LOCUS       NZ_CP090631            13636 bp    DNA     circular CON 08-DEC-2023
DEFINITION  Klebsiella pneumoniae isolate KpBO_TO1 plasmid unnamed2, complete
            sequence.
ACCESSION   NZ_CP090631
VERSION     NZ_CP090631.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN24648676
            Assembly: GCF_021485025.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 13636)
  AUTHORS   Gaibani,P.
  TITLE     In vivo emergence of Imipenem/relebactam resistance in KPC-producing
            Klebsiella pneumoniae mediated by increased blaKPC copy number and
            porins
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 13636)
  AUTHORS   Gaibani,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JAN-2022) Microbiology, Policlinico
            Sant'Orsola-Malpighi, Via Massarenti 9, Bologna, BO 40138, Italy
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 20x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina iSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/08/2023 10:55:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,573
            CDSs (total)                      :: 5,450
            Genes (coding)                    :: 5,346
            CDSs (with protein)               :: 5,346
            Genes (RNA)                       :: 123
            rRNAs                             :: 9, 7, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 7, 8 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 48 of 104
            Pseudo Genes (incomplete)         :: 57 of 104
            Pseudo Genes (internal stop)      :: 13 of 104
            Pseudo Genes (multiple problems)  :: 13 of 104
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP090631.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..13636
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /isolate="KpBO_TO1"
                     /isolation_source="Rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="unnamed2"
                     /geo_loc_name="Italy"
                     /lat_lon="45.0703 N 7.6869 E"
                     /collection_date="2021-04-23"
                     /collected_by="Turin"
                     /genotype="ST512"
     gene            join(13204..13636,1..125)
                     /locus_tag="L0105_RS27665"
                     /old_locus_tag="L0105_27665"
     CDS             join(13204..13636,1..125)
                     /locus_tag="L0105_RS27665"
                     /old_locus_tag="L0105_27665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001217881.1"
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="recombinase family protein"
     gene            359..913
                     /gene="aac(6')-Ib"
                     /locus_tag="L0105_RS27670"
                     /old_locus_tag="L0105_27670"
     ARG             360..910
                     /name="aac(6')-Ib"
                     /gene="aac(6')-Ib"
                     /gene_name="AAC(6')-Ib family aminoglycoside
                     6'-N-acetyltransferase"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            983..>1198
                     /locus_tag="L0105_RS27675"
                     /old_locus_tag="L0105_27675"
                     /pseudo=""
     CDS             983..>1198
                     /locus_tag="L0105_RS27675"
