LOCUS       NZ_CP090452            37779 bp    DNA     circular CON 08-DEC-2023
DEFINITION  Escherichia coli strain PT62 plasmid pPT62-37kb, complete sequence.
ACCESSION   NZ_CP090452
VERSION     NZ_CP090452.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN24648241
            Assembly: GCF_021441965.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37779)
  AUTHORS   Lu,X. and Li,R.
  TITLE     Coexistence of tet(X4), mcr-1 and blaNDM-5 in ST6775 Escherichia
            coli isolates of animal origin in China
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 37779)
  AUTHORS   Lu,X. and Li,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JAN-2022) Colloege of Veterinary Medicine, Yangzhou
            University, Shuangqiao Street, YangZhou, JiangSu 225000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology :: Illumina HiSeq; QitanTech nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/08/2023 10:05:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,839
            CDSs (total)                      :: 4,723
            Genes (coding)                    :: 4,444
            CDSs (with protein)               :: 4,444
            Genes (RNA)                       :: 116
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 279
            CDSs (without protein)            :: 279
            Pseudo Genes (ambiguous residues) :: 0 of 279
            Pseudo Genes (frameshifted)       :: 78 of 279
            Pseudo Genes (incomplete)         :: 186 of 279
            Pseudo Genes (internal stop)      :: 44 of 279
            Pseudo Genes (multiple problems)  :: 29 of 279
            Pseudo Genes (short protein)      :: 4 of 279
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP090452.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..37779
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="PT62"
                     /isolation_source="pigeon"
                     /db_xref="taxon:562"
                     /plasmid="pPT62-37kb"
                     /geo_loc_name="China: Jiangsu"
                     /lat_lon="31.91 N 120.26 E"
                     /collection_date="2021-06-17"
                     /collected_by="Xiaoyu Lu"
     gene            1..1011
                     /locus_tag="LZ175_RS23840"
                     /old_locus_tag="LZ175_23830"
     CDS             1..1011
                     /locus_tag="LZ175_RS23840"
                     /old_locus_tag="LZ175_23830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017900946.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="WP_000200070.1"
                     /translation="MTSENNSLLLNLQEVDKTTGEVVKLDVNSTSTVQPVALMRLGLFV
                     PTLKSTGKSKANRKNVTDATEELVQLSIAKSEGYTDVKITGSRLDMDTDFKVWLGIIRS
                     MSEYGVKSDTLELSFVEFVKMCGFDSRRSNKKMRDRISNSLFKLASVTLKFQSETKGWT
                     THLVQSAYYDINEDIVEIKAEPKLFELYHMDRRVLLRLKAIDALQRKESAQALYTYIES
                     LPQNPAPISMKRMRDRLNLTSNVYTQNHTVRKAMEQLRDIGYLDYTEFKRGRATYFSVH
                     YRNPKLISGPVKVPRKEEEEKAPEQNYDEVIKALKAAGIDPLKLAEALSAMKPEN"
                     /name="RepB family plasmid replication initiator protein"
     gene            1205..2173
                     /locus_tag="LZ175_RS23845"
                     /old_locus_tag="LZ175_23835"
     CDS             1205..2173
                     /locus_tag="LZ175_RS23845"
                     /old_locus_tag="LZ175_23835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611102.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS903B family transposase"
                     /protein_id="WP_077816224.1"
                     /translation="MKDQITYLPDNADRSVAKQKFKITNWPTYNKAPINRGSITFWLDD
                     EAIQAWYESATPSSRGRPQRYSDLAITTVLVIKRVFRLTLRAAQGFIDSIFSLMNVPLR
                     CPDYSCVSRRAKSVNVSFKTPTRGEIAHLVIDSTGLKVFGEGEWKVKKHGQERRRIWRK
                     RHLAVDSKTHEIICADLSLNNVTDSEAFPGLIRQTHRKIRAASADGAYDTRLCHDELRR
                     KKISALIPPRKGAGYWPGEYADRNRAVANQRMTGSNARWKWTTDYNRRSIAETAMYRVK
                     QLFGGSLTLRDYDGQVAEAMALVRALNKMTKAGMPESVRIA"
                     /name="IS5-like element IS903B family transposase"
     gene            complement(2340..2630)
                     /locus_tag="LZ175_RS23850"
                     /old_locus_tag="LZ175_23840"
     CDS             complement(2340..2630)
                     /locus_tag="LZ175_RS23850"
                     /old_locus_tag="LZ175_23840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001471781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001471781.1"
                     /translation="MKIVTNQLSDVNRKLDYLFDRASDADFGSLRDELKAITETLSGVT
                     FPPAGQMMLHESLAIETLILLRSIAEPGKTKAAKAEVERNGYKVWEPKKER"
                     /name="hypothetical protein"
     gene            3289..3624
                     /gene="stbA"
                     /locus_tag="LZ175_RS23855"
                     /old_locus_tag="LZ175_23845"
     CDS             3289..3624
                     /gene="stbA"
                     /locus_tag="LZ175_RS23855"
                     /old_locus_tag="LZ175_23845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006796897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein StbA"
                     /protein_id="WP_001039462.1"
                     /translation="MNKPADLKPRNLSAAVRLRLNEIENWLDRGLTRHEIAEILDSEYS
                     FSVTAKGLEMALYRTRKNRKNVLYNTQPSEPEAQESEKAESPGIIDKEFFNKIGEDFNP
                     KKFNKKF"
                     /name="stbA"
     gene            3633..>3818
                     /locus_tag="LZ175_RS23860"
                     /old_locus_tag="LZ175_23850"
                     /pseudo=""
     CDS             3633..>3818
                     /locus_tag="LZ175_RS23860"
                     /old_locus_tag="LZ175_23850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011279206.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /name="plasmid stabilization protein"
     gene            complement(3835..4418)
                     /locus_tag="LZ175_RS23865"
                     /old_locus_tag="LZ175_23855"
                     /pseudo=""
     CDS             complement(3835..4418)
                     /locus_tag="LZ175_RS23865"
                     /old_locus_tag="LZ175_23855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            4952..5707
                     /gene="repE"
                     /locus_tag="LZ175_RS23870"
                     /old_locus_tag="LZ175_23860"
     CDS             4952..5707
                     /gene="repE"
                     /locus_tag="LZ175_RS23870"
                     /old_locus_tag="LZ175_23860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepE"
                     /protein_id="WP_000807690.1"
                     /translation="MAEIAVINHKKRKNSPRIVQSNELTEAAYSLSRDQKRMLYLFVDQ
                     IRKSDGSLQEHDGICEIHVAKYAETFGLTSAEASKDIRQALKGFAGKEVVFYRPEEDAG
                     DEKGYESFPWFIKRAHSPSRGLYSVHINPYLIPFFIGLQNRFTQFRLSETKEITNPYAM
                     RLYESLCQYRKPDGSGVVSLKIDWIMERYQLPQSYQRMPDFRRRFLQASVDEINSRTPM
                     RLSYIEKKKGRQTTHIVFSFRDITSMTIE"
                     /name="repE"
     gene            5976..>6321
                     /locus_tag="LZ175_RS23875"
                     /old_locus_tag="LZ175_23865"
                     /pseudo=""
     CDS             5976..>6321
                     /locus_tag="LZ175_RS23875"
                     /old_locus_tag="LZ175_23865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            6832..6972
                     /locus_tag="LZ175_RS23880"
                     /old_locus_tag="LZ175_23870"
     CDS             6832..6972
                     /locus_tag="LZ175_RS23880"
                     /old_locus_tag="LZ175_23870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004031751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_160784086.1"
                     /translation="MAENGYGLAGPGMDKVKSINQYRLTPGFGGFTPVSYATMECRLPC
                     R"
                     /name="hypothetical protein"
     gene            7045..7314
                     /gene="yacA"
                     /locus_tag="LZ175_RS23885"
                     /old_locus_tag="LZ175_23875"
     CDS             7045..7314
                     /gene="yacA"
                     /locus_tag="LZ175_RS23885"
                     /old_locus_tag="LZ175_23875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015056448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin YacA"
                     /protein_id="WP_000079938.1"
                     /translation="MAQVNMSLRIDAELKDAFMAAAKSMDRNGSQLIRDFMRQTVERQH
                     NTWFRDQVAAGRQQLKRGDVLPHDMVESSAAAWRDEMSRKVADK"
                     /name="yacA"
     gene            7314..7592
                     /gene="yacB"
                     /locus_tag="LZ175_RS23890"
                     /old_locus_tag="LZ175_23880"
     CDS             7314..7592
                     /gene="yacB"
                     /locus_tag="LZ175_RS23890"
                     /old_locus_tag="LZ175_23880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013009346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin YacB"
                     /protein_id="WP_244578848.1"
                     /translation="MEIFWTMLASQDRKRIREYIAEQNLMVAIELDERIGYSASSLAGQ
                     PYKGRNGRVEGARELVIHPHFVLVYEVDSPWGKVYILRVLHTAQKWP"
                     /name="yacB"
     gene            complement(7628..>9379)
                     /locus_tag="LZ175_RS23895"
                     /old_locus_tag="LZ175_23885"
                     /pseudo=""
     CDS             complement(7628..>9379)
                     /locus_tag="LZ175_RS23895"
                     /old_locus_tag="LZ175_23885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138014.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element TnAs1 family transposase"
                     /name="Tn3-like element TnAs1 family transposase"
     gene            9383..9775
                     /locus_tag="LZ175_RS23900"
                     /old_locus_tag="LZ175_23890"
