LOCUS       NZ_CP091568             7942 bp    DNA     circular CON 10-JUN-2024
DEFINITION  Salmonella enterica strain 137 plasmid p137-3, complete sequence.
ACCESSION   NZ_CP091568
VERSION     NZ_CP091568.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN16419718
            Assembly: GCF_023330865.1
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica
  ORGANISM  Salmonella enterica
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7942)
  AUTHORS   Ruan,Z.
  TITLE     Genome sequence of Salmonella carrying the mcr gene in China
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7942)
  AUTHORS   Ruan,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2022) Department of Clinical laboratory, Sir Run
            Run Shaw Hospital, School of Medicine, Zhejiang University, 3
            Qingchun East Road, Hangzhou, Zhejiang 310016, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100X
            Sequencing Technology :: Oxford Nanopore GridION; Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023330865.1-RS_2024_06_10
            Annotation Date                   :: 06/10/2024 04:26:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,934
            CDSs (total)                      :: 4,811
            Genes (coding)                    :: 4,699
            CDSs (with protein)               :: 4,699
            Genes (RNA)                       :: 123
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 15
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 34 of 112
            Pseudo Genes (incomplete)         :: 91 of 112
            Pseudo Genes (internal stop)      :: 18 of 112
            Pseudo Genes (multiple problems)  :: 28 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP091568.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..7942
                     /organism="Salmonella enterica"
                     /mol_type="genomic DNA"
                     /strain="137"
                     /isolation_source="stool"
                     /host="Homo sapiens"
                     /db_xref="taxon:28901"
                     /plasmid="p137-3"
                     /geo_loc_name="China: Hangzhou"
                     /collection_date="2017-04-08"
                     /collected_by="Meina Yue"
     ARG             complement(4..602)
                     /name="sul2"
                     /gene="sul2"
                     /gene_name="sulfonamide resistant sul"
                     /tool="rgi"
                     /drug_class="sulfonamide antibiotic"
                     /identity="99.5"
                     /coverage="73.8"
     ARG             complement(7730..7941)
                     /name="sul2"
                     /gene="sul2"
                     /gene_name="sulfonamide resistant sul"
                     /tool="rgi"
                     /drug_class="sulfonamide antibiotic"
                     /identity="100.0"
                     /coverage="25.83"
     gene            complement(910..1761)
                     /gene="repC"
                     /locus_tag="INN76_RS24585"
                     /old_locus_tag="INN76_24575"
     CDS             complement(910..1761)
                     /gene="repC"
                     /locus_tag="INN76_RS24585"
                     /old_locus_tag="INN76_24575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein C, IncQ-type"
                     /protein_id="WP_000240536.1"
                     /translation="MVKPKNKHSLSHVRHDPAHCLAPGLFRALKRGERKRSKLDVTYDY
                     GDGKRIEFSGPEPLGADDLRILQGLVAMAGPNGLVLGPEPKTEGGRQLRLFLEPKWEAV
                     TADAMVVKGSYRALAKEIGAEVDSGGALKHIQDCIERLWKVSIIAQNGRKRQGFRLLSE
