LOCUS       NZ_CP090628            13636 bp    DNA     circular CON 08-DEC-2023
DEFINITION  Klebsiella pneumoniae isolate KpBO_TO3 plasmid unnamed2, complete
            sequence.
ACCESSION   NZ_CP090628
VERSION     NZ_CP090628.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN24648677
            Assembly: GCF_021485005.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 13636)
  AUTHORS   Gaibani,P.
  TITLE     In vivo emergence of Imipenem/relebactam resistance in KPC-producing
            Klebsiella pneumoniae mediated by increased blaKPC copy number and
            porins
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 13636)
  AUTHORS   Gaibani,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JAN-2022) Microbiology, Policlinico
            Sant'Orsola-Malpighi, Via Massarenti 9, Bologna, BO 40138, Italy
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 20x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina iSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/08/2023 10:43:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,575
            CDSs (total)                      :: 5,452
            Genes (coding)                    :: 5,343
            CDSs (with protein)               :: 5,343
            Genes (RNA)                       :: 123
            rRNAs                             :: 9, 7, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 7, 8 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 53 of 109
            Pseudo Genes (incomplete)         :: 57 of 109
            Pseudo Genes (internal stop)      :: 13 of 109
            Pseudo Genes (multiple problems)  :: 13 of 109
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP090628.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..13636
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /isolate="KpBO_TO3"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="unnamed2"
                     /geo_loc_name="Italy"
                     /lat_lon="45.0703 N 7.6869 E"
                     /collection_date="2021-07-01"
                     /collected_by="Turin"
                     /genotype="ST512"
     gene            join(13246..13636,1..314)
                     /locus_tag="L0104_RS27675"
                     /old_locus_tag="L0104_27675"
     CDS             join(13246..13636,1..314)
                     /locus_tag="L0104_RS27675"
                     /old_locus_tag="L0104_27675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_004217321.1"
                     /translation="MNPFKGRHFQRDIIRWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            <369..539
                     /locus_tag="L0104_RS27680"
                     /old_locus_tag="L0104_27680"
                     /pseudo=""
     CDS             <369..539
                     /locus_tag="L0104_RS27680"
                     /old_locus_tag="L0104_27680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /name="serine hydrolase"
     gene            <687..1271
                     /locus_tag="L0104_RS27685"
                     /old_locus_tag="L0104_27685"
                     /pseudo=""
     CDS             <687..1271
                     /locus_tag="L0104_RS27685"
                     /old_locus_tag="L0104_27685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]; GO:0043022 - ribosome binding