                     /old_locus_tag="L0105_27675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001424636.1"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /name="nucleotidyltransferase domain-containing protein"
     gene            1264..1968
                     /locus_tag="L0105_RS27680"
                     /old_locus_tag="L0105_27680"
     CDS             1264..1968
                     /locus_tag="L0105_RS27680"
                     /old_locus_tag="L0105_27680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_004217321.1"
                     /translation="MNPFKGRHFQRDIIRWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            <2023..2193
                     /locus_tag="L0105_RS27685"
                     /old_locus_tag="L0105_27685"
                     /pseudo=""
     CDS             <2023..2193
                     /locus_tag="L0105_RS27685"
                     /old_locus_tag="L0105_27685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /name="serine hydrolase"
     gene            <2341..2925
                     /locus_tag="L0105_RS27690"
                     /old_locus_tag="L0105_27690"
                     /pseudo=""
     CDS             <2341..2925
                     /locus_tag="L0105_RS27690"
                     /old_locus_tag="L0105_27690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]; GO:0043022 - ribosome binding
                     [Evidence IEA]; GO:0003723 - RNA binding [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3/pyocin S6 family cytotoxin"
                     /name="colicin E3/pyocin S6 family cytotoxin"
     gene            2935..3192
                     /locus_tag="L0105_RS27695"
                     /old_locus_tag="L0105_27695"
     CDS             2935..3192
                     /locus_tag="L0105_RS27695"
                     /old_locus_tag="L0105_27695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            3277..3426
                     /locus_tag="L0105_RS27700"
                     /old_locus_tag="L0105_27700"
     CDS             3277..3426
                     /locus_tag="L0105_RS27700"
                     /old_locus_tag="L0105_27700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            4907..6871
                     /locus_tag="L0105_RS27705"
                     /old_locus_tag="L0105_27705"
     CDS             4907..6871
                     /locus_tag="L0105_RS27705"
                     /old_locus_tag="L0105_27705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            6871..7602
                     /locus_tag="L0105_RS27710"
                     /old_locus_tag="L0105_27710"
     CDS             6871..7602
                     /locus_tag="L0105_RS27710"
                     /old_locus_tag="L0105_27710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            7609..8139
                     /locus_tag="L0105_RS27715"
                     /old_locus_tag="L0105_27715"
     CDS             7609..8139
                     /locus_tag="L0105_RS27715"
                     /old_locus_tag="L0105_27715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(8167..8346)
                     /locus_tag="L0105_RS27720"
                     /old_locus_tag="L0105_27720"
     CDS             complement(8167..8346)
                     /locus_tag="L0105_RS27720"
                     /old_locus_tag="L0105_27720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            8415..8792
