LOCUS       NZ_CP091589             7619 bp    DNA     circular CON 17-MAR-2024
DEFINITION  Klebsiella pneumoniae strain Nord5-1_R48 plasmid pR48_6, complete
            sequence.
ACCESSION   NZ_CP091589
VERSION     NZ_CP091589.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN25263166
            Assembly: GCF_021899615.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 7619)
  AUTHORS   Braun,S.D.
  TITLE     project DRESI
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7619)
  AUTHORS   Braun,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JAN-2022) Optical Molecular Diagnostics and System
            Technology, Leibniz Institute of Photonic Technology, Albert
            Einstein Strasse 9, Jena 07745, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: flye v. 2.8.3-b1695
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 75.0x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_021899615.1-RS_2024_03_17
            Annotation Date                   :: 03/17/2024 03:32:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,817
            CDSs (total)                      :: 5,691
            Genes (coding)                    :: 5,523
            CDSs (with protein)               :: 5,523
            Genes (RNA)                       :: 126
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 90
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 168
            CDSs (without protein)            :: 168
            Pseudo Genes (ambiguous residues) :: 0 of 168
            Pseudo Genes (frameshifted)       :: 96 of 168
            Pseudo Genes (incomplete)         :: 70 of 168
            Pseudo Genes (internal stop)      :: 21 of 168
            Pseudo Genes (multiple problems)  :: 17 of 168
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP091589.1.
            Bacteria and source DNA available from Sascha D. Braun.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..7619
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="Nord5-1_R48"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pR48_6"
                     /geo_loc_name="Germany"
                     /collection_date="2018-02-18"
     gene            complement(join(7549..7619,1..1015))
                     /locus_tag="L5467_RS01035"
                     /old_locus_tag="L5467_01035"
     CDS             complement(join(7549..7619,1..1015))
                     /locus_tag="L5467_RS01035"
                     /old_locus_tag="L5467_01035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019405083.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="WP_237437532.1"
                     /translation="MIKEISLKNFKCFNELYLKQLKTLNIIAGKNNYGKTSILDAIFCF
                     YDVKNPAVLLNIQAFRKEMAEINKNKPFWVSYFHDMDTSQKMSIVIRDERSEVTQTYET
                     ETNQRLESSLSLNVDTVLSNQNIPRQTIGSQATVNSLKINVTETPNAKNRVSNKLFSMQ
                     LKEDGVEIKSEIKNERDGINYKFKTATIITTSRKINKEATITNVSSLLTQKRKKDILEN
                     LKKIDDRIVDIAISAIGNNKEIYLDIGFSELNEISMLGEGISRALSFISSVLVQENSII
                     LIDEIENGIHYSVIKDIIKSLISSAKQNNNQIFATTHSQDVIRAINEIDSKNEDIAYIY
                     FKNINPNQASPSRAGLSPGCY"
                     /name="ATP-binding protein"
     gene            complement(1360..1473)