     CDS             9383..9775
                     /locus_tag="LZ175_RS23900"
                     /old_locus_tag="LZ175_23890"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013053.3"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="WP_001351729.1"
                     /translation="MLFPNFSLGEEYEHAPPATNRQISPYLPSGRFRTGLPVEGLAIER
                     GDLFYACPRASVFYGTALDADLRTRGVSTLVMAGISTTGVVLSSVAWASDADYDVRLVQ
                     DCCYDPDRDAHEALLRSGFGGRVQVV"
                     /name="isochorismatase family cysteine hydrolase"
     gene            9913..10797
                     /locus_tag="LZ175_RS23905"
                     /old_locus_tag="LZ175_23895"
     CDS             9913..10797
                     /locus_tag="LZ175_RS23905"
                     /old_locus_tag="LZ175_23895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058717.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="WP_000058717.1"
                     /translation="MSLRTPDLLFTAIAPAIWGSTYIVTTQYLPNFSPMTVAMLRALPA
                     GLLLVMIVRQIPTGIWWMRIFILGALNISLFWSLLFISVYRLPGGVAATVGAVQPLMVV
                     FISAALLGSPIRLMAVLGAICGTAGVALLVLTPNAALDPVGVAAGLAGAVSMAFGTVLT
                     RKWQPPVPLLTFTAWQLAAGGLLLVPVALVFDPPIPMPTGTNVLGLAWLGLIGAGLTYF
                     LWFRGISRLEPTVVSLLGFLSPGTAVLLGWLFLDQTLSALQIIGVLLVIGSIWLGQRSN
                     RTPRARIACRKSP"
                     /name="EamA family transporter"
     gene            complement(10829..12028)
                     /gene="tet(A)"
                     /locus_tag="LZ175_RS23910"
                     /old_locus_tag="LZ175_23900"
     ARG             complement(10833..12028)
                     /name="tet(A)"
                     /gene="tet(A)"
                     /gene_name="tetracycline efflux MFS transporter Tet(A)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="99.75"
                     /coverage="100.0"
     gene            12134..12784
                     /gene="tetR(A)"
                     /locus_tag="LZ175_RS23915"
                     /old_locus_tag="LZ175_23905"
     CDS             12134..12784
                     /gene="tetR(A)"
                     /locus_tag="LZ175_RS23915"
                     /old_locus_tag="LZ175_23905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional repressor
                     TetR(A)"
                     /protein_id="WP_050858789.1"
                     /translation="MTKLQPNTVIRAALDLLNEVGVDGLTTRKLAERLGVQQPALYWHF
                     RNKRALLDALAEAMLAENHTHSVPRADDDWRSFLIGNARSFRQALLAYRDGARIHAGTR
                     PGAPQMETADAQLRFLCEAGFSAGDAVNALMTISYFTVGAVLEEQAGDSDAGERGGTVE
                     QAPLSPLLRAAIDAFDEAGPDAEFEQGLAVIVDGLAKRRLVVRNVEGPRKGDD"
                     /name="tetR(A)"
     gene            complement(12816..13058)
                     /locus_tag="LZ175_RS23920"
                     /old_locus_tag="LZ175_23910"
     CDS             complement(12816..13058)
                     /locus_tag="LZ175_RS23920"
                     /old_locus_tag="LZ175_23910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_000844627.1"
                     /translation="MKTAALDLARERQAHEAGARTRATAHERTPQQERQKAAREAERGR
                     EAWTLGQGMKKPVAGCYGRLTRWKGGGDVVYMALL"
                     /name="transposase"
     gene            complement(13116..16082)
                     /locus_tag="LZ175_RS23925"
                     /old_locus_tag="LZ175_23915"
     CDS             complement(13116..16082)
                     /locus_tag="LZ175_RS23925"
                     /old_locus_tag="LZ175_23915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138014.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element TnAs1 family transposase"
                     /protein_id="WP_001138014.1"
                     /translation="MPRRLILSATERDTLLALPESQDDLIRYYTFNDSDLSLIRQRRGD
                     ANRLGFAVQLCLLRYPGYALGTDSELPEPVILWVAKQVQAEPASWAKYGERDVTRREHA
                     QELRTYLQLAPFGLSDFRALVRELTELAQQTDKGLLLAGQALESLRQKRRILPALSVID
                     RACSEAIARANRRVYRALVEPLTDSHRAKLDELLKLKAGSSITWLTWLRQAPLKPNSRH
                     MLEHIERLKTFQLVDLPEGLGRHIHQNRLLKLAREGGQMTPKDLGKFEPQRRYATLAAV
                     VLESTATVIDELVDLHDRILVKLFSGAKHKHQQQFQKQGKAINDKVRLYSRIGQALLEA
                     KESGSDPYAAIEAVIPWDEFTESVSEAELLARPEGFDHLHLVGENFATLRRYTPALLEV
                     LELRAAPAAQGVLAAVQTLREMNADNLRKVPADAPTAFIKPRWKPLVITPEGLDRKFYE
                     ICALSELKNALRSGDIWVKGSRQFRDFDDYLLPAEKFAALKREQALPLAINPNSDQYLE
                     ERLQLLDEQLATVTRLAKDNELPDAILTESGLKITPLDAAVPDRAQALIDQTSQLLPRI
                     KITELLMDVDDWTGFSRHFTHLKDGAEAKDRTLLLSAILGDAINLGLTKMAESSPGLTY
                     AKLSWLQAWHIRDETYSAALAELVNHQYRHAFAAHWGDGTTSSSDGQRFRAGGRGESTG
                     HVNPKYGSEPGRLFYTHISDQYAPFSTRVVNVGVRDSTYVLDGLLYHESDLRIEEHYTD
                     TAGFTDHVFALMHLLGFRFAPRIRDLGETKLYVPQGVQAYPTLRPLIGGTLNIKHVRAH
                     WDDILRLASSIKQGTVTASLMLRKLGSYPRQNGLAVALRELGRIERTLFILDWLQSVEL
                     RRRVHAGLNKGEARNSLARAVFFNRLGEIRDRSFEQQRYRASGLNLVTAAIVLWNTVYL
                     ERATQGLVEAGKPVDGELLQFLSPLGWEHINLTGDYVWRQSRRLEDGKFRPLRMPGKP"
                     /name="Tn3-like element TnAs1 family transposase"
     gene            complement(16086..16646)
                     /locus_tag="LZ175_RS23930"
                     /old_locus_tag="LZ175_23920"
     CDS             complement(16086..16646)
                     /locus_tag="LZ175_RS23930"
                     /old_locus_tag="LZ175_23920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220837.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001161490.1"
                     /translation="MQGHRIGYVRVSSFDQNPERQLEQTQVSKVFTDKASGKDTQRPQL
                     EALLSFVREGDTVVVHSMDRLARNLDDLRRLVQKLTQRGVRIEFLKEGLVFTGEDSPMA
                     NLMLSVMGAFAEFERALIRERQREGIALAKQRGAYRGRKKALSDEQAATLRQRATAGEP
                     KAQLAREFNISRETLYQYLRTDD"
                     /name="recombinase family protein"
     gene            complement(16822..>17172)
                     /locus_tag="LZ175_RS23935"
                     /old_locus_tag="LZ175_23925"
                     /pseudo=""
     CDS             complement(16822..>17172)
                     /locus_tag="LZ175_RS23935"
                     /old_locus_tag="LZ175_23925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016240397.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3330 domain-containing protein"
                     /name="DUF3330 domain-containing protein"
     gene            complement(17375..18388)
                     /gene="intI1"
                     /locus_tag="LZ175_RS23940"
                     /old_locus_tag="LZ175_23930"
     CDS             complement(17375..18388)
                     /gene="intI1"
                     /locus_tag="LZ175_RS23940"
                     /old_locus_tag="LZ175_23930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 integron integrase IntI1"
                     /protein_id="WP_000845039.1"
                     /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLPTEQAYVHWVRAFI
                     RFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEI
                     GRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHG
                     TIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPR
                     AGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATPHTLRH
                     SFATALLRSGYDIRTVQDLLGHSDVSTTMIYTHVLKVGGAGVRSPLDALPPLTSER"
                     /name="intI1"
     gene            18533..19030
                     /gene="dfrA12"
                     /locus_tag="LZ175_RS23945"
                     /old_locus_tag="LZ175_23935"
     ARG             18534..19027
                     /name="dfrA12"
                     /gene="dfrA12"
                     /gene_name="trimethoprim-resistant dihydrofolate reductase
                     DfrA12"
                     /tool="amrfinderplus"
                     /drug_class="TRIMETHOPRIM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            19142..19432
                     /locus_tag="LZ175_RS23950"
                     /old_locus_tag="LZ175_23940"
     CDS             19142..19432
                     /locus_tag="LZ175_RS23950"
                     /old_locus_tag="LZ175_23940"
                     /inference="COORDINATES: protein motif:HMM:NF017990.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1010 domain-containing protein"
                     /protein_id="WP_001336345.1"
                     /translation="MFIQTAFSFSGVIQCLFCLFSGLRLHGLRRFSVFLASSPCVASAS
                     SYRFCSAVPPRWRSVFSRLAPVAKFKLSVLASGSNISVKPTRILRSAYLAR"
                     /name="DUF1010 domain-containing protein"
     gene            19438..20276
                     /locus_tag="LZ175_RS23955"
                     /old_locus_tag="LZ175_23945"
                     /pseudo=""
     CDS             19438..20276
                     /locus_tag="LZ175_RS23955"
                     /old_locus_tag="LZ175_23945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749984.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="AadA family aminoglycoside
                     3''-O-nucleotidyltransferase"
                     /name="AadA family aminoglycoside
                     3''-O-nucleotidyltransferase"
     gene            20491..21750
                     /locus_tag="LZ175_RS23960"
                     /old_locus_tag="LZ175_23950"
     CDS             20491..21750
                     /locus_tag="LZ175_RS23960"
                     /old_locus_tag="LZ175_23950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001256773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol efflux MFS transporter CmlA1"
                     /protein_id="WP_000095725.1"
                     /translation="MSSKNFSWRYSLAATVLLLSPFDLLASLGMDMYLPAVPFMPNALG
                     TTASTIQLTLTTYLVMIGAGQLLFGPLSDRLGRRPVLLGGGLAYVVASMGLALTSSAEV
                     FLGLRILQACGASACLVSTFATVRDIYAGREESNVIYGILGSMLAMVPAVGPLLGALVD