                     /locus_tag="L0105_RS27725"
                     /old_locus_tag="L0105_27725"
     CDS             8415..8792
                     /locus_tag="L0105_RS27725"
                     /old_locus_tag="L0105_27725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            complement(8854..9153)
                     /locus_tag="L0105_RS27730"
                     /old_locus_tag="L0105_27730"
     CDS             complement(8854..9153)
                     /locus_tag="L0105_RS27730"
                     /old_locus_tag="L0105_27730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(9143..9406)
                     /locus_tag="L0105_RS27735"
                     /old_locus_tag="L0105_27735"
     CDS             complement(9143..9406)
                     /locus_tag="L0105_RS27735"
                     /old_locus_tag="L0105_27735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            complement(9712..>10002)
                     /locus_tag="L0105_RS27740"
                     /old_locus_tag="L0105_27740"
                     /pseudo=""
     CDS             complement(9712..>10002)
                     /locus_tag="L0105_RS27740"
                     /old_locus_tag="L0105_27740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /name="Exc2 family lipoprotein"
     gene            complement(10037..13042)
                     /locus_tag="L0105_RS27745"
                     /old_locus_tag="L0105_27745"
     CDS             complement(10037..13042)
                     /locus_tag="L0105_RS27745"
                     /old_locus_tag="L0105_27745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /protein_id="WP_001143775.1"
                     /translation="MPVDFLTTEQVESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHDEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISQSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLGENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASDLVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQASVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGALGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
                     /name="Tn3-like element Tn3 family transposase"
     ARG             996..1252
                     /name="aadA15"
                     /gene="aadA15"
                     /gene_name="ANT(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="97.14"
                     /coverage="32.32"
     ARG             309..913
                     /name="AAC(6')-Ib10"
                     /gene="AAC(6')-Ib10"
                     /gene_name="AAC(6')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="98.97"
                     /coverage="99.01"
     Typing          complement(3530..4108)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          6872..7599
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.34e-150"
ORIGIN
        1 ccgtggacag gaacgtcgtg ctgacgcttc atcagaaggg cactggtgca acggaaattg
       61 ctcatcagct cagtattgcc cgctccacgg tttataaaat tcttgaagac gaaagggcct
      121 cgtgatacgc ctatttttat aggttaatgt catgataata atggtttctt agacgtcagg
      181 tggcactttt cggggaaaag tgcgcggaac ccctatttgt ttatttttct aaatacattc
      241 aaatatgtat ccgctcatga gacaataacc ctgataaatg cttcaataat attgaaaaag
      301 gaagagtatg agtattcaac atttccaaac aaagttaggc atcacaaagt acagcatcgt
