LOCUS       NZ_CP089322            40605 bp    DNA     circular CON 17-FEB-2024
DEFINITION  Enterococcus faecium strain NMVRE-001 plasmid p3, complete sequence.
ACCESSION   NZ_CP089322
VERSION     NZ_CP089322.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN23828484
            Assembly: GCF_021228615.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40605)
  AUTHORS   Pincus,N.B. and Bachta,K.E.R.
  TITLE     Enterococcus faecium clinical isolates
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 40605)
  AUTHORS   Pincus,N.B. and Bachta,K.E.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2021) Medicine (Infectious Diseases), Northwestern
            University Feinberg School of Medicine, 645 N Michigan Avenue,
            Chicago, IL 60611, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 29-MAY-2021
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 60.0x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/17/2024 08:03:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,146
            CDSs (total)                      :: 3,053
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 93
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 47 of 141
            Pseudo Genes (incomplete)         :: 88 of 141
            Pseudo Genes (internal stop)      :: 32 of 141
            Pseudo Genes (multiple problems)  :: 23 of 141
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP089322.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..40605
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="NMVRE-001"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /plasmid="p3"
                     /geo_loc_name="USA: Chicago, Illinois"
                     /lat_lon="41.89 N 87.62 W"
                     /collection_date="2021-02"
                     /collected_by="Clinical Microbiology Laboratory at
                     Northwestern"
     gene            1..1041
                     /locus_tag="LUB18_RS15320"
                     /old_locus_tag="LUB18_15320"
     CDS             1..1041
                     /locus_tag="LUB18_RS15320"
                     /old_locus_tag="LUB18_15320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_000997689.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLLK
                     DRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGRVN
                     KRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTTVIA
                     KIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVDIMKE
                     DSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELESYGIDA
                     DKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFNELPTVS
                     TENWLE"
                     /name="replication initiator protein A"
     gene            complement(1657..2337)
                     /locus_tag="LUB18_RS15325"
                     /old_locus_tag="LUB18_15325"
     CDS             complement(1657..2337)
                     /locus_tag="LUB18_RS15325"
                     /old_locus_tag="LUB18_15325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_002343844.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIGADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKLYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            2483..2566
                     /locus_tag="LUB18_RS15330"
                     /old_locus_tag="LUB18_15330"
     CDS             2483..2566
                     /locus_tag="LUB18_RS15330"
                     /old_locus_tag="LUB18_15330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]; GO:0031556 - transcriptional attenuation by ribosome
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="WP_001814874.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
                     /name="23S rRNA methyltransferase attenuation leader
                     peptide"
     gene            2691..3428
                     /gene="erm(B)"
                     /locus_tag="LUB18_RS15335"
                     /old_locus_tag="LUB18_15335"
     ARG             2692..3425
                     /name="erm(B)"
                     /gene="erm(B)"
                     /gene_name="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE/MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            <3598..3858
                     /locus_tag="LUB18_RS15340"
                     /old_locus_tag="LUB18_15340"
                     /pseudo=""
     CDS             <3598..3858
                     /locus_tag="LUB18_RS15340"
                     /old_locus_tag="LUB18_15340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /GO_component="GO:0005694 - chromosome [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /name="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            4021..>4686
                     /locus_tag="LUB18_RS15345"
                     /old_locus_tag="LUB18_15345"
                     /pseudo=""
     CDS             4021..>4686
                     /locus_tag="LUB18_RS15345"
                     /old_locus_tag="LUB18_15345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
                     /name="IS1182-like element IS1182 family transposase"
     gene            4722..4967
                     /locus_tag="LUB18_RS15350"
                     /old_locus_tag="LUB18_15350"
     CDS             4722..4967
                     /locus_tag="LUB18_RS15350"