                     MWLGWRAIFAFLGLGMIAASAAAWRFWPETRVQRVAGLQWSQLLLPVKCLNFWLYTLCY
                     AAGMGSFFVFFSIAPGLMMGRQGVSQLGFSLLFATVAIAMVFTARFMGRVIPKWGSPSV
                     LRMGMGCLIAGAVLLAITEIWALQSVLGFIAPMWLVGIGVATAVSVAPNGALRGFDHVA
                     GTVTAVYFCLGGVLLGSIGTLIISLLPRNTAWPVVVYCLTLATVVLGLSCVSRVKGSRG
                     QGEHDVVALQSAESTSNPNR"
                     /name="chloramphenicol efflux MFS transporter CmlA1"
     gene            21843..22681
                     /gene="aadA1"
                     /locus_tag="LZ175_RS23965"
                     /old_locus_tag="LZ175_23955"
                     /pseudo=""
     ARG             21844..22631
                     /name="aadA1"
                     /gene="aadA1"
                     /gene_name="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA1"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            22804..23136
                     /gene="qac"
                     /locus_tag="LZ175_RS23970"
                     /old_locus_tag="LZ175_23960"
     CDS             22804..23136
                     /gene="qac"
                     /locus_tag="LZ175_RS23970"
                     /old_locus_tag="LZ175_23960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015059047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter QacL"
                     /protein_id="WP_000800531.1"
                     /translation="MKNWLFLAIAIFGEVVATSALKSSHGFTKLVPSVVVVAGYGLAFY
                     FLSLALKSIPVGIAYAVWAGLGIVLVAAIAWIFHGQKLDLWAFVGMGLIVSGVAVLNLL
                     SKVSAH"
                     /name="qac"
     gene            complement(23383..24015)
                     /locus_tag="LZ175_RS23975"
                     /old_locus_tag="LZ175_23965"
     CDS             complement(23383..24015)
                     /locus_tag="LZ175_RS23975"
                     /old_locus_tag="LZ175_23965"
                     /inference="COORDINATES: protein motif:HMM:NF013068.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="WP_020802982.1"
                     /translation="MKVPQVRGMEFYPSCIEKGMRSERALKLAIAEMYVKGVSTRRVSD
                     IVEILCGTEVSSSQVSRLAKELDEEITSWKAQPVGQIQYLVLDATYESVRVGSHVVKQA
                     LLVAIGVDYSGNRHILDAEVANSEAEVNWRSFLEGLVRRGMHGLRMITSDDHSGLRAAI
                     DAVFPGILWQRCQFHLQQNAHSYVTKKDEIPLIAADIRKVFNRNMSR"
                     /name="IS256 family transposase"
     gene            24038..24313
                     /locus_tag="LZ175_RS23980"
                     /old_locus_tag="LZ175_23970"
     CDS             24038..24313
                     /locus_tag="LZ175_RS23980"
                     /old_locus_tag="LZ175_23970"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_109023896.1"
                     /translation="MNIGLFGFTNKHYYLATKTQEKYTKPFGSDGSLSPLDYSVGIGTG
                     LELGHFQFMFGYDYPLSNSSKDPDLSQVRQHNFRASIAYSFRKLKK"
                     /name="hypothetical protein"
     gene            complement(24316..25107)
                     /gene="sul3"
                     /locus_tag="LZ175_RS23985"
                     /old_locus_tag="LZ175_23975"
     ARG             complement(24320..25107)
                     /name="sul3"
                     /gene="sul3"
                     /gene_name="sulfonamide-resistant dihydropteroate synthase
                     Sul3"
                     /tool="amrfinderplus"
                     /drug_class="SULFONAMIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(25576..25821)
                     /locus_tag="LZ175_RS23990"
                     /old_locus_tag="LZ175_23980"
     CDS             complement(25576..25821)
                     /locus_tag="LZ175_RS23990"
                     /old_locus_tag="LZ175_23980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001354008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="WP_001354008.1"
                     /translation="MKIEIMEYNPDWTKNFEEEKIKLLHFFGSHAVAIEHIGSTAIPNQ
                     RAKPVIDIFIGVSPFAELPFISAFLMQRSITTLRQI"
                     /name="GrpB family protein"
     gene            complement(25859..>26194)
                     /locus_tag="LZ175_RS23995"
                     /old_locus_tag="LZ175_23985"
                     /pseudo=""
     CDS             complement(25859..>26194)
                     /locus_tag="LZ175_RS23995"
                     /old_locus_tag="LZ175_23985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019850156.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain dehydrogenase"
                     /name="short-chain dehydrogenase"
     gene            complement(26248..26952)
                     /locus_tag="LZ175_RS24000"
                     /old_locus_tag="LZ175_23990"
     CDS             complement(26248..26952)
                     /locus_tag="LZ175_RS24000"
                     /old_locus_tag="LZ175_23990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067858.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIINATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(28542..30079)
                     /locus_tag="LZ175_RS24005"
                     /old_locus_tag="LZ175_23995"
                     /pseudo=""
     CDS             complement(28542..30079)
                     /locus_tag="LZ175_RS24005"
                     /old_locus_tag="LZ175_23995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099160.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS66-like element ISEc22 family transposase"
                     /name="IS66-like element ISEc22 family transposase"
     gene            complement(30128..30475)
                     /gene="tnpB"
                     /locus_tag="LZ175_RS24010"
                     /old_locus_tag="LZ175_24000"
     CDS             complement(30128..30475)
                     /gene="tnpB"
                     /locus_tag="LZ175_RS24010"
                     /old_locus_tag="LZ175_24000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004966400.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="WP_000612626.1"
                     /translation="MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTTLKDDPMSGHVFI
                     FRGRNGSQVKLLWSTGDGLCLLTKRLERGRFAWPSARDGKVFLTPAQLAMLLEGIDWRQ
                     PKRLLTSLTML"
                     /name="tnpB"
     gene            complement(30505..31203)
                     /locus_tag="LZ175_RS24015"
                     /old_locus_tag="LZ175_24005"
                     /pseudo=""
     CDS             complement(30505..31203)
                     /locus_tag="LZ175_RS24015"
                     /old_locus_tag="LZ175_24005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            complement(31410..32735)
                     /gene="rclA"
                     /locus_tag="LZ175_RS24020"
                     /old_locus_tag="LZ175_24010"
     CDS             complement(31410..32735)
                     /gene="rclA"
                     /locus_tag="LZ175_RS24020"
                     /old_locus_tag="LZ175_24010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414838.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reactive chlorine resistance oxidoreductase RclA"
                     /protein_id="WP_021512928.1"
                     /translation="MNKYQAVIIGFGKAGKTLAVTLAKAGWRVALIEQSNAMYGGTCIN
                     IGCIPTKTLVHDAQQHTDFVRAIQRKNEVVNFLRNKNFHNLADMPNIDVIDGQAEFINN
                     HSLRVHRPEGNLEIHGEKIFINTGAQAVVPPIPGITTTPGVYDSTGLLNLKELPGHLGI
                     LGGGYIGVEFASMFANFGSKVTILESASLFLPREDRDIADNIATILRDQGVDIILNAHV
                     ERISHHENQVQVHSEHAQLAVDALLIASGRQPATASLHPENAGIAVNERGAIVVDKRLH
                     TTADNIWAMGDVTGGLQFTYISLDDYRIVRDELLGEGKRSTDDRKNVPYSVFMTPPLSR
                     VGMTEEQARESGADIQVVTLPVAAIPRARVMNDTRGVLKAIVDNKTQRILGASLLCVDS
                     HEMINIVKMVMDAGLPYSILRDQIFTHPSMSESLNDLFSLVK"
                     /name="rclA"
     gene            32845..33543
                     /locus_tag="LZ175_RS24025"
                     /old_locus_tag="LZ175_24015"
                     /pseudo=""
     CDS             32845..33543
                     /locus_tag="LZ175_RS24025"
                     /old_locus_tag="LZ175_24015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            <33562..34407
                     /locus_tag="LZ175_RS24030"
                     /old_locus_tag="LZ175_24020"
                     /pseudo=""
     CDS             <33562..34407
                     /locus_tag="LZ175_RS24030"
                     /old_locus_tag="LZ175_24020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611553.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS911 family transposase"
                     /name="IS3-like element IS911 family transposase"
     gene            complement(34902..35873)
                     /locus_tag="LZ175_RS24035"
                     /old_locus_tag="LZ175_24025"
     CDS             complement(34902..35873)
                     /locus_tag="LZ175_RS24035"
                     /old_locus_tag="LZ175_24025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family plasmid partition protein"
                     /protein_id="WP_000817038.1"
                     /translation="MKRAPVIPRHTTHTQSTEDTSSPAPAAPMVDSLIARVGAMARGNA
                     ISLPVCGREVKFTLEVLRGDSVESASRVWSGNERDQELLTEDALDDLIPSFLLTGQQTP
                     AFGRRVSDVIEIADGSRRRKAAILTESDYRVLVGELDDEQMAALSRLGNDYRPTSAYER
                     GLRYTSRLQNEFAGNISALADAENISRKIITRCINTAKLPKSVVALFAHPGELSARSGE
                     ALQKAFADKEELLKQQAETLHDQKKAGLIFEAEEVISLLTSVLKQSPASRVNLSSRHQF
                     APGATALYKGDKMVLNLDRSRIPAECIEKIEAILKELEKPGV"
                     /name="ParB/RepB/Spo0J family plasmid partition protein"
     gene            complement(35873..37039)
                     /gene="sopA"
                     /locus_tag="LZ175_RS24040"
                     /old_locus_tag="LZ175_24030"
     CDS             complement(35873..37039)
                     /gene="sopA"
                     /locus_tag="LZ175_RS24040"