                     [Evidence IEA]; GO:0003723 - RNA binding [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3/pyocin S6 family cytotoxin"
                     /name="colicin E3/pyocin S6 family cytotoxin"
     gene            1281..1538
                     /locus_tag="L0104_RS27690"
                     /old_locus_tag="L0104_27690"
     CDS             1281..1538
                     /locus_tag="L0104_RS27690"
                     /old_locus_tag="L0104_27690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            1623..1772
                     /locus_tag="L0104_RS27695"
                     /old_locus_tag="L0104_27695"
     CDS             1623..1772
                     /locus_tag="L0104_RS27695"
                     /old_locus_tag="L0104_27695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            3253..5217
                     /locus_tag="L0104_RS27700"
                     /old_locus_tag="L0104_27700"
     CDS             3253..5217
                     /locus_tag="L0104_RS27700"
                     /old_locus_tag="L0104_27700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            5217..5948
                     /locus_tag="L0104_RS27705"
                     /old_locus_tag="L0104_27705"
     CDS             5217..5948
                     /locus_tag="L0104_RS27705"
                     /old_locus_tag="L0104_27705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            5955..6485
                     /locus_tag="L0104_RS27710"
                     /old_locus_tag="L0104_27710"
     CDS             5955..6485
                     /locus_tag="L0104_RS27710"
                     /old_locus_tag="L0104_27710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(6513..6692)
                     /locus_tag="L0104_RS27715"
                     /old_locus_tag="L0104_27715"
     CDS             complement(6513..6692)
                     /locus_tag="L0104_RS27715"
                     /old_locus_tag="L0104_27715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            6761..7138
                     /locus_tag="L0104_RS27720"
                     /old_locus_tag="L0104_27720"
     CDS             6761..7138
                     /locus_tag="L0104_RS27720"
                     /old_locus_tag="L0104_27720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            complement(7200..7499)
                     /locus_tag="L0104_RS27725"
                     /old_locus_tag="L0104_27725"
     CDS             complement(7200..7499)
                     /locus_tag="L0104_RS27725"
                     /old_locus_tag="L0104_27725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(7489..7752)
                     /locus_tag="L0104_RS27730"
                     /old_locus_tag="L0104_27730"
     CDS             complement(7489..7752)
                     /locus_tag="L0104_RS27730"
                     /old_locus_tag="L0104_27730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            complement(8058..>8348)
                     /locus_tag="L0104_RS27735"
                     /old_locus_tag="L0104_27735"
                     /pseudo=""
     CDS             complement(8058..>8348)
                     /locus_tag="L0104_RS27735"
                     /old_locus_tag="L0104_27735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /name="Exc2 family lipoprotein"
     gene            complement(8383..11388)