      361 gaccaacagc aacgattccg tcacactgcg cctcatgact gagcatgacc ttgcgatgct
      421 ctatgagtgg ctaaatcgat ctcatatcgt cgagtggtgg ggcggagaag aagcacgccc
      481 gacacttgct gacgtacagg aacagtactt gccaagcgtt ttagcgcaag agtccgtcac
      541 tccatacatt gcaatgctga atggagagcc gattgggtat gcccagtcgt acgttgctct
      601 tggaagcggg gacggatggt gggaagaaga aaccgatcca ggagtacgcg gaatagacca
      661 gttactggcg aatgcatcac aactgggcaa aggcttggga accaagctgg ttcgagctct
      721 ggttgagttg ctgttcaatg atcccgaggt caccaagatc caaacggacc cgtcgccgag
      781 caacttgcga gcgatccgat gctacgagaa agcggggttt gagaggcaag gtaccgtaac
      841 caccccagat ggtccagccg tgtacatggt tcaaacacgc caggcattcg agcgaacacg
      901 cagtgttgcc taacccttcc atcgaggggg acgtccaagg gctggcgccc ttggccgccc
      961 ctcatgtcaa acgttaaaca tcatgaggga agcggtgatc gccgaagtat cgactcaact
     1021 atcagaggta gttggcgtca tcgagcgcca tctcgaaccg acgttgctgg ccgtacattt
     1081 gtacggctcc gcagtggatg gcggcctgaa gccacacagt gatattgatt tgctggttac
     1141 ggtgaccgta aggcttgatg aaacaacgcg gcgagctttg atcaacgacc ttttggaaac
     1201 ggcactgttg caaatagtcg gtggtgataa acttatcatc cccttttgct gatggagctg
     1261 cacatgaacc cattcaaagg ccggcatttt cagcgtgaca tcattcggtg ggccgtacgc
     1321 tggtactgca aatacggcat cagttaccgt gagctgcagg agatgctggc tgaacgcgga
     1381 gtgaatgtcg atcactccac gatttaccgc tgggttcagc gttatgcgcc tgaaatggaa
     1441 aaacggctgc gctggtactg gcgtaaccct tccgatcttt gcccgtggca catggatgaa
     1501 acctacgtga aggtcaatgg ccgctgggcg tatctgtacc gggccgtcga cagccggggc
     1561 cgcactgtcg atttttatct ctcctcccgt cgtaacagca aagctgcata ccggtttctg
     1621 ggtaaaatcc tcaacaacgt gaagaagtgg cagatcccgc gattcatcaa cacggataaa
     1681 gcgcccgcct atggtcgcgc gcttgctctg ctcaaacgcg aaggccggtg cccgtctgac
     1741 gttgaacacc gacagattaa gtaccggaac aacgtgattg aatgcgatca tggcaaactg
     1801 aaacggataa tcggcgccac gctgggattt aaatccatga agacggctta cgccaccatc
     1861 aaaggtattg aggtgatgcg tgcactacgc aaaggccagg cctcagcatt ttattatggt
     1921 gatcccctgg gcgaaatgcg cctggtaagc agagtttttg aaatgtaagg cctttgaata
     1981 agacaaaagg ctgcctcatc gctaactttg caacagtgcc ctgataaatc tggagccggt
     2041 gagcgtgggt ctcgcggtat cattgcagca ctggggccag atggtaagcc ctcccgtatc
     2101 gtagttatct acacgacggg gagtcaggca actatggatg aacgaaatag acagatcgct
     2161 gagataggtg cctcactgat taagcattgg taactgtcag accaagttta ctcatatata
     2221 ctttagattg atttaaaact tcatttttaa tttaaaagga tctaggtgaa gatccttttt
     2281 gataatctca tgaccaaaat cccttaacgt gagttttcgt tccactgagc gtcagacccc
     2341 gaagccgata aaaaggtaaa agaggcagag gcaaataaag atgattttgt gacttataac
     2401 ccgcctcatg aatatggctc cgggtggcag gatcaggttc gctatcttga taaggatatt
     2461 cagaatcaga atgagaaatt aaaagctgcc cagacatctt taaacgaaat gaatgaatcc
     2521 ttatccaggg ataaggctgc gctttccggg gcgatggaga gccggaaaca aaaggagaaa
     2581 aaagcgaagg atgcagaaaa taaattaaat gaggaaaaga aaaaacctcg taagggaact
     2641 aaagattacg gccatgatta ttttcctgat cccaagactg aagatattaa ggggttggga
     2701 gagttgaaag agggtaaacc taaaacccct aaacaaggtg gtggtggtaa gcgggcccga
     2761 tggtatggtg ataaaaagcg taaaatttat gaatgggatt cccagcacgg tgagcttgaa
     2821 gggtaccgcg ccagtgatgg cgaacacctc ggggcattcg atccaaaaac gggtaagcag
     2881 gttaaagggc cggatccaaa acgaaacatt aaaaaatatc tttaagaggt aaatatgggg
     2941 cttaaattac atattcattg gtttgataag aaaaccgaag agtttaaagg tggtgaatac