                     /locus_tag="L5467_RS01040"
                     /old_locus_tag="L5467_01040"
                     /pseudo=""
     CDS             complement(1360..1473)
                     /locus_tag="L5467_RS01040"
                     /old_locus_tag="L5467_01040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007772075.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /name="replication initiation protein"
     gene            1889..2080
                     /locus_tag="L5467_RS01045"
                     /old_locus_tag="L5467_01045"
     CDS             1889..2080
                     /locus_tag="L5467_RS01045"
                     /old_locus_tag="L5467_01045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_004187666.1"
                     /translation="MTKQQKTALNMAKFIQNQSLLLLEKLNELDLDVEADLCEKLHDDA
                     EHLFRTLSSRLDALQDGN"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            2080..2481
                     /locus_tag="L5467_RS01050"
                     /old_locus_tag="L5467_01050"
     CDS             2080..2481
                     /locus_tag="L5467_RS01050"
                     /old_locus_tag="L5467_01050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009310048.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_237437531.1"
                     /translation="MARVSISEAARLTGKSRTTLHRLIKAGDLSTCIGERNAKMVDTSE
                     LLRVFGPFEQPKGEHHSGQVSGQRDTASADQSEQVIRHLKQEIEHLNTLLLSKDSHIDS
                     LKQAMLLLENHQAKLTESPAPWWKFWKKS"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(2827..3069)
                     /locus_tag="L5467_RS01055"
                     /old_locus_tag="L5467_01055"
     CDS             complement(2827..3069)
                     /locus_tag="L5467_RS01055"
                     /old_locus_tag="L5467_01055"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_098963735.1"
                     /translation="MHSAEIHTIQPGEVLFPAFFSSENGERGRNLLRGREALPAQPENR
                     FSAPSGIGFVDGRQSRYGKSPDDSPHDSPAIRIVN"
                     /name="hypothetical protein"
     gene            complement(3435..4067)
                     /locus_tag="L5467_RS01060"
                     /old_locus_tag="L5467_01060"
     CDS             complement(3435..4067)
                     /locus_tag="L5467_RS01060"
                     /old_locus_tag="L5467_01060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3226 domain-containing protein"
                     /protein_id="WP_012579086.1"
                     /translation="MKDINNSKKIIFVEGDDDFHFLCNLLEIQGITDVFVEKINGKSKL
                     KQALRAFKNIDSFDEKESIFIILDADTSFSDTERSIIATLRELQISSPSSHNEIAMNGN
                     TKISFFIMPGKDKQGAIEDLIIEHASTRALYEYIIEFFEKIKNNKDDISASDKEYTYPT
                     NEKKAKVQVYLSCNRESDSRIGISMKNGIINTADNCFDEIKDFISKI"
                     /name="DUF3226 domain-containing protein"
     gene            complement(4067..5182)
                     /locus_tag="L5467_RS01065"
                     /old_locus_tag="L5467_01065"
     CDS             complement(4067..5182)
                     /locus_tag="L5467_RS01065"
                     /old_locus_tag="L5467_01065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019405083.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="WP_012579087.1"
