LOCUS       NZ_CP090625            23548 bp    DNA     circular CON 08-DEC-2023
DEFINITION  Klebsiella pneumoniae isolate KpBO_TO5 plasmid unnamed2, complete
            sequence.
ACCESSION   NZ_CP090625
VERSION     NZ_CP090625.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN24648678
            Assembly: GCF_021484985.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 23548)
  AUTHORS   Gaibani,P.
  TITLE     In vivo emergence of Imipenem/relebactam resistance in KPC-producing
            Klebsiella pneumoniae mediated by increased blaKPC copy number and
            porins
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 23548)
  AUTHORS   Gaibani,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JAN-2022) Microbiology, Policlinico
            Sant'Orsola-Malpighi, Via Massarenti 9, Bologna, BO 40138, Italy
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 20x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina iSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/08/2023 11:12:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,581
            CDSs (total)                      :: 5,459
            Genes (coding)                    :: 5,350
            CDSs (with protein)               :: 5,350
            Genes (RNA)                       :: 122
            rRNAs                             :: 9, 7, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 7, 8 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 52 of 109
            Pseudo Genes (incomplete)         :: 57 of 109
            Pseudo Genes (internal stop)      :: 14 of 109
            Pseudo Genes (multiple problems)  :: 13 of 109
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP090625.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..23548
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /isolate="KpBO_TO5"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="unnamed2"
                     /geo_loc_name="Italy"
                     /lat_lon="45.0703 N 7.6869 E"
                     /collection_date="2021-09-04"
                     /collected_by="Turin"
                     /genotype="ST512"
     gene            join(22527..23548,1..4)
                     /gene="istA"
                     /locus_tag="L0103_RS27670"
                     /old_locus_tag="L0103_27670"
     CDS             join(22527..23548,1..4)
                     /gene="istA"
                     /locus_tag="L0103_RS27670"
                     /old_locus_tag="L0103_27670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032490293.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="WP_004199214.1"
                     /translation="MLTQEQTVEIRVLARQGHSIRHIARTLGVSRNTVRRYLRDPSVAR
                     YQPREPRPTKLGPFESYLRQRVEQAHPIWLPATVLNREIRAQGYGGGLSLLRAFLATLK
                     PARREAGPAVRFETEPGRQLQADFVVLRRARSPMSAFVATLGYSRMTFVTFVPDESFES
                     VRDSLLLAFDYLGGVPREVLFDNMKTVVLERDAYGDGKHRFHPGLLQLADDLGFRIRLC
                     RPYRAQTKGKVERFNRYFRESFYNPLLTRMKGTGLLLDCAAANRRVRDWLADEANVRVH
                     ATLNERPIDRWRQEREHLQPLPSRVRRDEAPLLDNSLRPVPLESLQHPLSVYDAIGEAC
                     R"
                     /name="istA"
     gene            1..780
                     /gene="istB"
                     /locus_tag="L0103_RS27675"
                     /old_locus_tag="L0103_27675"
     CDS             1..780
                     /gene="istB"
                     /locus_tag="L0103_RS27675"
                     /old_locus_tag="L0103_27675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element ISKpn7 family helper ATPase
                     IstB"
                     /protein_id="WP_004152394.1"
                     /translation="MNLQHERIDALCQQLKLERVATHYPVLAQQAVREDFSFTDFLEHL
                     LRHEAGCRQQRSRELLTRMACFPGIKTLEDYDFSFNPGVPKALVQELGSLAFVERAENV
                     VLIGPSGIGKTHLAIALGYKAAQAGVKTRFITAADLMLQLSTAQRQGRLKEYFNRAILG
                     PRLLVIDEIGYLPFGREEANLFFQVVAKRYEKGAMILTSNLPFSQWADAFAGDTTLTAA
                     MLDRLLHHAHILTLSGESYRLKDKRKAGVVRKNSKPE"
                     /name="istB"
     gene            777..1016
                     /locus_tag="L0103_RS27930"
     CDS             777..1016
                     /locus_tag="L0103_RS27930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004152395.1"
                     /translation="MIQVGQYYFGDSGVKWVSFQLVLTPAYPRCYLRAPIVGAWPGLPE
                     AVRNVDAEVRRGGRPMNADLIRFSSSVIIPAVAA"
                     /name="hypothetical protein"
     gene            1068..1949
                     /locus_tag="L0103_RS27680"
                     /old_locus_tag="L0103_27680"
     CDS             1068..1949
                     /locus_tag="L0103_RS27680"
                     /old_locus_tag="L0103_27680"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015256839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbapenem-hydrolyzing class A beta-lactamase
                     KPC-3"
                     /protein_id="WP_004152396.1"
                     /translation="MSLYRRLVLLSCLSWPLAGFSATALTNLVAEPFAKLEQDFGGSIG
                     VYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLARSQQQAGLLDTPIRYGKNALVPW
                     SPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFRLDR
                     WELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQQFVDWLKGNTTGNHRIRA
                     AVPADWAVGDKTGTCGVYGTANDYAVVWPTGRAPIVLAVYTRAPNKDDKYSEAVIAAAA
                     RLALEGLGVNGQ"
                     /name="carbapenem-hydrolyzing class A beta-lactamase KPC-3"
     gene            complement(2199..3518)
                     /locus_tag="L0103_RS27685"
                     /old_locus_tag="L0103_27685"
     CDS             complement(2199..3518)
                     /locus_tag="L0103_RS27685"
                     /old_locus_tag="L0103_27685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152397.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISKpn6 family transposase"
                     /protein_id="WP_004152397.1"
