721 gtagaggaat tgcgccatcc tggcaaatga aacgcgatat gctctcccct gcgtacacca
    21781 ctcgctggag agatatcccc gttgcgagga tcggttaaat tttgcctttc agagagagcc
    21841 agcagtgctc gccgcagccg aacgacaggg cgaagcccgc gagtgagcga ggaagcacca
    21901 ggggagctga agccttttaa agcaccttac gcacttaagt tctatagatt ccataatgag
    21961 ttatccacat atcctttgag tagatccaat aacttaccct tagttatcca aatagatcca
    22021 aactgatccc tttagcggca aaacctttgt ttacgggctt cgtagcgatt tcaggtgtgt
    22081 cgtagtggga aaaaggtgtt ctgaagcggg aaaaaggtgt gtcaaaacgg ggtaagggtg
    22141 ggtagaatcg ggaagaaagg tgtgtcgaaa cgggaaatag ttaatattta ggcacatatc
    22201 gatcatatgc t
//