                     YASDEADGRLYVALNPLIAQAVMGGGQHVRISMDEVRALDSETARLLHQRLCGWIDPGK
                     TGKASIDTLCGYVWPSEASGSTMRKRRQRVREALPELVALGWTVTEFAAGKYDITRPKA
                     AG"
                     /name="repC"
     gene            complement(1748..>2467)
                     /locus_tag="INN76_RS24590"
                     /old_locus_tag="INN76_24580"
                     /pseudo=""
     CDS             complement(1748..>2467)
                     /locus_tag="INN76_RS24590"
                     /old_locus_tag="INN76_24580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001517559.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="helicase RepA family protein"
                     /name="helicase RepA family protein"
     gene            complement(2517..3221)
                     /locus_tag="INN76_RS24595"
                     /old_locus_tag="INN76_24585"
     CDS             complement(2517..3221)
                     /locus_tag="INN76_RS24595"
                     /old_locus_tag="INN76_24585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            <3285..3623
                     /locus_tag="INN76_RS24600"
                     /old_locus_tag="INN76_24590"
                     /pseudo=""
     CDS             <3285..3623
                     /locus_tag="INN76_RS24600"
                     /old_locus_tag="INN76_24590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /name="recombinase family protein"
     gene            3806..4666
                     /locus_tag="INN76_RS24605"
                     /old_locus_tag="INN76_24595"
     CDS             3806..4666
                     /locus_tag="INN76_RS24605"
                     /old_locus_tag="INN76_24595"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="broad-spectrum class A beta-lactamase TEM-1"
                     /protein_id="WP_000027057.1"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
                     /name="broad-spectrum class A beta-lactamase TEM-1"
     gene            <4813..>5094
                     /locus_tag="INN76_RS24610"
                     /old_locus_tag="INN76_24600"
                     /pseudo=""
     CDS             <4813..>5094
                     /locus_tag="INN76_RS24610"
                     /old_locus_tag="INN76_24600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120888.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase zinc-binding domain-containing
                     protein"
                     /name="transposase zinc-binding domain-containing protein"
     gene            5264..5968
                     /locus_tag="INN76_RS24615"
                     /old_locus_tag="INN76_24605"
     CDS             5264..5968
                     /locus_tag="INN76_RS24615"
                     /old_locus_tag="INN76_24605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(6029..6865)
                     /locus_tag="INN76_RS24620"
                     /old_locus_tag="INN76_24610"
     CDS             complement(6029..6865)
                     /locus_tag="INN76_RS24620"
                     /old_locus_tag="INN76_24610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /protein_id="WP_000480968.1"
                     /translation="MFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLKP
                     IEDIADELRGADYLVWRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATEIA
                     AELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMMSNA
                     SELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDPRRIA
                     QMADAFSRALDVDPRRLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQTSY"
                     /name="aminoglycoside O-phosphotransferase APH(6)-Id"