                     /translation="MAASYLPYRPDQSYLLPPSLGEWLPEGHLAYFISETVDTLDLSAF
                     HARYAGGGPGNQPFHPAMMVKVLIYGYASGVFSSRKLARKLYEDVALRVLAAGNFPAHR
                     TLSDFRALHLTELENLFVQVVQLARECGLVKLGTIAVDGTKVKANASRHKAMSYKRMKP
                     AEDELHCEIKALLDRAKATDDQERNEPELDIPAEISRREKRLEAIQAAKARLEARQREA
                     DQARGRSEDDGRRPRHPDGSDKGGGSYKREFGVPDDRDQESFTDPDSRIMKHAGGGSEQ
                     SYNGYTAVDAEHQIIVAAELTNCAADSQALLGMLAAVQANTGEMPAQTLADAGFRSEAV
                     LAKVADHHGDVIVALGREGREDAKVNAKTHPHTAAIAAKLKTEQGDAAYRRRKSIVEAP
                     NGWIKAVMGLRQFSMRGLDKVQAEWKLVCMALNLRRMAYL"
                     /name="IS1182-like element ISKpn6 family transposase"
     gene            3837..4589
                     /locus_tag="L0103_RS27690"
                     /old_locus_tag="L0103_27690"
     CDS             3837..4589
                     /locus_tag="L0103_RS27690"
                     /old_locus_tag="L0103_27690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-relaxation family protein"
                     /protein_id="WP_234859577.1"
                     /translation="MAEFSGVPAYPPYNVSHAKRQARNAEKTRLTLRWLREELCSTAEL
                     VARRLGIAAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLA
                     DVIPFQPSRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGK
                     TVAFEVERTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIV
                     NPQTGEARKTAELDRERLFACFKFMTTE"
                     /name="replication-relaxation family protein"
     gene            4596..5126
                     /locus_tag="L0103_RS27695"
                     /old_locus_tag="L0103_27695"
     CDS             4596..5126
                     /locus_tag="L0103_RS27695"
                     /old_locus_tag="L0103_27695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(5154..5333)
                     /locus_tag="L0103_RS27700"
                     /old_locus_tag="L0103_27700"
     CDS             complement(5154..5333)
                     /locus_tag="L0103_RS27700"
                     /old_locus_tag="L0103_27700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            5402..5779
                     /locus_tag="L0103_RS27705"
                     /old_locus_tag="L0103_27705"
     CDS             5402..5779
                     /locus_tag="L0103_RS27705"
                     /old_locus_tag="L0103_27705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            complement(5841..6140)
                     /locus_tag="L0103_RS27710"
                     /old_locus_tag="L0103_27710"
     CDS             complement(5841..6140)
                     /locus_tag="L0103_RS27710"
                     /old_locus_tag="L0103_27710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(6130..6393)
                     /locus_tag="L0103_RS27715"
                     /old_locus_tag="L0103_27715"
     CDS             complement(6130..6393)
                     /locus_tag="L0103_RS27715"
                     /old_locus_tag="L0103_27715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            complement(6699..>6989)
                     /locus_tag="L0103_RS27720"
                     /old_locus_tag="L0103_27720"
                     /pseudo=""
     CDS             complement(6699..>6989)
                     /locus_tag="L0103_RS27720"
                     /old_locus_tag="L0103_27720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /name="Exc2 family lipoprotein"
     gene            complement(7024..10029)
                     /locus_tag="L0103_RS27725"
                     /old_locus_tag="L0103_27725"
     CDS             complement(7024..10029)
                     /locus_tag="L0103_RS27725"
                     /old_locus_tag="L0103_27725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /protein_id="WP_001143775.1"
                     /translation="MPVDFLTTEQVESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHDEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISQSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLGENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASDLVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQASVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGALGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
                     /name="Tn3-like element Tn3 family transposase"
     gene            10191..10748
                     /locus_tag="L0103_RS27730"
                     /old_locus_tag="L0103_27730"
     CDS             10191..10748
                     /locus_tag="L0103_RS27730"
                     /old_locus_tag="L0103_27730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001217881.1"
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="recombinase family protein"
     gene            10982..11536
                     /gene="aac(6')-Ib"
                     /locus_tag="L0103_RS27735"
                     /old_locus_tag="L0103_27735"
     ARG             10983..11533
                     /name="aac(6')-Ib"
                     /gene="aac(6')-Ib"
                     /gene_name="AAC(6')-Ib family aminoglycoside
                     6'-N-acetyltransferase"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            11606..>11821
                     /locus_tag="L0103_RS27740"
                     /old_locus_tag="L0103_27740"
                     /pseudo=""
     CDS             11606..>11821
                     /locus_tag="L0103_RS27740"
                     /old_locus_tag="L0103_27740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001424636.1"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /name="nucleotidyltransferase domain-containing protein"
     gene            11887..12591
                     /locus_tag="L0103_RS27745"
                     /old_locus_tag="L0103_27745"
     CDS             11887..12591
                     /locus_tag="L0103_RS27745"
                     /old_locus_tag="L0103_27745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_004217321.1"