                     /old_locus_tag="LUB18_15350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_000567888.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRLL
                     LGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
                     /name="single-stranded DNA-binding protein"
     gene            5070..5939
                     /locus_tag="LUB18_RS15355"
                     /old_locus_tag="LUB18_15355"
     CDS             5070..5939
                     /locus_tag="LUB18_RS15355"
                     /old_locus_tag="LUB18_15355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /protein_id="WP_000228166.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIYY
                     NSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIKRV
                     EQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETYPNA
                     LQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYCINEK
                     KAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINNFLNEE
                     SSDERKQI"
                     /name="nucleotidyltransferase domain-containing protein"
     gene            5920..6654
                     /locus_tag="LUB18_RS15360"
                     /old_locus_tag="LUB18_15360"
     CDS             5920..6654
                     /locus_tag="LUB18_RS15360"
                     /old_locus_tag="LUB18_15360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]; GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_000662263.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGKR
                     VLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDFPE
                     ESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNEKGE
                     ILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPENMMD
                     IPGMADEMRRPMMLIVSAKKKM"
                     /name="class I SAM-dependent methyltransferase"
     gene            6687..7599
                     /gene="ant(6)"
                     /locus_tag="LUB18_RS15365"
                     /old_locus_tag="LUB18_15365"
                     /pseudo=""
     CDS             6687..7599
                     /gene="ant(6)"
                     /locus_tag="LUB18_RS15365"
                     /old_locus_tag="LUB18_15365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="ant(6)"
     gene            7596..8138
                     /gene="sat4"
                     /locus_tag="LUB18_RS15370"
                     /old_locus_tag="LUB18_15370"
     ARG             7597..8135
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            8231..9025
                     /gene="aph(3')-IIIa"
                     /locus_tag="LUB18_RS15375"
                     /old_locus_tag="LUB18_15375"
     ARG             8232..9022
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            9301..9789
                     /locus_tag="LUB18_RS15380"
                     /old_locus_tag="LUB18_15380"
     CDS             9301..9789
                     /locus_tag="LUB18_RS15380"
                     /old_locus_tag="LUB18_15380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="WP_002349869.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLEE
                     AGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAMYK
                     IKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISVLLQSFK"
                     /name="HTH domain-containing protein"
     gene            complement(9819..10499)
                     /locus_tag="LUB18_RS15385"
                     /old_locus_tag="LUB18_15385"
     CDS             complement(9819..10499)
                     /locus_tag="LUB18_RS15385"
                     /old_locus_tag="LUB18_15385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(<10573..11847)
                     /locus_tag="LUB18_RS15390"
                     /old_locus_tag="LUB18_15390"
                     /pseudo=""
     CDS             complement(<10573..11847)
                     /locus_tag="LUB18_RS15390"
                     /old_locus_tag="LUB18_15390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4158 domain-containing protein"
                     /name="DUF4158 domain-containing protein"
     gene            11993..12568
                     /locus_tag="LUB18_RS15395"
                     /old_locus_tag="LUB18_15395"
     CDS             11993..12568
                     /locus_tag="LUB18_RS15395"
                     /old_locus_tag="LUB18_15395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001226076.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDREQ
                     LQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDNPY
                     SQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKLYKE
                     GNMTVNQICEITNVSRASLYRKLSEVNN"
                     /name="recombinase family protein"
     gene            12782..13477
                     /gene="vanR-A"
                     /locus_tag="LUB18_RS15400"
                     /old_locus_tag="LUB18_15400"
     ARG             12783..13474
                     /name="vanR-A"
                     /gene="vanR-A"
                     /gene_name="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            13455..14609
                     /locus_tag="LUB18_RS15405"
                     /old_locus_tag="LUB18_15405"
     CDS             13455..14609
                     /locus_tag="LUB18_RS15405"