                     /locus_tag="L0104_RS27740"
                     /old_locus_tag="L0104_27740"
     CDS             complement(8383..11388)
                     /locus_tag="L0104_RS27740"
                     /old_locus_tag="L0104_27740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /protein_id="WP_001143775.1"
                     /translation="MPVDFLTTEQVESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHDEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISQSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLGENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASDLVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQASVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGALGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
                     /name="Tn3-like element Tn3 family transposase"
     gene            11550..12107
                     /locus_tag="L0104_RS27745"
                     /old_locus_tag="L0104_27745"
     CDS             11550..12107
                     /locus_tag="L0104_RS27745"
                     /old_locus_tag="L0104_27745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001217881.1"
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="recombinase family protein"
     gene            12341..12895
                     /gene="aac(6')-Ib"
                     /locus_tag="L0104_RS27750"
                     /old_locus_tag="L0104_27750"
     ARG             12342..12892
                     /name="aac(6')-Ib"
                     /gene="aac(6')-Ib"
                     /gene_name="AAC(6')-Ib family aminoglycoside
                     6'-N-acetyltransferase"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            12965..>13180
                     /locus_tag="L0104_RS27755"
                     /old_locus_tag="L0104_27755"
                     /pseudo=""
     CDS             12965..>13180
                     /locus_tag="L0104_RS27755"
                     /old_locus_tag="L0104_27755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001424636.1"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /name="nucleotidyltransferase domain-containing protein"
     ARG             12978..13234
                     /name="aadA15"
                     /gene="aadA15"
                     /gene_name="ANT(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="97.14"
                     /coverage="32.32"
     ARG             12291..12895
                     /name="AAC(6')-Ib10"
                     /gene="AAC(6')-Ib10"
                     /gene_name="AAC(6')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="98.97"
                     /coverage="99.01"
     Typing          complement(1876..2454)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          5218..5945
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.34e-150"
ORIGIN
        1 tcccgcgatt catcaacacg gataaagcgc ccgcctatgg tcgcgcgctt gctctgctca
       61 aacgcgaagg ccggtgcccg tctgacgttg aacaccgaca gattaagtac cggaacaacg
      121 tgattgaatg cgatcatggc aaactgaaac ggataatcgg cgccacgctg ggatttaaat
      181 ccatgaagac ggcttacgcc accatcaaag gtattgaggt gatgcgtgca ctacgcaaag
      241 gccaggcctc agcattttat tatggtgatc ccctgggcga aatgcgcctg gtaagcagag
      301 tttttgaaat gtaaggcctt tgaataagac aaaaggctgc ctcatcgcta actttgcaac