                     /translation="MIKEISLKNFKCFNELYLKQLKTLNIIAGKNNYGKTSILDAIFCF
                     YDVKNPAVLLNIQAFRKEMAEINKNKPFWVSYFHDMDTSQKMSIVIRDERSEVTQTYET
                     ETNQRLESSLSLNVDTVLSNQNIPRQTIGSQATVNSLKINVTETPNAKNRVSNKLFSMQ
                     LKEDGVEIKSEIKNERDGINYKFKTATIITTSRKINKEATITNVSSLLTQKRKKDILEN
                     LKKIDDRIVDIAISAIGNNKEIYLDIGFSELNEISMLGEGISRALSFISSVLVQENSII
                     LIDEIENGIHYSVIKDIIKSLISSAKQNNNQIFATTHSQDVIRAINEIDSKNEDIAYIR
                     LGREKNSLKPTAVQFNMDDFSYSVENDWEVR"
                     /name="ATP-binding protein"
     gene            complement(5527..5640)
                     /locus_tag="L5467_RS01070"
                     /old_locus_tag="L5467_01070"
                     /pseudo=""
     CDS             complement(5527..5640)
                     /locus_tag="L5467_RS01070"
                     /old_locus_tag="L5467_01070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007772075.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /name="replication initiation protein"
     gene            6056..6247
                     /locus_tag="L5467_RS01075"
                     /old_locus_tag="L5467_01075"
     CDS             6056..6247
                     /locus_tag="L5467_RS01075"
                     /old_locus_tag="L5467_01075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_004187666.1"
                     /translation="MTKQQKTALNMAKFIQNQSLLLLEKLNELDLDVEADLCEKLHDDA
                     EHLFRTLSSRLDALQDGN"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            6247..6648
                     /locus_tag="L5467_RS01080"
                     /old_locus_tag="L5467_01080"
     CDS             6247..6648
                     /locus_tag="L5467_RS01080"
                     /old_locus_tag="L5467_01080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009310048.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_237437531.1"
                     /translation="MARVSISEAARLTGKSRTTLHRLIKAGDLSTCIGERNAKMVDTSE
                     LLRVFGPFEQPKGEHHSGQVSGQRDTASADQSEQVIRHLKQEIEHLNTLLLSKDSHIDS
                     LKQAMLLLENHQAKLTESPAPWWKFWKKS"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(6994..7236)
                     /locus_tag="L5467_RS01085"
                     /old_locus_tag="L5467_01085"
     CDS             complement(6994..7236)
                     /locus_tag="L5467_RS01085"
                     /old_locus_tag="L5467_01085"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_098963735.1"
                     /translation="MHSAEIHTIQPGEVLFPAFFSSENGERGRNLLRGREALPAQPENR
                     FSAPSGIGFVDGRQSRYGKSPDDSPHDSPAIRIVN"
                     /name="hypothetical protein"
     Typing          complement(1361..1768)
                     /name="ColRNAI_rep_cluster_1987"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.399"
                     /coverage="99.0"
                     /evalue="5.92e-171"
     Typing          complement(5528..5935)
                     /name="ColRNAI_rep_cluster_1987"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.399"
                     /coverage="99.0"
                     /evalue="5.92e-171"