                     /translation="MNPFKGRHFQRDIIRWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            <12646..12816
                     /locus_tag="L0103_RS27750"
                     /old_locus_tag="L0103_27750"
                     /pseudo=""
     CDS             <12646..12816
                     /locus_tag="L0103_RS27750"
                     /old_locus_tag="L0103_27750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /name="serine hydrolase"
     gene            <12964..13548
                     /locus_tag="L0103_RS27755"
                     /old_locus_tag="L0103_27755"
                     /pseudo=""
     CDS             <12964..13548
                     /locus_tag="L0103_RS27755"
                     /old_locus_tag="L0103_27755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]; GO:0043022 - ribosome binding
                     [Evidence IEA]; GO:0003723 - RNA binding [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3/pyocin S6 family cytotoxin"
                     /name="colicin E3/pyocin S6 family cytotoxin"
     gene            13558..13815
                     /locus_tag="L0103_RS27760"
                     /old_locus_tag="L0103_27760"
     CDS             13558..13815
                     /locus_tag="L0103_RS27760"
                     /old_locus_tag="L0103_27760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            13900..14049
                     /locus_tag="L0103_RS27765"
                     /old_locus_tag="L0103_27765"
     CDS             13900..14049
                     /locus_tag="L0103_RS27765"
                     /old_locus_tag="L0103_27765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            15530..17494
                     /locus_tag="L0103_RS27770"
                     /old_locus_tag="L0103_27770"
     CDS             15530..17494
                     /locus_tag="L0103_RS27770"
                     /old_locus_tag="L0103_27770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            complement(17566..19281)
                     /gene="tnpR"
                     /locus_tag="L0103_RS27775"
                     /old_locus_tag="L0103_27775"
     CDS             complement(17566..19281)
                     /gene="tnpR"
                     /locus_tag="L0103_RS27775"
                     /old_locus_tag="L0103_27775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn4401 family resolvase TnpR"
                     /protein_id="WP_004152391.1"
                     /translation="MKTGQTTASSSTPVGFPDADSLAALRGWYAGLSSRAAVEHYLAAR
                     KAAGQSARGMLGHIRRQLIVFANSRHRPDLADVFQHAPEERQGRAGAVERAIRLLPTLP
                     APKPQISDSIDQWLSPRTVRALQAYGIHTLSALTVRIPRRRGWWKAIEGLGMTGARQVE
                     AFFAAHPQLTERARALIPIIQPSGIVPWEQLRLPNEVDGSQGNFRAPRNACTLNATNDY
                     EAVQAWLALHETVATQRAYRKEAARLILWAIVERGRALSSLTTDDAIAYRAFVRHPTPR
                     ERWVGPPRPRDSVEWRPFSGGLSARSAAYALTVLSALFRWLIEQRYVLANPFAGVKVRG
                     HALRPALDTARGFTEGEWLLLRAIADGLEWSYGWSEPAAQRLRFMLDFGYATGLRASEL
                     VGAVLGNVRLDEHGDHWLHLVGKGGKPGKVALPPLAYTALDQYLAQRQLPVSRERWNPK
                     TPLVGSLGEDGNAGITGPHLWCVLRRFFTQAAEAIEADHPVAAEKLRRATPHWMRHSHA
                     SHALARGAQLTAVRDNLRHASIATTSMYLHGDELERARQMRQAFGARHVKRGVD"
                     /name="tnpR"
     gene            19391..22420
                     /gene="tnpA"
                     /locus_tag="L0103_RS27780"
                     /old_locus_tag="L0103_27780"
     CDS             19391..22420
                     /gene="tnpA"
                     /locus_tag="L0103_RS27780"
                     /old_locus_tag="L0103_27780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152392.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn4401 family transposase"
                     /protein_id="WP_004152392.1"
                     /translation="MSKKNKLLSVLSDAEQEALYGLPEFDDAQQLEYLAVTETELALAN
                     SRPSLHAKVYCLLQIGYFKAKHAFFSFDWDEVEDDCAFVLSRYFHGEVFEPKAITKHER
                     YTQREQIAKLFGYWPWSAAFLPQLEQQAARTVRRDVTPGFVAAELIVWLNEHKIIRPGY
                     TTLQELVSETLSAERRRLGNLLEQALDESAKAALSQLLVRDDTLSQLAALKQDAKNFGW
                     RQMVREREKRATLEPLHAIAKTLLPKLDVSQQNLLYYASLANFYTVHDLRNLKADQTQL
                     YLLCYAWVRYRQLSDNLVDAMAYHMKQLEDESSAGAKQSFADEQVRRQQETPRVGRLLS
                     LYVDDSVADPTPFGEVRQRAYKIMPRDTLQTTAQRMSVKPASKLALQWQAVDGLADRMR
                     RHLRPLYVALDLSGSNPDSPWLAALAWAKGVFAKQQRLSQRPLDEWPAATLPKRLRPYL
                     LTFDADGKPTGLHADRYEFWLYRQIRKRLQSGELYLDDSLQHRHFSDELVEMDRKIDVL
                     AKMEIPFLQQPVHAQLDALTAELRTQWLAFNRELKQGKLTHLEYNKDTQKLTWRKPKSE
                     NEKAREKAFYEKLPFCDVADVFRFVNDECKFLSAFTPMQPRYAKKVADADSLMAVIIAQ
                     AMNHGNHVMARTSDIPYHVLDSGYQQYLRQATLHAANDCISNAIATLPIFPYYSFDLET
                     LYGAVDGQKFSVERPTVKARYSRKYFGRGKGVVAYTLLCNHIPLNGYLIGAHDYEAHHV
                     FDIWYRNTSDIMPTAITGDMHSVNKANFAILHWFGRRFEPRFTDLNAQLKELYCADDPA
                     QYQACLIRPVGKIDCDLIHREKPNIDRIVATLGLKEMTQGTLIRKLCTYTTTNPTRRAI
                     FEFDKLIRSIYTLRYLRDPQLERNVHRSQNRLESYHQLRSAIAQVGGKKELTGRTDIEI
                     EISNQCARLIANTIIFYNSAILSRLVTKYEAAGNSKALALITKISPAAWRHILLNGHYT
                     FQSSGKTIDLDAIVAGLELE"
                     /name="tnpA"
     ARG             1069..1946
                     /name="blaKPC-3"
                     /gene="blaKPC-3"
                     /gene_name="carbapenem-hydrolyzing class A beta-lactamase
                     KPC-3"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             11619..11875
                     /name="aadA15"
                     /gene="aadA15"
                     /gene_name="ANT(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="97.14"
                     /coverage="32.32"
     ARG             10932..11536
                     /name="AAC(6')-Ib10"
                     /gene="AAC(6')-Ib10"
                     /gene_name="AAC(6')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="98.97"
                     /coverage="99.01"
