LOCUS       NZ_CP091179            26128 bp    DNA     circular CON 31-JAN-2024
DEFINITION  Aeromonas caviae strain SCLZS52 plasmid pKPC_SCLZS52, complete
            sequence.
ACCESSION   NZ_CP091179
VERSION     NZ_CP091179.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN25038853
            Assembly: GCF_021609985.1
KEYWORDS    RefSeq.
SOURCE      Aeromonas caviae
  ORGANISM  Aeromonas caviae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
            Aeromonadaceae; Aeromonas.
REFERENCE   1  (bases 1 to 26128)
  AUTHORS   Zhang,L. and Li,Y.
  TITLE     To characterize the genomic characterization of Aeromonas caviae
            SCLZS52
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 26128)
  AUTHORS   Zhang,L. and Li,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2022) Department of pathogenic biology, Southwest
            Medical University, No.1 Section 1, Xiang Lin Road, Longmatan
            District, Luzhou, Sichuan 646000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Oxford Nanopore; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/31/2024 05:33:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,727
            CDSs (total)                      :: 4,566
            Genes (coding)                    :: 4,418
            CDSs (with protein)               :: 4,418
            Genes (RNA)                       :: 161
            rRNAs                             :: 11, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 11, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 123
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 148
            CDSs (without protein)            :: 148
            Pseudo Genes (ambiguous residues) :: 0 of 148
            Pseudo Genes (frameshifted)       :: 40 of 148
            Pseudo Genes (incomplete)         :: 111 of 148
            Pseudo Genes (internal stop)      :: 18 of 148
            Pseudo Genes (multiple problems)  :: 19 of 148
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP091179.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..26128
                     /organism="Aeromonas caviae"
                     /mol_type="genomic DNA"
                     /strain="SCLZS52"
                     /isolation_source="wastewater"
                     /db_xref="taxon:648"
                     /plasmid="pKPC_SCLZS52"
                     /geo_loc_name="China:Luzhou"
                     /lat_lon="28.89 N 105.44 E"
                     /collection_date="2019-08"
     gene            join(26045..26128,1..900)
                     /locus_tag="L1871_RS23245"
                     /old_locus_tag="L1871_23240"
     CDS             join(26045..26128,1..900)
                     /locus_tag="L1871_RS23245"
                     /old_locus_tag="L1871_23240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_329611448.1"
                     /translation="MVKSVSQASFLERLPHRPYCTDDPAQGLLIRSQATALAYRHIQHN
                     PPPHVGTLVFDVDRADGYHAWRDANLPAPHWVCVNLRNGHAHLGYQLATPVARTSAAKQ
                     KPLCYLAAIEHVLACRLGADMGYAGLITKNPTHSDWWTVWHPIEPYSLDYLAEFCPDAD
                     LAAYSRRSRKEASGLGRNVTLFDNVREWAYSAVREYWRPNGYDVWAKAVRATCDSANAF
                     GLEQGGPLPPNEIKATAKSIASWVWRHFTPSGFSAIQAVRGAKGGRIGGKVSKGGGRPS
                     NSGKTRADLLPEVLQLKEQGYSNRDIAEDLQISASTVSQYLKRGRE"
                     /name="replication initiation protein"
     gene            complement(1079..1321)
                     /locus_tag="L1871_RS23250"
                     /old_locus_tag="L1871_23245"
     CDS             complement(1079..1321)
                     /locus_tag="L1871_RS23250"
                     /old_locus_tag="L1871_23245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication protein RepB"
                     /protein_id="WP_236277405.1"
                     /translation="MEELQAKWTFDQGGFAKALIAPTPMGAGFHLHLVKFGKQSETVVL
                     ERQRGGWRVFKSIDAAANTANGIGFRRIEIDLSSR"
                     /name="plasmid replication protein RepB"
     gene            complement(1363..1947)
                     /locus_tag="L1871_RS23255"
                     /old_locus_tag="L1871_23250"
     CDS             complement(1363..1947)
                     /locus_tag="L1871_RS23255"
                     /old_locus_tag="L1871_23250"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_236277406.1"
                     /translation="MRPYLFGLLTIVLFGLWWYLDNLLAARGWAMLAANDQWTLVSEGW
                     EILLAAWPLALVGVLVGGIPAFLLVLWVWQYVEEKDHNKEIADLQKELMAAEIRATQAM
                     AEAVAEAKRQTQAEKEEAAQLKQQAIREMDRVKQAAVGLVTMQQQAKLEVVTAQEDVER
                     ANLRARNATATGQRKAKKLATLQAQLAKSSC"
                     /name="hypothetical protein"
     gene            complement(1944..2825)
                     /locus_tag="L1871_RS23260"
                     /old_locus_tag="L1871_23255"
     CDS             complement(1944..2825)
                     /locus_tag="L1871_RS23260"
                     /old_locus_tag="L1871_23255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016947203.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA];
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="WP_236277407.1"
                     /translation="MATFRAPAAQAAKIMQKLQGGVLRSVGTVRNYESALTRVAEWTTS
                     ARISGGLTAITPAIAVQYLEQRGQEVGQKSLDMERQAMQAMMQHVTGQLPTGERLPVIQ
                     SEQAQVLSGRAYTPEQAQRIAAAQSEQHGLATLIAHTAGLRAHELLTLRRGDERAPDPR
                     PALDSKWQGRDGVSYTVQGKGGLVREVRLPHDLAARLEARVLATPQTITDRGIHYQSHY
                     DIGGGQRWSNSVSAASERVLGWSTGAHGLRHSYAQERMNELQYSLNRESALETVSQEMG
                     HFRPEITETYLR"
                     /name="site-specific integrase"
     gene            complement(2832..3062)
                     /locus_tag="L1871_RS23265"
                     /old_locus_tag="L1871_23260"
     CDS             complement(2832..3062)
                     /locus_tag="L1871_RS23265"
                     /old_locus_tag="L1871_23260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005325931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_236277408.1"
                     /translation="MDFNTLTELAALRQQTAAIRKPRHLQSRLDRHRAELLALHQAGAS
                     TAELQRWLRSHRIRVVHSTVARWLTKHSATR"
                     /name="hypothetical protein"
     gene            complement(4207..4587)
                     /locus_tag="L1871_RS23270"
                     /old_locus_tag="L1871_23265"
     CDS             complement(4207..4587)
                     /locus_tag="L1871_RS23270"
                     /old_locus_tag="L1871_23265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011798027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_236277409.1"
                     /translation="MRAYISEKNPGGLLSSNYLKDKYGGEWRYNEIIGFLLFYRYGENK
                     IRCEYWETAAKRKVRTKNKLFIKKSDNYCDELFSTTASSIELATVMKSAVAHCEQRLKG
                     RVLGRQLFDKMVDHIDWIRLFN"
                     /name="hypothetical protein"
     gene            5177..6109
                     /locus_tag="L1871_RS23275"
                     /old_locus_tag="L1871_23270"
     CDS             5177..6109
                     /locus_tag="L1871_RS23275"