ORIGIN
        1 tataagcgat atcttcattt ttgctatcta tttcgtttat tgctcgtatc acatcttgac
       61 tatgagttgt tgcaaatatt tgattgttgt tttgttttgc agatgaaatt aatgatttta
      121 ttatgtcttt aattactgag taatgtattc cgttctcgat ttcatcaata agaataattg
      181 agttttcctg taccagcact gagctgataa aagataatgc tcgactgata ccctcgccaa
      241 gcattgatat ttcatttagc tcactaaatc caatgtctaa atatatttcc ttattgttac
      301 ctatcgcaga tattgctata tctacaattc tgtcatctat tttttttaag ttttctagta
      361 tgtctttttt ccttttttgt gttagtaggc tagatacatt tgtaattgtt gcctctttgt
      421 ttatctttct ggatgttgtt attattgttg ctgtcttaaa tttataatta atcccatccc
      481 tttcgttttt tatttcggat tttatttcta cgccatcttc tttcaattgc atagagaaaa
      541 gcttattgga aaccctgttt ttcgcattgg gtgtctcggt cacatttatt tttaaagagt
      601 ttactgtggc ctgagaaccg atagtttgac gaggtatgtt ttggttagat agtacggtgt
      661 caacgtttag agacaaactt gattctaatc tctgatttgt ttctgtttca tatgtttgtg
      721 ttacttcaga gcgttcatct cgaatgacta tggacatctt ttgtgatgtg tccatatcat
      781 gaaagtaact aacccaaaat ggcttgtttt tgtttatttc tgccatttct tttctgaatg
      841 cttgaatgtt taacaaaaca gccgggtttt ttacatcata aaaacaaaaa atagcatcca
      901 gtatagatgt tttcccgtag ttgtttttcc cagctatgat atttaaagtc tttaattgct
      961 ttagatatag ctcattgaag catttgaagt tctttaaact tatttccttt atcatgatag
     1021 cctctgttcg tgtttttgtt atatgccata cgatttgtta gtaccttaat aaaatgtaca
     1081 gctttcattg tgattagcta gactttatgt caaagattaa ctttgattgc ttgtgtttta
     1141 atcgattttt tttactttct tcttgagatt atctggcagc agccgtaagc ttccggctgt
     1201 gaacgaaaaa aaccgccttg gcgggcggtt ttttcgaaag gttcagtaga gttggcgctc
     1261 tatgaaccga ggtaactggc ttaaagggag cgcagtcacc aaaactgttc gtttagttta
     1321 gctttaactg gcgtataact tcaagactaa ctccctaaat cagttaccag tggctgctgc
     1381 cagtggcgct ttgtcgtgtc tttccgggtt ggactcaaga cgatagttac cggattaggc
     1441 gcagcagtcg gactgaacgg ggggttcgtg catacagtcc agcttggagc gaactgccta
     1501 cccggaactg agtgtcaggc gtggaatgag acaaacgcgg ccataacagc ggaatgacac
     1561 cggtaaaccg aaaggcagga acaggagagc gcacgaggga gccatcaggg ggaaacgcct
     1621 ggtatcttta tagtcctgtc gggtttcgcc accactgatt tgagcgtcag attccgtgat
     1681 gctcgtcagg ggggcggagc ctatggaaaa acggccgctg tgcggccttt ccttctttcc
     1741 tccatgcgat tactcggttt tctcgagcgt ttctacgcat gctcctgccg ctcgccgcag
     1801 ccgaacggca ggagcgtagc gactgagtga gcgaggaagc ggaaaagagg agatccctac
     1861 actgaccact gacgctctga ggcctcttat gacgaaacaa cagaaaacag cgctgaacat
     1921 ggctaaattc atccagaatc agtctctgct cctgctggag aagcttaacg agcttgatct
     1981 cgatgtcgag gccgaccttt gtgagaaact ccacgatgat gcggagcatc ttttccgtac
     2041 actgtcctcg agactggatg cattacagga tggtaactga tggccagagt gtctattagt
     2101 gaggctgccc gactgacggg taagagtaga acaacactgc acaggttaat taaagcaggt
     2161 gacctgtcca cctgtatcgg tgagcgcaat gcaaaaatgg tagatacttc agagctttta
     2221 cgtgtctttg gcccctttga gcaaccgaag ggtgaacacc attctggaca ggtctctgga
     2281 cagcgtgata cagcctctgc tgaccagagt gaacaggtga tccgtcatct gaaacaggag
     2341 attgaacacc tgaacacctt acttttgtcc aaggattcgc acattgacag cctgaaacag
     2401 gccatgctcc ttcttgaaaa tcaccaggca aaattaactg aatccccggc gccatggtgg
     2461 aaattctgga aaaaatcctg accccgtcat gcttcagttt tcctctccgg ccatcccagg