                     /old_locus_tag="LZ175_24030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid-partitioning protein SopA"
                     /protein_id="WP_000523812.1"
                     /translation="MGLMDTLNQCISAGHEMTKAIAIAQFNDDSPEARKITRRWRIGEA
                     ADLVGVSSQAIRDAEKAGRLPHPDMETRGRVEQRVGYTIEQINHMRDVFGTRLRRAEDA
                     FPPVIGVAAHKGGVYKTSVSVHLAQDLALKGLRVLLVEGNDPQGTASMYHGWVPDLHIH
                     AEDTLLPFYLGEKDDASYAIKPTCWPGLDIIPSCLALHRIETELMGKFDEGKLPADPHL
                     MLRLAIETVAHDYDVIVIDSAPNLGIGTINVVCAADVLIVPTPAELFDYTSALQFFDML
                     RDLLKNVDLKGFEPDVRILLTKYSNNNGSQSPWMEEQIRDAWGSMVLKNVVRETDEVGK
                     GQIRMRTVFEQAIDQRSSTGAWRNALSIWEPVCNEIFDRLIKPRWEIR"
                     /name="sopA"
     ARG             22805..23133
                     /name="qacL"
                     /gene="qacL"
                     /gene_name="quaternary ammonium compound efflux SMR
                     transporter QacL"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             19439..20226
                     /name="aadA2"
                     /gene="aadA2"
                     /gene_name="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA2"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             20492..21747
                     /name="cmlA1"
                     /gene="cmlA1"
                     /gene_name="chloramphenicol efflux MFS transporter CmlA1"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             21856..22634
                     /name="aadA"
                     /gene="aadA"
                     /gene_name="ANT(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.61"
                     /coverage="98.48"
     ARG             19451..20229
                     /name="aadA2"
                     /gene="aadA2"
                     /gene_name="ANT(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          2..1011
                     /name="IncFIB"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="90.307"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          4812..5198
                     /name="IncFIA"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.711"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgacgagcg aaaataatag cttacttctg aaccttcagg aagttgataa gacaaccggt
       61 gaagttgtta agctggatgt caacagcacc agtaccgtgc agccagtagc gctcatgaga
      121 ctcggtctct tcgtcccaac tctgaaatca acagggaaga gcaaggcgaa ccggaaaaac
      181 gttacagacg cgactgagga gcttgtacag ctgtccattg ccaaaagcga aggatacact
      241 gacgttaaga tcaccggttc gcgtcttgat atggacacgg attttaaagt ctggctgggg
      301 ataattcgct ccatgtcgga gtatggggta aaaagtgaca ccctggaact gtcgttcgtc
      361 gaattcgtta agatgtgcgg atttgactcc cgtcgttcaa acaaaaaaat gcgcgatcgc
      421 atcagtaatt ccctgtttaa actcgcctcg gttacgctga agttccagag cgagaccaaa
      481 ggatggacca cccatctggt gcagtcagcc tattatgaca tcaacgagga tatcgttgag
      541 atcaaggctg aacctaagct gtttgagctt taccacatgg acagaagggt acttctgcgg
      601 ctgaaagcca ttgacgccct gcagcgcaag gaatcagccc aggcgcttta tacctacatc
      661 gaaagtcttc cccagaatcc tgcacctatt tccatgaaac ggatgcgtga ccggctgaat
      721 ctcacctcaa atgtctatac gcagaaccac acggtgcgta aggcgatgga gcagctgcgg
      781 gatattggtt atctggatta cactgagttt aaacgtggcc gagccaccta tttcagcgtg
      841 cattatcgca accccaaact catcagtggt cctgtgaagg ttccgcgcaa agaggaagaa
      901 gagaaggcgc cagagcaaaa ttatgacgaa gtcattaagg cgctgaaggc tgctggcatc
      961 gatcccctta aactggccga agctctctca gcgatgaagc cagaaaattg actgtcatat
     1021 gtgatttcag gccgtgatac gcagatattg actacggtat gcgggtttaa cggcgatatt
     1081 cccaggtctg tgcactgctc cacacgtgtt aacatgccac agtcaatttt tcagtaaagc
     1141 tctatacccc ttacgaaaat ctcaatcgga tgggctttgt tgaataaatc gaacttttgc
     1201 tgagttgaag gatcagatca cgtatcttcc cgacaacgca gaccgttccg tggcaaagca
     1261 aaagttcaaa atcaccaact ggcccaccta caataaagcc cccatcaacc gtggctccat
     1321 aactttctgg ctggatgatg aagctattca ggcctggtat gagtcagcaa caccttcttc
     1381 acgaggcaga cctcagcgct attctgacct tgccatcacg actgtgctgg tcattaaacg
     1441 cgtattcagg ctgaccctgc gcgctgcgca gggctttatt gattccattt tttctctgat
     1501 gaacgttccg ctacgctgcc cggattacag ctgtgtcagc aggcgggcaa agtcggttaa
     1561 tgtcagtttc aaaacgccca cccggggtga aatcgcacac ctggtaattg attccaccgg
     1621 gctgaaggtc ttcggtgaag gcgagtggaa agtcaaaaag catggccagg aacgccgccg
     1681 tatctggcgt aagcggcatc tcgccgttga cagtaaaaca catgaaatca tctgcgctga
     1741 cctgtcgctg aacaatgtga cggactcaga agccttcccg ggtcttatcc ggcaaactca
     1801 cagaaaaatc agggcagcat cggcagacgg cgcttacgac acccggctct gtcacgatga
     1861 actgcggcgt aagaaaatca gcgcccttat ccctccccga aaaggtgcgg gttactggcc
     1921 cggtgaatat gcagaccgta accgtgcagt ggctaatcag cgaatgaccg ggagtaatgc
     1981 gcggtggaaa tggacaacag attacaaccg tcgctcgata gcggaaacgg cgatgtaccg
     2041 ggtaaaacag ctgttcgggg gttcactgac gctgcgtgac tacgatggtc aggttgcgga
     2101 ggctatggcc ctggtacgag cgctgaacaa aatgacgaaa gcaggtatgc ctgaaagcgt
     2161 gcgtattgcc tgaaaacaca acccgctacg ggggagactt acccgaaatc tgatttattc
     2221 aacaaagccc cgttgatgcg tcaataccgt aggtaaattt agcaactaga aaccatacca
     2281 ttattggcgg caaagtaatt gcaaataaaa atgctaagcc tctttctcta tcgtccattt
     2341 cagcgctcct tttttggttc ccagacttta tagccgttac gttcaacctc tgcttttgcc
     2401 gctttggttt tacccggttc tgctatcgaa cgtaggagga tcagcgtttc aatagcgagt
     2461 gattcatgca acatcatctg tcctgccggt gggaatgtta cgccagatag cgtttcggtt
     2521 attgccttca gctcatcgcg cagtgagcca aaatccgcat ctgaagcacg gtcaaaaagg
     2581 taatccagtt tgcgatttac gtcgctcagc tggttggtaa ctattttcaa cccggactcc
     2641 agatcacctg ggccagcttc aaggcagcgc cgcagatact ctgaccgatt accacctgaa
     2701 acctggtcta tataggccaa aagttcatct gatacttttg cggttattgt tggcattcag
     2761 ccctcacttt gtgcattttt taaacgaaaa aagggtgtct aatacggtga aatcatagta
     2821 ttaccaaagt aataaataaa aaatgtttta aatcagtaag ttagattaga tttgtaatac
     2881 ctgggtaata ccgcagcatg attaaacttg gtttttttct tttaaatcag tgagatagcg
     2941 tgatttatca cgctgcgtta ggtgtatagc aggtaacggg ataaaaaatc atcttttttt
     3001 ggtagggcga tcaccgtagg ttaagggtca tttggctaaa aagcgtccta ttctttgatg
     3061 gtcatgcttg catgaccatc tgagcaacca aaactacaga taaactacaa aaaacgtttt
     3121 gccttagtgt tggcagacta caaatagact acaataagac tacaaagaaa ctacaaaaac
     3181 cgtgacagac tacaaagaga ctacaagaaa actacagata aactacaaaa ctcgattgac
     3241 cccttcttac gagtgttgta gagtcatttt catacaacgg agggggttat gaataaacca
     3301 gcagatctga aaccccgcaa cttatcggct gctgtcagat tgcgcctaaa tgaaatcgag
     3361 aactggctgg acagagggct aacgcggcat gaaattgctg aaatcctcga cagcgaatac
     3421 agcttttcgg taacagccaa agggcttgag atggcactgt atagaacgcg gaaaaaccga
     3481 aaaaatgtat tgtacaacac acaaccgtct gagcctgaag cgcaggaaag tgaaaaagca
     3541 gagagtcccg gcattattga taaagaattc ttcaataaaa tcggtgagga tttcaaccct
     3601 aagaagttca acaaaaaatt ctgaggtgat ttatgaaagt agcggtaatt aattacagtg
     3661 gcagtgttgg taaaacctta atttcatctt acctgttagc cccgcgcctg actggtgcaa
     3721 agttctatgc ggtagagact ataaaccagt ctgcttccga tctgggtatt gaaaatgtga
     3781 ccagttttaa aggtgacgac ttctcacgtt tgattgaggg gtaatgactc caacttactg
     3841 atagtgtttt atgttcagat aatgtccaat gactttgtca tgcagttctc ccttcaggcg
     3901 tgattcataa agcggccagt catccgtcat ccataccacg acctcaaagg ccgacagcag
     3961 gcccggaaga cgctccagca tggccaacgt gcgttcaccg aatacgtgcg ccacaaccgt
     4021 cctccgtatc ctgtcatacg cgtaaaacaa ccagcgctgg cgtgatttag cgccgacgta
     4081 accccactgt tcgtccattt ccgcgcaaac aatgacgtca ctgcccggtt gtatacgtga
     4141 gtttaccgac tgcggcctga gttttttaag tgtcgtaaaa tcgtgttgag gccaatgccc
     4201 ataatgcgtg cactggcgcg gcatccgacg ccattcatgg ccatatcaat aattttctgg
     4261 tgtgtaccgg gctgagaggt ggtgtaagtg aactgtagct gccatgtttt acggcagtga
     4321 gagcagagat agcgctgatg tccggcagta cttttaccgt tacgcaccac gccttcagta
     4381 gctgagcagg agggacaact gatggagatg gaagccacgg gagcacctca aaaacaccat
     4441 catacactaa atcagcaagt tggtagcatt acccagaact ggacagaata ggctgtatgt
     4501 ctaacttctg gccacagata taatcgagcc agcagtgctc gccgcagccg agcgacaggg
     4561 cgaagccccg agtgagcgag gaagcaccat ggaacagtac tcataaattc tgcatacgct
     4621 caatgcctgc aaaatcacct cccctagggg ttatccactt atccacgggg atatttttat
     4681 aagatctttt taaatagttg ttagatcttt atttttagaa tgcccacagg cctttatcca
     4741 tgcgggttcc agagagggat ctgtgacaaa acgccctttc agtgtgacaa atcaccctca
     4801 aatagccgcc ctttctgtga caagttgccc ttaaccctgt gacaaattgc cctcaggaag
     4861 cgttgctttt cacaaagtta tccatccctg ttgactctgt tttatgaagt gtgaaaatct
     4921 taaagtctgt cacacttcac atggacctgt catggcggaa atagcggtta taaaccataa
     4981 aaaacgtaaa aatagcccgc ggattgtcca gtcaaacgag ctgactgagg cggcatatag
     5041 tctctccagg gatcaaaagc gtatgctgta tctgttcgtt gaccagatca gaaaatccga
     5101 cggctccctg caggaacatg acggcatctg cgaaattcac gttgctaaat acgctgaaac
     5161 attcgggctg acctccgctg aagccagtaa ggatatacga caggctttaa aaggttttgc
     5221 gggtaaggaa gtggttttct atcgccctga agaggatgcc ggcgatgaaa aagggtatga
     5281 atcctttccc tggtttatta aacgtgcgca cagcccatcc agagggcttt acagcgtaca
     5341 tatcaaccct tatctgattc ccttcttcat cgggttacag aaccggttta cgcagttccg
     5401 gctcagtgaa acaaaagaga ttaccaatcc gtacgccatg cgtttatacg aatctctgtg
     5461 ccagtaccgt aaacctgatg gctcaggtgt cgtgtccctg aaaatcgact ggatcatgga
     5521 acgctaccag ctacctcaaa gttaccagcg tatgccggac tttcgccgcc gtttcctgca
     5581 ggcaagtgtt gacgagatca acagccggac accaatgcgc ctttcttaca tcgagaaaaa
     5641 gaaaggccgc cagacgacgc atatcgtatt ttccttccgt gatataacct ccatgacgat
     5701 tgaatagttg agggctatct gtcacagatt taagggtggt tcgtcacatt tgatctggaa
     5761 agttgagggt gatttgtcac agttttgctg ttccctccct ggcatcctgc gcttactcat
     5821 agtttttttg gctgtaaccg gtagtggagc cagaattgag ggcaatttgt caccctatcc
     5881 tgagggtagt ttgtcacact agattttctc cctcttcccg ggtaatggtg ccaacttact
     5941 gatttagtgt atgatggtgt ttttgaggtg ctcccgtggc ttccatctcc atcagttgtc
     6001 cctcctgctc agctactgaa ggcgtggtgc gtaacggtaa aagtactgcc ggacatcagc
     6061 gctatctctg ctctcactgc cgtaaaacat ggcagctaca gttcacttac accgcctctc
     6121 aggccgcagt cggtaaactc acgcatacaa ccgggcagtg acgtcattgt ttgcgcggaa