     3001 tcaaaagact tcggtgatga tggttctgtc attgaaagtc tggggatgcc tttaaaggat
     3061 aatattaata atggttggtt tgatgttgaa aaatcatggg tttcgatatt acagccacac
     3121 tttaaaaatg taatcgatat tagtaaattt gattactttg tatcctttgt ttaccgggat
     3181 ggtaactggt aagcaaaagt tatcaaggat gatttgaaat acagacttcc ggtgttcagg
     3241 gatgaatacc ggggttttta aatacaggga aggtatatga aaaaggtaaa ggttgttttt
     3301 ctttttatat tgattttttc aggctttctt ctggtcgcat gtcaggcaaa ctatatccgg
     3361 gatgttcagg gtggaacggt ggcaccatcg tcctcctctg aactgacggg gatcgcggtt
     3421 cagtagaaaa gatcaaagga tcttcttgag atcctttttt tctgcgcgta atcttttgcc
     3481 ctgtaaacga aaaaaccacc tggggaggtg gtttgatcga aggttaagtc agttggggaa
     3541 ctgcttaacc gtggtaactg gctttcgcag agcacagcaa ccaaatctgt ccttccagtg
     3601 tagccggact ttggcgcaca cttcaagagc aaccgcgtgt ttagctaaac aaatcctctg
     3661 cgaactccca gttaccaatg gctgctgcca gtggcgtttt gcgtgctttt ccgggttgga
     3721 ctcaagtgaa cagttaccgg ataaggcgca gcagtcgggc tgaacggggg gttcttgctt
     3781 acagcccagc ttggagcgaa cgacctacac cgagccgaga taccagagtg tgagctatga
     3841 gaaagcgcca cacttcccgc aagggagaaa ggcggaacag gtatccggga aacggcaggg
     3901 ttggaacagg agagcgcaag agggagcgat tcatcggaaa cggtgatgat ctttaagtcc
     3961 tgtcgggttt cgccactcct gactgattca tggttgagcc accggctccc acagatgcac
     4021 cgaaaaagcg tctgtttatg tgaactcagt caggagggcg gagcctatgg aaaaacgcca
     4081 cctgcgtggc cttgccgttt tgcctcacat gttagtcccc tgcttattca cggaatctgt
     4141 gggtaacttt gcatgtgtcc gcagcgcccg ccgcagtctc acggccggag cgtagcgacc
     4201 gagtgagcga ggaggcgcaa tttccccggc acctacaaga cggacaccgg acgcgctgat
     4261 gtggcatatt gtcccctgat taagtcttta tattccctga taataaatta ccaggatagg
     4321 tgaatcatat cggtttttcg ctgaacattt tacgttaacc tatctctgtt gcttttttct
     4381 ccttacggag aaatacaggt catccccgcg agggcgtggc tgacctcagg gggatatccc
     4441 ctgcttacgc tggctggacg ccaccgacgc acggtctctc cccctctttc tggctccgtc
     4501 cggctggacg ccggccacgc cagaaattca cccggccccc gtcaggctca cgcctgacca
     4561 cccacaaaaa tccacggtgc tggacgcacc tggcgaagca gcaaagctgc tcctgatttt
     4621 gcgggtggtc agccgctcgc tatggcgaac tctgacgggg gccggaacac cggaaaagac
     4681 cgcactgggg tgccgccttt tcctctcaca cgctggggcg tgctcgttgt tcctccgggg
     4741 ctgcgccttt tccgcatggg gcggaaagag gctggcctcc gtggtgaaag ctgaacgcaa
     4801 tcaccacgga cgtgaccgcc gccgccatgc cttggggcat gtccgcggct tgtgcagcgg
     4861 gggctgcaca tcacgccggc aaaccatcgt ctgaaggaga gagaacatgt ttaatacgga
     4921 ttcgcttgcc tggaagtggc acattccgga gctggcccgg cagatttatc cgtgggtcag
     4981 ctggctgtac caggagtatt acggtctggc cggggctttc ctagttatcg gcctgttttt
     5041 cggtctggct gaactttggg ccggacggat gcgttttgtg gggctgagtc ataaggagcg
     5101 acgggagtat gccgatcgct ataagcgcga taataaacgg ccagcgccat tttcggtgct
     5161 ggcctcgctg gattcgcccg ggcggatggt cagggcacgt cgacatgtct ggaactacgc
     5221 gtactggctg accggcgcgg ccggtctggc ccttctgggg gggctggttg tcgccgtgtt
     5281 tatcgagagc tggggagaaa ccgtcctgcg tccggacctc tacgcaaacg cagattatta
     5341 cctgctgcag ccggctaacc tgttcgggat tgcctggtgc gcgggcgggc tggctgtcgg
     5401 gattgtgttg gcgcggctgc tggcgttcct gctgcttgac ggtcattttg cggctgctga
     5461 cgaggcggtg aacgcgaaac tgaatcagga gagccggcgc agcagccagc ggacaggaga
     5521 gatgaccgac gtgcgccacc tgcatttcgg ggagccggta ccggttaatg cgctggccga
     5581 tttttcctcg gagcaggccc ggcaggagca ggcggtgttt ctgggtaagg atgagcaggg
     5641 caagccggtg ctggttccgc gtgatacctg gcgcaagacc aacattcaga tcctcggcct