      361 agtgccctga taaatctgga gccggtgagc gtgggtctcg cggtatcatt gcagcactgg
      421 ggccagatgg taagccctcc cgtatcgtag ttatctacac gacggggagt caggcaacta
      481 tggatgaacg aaatagacag atcgctgaga taggtgcctc actgattaag cattggtaac
      541 tgtcagacca agtttactca tatatacttt agattgattt aaaacttcat ttttaattta
      601 aaaggatcta ggtgaagatc ctttttgata atctcatgac caaaatccct taacgtgagt
      661 tttcgttcca ctgagcgtca gaccccgaag ccgataaaaa ggtaaaagag gcagaggcaa
      721 ataaagatga ttttgtgact tataacccgc ctcatgaata tggctccggg tggcaggatc
      781 aggttcgcta tcttgataag gatattcaga atcagaatga gaaattaaaa gctgcccaga
      841 catctttaaa cgaaatgaat gaatccttat ccagggataa ggctgcgctt tccggggcga
      901 tggagagccg gaaacaaaag gagaaaaaag cgaaggatgc agaaaataaa ttaaatgagg
      961 aaaagaaaaa acctcgtaag ggaactaaag attacggcca tgattatttt cctgatccca
     1021 agactgaaga tattaagggg ttgggagagt tgaaagaggg taaacctaaa acccctaaac
     1081 aaggtggtgg tggtaagcgg gcccgatggt atggtgataa aaagcgtaaa atttatgaat
     1141 gggattccca gcacggtgag cttgaagggt accgcgccag tgatggcgaa cacctcgggg
     1201 cattcgatcc aaaaacgggt aagcaggtta aagggccgga tccaaaacga aacattaaaa
     1261 aatatcttta agaggtaaat atggggctta aattacatat tcattggttt gataagaaaa
     1321 ccgaagagtt taaaggtggt gaatactcaa aagacttcgg tgatgatggt tctgtcattg
     1381 aaagtctggg gatgccttta aaggataata ttaataatgg ttggtttgat gttgaaaaat
     1441 catgggtttc gatattacag ccacacttta aaaatgtaat cgatattagt aaatttgatt
     1501 actttgtatc ctttgtttac cgggatggta actggtaagc aaaagttatc aaggatgatt
     1561 tgaaatacag acttccggtg ttcagggatg aataccgggg tttttaaata cagggaaggt
     1621 atatgaaaaa ggtaaaggtt gtttttcttt ttatattgat tttttcaggc tttcttctgg
     1681 tcgcatgtca ggcaaactat atccgggatg ttcagggtgg aacggtggca ccatcgtcct
     1741 cctctgaact gacggggatc gcggttcagt agaaaagatc aaaggatctt cttgagatcc
     1801 tttttttctg cgcgtaatct tttgccctgt aaacgaaaaa accacctggg gaggtggttt
     1861 gatcgaaggt taagtcagtt ggggaactgc ttaaccgtgg taactggctt tcgcagagca
     1921 cagcaaccaa atctgtcctt ccagtgtagc cggactttgg cgcacacttc aagagcaacc
     1981 gcgtgtttag ctaaacaaat cctctgcgaa ctcccagtta ccaatggctg ctgccagtgg
     2041 cgttttgcgt gcttttccgg gttggactca agtgaacagt taccggataa ggcgcagcag
     2101 tcgggctgaa cggggggttc ttgcttacag cccagcttgg agcgaacgac ctacaccgag
     2161 ccgagatacc agagtgtgag ctatgagaaa gcgccacact tcccgcaagg gagaaaggcg
     2221 gaacaggtat ccgggaaacg gcagggttgg aacaggagag cgcaagaggg agcgattcat
     2281 cggaaacggt gatgatcttt aagtcctgtc gggtttcgcc actcctgact gattcatggt
     2341 tgagccaccg gctcccacag atgcaccgaa aaagcgtctg tttatgtgaa ctcagtcagg
     2401 agggcggagc ctatggaaaa acgccacctg cgtggccttg ccgttttgcc tcacatgtta
     2461 gtcccctgct tattcacgga atctgtgggt aactttgcat gtgtccgcag cgcccgccgc
     2521 agtctcacgg ccggagcgta gcgaccgagt gagcgaggag gcgcaatttc cccggcacct
     2581 acaagacgga caccggacgc gctgatgtgg catattgtcc cctgattaag tctttatatt
     2641 ccctgataat aaattaccag gataggtgaa tcatatcggt ttttcgctga acattttacg
     2701 ttaacctatc tctgttgctt ttttctcctt acggagaaat acaggtcatc cccgcgaggg
     2761 cgtggctgac ctcaggggga tatcccctgc ttacgctggc tggacgccac cgacgcacgg
     2821 tctctccccc tctttctggc tccgtccggc tggacgccgg ccacgccaga aattcacccg
     2881 gcccccgtca ggctcacgcc tgaccaccca caaaaatcca cggtgctgga cgcacctggc
     2941 gaagcagcaa agctgctcct gattttgcgg gtggtcagcc gctcgctatg gcgaactctg
     3001 acgggggccg gaacaccgga aaagaccgca ctggggtgcc gccttttcct ctcacacgct