     Typing          complement(14153..14731)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          3874..4586
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="98.0"
                     /evalue="1.67e-146"
ORIGIN
        1 atgaacctcc agcatgagcg gatcgacgcc ctgtgccagc aactcaaact cgaacgggtg
       61 gcaacgcatt accccgtcct ggcgcagcag gcggtgcgcg aggacttcag cttcaccgac
      121 ttcctggaac acctgttgcg gcatgaagcg gggtgtcgcc agcagcgcag ccgcgaactg
      181 ctgacgcgga tggcttgctt cccgggcatc aagaccctgg aggactatga cttcagcttc
      241 aaccccggcg tgcccaaggc actggtgcag gagctgggca gtctggcgtt tgtcgaacgg
      301 gccgagaacg tggtgctgat cggaccctct ggcatcggca agacccacct cgccatcgcc
      361 ttgggttaca aggccgcgca agccggggtc aagacacgct tcatcacggc agccgacctg
      421 atgctgcaac tgagcacggc gcagcgacaa gggcggctga aggaatactt caaccgcgcc
      481 atcctcggtc cacggctgct ggtgatcgat gagatcggct acctgccttt cggacgcgag
      541 gaagcgaacc tgttctttca ggtggtggcg aagcgctatg agaaaggggc gatgatcctg
      601 acctcgaacc tgccgttcag ccagtgggcc gacgcgtttg ccggcgatac caccctgaca
      661 gccgcgatgc tggatcggct gctgcaccat gcccatatcc tgaccctgag cggcgaaagc
      721 taccgcttga aggacaagag gaaggcggga gtggtcagga aaaattccaa acccgaatga
      781 tccaggtggg tcagtattac tttggtgatt caggggtaaa gtgggtcagt tttcagttgg
      841 tgttgacacc ggcgtaccct cggtgctatc ttcgcgcccc aatagtcggg gcttggccag
      901 gacttcctga ggccgtccgt aacgtggatg ccgaggtcag gcgaggtggc cgacccatga
      961 acgccgacct gattcgtttt tcaagctcgg tgataatccc agctgtagcg gcctgattac
     1021 atccggccgc tacacctagc tccaccttca aacaaggaat atcgttgatg tcactgtatc
     1081 gccgtctagt tctgctgtct tgtctctcat ggccgctggc tggcttttct gccaccgcgc
     1141 tgaccaacct cgtcgcggaa ccattcgcta aactcgaaca ggactttggc ggctccatcg
     1201 gtgtgtacgc gatggatacc ggctcaggcg caactgtaag ttaccgcgct gaggagcgct
     1261 tcccactgtg cagctcattc aagggctttc ttgctgccgc tgtgctggct cgcagccagc
     1321 agcaggccgg cttgctggac acacccatcc gttacggcaa aaatgcgctg gttccgtggt
     1381 cacccatctc ggaaaaatat ctgacaacag gcatgacggt ggcggagctg tccgcggccg
     1441 ccgtgcaata cagtgataac gccgccgcca atttgttgct gaaggagttg ggcggcccgg
     1501 ccgggctgac ggccttcatg cgctctatcg gcgataccac gttccgtctg gaccgctggg
     1561 agctggagct gaactccgcc atcccaggcg atgcgcgcga tacctcatcg ccgcgcgccg
     1621 tgacggaaag cttacaaaaa ctgacactgg gctctgcact ggctgcgccg cagcggcagc
     1681 agtttgttga ttggctaaag ggaaacacga ccggcaacca ccgcatccgc gcggcggtgc
     1741 cggcagactg ggcagtcgga gacaaaaccg gaacctgcgg agtgtatggc acggcaaatg
     1801 actatgccgt cgtctggccc actgggcgcg cacctattgt gttggccgtc tacacccggg
     1861 cgcctaacaa ggatgacaag tacagcgagg ccgtcatcgc cgctgcggct agactcgcgc
     1921 tcgagggatt gggcgtcaac gggcagtaag gctctgaaaa tcatctattg gcccaccacc
     1981 gccgcccttg cgggcggcat ggattaccaa ccactgtcac atttaggcta ggagtctgcg
     2041 cggcagagcc gtgtgaccgg ttttctgtag agcactgacg atggcggcgg cgctctctgc
     2101 aattggcaag gcgtcggcgc caaggatacc aatcttgcgg cgcgcggcgt gttatgacga
     2161 ctggggtgca tttgagccgc cccatttaac cttcgccctc acagatacgc cattcgcctc
     2221 agatttagcg ccatgcagac gagcttccac tcggcttgca ccttgtccag gcccctcatg
     2281 ctgaactgac gcaatcccat caccgccttg atccaaccat tcggagcctc cacgatcgac
     2341 ttgcgccggc ggtaagctgc atcgccttgc tccgttttca atttcgccgc aatcgccgcc
     2401 gtatgcggat gggtcttggc attgaccttg gcatcttcac gtccctcgcg gccgagggca
     2461 acgatgacat cgccgtggtg atcggcgacc tttgccagaa cagcctcact acggaatccc
     2521 gcatccgcca gcgtctgggc cggcatttct ccggtgttgg cctgaactgc tgccagcatg
     2581 cccagcagcg cctgactgtc cgcggcgcag ttggtcaact ccgccgccac gatgatctgg
     2641 tgctcggcat cgaccgctgt gtacccgttg tagctctgct cggagccacc accggcgtgt
     2701 ttcatgatcc ggctgtccgg atcggtgaag ctttcctgat cacggtcatc cggcacacca
     2761 aactcgcgtt tgtacgagcc accgcccttg tccgagccat ccggatggcg aggccggcgg
     2821 ccatcgtctt cgctgcgccc ccgggcctgg tccgcttcac gctggcgcgc ttccaggcgc
     2881 gcctttgccg cctggatcgc ctccaggcgc ttctcgcggc gagaaatctc ggcaggaatg
     2941 tccagctccg gctcgttacg ctcctggtcg tcggtagcct tggcgcgatc aagcagcgcc
     3001 ttgatctcgc aatgcaattc gtcctcggcc ggcttcatgc gcttatagct catcgccttg
     3061 tggcggctgg cgttggcttt taccttggtg ccgtcgaccg cgatcgtgcc aagcttcacc
     3121 agcccacatt cgcgcgccag ttgcaccacc tgaacgaaca aattctcaag ctcggtcagg
     3181 tgtagggcac ggaagtcact cagcgtgcgg tgggccggga agtttccagc ggccagcaca
     3241 cgcaacgcga catcctcgta cagcttcctg gctagtttgc gcgaagagaa gacgccgctc
     3301 gcgtaaccat agatcagcac tttgaccatc atcgccggat gaaacggctg attgcccgga
     3361 ccaccgccgg cataccgggc gtggaatgcg ctcaagtcca gcgtatcgac agtctcgctg
     3421 atgaagtagg caagatgccc ttcaggtagc cactctccca gagaaggggg cagcagatag
     3481 gattggtcgg gtcggtaagg aaggtaactg gcagccatcc ccgtatcgtc ctcgatcttc
     3541 cgccgatttg gcttctgccg cgcaggctcc taggccaccg tagctaaaca tacgagaaaa
     3601 accgcttctt gagcgctctc tgagaccacc ttgccgacaa cgcagaaacg gttgcggaaa
     3661 aatcggcgtt tccggcgtac gccacccgac ctggacgaac tattgcggac ctggaactgg
     3721 agtagcggaa ttccccgggg tttcagcgtc gcgccacagc gcctcagata gatgcggtag
     3781 cctttggcgg gtcgtcatgc cgcggaccac ccccccaaaa aattccacaa tgcggaatgg
     3841 cggaattttc tggggttccc gcttaccccc cctacaacgt cagccacgcg aaacgacagg
     3901 cgcggaacgc ggagaaaacc cggctgaccc tgcgctggtt gcgggaagag ctgtgttcca
     3961 cggcggagct ggttgcgcgg cggctgggga ttgcggcggt gcagccggtc taccgcttcc
     4021 tcgacagcct ggtggcgaaa gggctgctgg tccggaccaa atatccggtg gacggccgtc
     4081 aggtcagcgt gtgggggctg acgccgcatg gcgtggcgtt ctcgttcgac gaggacgaac
     4141 cgctggcgga tgttattccg tttcagccgt caagggtgtc ggcagcacat ctgccgcacc
     4201 ggctggccgt gcaatccctg cgccttgata tggaagccag aggggccacc ggctggcgca
     4261 ttctgcaccg tctgagtctt aaaggcatga aagtgccgga cgccctggcg gagctggacg
     4321 gtaaaacggt ggcgtttgag gtggagcgca ccgtcaagag ccgtcgccgg tatcaggaag
     4381 tggtgtccgg gtatctgttc aaccgcaaag ctaacggcat cgatgaaatc tggtacatct
     4441 gcccggaccg ggcgacgcag gtcagggtgc agcgggcaat cctgtcggtg gatgaaatcg
     4501 tgaacccaca gaccggcgag gcccgcaaaa cggcagagct ggatcgtgaa cggttgtttg