     6181 atggacgaac agtggggtta cgtcggcgct aaatcacgcc agcgctggtt gttttacgcg
     6241 tatgacagga tacggaggac ggttgtggca cacgtcttcg gtgaacgtac tatggccacg
     6301 ctggagcatc ttctgagcct gccgtcggac tttcagggcg cgtggttcct tttaaacacc
     6361 agctctgtat ctcttttaaa gatcctttaa taaattctgt aaacccataa tctgttcatc
     6421 gcctgcattg tggaccggct cgggagaatg cccgcccttg cagctaccag acggtcgcac
     6481 cggttcggca acaccaaaga gagctcccat cgcttcgcga cgggccccga ccggagaatt
     6541 aaattagtta cagcattcat aatgatattc atcataaaac cggcgccggt ttgccggccc
     6601 ggtgcccctc cccaccactg aaaagcgccg ccgcccccgc ccaaagggcg ggaacaacat
     6661 cgcttttaat tatgaatgtt gtaactatac catcatcgct gtcagtcctc tggctggaag
     6721 tccccagtac acgctcgtaa gcggccctga cggcccgcta acgcggagat acgccccgac
     6781 ttcgggtaaa ccctcgtcgg gaccactccg accgcgcaca gaagctctat catggctgaa
     6841 aacgggtatg gtctggcagg gccggggatg gataaggtga aatctatcaa tcagtaccgg
     6901 ctgacgccgg gcttcggcgg ttttaccccg gtatcatatg caacaatgga gtgccgcctt
     6961 ccatgccgct gacgcggcat atcctggtga cgatatctga atcgttatat actatgtata
     7021 tacgtagtaa tgacgaggtg ataaatggca caggttaata tgagtttaag aatcgacgct
     7081 gaactgaagg atgcttttat ggccgctgca aaaagcatgg accgtaatgg ctctcagtta
     7141 atccgggatt ttatgcgcca gaccgttgaa cggcagcata atacctggtt ccgtgaccag
     7201 gttgcggcag gacgtcagca actcaagcgc ggcgatgtgc ttccccatga catggtcgaa
     7261 tcttctgctg ctgcatggcg ggatgaaatg agcaggaagg ttgccgataa atgatggaga
     7321 tattctggac catgctggcc agccaggaca ggaagcgcat tcgtgagtac attgcggagc
     7381 agaacctgat ggtcgccatt gaactggacg aacggattgg ttattcagcc agcagcctgg
     7441 ccgggcagcc gtataaaggc cgcaacggtc gtgtggaagg tgcccgggaa ctggttattc
     7501 acccgcattt tgttctggtt tatgaggtcg atagcccgtg gggaaaagtg tatatcctgc
     7561 gtgtattgca tactgcacag aagtggccat agagggggag cccgcagaat tcggaaaaaa
     7621 tcgtacgcta aggttttccg ggcatccgta agggccgaaa cttcccgtct tccagtctgc
     7681 ggctctgccg ccagacgtaa tcgccggtta ggttgatgtg ctcccagccc agcggcgaca
     7741 ggaattgcag cagctcgccg tccaccggct tgccggcctc gaccaacccc tgggtggcgc
     7801 gttccaggta caccgtgttc cacagcacga tagccgccgt caccaggttg aggccgctgg
     7861 cccggtagcg ctgctgctcg aagctccgat ccctgatttc cccaaggcgg ttgaagaaca
     7921 ccgccctggc cagcgagttg cgcgcctcac ctttgttcag gccggcatgc acgcggcggc
     7981 gcagttcaac actttgcagc cagtccagga tgaacagcgt gcgctcgatc cggcccagct
     8041 cgcgcagggc cacggccagt ccgttctggc gcgggtagct gccgagcttg cgcagcatca
     8101 gcgaggcggt gacggtgccc tgcttgatcg agctggccag gcgcaggatg tcgtcccagt
     8161 gggcacgcac gtgcttgatg ttcagggtgc cgccgatcag cgggcgcaac gtcgggtagg
     8221 cttgcacgcc ctgcggcacg tacagcttgg tttcgccgag gtcgcggatg cgcggcgcga
     8281 agcggaagcc tagcaggtgc atcagggcaa agacgtgatc ggtgaagccg gccgtgtcgg
     8341 tgtagtgctc ctcgatccgc aggtcggact cgtggtacag caggccgtcg agcacatagg
     8401 tggaatcgcg gacgccgaca ttcaccacgc gggtgctgaa cggcgcgtac tggtcggaga
     8461 tatgggtata gaacagccgt cccggctcgc taccgtactt cgggttgacg tgcccggtgc
     8521 tctcgccccg gccacccgcg cggaagcgct ggccatcgga ggatgaggtc gtgccgtcgc
     8581 cccagtgggc ggcaaaggcg tggcgatact ggtggttgac cagctcggcc aaggccgccg
     8641 aataggtttc gtcgcggatg tgccaggctt gcagccagga cagcttggcg taggtcaggc
     8701 cggggctcga ctcggccatc ttggtcagcc cgaggttgat cgcatcaccg aggattgcgg
     8761 acagcagcaa cgtcctgtct ttggcctcgg ccccgtcctt caagtgggtg aagtggcggc
     8821 tgaagcccgt ccagtcgtcc acgtccatca gcagttcggt gatcttgatg cgcggcagta
     8881 actggctggt ttggtcgatc agcgcctgcg cccgatccgg caccgccgca tccagcgggg
     8941 tgattttcag ccctgactcg gtgaggatgg catcgggcag ctcgttgtcc ttggccaggc
     9001 gggtgacggt ggccaactgc tcgtccagca gctgcaaacg ctcttccagg tactggtcgc
     9061 tgttcgggtt gatcgccagg ggcagggcct gctcgcgctt gagtgcggcg aacttctcgg
     9121 ccggcagcag gtagtcgtcg aagtcgcgga actgccgcga gcccttgacc cagatgtcgc
     9181 cggagcgcag ggcgttcttc agctcggaca gggcgcagat ttcgtagaat ttccggtcga
     9241 ggccttccgg ggtgatcacc agcggcttcc agcgcggctt gatgaaggcc gtgggtgcat
     9301 cggccggcac cttgcgcagg ttgtcggcgt tcatctcacg cagggtctgc acggctgcca
     9361 gcacgccttg cgcggccggc ccgtgctgtt ccccaacttt tcgctcggcg aagagtatga
     9421 acatgcgccg ccggcgacga atcgccaaat ctcaccgtat ctcccgagcg gacgatttcg
     9481 caccggtctg cccgtcgaag ggcttgcgat cgaacggggc gaccttttct atgcatgtcc
     9541 gcgagccagc gtcttttatg gcacggcgct cgacgccgac cttcggacgc gcggcgtaag
     9601 cacgcttgtc atggccggga taagcaccac cggcgttgtt ctttcaagcg tcgcctgggc
     9661 tagtgatgcg gactacgacg tgcgtttggt ccaggactgc tgctacgacc cggatcggga
     9721 tgcccacgaa gctctgttgc gttccgggtt cggcggacgt gtacaggtcg tgtaattttc
     9781 gggcctcgca tgatcgcggc catagccgca ggtggattgg tgcgaggcag ggccagtcca
     9841 agtcagggtg cggtcatcgc ggcgcctgca actctcaaaa acccatcgcc gtagcggagg
     9901 tcttgtaatc gcatgtcatt acgcacgccc gatttattgt tcacagcgat agcacctgcc
     9961 atttggggca gcacctacat tgtcaccacc caatacctgc cgaacttctc accgatgacg
    10021 gtcgcgatgc tgcgggcgtt gccggcgggt ttattgctcg tgatgatcgt ccgacagatt
    10081 ccaacgggaa tctggtggat gcgcatcttc atcctcggcg cacttaatat ttcgctattc
    10141 tggagcttgt tgtttatttc ggtctaccgc ctgccgggcg gggtcgcggc gacggtaggc
    10201 gctgtgcagc cgctgatggt cgtgttcatc tctgccgctc tgctaggtag cccgatacga
    10261 ttgatggcgg tcctgggggc tatttgcgga actgcgggcg tggcgctgtt ggtgttgaca
    10321 ccaaacgcag cgctagatcc tgtcggcgtc gcagcgggcc tggcgggggc ggtttccatg
    10381 gcgttcggaa ccgtgctgac ccgcaagtgg caacctcccg tgcctctgct cacctttacc
    10441 gcctggcaac tggcggccgg aggacttctg ctcgttccag tagctttagt gtttgatccg
    10501 ccaatcccga tgcctacagg aaccaatgtt ctcggcctgg cgtggctcgg cctgatcgga
    10561 gcgggtttaa cctacttcct ttggttccgg gggatctcgc gactcgaacc tacagttgtt
    10621 tccttactgg gctttctcag cccggggacc gccgtgttgc taggatggtt gttcttggat
    10681 cagacgctga gtgcgcttca aatcatcggc gtcctgctcg tgatcgggag tatctggctg
    10741 ggccaacgtt ccaaccgcac tcctagggcg cgtatagctt gccggaagtc gccttgaccc
    10801 gcatggcata ggcctatcgt ttccacgatc agcgatcggc tcgttgccct gcgccgctcc
    10861 aaagcccgcg acgcagcgcc ggcaggcaga gcaagtagag ggcagcgcct gcaatccatg
    10921 cccacccgtt ccacgttgtt atagaagccg catagatcgc cgtgaagagg aggggtccga
    10981 cgatcgaggt caggctggtg agcgccgcca gtgagccttg cagctgcccc tgacgttcct
    11041 catccacctg cctggacaac attgcttgca gcgccggcat tccgatgcca cccgaagcaa
    11101 gcaggaccat gatcgggaac gccatccatc cccgtgtcgc gaaggcaagc aggatgtagc
    11161 ctgtgccgtc ggcaatcatt ccgagcatga gtgcccgcct ttcgccgagc cgggcggcta
    11221 cagggccggt gatcattgcc tgggcgagtg aatgcagaat gccaaatgcg gcaagcgaaa
    11281 tgccgatcgt ggtcgcgtcc cagtgaaagc gatcctcgcc gaaaatgacc caaagcgcgg
    11341 ccggcacctg tccgacaagt tgcatgatga agaagaccgc catcagggcg gcgacgacgg
    11401 tcatgccccg ggcccaccgg aacgaagcga gcgggttgag agcctcccgg cgtaacggcc
    11461 ggcgttcgcc tttgtgcgac tccggcaaaa ggaaacagcc cgtcaggaaa ttgaggccgt
    11521 tcaaggctgc cgcggcgaag aacggagcgt ggggggagaa accgcccatc agcccaccga
    11581 gcacaggtcc cgcgaccatc ccgaacccga aacaggcgct catgaagccg aagtgccgcg
    11641 cgcgctcatc gccatcagtg atatcggcaa tataagcgcc ggctaccgcc ccagtcgccc
    11701 cggtgatgcc ggccacgatc cgcccgatat agagaaccca aaggaaaggc gtcgtcgcca
    11761 tgatggcgta gtcgacagca gcgccggcca gcgagacgag caagaccggc cgccgcccga
    11821 aacgatccga cagcgcgccc agcacaggtg cgcaggcaaa ttgcatcaac gcatacagcg
    11881 ccagcagaat gccatagtgg gcggtgacgt cgttcgagtg aaccagatcg cgcaggaggc
    11941 ccggcagcac cggcataatc aggccgatgc cgacagcgtc gagcgcgaca gtgctcagaa
    12001 ttacgatcag gggtctgttg ggtttcacgt ctggcctccg gaccagcctc cgctggtccg
    12061 attgaacgcg cggattcttt atcactgata agttggtgga catattatgt ttatcagtga
    12121 taaagtgtca agcatgacaa agttgcagcc gaatacagtg atccgtgccg ccctggacct
    12181 gttgaacgag gtcggcgtag acggtctgac gacacgcaaa ctggcggaac ggttgggggt
    12241 tcagcagccg gcgctttact ggcacttcag gaacaagcgg gcgctgctcg acgcactggc
    12301 cgaagccatg ctggcggaga atcatacgca ttcggtgccg agagccgacg acgactggcg
    12361 ctcatttctg atcgggaatg cccgcagctt caggcaggcg ctgctcgcct accgcgatgg
    12421 cgcgcgcatc catgccggca cgcgaccggg cgcaccgcag atggaaacgg ccgacgcgca
    12481 gcttcgcttc ctctgcgagg cgggtttttc ggccggggac gccgtcaatg cgctgatgac
    12541 aatcagctac ttcactgttg gggccgtgct tgaggagcag gccggcgaca gcgatgccgg
    12601 cgagcgcggc ggcaccgttg aacaggctcc gctctcgccg ctgttgcggg ccgcgataga
    12661 cgccttcgac gaagccggtc cggacgcaga gttcgagcag ggactcgcgg tgattgtcga
    12721 tggattggcg aaaaggaggc tcgttgtcag gaacgttgaa ggaccgagaa agggtgacga
    12781 ttgatcagga ccgctgccgg agcgcaaccc actcactaca gcagagccat gtagacaaca
    12841 tcccctcccc ctttccaccg cgtcagacgc ccgtagcagc ccgctacggg ctttttcatg
    12901 ccctgcccta gcgtccaagc ctcacggccg cgctcggcct ctctggcggc cttctggcgc
    12961 tcctgctgcg gcgtccgctc gtgggccgtg gcgcgggtcc gcgcgccggc ctcgtgcgcc
    13021 tggcgctcgc gggcgaggtc cagggcggcc gtcttcacgt tctgccttgc gcagatgaga
    13081 taggggagcc cgcagaattc ggaaaaaatc gtacgctaag gttttccggg catccgtaag
    13141 ggccgaaact tcccgtcttc cagtctgcgg ctctgccgcc agacgtaatc gccggttagg
    13201 ttgatgtgct cccagcccag cggcgacagg aattgcagca gctcgccgtc caccggcttg
    13261 ccggcctcga ccaacccctg ggtggcgcgt tccaggtaca ccgtgttcca cagcacgata
    13321 gccgccgtca ccaggttgag gccgctggcc cggtagcgct gctgctcgaa gctccgatcc
    13381 ctgatttccc caaggcggtt gaagaacacc gccctggcca gcgagttgcg cgcctcacct
    13441 ttgttcaggc cggcatgcac gcggcggcgc agttcaacac tttgcagcca gtccaggatg
    13501 aacagcgtgc gctcgatccg gcccagctcg cgcagggcca cggccagtcc gttctggcgc
    13561 gggtagctgc cgagcttgcg cagcatcagc gaggcggtga cggtgccctg cttgatcgag
    13621 ctggccaggc gcaggatgtc gtcccagtgg gcacgcacgt gcttgatgtt cagggtgccg
    13681 ccgatcagcg ggcgcaacgt cgggtaggct tgcacgccct gcggcacgta cagcttggtt
    13741 tcgccgaggt cgcggatgcg cggcgcgaag cggaagccta gcaggtgcat cagggcaaag
    13801 acgtgatcgg tgaagccggc cgtgtcggtg tagtgctcct cgatccgcag gtcggactcg
    13861 tggtacagca ggccgtcgag cacataggtg gaatcgcgga cgccgacatt caccacgcgg
    13921 gtgctgaacg gcgcgtactg gtcggagata tgggtataga acagccgtcc cggctcgcta
    13981 ccgtacttcg ggttgacgtg cccggtgctc tcgccccggc cacccgcgcg gaagcgctgg