     3061 ggggcgtgct cgttgttcct ccggggctgc gccttttccg catggggcgg aaagaggctg
     3121 gcctccgtgg tgaaagctga acgcaatcac cacggacgtg accgccgccg ccatgccttg
     3181 gggcatgtcc gcggcttgtg cagcgggggc tgcacatcac gccggcaaac catcgtctga
     3241 aggagagaga acatgtttaa tacggattcg cttgcctgga agtggcacat tccggagctg
     3301 gcccggcaga tttatccgtg ggtcagctgg ctgtaccagg agtattacgg tctggccggg
     3361 gctttcctag ttatcggcct gtttttcggt ctggctgaac tttgggccgg acggatgcgt
     3421 tttgtggggc tgagtcataa ggagcgacgg gagtatgccg atcgctataa gcgcgataat
     3481 aaacggccag cgccattttc ggtgctggcc tcgctggatt cgcccgggcg gatggtcagg
     3541 gcacgtcgac atgtctggaa ctacgcgtac tggctgaccg gcgcggccgg tctggccctt
     3601 ctgggggggc tggttgtcgc cgtgtttatc gagagctggg gagaaaccgt cctgcgtccg
     3661 gacctctacg caaacgcaga ttattacctg ctgcagccgg ctaacctgtt cgggattgcc
     3721 tggtgcgcgg gcgggctggc tgtcgggatt gtgttggcgc ggctgctggc gttcctgctg
     3781 cttgacggtc attttgcggc tgctgacgag gcggtgaacg cgaaactgaa tcaggagagc
     3841 cggcgcagca gccagcggac aggagagatg accgacgtgc gccacctgca tttcggggag
     3901 ccggtaccgg ttaatgcgct ggccgatttt tcctcggagc aggcccggca ggagcaggcg
     3961 gtgtttctgg gtaaggatga gcagggcaag ccggtgctgg ttccgcgtga tacctggcgc
     4021 aagaccaaca ttcagatcct cggcctgccc gggagcggca agagcgtgat ggccaccaac
     4081 gcgctcattc gctgcgtacg cgatttcggg gacgcggtgg tgtacttcga ccccaaaggg
     4141 gacgcatggg cgccgcacgt cttccgggcg cactgtccgg acttcaccct gctggatctg
     4201 cggccgggga aaccggcgca gctgaatctg ttccgcgatc tcgaccagta cgcgctgaaa
     4261 aacctgctga ttgccgggct taacctgggc gagaccggcg acgtggcgga ccactaccgc
     4321 atcagcgagc agaaagcggc gaagctgatt gcggagcagt ttccgcaggg ggcaaacatt
     4381 cagcaggtgc tggcggcggc gtacgcgctg ccggaggccc tgaaaaagga cgtgaagggg
     4441 ttgatcacta ggctggaaaa cgtcgctgac ctgagcgtcc tgcagacgga cagtggcatc
     4501 gatgtggcgg ggattatcaa cggcggcggc tgcctgtacg ttatcggctc gatggacgac
     4561 gaggcggtga tccgtgtgca aaaaatgctg tttgcccgct gcgcgcaaat catcattgcg
     4621 cgggacgagt tccgggagtg gccacacgtc agcgtgatgc tcgatgaaat taaatatctg
     4681 ctgtcgaagt atgtactgaa cgcactgggg acgctgcgca gccgggactg caatctgttg
     4741 ctcgcgcacc agtcgctggg cgatttcggg cagtgcgggc aggatctgcc cgctgaattt
     4801 gtgaaaacca cggtactgga taacacgccg atccgctggt tttaccgggc ggccagcctg
     4861 gagtccgcgc agtgggcggc ggggcagacc ggggaaatca gggtggacgt ggagcgccgc
     4921 cgtgccagcc gggaggcggg gaacgtggag catatcagcg gggacagctt catccagaag
     4981 gaggcgcggc cgctgtttga cgtgaacacc ctgcaacacc tgccggacgg gttcgcggtc
     5041 atgaccgggc tgggtgtggc ccggatggcg ttcagcagtc cgctgcgggt tgagcgccgg
     5101 gaaatcccgt tgcagcgttt cccggtgctg gcgaaaaccg atcccctggc ggagttccgg
     5161 cccccggccg acggcggcgg gccgaaagcg gatgatgatt ttgcggggat ttactgatgg
     5221 cgctggagct gtacaacgtc agccacgcga aacgacaggc gcggaacgcg gagaaaaccc
     5281 ggctgaccct gcgctggttg cgggaagagc tgtgttccac ggcggagctg gttgcgcggc
     5341 ggctggggat tgcggcggtg cagccggtct accgcttcct cgacagcctg gtggcgaaag
     5401 ggctgctggt ccggaccaaa tatccggtgg acggccgtca ggtcagcgtg tgggggctga
     5461 cgccgcatgg cgtggcgttc tcgttcgacg aggacgaacc gctggcggat gttattccgt
     5521 ttcagccgtc aagggtgtcg gcagcacatc tgccgcaccg gctggccgtg caatccctgc
     5581 gccttgatat ggaagccaga ggggccaccg gctggcgcat tctgcaccgt ctgagtctta
     5641 aaggcatgaa agtgccggac gccctggcgg agctggacgg taaaacggtg gcgtttgagg