     4561 cgtgctttaa atttatgaca acggagtgag ggattatggc gctgtacatg gtatttattg
     4621 aagacgcgga ggaccggaac ggcgagcgct gcatcatgcc gaccagcgag catctggaag
     4681 atatggtggt gctcgcctgg cagaccgggg cgtatgtttt ctgttttgtc gaccgggccc
     4741 agcatctggc gatgatgaaa tccatcggga tgtatgacga gcggctcaac agcgacgaaa
     4801 aagccacgta ctttttcact ggtaaaaatc cgcaatggga acggaacaaa cccacaggaa
     4861 tgaagctgtg tgattacctc tatcgcaagg tggagcggtt cgccatcgag aacggtgtgc
     4921 aggtggttga tgccgggaag tgctcaccgg agcagattaa cgcgatgatt gacgtggtga
     4981 gtgagcggca cggggaaagc gcggtgaacg agaagctgaa agcggagctg atgcgggaat
     5041 ataacagccg ctattttaac gtgccggtac ctgaactgcc ggaggacaaa cctgcccgcc
     5101 ggtggtggcc gttcggcaaa aaataaatgc cagcaccggc catgccggtg ctgttattcc
     5161 tccccgagct tatcccgcat cacctgccag agtgtttccg catcctcgtg tagccgctcg
     5221 cacatgtcgg ccggggtatc catatccagc tcattcagtt tatcgagcaa tagcagcgac
     5281 tgctccttaa taaatttagc catattgagg gctgtttttt cctgttttgt catgattctt
     5341 tccttccggg catggtgtgc gcctgtcagg tatactgtct caaaaatagc ggggtgagac
     5401 aatggcgtgg gtgacggtga gacaggcgac ggaactgacg ggtaaagccc gaagttccct
     5461 gtatcgggat atggcgaaag gccgcgtatc ataccgtacg gaagctgatg gcggccgggt
     5521 ggtggatacc agcgagctta tccgggtgta cggtgagtta agacaggatg agactcacga
     5581 gcgggacgag ttgagactgt cgggtgagac tgaaaaaatg gcctccgacg cgttgatcgc
     5641 ggagataaaa gcactcaggg aggaggtggc cgggctacgg caggaaatgc agtccatgag
     5701 actgctggaa cacaaaccgg agacagcaga gaccccggcc ggaacaccgc gccggtggtg
     5761 gccgtgggga aaacgctgac gcgctgtgct tgtccaaccg gcgacggcca cgcaatgaat
     5821 tgcgtccccg tcaccggtta ttagagaaca atatggggat tctggcgctg gccgaccacg
     5881 gccagaaccc ggacttttct ggtctggtca tcaacatcat agaggacatg ctgtcccatc
     5941 agactgatcc ggcgaacgtc ctcgccatag cgtgagtcca cttcatagag tcgcgggaag
     6001 tcggccagtt tgtccgccgc agcgagaacc cggtcggtaa cgttctgcgc atcccacagg
     6061 gatgaatttt ccgcgatata gtcaaacagc gtcgttacat cctcgatggc tccctgcttc
     6121 cattccacgt catacggcat cgcgcagttc ctgataacgg ccatgcaggc gctggcggag
     6181 ttgttccgtg gtcatacccg gacgcgtgtc agcacgggcg gcggtcactt tggcgcgaac
     6241 ctgatcttca tactctgcct gggccagttc ttcgttagcc agtcgctgca acagcgcagc
     6301 tttgtccggg ccaccttccg gcagtatgcg gggcaggctt tcagccagtt cccgaagaaa
     6361 gttggcgttt tcgtagtgtg tagtgttgct cattgcggag cctcccgggt taatgcggca
     6421 atatgaagga agtttagcag ggggcggtct gaaagaatat ggtcgtgtca gtcaggctga
     6481 tgaagcagaa agtcggtaaa aaagggctta cggcatccat tttacgtcaa aacatatgcc
     6541 atgcagttgc gtgcataggc atgcattagg ataaaattta tcgggcgcgt ttccggcagt
     6601 tttccggggg ggttgttgcc tgttttatcc cgtagccgcc ggaaacgccc tgagcccgtc
     6661 tgagcggtgc gcgtaatgac gcgttatggt aaatccactt actgtctgcc ttcatagcca
     6721 tcgagataaa cagctgaaat ggtgtcagcc agtagccttg attttttcgg tgtgaggtct
     6781 ttgctgcggt aatcggtacc cgcaaattgt gttgtgcctt ggagtgagtt taaaaattcc
     6841 tgactgtgaa actgctgaat gcgttgctgc acatcactcc gtgattttcc ggtcgcttta
     6901 tcctttgcgc ccatatccca gaactgccgg aaaaaaggca ccatcattcg tgttgtgtca
     6961 gctttctggg tggaaaaatt gggatcaaaa ggggtctgac gctcagtgga acgaaaactc
     7021 acgttaagca acgttttctg cctctgacgc ctcttttaat ggtctcagat gacctttggt
     7081 caccagttct gccagcgtga aggaataatg gccgagcata ttgatatgtc cgtggcaaag
     7141 cggggagagg cgtgcgatat cttcatcatt cagtgtttca ccctgcgccc ggagatgatc
     7201 cagagctgcc tgcatataaa tagtgttcca taacacgacg gcgttagtga ccagccccag
     7261 agctcccaac tgatcttcct gaccgtcggt atatcgtttt cttatctcac ctttttgacc
     7321 gtgacagatg gctctggcaa ctgcatgacg gctttctccc cgattaagct gggtcagaat
     7381 gcgccggcgg taatcttcat catcaatata attaagcaga tacagcgttt tgttgatgcg
     7441 ccccacttca atgattgcct gagtcagtcc ggagggacgt tcacttttca gcaatgaacg
     7501 gaccagcact gaggcctgta ctttgcccag cttcagggag cctgcggtcc ggatcatttc
     7561 gtcccactga aggactattt ttcggggatc tgattgccct ctggcaatat cattcagcac
     7621 gccatagtcg gcatcatggt ccattcgcca gaaaaccgaa gcaccggcat cagccaggcg
     7681 tggagaaaac tggtatccca gcagccagaa aaggccaaag acaagatcgc tggcacctgc
     7741 cgtatcggtc ataatttcgg ttggattcag cccggtctcc tgttccagaa ggccttccag
     7801 cacaaagata gagtccctca gcgtccccgg tataacgatg ccatgaaagc cggaatactg
     7861 atcggacaca aagttgtacc aggtgatccc tctgttatta ccaaagtatt tgcggttcgg
     7921 tccggcattg attgttctga ctggcgtaac aaagcgcatt ccatctgcag atgccacttc
     7981 tcctccaccc catatctgtg ccagtggcag cgttgcctga aaatcaacca gtctggcatt
     8041 agcgctggtg atagtttcag cccgcagata gttcgctttt gtccagttca gccggtgtcg
     8101 ggtcagtgca ggaacatttg atctgatcag tggttccaga ccgatattgc aggcttcagc
     8161 catcagcacg gcgctgatgc tgacgggcag atcatcaact ctggcactgg cttcactggc
     8221 atggaaaaac tcatcagcaa atccggtatg ggcgttaatt tcgagcagca actccgttaa
     8281 atccaccgga gggagcagat cactgatcat tttgctcagt cgtttcagac tgtccggctc
     8341 atcaagactg gcgaggggag aaattgtcaa ccggggcttc gggccagaaa catcgagttc
     8401 gacagcctca ttttcgccaa gacgtgcagc aacctgtctg taacgactat caagctgatg
     8461 gcccagagat tttattgctt cctgcgggtc tgtcgggtgc cccaaagaac gataaacctt
     8521 aatccgattt gcctgccagt cagcaccctg tagtaatctt gcacgaggat ctccccaccg
     8581 gttactgccg gtaacgtaga catccctccg tctcagacta tcctgcagtt tactgagaaa
     8641 gcagagcgtg tatccccttc gggtgatatg tttttccttg ttaatcacca gccgtttcca
     8701 tgactgactg atgatttccg ttggtgcgtc gtcaaaaaac tgccgccgtg agctgaactc
     8761 ccggctgagg tagtcacagg cattcagagt ggtaaccccg gcaggtgcgg atgaaaattt
     8821 aacggtattc agcagatggg gcaggaaacg acgaacgcgc ccgtactgct ccaccatttc
     8881 gtcatgaaaa ttatcgtctg agggccgggc aatttcacgg acaagcgtga tgatttcagc
     8941 cagcttttgc ctagggatgt agctgaacac ctcagcacga atcgattcgt ccggtgtttc
     9001 ttctttcagc aagtacgaac atgcgctggc gagcgccaat gcagatttat ccagatcctt
     9061 cagcgagcgg agccgttttt tctgcccaat ctttctggcg tcacggatga taacggccag
     9121 catggcgtcc agaacgtcca gtgcatcatc cagcgccagc gtttcccatg caaggacaaa
     9181 ggcaaccaga accgccatcc ttttctgcgg tgacatcctg gcaatattga acaccgaagt
     9241 cataccagca taacgtgcga gatttttcag gcgcacagcc gggagtgtac tcaggttttc