                     /old_locus_tag="L1871_23270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005331612.1"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_236277410.1"
                     /translation="MAKAVTWYLKVAERGDSGMKKMMLSPLLAVLLVTSFLPETAKAEV
                     TLGDVSRAEQGDAQAQFKLGLMHYNGEGWPQDFKQAFFWFSKAAEQGNAEAQYNLGIMY
                     DNGEGVPEDNVQAVAWYRQAAEQGQIAAQFKLGMMYYTGQGVAQNYAQAVAWFHKAAEQ
                     GHAVAQTVLGAMYEYGEGVVKDDKQAVAWYRQAAEQGQPGAQSNLGVMYAKGWGVVQDV
                     KQAVAWMRKAAEQGESDAQFNLGLMYVKGQGVPQDYQLAYVWYSVAAANGYKNAVERRD
                     AAAKNLTQADLSTAQQLATSYFDQYRPKP"
                     /name="tetratricopeptide repeat protein"
     gene            complement(6371..9337)
                     /locus_tag="L1871_RS23280"
                     /old_locus_tag="L1871_23275"
     CDS             complement(6371..9337)
                     /locus_tag="L1871_RS23280"
                     /old_locus_tag="L1871_23275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138014.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element TnAs1 family transposase"
                     /protein_id="WP_033991895.1"
                     /translation="MPRRLILSATERGTLLALPESQDDLIRYYTFNDSDLSLIRQRRGD
                     ANRLGFAVQLCLLRYPGYALGTDSELPEPVILWVAKQIQADPTSWAKYGERDVTRREHA
                     LELRTYLQLAPFGLSDFRALVRELTELAQQTDKSLLLAGQALESLRQKRRILPALSVID
                     RACSEAIARANRRVYRALVEPLTDSHRAKLDELLKLKAGSSITWLTWLRQAPLKPNSRH
                     MLEHIERLKTFQLVDLPEVLGRHIHQNRLLKLAREGGQMTPKDLGKFEPQRRYATLAAV
                     VLESTATVIDELVDLHDRILVKLFSGAKHKHQQQFQKQGKAINDKVRLYSKIGQALLEA
                     KEAGSDPYAAIEAVIPWDEFTESVSEAELLARPEGFDHLHLVGENFATLRRYTPALLEV
                     LELRAAPAAQGVLAAVQTLREMNADNLRKVPADAPTAFIKPRWKPLVITPEGLDRRFYE
                     ICALSELKNALRSGDIWVKGSRQFRDFDDYLLLAEKFAALKREQALPLAINPNSDQYLE
                     ERLQLLDEQLATVARLAKDNELPDAILTESGLKITPLDAAVPDRAQALIDQTSQLLPRI
                     KITELLMDVDDWTGFSRHFTHLKDGAEAKDRTLLLSAILGDAINLGLTKMAESSPGLTY
                     AKLSWLQAWHIRDETYSAALAELVNHQYRHAFAAHWGDGTTSSSDGQRFRAGGRGESTG
                     HVNPKYGSEPGRLFYTHISDQYAPFSTRVVNVGVRDSTYVLDGLLYHESDLRIEEHYTD
                     TAGFTDHVFALMHLLGFRFAPRIRDLGETKLYVPQGVQAYPTLRPLIGGTLNIKHVRAH
                     WDDILRLASSIKQGTVTASLMLRKLGSYPRQNGLAVALRELGRIERTLFILDWLQSVEL
                     RRRVHAGLNKGEARNSLARAVFFNRLGEIRDRSFEQQRYRASGLNLVTAAIVLWNTVYL
                     ERATQGLVEAGKPVDGELLQFLSPLGWEHINLTGDYVWRQSRRLEDGKFRPLRMPGKP"
                     /name="Tn3-like element TnAs1 family transposase"
     gene            complement(9341..9901)
                     /locus_tag="L1871_RS23285"
                     /old_locus_tag="L1871_23280"
     CDS             complement(9341..9901)
                     /locus_tag="L1871_RS23285"
                     /old_locus_tag="L1871_23280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220837.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_033943780.1"
                     /translation="MQGHRIGYVRVSSFDQNPERQLEQTKVSKVFTDKASGKDTQRPQL
                     EALLSFVREGDTVVVHSMDRLARNLDDLRRLVQKLTQRGVRIEFLKEGLVFTGEDSPMA
                     NLMLSVMGAFAEFERALIRERQREGITLAKQRGAYRGRKKALSDEQAATLRQRATAGEP
                     KAQLAREFNISRETLYQYLRTDD"
                     /name="recombinase family protein"
     gene            <10293..10910
                     /locus_tag="L1871_RS23290"
                     /old_locus_tag="L1871_23285"
                     /pseudo=""
     CDS             <10293..10910
                     /locus_tag="L1871_RS23290"
                     /old_locus_tag="L1871_23285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017413030.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     gene            11444..11722
                     /locus_tag="L1871_RS23295"
                     /old_locus_tag="L1871_23290"
     CDS             11444..11722
                     /locus_tag="L1871_RS23295"
                     /old_locus_tag="L1871_23290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_013213990.1"
                     /translation="MIHTANRTFHQLYREWIRERREHMHNVLTWERDRYGARLVGLFYR
                     YCKVANPFPRCTLNTRINYRAHAVNLPDWPARSLELNKMWLSWREKK"
                     /name="hypothetical protein"
     gene            11833..12258
                     /locus_tag="L1871_RS23300"
                     /old_locus_tag="L1871_23295"
     CDS             11833..12258
                     /locus_tag="L1871_RS23300"
                     /old_locus_tag="L1871_23295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="WP_013213989.1"
                     /translation="MMQTELNPLICSLVATPRRMAAMPRYVGRFYVVFESMLYQQMKGL
                     CREYRGAYWLMWELSNGGFYMAPGRRDEMLNIEAMNYFSGQMSADAAGITACLYLYSHL
                     SFHTEGADQERFSRLYHSLRDWACEHDEKEAILAAID"
                     /name="antirestriction protein"
     gene            12386..12541
                     /locus_tag="L1871_RS23305"
                     /old_locus_tag="L1871_23300"
     CDS             12386..12541
                     /locus_tag="L1871_RS23305"
                     /old_locus_tag="L1871_23300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_013213988.1"
                     /translation="MNTDIVSLAKHIGDALTARRPVHMPRMKMRELGLLLIELKAYREA
                     AATVTH"
                     /name="hypothetical protein"
     gene            12587..12883
                     /locus_tag="L1871_RS23310"
                     /old_locus_tag="L1871_23305"
     CDS             12587..12883
                     /locus_tag="L1871_RS23310"
                     /old_locus_tag="L1871_23305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="WP_013213987.1"
                     /translation="MIRPETLRPFAEDWQAPTADEIKEVLELIRQRKGLSKPLSGVDVA
                     DLVGLPGERGSGKGTRTFRRWVSKTNPSPIAYGAWSILAHLAGFGAIWDADRD"
                     /name="transcriptional regulator"
     gene            <12987..13868
                     /locus_tag="L1871_RS23315"
                     /old_locus_tag="L1871_23310"
                     /pseudo=""
     CDS             <12987..13868
                     /locus_tag="L1871_RS23315"
                     /old_locus_tag="L1871_23310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152397.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISKpn6 family transposase"
                     /name="IS1182-like element ISKpn6 family transposase"
     gene            complement(14118..14999)
                     /locus_tag="L1871_RS23320"
                     /old_locus_tag="L1871_23315"
     CDS             complement(14118..14999)
                     /locus_tag="L1871_RS23320"
                     /old_locus_tag="L1871_23315"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015256839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbapenem-hydrolyzing class A beta-lactamase
                     KPC-2"
                     /protein_id="WP_004199234.1"
                     /translation="MSLYRRLVLLSCLSWPLAGFSATALTNLVAEPFAKLEQDFGGSIG
                     VYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLARSQQQAGLLDTPIRYGKNALVPW
                     SPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFRLDR
                     WELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQQFVDWLKGNTTGNHRIRA
                     AVPADWAVGDKTGTCGVYGTANDYAVVWPTGRAPIVLAVYTRAPNKDDKHSEAVIAAAA
                     RLALEGLGVNGQ"
                     /name="carbapenem-hydrolyzing class A beta-lactamase KPC-2"
     gene            complement(15221..15823)
                     /gene="bla"
                     /locus_tag="L1871_RS23325"
                     /old_locus_tag="L1871_23320"
     CDS             complement(15221..15823)
                     /gene="bla"
                     /locus_tag="L1871_RS23325"
                     /old_locus_tag="L1871_23320"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015873518.1"
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]; GO:0046677 - response to antibiotic
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase"
                     /protein_id="WP_078207265.1"
                     /translation="MTLINASIILKNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNT
                     AANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRK
                     LLTGELLTLASRQQLIDWMEADKVTGPLLRSALPAGWFIADKSGAGERGSRGIIAALGP
                     DGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW"
                     /name="bla"
     gene            complement(15946..16926)
                     /locus_tag="L1871_RS23330"
                     /old_locus_tag="L1871_23325"
     CDS             complement(15946..16926)
                     /locus_tag="L1871_RS23330"
                     /old_locus_tag="L1871_23325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013213985.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS481-like element ISKpn27 family transposase"
                     /protein_id="WP_013213985.1"
                     /translation="MTQALHSQARTTHLIREEIRNSTLPQAELARMYNVTRQTIRKWQN
                     RESPEDKSHAPNKMYTTLTPEQELIVVELRKTLLLPTDDLLAVTREFINPAVSRAGLGR
                     CLRRHGVSDLRNLVEQEGTAPATKKTFKDYEPGFVHIDIKYLPQMPDETARRYLFVAID
                     RATRWVFIELYADQTDGSSGDFLNKVQQACPVKIVKLLTDNGSQFTDRFTAGGKKKEPS
                     GTHVFDRLCKQLGIEHRLIPPRHPQTNGMVERFNGRISDIVNQTRFGSAAELESTLRNY
                     VKIYNHSIPQRALQHKTPVQALKEWHEKRPELFRKRVYNQPGLDI"
                     /name="IS481-like element ISKpn27 family transposase"
     gene            complement(17049..17606)
                     /locus_tag="L1871_RS23335"
                     /old_locus_tag="L1871_23330"
     CDS             complement(17049..17606)
                     /locus_tag="L1871_RS23335"
                     /old_locus_tag="L1871_23330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001217881.1"
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="recombinase family protein"
     gene            17769..20774
                     /locus_tag="L1871_RS23340"
                     /old_locus_tag="L1871_23335"
     CDS             17769..20774
                     /locus_tag="L1871_RS23340"
                     /old_locus_tag="L1871_23335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /protein_id="WP_001143760.1"
                     /translation="MPVDFLTTEQTESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHEEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISRSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLCENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASELVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQVSVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGTLGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
                     /name="Tn3-like element Tn3 family transposase"
     gene            complement(21081..21320)
                     /locus_tag="L1871_RS23345"
                     /old_locus_tag="L1871_23340"
     CDS             complement(21081..21320)
                     /locus_tag="L1871_RS23345"
                     /old_locus_tag="L1871_23340"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_160838349.1"
                     /translation="MSIKGIPKVRMQAKGLYHSGNVDAAQTLTDMADAYEYLAAEYGRV
                     MVQAGYSASREECKNEALAWLDPTKRPVVEEGGI"
                     /name="hypothetical protein"
     gene            complement(21893..22633)
                     /gene="istB"
                     /locus_tag="L1871_RS23350"
                     /old_locus_tag="L1871_23345"
     CDS             complement(21893..22633)
                     /gene="istB"
                     /locus_tag="L1871_RS23350"
                     /old_locus_tag="L1871_23345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020485619.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="WP_010675356.1"
                     /translation="MSADEIYQRLQGLKLFGMAALCDELLAHRERPLPPPEQWLKRMIE
                     AEESERQCRSIRYQMGIAKFPLARDLDSFETADTPVSPVHLSALDRDDFLEQKRNLLLI
                     GGTGTGKTHLAIALGRNAVRRGKRVRFYGVVDLVNQLEQEKAAGKAGQLANRLVNVDAV
                     ILDELGYLPFAESGGALLFHLISKLYERTSLILTTNLAFSEWSKVFTDEKMTTAMLDRI
                     THHCEIIETGNDSYRFKQRMKSAS"
                     /name="istB"
     gene            complement(22620..24119)
                     /gene="istA"
                     /locus_tag="L1871_RS23355"
                     /old_locus_tag="L1871_23350"
     CDS             complement(22620..24119)
                     /gene="istA"
                     /locus_tag="L1871_RS23355"
                     /old_locus_tag="L1871_23350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012824097.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="WP_010675355.1"
                     /translation="METVLKIRRMHQVDGQSISAIAKVTGLSRNTVRKYLRQPPSEPPK
                     YRRPQPARPKLGEFESTLTQWLDLDAKRPKRQRRCARQLFEDLQRLGYQGAYDSVQRFV
                     RDYKQQSAKVAAFVPLTFAAGEAYQFDWSEEEVEIGGVVQRVKAAHFRLTHSRQPFVMV
                     FPRETQEMVFAAHDAAFHYWGGVPRQGIYDNLKTCIDQVLEGKERRFNPRFLALMSHYV
                     IEPVACTPASGWEKGQVEKQVQDVRRRCFTPRRKVDSLAELNRRLIQELEQAAQTRPHP
                     DDPSQTVWQRFEQERTTLRPLAARFNGYVERELRVDSTCLIHFDRNTYSVDSRYAHRHV
                     TARVFADRLQVYAQSELIAEHPRQFGRDKTQFDPWHYLGLLEHKPGALRHGAPFKEWVL
                     PPALSRLQQQLLSRKGGDRDMVKLLLAARQDGLDLLEQACQQVLLLGGSSAELVLNHLQ
                     RLRRPVEVPQLHAQVVPLAQPPQANCQRYDSLLPGGQHVSR"
                     /name="istA"
     gene            complement(24269..24502)
                     /locus_tag="L1871_RS23360"
                     /old_locus_tag="L1871_23355"
     CDS             complement(24269..24502)
                     /locus_tag="L1871_RS23360"
                     /old_locus_tag="L1871_23355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006924210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_160838347.1"
                     /translation="MSKKVTIGAKPTSKSAQASADEWVENRSTGNAPEPMKRLTIDIPE
                     SLHRAIKMQCASRGAKIADEVRELLLQKYGNL"
                     /name="hypothetical protein"
     gene            complement(24499..25128)
                     /gene="parA"
                     /locus_tag="L1871_RS23365"
                     /old_locus_tag="L1871_23360"
     CDS             complement(24499..25128)
                     /gene="parA"