     5701 gcccgggagc ggcaagagcg tgatggccac caacgcgctc attcgctgcg tacgcgattt
     5761 cggggacgcg gtggtgtact tcgaccccaa aggggacgca tgggcgccgc acgtcttccg
     5821 ggcgcactgt ccggacttca ccctgctgga tctgcggccg gggaaaccgg cgcagctgaa
     5881 tctgttccgc gatctcgacc agtacgcgct gaaaaacctg ctgattgccg ggcttaacct
     5941 gggcgagacc ggcgacgtgg cggaccacta ccgcatcagc gagcagaaag cggcgaagct
     6001 gattgcggag cagtttccgc agggggcaaa cattcagcag gtgctggcgg cggcgtacgc
     6061 gctgccggag gccctgaaaa aggacgtgaa ggggttgatc actaggctgg aaaacgtcgc
     6121 tgacctgagc gtcctgcaga cggacagtgg catcgatgtg gcggggatta tcaacggcgg
     6181 cggctgcctg tacgttatcg gctcgatgga cgacgaggcg gtgatccgtg tgcaaaaaat
     6241 gctgtttgcc cgctgcgcgc aaatcatcat tgcgcgggac gagttccggg agtggccaca
     6301 cgtcagcgtg atgctcgatg aaattaaata tctgctgtcg aagtatgtac tgaacgcact
     6361 ggggacgctg cgcagccggg actgcaatct gttgctcgcg caccagtcgc tgggcgattt
     6421 cgggcagtgc gggcaggatc tgcccgctga atttgtgaaa accacggtac tggataacac
     6481 gccgatccgc tggttttacc gggcggccag cctggagtcc gcgcagtggg cggcggggca
     6541 gaccggggaa atcagggtgg acgtggagcg ccgccgtgcc agccgggagg cggggaacgt
     6601 ggagcatatc agcggggaca gcttcatcca gaaggaggcg cggccgctgt ttgacgtgaa
     6661 caccctgcaa cacctgccgg acgggttcgc ggtcatgacc gggctgggtg tggcccggat
     6721 ggcgttcagc agtccgctgc gggttgagcg ccgggaaatc ccgttgcagc gtttcccggt
     6781 gctggcgaaa accgatcccc tggcggagtt ccggcccccg gccgacggcg gcgggccgaa
     6841 agcggatgat gattttgcgg ggatttactg atggcgctgg agctgtacaa cgtcagccac
     6901 gcgaaacgac aggcgcggaa cgcggagaaa acccggctga ccctgcgctg gttgcgggaa
     6961 gagctgtgtt ccacggcgga gctggttgcg cggcggctgg ggattgcggc ggtgcagccg
     7021 gtctaccgct tcctcgacag cctggtggcg aaagggctgc tggtccggac caaatatccg
     7081 gtggacggcc gtcaggtcag cgtgtggggg ctgacgccgc atggcgtggc gttctcgttc
     7141 gacgaggacg aaccgctggc ggatgttatt ccgtttcagc cgtcaagggt gtcggcagca
     7201 catctgccgc accggctggc cgtgcaatcc ctgcgccttg atatggaagc cagaggggcc
     7261 accggctggc gcattctgca ccgtctgagt cttaaaggca tgaaagtgcc ggacgccctg
     7321 gcggagctgg acggtaaaac ggtggcgttt gaggtggagc gcaccgtcaa gagccgtcgc
     7381 cggtatcagg aagtggtgtc cgggtatctg ttcaaccgca aagctaacgg catcgatgaa
     7441 atctggtaca tctgcccgga ccgggcgacg caggtcaggg tgcagcgggc aatcctgtcg
     7501 gtggatgaaa tcgtgaaccc acagaccggc gaggcccgca aaacggcaga gctggatcgt
     7561 gaacggttgt ttgcgtgctt taaatttatg acaacggagt gagggattat ggcgctgtac
     7621 atggtattta ttgaagacgc ggaggaccgg aacggcgagc gctgcatcat gccgaccagc
     7681 gagcatctgg aagatatggt ggtgctcgcc tggcagaccg gggcgtatgt tttctgtttt
     7741 gtcgaccggg cccagcatct ggcgatgatg aaatccatcg ggatgtatga cgagcggctc
     7801 aacagcgacg aaaaagccac gtactttttc actggtaaaa atccgcaatg ggaacggaac
     7861 aaacccacag gaatgaagct gtgtgattac ctctatcgca aggtggagcg gttcgccatc
     7921 gagaacggtg tgcaggtggt tgatgccggg aagtgctcac cggagcagat taacgcgatg
     7981 attgacgtgg tgagtgagcg gcacggggaa agcgcggtga acgagaagct gaaagcggag
     8041 ctgatgcggg aatataacag ccgctatttt aacgtgccgg tacctgaact gccggaggac
     8101 aaacctgccc gccggtggtg gccgttcggc aaaaaataaa tgccagcacc ggccatgccg
     8161 gtgctgttat tcctccccga gcttatcccg catcacctgc cagagtgttt ccgcatcctc
     8221 gtgtagccgc tcgcacatgt cggccggggt atccatatcc agctcattca gtttatcgag
     8281 caatagcagc gactgctcct taataaattt agccatattg agggctgttt tttcctgttt