                     /old_locus_tag="LUB18_15405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="WP_002305818.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGKL
                     GDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKYFD
                     EINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVMYLA
                     HDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRYNLQT
                     ITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFNNILKN
                     AAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSSDTGGAG
                     LGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
                     /name="vancomycin resistance histidine kinase VanS-A"
     gene            complement(14754..16049)
                     /locus_tag="LUB18_RS15410"
                     /old_locus_tag="LUB18_15410"
     CDS             complement(14754..16049)
                     /locus_tag="LUB18_RS15410"
                     /old_locus_tag="LUB18_15410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="WP_002297185.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHTC
                     RNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQSY
                     FVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSKRIL
                     PRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEEVKFL
                     VTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKSQAEKL
                     KKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAYPYFHEL
                     VEAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITNAMIYPYTNGKIEAKNT
                     HIKTMKRVSYGFKSFENMRIRIFLINQLIKVR"
                     /name="ISL3-like element ISEfa5 family transposase"
     gene            complement(16229..17521)
                     /locus_tag="LUB18_RS15415"
                     /old_locus_tag="LUB18_15415"
     CDS             complement(16229..17521)
                     /locus_tag="LUB18_RS15415"
                     /old_locus_tag="LUB18_15415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1251 family transposase"
                     /protein_id="WP_000122610.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIYT
                     AQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADTSV
                     AKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTPLPK
                     VLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREAVEWI
                     VIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQKHYQLG
                     KQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQLYQDFL
                     YAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPLECLNNHI
                     KVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
                     /name="ISL3-like element IS1251 family transposase"
     gene            17853..18821
                     /locus_tag="LUB18_RS15420"
                     /old_locus_tag="LUB18_15420"
     CDS             17853..18821
                     /locus_tag="LUB18_RS15420"
                     /old_locus_tag="LUB18_15420"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="WP_001059542.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKSA
                     PFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAYSP
                     DSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKAVIE
                     RLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQRMKQ
                     GAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQFLLKL
                     QRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
                     /name="D-lactate dehydrogenase VanH-A"
     gene            18814..19845
                     /gene="vanA"
                     /locus_tag="LUB18_RS15425"
                     /old_locus_tag="LUB18_15425"
     ARG             18815..19842
                     /name="vanA"
                     /gene="vanA"
                     /gene_name="D-alanine--(R)-lactate ligase VanA"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="99.71"
                     /coverage="100.0"
     gene            19851..20459
                     /locus_tag="LUB18_RS15430"
                     /old_locus_tag="LUB18_15430"
     CDS             19851..20459
                     /locus_tag="LUB18_RS15430"
                     /old_locus_tag="LUB18_15430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="WP_000402348.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTYE
                     LAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRTEM
                     ISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEAQNR
                     RRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
                     /name="D-Ala-D-Ala dipeptidase VanX-A"
     gene            complement(20623..21303)
                     /locus_tag="LUB18_RS15435"
                     /old_locus_tag="LUB18_15435"
     CDS             complement(20623..21303)
                     /locus_tag="LUB18_RS15435"
                     /old_locus_tag="LUB18_15435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            21391..22302
                     /locus_tag="LUB18_RS15440"
                     /old_locus_tag="LUB18_15440"
     CDS             21391..22302