     gene            complement(6865..7668)
                     /gene="aph(3'')-Ib"
                     /locus_tag="INN76_RS24625"
                     /old_locus_tag="INN76_24615"
     ARG             complement(6869..7668)
                     /name="aph(3'')-Ib"
                     /gene="aph(3'')-Ib"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3'')-Ib"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(6033..6865)
                     /name="aph(6)-Id"
                     /gene="aph(6)-Id"
                     /gene_name="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             3807..4663
                     /name="blaTEM-1"
                     /gene="blaTEM-1"
                     /gene_name="broad-spectrum class A beta-lactamase TEM-1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          1743..2626
                     /name="IncQ1"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 cgcagccgca attcatcgaa ccgcgccagc accgagagcg aggtttcggg agcagccccc
       61 agaaaaaacc ccatgccggg atcaaggaca aggcggttgc gtttgatacc ggcacccgtc
      121 agcgccgcga tgcgcgcgtc aaagaacgcc gcaatgtgat ccatgatgtc gccagcgggt
      181 gcctcgcgcc gatctgcctg cccgtcttgc accgaatgca taacgacgag tttggcagat
      241 gatttcgcca attgcggata gaacgcagcg tctggaaaac cgcgaatatc attgagatag
      301 gccacaccac gcgacaaggc ataggcttgc gtcgcgggtt gataactgtc gagcgagacg
      361 ggaatgccat ctgccttgag cgcgtccagc accggcgcga tacgctcgat ttctgtgtcg
      421 gacgaaacag gcgcggcgtc ggggttgctg gatgccggac cgaggtcgat cacatctgcc
      481 ccctcggcca tcagcttacg cgcctgcgca atggctgcgt ctggcgccag ataccggcct
      541 ccatcggaga aactgtccga ggttatgttg acgatgccga aaatgatgag cgatttattc
      601 atgggggctt ctataataat aataatcgag catgagtctc atacggatgc tcgggtcgaa
      661 agggaatccc caggcgagta acctgtttgc ggtgatccat tagctgcagg agcagaatag
      721 catacatctg gaagcaaagc caggaaagcg gcctatggag ctgtgcggca gcgctcagta
      781 ggcaattttt caaaatattg ttaagccttt tctgagcatg gtatttttca tggtattacc
      841 aattagcagg aaaataagcc attgaatata aaagataaaa atgtcttgtt tacaatagag
      901 tggggggggt cagcctgccg ccttgggccg ggtgatgtcg tacttgcccg ccgcgaactc
      961 ggttaccgtc cagcccagcg cgaccagctc cggcaacgcc tcgcgcaccc gctggcggcg
     1021 cttgcgcatg gtcgaaccac tggcctctga cggccagaca tagccgcaca aggtatctat
     1081 ggaagccttg ccggttttgc cggggtcgat ccagccacac agccgctggt gcagcaggcg
     1141 ggcggtttcg ctgtccagcg cccgcacctc gtccatgctg atgcgcacat gctggccgcc
     1201 acccatgacg gcctgcgcga tcaaggggtt cagggccacg tacaggcgcc cgtccgcctc
     1261 gtcgctggcg tactccgaca gcagccgaaa cccctgccgc ttgcggccat tctgggcgat
     1321 gatggatacc ttccaaaggc gctcgatgca gtcctgtatg tgcttgagcg ccccaccact
     1381 atcgacctct gccccgattt cctttgccag cgcccgatag ctacctttga ccaccatggc
     1441 atcagcggtg acggcctccc acttgggttc caggaacagc cggagctgcc gtccgccttc
     1501 ggtcttgggt tccgggccaa gcactaggcc attaggccca gccatggcca ccagcccttg
     1561 caggatgcgc agatcatcag cgcccagcgg ctccgggccg ctgaactcga tccgcttgcc
     1621 gtcgccgtag tcatacgtca cgtccagctt gctgcgcttg cgctcgcccc gcttgagggc
     1681 acggaacagg ccgggggcca gacagtgcgc cgggtcgtgc cggacgtggc tgaggctgtg
     1741 cttgttctta ggcttcacca cggggcaccc ccttgctctt gcgctgcctc tccagcacgg
     1801 cgggcttgag caccccgccg tcatgccgcc tgaaccaccg atcagcgaac ggtgcgccat
     1861 agttggcctt gctcacaccg aagcggacga agaaccggcg ctggtcgtcg tccacacccc
     1921 attcctcggc ctcggcgctg gtcatgctcg acaggtagga ctgccagcgg atgttatcga
     1981 ccagtaccga gctgccccgg ctggcctgct gctggtcgcc tgcgcccatc atggccgcgc
     2041 ccttgctggc atggtgcagg aacacgatag agcacccggt atcggcggcg atggcctcca
     2101 tgcgaccgat gacctgggcc atggggccgc tggcgttttc ttcctcgatg tggaaccggc