     2521 gagttcctga accttcccaa aaatcgtcag atctctgaac gctcctcacc actaaaaata
     2581 cccacacccc acgcaaaatt aaaattttgc agattcctta tttacaacaa tgggttaatg
     2641 aaaaataaat gtgcggtgat gtgttacaaa gtgcagatcc aagtcgtgga cgactctatg
     2701 gcgaatcgct gacgaattgc ccacgattca tatgtgaatc acgctttatt atcatattgt
     2761 tatgatgaat cgactcttga ttcaattcat cactttgggt gttttttgct catggtgact
     2821 cttgattcaa ttcacgattc gaatcgccgg tgaatcgtgt ggtgagtcgt ccggcgactt
     2881 gccataacgt gattgccggc cgtcgacgaa cccgattcct gaaggtgctg aaaaccggtt
     2941 ttccggctgc gccggcaacg cttcacggcc acgcaataaa ttgcgtcccc gttcaccgtt
     3001 ttcggaggag aagaacgccg gaaacaggac ttcccctggc tgaatggtgt gaatttccgc
     3061 gctatgcact tgcgcgcata ctcatgcatg ccgtaaaaac agagcctgcg cgtttctggc
     3121 gggttttcgg gtggtttgtt gcctgtttta ccggtttccc gtcagaaacg tcctgagtcc
     3181 gttttagcgg tgcgtacaat tatgatttta tgttaaattg ttttaagtga atagagagaa
     3241 tataacttaa gggagcatct tgtgctgggt cttttacatt agatctgcac aatcattgtt
     3301 ttggcatctg gtgatgtctt taggacgttt gagattgctg ataactaaag tgtatgatgc
     3361 tttctatacg ttatccggcg tttaataaca ccctggtgat aagccagccc gtgaagggct
     3421 ggcttgattt ggatttatat ttttgaaata aaatctttta tttcatcaaa gcaattgtct
     3481 gctgtgttta ttattccatt tttcatggat attcctattc ttgagtcgga ttctctattg
     3541 cagctaagat agacttgtac cttagctttt ttttcgtttg ttggataagt gtactctttg
     3601 tcactcgctg agatgtcatc tttattattt ttaatttttt cgaaaaattc tattatgtat
     3661 tcatataacg ctcgagtgct tgcgtgttca attatcagat cttcaatggc accttgcttg
     3721 tcttttcctg gcattataaa gaaagaaatt tttgtattgc cattcatagc tatctcgtta
     3781 tgcgagctgg gggaggagat ttgtagttct cgcaatgtgg caattattga tctttctgtg
     3841 tcagaaaatg atgtgtcagc atctaatata ataaaaatac tttctttttc atcgaaagaa
     3901 tcaatgtttt tgaatgctct aagtgcttgt tttaattttg attttccatt tattttttcg
     3961 acaaaaacat cggtaatgcc ttgtatttca agtaggttgc atagaaaatg aaaatcatca
     4021 tcaccctcaa cgaaaatgat ctttttgcta ttatttatgt ctttcattat cttacctccc
     4081 agtcgttctc aactgagtag gagaaatcat ccatattgaa ttgtacggct gttggtttta
     4141 gggagttctt ttctcttcct agtctaatat aagcgatatc ttcatttttg ctatctattt
     4201 cgtttattgc tcgtatcaca tcttgactat gagttgttgc aaatatttga ttgttgtttt
     4261 gttttgcaga tgaaattaat gattttatta tgtctttaat tactgagtaa tgtattccgt
     4321 tctcgatttc atcaataaga ataattgagt tttcctgtac cagcactgag ctgataaaag
     4381 ataatgctcg actgataccc tcgccaagca ttgatatttc atttagctca ctaaatccaa
     4441 tgtctaaata tatttcctta ttgttaccta tcgcagatat tgctatatct acaattctgt
     4501 catctatttt ttttaagttt tctagtatgt cttttttcct tttttgtgtt agtaggctag
     4561 atacatttgt aattgttgcc tctttgttta tctttctgga tgttgttatt attgttgctg
     4621 tcttaaattt ataattaatc ccatcccttt cgttttttat ttcggatttt atttctacgc
     4681 catcttcttt caattgcata gagaaaagct tattggaaac cctgtttttc gcattgggtg
     4741 tctcggtcac atttattttt aaagagttta ctgtggcctg agaaccgata gtttgacgag
     4801 gtatgttttg gttagatagt acggtgtcaa cgtttagaga caaacttgat tctaatctct
     4861 gatttgtttc tgtttcatat gtttgtgtta cttcagagcg ttcatctcga atgactatgg
     4921 acatcttttg tgatgtgtcc atatcatgaa agtaactaac ccaaaatggc ttgtttttgt
     4981 ttatttctgc catttctttt ctgaatgctt gaatgtttaa caaaacagcc gggtttttta
     5041 catcataaaa acaaaaaata gcatccagta tagatgtttt cccgtagttg tttttcccag