     8341 tgtcatgatt ctttccttcc gggcatggtg tgcgcctgtc aggtatactg tctcaaaaat
     8401 agcggggtga gacaatggcg tgggtgacgg tgagacaggc gacggaactg acgggtaaag
     8461 cccgaagttc cctgtatcgg gatatggcga aaggccgcgt atcataccgt acggaagctg
     8521 atggcggccg ggtggtggat accagcgagc ttatccgggt gtacggtgag ttaagacagg
     8581 atgagactca cgagcgggac gagttgagac tgtcgggtga gactgaaaaa atggcctccg
     8641 acgcgttgat cgcggagata aaagcactca gggaggaggt ggccgggcta cggcaggaaa
     8701 tgcagtccat gagactgctg gaacacaaac cggagacagc agagaccccg gccggaacac
     8761 cgcgccggtg gtggccgtgg ggaaaacgct gacgcgctgt gcttgtccaa ccggcgacgg
     8821 ccacgcaatg aattgcgtcc ccgtcaccgg ttattagaga acaatatggg gattctggcg
     8881 ctggccgacc acggccagaa cccggacttt tctggtctgg tcatcaacat catagaggac
     8941 atgctgtccc atcagactga tccggcgaac gtcctcgcca tagcgtgagt ccacttcata
     9001 gagtcgcggg aagtcggcca gtttgtccgc cgcagcgaga acccggtcgg taacgttctg
     9061 cgcatcccac agggatgaat tttccgcgat atagtcaaac agcgtcgtta catcctcgat
     9121 ggctccctgc ttccattcca cgtcatacgg catcgcgcag ttcctgataa cggccatgca
     9181 ggcgctggcg gagttgttcc gtggtcatac ccggacgcgt gtcagcacgg gcggcggtca
     9241 ctttggcgcg aacctgatct tcatactctg cctgggccag ttcttcgtta gccagtcgct
     9301 gcaacagcgc agctttgtcc gggccacctt ccggcagtat gcggggcagg ctttcagcca
     9361 gttcccgaag aaagttggcg ttttcgtagt gtgtagtgtt gctcattgcg gagcctcccg
     9421 ggttaatgcg gcaatatgaa ggaagtttag cagggggcgg tctgaaagaa tatggtcgtg
     9481 tcagtcaggc tgatgaagca gaaagtcggt aaaaaagggc ttacggcatc cattttacgt
     9541 caaaacatat gccatgcagt tgcgtgcata ggcatgcatt aggataaaat ttatcgggcg
     9601 cgtttccggc agttttccgg gggggttgtt gcctgtttta tcccgtagcc gccggaaacg
     9661 ccctgagccc gtctgagcgg tgcgcgtaat gacgcgttat ggtaaatcca cttactgtct
     9721 gccttcatag ccatcgagat aaacagctga aatggtgtca gccagtagcc ttgatttttt
     9781 cggtgtgagg tctttgctgc ggtaatcggt acccgcaaat tgtgttgtgc cttggagtga
     9841 gtttaaaaat tcctgactgt gaaactgctg aatgcgttgc tgcacatcac tccgtgattt
     9901 tccggtcgct ttatcctttg cgcccatatc ccagaactgc cggaaaaaag gcaccatcat
     9961 tcgtgttgtg tcagctttct gggtggaaaa attgggatca aaaggggtct gacgctcagt
    10021 ggaacgaaaa ctcacgttaa gcaacgtttt ctgcctctga cgcctctttt aatggtctca
    10081 gatgaccttt ggtcaccagt tctgccagcg tgaaggaata atggccgagc atattgatat
    10141 gtccgtggca aagcggggag aggcgtgcga tatcttcatc attcagtgtt tcaccctgcg
    10201 cccggagatg atccagagct gcctgcatat aaatagtgtt ccataacacg acggcgttag
    10261 tgaccagccc cagagctccc aactgatctt cctgaccgtc ggtatatcgt tttcttatct
    10321 cacctttttg accgtgacag atggctctgg caactgcatg acggctttct ccccgattaa
    10381 gctgggtcag aatgcgccgg cggtaatctt catcatcaat ataattaagc agatacagcg
    10441 ttttgttgat gcgccccact tcaatgattg cctgagtcag tccggaggga cgttcacttt
    10501 tcagcaatga acggaccagc actgaggcct gtactttgcc cagcttcagg gagcctgcgg
    10561 tccggatcat ttcgtcccac tgaaggacta tttttcgggg atctgattgc cctctggcaa
    10621 tatcattcag cacgccatag tcggcatcat ggtccattcg ccagaaaacc gaagcaccgg
    10681 catcagccag gcgtggagaa aactggtatc ccagcagcca gaaaaggcca aagacaagat
    10741 cgctggcacc tgccgtatcg gtcataattt cggttggatt cagcccggtc tcctgttcca
    10801 gaaggccttc cagcacaaag atagagtccc tcagcgtccc cggtataacg atgccatgaa
    10861 agccggaata ctgatcggac acaaagttgt accaggtgat ccctctgtta ttaccaaagt
    10921 atttgcggtt cggtccggca ttgattgttc tgactggcgt aacaaagcgc attccatctg