    14041 ccatcggagg atgaggtcgt gccgtcgccc cagtgggcgg caaaggcgtg gcgatactgg
    14101 tggttgacca gctcggccaa ggccgccgaa taggtttcgt cgcggatgtg ccaggcttgc
    14161 agccaggaca gcttggcgta ggtcaggccg gggctcgact cggccatctt ggtcagcccg
    14221 aggttgatcg catcaccgag gattgcggac agcagcaacg tcctgtcttt ggcctcggcc
    14281 ccgtccttca agtgggtgaa gtggcggctg aagcccgtcc agtcgtccac gtccatcagc
    14341 agttcggtga tcttgatgcg cggcagtaac tggctggttt ggtcgatcag cgcctgcgcc
    14401 cgatccggca ccgccgcatc cagcggggtg attttcagcc ctgactcggt gaggatggca
    14461 tcgggcagct cgttgtcctt ggccaggcgg gtgacggtgg ccaactgctc gtccagcagc
    14521 tgcaaacgct cttccaggta ctggtcgctg ttcgggttga tcgccagggg cagggcctgc
    14581 tcgcgcttga gtgcggcgaa cttctcggcc ggcagcaggt agtcgtcgaa gtcgcggaac
    14641 tgccgcgagc ccttgaccca gatgtcgccg gagcgcaggg cgttcttcag ctcggacagg
    14701 gcgcagattt cgtagaattt ccggtcgagg ccttccgggg tgatcaccag cggcttccag
    14761 cgcggcttga tgaaggccgt gggtgcatcg gccggcacct tgcgcaggtt gtcggcgttc
    14821 atctcacgca gggtctgcac ggctgccagc acgccttgcg cggccggcgc ggcgcgcagt
    14881 tccagcacct ccagcaaggc cggcgtgtaa cggcgcaggg tggcgaagtt ctcgccgacc
    14941 aggtgcaggt ggtcgaagcc ttccggccgg gccagcagct cggcctcgct gacgctctcg
    15001 gtgaactcgt cccagggaat caccgcctcg atggcggcat aggggtcgct gccgctttcc
    15061 ttcgcttcca gcagcgcctg gccgatcctg gagtacaggc gcaccttgtc gttgatcgcc
    15121 ttgccctgct tctggaactg ctgctgatgc ttgtgcttcg cgccgctgaa cagcttgacc
    15181 aggatgcggt catgcagatc gaccagctca tcgatcacgg tcgcggtgct ctccagcacc
    15241 acggcggcca gggtcgcgta gcggcgctgc ggctcgaact taccgaggtc tttgggcgtc
    15301 atctgcccac cctcgcgggc cagcttgagc aggcggttct ggtggatgtg ccggcccagg
    15361 ccttcgggca agtccaccaa ctgaaatgtc ttcagccgct cgatgtgttc cagcatgtgc
    15421 cgagagttgg gtttcagcgg tgcctggcgc agccaggtca accaggtgat gctgctgccg
    15481 gccttgagct tcaacagctc gtccagcttg gcccgatgcg agtccgtgag tggttcgacc
    15541 agggcgcggt agacccgccg attggctcgc gcaatggctt ccgagcaggc ccggtcaatc
    15601 acgctcagcg ccggcaggat gcgtcgtttc tgccgtaggc tctccagggc ctgaccggcc
    15661 agcagcaagc ctttgtcggt ctgctgggcc agctcggtta gctcgcgcac cagggcgcgg
    15721 aagtcggaca ggccgaacgg ggccagttgc aggtaggtgc gcagttcctg ggcatgctcg
    15781 cgacgggtca cgtcgcgctc gccgtacttt gcccagctcg ccggctcggc ctggacttgc
    15841 ttcgccaccc acaggatgac cggctcgggc agctcgctgt cggttcccag cgcgtaaccg
    15901 gggtagcgca gcaggcagag ctgcacggcg aagccgaggc ggttggcgtc gccgcgtcgc
    15961 tggcggatca gcgacaggtc ggagtcgttg aaggtgtagt agcggatcag gtcatcctgg
    16021 ctttccggca gcgcaagcag ggtgtcccgc tccgtggccg agaggatcaa gcgacgcggc
    16081 atgtgtcagt cgtccgtgcg gaggtactgg tagagggttt cccggctgat gttgaactcg
    16141 cgggcaagct gcgccttggg ctcgccggcc gttgctcgct gccgcagggt agcagcctgc
    16201 tcatcggaca gggctttctt gcggccccgg tacgcgccac gctgcttggc caaggcgatg
    16261 ccctcacgct gccgctcgcg gatcagggcg cgctcgaact cagcgaaggc ccccatcacc
    16321 gacagcatca ggttggccat cggcgagtcc tcgccagtga acaccaggcc ctccttcagg
    16381 aactcgatgc gcacgccgcg ctgagtcagc ttctgtacca agcgacgcag gtcatcgagg
    16441 ttgcgggcca gccgatccat gctgtgcacc accactgtat cgccttcgcg gacgaagctc
    16501 agcagcgctt cgagctgggg gcgctgggtg tccttgcccg atgccttgtc ggtgaacacc
    16561 ttgctcacct gggtttgttc cagctggcgt tccgggttct ggtcaaagct gctgacccgg
    16621 acgtagccga tgcggtgccc ctgcacgatg tctccttggt tgaaggcggc ttaagtgcac
    16681 tttctgttcc gttgtgcctc aaagcccatt tctgtcaggc tgaaatctat aaccttcgcg
    16741 ggcatgtgtc aaaaaatggg aaagcagact ctattctgac gaagcggcgc ggccctgcct
    16801 gacatcaagt tagggtatgc ctcaacctgg cggcggcgaa tcacaagcgt ccggtttgac
    16861 gctggtttcg gtcgcagtgc tggcccgcgc ctggaagcgc tgatagcact ccagcccgca
    16921 gaaatgctcc acgtactcgg ccccttccgg cgtgaaggcg gcatcgagcg ggatttcctt
    16981 gcagcacacg cagcaactgg tgctcggttc attggcgttc atggtggtgt tcctccattg
    17041 gttgacgaag ccgacgaagg ccgccgccgg catcggcctg gcgaacagga aaccctgcac
    17101 cgtgtcgcaa cccgcctgcc gcaaccacgc aaggcagtcg ggtgtttcca caccctcggc
    17161 taccacctcc attgtcgttt tcagaagacg gctgcactga acgtcagaag ccgactgcac
    17221 tatagcagcg gaggggttgg atccatcagg caacgacggg ctgctgccgg ccatcagcgg
    17281 acgcagggag gactttccgc aaccggccgt tcgatgcggc accgatggcc ttcgcgcagg
    17341 ggtagtgaat ccgccaggat tgacttgcgc tgccctacct ctcactagtg aggggcggca
    17401 gcgcatcaag cggtgagcgc actccggcac cgccaacttt cagcacatgc gtgtaaatca
    17461 tcgtcgtaga gacgtcggaa tggccgagca gatcctgcac ggttcgaatg tcgtaaccgc
    17521 tgcggagcaa ggccgtcgcg aacgagtggc ggagggtgtg cggtgtggcg ggcttcgtga
    17581 tgcctgcttg ttctacggca cgtttgaagg cgcgctgaaa ggtctggtca tacatgtgat
    17641 ggcgacgcac gacaccgctc cgtggatcgg tcgaatgcgt gtgctgcgca aaaacccaga
    17701 accacggcca ggaatgcccg gcgcgcggat acttccgctc aagggcgtcg ggaagcgcaa
    17761 cgccgctgcg gccctcggcc tggtccttca gccaccatgc ccgtgcacgc gacagctgct
    17821 cgcgcaggct gggtgccaag ctctcgggta acatcaaggc ccgatccttg gagcccttgc
    17881 cctcccgcac gatgatcgtg ccgtgatcga aatccagatc cttgacccgc agttgcaaac
    17941 cctcactgat ccgcatgccc gttccataca gaagctgggc gaacaaacga tgctcgcctt
    18001 ccagaaaacc gaggatgcga accacttcat ccggggtcag caccaccggc aagcgccgcg
    18061 acggccgagg tcttccgatc tcctgaagcc agggcagatc cgtgcacagc accttgccgt
    18121 agaagaacag caaggccgcc aatgcctgac gatgcgtgga gaccgaaacc ttgcgctcgt
    18181 tcgccagcca ggacagaaat gcctcgactt cgctgctgcc caaggttgcc gggtgacgca
    18241 caccgtggaa acggatgaag gcacgaaccc agtggacata agcctgttcg gttggtaagc
    18301 tgtaatgcaa gtagcgtatg cgctcacgca actggtccag aaccttgacc gaacgcagcg
    18361 gtggtaacgg cgcagtggcg gttttcatgg cttgttatga ctgttttttt gtacagtcta
    18421 tgcctcgggc atccaagcag caagcgcgtt acgccgtggg tcgatgtttg atgttatgga
    18481 gcagcaacga tgttacgcag cagggcagtc gccctaaaac aaagttagcc atatgaactc
    18541 ggaatcagta cgcatttatc tcgttgctgc gatgggagcc aatcgggtta ttggcaatgg
    18601 tcctaatatc ccctggaaaa ttccgggtga gcagaagatt tttcgcagac tcactgaggg
    18661 aaaagtcgtt gtcatggggc gaaagacctt tgagtctatc ggcaagcctc taccgaaccg
    18721 tcacacattg gtaatctcac gccaagctaa ctaccgcgcc actggctgcg tagttgtttc
    18781 aacgctgtcg cacgctatcg ctttggcatc cgaactcggc aatgaactct acgtcgcggg
    18841 cggagctgag atatacactc tggcactacc tcacgcccac ggcgtgtttc tatctgaggt
    18901 acatcaaacc ttcgagggtg acgccttctt cccaatgctc aacgaaacag aattcgagct
    18961 tgtctcaacc gaaaccattc aagctgtaat tccgtacacc cactccgttt atgcgcgtcg
    19021 aaacggctaa ccattccgtc aacgggacgc caaaatgctg cgcattttgg ttccctccgc
    19081 tgcgctccgg ctctcgttac gtccaacgtt agcaccactg aaacccagct ttatttagct
    19141 catgtttatt caaacggcat ttagcttttc aggcgttatt cagtgcctgt tttgcctttt
    19201 ttccgggctt cgcctgcatg ggctgcgcag gttttcagtc tttttggcct ctagcccttg
    19261 cgtagcaagc gcaagcagct atcgtttttg cagtgctgtg ccgcctcggt ggcgcagcgt
    19321 tttttcacgg ttagcgcccg tcgccaaatt caagttatcc gttttggctt ctggttctaa
    19381 catttcggtc aagccgaccc gcattctgcg gtcggcttac ctcgcccgtt agacatcatg
    19441 agggaagcgg tgaccatcga aatttcgaac caactatcag aggtgctaag cgtcattgag
    19501 cgccatctgg aatcaacgtt gctggccgtg catttgtacg gctccgcagt ggatggcggc
    19561 ctgaagccat acagcgatat tgatttgttg gttactgtgg ccgtaaagct tgatgaaacg
    19621 acgcggcgag cattgctcaa tgatcttatg gaggcttcgg ctttccctgg cgagagcgag
    19681 acgctccgcg ctatagaagt cacccttgtc gtgcatgacg acatcatccc gtggcgttat
    19741 ccggctaagc gcgagctgca atttggagaa tggcagcgca atgacattct tgcgggtatc
    19801 ttcgagccag ccatgatcga cattgatcta gctatcctgc ttacaaaagc aagagaacat
    19861 agcgttgcct tggtaggtcc ggcagcggag gaattctttg acccggttcc tgaacaggat
    19921 ctattcgagg cgctgaggga aaccttgaag ctatggaact cgcagcccga ctgggccggc
    19981 gatgagcgaa atgtagtgct tacgttgtcc cgcatttggt acagcgcaat aaccggcaaa
    20041 atcgcgccga aggatgtcgc tgccgactgg gcaataaaac gcctacctgc ccagtatcag
    20101 cccgtcttac ttgaagctaa gcaagcttat ctgggacaaa aagaagatca cttggcctca
    20161 cgcgcagatc acttggaaga atttattcgc tttgtgaaag gcgagatcat caagtcagtt
    20221 ggtaaatgat gtctaacaat tcgttcaagc cgaccgcgct acgcgcggcg gcttaactcc
    20281 ggcgttgggc gcacaataag gctccttgca gagttgcttg aaagttgtta cgattcaaat
    20341 tcaatcatga gatagtcagc agatgagcac ttccaagaac gcagacaagt aagccgcagc
    20401 aaccttcatt tttcggttgt tgcggcgttc tcatgaatcc ttttgctcta cgggagcgcc
    20461 gccaaatcct ttgttcaagg agatggtttc gtgagctcaa aaaactttag ttggcggtac
    20521 tcccttgccg ccacggtgtt gttgttatca ccgttcgatt tattggcatc actcggcatg
    20581 gacatgtact tgccagcagt gccgtttatg ccaaacgcgc ttggtacgac agcgagcaca
    20641 attcagctta cgctgacaac gtacttggtc atgattggtg ccggtcagct cttgtttgga
    20701 ccgctatcgg accgactggg gcgccgcccc gttctactgg gaggtggcct cgcctacgtt
    20761 gtggcgtcaa tgggcctcgc tcttacgtca tcggctgaag tctttctggg gcttcggatt
    20821 cttcaggctt gtggtgcctc ggcgtgcctt gtttccacat ttgcaacagt acgtgacatt
    20881 tacgcaggtc gcgaggaaag taatgtcatt tacggcatac tcggatccat gctggccatg
    20941 gtcccggcgg taggcccatt gctcggagcg ctcgtcgaca tgtggcttgg gtggcgggct
    21001 atctttgcgt ttctaggttt gggcatgatc gctgcatctg cagcagcgtg gcgattctgg
    21061 cctgaaaccc gggtgcaacg agttgcgggc ttgcaatggt cgcagctgct actccccgtt
    21121 aagtgcctga acttctggtt gtacacgttg tgttacgccg ctggaatggg tagcttcttc
    21181 gtctttttct ccattgcgcc cggactaatg atgggcaggc aaggtgtgtc tcagcttggc
    21241 ttcagcctgc tgttcgccac agtggcaatt gccatggtgt ttacggctcg ttttatgggg
    21301 cgtgtgatac ccaagtgggg cagcccaagt gtcttgcgaa tgggaatggg atgcctgata
    21361 gctggagcag tattgcttgc catcaccgaa atatgggctt tgcagtccgt gttaggcttt
    21421 attgctccaa tgtggctagt gggtattggt gtcgccacag cggtatctgt ggcgcccaat
    21481 ggcgctcttc gaggattcga ccatgttgct ggaacggtca cggcagtcta cttctgcttg
    21541 ggcggtgtac tgctaggaag catcggaacg ttgatcattt cgctgttgcc gcgcaacacg
    21601 gcttggccgg ttgtcgtgta ctgtttgacc cttgcaacag tcgtgctcgg tctgtcttgt
    21661 gtttcccgag tgaagggctc tcgcggccag ggggagcatg atgtggtcgc gctacaaagt
    21721 gcggaaagta catcaaatcc caatcgttga gagaatgtgg caagctatcg cccaacaaat
    21781 cgctgcagcc gacccaaaac cgctacgcgg tttcggtcgg ctgagctcag gcgttaaaca
    21841 tcatgaggga agcggtgatc gccgaagtat cgactcaact atcagaggta gttggcgtca
    21901 tcgagcgcca tctcgaaccg acgttgctgg ccgtacattt gtacggctcc gcagtggatg