     5701 tggagcgcac cgtcaagagc cgtcgccggt atcaggaagt ggtgtccggg tatctgttca
     5761 accgcaaagc taacggcatc gatgaaatct ggtacatctg cccggaccgg gcgacgcagg
     5821 tcagggtgca gcgggcaatc ctgtcggtgg atgaaatcgt gaacccacag accggcgagg
     5881 cccgcaaaac ggcagagctg gatcgtgaac ggttgtttgc gtgctttaaa tttatgacaa
     5941 cggagtgagg gattatggcg ctgtacatgg tatttattga agacgcggag gaccggaacg
     6001 gcgagcgctg catcatgccg accagcgagc atctggaaga tatggtggtg ctcgcctggc
     6061 agaccggggc gtatgttttc tgttttgtcg accgggccca gcatctggcg atgatgaaat
     6121 ccatcgggat gtatgacgag cggctcaaca gcgacgaaaa agccacgtac tttttcactg
     6181 gtaaaaatcc gcaatgggaa cggaacaaac ccacaggaat gaagctgtgt gattacctct
     6241 atcgcaaggt ggagcggttc gccatcgaga acggtgtgca ggtggttgat gccgggaagt
     6301 gctcaccgga gcagattaac gcgatgattg acgtggtgag tgagcggcac ggggaaagcg
     6361 cggtgaacga gaagctgaaa gcggagctga tgcgggaata taacagccgc tattttaacg
     6421 tgccggtacc tgaactgccg gaggacaaac ctgcccgccg gtggtggccg ttcggcaaaa
     6481 aataaatgcc agcaccggcc atgccggtgc tgttattcct ccccgagctt atcccgcatc
     6541 acctgccaga gtgtttccgc atcctcgtgt agccgctcgc acatgtcggc cggggtatcc
     6601 atatccagct cattcagttt atcgagcaat agcagcgact gctccttaat aaatttagcc
     6661 atattgaggg ctgttttttc ctgttttgtc atgattcttt ccttccgggc atggtgtgcg
     6721 cctgtcaggt atactgtctc aaaaatagcg gggtgagaca atggcgtggg tgacggtgag
     6781 acaggcgacg gaactgacgg gtaaagcccg aagttccctg tatcgggata tggcgaaagg
     6841 ccgcgtatca taccgtacgg aagctgatgg cggccgggtg gtggatacca gcgagcttat
     6901 ccgggtgtac ggtgagttaa gacaggatga gactcacgag cgggacgagt tgagactgtc
     6961 gggtgagact gaaaaaatgg cctccgacgc gttgatcgcg gagataaaag cactcaggga
     7021 ggaggtggcc gggctacggc aggaaatgca gtccatgaga ctgctggaac acaaaccgga
     7081 gacagcagag accccggccg gaacaccgcg ccggtggtgg ccgtggggaa aacgctgacg
     7141 cgctgtgctt gtccaaccgg cgacggccac gcaatgaatt gcgtccccgt caccggttat
     7201 tagagaacaa tatggggatt ctggcgctgg ccgaccacgg ccagaacccg gacttttctg
     7261 gtctggtcat caacatcata gaggacatgc tgtcccatca gactgatccg gcgaacgtcc
     7321 tcgccatagc gtgagtccac ttcatagagt cgcgggaagt cggccagttt gtccgccgca
     7381 gcgagaaccc ggtcggtaac gttctgcgca tcccacaggg atgaattttc cgcgatatag
     7441 tcaaacagcg tcgttacatc ctcgatggct ccctgcttcc attccacgtc atacggcatc
     7501 gcgcagttcc tgataacggc catgcaggcg ctggcggagt tgttccgtgg tcatacccgg
     7561 acgcgtgtca gcacgggcgg cggtcacttt ggcgcgaacc tgatcttcat actctgcctg
     7621 ggccagttct tcgttagcca gtcgctgcaa cagcgcagct ttgtccgggc caccttccgg
     7681 cagtatgcgg ggcaggcttt cagccagttc ccgaagaaag ttggcgtttt cgtagtgtgt
     7741 agtgttgctc attgcggagc ctcccgggtt aatgcggcaa tatgaaggaa gtttagcagg
     7801 gggcggtctg aaagaatatg gtcgtgtcag tcaggctgat gaagcagaaa gtcggtaaaa
     7861 aagggcttac ggcatccatt ttacgtcaaa acatatgcca tgcagttgcg tgcataggca
     7921 tgcattagga taaaatttat cgggcgcgtt tccggcagtt ttccgggggg gttgttgcct
     7981 gttttatccc gtagccgccg gaaacgccct gagcccgtct gagcggtgcg cgtaatgacg
     8041 cgttatggta aatccactta ctgtctgcct tcatagccat cgagataaac agctgaaatg
     8101 gtgtcagcca gtagccttga ttttttcggt gtgaggtctt tgctgcggta atcggtaccc
     8161 gcaaattgtg ttgtgccttg gagtgagttt aaaaattcct gactgtgaaa ctgctgaatg
     8221 cgttgctgca catcactccg tgattttccg gtcgctttat cctttgcgcc catatcccag
     8281 aactgccgga aaaaaggcac catcattcgt gttgtgtcag ctttctgggt ggaaaaattg