     9301 agcatgcagg ccaaaatcgt tcagagtttt ccagcgttca attgcttcat taaacgccgg
     9361 accactgatg gtcacagggc cttttttcag tgattccagt aaagacaggc ggctgcaatc
     9421 agttggcccc agcagcatct ccagctgtga acgctgttcg gctgacggta tcagtgccag
     9481 tttgttccac aggcgcaacg tcgccttttc ccttacctct gaaatcaacc gggtcagcgt
     9541 ggtggctccg gggagaataa tacgatgttg cataagccac cctgtcgcca ggtcgaaaag
     9601 caggccagga cgttcgttgc ttatccagct ccgggtatat aaaagacggg taaggcgaaa
     9661 tgtccagggc caggcaaatt cacgatactg atagtgctga cgtatcagcg ctgcatgctc
     9721 acggcgggta ttttccctct gaccgtattc tgcaagaacg gtgatatcac gaatcccgag
     9781 ctgtctggcg gtaaaatgcc ggacgccgga aggaatatga ttcatgtcag taagaaaagt
     9841 gcccagaaaa cgcacacacc cgatttgcag ggcaatacca agtcgattgt gatcaccccg
     9901 gcttttcccg ataaattctt tatccgcttc atcaagatga aaataacgcg ccagctgaag
     9961 ttcatcgggt tcgccagtga acctgccata actctcaacc tgctcagtgg tcaaaaaatc
    10021 aacgggcata tcggcctccc tgcctgacgg cttttttaac acaactgcaa ccgttcgaaa
    10081 tattataaat tatcagacat agtaaaacgg cttcgtttga gtgtccatta aatcgtcatt
    10141 ttggcataat agacacatcg tgtctgatat tcgatttaag gtacattttt atgcgaattt
    10201 ttggttatgc gcgggtctca accagccagc agtccctcga tattcagatc agagcgctca
    10261 aagatgcagg ggtaaaagct aaccgcatct ttaccgacaa ggcatccggc agttcaacag
    10321 atcgggaagg gctggatttg ctgaggatga aggtggagga aggtgatgtc attctggtga
    10381 agaagctcga ccgtcttggc cgcgacaccg ccgacatgat ccaactgata aaagagtttg
    10441 atgctcaggg tgtagcggtt cggtttattg acgacgggat cagtaccgac ggtgatatgg
    10501 ggcaaatggt ggtcaccatc ctgtcggctg tggcacaggc tgaacgccgg aggatcctag
    10561 agcgcacgaa tgagggccga caggaagcaa agctgaaagg aatcaaattt ggccgcaggc
    10621 gtaccgtgga caggaacgtc gtgctgacgc ttcatcagaa gggcactggt gcaacggaaa
    10681 ttgctcatca gctcagtatt gcccgctcca cggtttataa aattcttgaa gacgaaaggg
    10741 cctcgtgata cgcctatttt tataggttaa tgtcatgata ataatggttt cttagacgtc
    10801 aggtggcact tttcggggaa aagtgcgcgg aacccctatt tgtttatttt tctaaataca
    10861 ttcaaatatg tatccgctca tgagacaata accctgataa atgcttcaat aatattgaaa
    10921 aaggaagagt atgagtattc aacatttcca aacaaagtta ggcatcacaa agtacagcat
    10981 cgtgaccaac agcaacgatt ccgtcacact gcgcctcatg actgagcatg accttgcgat
    11041 gctctatgag tggctaaatc gatctcatat cgtcgagtgg tggggcggag aagaagcacg
    11101 cccgacactt gctgacgtac aggaacagta cttgccaagc gttttagcgc aagagtccgt
    11161 cactccatac attgcaatgc tgaatggaga gccgattggg tatgcccagt cgtacgttgc
    11221 tcttggaagc ggggacggat ggtgggaaga agaaaccgat ccaggagtac gcggaataga
    11281 ccagttactg gcgaatgcat cacaactggg caaaggcttg ggaaccaagc tggttcgagc
    11341 tctggttgag ttgctgttca atgatcccga ggtcaccaag atccaaacgg acccgtcgcc
    11401 gagcaacttg cgagcgatcc gatgctacga gaaagcgggg tttgagaggc aaggtaccgt
    11461 aaccacccca gatggtccag ccgtgtacat ggttcaaaca cgccaggcat tcgagcgaac
    11521 acgcagtgtt gcctaaccct tccatcgagg gggacgtcca agggctggcg cccttggccg
    11581 cccctcatgt caaacgttaa acatcatgag ggaagcggtg atcgccgaag tatcgactca
    11641 actatcagag gtagttggcg tcatcgagcg ccatctcgaa ccgacgttgc tggccgtaca
    11701 tttgtacggc tccgcagtgg atggcggcct gaagccacac agtgatattg atttgctggt
    11761 tacggtgacc gtaaggcttg atgaaacaac gcggcgagct ttgatcaacg accttttgga
    11821 aacggcactg ttgcaaatag tcggtggtga taaacttatc atcccctttt gctgatggag
    11881 ctgcacatga acccattcaa aggccggcat tttcagcgtg acatcattcg gtgggccgta
    11941 cgctggtact gcaaatacgg catcagttac cgtgagctgc aggagatgct ggctgaacgc
    12001 ggagtgaatg tcgatcactc cacgatttac cgctgggttc agcgttatgc gcctgaaatg
    12061 gaaaaacggc tgcgctggta ctggcgtaac ccttccgatc tttgcccgtg gcacatggat
    12121 gaaacctacg tgaaggtcaa tggccgctgg gcgtatctgt accgggccgt cgacagccgg
    12181 ggccgcactg tcgattttta tctctcctcc cgtcgtaaca gcaaagctgc ataccggttt
    12241 ctgggtaaaa tcctcaacaa cgtgaagaag tggcagatcc cgcgattcat caacacggat
    12301 aaagcgcccg cctatggtcg cgcgcttgct ctgctcaaac gcgaaggccg gtgcccgtct
    12361 gacgttgaac accgacagat taagtaccgg aacaacgtga ttgaatgcga tcatggcaaa
    12421 ctgaaacgga taatcggcgc cacgctggga tttaaatcca tgaagacggc ttacgccacc
    12481 atcaaaggta ttgaggtgat gcgtgcacta cgcaaaggcc aggcctcagc attttattat
    12541 ggtgatcccc tgggcgaaat gcgcctggta agcagagttt ttgaaatgta aggcctttga
    12601 ataagacaaa aggctgcctc atcgctaact ttgcaacagt gccctgataa atctggagcc
    12661 ggtgagcgtg ggtctcgcgg tatcattgca gcactggggc cagatggtaa gccctcccgt
    12721 atcgtagtta tctacacgac ggggagtcag gcaactatgg atgaacgaaa tagacagatc
    12781 gctgagatag gtgcctcact gattaagcat tggtaactgt cagaccaagt ttactcatat
    12841 atactttaga ttgatttaaa acttcatttt taatttaaaa ggatctaggt gaagatcctt
    12901 tttgataatc tcatgaccaa aatcccttaa cgtgagtttt cgttccactg agcgtcagac
    12961 cccgaagccg ataaaaaggt aaaagaggca gaggcaaata aagatgattt tgtgacttat
    13021 aacccgcctc atgaatatgg ctccgggtgg caggatcagg ttcgctatct tgataaggat
    13081 attcagaatc agaatgagaa attaaaagct gcccagacat ctttaaacga aatgaatgaa
    13141 tccttatcca gggataaggc tgcgctttcc ggggcgatgg agagccggaa acaaaaggag
    13201 aaaaaagcga aggatgcaga aaataaatta aatgaggaaa agaaaaaacc tcgtaaggga
    13261 actaaagatt acggccatga ttattttcct gatcccaaga ctgaagatat taaggggttg
    13321 ggagagttga aagagggtaa acctaaaacc cctaaacaag gtggtggtgg taagcgggcc
    13381 cgatggtatg gtgataaaaa gcgtaaaatt tatgaatggg attcccagca cggtgagctt
    13441 gaagggtacc gcgccagtga tggcgaacac ctcggggcat tcgatccaaa aacgggtaag
    13501 caggttaaag ggccggatcc aaaacgaaac attaaaaaat atctttaaga ggtaaatatg
    13561 gggcttaaat tacatattca ttggtttgat aagaaaaccg aagagtttaa aggtggtgaa
    13621 tactcaaaag acttcggtga tgatggttct gtcattgaaa gtctggggat gcctttaaag
    13681 gataatatta ataatggttg gtttgatgtt gaaaaatcat gggtttcgat attacagcca
    13741 cactttaaaa atgtaatcga tattagtaaa tttgattact ttgtatcctt tgtttaccgg
    13801 gatggtaact ggtaagcaaa agttatcaag gatgatttga aatacagact tccggtgttc
    13861 agggatgaat accggggttt ttaaatacag ggaaggtata tgaaaaaggt aaaggttgtt
    13921 tttcttttta tattgatttt ttcaggcttt cttctggtcg catgtcaggc aaactatatc
    13981 cgggatgttc agggtggaac ggtggcacca tcgtcctcct ctgaactgac ggggatcgcg