                     /locus_tag="L1871_RS23365"
                     /old_locus_tag="L1871_23360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017158739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family partition ATPase"
                     /protein_id="WP_068979437.1"
                     /translation="MIIGLLNQKGGVGKTTLSVNLAASLARRGFRVLLIDADPQGSALD
                     WAAARDGEPLFSVVGLPRATVHKEIGQLGQGYDHIVIDGPPRVTDLARSAIMAADVVLI
                     PVQPSPYDIWAADEVVKLIEEARIYKEGLKAAFVVNRKIANTAIGRDVGAALAAYPIPV
                     LTASITQRVVFAEAAAQGRAVHETDETGPAAAEIDAVMAELMEIAR"
                     /name="parA"
     gene            25307..25549
                     /locus_tag="L1871_RS23370"
                     /old_locus_tag="L1871_23365"
     CDS             25307..25549
                     /locus_tag="L1871_RS23370"
                     /old_locus_tag="L1871_23365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016984130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="WP_160838345.1"
                     /translation="MGTINLRIDDDLKARSFAVLDKLGVTPSDILRQTLEYVASQGRSP
                     FRTTVVTEDEEALLAIVRERLASPQKGIKVSLDDL"
                     /name="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
     gene            25539..25826
                     /locus_tag="L1871_RS23375"
                     /old_locus_tag="L1871_23370"
     CDS             25539..25826
                     /locus_tag="L1871_RS23375"
                     /old_locus_tag="L1871_23370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321942.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_160838343.1"
                     /translation="MTFELEFDPRAWKEWKKLGDTVRQQFKKKLSEVIERPRIEANRLN
                     GMPDCYKIKLRGAGYRLVYQVQDDRVVVFVVAVGKREREEVYLDAMSRLD"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     ARG             complement(14122..14999)
                     /name="blaKPC-2"
                     /gene="blaKPC-2"
                     /gene_name="carbapenem-hydrolyzing class A beta-lactamase
                     KPC-2"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(15222..15871)
                     /name="TEM-246"
                     /gene="TEM-246"
                     /gene_name="TEM beta-lactamase"
                     /tool="rgi"
                     /drug_class="monobactam; cephalosporin; penam; penem"
                     /identity="98.95"
                     /coverage="75.52"
     Typing          complement(1080..1258)
                     /name="rep_cluster_2037"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.0"
                     /coverage="95.0"
                     /evalue="4.76e-74"
     Typing          10351..10910
                     /name="IncU"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ttgatccgct cgcaggccac tgcactagcc tatcgccata tccagcacaa tccgccgccg
       61 cacgttggca ccctggtgtt cgatgtcgat cgggccgatg ggtaccacgc ctggcgggat
      121 gccaatcttc ctgctccgca ctgggtctgc gtcaacctgc gcaacggcca tgcccatctg
      181 ggctatcagt tggccacccc cgttgcccgt accagtgccg ccaagcaaaa gcccctgtgc
      241 tatctcgccg ccatcgaaca cgtgctggcg tgtcgactgg gggcggacat ggggtacgca
      301 ggccttatca ccaaaaaccc cacacacagc gattggtgga cggtttggca ccccatcgag
      361 ccgtactccc tcgactatct ggccgagttc tgcccggatg cggatttggc ggcctacagc
      421 cgccgcagtc gcaaagaggc gagcgggctg gggcgtaacg tcaccttgtt cgataacgtg
      481 cgtgaatggg cctatagcgc cgtcagagag tattggcggc ccaatggcta tgacgtctgg
      541 gccaaggccg tccgcgctac ctgtgacagt gccaatgcgt ttgggctgga gcagggcggc
      601 ccgttgccac ccaacgagat caaagccacg gccaagagta ttgccagttg ggtatggcgg
      661 cacttcaccc cgtccggatt cagcgctatc caggcggtca gaggggccaa gggcgggcgc
      721 atcggtggca aggtatccaa gggtgggggc agaccaagca acagcggcaa gacccgtgct
      781 gacctgttgc cggaggtgct gcaactcaag gagcagggct acagtaaccg cgacattgcc
      841 gaggatctgc aaatctcggc cagtaccgtc agtcagtatc tcaaacgtgg gcgcgagtga
      901 tcgaaacaaa gccatatcag ataacagcgc cctttgggcg tcgttgtctg atatggcttt
      961 cccttagaga gaggatcttg gcgaggtggg caagcgcccg caccggaggc cgtccatcag
     1021 gccgtgggtt tggcctgtgg gcgggggcgt tgtccacgga gtggggtggg gttggccctc
     1081 aacgactgga caggtctatc tcgatgcgcc gaaagcctat cccgttggcg gtgttggcgg
     1141 cggcatcgat gctcttgaac acccgccagc caccgcgttg tcgttccagg acaacggtct
     1201 cgctctgttt gccgaacttc accaggtgaa gatggaagcc agcacccatc ggggttgggg
     1261 cgatcagcgc cttggcgaac ccgccctggt caaacgtcca cttcgcttgc agttcttcca
     1321 tatcaaatct cgcctttgag tcatcaaatt aactaaatga ttctagcatg agcttttggc
     1381 aagctgcgcc tgcaacgttg ctaacttttt ggctttgcgc tggccggttg ccgtcgcatt
     1441 gcgtgctcta aggtttgccc gttccacgtc ttcctgggcg gtgaccacct ctaatttggc
     1501 ctgttgctgc atggtgacca ggcctactgc agcctgtttg acccgatcca tctcgcgtat
     1561 tgcctgctgc ttgagttgtg cggcctcttc cttctctgcc tgcgtttgcc gtttagcctc
     1621 ggcaaccgcc tctgccatgg cctgggttgc gcggatctcg gcggccatca actctttctg
     1681 aaggtccgca atctccttgt tgtgatcctt ttcctccacg tactgccata cccagagcac
     1741 caggagaaat gcgggtatgc caccaaccag cacaccgact aatgccagcg gccaagccgc
     1801 cagcaagatc tcccagcctt cactgaccag tgtccactgg tcgttggctg ccagcatggc
     1861 ccagcctcgt gccgccagca ggttatccag ataccaccac agcccgaaca ggacgatggt
     1921 cagcaggcca aacaggtagg gtctcatcgt aggtaggtct ccgtgatctc tggccgaaaa
     1981 tggcccattt cctggctgac agtctcaagg gcgctctccc gattgaggct gtattgcaat
     2041 tcgttcatcc gttcctgggc gtaagagtgg cgcagaccgt gggcgccggt agaccagccc
     2101 agcacccgct cgctggcggc ggagaccgag ttgctccaac gctggccgcc gccgatgtcg
     2161 tagtgggact ggtaatgaat gccgcgatcc gtgattgtct ggggcgtcgc taggacgcga
     2221 gcctccagtc tggcggccag gtcatgcggc agcctcacct ctcgcactag tccgcctttg
     2281 ccctggactg tgtagctcac cccatcacgg ccctgccatt tgctgtccag ggctgggcgg
     2341 ggatcggggg cacgctcatc gccccgacgc agggtcagca gttcgtgggc acgcaggcca
     2401 gcagtgtggg cgatcagggt cgccagcccg tgctgttctg actgggcggc agcaatgcgc
     2461 tgggcctgct cgggggtata ggcccggcca ctgagcactt gggcctgttc ggactggatg
     2521 acgggcagac gctcaccggt gggtagttgg ccagtaacgt gctgcatcat ggcctgcatg
     2581 gcctgccgct ccatgtcgag gctcttctga ccgacctctt ggccacgctg ctccagatac
     2641 tgcactgcga tggctggggt gatggcggtg aggccaccgg agatccgtgc tgaggtcgtc
     2701 cattcggcca cgcgggtgag cgcggactcg tagtttctga ctgtgccgac ggaacgcaac
     2761 acgcccccct gcaacttctg catgatcttg gcggcctggg ccgcaggcgc acgaaaggta
     2821 gccatcagcg atcagcgggt tgctgagtgt ttggtgagcc agcgggccac ggtgctgtgg
     2881 accacccgga tccggtgact gcgcagccag cgttgcagct cggcggtgct agcgccagcc
     2941 tggtgcaggg cgagcagttc ggcacggtgg cgatcaaggc gggattggag atgccgtggt
     3001 ttgcggatcg cggcggtttg ctggcgcagg gcggccagct cggtgagggt gttgaagtcc
     3061 atttgaagct ccacgttaga acgacaacat ccaactggat gtcgcgacag gtattacccc
     3121 gccgatcgcc ccggttctcc aatgtcgttt ggagggctcg gactgttctc gcccatgctc
     3181 gatcctgttt gcgtgcggat aacacgggag ttttggctgt ctccgtcaga acgcgtaagc
     3241 gtctcccatt ttggctgtgg ggttcagtgc tctgccgttt tggctggcct cggataggtt
     3301 acctgtatcc ggtgtagcag ggtcacgttg gagtgcgacg ggctcataag agccataatc
     3361 gtagcctgaa aaaatgtgcc aaatgaatgt gtttttaaaa atgtgcgtga aattgctaca
     3421 agatagagac cacgctatgt agcggcccat ttatgggtcg tacatagcgt ggtcagggaa