    10981 cagatgccac ttctcctcca ccccatatct gtgccagtgg cagcgttgcc tgaaaatcaa
    11041 ccagtctggc attagcgctg gtgatagttt cagcccgcag atagttcgct tttgtccagt
    11101 tcagccggtg tcgggtcagt gcaggaacat ttgatctgat cagtggttcc agaccgatat
    11161 tgcaggcttc agccatcagc acggcgctga tgctgacggg cagatcatca actctggcac
    11221 tggcttcact ggcatggaaa aactcatcag caaatccggt atgggcgtta atttcgagca
    11281 gcaactccgt taaatccacc ggagggagca gatcactgat cattttgctc agtcgtttca
    11341 gactgtccgg ctcatcaaga ctggcgaggg gagaaattgt caaccggggc ttcgggccag
    11401 aaacatcgag ttcgacagcc tcattttcgc caagacgtgc agcaacctgt ctgtaacgac
    11461 tatcaagctg atggcccaga gattttattg cttcctgcgg gtctgtcggg tgccccaaag
    11521 aacgataaac cttaatccga tttgcctgcc agtcagcacc ctgtagtaat cttgcacgag
    11581 gatctcccca ccggttactg ccggtaacgt agacatccct ccgtctcaga ctatcctgca
    11641 gtttactgag aaagcagagc gtgtatcccc ttcgggtgat atgtttttcc ttgttaatca
    11701 ccagccgttt ccatgactga ctgatgattt ccgttggtgc gtcgtcaaaa aactgccgcc
    11761 gtgagctgaa ctcccggctg aggtagtcac aggcattcag agtggtaacc ccggcaggtg
    11821 cggatgaaaa tttaacggta ttcagcagat ggggcaggaa acgacgaacg cgcccgtact
    11881 gctccaccat ttcgtcatga aaattatcgt ctgagggccg ggcaatttca cggacaagcg
    11941 tgatgatttc agccagcttt tgcctaggga tgtagctgaa cacctcagca cgaatcgatt
    12001 cgtccggtgt ttcttctttc agcaagtacg aacatgcgct ggcgagcgcc aatgcagatt
    12061 tatccagatc cttcagcgag cggagccgtt ttttctgccc aatctttctg gcgtcacgga
    12121 tgataacggc cagcatggcg tccagaacgt ccagtgcatc atccagcgcc agcgtttccc
    12181 atgcaaggac aaaggcaacc agaaccgcca tccttttctg cggtgacatc ctggcaatat
    12241 tgaacaccga agtcatacca gcataacgtg cgagattttt caggcgcaca gccgggagtg
    12301 tactcaggtt ttcagcatgc aggccaaaat cgttcagagt tttccagcgt tcaattgctt
    12361 cattaaacgc cggaccactg atggtcacag ggcctttttt cagtgattcc agtaaagaca
    12421 ggcggctgca atcagttggc cccagcagca tctccagctg tgaacgctgt tcggctgacg
    12481 gtatcagtgc cagtttgttc cacaggcgca acgtcgcctt ttcccttacc tctgaaatca
    12541 accgggtcag cgtggtggct ccggggagaa taatacgatg ttgcataagc caccctgtcg
    12601 ccaggtcgaa aagcaggcca ggacgttcgt tgcttatcca gctccgggta tataaaagac
    12661 gggtaaggcg aaatgtccag ggccaggcaa attcacgata ctgatagtgc tgacgtatca
    12721 gcgctgcatg ctcacggcgg gtattttccc tctgaccgta ttctgcaaga acggtgatat
    12781 cacgaatccc gagctgtctg gcggtaaaat gccggacgcc ggaaggaata tgattcatgt
    12841 cagtaagaaa agtgcccaga aaacgcacac acccgatttg cagggcaata ccaagtcgat
    12901 tgtgatcacc ccggcttttc ccgataaatt ctttatccgc ttcatcaaga tgaaaataac
    12961 gcgccagctg aagttcatcg ggttcgccag tgaacctgcc ataactctca acctgctcag
    13021 tggtcaaaaa atcaacgggc atatcggcct ccctgcctga cggctttttt aacacaactg
    13081 caaccgttcg aaatattata aattatcaga catagtaaaa cggcttcgtt tgagtgtcca
    13141 ttaaatcgtc attttggcat aatagacaca tcgtgtctga tattcgattt aaggtacatt
    13201 tttatgcgaa tttttggtta tgcgcgggtc tcaaccagcc agcagtccct cgatattcag
    13261 atcagagcgc tcaaagatgc aggggtaaaa gctaaccgca tctttaccga caaggcatcc
    13321 ggcagttcaa cagatcggga agggctggat ttgctgagga tgaaggtgga ggaaggtgat
    13381 gtcattctgg tgaagaagct cgaccgtctt ggccgcgaca ccgccgacat gatccaactg
    13441 ataaaagagt ttgatgctca gggtgtagcg gttcggttta ttgacgacgg gatcagtacc
    13501 gacggtgata tggggcaaat ggtggtcacc atcctgtcgg ctgtggcaca ggctgaacgc
    13561 cggaggatcc tagagcgcac gaatgagggc cgacaggaag caaagctgaa aggaatcaaa
    13621 tttggccgca ggcgta
//