                     /locus_tag="LUB18_RS15440"
                     /old_locus_tag="LUB18_15440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="WP_001812592.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHLE
                     NSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLLDS
                     NIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGYSEH
                     NSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIRYVGL
                     PHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNLRYEIS
                     GNNIDGVIVTVFPGSTHTNSRR"
                     /name="D-Ala-D-Ala carboxypeptidase VanY-A"
     gene            22455..22940
                     /gene="vanZ-A"
                     /locus_tag="LUB18_RS15445"
                     /old_locus_tag="LUB18_15445"
     ARG             22456..22937
                     /name="vanZ-A"
                     /gene="vanZ-A"
                     /gene_name="glycopeptide resistance protein VanZ-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(23227..23556)
                     /locus_tag="LUB18_RS15450"
                     /old_locus_tag="LUB18_15450"
     CDS             complement(23227..23556)
                     /locus_tag="LUB18_RS15450"
                     /old_locus_tag="LUB18_15450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000754864.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIKI
                     FYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDILS
                     AIRVF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            23861..24190
                     /locus_tag="LUB18_RS15455"
                     /old_locus_tag="LUB18_15455"
     CDS             23861..24190
                     /locus_tag="LUB18_RS15455"
                     /old_locus_tag="LUB18_15455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000629052.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEPK
                     KEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEELA
                     AEIGL"
                     /name="hypothetical protein"
     gene            24180..24467
                     /locus_tag="LUB18_RS15460"
                     /old_locus_tag="LUB18_15460"
     CDS             24180..24467
                     /locus_tag="LUB18_RS15460"
                     /old_locus_tag="LUB18_15460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000312841.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQK
                     TGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(24746..25309)
                     /locus_tag="LUB18_RS15465"
                     /old_locus_tag="LUB18_15465"
     CDS             complement(24746..25309)
                     /locus_tag="LUB18_RS15465"
                     /old_locus_tag="LUB18_15465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000017403.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAVR
                     PQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTPHG
                     RLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQVYS
                     VKEITEMTGISKATLYRYLKDNRE"
                     /name="recombinase family protein"
     gene            25952..26905
                     /locus_tag="LUB18_RS15470"
                     /old_locus_tag="LUB18_15470"
     CDS             25952..26905
                     /locus_tag="LUB18_RS15470"
                     /old_locus_tag="LUB18_15470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="WP_000222571.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNFL
                     KCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEKRSTEGWTPDVIIGRAERTFSCS
                     ISTLYRRFKTGEFNVLHLPMQGKRKPNGYKEKRGKQAFKRNISERKKDYVVFEEEFGHL
                     EGDTIVGIHHKSAVITLVERLSKAIIVLKPEGRKAVDIENSINEWLQSVPKNLFKSITF
                     DCGKEFSNWKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRKDGLPKEMDFNQVNQGF
                     ISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA"
                     /name="IS30 family transposase"
     gene            27301..27705
                     /gene="tnpA"
                     /locus_tag="LUB18_RS15475"
                     /old_locus_tag="LUB18_15475"
     CDS             27301..27705
                     /gene="tnpA"
                     /locus_tag="LUB18_RS15475"
                     /old_locus_tag="LUB18_15475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="WP_002287522.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERISE
                     SYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKEMF
                     WSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
                     /name="tnpA"
     gene            27722..28870
                     /gene="tnpB"
                     /locus_tag="LUB18_RS15480"
                     /old_locus_tag="LUB18_15480"
     CDS             27722..28870
                     /gene="tnpB"
                     /locus_tag="LUB18_RS15480"
                     /old_locus_tag="LUB18_15480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element RNA-guided
                     endonuclease TnpB"
                     /protein_id="WP_002287525.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYEE
                     VKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRFKS
                     KKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSSGKY
                     YISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQRKLS
                     RRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDIICIED
                     LNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICSECGHKD
                     GKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
                     /name="tnpB"
     gene            29110..30249
                     /locus_tag="LUB18_RS15485"
                     /old_locus_tag="LUB18_15485"
     CDS             29110..30249
                     /locus_tag="LUB18_RS15485"
                     /old_locus_tag="LUB18_15485"
                     /inference="COORDINATES: protein motif:HMM:NF012307.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="WP_269755793.1"
                     /translation="MLNWWEYFEQKSLAQNIKYQYCMFTDIADCYPSIYTHSITWAMYG
                     KEKVKNDENKCSGSLGDKIDKKISGMQHNQTNGIPQGSVLMDFVAEIVLGYVDLRLSKE
                     LKKLENLKDYKVLRYRDDYRIFSNNRNDLEQIMKVLSEVLYDLNFKLNSSKTKLSDDII
                     IDSIKKDKLYWEEIKASIRMNATNLDGDREIRYSINLQKHLLEIKKLADKHPNSGQLKK
                     ALSEFNKERIIKITSKPNDLLPLIGILVDIMINNPGSLPQCVLIIGQLLNFENESKARE
                     IVEMIINKYALKPNTEFMMIWFQRLTTIFGEMFDSVLSSEFVSKIKDPVSNQMFSVDWL
                     NEDAKKSFYEGTIKDEEKYIKMSKKIYITEFDDFNDYPF"
                     /name="RNA-directed DNA polymerase"
     gene            30587..31825
                     /locus_tag="LUB18_RS15490"
                     /old_locus_tag="LUB18_15490"
     CDS             30587..31825
                     /locus_tag="LUB18_RS15490"
                     /old_locus_tag="LUB18_15490"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /GO_function="GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA]; GO:0009007 -
                     site-specific DNA-methyltransferase (adenine-specific)
                     activity [Evidence IEA]"
                     /GO_process="GO:0006306 - DNA methylation [Evidence IEA];
                     GO:0009307 - DNA restriction-modification system [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M"
                     /protein_id="WP_265098352.1"
                     /translation="MTEQIEKNSKSLYQALWNSADILRSKMDANEYKSYLLGLVFYKYL
                     SDNMLRYVSVLLEEETDDLNKAQDLYVEAFKDADIKDDLLYELKDEFSYTIAPALTFTA
                     QVAAIHDGSFQLEDLVQGFRDIEQSSENFENLFEDIDLYSKKLGSTPQKQNKTIADVMK
                     ELEGLNMAGHAGDVLGDAYEYLIGQFASESGKKAGEFYTPQPVAKLMTQIVLQGKEDKK
                     GFSVYDATMGSGSLLLNAKKYSHQPGTISYFGQELNTSTYNLARMMARMNMILHGVPIA
                     NQHLHNADTLDQDWPTEEPTNFDGVLMNPPYSAKWSADKGFLDDPRFSAYGVLAPKSKA
                     DFAFLLHGYYHLKDTGVMAIVLPHGVLFRGGAEGKIRKALLENGAIDTVIGLPANIFFN
                     TSIRFCCKVLNKE"
                     /name="type I restriction-modification system subunit M"
     gene            complement(31848..32528)
                     /locus_tag="LUB18_RS15495"
                     /old_locus_tag="LUB18_15495"
     CDS             complement(31848..32528)
                     /locus_tag="LUB18_RS15495"
                     /old_locus_tag="LUB18_15495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(32582..33841)
                     /locus_tag="LUB18_RS15500"
                     /old_locus_tag="LUB18_15500"
     CDS             complement(32582..33841)
                     /locus_tag="LUB18_RS15500"
                     /old_locus_tag="LUB18_15500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1251 family transposase"
                     /protein_id="WP_016171138.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIYT
                     AQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADTSV
                     AKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTPLPK
                     VLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREAVEWI
                     VIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQKHYQLG
                     KQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQLYQDFL
                     YAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPLECLNNHI
                     KVLKRNAYGFRSFYGSVAKF"
                     /name="ISL3-like element IS1251 family transposase"
     gene            complement(33991..34605)
                     /locus_tag="LUB18_RS15505"
                     /old_locus_tag="LUB18_15505"
     CDS             complement(33991..34605)
                     /locus_tag="LUB18_RS15505"
                     /old_locus_tag="LUB18_15505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_010782630.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRPV
                     FQEALDYVRDQDIFIVEAIDRLGRNYDEIITSVNYLKKKNVKLIITSLPIMAEAIGNPL
                     LDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQRRL
                     VYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
                     /name="recombinase family protein"
     gene            34919..35341
                     /locus_tag="LUB18_RS15510"
                     /old_locus_tag="LUB18_15510"
     CDS             34919..35341
                     /locus_tag="LUB18_RS15510"
                     /old_locus_tag="LUB18_15510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002288787.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELTP
                     LDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSRNW
                     KEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
                     /name="hypothetical protein"
     gene            35351..35554
                     /locus_tag="LUB18_RS15515"
                     /old_locus_tag="LUB18_15515"
     CDS             35351..35554
                     /locus_tag="LUB18_RS15515"
                     /old_locus_tag="LUB18_15515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002299573.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKSI
                     SNLEDSEEKRKKRDQKTYQKEK"
                     /name="hypothetical protein"
     gene            35765..36349
                     /locus_tag="LUB18_RS15520"
                     /old_locus_tag="LUB18_15520"
     CDS             35765..36349
                     /locus_tag="LUB18_RS15520"
                     /old_locus_tag="LUB18_15520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_002299575.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPGL
                     EMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSSTGQ
                     LMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSGTPI
                     KTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
                     /name="recombinase family protein"
     gene            36518..37843
                     /locus_tag="LUB18_RS15525"
                     /old_locus_tag="LUB18_15525"
     CDS             36518..37843
                     /locus_tag="LUB18_RS15525"
                     /old_locus_tag="LUB18_15525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="WP_016171137.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRSD
                     NTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNIFR
                     RYVADEDLLIYSIDESILKVTKSLNLFTTEETRSQRRKKLAQMIQERIKEELGLIATVG
                     VGDNPLLAKLALDNEAKHNEGFIAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRLNQMG
                     ILSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQVLPRD
                     YTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKIPITDNT
                     KELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEENLDKIIDK
                     IRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
                     /name="Y-family DNA polymerase"
     gene            37836..38186
                     /locus_tag="LUB18_RS15530"
                     /old_locus_tag="LUB18_15530"
     CDS             37836..38186
                     /locus_tag="LUB18_RS15530"
                     /old_locus_tag="LUB18_15530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000568378.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTEE
                     IAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIRHI
                     EFYQDNKWSRLE"
                     /name="hypothetical protein"
     gene            38183..38362
                     /locus_tag="LUB18_RS15535"
                     /old_locus_tag="LUB18_15535"
     CDS             38183..38362
                     /locus_tag="LUB18_RS15535"
                     /old_locus_tag="LUB18_15535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001021554.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAAA
                     GYHNFRFYIFPLYI"
                     /name="hypothetical protein"
     gene            38498..38788
                     /locus_tag="LUB18_RS15540"
                     /old_locus_tag="LUB18_15540"
     CDS             38498..38788
                     /locus_tag="LUB18_RS15540"
                     /old_locus_tag="LUB18_15540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000026576.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITRQ
                     RRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
                     /name="hypothetical protein"
     gene            39156..39944
                     /locus_tag="LUB18_RS15545"
                     /old_locus_tag="LUB18_15545"
     CDS             39156..39944
                     /locus_tag="LUB18_RS15545"
                     /old_locus_tag="LUB18_15545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /GO_process="GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000101106.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQGN
                     ATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVGSE
                     HRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKLSET
                     IETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRRTITVD
                     EAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
                     /name="AAA family ATPase"
     gene            39931..40257
                     /locus_tag="LUB18_RS15550"
                     /old_locus_tag="LUB18_15550"
     CDS             39931..40257
                     /locus_tag="LUB18_RS15550"
                     /old_locus_tag="LUB18_15550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000796719.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKDQ
                     GSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLAKK
                     QNKI"
                     /name="hypothetical protein"
     ARG             17854..18818
                     /name="vanH-A"
                     /gene="vanH-A"