     3481 tggcatggag gggaaaccag acgagggcgt gggtagggct ggccagcgcc atcaaaagct
     3541 gaaatagatg aatcaaaaag ccaaaatgat ggcggaattt ccgcaaggca cagtttcaca
     3601 tgtgaaactg tgccttggtt tgaggggggg gcaggcagtg tccggccagg acgcaggccg
     3661 ggggattgtc ctggtaggac atcgagggag gcggcgggga cgatcccaat gttctaccag
     3721 gacaacgagg acacactttc acatgtgaaa gtcgtggccc agtgcaaggg ggccgatttt
     3781 ggcagttcat gacgattttg ggttgaaacc ggatcggctc accgggcggg agattcgccc
     3841 cttcaaaccg tcacaaactt tcagccgcga tccggccaga acgggccggg atgagggggt
     3901 gtttgtcgca ctggcgggct ggaacgggac gagagcgcca ttttcccagg tgaaaatgcc
     3961 aattgaacat aatgggcatt aggcgcactg cctttggctg atgttctgct cacgatgccg
     4021 acatgagcgg cgatttggtg atcgcgtcga gggtttctcc aaaagacacg ctcaggtcca
     4081 atgctatttg ggcaacgcct tgatgaccct aaacggatgc tccactgtca tgccacctgt
     4141 cagtgtttat cacctctaac taggtggcaa aattcactat gccactacaa aagcctttct
     4201 ttgcattcaa ttgaataggc gtatccagtc tatgtgatca accattttat caaacaattg
     4261 acgccctaat actctacctt tgagtcgttg ttcacaatgc gcgactgcac tcttcatgac
     4321 agttgctagc tctatactcg atgccgttgt tgaaaagagc tcatcgcagt aattatctga
     4381 tttcttgata aataatttat tctttgtcct gacctttcgc tttgcagctg tctcccagta
     4441 ttcacaacga attttgtttt caccatatcg ataaaatagc aagaacccga taatttcatt
     4501 atatcgccac tctccgccat atttatcttt taagtagtta ctgctaagga ggccgcctgg
     4561 atttttttca gatatatagg cgcgcatctc ttgattgtat ttttcctcag ttagtcgata
     4621 aactggcatt tcgaataatt tttttaggat aatcatactt catttactct gcgagtgaat
     4681 tgtggttatg gatcagagag gctaagagta aatgaactat ttaaatattc ctgtgataca
     4741 tatcagtaat tttatataaa tccaccattc catcctttac catggggcat ctcctacttg
     4801 ctctggaata ctcatgtcca cctccctgaa acttgcgcta gagttggcga caaaggtcac
     4861 cggccgtgag gagttgggcc ggcagggcga atgcatgaac ggtttttgag ccatggcgaa
     4921 taatggttcg ttcgtaaatc gagcatggct gtatccgcct gcggcaacaa aacagctcaa
     4981 atcgctcaac atacaatcgt gccaagcaac tgtattaggc gcacggcctt tggtcgctga
     5041 tcggcccatg atgccgacgt aaacggcaat ttggtgatcg cgtcgagggt ttcgccaaaa
     5101 gacacgctca ggtccaatgc tatttgggca acaatggcgg cactgatggt gatacccatc
     5161 ttgaggtttt aagcctatgg ccaaggcggt gacctggtat ctcaaggtgg cagagcgagg
     5221 ggattcaggg atgaaaaaaa tgatgttgtc gccattgttg gcggtgttgc tagtaaccag
     5281 ttttttgcca gagaccgcca aggctgaggt gactcttggt gatgtctcac gggccgagca
     5341 gggtgatgcc caggcgcaat ttaagctggg tttgatgcat tacaacggcg aaggttggcc
     5401 acaggacttt aagcaggcgt ttttttggtt tagcaaggcg gccgagcagg gaaatgctga
     5461 ggcgcaatac aacctcggga taatgtacga caacggcgag ggagtgcccg aggataatgt
     5521 gcaggcggtg gcctggtacc gccaagcagc cgagcagggg caaattgccg cgcaattcaa
     5581 gctggggatg atgtactaca ccggtcaggg cgtggcgcag aattatgcgc aagcagtggc
     5641 ttggttccac aaggcggctg agcagggaca tgccgtggcg caaaccgtcc taggggcaat
     5701 gtacgaatac ggcgagggcg tggtaaagga cgataagcag gcggtggcct ggtaccgcca
     5761 agccgccgag cagggacagc caggcgcaca atccaacctc ggggtgatgt acgccaaggg
     5821 ctggggggtg gtgcaggacg ttaagcaggc ggtcgcctgg atgcgcaaag ccgccgaaca
     5881 gggggaatcc gacgcgcaat ttaacctcgg actgatgtat gtcaagggtc aaggagtgcc
     5941 acaggactac cagttggcct atgtctggta ttccgtggca gcggcgaatg gatataaaaa
     6001 tgcggttgag cggagggatg cagcagctaa aaacctcact caggccgatt tgtcgacagc
     6061 ccagcagttg gcgaccagct atttcgatca gtaccgtccc aagccctgac tcgcgacctg
     6121 gcctactgcg catagggggc gttacggtaa accggctttc cttttgctgc gccttccctt
     6181 atatgactag agactaggct ttcaatctgt cttagggaag gcgcgaataa gtcaccaaac
     6241 tccaaaacat gcatctgtag tccaattgaa tttaattggc taaagtcttt atttttgttg
     6301 tggtgtgcgc ttgtttctat cgcctttagt tatagttggg gagcccgcag aattcggaaa
     6361 aaatcgtacg ctaaggtttt ccgggcatcc gtaagggccg aaacttcccg tcttccagtc
     6421 tgcggctctg ccgccagacg taatcgccgg ttaggttgat gtgctcccag cccagcggcg
     6481 acaggaattg cagcagctcg ccgtccaccg gcttgccggc ctcgaccaac ccctgggtgg
     6541 cgcgctccag gtacaccgtg ttccacagca cgatagccgc cgtcaccagg ttgaggccgc
     6601 tggcccggta gcgctgctgc tcgaagctcc gatccctgat ttccccaagg cggttgaaga
     6661 acaccgccct ggccagcgag ttgcgcgcct cacctttgtt caggccggca tgcacgcggc
     6721 ggcgcagctc aacactttgc agccagtcta ggatgaacag cgtgcgttcg atccggccca
     6781 gttcgcgcag ggcgacagcc aggccgttct gacgcggata gctgccgagc ttgcgcagca
     6841 tcagcgaggc ggtaacggtg ccctgcttga tcgagctggc caggcgcagg atgtcgtccc
     6901 aatgagcgcg cacgtgcttg atgttcaggg tgccaccgat cagcgggcgc agcgtcgggt
     6961 aggcctgcac gccctgcggc acgtacagtt tggtttcgcc gaggtcgcgg atgcgtggcg
     7021 cgaagcggaa gcccagcagg tgcatcaggg cgaagacgtg atcggtgaaa ccggccgtgt
     7081 cggtgtagtg ctcctcgatc cgcaggtcgg actcgtgata cagcaggccg tcgagcacat
     7141 aggtggaatc tcggacgccg acattcacca cgcgtgtgct gaacggcgcg tattggtcgg
     7201 agatgtgggt gtagaacagc cgtcctggct cgctgccgta cttcgggttg acgtgcccgg
     7261 tgctttcgcc ccggccgccc gcgcggaagc gctggccatc ggaggacgag gtggtgccat
     7321 cgccccagtg ggcggcaaag gcatggcggt actggtggtt gaccaactca gccagggccg
     7381 ccgagtaggt ttcgtcgcgg atgtgccacg cttgcagcca ggacagcttg gcgtaggtca
     7441 gtccggggct cgactcggcc atcttggtca gcccgaggtt gattgcatca ccgagaatcg
     7501 cggacagcag caacgtccgg tctttggcct cggccccgtc cttcaggtgg gtgaagtggc
     7561 ggctgaagcc cgtccagtcg tccacgtcca tcagcagttc ggtgatcttg atgcgcggca
     7621 gtaactgact ggtctggtcg atcagcgcct gcgcccgatc cggcaccgcc gcatctagcg
     7681 gggtgatctt caacccggac tcggtgagga tggcatcggg cagctcgttg tccttggcca
     7741 ggcgggcgac agtggccaac tgctcgtcca gcagctgcaa gcgctcttcc agatactggt
     7801 cgctgttcgg gttgatcgcc agcggcaggg cctgttcccg cttgagcgcg gcgaacttct
     7861 cggccagcag caggtagtcg tcgaagtcgc ggaactgccg cgagcccttg acccagatgt
     7921 cgccggagcg cagggcgttc ttcagctcgg acagggcgca gatttcgtag aagcgccggt
     7981 cgaggccttc cggggtgatc accagtggct tccagcgcgg cttgatgaag gcggtgggag
     8041 catcggccgg caccttgcgc aggttgtcgg cgttcatctc gcgcagcgtc tgcacggctg
     8101 ccagcacgcc ctgcgcggcc ggggcggcgc gcagctccaa tacctccagc agagccggcg
     8161 tgtagcggcg cagggtggcg aagttctcgc cgactaggtg caggtggtcg aagccctccg
     8221 gccgggccag cagctcggct tcgctgacgc tctcggtgaa ctcgtcccag ggaatcaccg
     8281 cctcgatggc ggcatagggg tcgctgccgg cttccttggc ctccagcagc gcctggccga
     8341 tcttggagta caggcgcacc ttgtcgttga tcgccttgcc ctgcttctgg aactgctgct
     8401 gatgcttgtg cttcgcgccg ctgaacagct tgactaggat gcggtcgtgc agatccacca
     8461 gctcatcaat cacggttgca gtgctctcca gcaccacggc ggccagggtc gcatagcgcc
     8521 gctgcggctc gaacttgccg aggtctttgg gcgtcatctg cccaccctcg cgggccagct
     8581 tgagcaggcg gttctggtgg atgtgccggc ccaggacttc gggcaagtcc accagctgaa
     8641 atgtcttcag ccgctcgatg tgctcaagca tgtgccgaga gttgggtttc agcggtgcct
     8701 ggcgcagcca ggtcaaccag gtgatgctgc tgccggcctt gagcttcaac agctcgtcta
     8761 gcttggcccg atgcgagtcc gtgagcggtt caaccaaggc gcggtagacc cgccgattgg
     8821 cccgcgcaat ggcttccgag caggcccggt caatcacgct cagcgccggc aggatgcgcc
     8881 gcttctgccg caggctctcc agcgcctgac cggccagcaa caagctcttg tcggtctgct
     8941 gggccagttc ggtcaactca cgcaccaagg cgcggaagtc ggacaggccg aacggggcca
     9001 gttgcaggta ggtgcgcagc tccagggcgt gctcgcgacg ggtcacgtcg cgctcgccgt
     9061 actttgccca gctcgtcgga tcggcctgga tttgcttggc cacccacagg atgaccggct