     5101 ctatgatatt taaagtcttt aattgcttta gatatagctc attgaagcat ttgaagttct
     5161 ttaaacttat ttcctttatc atgatagcct ctgttcgtgt ttttgttata tgccatacga
     5221 tttgttagta ccttaataaa atgtacagct ttcattgtga ttagctagac tttatgtcaa
     5281 agattaactt tgattgcttg tgttttaatc gatttttttt actttcttct tgagattatc
     5341 tggcagcagc cgtaagcttc cggctgtgaa cgaaaaaaac cgccttggcg ggcggttttt
     5401 tcgaaaggtt cagtagagtt ggcgctctat gaaccgaggt aactggctta aagggagcgc
     5461 agtcaccaaa actgttcgtt tagtttagct ttaactggcg tataacttca agactaactc
     5521 cctaaatcag ttaccagtgg ctgctgccag tggcgctttg tcgtgtcttt ccgggttgga
     5581 ctcaagacga tagttaccgg attaggcgca gcagtcggac tgaacggggg gttcgtgcat
     5641 acagtccagc ttggagcgaa ctgcctaccc ggaactgagt gtcaggcgtg gaatgagaca
     5701 aacgcggcca taacagcgga atgacaccgg taaaccgaaa ggcaggaaca ggagagcgca
     5761 cgagggagcc atcaggggga aacgcctggt atctttatag tcctgtcggg tttcgccacc
     5821 actgatttga gcgtcagatt ccgtgatgct cgtcaggggg gcggagccta tggaaaaacg
     5881 gccgctgtgc ggcctttcct tctttcctcc atgcgattac tcggttttct cgagcgtttc
     5941 tacgcatgct cctgccgctc gccgcagccg aacggcagga gcgtagcgac tgagtgagcg
     6001 aggaagcgga aaagaggaga tccctacact gaccactgac gctctgaggc ctcttatgac
     6061 gaaacaacag aaaacagcgc tgaacatggc taaattcatc cagaatcagt ctctgctcct
     6121 gctggagaag cttaacgagc ttgatctcga tgtcgaggcc gacctttgtg agaaactcca
     6181 cgatgatgcg gagcatcttt tccgtacact gtcctcgaga ctggatgcat tacaggatgg
     6241 taactgatgg ccagagtgtc tattagtgag gctgcccgac tgacgggtaa gagtagaaca
     6301 acactgcaca ggttaattaa agcaggtgac ctgtccacct gtatcggtga gcgcaatgca
     6361 aaaatggtag atacttcaga gcttttacgt gtctttggcc cctttgagca accgaagggt
     6421 gaacaccatt ctggacaggt ctctggacag cgtgatacag cctctgctga ccagagtgaa
     6481 caggtgatcc gtcatctgaa acaggagatt gaacacctga acaccttact tttgtccaag
     6541 gattcgcaca ttgacagcct gaaacaggcc atgctccttc ttgaaaatca ccaggcaaaa
     6601 ttaactgaat ccccggcgcc atggtggaaa ttctggaaaa aatcctgacc ccgtcatgct
     6661 tcagttttcc tctccggcca tcccagggag ttcctgaacc ttcccaaaaa tcgtcagatc
     6721 tctgaacgct cctcaccact aaaaataccc acaccccacg caaaattaaa attttgcaga
     6781 ttccttattt acaacaatgg gttaatgaaa aataaatgtg cggtgatgtg ttacaaagtg
     6841 cagatccaag tcgtggacga ctctatggcg aatcgctgac gaattgccca cgattcatat
     6901 gtgaatcacg ctttattatc atattgttat gatgaatcga ctcttgattc aattcatcac
     6961 tttgggtgtt ttttgctcat ggtgactctt gattcaattc acgattcgaa tcgccggtga
     7021 atcgtgtggt gagtcgtccg gcgacttgcc ataacgtgat tgccggccgt cgacgaaccc
     7081 gattcctgaa ggtgctgaaa accggttttc cggctgcgcc ggcaacgctt cacggccacg
     7141 caataaattg cgtccccgtt caccgttttc ggaggagaag aacgccggaa acaggacttc
     7201 ccctggctga atggtgtgaa tttccgcgct atgcacttgc gcgcatactc atgcatgccg
     7261 taaaaacaga gcctgcgcgt ttctggcggg ttttcgggtg gtttgttgcc tgttttaccg
     7321 gtttcccgtc agaaacgtcc tgagtccgtt ttagcggtgc gtacaattat gattttatgt
     7381 taaattgttt taagtgaata gagagaatat aacttaaggg agcatcttgt gctgggtctt
     7441 ttacattaga tctgcacaat cattgttttg gcatctggtg atgtctttag gacgtttgag
     7501 attgctgata actaaagtgt atgatgcttt ctatacgtta tccggcgttt aataacaccc
     7561 tggtgataag ccagcccgtg aagggctggc ttgatttgga tttatatttt tgaaataaa
//