     8341 ggatcaaaag gggtctgacg ctcagtggaa cgaaaactca cgttaagcaa cgttttctgc
     8401 ctctgacgcc tcttttaatg gtctcagatg acctttggtc accagttctg ccagcgtgaa
     8461 ggaataatgg ccgagcatat tgatatgtcc gtggcaaagc ggggagaggc gtgcgatatc
     8521 ttcatcattc agtgtttcac cctgcgcccg gagatgatcc agagctgcct gcatataaat
     8581 agtgttccat aacacgacgg cgttagtgac cagccccaga gctcccaact gatcttcctg
     8641 accgtcggta tatcgttttc ttatctcacc tttttgaccg tgacagatgg ctctggcaac
     8701 tgcatgacgg ctttctcccc gattaagctg ggtcagaatg cgccggcggt aatcttcatc
     8761 atcaatataa ttaagcagat acagcgtttt gttgatgcgc cccacttcaa tgattgcctg
     8821 agtcagtccg gagggacgtt cacttttcag caatgaacgg accagcactg aggcctgtac
     8881 tttgcccagc ttcagggagc ctgcggtccg gatcatttcg tcccactgaa ggactatttt
     8941 tcggggatct gattgccctc tggcaatatc attcagcacg ccatagtcgg catcatggtc
     9001 cattcgccag aaaaccgaag caccggcatc agccaggcgt ggagaaaact ggtatcccag
     9061 cagccagaaa aggccaaaga caagatcgct ggcacctgcc gtatcggtca taatttcggt
     9121 tggattcagc ccggtctcct gttccagaag gccttccagc acaaagatag agtccctcag
     9181 cgtccccggt ataacgatgc catgaaagcc ggaatactga tcggacacaa agttgtacca
     9241 ggtgatccct ctgttattac caaagtattt gcggttcggt ccggcattga ttgttctgac
     9301 tggcgtaaca aagcgcattc catctgcaga tgccacttct cctccacccc atatctgtgc
     9361 cagtggcagc gttgcctgaa aatcaaccag tctggcatta gcgctggtga tagtttcagc
     9421 ccgcagatag ttcgcttttg tccagttcag ccggtgtcgg gtcagtgcag gaacatttga
     9481 tctgatcagt ggttccagac cgatattgca ggcttcagcc atcagcacgg cgctgatgct
     9541 gacgggcaga tcatcaactc tggcactggc ttcactggca tggaaaaact catcagcaaa
     9601 tccggtatgg gcgttaattt cgagcagcaa ctccgttaaa tccaccggag ggagcagatc
     9661 actgatcatt ttgctcagtc gtttcagact gtccggctca tcaagactgg cgaggggaga
     9721 aattgtcaac cggggcttcg ggccagaaac atcgagttcg acagcctcat tttcgccaag
     9781 acgtgcagca acctgtctgt aacgactatc aagctgatgg cccagagatt ttattgcttc
     9841 ctgcgggtct gtcgggtgcc ccaaagaacg ataaacctta atccgatttg cctgccagtc
     9901 agcaccctgt agtaatcttg cacgaggatc tccccaccgg ttactgccgg taacgtagac
     9961 atccctccgt ctcagactat cctgcagttt actgagaaag cagagcgtgt atccccttcg
    10021 ggtgatatgt ttttccttgt taatcaccag ccgtttccat gactgactga tgatttccgt
    10081 tggtgcgtcg tcaaaaaact gccgccgtga gctgaactcc cggctgaggt agtcacaggc
    10141 attcagagtg gtaaccccgg caggtgcgga tgaaaattta acggtattca gcagatgggg
    10201 caggaaacga cgaacgcgcc cgtactgctc caccatttcg tcatgaaaat tatcgtctga
    10261 gggccgggca atttcacgga caagcgtgat gatttcagcc agcttttgcc tagggatgta
    10321 gctgaacacc tcagcacgaa tcgattcgtc cggtgtttct tctttcagca agtacgaaca
    10381 tgcgctggcg agcgccaatg cagatttatc cagatccttc agcgagcgga gccgtttttt
    10441 ctgcccaatc tttctggcgt cacggatgat aacggccagc atggcgtcca gaacgtccag
    10501 tgcatcatcc agcgccagcg tttcccatgc aaggacaaag gcaaccagaa ccgccatcct
    10561 tttctgcggt gacatcctgg caatattgaa caccgaagtc ataccagcat aacgtgcgag
    10621 atttttcagg cgcacagccg ggagtgtact caggttttca gcatgcaggc caaaatcgtt
    10681 cagagttttc cagcgttcaa ttgcttcatt aaacgccgga ccactgatgg tcacagggcc
    10741 ttttttcagt gattccagta aagacaggcg gctgcaatca gttggcccca gcagcatctc
    10801 cagctgtgaa cgctgttcgg ctgacggtat cagtgccagt ttgttccaca ggcgcaacgt
    10861 cgccttttcc cttacctctg aaatcaaccg ggtcagcgtg gtggctccgg ggagaataat
    10921 acgatgttgc ataagccacc ctgtcgccag gtcgaaaagc aggccaggac gttcgttgct