     9121 cgggcagctc gctgtcagtg cccagcgcgt agccggggta gcgcagcagg cagagctgca
     9181 cggcgaagcc gaggcggttg gcgtcgccgc gccgctgacg gatcagcgac aggtcggagt
     9241 cgttgaaggt gtagtagcgg atcaggtcat cctggctttc tggcaacgcg agcagggtgc
     9301 cccgctccgt ggccgagagg atcaagcgac gcggcatgtg tcagtcgtcc gtgcggaggt
     9361 actggtagag ggtttcccgg ctgatgttga actcgcgggc aagctgcgcc ttgggctcgc
     9421 cggccgtcgc tcgctgccgc agggtagcag cctgctcatc ggacagggct ttcttgcggc
     9481 cccggtacgc gccacgctgc ttggccaagg tgatgccctc acgctgccgc tcgcggatca
     9541 gggcgcgctc gaactcagcg aaggccccca tcaccgacag catcaggttg gccatcggcg
     9601 agtcctcgcc agtgaacacc aggccctcct tcaggaactc gatgcgcacg ccgcgttgag
     9661 tcagcttctg taccaagcga cgcaggtcat cgaggttgcg ggccagccgg tccatgctgt
     9721 gcaccaccac tgtatcgcct tcgcggacga agctcagcag cgcttcgagc tgggggcgct
     9781 gggtgtcctt gcccgatgcc ttgtcggtga acaccttgct cacctttgtc tgttccagct
     9841 ggcgttccgg gttctggtcg aagctgctga cccggacgta gccgatgcgg tgcccctgca
     9901 cgatgtctcc ttggttgaag gcggcttaag tgctccttct gttccgttgt gcctcaaacc
     9961 ccgtttctgt caggctgaaa tctatgacct tcgcaggcat gtgtcaaaaa atgcgaaaga
    10021 tgactctatt ctgacgaagc ggcgcggccc tgcctgacat ccagttaggg tatagcctag
    10081 attgacatgc gcgatgcaac ccttaacttg cttgcaccta tcgtttccat gctagcttta
    10141 tcgtaacgct aaggaagctc tgaaaaagcc catgtttcgc gaaatcaccg ctctgtaacc
    10201 cgcatggttg ctgggatgca tttctcgagc gggggctttt tcagaccttc cttagcttag
    10261 cgtacgattt tttccgaatt ctgcggttcc ccctggaaga cctacgcaag ttgggccagc
    10321 tcagaggtgg aatcaacgaa ggcgagcgaa tgaggcatct tttctggcgt cttaactttc
    10381 tccttctctc cggggcaaca aacagcgccc agatgtacca tgaggccgcc gctctttcct
    10441 ccgagctgga tactcgttgg tcttaccgct ccaaagagct tatgacgctc tacagcaagg
    10501 cgaaatccta tgaggctggg gaacgtgtcg agttcggcgg aaagtcgttt gcaccgctat
    10561 acacgcccaa aaacgacacg ctgatcaacc tattccagat ctcacagcaa gaacaagagc
    10621 aactgaagac gattatcagc actgacgagg ctcagaagcg ccgcagagag cgcgatagac
    10681 tgcgtgatga agaacgtcgc cgcgccgctg gccagcttga gcgtgaagcc tatgaagcca
    10741 actcattgag caggcaaaag ccctgggaag ctatgggcat gagccgggct aaatggtatc
    10801 gcctgggcaa gccttcacct caacaaaaca gtgagacaag tccctcccct attactaatg
    10861 gcgaagcctc agcggttgcc cttcaggcgg ccaggtgtaa agccgtttag atggctattt
    10921 caaagtgagt gagatttcgt aacggatggc agccctagag gctgctttct tttgaggggt
    10981 tagcaggcgt atagccatgc tggatctcag tctatcacta cctgcttaat attccacctt
    11041 tagatccggc agcagttcga ccaggtggcc aacttaccag gcaccggcag cagctcgacc
    11101 gggtggccaa gttcagatct ggacgccaga aggaaatcaa ccaggtggcc aacttaccag
    11161 gcaccggcag cagctcgacc aggtggccaa gttcagatct ggacgccaga aggaaatcaa
    11221 ccaggtggcc aactcaccag gcatcggcag cagctcgacc aggtggccca tttcgtacgt
    11281 acgaaatcag gcgacgctat gcgaaatctt ggcggcaatc ccccgcgact acgtgatttt
    11341 tttaacgtag agcgcgcttt ttcttgccat agtaggccat tttggcctat aatcttaatt
    11401 aagaagaccg ggcacccgcc acggtcaata ccggagaact ccgatgatcc acacagctaa
    11461 ccgcaccttt caccaactct atcgagaatg gatacgcgaa cgccgcgagc atatgcacaa
    11521 cgttttgacc tgggagcgtg atcgttacgg tgctcgcctc gtcggtctgt tttatcgtta
    11581 ctgcaaggtg gccaacccct ttccccgttg cactctgaat actcggatca actaccgcgc
    11641 ccatgcggtg aatctgccag attggccagc ccgcagcctg gagctgaata aaatgtggct
    11701 cagttggaga gaaaaaaagt aggccgattt ggcctatttt ttattgtacc cgcttgacac
    11761 aataggccaa aatggcctat tatatatctc agaaggccgg gcacccgcca cggtcaatac
    11821 cggagaactc cgatgatgca aacagaactt aatcccctga tctgctccct ggtcgccacc
    11881 cctcgccgta tggctgcaat gccccgctat gtaggccgtt tctatgtggt tttcgagtcg
    11941 atgctttacc agcaaatgaa agggctctgc cgcgagtatc gcggggctta ttggcttatg
    12001 tgggagctgt cgaacggcgg cttttatatg gctcctgggc gtcgtgatga aatgctgaac
    12061 atcgaggcca tgaactactt tagtggccaa atgagcgccg atgctgccgg gattaccgct
    12121 tgcctctacc tctatagcca tctgtcattt cacacagaag gcgctgacca ggagcggttt
    12181 tcaaggctgt atcacagctt gcgggattgg gcttgtgagc atgacgaaaa agaggccatc
    12241 ttggccgcaa tagactagca acagaaagcc ccggtgatgg ccggggctct taaaggaggt
    12301 gcataggtag aaaaagaaat ggtgcccctg gtatggctgc aaccaatcac aggggctttc
    12361 accggtcaat ttgaggataa acgcgatgaa tacggatatt gtatcacttg caaaacacat
    12421 tggcgacgct ctgacggccc gccgccccgt tcatatgccg cgcatgaaga tgcgggagct
    12481 tggcttgctc ttgattgaac tgaaggcgta tcgggaggcc gccgcgaccg ttacccattg
    12541 ataaaaaagc cccggcattg accggggcta tttgaggatt tatcgcatga ttagacctga
    12601 aacgcttagg ccgttcgctg aagattggca ggctccaacc gccgatgaaa tcaaagaggt
    12661 gttggagctg attaggcaac gaaaagggct tagtaagcct ctcagtggcg ttgatgtcgc
    12721 tgatctcgtt ggtttgcctg gtgagagagg cagcggaaag ggaacccgaa ccttcaggcg
    12781 ttgggtgagc aaaaccaacc ctagccctat tgcttatggt gcctggtcta tcttggccca
    12841 cctggcaggt ttcggggcta tatgggacgc tgaccgggat tgaaaccatg accgaacata
    12901 aggccgaacg tgctccctgg ggagacttcc cggcagtagt gaggaacggc gatctaaagg
    12961 atctctctaa agaacctgaa tacgaagccg ccaaacatgg cgaccacaag gcgatgagct
    13021 ataagcgcat gaagccggcc gaggacgaat tgcattgcga gatcaaggcg ctgcttgatc
    13081 gcgccaaggc taccgacgac caggagcgta acgagccgga gctggacatt cctgccgaga
    13141 tttctcgccg cgagaagcgc ctggaggcga tccaggcggc aaaggcgcgc ctggaagcgc
    13201 gccagcgtga agcggaccag gcccgggggc gcagcgaaga cgatggccgc cggcctcgcc
    13261 atccggatgg ctcggacaag ggcggtggct cgtacaaacg cgagtttggt gtgccggatg
    13321 accgtgatca ggaaagcttc accgatccgg acagccggat catgaaacac gccggtggtg
    13381 gctccgagca gagctacaac gggtacacag cggtcgatgc cgagcaccag atcatcgtgg
    13441 cggcggagtt gaccaactgc gccgcggaca gtcaggcgct gctgggcatg ctggcagcag
    13501 ttcaggccaa caccggagaa atgccggccc agacgctggc ggatgcggga ttccgtagtg
    13561 aggctgttct ggcaaaggtc gccgatcacc acggcgatgt catcgttgcc ctcggccgcg
    13621 agggacgtga agatgccaag gtcaatgcca agacccatcc gcatacggcg gcgattgcgg
    13681 cgaaattgaa aacggagcaa ggcgatgcag cttaccgccg gcgcaagtcg atcgtggagg
    13741 ctccgaatgg ttggatcaag gcggtgatgg gattgcgtca gttcagcatg aggggcctgg
    13801 acaaggtgca agccgagtgg aagctcgtct gcatggcgct aaatctgagg cgaatggcgt
    13861 atctgtgagg gcgaaggtta aatggggcgg ctcaaatgca ccccagtcgt cataacacgc
    13921 cgcgcgccgc aagattggta tccttggcgc cgacgccttg ccaattgcag agagcgccgc
    13981 cgccatcgtc agtgctctac agaaaaccgg tcacacggct ctgccgcgca gactcctagc
    14041 ctaaatgtga cagtggttgg taatccatgc cgcccgcaag ggcggcggtg gtgggccaat
    14101 agatgatttt cagagcctta ctgcccgttg acgcccaatc cctcgagcgc gagtctagcc
    14161 gcagcggcga tgacggcctc gctgtgcttg tcatccttgt taggcgcccg ggtgtagacg
    14221 gccaacacaa taggtgcgcg cccagtgggc cagacgacgg catagtcatt tgccgtgcca
    14281 tacactccgc aggttccggt tttgtctccg actgcccagt ctgccggcac cgccgcgcgg
    14341 atgcggtggt tgccggtcgt gtttcccttt agccaatcaa caaactgctg ccgctgcggc
    14401 gcagccagtg cagagcccag tgtcagtttt tgtaagcttt ccgtcacggc gcgcggcgat
    14461 gaggtatcgc gcgcatcgcc tgggatggcg gagttcagct ccagctccca gcggtccaga
    14521 cggaacgtgg tatcgccgat agagcgcatg aaggccgtca gcccggccgg gccgcccaac
    14581 tccttcagca acaaattggc ggcggcgtta tcactgtatt gcacggcggc cgcggacagc
    14641 tccgccaccg tcatgcctgt tgtcagatat ttttccgaga tgggtgacca cggaaccagc
    14701 gcatttttgc cgtaacggat gggtgtgtcc agcaagccgg cctgctgctg gctgcgagcc
    14761 agcacagcgg cagcaagaaa gcccttgaat gagctgcaca gtgggaagcg ctcctcagcg