     2161 gcagcgtgtc cagcaccatc aggcggcggc cctcggcggc gcgcttgagg ccgtcgaacc
     2221 actccggggc catgatgttg ggcaggctgc cgatcagcgg ctggatcagc aggccgtcag
     2281 ccacggcttg ccgttcctcg gcgctgaggt gcgccccaag ggcgtgcagg cggtgatgaa
     2341 tggcggtggg cgggtcttcg gcgggcaggt agatcaccgg gccggtgggc agttcgccca
     2401 cctccagcag atccggcccg cctgcaatct gtgcggccag ttgcagggcc agcatggatt
     2461 taccggcact gttgcaaagt tagcgatgag gcagcctttt gtcttattca aaggccttac
     2521 atttcaaaaa ctctgcttac caggcgcatt tcgcccaggg gatcaccata ataaaatgct
     2581 gaggcctggc ctttgcgtag tgcacgcatc acctcaatac ctttgatggt ggcgtaagcc
     2641 gtcttcatgg atttaaatcc cagcgtggcg ccgattatcc gtttcagttt gccatgatcg
     2701 cattcaatca cgttgttccg gtacttaatc tgtcggtgtt caacgtcaga cgggcaccgg
     2761 ccttcgcgtt tgagcagagc aagcgcgcga ccataggcgg gcgctttatc cgtgttgatg
     2821 aatcgcggga tctgccactt cttcacgttg ttgaggattt tacccagaaa ccggtatgca
     2881 gctttgctgt tacgacggga ggagagataa aaatcgacag tgcggccccg gctgtcgacg
     2941 gcccggtaca gatacgccca gcggccattg accttcacgt aggtttcatc catgtgccac
     3001 gggcaaagat cggaagggtt acgccagtac cagcgcagcc gtttttccat ttcaggcgca
     3061 taacgctgaa cccagcggta aatcgtggag tgatcgacat tcactccgcg ttcagccagc
     3121 atctcctgca gctcacggta actgatgccg tatttgcagt accagcgtac ggcccacaga
     3181 atgatgtcac gctgaaaatg ccggcctttg aatgggttca tgtgcagctc catcagcaaa
     3241 aggggatgat aagtttatca ccaccgacta tttgcaacag tgccgccgat atgatccaac
     3301 tgataaagga atttgacgct cagggcgtgg cagtccggtt cattgatgac gggatcagta
     3361 ccgacggtga tatggggcaa atggtggtca ccatcctgtc ggctgtggca caggctgaac
     3421 gccggaggat cctagaacgc acgaatgagg gccgacagga agcaaagctg aaaggaatca
     3481 aatttggccg caggcgtacc gtggacagga acgtcgtgct gacgcttcat cagaagggca
     3541 ctggtgcaac ggaaattgct catcagctca gtattgcccg ctccacggtt tataaaattc
     3601 ttgaagacga aagggcctcg tgatacgcct atttttatag gttaatgtca tgataataat
     3661 ggtttcttag acgtcaggtg gcacttttcg gggaaatgtg cgcggaaccc ctatttgttt
     3721 atttttctaa atacattcaa atatgtatcc gctcatgaga caataaccct ggtaaatgct
     3781 tcaataatat tgaaaaagga agagtatgag tattcaacat tttcgtgtcg cccttattcc
     3841 cttttttgcg gcattttgcc ttcctgtttt tgctcaccca gaaacgctgg tgaaagtaaa
     3901 agatgctgaa gatcagttgg gtgcacgagt gggttacatc gaactggatc tcaacagcgg
     3961 taagatcctt gagagttttc gccccgaaga acgttttcca atgatgagca cttttaaagt
     4021 tctgctatgt ggtgcggtat tatcccgtgt tgacgccggg caagagcaac tcggtcgccg
     4081 catacactat tctcagaatg acttggttga gtactcacca gtcacagaaa agcatcttac
     4141 ggatggcatg acagtaagag aattatgcag tgctgccata accatgagtg ataacactgc
     4201 tgccaactta cttctgacaa cgatcggagg accgaaggag ctaaccgctt ttttgcacaa
     4261 catgggggat catgtaactc gccttgatcg ttgggaaccg gagctgaatg aagccatacc
     4321 aaacgacgag cgtgacacca cgatgcctgc agcaatggca acaacgttgc gcaaactatt
     4381 aactggcgaa ctacttactc tagcttcccg gcaacaatta atagactgga tggaggcgga
     4441 taaagttgca ggaccacttc tgcgctcggc ccttccggct ggctggttta ttgctgataa
     4501 atctggagcc ggtgagcgtg ggtctcgcgg tatcattgca gcactggggc cagatggtaa
     4561 gccctcccgt atcgtagtta tctacacgac ggggagtcag gcaactatgg atgaacgaaa
     4621 tagacagatc gctgagatag gtgcctcact gattaagcat tggtaactgt cagaccaagt
     4681 ttactcatat atactttaga ttgatttaaa acttcatttt taatttaaaa ggatctaggt
     4741 gaagatcctt tttgataatc tcatgaccaa aatcccttaa cgtgagtttt cgttccactg
     4801 agcgtcagac cccttatggc agagcaggga aaggaattgc cgggctatgt gcaacgggaa
     4861 tttgaagaat ttctccaatg cgggcggctg gagcatggct ttctacgggt tcgctgcgag
     4921 tcttgccacg ccgagcacct ggtcgctttc agctgtaagc gtcgcggttt ctgcccgagc
     4981 tgtggggcgc ggcggatggc cgaaagtgcc gccttgctgg ttgatgaagt actgcctgaa