    14041 gttcagtaga aaagatcaaa ggatcttctt gagatccttt ttttctgcgc gtaatctttt
    14101 gccctgtaaa cgaaaaaacc acctggggag gtggtttgat cgaaggttaa gtcagttggg
    14161 gaactgctta accgtggtaa ctggctttcg cagagcacag caaccaaatc tgtccttcca
    14221 gtgtagccgg actttggcgc acacttcaag agcaaccgcg tgtttagcta aacaaatcct
    14281 ctgcgaactc ccagttacca atggctgctg ccagtggcgt tttgcgtgct tttccgggtt
    14341 ggactcaagt gaacagttac cggataaggc gcagcagtcg ggctgaacgg ggggttcttg
    14401 cttacagccc agcttggagc gaacgaccta caccgagccg agataccaga gtgtgagcta
    14461 tgagaaagcg ccacacttcc cgcaagggag aaaggcggaa caggtatccg ggaaacggca
    14521 gggttggaac aggagagcgc aagagggagc gattcatcgg aaacggtgat gatctttaag
    14581 tcctgtcggg tttcgccact cctgactgat tcatggttga gccaccggct cccacagatg
    14641 caccgaaaaa gcgtctgttt atgtgaactc agtcaggagg gcggagccta tggaaaaacg
    14701 ccacctgcgt ggccttgccg ttttgcctca catgttagtc ccctgcttat tcacggaatc
    14761 tgtgggtaac tttgcatgtg tccgcagcgc ccgccgcagt ctcacggccg gagcgtagcg
    14821 accgagtgag cgaggaggcg caatttcccc ggcacctaca agacggacac cggacgcgct
    14881 gatgtggcat attgtcccct gattaagtct ttatattccc tgataataaa ttaccaggat
    14941 aggtgaatca tatcggtttt tcgctgaaca ttttacgtta acctatctct gttgcttttt
    15001 tctccttacg gagaaataca ggtcatcccc gcgagggcgt ggctgacctc agggggatat
    15061 cccctgctta cgctggctgg acgccaccga cgcacggtct ctccccctct ttctggctcc
    15121 gtccggctgg acgccggcca cgccagaaat tcacccggcc cccgtcaggc tcacgcctga
    15181 ccacccacaa aaatccacgg tgctggacgc acctggcgaa gcagcaaagc tgctcctgat
    15241 tttgcgggtg gtcagccgct cgctatggcg aactctgacg ggggccggaa caccggaaaa
    15301 gaccgcactg gggtgccgcc ttttcctctc acacgctggg gcgtgctcgt tgttcctccg
    15361 gggctgcgcc ttttccgcat ggggcggaaa gaggctggcc tccgtggtga aagctgaacg
    15421 caatcaccac ggacgtgacc gccgccgcca tgccttgggg catgtccgcg gcttgtgcag
    15481 cgggggctgc acatcacgcc ggcaaaccat cgtctgaagg agagagaaca tgtttaatac
    15541 ggattcgctt gcctggaagt ggcacattcc ggagctggcc cggcagattt atccgtgggt
    15601 cagctggctg taccaggagt attacggtct ggccggggct ttcctagtta tcggcctgtt
    15661 tttcggtctg gctgaacttt gggccggacg gatgcgtttt gtggggctga gtcataagga
    15721 gcgacgggag tatgccgatc gctataagcg cgataataaa cggccagcgc cattttcggt
    15781 gctggcctcg ctggattcgc ccgggcggat ggtcagggca cgtcgacatg tctggaacta
    15841 cgcgtactgg ctgaccggcg cggccggtct ggcccttctg ggggggctgg ttgtcgccgt
    15901 gtttatcgag agctggggag aaaccgtcct gcgtccggac ctctacgcaa acgcagatta
    15961 ttacctgctg cagccggcta acctgttcgg gattgcctgg tgcgcgggcg ggctggctgt
    16021 cgggattgtg ttggcgcggc tgctggcgtt cctgctgctt gacggtcatt ttgcggctgc
    16081 tgacgaggcg gtgaacgcga aactgaatca ggagagccgg cgcagcagcc agcggacagg
    16141 agagatgacc gacgtgcgcc acctgcattt cggggagccg gtaccggtta atgcgctggc
    16201 cgatttttcc tcggagcagg cccggcagga gcaggcggtg tttctgggta aggatgagca
    16261 gggcaagccg gtgctggttc cgcgtgatac ctggcgcaag accaacattc agatcctcgg
    16321 cctgcccggg agcggcaaga gcgtgatggc caccaacgcg ctcattcgct gcgtacgcga
    16381 tttcggggac gcggtggtgt acttcgaccc caaaggggac gcatgggcgc cgcacgtctt
    16441 ccgggcgcac tgtccggact tcaccctgct ggatctgcgg ccggggaaac cggcgcagct
    16501 gaatctgttc cgcgatctcg accagtacgc gctgaaaaac ctgctgattg ccgggcttaa
    16561 cctgggcgag accggcgacg tggcggacca ctaccgcatc agcgagcaga aagcggcgaa
    16621 gctgattgcg gagcagtttc cgcagggggc aaacattcag caggtgctgg cggcggcgta
    16681 cgcgctgccg gaggccctga aaaaggacgt gaaggggttg atcactaggc tggaaaacgt
    16741 cgctgacctg agcgtcctgc agacggacag tggcatcgat gtggcgggga ttatcaacgg
    16801 cggcggctgc ctgtacgtta tcggctcgat ggacgacgag gcggtgatcc gtgtgcaaaa
    16861 aatgctgttt gcccgctgcg cgcaaatcat cattgcgcgg gacgagttcc gggagtggcc
    16921 acacgtcagc gtgatgctcg atgaaattaa atatctgctg tcgaagtatg tactgaacgc
    16981 actggggacg ctgcgcagcc gggactgcaa tctgttgctc gcgcaccagt cgctgggcga
    17041 tttcgggcag tgcgggcagg atctgcccgc tgaatttgtg aaaaccacgg tactggataa
    17101 cacgccgatc cgctggtttt accgggcggc cagcctggag tccgcgcagt gggcggcggg
    17161 gcagaccggg gaaatcaggg tggacgtgga gcgccgccgt gccagccggg aggcggggaa
    17221 cgtggagcat atcagcgggg acagcttcat ccagaaggag gcgcggccgc tgtttgacgt
    17281 gaacaccctg caacacctgc cggacgggtt cgcggtcatg accgggctgg gtgtggcccg
    17341 gatggcgttc agcagtccgc tgcgggttga gcgccgggaa atcccgttgc agcgtttccc
    17401 ggtgctggcg aaaaccgatc ccctggcgga gttccggccc ccggccgacg gcggcgggcc
    17461 gaaagcggat gatgattttg cggggattta ctgatggcgc tggagctgta caaggggttc
    17521 taagcgggaa tcccagaaaa ttccgtcatt ccgtatgatg aaaattcagt cgactcctcg
    17581 cttgacgtga cgagcgccaa aagcctgccg catctgcctg gcgcgctcga gctcatcgcc
    17641 atgcaaatac atcgacgtcg tggcgatcga cgcatggcgt aggttgtcgc gcaccgcggt
    17701 gagctgagct ccccgggcca acgcatggct ggcatgactg tgacgcatcc aatgaggcgt
    17761 ggcacggcgc agcttttcgg cggcgaccgg atgatcggcc tcaatggcct cagcggcttg
    17821 cgtaaagaat cttcgcaaca cgcaccaaag gtgagggccg gtgatgccgg cattaccgtc
    17881 ttccccaaga ctgcccacca ggggcgtttt cggattccac cgttcccggc tgactggcag
    17941 ttgacgctgt gccaagtatt ggtccagcgc cgtatacgcg agcggcggca aggccacctt
    18001 acctggtttg ccacctttgc caaccaaatg cagccagtgg tcaccgtgct cgtcgaggcg
    18061 gacattaccc aggacggcgc cgaccagttc gctagcgcgc aggcccgtgg catagccgaa
    18121 gtcgagcatg aagcgcaggc gttgtgctgc cggctcggac cagccgtagg accattccag
    18181 gccgtctgca atggcgcgca gcagtagcca ttctccctcg gtaaagcctc gcgccgtatc
    18241 cagtgcgggc cgcaaggcgt gaccgcgtac cttgacgccg gcgaaagggt tggccagcac
    18301 atagcgctgc tcgatgagcc accggaacag cgccgagagc accgtcagcg catacgctgc
    18361 cgagcgtgcg gacaagccgc ccgagaaggg gcgccattcc accgaatcgc gtggtcgagg
    18421 tggccccacc caacgctcgc gcggggtcgg gtgccggaca aaggcccggt acgcgattgc
    18481 atcgtccgtg gtcagggatg atagcgcccg tccgcgttcg acgatggccc acaggattag
    18541 ccgcgcagcc tccttgcgat aggcgcgctg tgtggcgaca gtctcgtgca gcgccagcca
    18601 ggcctgcacg gcctcgtagt cgttggtcgc attcagcgtg caagcgttgc gcggggcccg
    18661 gaaattgccc tgcgagccgt cgacttcgtt cggcagacgc aactgctccc acggcacgat
    18721 gccgctgggc tgaataatcg ggatcagggc ccgggcgcgc tcggtgagct gcggatgtgc