    10981 tatccagctc cgggtatata aaagacgggt aaggcgaaat gtccagggcc aggcaaattc
    11041 acgatactga tagtgctgac gtatcagcgc tgcatgctca cggcgggtat tttccctctg
    11101 accgtattct gcaagaacgg tgatatcacg aatcccgagc tgtctggcgg taaaatgccg
    11161 gacgccggaa ggaatatgat tcatgtcagt aagaaaagtg cccagaaaac gcacacaccc
    11221 gatttgcagg gcaataccaa gtcgattgtg atcaccccgg cttttcccga taaattcttt
    11281 atccgcttca tcaagatgaa aataacgcgc cagctgaagt tcatcgggtt cgccagtgaa
    11341 cctgccataa ctctcaacct gctcagtggt caaaaaatca acgggcatat cggcctccct
    11401 gcctgacggc ttttttaaca caactgcaac cgttcgaaat attataaatt atcagacata
    11461 gtaaaacggc ttcgtttgag tgtccattaa atcgtcattt tggcataata gacacatcgt
    11521 gtctgatatt cgatttaagg tacattttta tgcgaatttt tggttatgcg cgggtctcaa
    11581 ccagccagca gtccctcgat attcagatca gagcgctcaa agatgcaggg gtaaaagcta
    11641 accgcatctt taccgacaag gcatccggca gttcaacaga tcgggaaggg ctggatttgc
    11701 tgaggatgaa ggtggaggaa ggtgatgtca ttctggtgaa gaagctcgac cgtcttggcc
    11761 gcgacaccgc cgacatgatc caactgataa aagagtttga tgctcagggt gtagcggttc
    11821 ggtttattga cgacgggatc agtaccgacg gtgatatggg gcaaatggtg gtcaccatcc
    11881 tgtcggctgt ggcacaggct gaacgccgga ggatcctaga gcgcacgaat gagggccgac
    11941 aggaagcaaa gctgaaagga atcaaatttg gccgcaggcg taccgtggac aggaacgtcg
    12001 tgctgacgct tcatcagaag ggcactggtg caacggaaat tgctcatcag ctcagtattg
    12061 cccgctccac ggtttataaa attcttgaag acgaaagggc ctcgtgatac gcctattttt
    12121 ataggttaat gtcatgataa taatggtttc ttagacgtca ggtggcactt ttcggggaaa
    12181 agtgcgcgga acccctattt gtttattttt ctaaatacat tcaaatatgt atccgctcat
    12241 gagacaataa ccctgataaa tgcttcaata atattgaaaa aggaagagta tgagtattca
    12301 acatttccaa acaaagttag gcatcacaaa gtacagcatc gtgaccaaca gcaacgattc
    12361 cgtcacactg cgcctcatga ctgagcatga ccttgcgatg ctctatgagt ggctaaatcg
    12421 atctcatatc gtcgagtggt ggggcggaga agaagcacgc ccgacacttg ctgacgtaca
    12481 ggaacagtac ttgccaagcg ttttagcgca agagtccgtc actccataca ttgcaatgct
    12541 gaatggagag ccgattgggt atgcccagtc gtacgttgct cttggaagcg gggacggatg
    12601 gtgggaagaa gaaaccgatc caggagtacg cggaatagac cagttactgg cgaatgcatc
    12661 acaactgggc aaaggcttgg gaaccaagct ggttcgagct ctggttgagt tgctgttcaa
    12721 tgatcccgag gtcaccaaga tccaaacgga cccgtcgccg agcaacttgc gagcgatccg
    12781 atgctacgag aaagcggggt ttgagaggca aggtaccgta accaccccag atggtccagc
    12841 cgtgtacatg gttcaaacac gccaggcatt cgagcgaaca cgcagtgttg cctaaccctt
    12901 ccatcgaggg ggacgtccaa gggctggcgc ccttggccgc ccctcatgtc aaacgttaaa
    12961 catcatgagg gaagcggtga tcgccgaagt atcgactcaa ctatcagagg tagttggcgt
    13021 catcgagcgc catctcgaac cgacgttgct ggccgtacat ttgtacggct ccgcagtgga
    13081 tggcggcctg aagccacaca gtgatattga tttgctggtt acggtgaccg taaggcttga
    13141 tgaaacaacg cggcgagctt tgatcaacga ccttttggaa acggcactgt tgcaaatagt
    13201 cggtggtgat aaacttatca tccccttttg ctgatggagc tgcacatgaa cccattcaaa
    13261 ggccggcatt ttcagcgtga catcattcgg tgggccgtac gctggtactg caaatacggc
    13321 atcagttacc gtgagctgca ggagatgctg gctgaacgcg gagtgaatgt cgatcactcc
    13381 acgatttacc gctgggttca gcgttatgcg cctgaaatgg aaaaacggct gcgctggtac
    13441 tggcgtaacc cttccgatct ttgcccgtgg cacatggatg aaacctacgt gaaggtcaat
    13501 ggccgctggg cgtatctgta ccgggccgtc gacagccggg gccgcactgt cgatttttat
    13561 ctctcctccc gtcgtaacag caaagctgca taccggtttc tgggtaaaat cctcaacaac
    13621 gtgaagaagt ggcaga
//