     5041 caacccatgc gtcagtgggt gttgagcttc ccgtttcagc tgcgtttcct gtttggggtc
     5101 gtttgcggga aggggcggaa tcctacgcta aggctttggc cagcgatatt ctccggtgag
     5161 attgatgtgt tcccagggga taggagaagt cgcttgatat ggcactgttg caaatagtcg
     5221 gtggtgataa acttatcatc cccttttgct gatggagctg cacatgaacc cattcaaagg
     5281 ccggcatttt cagcgtgaca tcattctgtg ggccgtacgc tggtactgca aatacggcat
     5341 cagttaccgt gagctgcagg agatgctggc tgaacgcgga gtgaatgtcg atcactccac
     5401 gatttaccgc tgggttcagc gttatgcgcc tgaaatggaa aaacggctgc gctggtactg
     5461 gcgtaaccct tccgatcttt gcccgtggca catggatgaa acctacgtga aggtcaatgg
     5521 ccgctgggcg tatctgtacc gggccgtcga cagccggggc cgcactgtcg atttttatct
     5581 ctcctcccgt cgtaacagca aagctgcata ccggtttctg ggtaaaatcc tcaacaacgt
     5641 gaagaagtgg cagatcccgc gattcatcaa cacggataaa gcgcccgcct atggtcgcgc
     5701 gcttgctctg ctcaaacgcg aaggccggtg cccgtctgac gttgaacacc gacagattaa
     5761 gtaccggaac aacgtgattg aatgcgatca tggcaaactg aaacggataa tcggcgccac
     5821 gctgggattt aaatccatga agacggctta cgccaccatc aaaggtattg aggtgatgcg
     5881 tgcactacgc aaaggccagg cctcagcatt ttattatggt gatcccctgg gcgaaatgcg
     5941 cctggtaagc agagtttttg aaatgtaagg cctttgaata agacaaaagg ctgcctcatc
     6001 gctaactttg caacagtgcc cttgatatct agtatgacgt ctgtcgcacc tgcttgatcg
     6061 cggccgcgat agctagatcg cgttgctcct cttctccatc cgcgttccaa gctgcggaaa
     6121 ggcacccata agcgtacgcc tggtcgagca ggcgacgcgg atcgacgtcc agcgcacgag
     6181 agaatgcgtc cgccatctgt gcaatgcgtc taggatcgag acaaaggtcg tctctgtcag
     6241 ccggatcgta gaacatattg gcggcgccaa agcccacttc accgaccaga ccgacgggat
     6301 ctatcaccag ccagccgcga ctggagaaca tgatgttttc atgatgcaga tcgccatgta
     6361 gcccacgcag ttccgaggca ttgctcatca tttgatcggc tataatcgcc gcgtggacgt
     6421 agtcagtttg acaacctgcg ttttgatcat cgcgcgcccg ctgaaacaaa gctgcaaagc
     6481 gatcccggat cgggagaagg gcagaaggca ggggttcctc agatgcggca tacagcttcg
     6541 ccattagttc cgctgcaatt tcggtcgcct ggtagtcgcc gtgctcggca acgatgtgag
     6601 agagcattcg ctccccggca tattcgagca acatcagatt gttctcacga ccgagcaacc
     6661 ggactgctcc cctcccattg cgccatacca gatagtcggc cccgcgcagt tcatcagcaa
     6721 tgtcttctat aggtttcaat cccttgacga ttgcaggagt cccgtctggc aatgaaactt
     6781 tccaaacgag gctggaaaag gtgtccgcaa tgagaacagg ttgcgaaacg tgccaatgag
     6841 caggaaaaac aggcggcatg aacatcaacc ccaagtcaga gggtccaatc gcagatagaa
     6901 ggcaaggcgt tcgcggtcgg gggcttcgat ccccaataca ttgaatagga cagcgaaggc
     6961 gcgctctgct tcatctggcg ctgcccagtt ctcttcggcg ttagcaatca tgagtgccaa
     7021 atcggcatag cgatctgctg ttccgagccg cccaaggtcg atcagacccg tgcattgaag
     7081 agttttaggg tccaccatga agttcggcat gcagggatca ccatggcaaa caaccatatc
     7141 ggtgcgctct tggtcgagcc gcaccggtag ctctcgttcg acacgagcca aaagatcgag
     7201 ctgcggcgta ctcttgtcct cgtccggtaa gaagtcggga ttgacggcat tgcgggacac
     7261 cacatcaacg gcgcgtccga acattcgcga cagcctgcgc tcaaacggac attgatcaac
     7321 cgataggctg tgaacagcgc caagttgctg ccccattgac ggccacgctt tgagcaaatc
     7381 cgctccagac agatcagccg ccggtactcc cggaattgcc gttatcacca agcatgcacc
     7441 ctcctgttcc tcctgccagt tgatgacctc ggggcaagcc acacctcgac ctttgagcca
     7501 aatgaggcgg tcacgctctc cagcgagctc accgcggcgg gaagcaggtg cgattttcgc
     7561 gaaggcatgc ccgtcaccac gtcgaaaaac aaaatcacca gattctccgc ctctgacagg
     7621 caaccagtca gaatgcgatt caccaaaaaa aatattagtt cgattcaatg gaggttcctt
     7681 cagttttctg atgaagcgcg aatatagaga aatatcccga atgtgcagtt aacgaattct
     7741 tgcggtttct tttagcgccg ccaataccgc cagcccgtcg cgcaaggggc gcggctcgtg
     7801 tgtgcggatg aagtcagctc cacctgcggc ggcggcaagc tctgcagcga gtgtcgcggc
     7861 cccgacatcc cccggaccac ggcctgtgag cgcgcgcaga aaggatttgc gcgaaacaga
     7921 cagaagcacc ggcaaatcga ag
//