    21961 gcggcctgaa gccacacagt gatattgatt tgctggttac ggtgaccgta aggcttgatg
    22021 aaacaacgcg gcgagctttg atcaacgacc ttttggaaac ttcggcttcc cctggagaga
    22081 gcgagattct ccgcgctgta gaagtcacca ttgttgtgca cgacgacatc attccgtggc
    22141 gttatccagc taagcgcgaa ctgcaatttg gagaatggca gcgcaatgac attcttgcag
    22201 gtatcttcga gccagccacg atcgacattg atctggctat cttgctgaca aaagcaagag
    22261 aacatagcgt tgccttggta ggtccagcgg cggaggaact ctttgatccg gttcctgaac
    22321 aggatctatt tgaggcgcta aatgaaacct taacgctatg gaactcgccg cccgactggg
    22381 ctggcgatga gcgaaatgta gtgcttacgt tgtcccgcat ttggtacagc gcagtaaccg
    22441 gcaaaatcgc gccgaaggat gtcgctgccg actgggcaat ggagcgcctg ccggcccagt
    22501 atcagcccgt catacttgaa gctagacagg cttatcttgg acaagaagaa gatcgcttgg
    22561 cctcccgcgc agatcagttg gaagaatttg ttcactacgt gaaaggcgag atcaccaagg
    22621 tagtcggcaa ataatgtcta acaattcgtt caagccgacg ccgcttcgcg gcgcggctta
    22681 actcaagcgt tagatgccag atttggcgtt gcgtatgctc acagaaaatc gacagccgca
    22741 agactgtttt tggcaactca tagccaccac tatttatcct tcataccgta gaggagattg
    22801 cacgtgaaga actggctctt tctggctatt gcaatatttg gtgaggtcgt cgcaacttcc
    22861 gcactgaagt ccagccatgg attcaccaag ttagttcctt ctgttgtagt tgtggctggc
    22921 tacgggcttg cgttctattt cctctctctc gcactcaagt ccatcccggt cggcattgct
    22981 tatgctgttt gggctggcct cggcatcgta cttgtggcag ctatcgcttg gatcttccat
    23041 ggccagaaac tagacttgtg ggcgttcgtt ggcatgggac ttatcgttag tggcgtcgcc
    23101 gttctaaatc tgctatccaa ggtcagcgca cattgatcgg gctggcatct aacagttcat
    23161 tcaagccgac gccgcttcgc ggcgcggctt aattcaggtg ttagtcggac gcctacggcg
    23221 ccgaggaaaa aagaaaccaa accattcttg ctgccaaaga gaaaaacccc ttacggtggc
    23281 gtactgggaa agtgcgtatc tacgacgcct tgccggtctc aatgtcatgc cgtcctcttt
    23341 cgaaggctgc ttgatgcaaa cctctcaaaa atctggcata aactatcttg acatattccg
    23401 attgaacacc ttccgaatat cagcggctat cagcgggatc tcatcttttt tcgtgacgta
    23461 ggagtgggca ttctgctgca gatgaaactg gcagcgttgc cacagaattc cagggaagac
    23521 agcatcgatt gccgcgcgca gtcctgagtg gtcatcactg gtgatcattc gcaggccgtg
    23581 catccctcgt cgtacgagac cctcgagaaa ggaacgccag tttacctctg cctcactgtt
    23641 cgcgacttcg gcgtcaagaa tatgccgatt cccgctgtaa tcaacgccaa tagccactag
    23701 aagcgcctgc ttgaccacat gggaaccgac gcgaaccgat tcataggtcg catcaagtac
    23761 caagtattga atctgtccga caggctgcgc cttccaagac gtaatctctt catcgagctc
    23821 ctttgccagc ctgctgacct gggacgagct gacttcggtg ccacaaagaa tttcgacgat
    23881 atccgagacc ctgcgggtac ttactccttt gacatacatt tcggcgatgg cgagcttgag
    23941 agcacgctca ctgcgcatgc ctttctcgat gcagctggga taaaactcca tcccgcgaac
    24001 ttgtggtact ttcaagagga ctttcccggt cgcaagattg aatattggat tatttggatt
    24061 taccaacaaa cactactatt tagctacgaa aactcaagag aagtacacaa aaccttttgg
    24121 aagtgatgga agtttaagtc ctcttgatta tagtgtaggt attggaacag gtttagaatt
    24181 aggacatttc cagtttatgt ttggctatga ttaccctctt agtaacagtt cgaaagatcc
    24241 agacctaagt caagtacgcc aacacaactt cagagcaagt atagcatatt catttagaaa
    24301 gctaaaaaaa taaaactaac ctagggcttt ggatattttc aaggcatctg ataaagactt
    24361 aacatcatgg gtgcggagat aatctgcacc ttttttgtat gcatacattt ctgctgcaag
    24421 agttggtgct aaacgagatt tcacatcggt tccagttatt ttacctaaga atgatttccg
    24481 tgacactgca atcattactt gcaaattaaa agcttcttga atttcaggga aacgcttcaa
    24541 aacaagaata gatgtttctg gattagagcc taaaaagaag cccatacccg gatcaagaat
    24601 aattcgttca cgctttacac cagcctcaac taaagcagca attctttctt taaaaaattc
    24661 catcatggaa gtaaaaacct cttccggatt cgtttcaact ttagtagctg caccaattcg
    24721 ctgaacggag tgcatcaaca caagtttgca atctgacttt gccaagcctg aataaatctc
    24781 aggataagga aaaccttgaa tatcattaat aaaatcaacc ttttgttcta tgcaaaaact
    24841 ctgaacctca ggtttaaatg tatcaacaga aatagaaatg cctttttctt ttaaagcctt
    24901 aatgacaggt ttgagtcttt tgatttcttc cacaacgccc acttcagttg tatcaggatt
    24961 actggaagcg gctcccaaat caatcacatc tgctccatct tcaaccaaat gcagagcatg
    25021 ctcaattgcc ttatctgtat ctaaataaag tcctccatcg gaaaaactat cggtggttat
    25081 atttacgatt ccaaaaatct tgctcatatc attttgcttt gattacaaaa gtagcattta
    25141 tcttaattga ctaattatca cttacgcaaa ttgacacatt ttccctatct ttgcagccta
    25201 atttttttgt tttaattcat tatgaaaact gataggaact gtcatttcga gtttttcgcg
    25261 gttttgggtc aaaattcggt tttttccccg aactacgact gttttcgcac cccgaacaac
    25321 taatccaatc agaattttcc ggcaacgccg actccaagaa gtgtaattcc agtctatttc
    25381 tgccgtcaac ccctgattcg cgttaatgcg acaaagctca aacacataac tcccccacga
    25441 agccatataa actccgattt cgaggtgtta tcctgttccg cataaacttc gtttttgggt
    25501 attataccta caccaaagca agaagattat gggtccaaac ttcatttgta tattttgcaa
    25561 acaaatatct gcctgtcata tctgtcggag tgtggtgata ctcctttgca ttaaaaatgc
    25621 gctgataaaa ggtagttcag caaaaggcga aacgccaata aatatatcta taaccggttt
    25681 cgcccgttga ttgggtatcg ccgtgcttcc gatatgttca atggctacgg catgagaacc
    25741 gaaaaaatgg agcaatttta ttttctcttc ttcaaaattc tttgtccaat ccgggttata
    25801 ttccataatt tcaattttca tgatagtttc gtccttgcct caaaaaccat gtttggtatt
    25861 atactccata tctctccggt gcaggaatag ccttttctga tgcacggcta acagcttccc
    25921 attcttccca ggtagccatc cgtgctttta aggtatccat cgccaaatcg tataccatgc
    25981 tgccaaggat aagcctcaaa ggcggattat tgctggctac taatttcata agggcttccg
    26041 ctgccaagga aggatcacta tcgaccgaat cttcggaata ctgtttcgcc agctcatcgc
    26101 gcagtgtacc gtatgaatct aatggattgc tgtaactcat cgaagtgtat aaatctgtcc
    26161 aatatcctcc tggttccacc atagtgagtt tcactggcac tgttgcaaag ttagcgatga
    26221 ggcagccttt tgtcttattc aaaggcctta catttcaaaa actctgctta ccaggcgcat
    26281 ttcgcccagg ggatcaccat aataaaatgc tgaggcctgg cctttgcgta gtgcacgcat
    26341 cacctcaata cctttgatgg tggcgtaagc cgtcttcatg gatttaaatc ccagcgtggc
    26401 gttgattatc cgtttcagtt tgccatgatc gcattcaatc acgttgttcc ggtacttaat
    26461 ctgtcggtgt tcaacgtcag acgggcaccg gccttcgcgt ttgagcagag caagcgcgcg
    26521 accataggcg ggcgctttat ccgtgttgat gaatcgtggg atctgccact tcttcacgtt
    26581 gttgaggatt ttacccagaa accggtatgc agctttgctg ttacgacggg aggagagata
    26641 aaaatcgaca gtgcggcccc ggctgtcgac ggcccggtac agatacgccc agcggccatt
    26701 gaccttcacg taggtttcat ccatgtgcca cgggcaaaga tcggaagggt tacgccagta
    26761 ccagcgcagc cgtttttcca tttcaggcgc ataacgctga acccagcggt aaatcgtgga
    26821 gtgatcgaca ttcactccgc gttcagccag catctcctgc agctcacggt aactgatgcc
    26881 gtatttgcag taccagcgta cggcccacag aatgatgtca cgctgaaaat gccggccttt
    26941 gaatgggttc atgtgcagct ccatcagcaa aaggggatga taagtttatc accaccgact
    27001 atttgcaaca gtgccacgta aagggcgtga tttccgggga cttagcggcg gcagcttgct
    27061 gctgacgctt agggggatgt tcatcaactc tttcagcgac accagggaac ttaacacggt
    27121 agctgcaaag ccctaatccc gctcaccgcc acgcagctgc cgcacgtccc ccacgggggg
    27181 ggccgtactg cgcgttagcg gccgcacgcg gccggttacg ggggacactc cgccatacga
    27241 ccagctgagc tgcacaatcc acggataaca caagctacat acatgtcgat atgggaatcg
    27301 gcccaccttg ccgcgcgccg gtgctgtgtg gaaatcggcc caccttgccg cgcgccggtg
    27361 ctgtgtggaa atccgcccac cttaccgggc gccggtgccg tgtgggaatc agcccacctt
    27421 gccgggcgcc ggtgctgtgt ggaaatccgc ccaccttacc gggcgccggt gctgtgtgga
    27481 aatccgccca ctttgccggg cgccggtgcc gtgtgggaat cagcccacct tgccgggcgc
    27541 cggtgctgtg tgggaatcag cccaccttac cgggcgccgg tgccgtgtgg gaatcagccc
    27601 accttgccgg gcgccggtgc cgtgtgggaa tcagcccacc ttgccgggcg ccggtgccgt
    27661 gtggaaatcc gcccacctta ccgggcgccg gtgccgtgtg ggaatcagcc caccttgccg
    27721 cgcgccggtg ctgtgtggaa atccgcccac cttaccggac gccggtgccg tgtgggaatc
    27781 agcccacctt gccgcgcgcc ggtgctgtgt ggaaatccgc ccaccttacc gggcgccggt
    27841 gccgtgtggg aatcagccca ccttgccggg cgccggtgcc gtgtgggaat cagcccacct
    27901 taccgggcgc cggtgccgtg tggaaatccg cccaccttgc cgggcgccgg tgccgtgtgg
    27961 aaatcggccc accttgccgc gcgccggtgc tgtgtggaaa tccgcccacc ttaccggacg
    28021 ccggtgccgt gtgggaatca gcccaccttg ccgggcgccg gtgctgtgtg gaaatccgcc
    28081 caccttaccg ggcgccggtg ccgtgtggaa atccgcccac cttaccgggc gccggtgccg
    28141 tgtgggaatc agcccacctt gccgcgcgcc ggtgctgtgt ggaaatccgc ccaccttgcc
    28201 gggcgccggt gccgtgtggg aatcagccca ccttgccggg cgccggtgct gtgtggaaat
    28261 cggcccacct tgccgcgcac cggtgctgtg tggaaatcgg cccaccttgc cgggcgccgg
    28321 tgctgtgtgg aaatccgccc accttaccgg acgccggtgc cgtgtgggaa tcagcccacc
    28381 ttgccgggcg ccggtgccgt gtgggaatca gcccaccttg ccggttgccg gtgccgtgtg
    28441 gaaatccgcc catcttcatg acaaaaattt gtcaaatgac aggctcatgt gtgctgattt
    28501 atgtgtaagc gtgcagcaaa aaccgtattg acggggatgt gttattcagt cggcagtgct
    28561 acgcgccagg ggagcagttc gccgacccgg tttatcggcc agtcggctat gacgtcaagg
    28621 gcatagcgga ggtagctttc tggctccact ccgttcattt tgcacgtccc gatcaggctg
    28681 tacagcagcg ctccccgctc tcctccatga tccgaaccga agaacaggta gtttttgcgg
    28741 cccagactga ccatccgcaa cgcattttca gcgatgttat tgtccgcctc agcccagcca
    28801 tcatctgcat agtacgtcag cgccggccac tggttcaggg cgtatgcgaa cgctttcgcc
    28861 agttctgagt gtcgcgacag ggttttcatc ttttcacgca gccagctttc cagggatttc
    28921 agcagcggtt tcgttttcaa ctgacgttcg gcaaggcgct gctccgccgt cattcccctt
    28981 atctctgcct cgatggcgta cagttcgccg atccgtttca gcgctttctc cgtcagggct
    29041 gacggggtgc gaacgtgcac atcgtggatt ttacggcggg cgtgagccca acaggcggct
    29101 tccgttatcc ggccatcccg gtacagctcg ttgaacccgg cgtatgcatc cgcctgcagt
    29161 acaccactga accccgcaag atgggtctgc ggatggatgc cttttctgtc cgggctgtaa
    29221 gcgaaccaca ccgccggcgc cagcgttgac ccggcgttac ggtcgtcacg aacgtaggtc
    29281 cataaccgcc cggtcttcgt tttcttattg cctggcaaca gcaccgggac aggcgtgtca
    29341 tcagcatgga gcttaccgtc agtcagcaca tagtcctgaa gcgcttcttc cagcggtgac
    29401 agtagccggc agcatgcatc cacccagccc gacagcagtg aacgactcag ctccacgccc
    29461 tggcggccgt acatttcaga ctggcggtac agcggggtgt gctctgcata ctttgagatc
    29521 agcacgcagg ccagcagccc cggtcctgcg ataccccgct cgatgggccg tgaaggcgcg
    29581 ggggcctgca cgatggcatc gcactgagta caggcatgct tttcacgtac agtccggata
    29641 acccggaagg cgctgcgcat cagctccagc tgttcggcgg catcctcacc cagatagctc
    29701 agcgagcctc cacattccgg gcagcatgac gctgccggca gcagccgttt ttcatcgcgg
    29761 gggaggattc ggggaacggt ttgcgggtgc gggtttgacg cagcgggcgc tgcacggccg
    29821 ggtcgtcaac ccgaccggta agggtatcat tttctttctg aagtgccttc aggtcagctt