    18781 ggcaaagaaa gcctcgacct gccgggcgcc tgtcatgccg agtccctcga tggctttcca
    18841 ccagccacgc cggcggggaa tgcgcacggt cagcgccgag agggtgtgga taccgtacgc
    18901 ctgcagtgcc ctgacggtcc tcggagacag ccactggtcg atgctgtcgc tgatctgggg
    18961 cttcggcgcc ggcagcgtgg gcaagagccg gatcgcgcgt tcgacggcac ccgcgcgccc
    19021 ctgtcgctct tcgggggcgt gctggaacac gtcggccaga tccggccggt ggcggctgtt
    19081 ggcgaaaacg atgagctggc ggcggatatg ccccagcatc cctcgcgctg attgaccggc
    19141 ggccttgcgt gccgccaggt agtgttcaac ggccgcgcga gagctgagtc ccgcgtacca
    19201 gccgcgcaag gcagccagcg aatccgcatc gggaaagccg actggggtag aactcgaagc
    19261 cgtagtctgg cccgttttca tatggacagg ttgcgattcg aaaagcgagt aacgcgataa
    19321 taacgattat ttcagtagaa tcgaaaatgc cccatgtttc tacgaaacct caagatagca
    19381 agaacgggcc atgagcaaga agaacaagct actcagcgtc ctatccgacg ccgaacagga
    19441 ggccttgtat ggcctgccgg agttcgatga tgcgcagcag ctggaatatc tggctgtgac
    19501 agaaaccgag ttggcgcttg ccaacagccg gcccagtctt catgccaagg tctattgcct
    19561 cttgcagatc ggctacttca aggccaagca tgccttcttc agtttcgact gggacgaagt
    19621 cgaggacgat tgcgctttcg tgctgagccg ctatttccac ggcgaggtgt tcgaacccaa
    19681 ggcgatcacc aagcatgaac gctacaccca gcgcgagcag atcgccaaac tattcggcta
    19741 ctggccgtgg tcggccgcct tcctgccgca gctcgagcag caggccgcac ggaccgtgcg
    19801 gcgtgacgta acgccggggt tcgtcgccgc cgagctgatc gtctggctca atgagcacaa
    19861 gattatccgg cccggctata cgaccttgca agagttggtc agcgaaacgc tatccgccga
    19921 gcgccggcgc ctgggcaatc tgctggagca agcgttggac gaatctgcca aggccgcgct
    19981 gagccagctt ctggtccgtg atgacaccct gtcgcaactg gcggcgctca agcaggacgc
    20041 caagaatttc ggctggcgcc agatggtccg cgagcgcgaa aagcgcgcca cgctggagcc
    20101 gctgcacgca atcgccaaga cactgctgcc taaactcgac gtctcgcagc agaacctgct
    20161 gtactacgcg agcctggcaa acttctacac cgtccacgac ctgcgcaatc tgaaggccga
    20221 tcagacccaa ctctacctgc tgtgctatgc ctgggtacgc taccggcagc tctccgacaa
    20281 cctggtcgat gcgatggcgt accacatgaa gcagttggag gacgaaagca gcgctggtgc
    20341 caaacaatcc tttgccgacg agcaggtgcg ccgtcagcag gaaacgccgc gggtaggccg
    20401 cctgctgtca ctctacgttg atgatagcgt ggccgatccc acgcccttcg gcgaggtgcg
    20461 gcagcgcgcc tacaagatca tgcctcgcga tacgctgcaa accacggcgc agcgtatgag
    20521 cgtgaagccg gcgagcaagc tggccttgca gtggcaggcg gtggacgggc tggccgaccg
    20581 catgcgccgc catcttcgtc cactgtacgt tgcgctcgac ctctccggct ccaatccaga
    20641 cagtccatgg cttgccgcgc tggcctgggc caaaggtgtt tttgccaagc agcagcggct
    20701 gtcgcaacgg ccactcgacg agtggcccgc ggcgacactt ccgaaacgct tgcggccgta
    20761 cctgctgacc ttcgacgccg acggtaaacc aaccggcctg cacgctgacc gctacgagtt
    20821 ctggctgtac cgccagatca ggaagcgtct ccaatcgggt gaactctacc tcgacgacag
    20881 cctgcaacac cggcacttct cagatgaact ggttgagatg gacaggaaga tcgatgtgct
    20941 cgcaaaaatg gagatcccct tcctgcagca acccgtccat gcccaactcg atgcgctgac
    21001 tgccgaactg cgcacgcagt ggctggcgtt caaccgcgag ctgaaacagg gcaagctgac
    21061 gcacctcgaa tacaacaagg acacgcagaa actgacctgg cgcaagccca agagcgagaa
    21121 tgagaaagcg cgcgaaaagg cattctacga gaagcttccg ttctgcgacg tggccgacgt
    21181 gtttcgcttc gtcaacgacg agtgcaagtt tctgtcggcg ttcacgccca tgcagccgcg
    21241 ctacgcgaag aaggtcgccg acgctgacag cctgatggcg gtcatcatcg cgcaagcgat
    21301 gaaccacggc aaccacgtca tggcgcgcac cagcgacatc ccgtaccacg tgctggatag
    21361 cggctaccag cagtacctgc gccaggcaac gctgcacgcg gccaacgact gcatcagcaa
    21421 cgccatcgcc acgctaccga tcttcccata ctactcgttc gacctcgaaa cgctgtacgg
    21481 tgccgtcgac gggcagaaat tcagcgtcga acggccgacc gtgaaggcgc gctattcgcg
    21541 caagtacttc gggcgcggca agggcgtggt cgcctacacg ctgctgtgca accacatccc
    21601 gctcaacggc tacctgatcg gcgcgcacga ctacgaggcc caccacgtgt tcgacatctg
    21661 gtatcgcaac acgtcggaca tcatgccgac cgcgatcacc ggcgacatgc acagcgtcaa
    21721 caaggccaac ttcgccatcc tgcattggtt tggccggcgg ttcgagccgc gcttcaccga
    21781 cctcaacgcg caattgaaag aactctactg cgctgacgat ccagcacagt atcaggcgtg
    21841 cctgattcgg ccagtcggga aaatcgactg cgatctcatc catcgcgaga agccgaacat
    21901 cgaccggatc gtcgccacac tcgggctgaa ggaaatgacg cagggcacgc tgatccgcaa
    21961 gctgtgcacc tacaccacga cgaacccgac gcggcgcgcg atcttcgagt tcgacaagct
    22021 catccgcagc atctacacgc ttcgctacct gcgcgatccg caactggaac gcaacgtgca
    22081 ccgctcgcaa aatcgcctcg agtcctacca tcagctacgc tcggccattg cccaggtcgg
    22141 cggtaagaag gaactgaccg gtcgcaccga cattgaaatc gagatcagca accagtgcgc
    22201 acggctgatc gccaacacga tcattttcta caactcggca atcttgtcgc ggctggtgac
    22261 caagtacgag gcggccggca acagcaaggc gctggcactc atcacaaaaa tttcgcctgc
    22321 ggcatggcgg cacatcctgc tcaacgggca ctacaccttt caaagcagcg gcaagacgat
    22381 cgatctcgat gcgatcgtcg caggcctgga actggagtga cggaattttc agcggttccg
    22441 tgttagcagc agtgtaaaac tgacccaccc cagcgaagta aaactgatcc acctgggcta
    22501 gtttggcggc cttttcgagg ccgtcgatgt tgacccagga gcaaaccgtg gaaatcagag
    22561 ttcttgcccg acagggccac tccatccggc acatcgcccg cacgttgggg gtctcgcgca
    22621 ataccgtgcg ccgctacctc cgcgatccgt cggtagcgcg ataccagccc cgtgaaccac
    22681 gccccaccaa actggggcca tttgaatctt atctgcggca acgggtcgag caggcccacc
    22741 ccatctggct gcctgccacc gtcctgaatc gggaaatccg cgctcaaggg tatggcggcg
    22801 gtctctcgtt attgcgcgcc ttcctcgcca cgctcaagcc cgcccgccgc gaagcaggtc
    22861 cggccgtccg tttcgagacc gagcccggac ggcagttgca ggctgatttc gtggtcttgc
    22921 gccgggccag atcccccatg tcggccttcg tcgccacgct gggatacagc cgcatgacgt
    22981 ttgtcacctt cgtaccggac gaatccttcg agtccgtgcg ggactccctg ttgctggctt
    23041 ttgactatct gggcggtgtg ccccgcgagg tgttgttcga caacatgaag accgtggtgc
    23101 tggaacgcga tgcctacggt gacggcaagc accgttttca ccccggcttg cttcaactgg
    23161 ccgatgacct ggggttccgg atccggctgt gtcgcccgta tcgggcccag accaaaggca
    23221 aggtcgagcg cttcaatcgc tacttccgcg agagcttcta caacccgttg ctgacccgga
    23281 tgaagggcac ggggctgctg ctcgattgtg ctgctgccaa ccgacgcgtc cgtgactggt
    23341 tggcagacga ggcgaatgtg cgggtccacg ccaccctgaa cgagcgcccc atcgaccgtt
    23401 ggcggcagga gcgggaacac ctgcaaccct tgccatcccg tgtgcggcgc gacgaggccc
    23461 ccctgctgga taacagtctc cgcccggtac cactggaatc tctccagcac ccactgtctg
    23521 tctatgacgc aattggggag gcctgccg
//