    14821 cggtaactta cagttgcgcc tgagccggta tccatcgcgt acacaccgat ggagccgcca
    14881 aagtcctgtt cgagtttagc gaatggttcc gcgacgaggt tggtcagcgc ggtggcagaa
    14941 aagccagcca gcggccatga gagacaagac agcagaacta gacggcgata cagtgacatc
    15001 aacgatattc cttgtttgaa ggtggagcta ggtgtagcgg ccggatgtaa tcaggccgct
    15061 acagctggga ttaggggtct gacgctcagt ggaacgaaaa ctcacgttaa gggattttgg
    15121 tcatgagatt atcaaaaagg atcttcacct agatcctttt aaattaaaaa tgaagtttta
    15181 aatcaatcta aagtatatat gagtaaactt ggtctgacag ttaccaatgc ttaatcagtg
    15241 aggcacctat ctcagcgatc tgtctatttc gttcatccat agttgcctga ctccccgtcg
    15301 tgtagataac tacgatacgg gagggcttac catctggccc cagtgctgca atgataccgc
    15361 gagacccacg ctcaccggct ccagatttat cagcaataaa ccagccagcc ggaagggccg
    15421 agcgcagaag tggtcctgta actttatccg cctccatcca gtctattaat tgttgccggg
    15481 aagctagagt aagtagttcg ccagttaata gtttgcgcaa cgttgttgcc attgctgcag
    15541 gcatcgtggt gtcacgctcg tcgtttggta tggcttcatt cagctccggt tcccaacgat
    15601 caaggcgagt tacatgatcc cccatgttgt gcaaaaaagc ggttagctcc ttcggtcctc
    15661 cgatcgttgt cagaagtaag ttggccgcag tgttatcact catggttatg gcagcactgc
    15721 ataattctct tactgtcatg ccatccgtaa gatgcttttc tgtgactggt gagtactcaa
    15781 ccaagtcatt tttcaatatt attgaagcat ttatcagggt tattgtctca tgagcggata
    15841 catatttgaa tgtatttaga aaaataaaca aataggggtt ccgcgcacat ttccccgaaa
    15901 agtgccacct gacgtctaag aaaccattat tatcatgaca ttaacctata tgtcaagacc
    15961 cggctggtta tacacgcgtt tcctgaacaa ttcagggcgt ttttcatgcc attccttgag
    16021 cgcctgaacg ggtgttttgt gttggagcgc gcgttgcgga atgctgtggt tgtagatctt
    16081 gacgtaattg cgcagcgtcg attccagttc ggcagctgaa ccaaaacggg tctggttgac
    16141 gatgtcgctg atacgaccgt tgaagcgctc caccatgccg ttggtctgcg gatgacgagg
    16201 cgggatgagc cggtgctcga tgccgagctg cttgcacagg cggtcgaaca cgtgtgtgcc
    16261 gctgggttcc ttcttcttgc cgccagccgt gaagcggtcg gtgaactggc tgccgttgtc
    16321 ggtcagaagc ttgacgatct tgacgggaca ggcttgctgg actttgttga ggaagtcgcc
    16381 actgctgcca tcggtctggt cggcatagag ctcgatgaag acccagcgcg tagcacggtc
    16441 gatggcaacg aagagatagc gccttgccgt ctcgtcgggc atctgcggca ggtacttgat
    16501 gtcgatgtgc acaaagcccg gctcgtagtc cttgaaggtc tttttcgtgg cgggcgcagt
    16561 gccttcctgc tcgaccaggt tacgtagatc cgagacaccg tggcggcgca ggcaacgtcc
    16621 caggccggca cgcgagacgg ctggattgat gaactcgcgc gtgaccgcca gcaggtcgtc
    16681 cgtgggcagc agcaacgtct tgcgcagctc caccacgatg agctcctgct cgggcgtgag
    16741 cgtcgtgtac atcttgttcg gcgcatgcga cttgtcttca ggagactcgc ggttttgcca
    16801 ctttcggatg gtttggcggg tgacgttgta catcctggcc agttcggcct gcgggagcgt
    16861 cgagttcctg atttcctcac ggatcaggtg ggtagtacgg gcttggctgt gcagtgcctg
    16921 ggtcatcgag ttgccagtga agagtcggat tggaacagtg tacgcaaaac gtgtctggcc
    16981 ttgaagagcg gccagctacg catgggtaca tgatcccacg agtccagaca cctataaaaa
    17041 taggcgtatc acgaggccct ttcgtcttca agaattttat aaaccgtgga gcgggcaata
    17101 ctgagctgat gagcaatttc cgttgcacca gtgcccttct gatgaagcgt cagcacgacg
    17161 ttcctgtcca cggtacgcct gcggccaaat ttgattcctt tcagctttgc ttcctgtcgg
    17221 ccctcattcg tgcgctctag gatcctccgg cgttcagctt gtgccacagc cgacaggatg
    17281 gtgaccacca tttgccccat atcaccgtcg gtactgatcc cgtcgtcaat aaaccgaacc
    17341 gcgacaccct gagcatcaaa ctcttttatc agttggatca tgtcggcggt gtcgcggcca
    17401 agacggtcga gcttcttcac cagaatgaca tcaccttcct ccaccttcat cctcagcaaa
    17461 tccagccctt cccgatctgt tgaactgccg gatgccttgt cggtaaagat gcggttagct
    17521 tttacccctg catctttgag cgctctgatc tgaatatcga gggactgctg gctggttgag
    17581 acccgcgcat aaccaaaaat tcgcataaaa tgtaccttaa atcgaatatc agacacgatg
    17641 tgtctattat gccaaaatga cgatttaatg gacactcaaa cgaagccgtt ttactatgtc
    17701 tgataattta taacatttcg tacggttgca aaaatgttac taaatgcccg tcaggcaggg
    17761 aggccgatat gcccgttgac tttctgacca ctgagcagac tgaaagctat ggcagattca
    17821 ccggtgaacc ggatgagctt cagctggcac gatattttca ccttgatgaa gcagacaagg
    17881 aatttatcgg aaaaagcaga ggtgatcaca accgtctggg cattgccctg caaattggat
    17941 gtgtccgttt tctgggcacc ttcctcaccg atatgaatca tattccttcc ggcgtccggc
    18001 attttaccgc cagacagctc gggattcgtg atatcaccgt tcttgcagaa tacggtcaga
    18061 gggaaaatac ccgccgtgag catgcagcgc tgatacgtca gcactatcag tatcgtgaat
    18121 ttgcctggcc ctggacattt cgccttaccc gtcttttata tacccggagc tggataagca
    18181 acgaacgtcc tggcctgctt ttcgatctgg cgacagggtg gcttatgcaa catcgtatta
    18241 ttctccccgg agccactacg ctgacccggt tgatttcaga ggtaagggaa aaggcgacgt
    18301 tgcgcctgtg gaacaaactg gcactgatac cgtcagccga acagcgttca cagctggaga
    18361 tgctgctggg gccaactgat tgcagccgcc tgtctttact ggaatcactg aaaaagggcc
    18421 ctgtgaccat cagtggtccg gcgtttaatg aagcaattga acgctggaaa actctgaacg
    18481 attttggcct gcatgctgaa aacctgagta cactcccggc tgtgcgcctg aaaaatctcg
    18541 cacgttatgc tggtatgact tcggtgttca atattgccag gatgtcaccg cagaaaagga
    18601 tggcggttct ggttgccttt gtccttgcat gggaaacgct ggcgctggat gatgcattgg
    18661 acgttctgga cgccatgctg gccgttatca tccgtgacgc cagaaagatt gggcagaaaa
    18721 aacggctccg ctcgctgaag gatctggata aatctgcatt ggcgctcgcc agcgcatgtt
    18781 cgtacctgct gaaagaagaa acaccggacg aatcgattcg tgctgaggtg ttcagctaca
    18841 tcccaaggca aaagctggct gaaatcatca cgcttgtccg tgaaattgcc cggccctcag
    18901 acgataattt tcatgaagaa atggtggagc agtacgggcg cgttcgtcgt ttcctgcccc
    18961 atctgctgaa taccgttaaa ttttcatccg cacctgccgg ggttaccact ctgaatgcct
    19021 gtgactacct cagccgggag ttcagctcac ggcggcagtt ttttgacgac gcaccaacgg
    19081 aaattatcag tcggtcatgg aaacggctgg tgattaacaa ggaaaaacat atcacccgca
    19141 ggggatacac gctctgcttt ctcagtaaac tgcaggatag tctgaggcgg agggatgtct
    19201 acgttaccgg cagtaaccgg tggggagatc ctcgtgcaag attactacag ggtgctgact
    19261 ggcaggcaaa ccggattaag gtttatcgtt ctttggggca cccgacagac ccgcaggaag
    19321 caataaaatc tctgggtcat cagcttgata gtcgttacag acaggttgct gcacgtcttt
    19381 gcgaaaatga ggctgtcgaa ctcgatgttt ctggcccgaa gccccggttg acaatttctc
    19441 ccctcgccag tcttgatgag ccggacagtc tgaaacgact gagcaaaatg atcagtgatc
    19501 tactccctcc ggtggattta acggagttgc tgctcgaaat taacgcccat accggatttg
    19561 ctgatgagtt tttccatgct agtgaagcca gtgccagagt tgatgatctg cccgtcagca
    19621 tcagcgccgt gctgatggct gaagcctgca atatcggtct ggaaccactg atcagatcaa
    19681 atgttcctgc actgacccga caccggctga actggacaaa agcgaactat ctgcgggctg
    19741 aaactatcac cagcgctaat gccagactgg ttgattttca ggcaacgctg ccactggcac
    19801 agatatgggg tggaggagaa gtggcatctg cagatggaat gcgctttgtt acgccagtca
    19861 gaacaatcaa tgccggaccg aaccgcaaat actttggtaa taacagaggg atcacctggt
    19921 acaactttgt gtccgatcag tattccggct ttcatggcat cgttataccg gggacgctga
    19981 gggactctat ctttgtgctg gaaggtcttc tggaacagga gaccgggctg aatccaaccg
    20041 aaattatgac cgatacagca ggtgccagcg aacttgtctt tggccttttc tggctgctgg
    20101 gataccagtt ttctccacgc ctggctgatg ccggtgcttc ggttttctgg cgaatggacc
    20161 atgatgccga ctatggcgtg ctgaatgata ttgccagagg gcaatcagat ccccgaaaaa
    20221 tagtccttca gtgggacgaa atgatccgga ccgctggctc cctgaagctg ggcaaagtac
    20281 aggtttcagt gctggtccgt tcattgctga aaagtgaacg tccttccgga ctgactcagg
    20341 caatcattga agtggggcgc atcaacaaaa cgctgtatct gcttaattat attgatgatg
    20401 aagattaccg ccggcgcatt ctgacccagc ttaatcgggg agaaagtcgc catgccgttg