    29881 ccatctgtgc gatacgacgg gagatttttt cggagcagct gccgaagttc atccggcgca
    29941 gcttatccag ctgtgcctgc agatggtcta tttcgcgttc acgctcgttc agcttttcca
    30001 gcagggcacg gttcagcgcc tcctgttcgg caaggagacg tttcagtgca ttgatatcgt
    30061 caggaagtga gctgctcata ccgggtatat taccaggctc attcagcgtc gaccaggata
    30121 aagaggctta caacatagtc agggacgtaa gcagtctttt aggctgccgc cagtcgatac
    30181 cttcaaggag catcgccagc tgtgccggtg tgaggaacac tttgccatcc cgggctgacg
    30241 gccaggcgaa gcggccgcgc tccagccgtt tggtcagcag acacagtcca tcgccggtag
    30301 accagaggag ctttacctga ctgccattac gcccacggaa gataaaaacg tgacctgaca
    30361 tcggatcgtc tttcagcgtc gtctgcacct ttgccgccag gccgttgaag ccgtttctca
    30421 tatcggtgat gccagcgacc agccagatct ttgtccctga tggtaatggg atcaacgttt
    30481 gagctcccgg gtaatgactc caacttattg atagtgtttt atgttcagat aatgcccgat
    30541 gattttgtca tgcagctcca ccgattttga gaacgacagc gacttccgtc ccagccgtgc
    30601 caggtgctgc ctcagattca ggttatgccg ctcaattcgc tgcgtatatc gcttgctgat
    30661 tacgtgcagc tttcccttca ggcgggattc atacagcggc cagccatccg tcatccatat
    30721 caccacgtca aagggtgaca gcaggctcat aagacgctcc agcgtcgcca tagtgcgttc
    30781 accgaatacg tgcgcatcaa ccgtcttccg gagcctgtca tacgcgtaaa acagccagcg
    30841 ctggcgcgat ttagccccga cgtatcccca ctgttcgtcc atttccgcgc agacgatgac
    30901 gtcactgccc ggctgtatgc gcgaggttac cgactgcggc ctgagttttt taagtgacgt
    30961 aaaatcgtgt tgaggctaac gcccataatg cgtgcagttg cccggcatcc aacgccattc
    31021 atggccatat caataatttt ctggtgcgta ccgggttgag aagcggtgta agtgaactgc
    31081 agttgccatg ttttacggca gtgagagcag agatagcgct gatgtccggc ggtgcttttg
    31141 ccgttacgca ccaccccggt cagtagctga acaggaggga cagctgatag aaacagaagc
    31201 cactggagca cctcaaaaac accatcatac actaaatcag taagttggca gcatcacccg
    31261 ccagataata gtgttgcaaa taaaacagat tttttaaaca tataaaatac catcaatgaa
    31321 gtgattaaga agttatagag taacagagaa ttaataagat tcttttctct gagacgccag
    31381 aatatttgtt ctggcgtctg attttgagtt tatttgacta atgaaaatag atcattgagt
    31441 gattcgctca tcgacggatg agtaaatatc tgatcgcgta atatgctata aggcagcccg
    31501 gcatccatca ccattttcac tatattgatc atctcgtggg agtcaacaca cagcagtgat
    31561 gcccctaata tacgttgggt tttattatca acaatcgctt ttaatacccc acgggtatcg
    31621 ttcatcactc tggcacgcgg aattgcagct acaggcaatg tcaccacctg aatatcagca
    31681 ccactctctc tggcttgttc ttctgtcata ccaaccctgg acaggggcgg tgtcataaat
    31741 acggaataag gcacattttt ccgatcatca gtactacgtt tgccttcacc cagtaactca
    31801 tcacgtacaa tgcggtaatc atccagtgat atgtaagtaa attgcagccc gccggtaaca
    31861 tctcccatcg cccaaatatt gtctgcggtg gtatgtaatc gcttgtcaac gacaattgcc
    31921 ccgcgctcgt ttactgcgat accggcattt tctggatgta acgaagcggt agccggttga
    31981 cgaccggaag ctattaacag tgcatccacc gccagttggg cgtgctcgct atgcacttgc
    32041 acttgatttt catggtgact gattcgctcc acatgggcat tgaggataat atcgacgccc
    32101 tgatcgcgta aaatcgtcgc gatattatca gcaatatccc gatcttcccg aggcaaaaac
    32161 agcgaagctg actctaaaat ggttactttg ctgccaaaat tagcgaacat agaggcgaac
    32221 tcaacgccaa tatatccacc gcccaaaata cctaaatgcc caggcaattc ttttagatta
    32281 agtaatccgg tgctgtcata tacaccaggt gtggtggtaa ttccaggaat tggcggaacc
    32341 acggcttgtg caccggtatt aataaaaatt ttctcgccat gaatctccag atttccctca
    32401 ggccgatgaa cacgcaggct atgattattg ataaactccg cctggccgtc gatcacgtcg
    32461 atattgggca tatccgcaag attatgaaaa ttcttattac gtaaaaaatt aaccacttca
    32521 tttttacgct gtatggcacg gacaaaatct gtgtgctgct gtgcgtcatg aaccaatgtt
    32581 ttggttggga tacagccgat attaatacag gtcccgccat acattgcatt tgattgttcg
    32641 atgagagcca cacgccaacc tgcttttgcc agcgtgacgg ctaatgtttt tccagccttg
    32701 ccaaaaccaa taataactgc ctgatattta ttcatgatga tttcctgtcg aaacgtgttc
    32761 atttgaaatc atgactatag gacgcaaaag gtgacgctgc caacttactg atttagtgta
    32821 tgatggtgtt tttgaggtgc tccagtggct tctgtttcta tcagctgtcc ctcctgttca
    32881 gctactgacc ggggtggtgc gtaacggcaa aagcactgcc ggacatcagc gctatctctg
    32941 ctctcactgc cgtaaaacat ggcaactgca gttcacttac accgcttctc aacccggtac
    33001 gcaccagaaa atcattgata tggccatgaa tggcgttgga tgccgggcaa ctgcccgcat
    33061 tatgggcgtt agcctcaaca cgattttacg tcacttaaaa aactcaggcc gcagtcggta
    33121 acctcgcgca tacagccggg cagtgacgtc atcgtctgcg cggaaatgga cgaacagtgg
    33181 ggatacgtcg gggctaaatc gcgccagcgc tggctgtttt acgcgtatga caggctccgg
    33241 aagacggttg atgcgcacgt attcggtgaa cgcactatgg cgacgctggg gcgtcttatg
    33301 agcctgctgt caccctttga cgtggtgata tggatgacgg atggctggcc gctatatgaa
    33361 tcccgcctga agggaaagct gcacgtaatc agcaagcgat atacgcagcg aattgagcgg
    33421 cataacctga atctgaggca gcacctggca cggctgggac ggaagtcgct gtcgttctca
    33481 aaatcggtgg agctgcatga caaagtcatc gggcattatc tgaacataaa acactatcaa
    33541 taagttagag tcattaccca ttatcctgtg gtcacactct gccatgtgtt cggggttcat
    33601 cgcagcagct acagatactg gaaaaaccat cctgaaaaac cagacggcag acgggctgta
    33661 ttacgcagtc aggtacctga gctacatggc atcagccacg gttcggccgg agcaagaagc
    33721 atcgccacaa tggcaacccg gagaggctac cagatgggac gctggcttgc tggcaggctc
    33781 atgaaagagc tggggctggt cagctgtcag cagccgactc accggtataa acgtggtggt
    33841 catgaacatg ttgctatccc taactatctt gaacggcagt tcgccgtgac cgagccaaat
    33901 caggtgtggt gcggtgatgt ggcctatatc tggacgggta agcgctgggc gtacctcgcc
    33961 gttgttctcg acctgttcgc aagaaaacca gtgggctggg ccatgtcgtt ctcgccggac
    34021 agcaggctca ccatgaaagc gctggaaatg gcatgggaaa cccgtggtaa gcccggcggg
    34081 gtgatgttcc acagcgatca gggcagtcat tatacgagca ggcagttccg gcagttattg
    34141 tggcgatacc agatcagaca gagtatgagc cggcgcggaa actgctggga taacagccca
    34201 atggaacgct tcttcaggag tctgaagaac gaatggatgc cggtggtggg ttacgtaagc
    34261 ttcagcgagg cagctcacgc cataacggac tatatcgttg gatattacag cgcactaaga
    34321 ccgcacgaat ataacggtgg gttaccccca aacgaatcgg aaaatcgata ctggaaaaac
    34381 tctaactcgg aggccagttt ttgttgacca cttcaaacat gcttcgttca gatcccaaca
    34441 gagttttcac catcgcctgt aacagccgtc ctgctgcgtg attactccgc tcaacgggtt
    34501 gctggcgaca agtcaatacc tgttcgtgac aggtattgat tgaaccgttg tccctaacta
    34561 ataatgtgcc gacgatgcag gtgggaccgt ggtcccaggg agataacctg accggcgata
    34621 caggtgggac cgtggtccca gggagataac ctgaccggcg atacaggtgg gaccgtggtc
    34681 ccagggagat aacctgaccg gcgatacagg tgggaccgtg gtcccaggga gataacctga
    34741 ccggcgatac aggtgggacc gtggtcccag ggagataacc tgagcggcga tacagatggg
    34801 accgtggtcc cagagagaat attcaggcca gttatgtttt ctggcctgtg agaaaggaaa
    34861 tgaagtaaag ggagatcacc gtagactaaa gcgtgtccgc atcagactcc tggtttctca
    34921 agctccttaa gaatggcttc tattttctct atacactccg caggaatgcg ggacctatcc
    34981 aggttaagca ccattttatc gcccttatac aatgctgttg cccctggagc aaactgatga
    35041 cgtgagctca gattaactct tgatgcgggg gattgtttca gtacggatgt taaaagacta
    35101 atgacctctt cagcttcaaa gattagtccc gctttcttct gatcgtggag agtctcagcc
    35161 tgctgcttca gtaattcttc tttatctgca aaagccttct gaagggcttc acctgaccgg
    35221 gcagacagtt ctccaggatg tgcaaacagg gcaacaacgg atttaggcaa tttggccgta
    35281 ttgatacagc gggtaatgat cttacgagag atgttttccg catcggcaag cgcagaaata
    35341 tttcctgcaa actcattctg cagccggctt gtataacgca ggccacgttc ataagcactc
    35401 gtcggccgat aatcgttacc cagtcgggac aatgcagcca tctgctcatc gtccagttca
    35461 ccaaccagaa cgcgataatc actttccgtc aggattgcgg ctttacggcg acggctgccg
    35521 tcggcaattt ctatgacatc agaaacccgg cggccgaaag ctggagtctg ctgaccggtc
    35581 agtaaaaatg aaggaatgag atcatccaga gcatcttcgg taagtagttc ctgatcgcgc
    35641 tcattgcctg accatacgcg tgaagcgctc tcaacagagt ctccccggag cacctcaagg
    35701 gtaaatttta cttcccgtcc acataccgga agagagattg cattaccgcg ggccatagca
    35761 cccacgcgcg caattaatga atccaccatc ggcgcggccg gcgccggtga tgaagtatct
    35821 tcagtcgatt gagtatgtgt ggtatgtctt ggaatgacag gagcacgctt cattatctaa
    35881 tctcccagcg tggtttaatc agacgatcaa aaatctcatt gcaaacaggc tcccagatag
    35941 agagggcatt acgccaggca ccggttgaag aacgttgatc aatagcctgt tcaaaaacgg
    36001 ttctcatacg gatctgacct ttaccgactt catccgtttc gcgcacaaca tttttaagga
    36061 ccatgcttcc ccaggcatcc cgaatttgtt cttccatcca cggggactgt gagccattat
    36121 tattactgta tttggtaagc agaatacgga catctggctc gaagccttta agatccacgt
    36181 tcttaagcag gtcacgaagc atatcgaaaa actgcagtgc ggaggtgtag tcgaacagct
    36241 ctgccggagt agggacaatc agaacatcag cagcgcatac aacatttatc gtaccgatac
    36301 caaggttagg tgcactgtcg ataactatca cgtcataatc atgagcgaca gtttcaatgg
    36361 ccagacggag catcaggtgc gggtcagcag gtaatttgcc ttcgtcaaat ttccccatca
    36421 gctcggtttc aatgcggtgc agtgccagac aggacgggat gatatcaagg ccaggccagc
    36481 aggtgggctt tatagcgtag ctggcgtcat ccttttcccc aagataaaag ggtaggagag
    36541 tgtcctcagc atgaatatga agatcgggca cccatccgtg atacatagaa gcagttccct
    36601 gtgggtcatt gccttcaaca agcagaacac ggagtccttt cagagcaaga tcctgagcca
    36661 ggtgaacgga tactgaggtt ttgtaaacac cacctttgtg agctgcaacg ccaatcaccg
    36721 gcggaaacgc atcttcagca cggcgcagtc gtgtaccaaa tacatcccgc atgtgattga
    36781 tttgttcgat ggtataacca acgcgttgct ctactctccc acgggtttcc atatcagggt
    36841 gcggcagccg gccagctttc tcggcatccc tgatagcctg agatgacacg ccaactaaat
    36901 ctgccgcttc accaatcctc cagcgccggg ttattttccg ggcttccgga ctgtcatcat
    36961 taaactgtgc aatggcgatt gctttcgtca tttcatgacc agcacttatg cactggttga
    37021 gtgtatccat gagtcccata ctgaacatcc tttaaccatc actttgcatt attttattaa
    37081 atcttggaat ttattgcaaa gcaacaataa aatcgcaaag cacacgaaaa agtgcaaagt
    37141 gaaccacatt ggctaatgaa agaacgcagg ggattacaaa agagtacata ctgcagtcaa
    37201 tattaatcac tgccgctcgc cgcagtaagc gatctcacaa agtgagaaag cggcgaggaa
    37261 gcggaaaatc acagaactca cagattgcac gtacgtcggg ttgctaaaga tgactcggga
    37321 tcagccagtt ataatgaaat tgactgcggt atgtaatata ttgactatgg tatgatgctt
    37381 accgcatctg taggaaagac gactcagcat accgcagtca atgtttcatt gttgtacctg
    37441 tagatctcaa tcttccagag cgtattcagg aaaatcaggc cagggttctg gatatctggt
    37501 gtggcgcttc cggccttgta tctgggttat tcatggtctc gatccaataa ttgatcccaa
    37561 ggagatcata gtgagatcca aaagagatcc ccggatcgct ccagcatgcg ctgtaactgg
    37621 ctttaacgtc tgtctggatc gactgcggaa tgtaaaatgt tgactgttat atgcataatc
    37681 taatactgtg atatgcaacg gtatttactg aggtatgtat atctgttgac tgcgatacgt
    37741 attactacat ccttttgtgg ataaccgttg aggatcaag
//