    20461 ccagagccat ctgtcacggt caaaaaggtg agataagaaa acgatatacc gacggtcagg
    20521 aagatcaact gggcacactg gggctggtca ctaacgccgt cgtgttatgg aacactattt
    20581 atatgcaggc agccctggat catctccggg cgcagggtga aacactgaat gatgaagata
    20641 tcgcacgcct ctccccgctt tgccacggac atatcaatat gctcggccat tattccttca
    20701 cgctggcaga actggtgacc aaaggacatc tgagaccatt aaaagaggcg tcagaggcag
    20761 aaaacgttgc ttaacgtgag ttttcgttcc actgagcgtc agacccctta tccgtttcag
    20821 cagtcatgat attcccctca ttaaatcagc ccgaggcgct cgagctctgc acggaggtca
    20881 ggggcaaggc cgtcaggctt aaaagtcctc caccccccgc cagaaatttc gtgaacttgc
    20941 cgctgagtcc ctgtttgagt tatccagatt tgtccatgtt ccttagcggc attaattgct
    21001 gcatcacggg ttcggtggct ttttatatca cggtctttgc ctgctcgcag gctgtaaaac
    21061 ggagcgttct ttgtggccat tcagatacca ccttcttcaa ctaccgggcg ctttgtcgga
    21121 tctagccaag ccagagcttc attcttgcat tcttcgcgag acgcgctgta cccggcctgc
    21181 accatgaccc gtccatactc agctgccagg tattcataag catcggccat gtcagtcagg
    21241 gtctgggctg cgtcgacatt tccggaatgg tacagaccct ttgcttgcat tcgtactttg
    21301 ggaattcctt tgatgctcat gatgttctct ctttggtcgg atagataata tttcgattag
    21361 ttgaatgtac catattgctg aatgacgcaa ctcctggtgc gctcccggct tggttaatct
    21421 aggaatgaca ggtcgcaatc acgaatgagg atctgctgtc gtgatcatgt cggggggggg
    21481 gagtaaggat agttgggggg gggccactaa tgggtggcca tcctaaagtc tcggtggcgc
    21541 gagcccctac gatgggggct ttgcgctgcg ctgggacacg ccagagcacg cagctccgat
    21601 gtcaacaatt aatagcgagc ggcgaattcc tggccctttc tatgtcggta aatttcccgg
    21661 gcccgcttat tgatttctcc gttgtgtgac aagctcgcca agatcccaac cgcagctatt
    21721 agccacggaa ttgaccagag agaaaagtat ccaacgaaat cttcatgttg ccaaacatca
    21781 tccaagccac aggcaagacg aactatggcc gcagccatac agatagagat ggtaatgact
    21841 gtcaatcagc atcgaaaaat gaccagggtt cagcgtccaa aattgaccag ggttagctgg
    21901 ctgatttcat cctctgtttg aagcggtagg agtcgtttcc tgtctcgatg atctcgcagt
    21961 gatgggtgat cctatccaac atcgccgttg tcatcttctc atccgtaaat accttgctcc
    22021 attcgctgaa ggccaggttg gtggtcagga tcaggctggt gcgctcgtac agcttgctga
    22081 tcaggtgaaa tagcagggcg ccaccgcttt cggcaaacgg caagtagccc agttcgtcca
    22141 ggataaccgc atcgacattg accagccggt tggcaagctg cccggctttg cctgccgcct
    22201 tctcctgctc cagttggttg accagatcca ccacgccgta gaaacgcact cgcttgcccc
    22261 ggcgcacggc attgcgcccc agggcgatgg ccagatgggt tttacccgtc ccggttccgc
    22321 ctatcagcag cagattgcgc ttctgctcca ggaagtcatc tctatccagc gcggacaggt
    22381 gcacggggct gaccggggtg tctgcggtct cgaagctgtc caggtccctg gccagcggga
    22441 acttggcgat gcccatctga tagcggatcg agcggcactg acgttcggat tcttcggctt
    22501 cgatcatccg tttgagccac tgctccggcg gtggtaaggg acgctcccga tgcgccagca
    22561 gctcgtcgca cagcgccgcc ataccaaaca gtttcaaccc ctgcaggcgc tggtaaattt
    22621 catcggctga catgctgacc tcccggtaac aggctgtcat agcgttggca gttggcctgc
    22681 ggcggctgtg caagcggcac cacctgagca tggagctgtg gcacctcgac ggggcggcgc
    22741 agccgctgca ggtggttgag taccagctcg gccgagctgc cgcccagcag cagtacctgc
    22801 tggcaggctt gctccaacag gtcgagtccg tcctgccggg cagccaacag tagcttgacc
    22861 atgtcccggt caccgccctt gcggctcagc agttgctgct gtaagcggct caaagccggc
    22921 ggtaacaccc actccttgaa gggagcaccg tggcgcagcg cgccgggttt gtgctcgagc
    22981 aggccgaggt aatgccaggg gtcgaactgg gtcttgtccc ggccaaactg gcggggatgc
    23041 tcggcaataa gctcgctctg ggcatacacc tggagccggt cagcgaagac ccgggctgtg
    23101 acatgacgat gggcgtaacg gctgtcgaca ctgtaggtgt tgcggtcgaa gtggatgagg
    23161 caggtgctgt caacccgcag ctcccgctcc acatagccat tgaagcgcgc agccaggggg
    23221 cgcagggtgg tccgttcctg ctcgaagcgc tgccacactg tttgcgaggg gtcgtccggg
    23281 tgggggcgtg tttgtgctgc ctgctccagc tcctggataa gccgacggtt gagctcggcc
    23341 aggctgtcga ccttgcgccg gggtgtaaag cagcgccggc gcacatcctg aacctgtttc
    23401 tcaacctggc ccttttccca acccgaggca ggggtgcagg ctaccggctc aatgacgtaa
    23461 tggctcatca gcgccaggaa gcggggattg aagcggcgct ctttcccctc aagtacttgg
    23521 tcgatacagg tcttgaggtt gtcgtagatg ccctggcgtg gcacgccgcc ccagtagtga
    23581 aaggccgcat cgtgagcggc aaacaccatc tcctgggttt cgcgaggaaa caccatgacg
    23641 aagggctggc ggctgtgggt gaggcgaaaa tgggcagcct tgacccgctg caccacgccg
    23701 ccgatctcca cctcttcctc gctccagtca aactgatagg cctcaccagc cgcgaacgtc
    23761 agggggacaa aggcagccac tttggctgac tgctgtttat agtcacggac gaagcgctgg
    23821 acgctgtcgt aggccccctg gtagcccagg cgttgtaggt cttcgaagag ttgcctggca
    23881 cagcggcgtt gtcgcttggg ccgcttggca tcgaggtcca gccactgggt cagtgtcgac
    23941 tcgaattcac cgagcttggg cctggctggc tgtggacggc ggtacttggg cggttcggag
    24001 ggaggttggc gaaggtattt gcgaacggta ttgcgagaga gtcctgtgac tttagcgatg
    24061 gcgctgatgg actggccgtc cacctgatgc atacgccgga tcttcaacac ggtttccatg
    24121 attaacactc caggttctcc gatccaaaga tcggatagtt gcacacactc cggggtggtc
    24181 aaaattggac gctgaaaacc ccggaaacct ggtcattttt gcgcgctgat caacaggcgc
    24241 cccttttggc ttcctatcaa aatcgcaatt acagattccc gtatttctgc aaaagcagtt
    24301 cgcgcacctc gtccgcgatc ttggctccgc gcgatgcaca ttgcatcttg attgcgcggt
    24361 gcaggctttc ggggatgtcg atggtgagcc gcttcatcgg ctcaggtgca ttgccggtgc
    24421 tgcggttctc tacccactca tcggcggagg cctgcgcact cttgctggtc ggcttggcgc
    24481 cgattgtgac cttcttgctc atcgtgcaat ctccatcaat tctgccatga cggcatcgat
    24541 ctctgcggct gctgggccgg tctcatcagt ttcatgaaca gcgcggcctt gggctgcggc
    24601 ctctgcgaac actacgcgct gggtgatact ggcggttagg acaggtatgg ggtaggcggc
    24661 cagggctgca ccaacatccc gccctatggc cgtatttgcg attttacgat taaccacaaa
    24721 agcggctttc agtccttcct tgtagatgcg agcctcttca atcagcttca ccacctcgtc
    24781 tgctgcccag atgtcgtagg gactgggttg taccgggatc agcaccacat cagcggccat
    24841 gatcgcggag cgagcgaggt cggttacccg tggcggtccg tcgatgacaa tgtggtcata
    24901 gccctggccg agttgtccga tctccttatg cacggtggct ctggggaggc cgacgaccga
    24961 gaacaggggc tcgccatcgc gagctgcggc ccagtccagg gcggagcctt gtggatcggc
    25021 atcgatcaga agaacccgaa agccgcggcg ggccaagcta gccgccaggt tcacgctgag
    25081 ggtggtcttg ccaacgccgc ccttctggtt gagcagtccg atgatcatgg ttgaattctc
    25141 attatttatg gttttgtaaa aatacagaaa accacatgca atgagcaatc aaaataagtt
    25201 ccagacccac tttgcttgct tccccagttc ccccgagttc tggttgtgca acggcatcgc
    25261 cagcactaca atgtaattgc gtttgaaatt acgaaatgag gttactatgg gcacgattaa
    25321 cctgcgcatc gatgacgatc tgaaggctcg ttcatttgcg gtgctggaca aattgggggt
    25381 gaccccctcg gatattctcc ggcaaaccct ggagtatgtg gcctctcaag ggcggagccc
    25441 gtttcgcaca actgtggtga cggaggatga agaggcattg ttggccatcg tgcgcgagcg
    25501 cttggccagc ccccagaagg gcatcaaggt atcgctggat gacctttgaa ctcgagtttg
    25561 atccgcgagc gtggaaagag tggaaaaagt tgggcgatac cgttcgccag caattcaaaa
    25621 agaaactgtc agaggtgatc gagcgcccca ggattgaggc aaacaggctg aatgggatgc
    25681 ctgattgcta caagataaaa ttgcgtggcg ctgggtatcg gctggtttac caggtacagg
    25741 atgatcgagt ggtggtcttc gtagtcgcgg tggggaagcg tgaacgggaa gaggtgtatc
    25801 tggatgctat gtcgcgtctt gattagcgaa gatttgtaag gtgtggccac ctgcggtaac
    25861 gtattgccca gaaaagacaa accccgaatc tcttatcttc atcttggcgg agtcggtaag
    25921 agagttcggg gctaggcact aaacctatgg gaaaagttta acacatggat cagcccaaac
    25981 aaccctccgt tttcccttgt atgaaggatt acggattttg caccgccagt ttgcgcggtg
    26041 ctcgatggta aaatcagtct ctcaagcctc gtttctcgaa agattgcctc accgacccta
    26101 ctgcaccgat gatccggcgc aggggctg
//