                     /gene_name="D-lactate dehydrogenase VanH-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             13456..14606
                     /name="vanS-A"
                     /gene="vanS-A"
                     /gene_name="vancomycin resistance histidine kinase VanS-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             21392..22299
                     /name="vanY-A"
                     /gene="vanY-A"
                     /gene_name="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             19852..20456
                     /name="vanX-A"
                     /gene="vanX-A"
                     /gene_name="D-Ala-D-Ala dipeptidase VanX-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             6743..7596
                     /name="ant(6)-Ia"
                     /gene="ant(6)-Ia"
                     /gene_name="aminoglycoside nucleotidyltransferase
                     ANT(6)-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="99.65"
                     /coverage="94.37"
     ARG             12783..13477
                     /name="vanR gene in vanA cluster"
                     /gene="vanR gene in vanA cluster"
                     /gene_name="glycopeptide resistance gene cluster; vanR"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             17854..18821
                     /name="vanH gene in vanA cluster"
                     /gene="vanH gene in vanA cluster"
                     /gene_name="vanH; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             19852..20459
                     /name="vanX gene in vanA cluster"
                     /gene="vanX gene in vanA cluster"
                     /gene_name="vanX; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="99.5"
                     /coverage="100.0"
     ARG             21392..22302
                     /name="vanY gene in vanA cluster"
                     /gene="vanY gene in vanA cluster"
                     /gene_name="vanY; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             22456..22940
                     /name="vanZ gene in vanA cluster"
                     /gene="vanZ gene in vanA cluster"
                     /gene_name="vanZ; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             13468..14609
                     /name="vanS gene in vanA cluster"
                     /gene="vanS gene in vanA cluster"
                     /gene_name="vanS; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="99.74"
                     /coverage="98.96"
     ARG             7597..8138
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="99.44"
                     /coverage="100.0"
     ARG             6740..7599
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="103.62"
     ARG             2692..3428
                     /name="ErmB"
                     /gene="ErmB"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="98.37"
                     /coverage="98.79"
     Typing          2..1041
                     /name="rep_cluster_889"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgaatgatt ttaattatta caaatcaaaa gaaatttatc gtgaaaaata ttatcaaatg
       61 cctaaggtat tttttactaa cgaaaaatac atggatctat caaatgatgc aaaaattgct
      121 tatatgctac ttaaagatcg atttgattat tcagtcaaaa ataactgggt agattctgat
      181 gataatatat ttttcatatt cacagttgaa gaattaatga aattgttaca atgccgcgaa
      241 ggtaaagtat ctaaaatcaa aaaggaatta gaaaaagcag gtcttctgaa acagaagaga
      301 ggaagagtaa ataaacgtga cggtaagatt gaatccatgc ctaatttatt gtacttaggc
      361 aagccagaag taacgaatca agacgtcttt aaaatcatgg aagaggaaga caatactgat
      421 accaccgtaa ttgcgaaaat cgcaaatacg gcaaaaccgc gagaaatcaa tgataccacc
      481 gtaattgcga aaatcgcaaa tacggcaaaa tccagtcata tcaaggactc aaccgtaatt
      541 gcgaaaatcg cagacaatct attctattct aattctatag acactaatag acacataata
      601 gacactgaaa ctgatcagtt acaaaatcaa gttttactag ataacttcgt cgacatcatg
      661 aaagaggaca gtataaatac atttgtacca gaaaatgtat taaacttgat aaaaacattt
      721 tctagtactt acgaagacgc tcaaaaaacc gtccaaacta ttcataatgc aaagaaaaaa
      781 gctgaagaat tagagcaaac agttgttgtt tatgaagaac tggaatctta tggaattgat
      841 gctgacaaag gattatatat gactttgctg aaagcttatc aaaaacaaaa aactgaaaaa
      901 gtaaacaatt tgcagaatct aattttcgtt tatgtaaaaa attggtttgt cgaaaaagct
      961 attgcggcaa agcttgcaaa cgaacaaaga gaaacattta acgaattacc aacagttagt
     1021 acggaaaatt ggctagagta gttgataaaa agcgatcact ataaaaatga tcaattttaa
     1081 attagaactt ttttatgatt ttaattttat tacaaatgtt acaaataaat agctattatt
     1141 ccggagtttt tagattaaaa gtttatgaaa acaatcacaa acgtaggttt taaagtcata
     1201 atcgttagat attttagtta tttttcattc aaaaaaatag ggaactagtg tttgcatatg
     1261 tgcttttttg agttataata attcatgaag agaggtaatt cacttatttc cccaagctga
     1321 aaagcctgat attacttctt ttcaggcagt gctgctaata ttcaattaca cttttttgta
     1381 tatttttagt tgttttaaat ttaattgtct gatatgcttg tgatgaattg attttcgttc
     1441 tgcacttttg gacgataaat tgtgataatt gaaaatacaa aaaaaagaaa ggcccctgta
     1501 aggctcggga gactggtaat ctccgtcagt gtcctacagg aaagcattaa gatgacgcct
     1561 taatgcgtgc ccttcagtgt tacggtatta cccgcaacgg acggttctgt tgcaaagttt
     1621 taaataaaga ataaaatccc ttacggtatc tatgatttaa gctgggattc ccaataatac
     1681 cttgatttca gtacagaccg aaaacccgaa gagagtgcct tcttttcggg ttttcttata
     1741 taatcctcga atggcttcca tgcctttaat cgtggtagag gcagtgcgta aacttcgata
     1801 taatttattg cgtctcttta ctggacgatg gtcttgttca atcaaattat tcaggtattt
     1861 aatggtacga tgttctgtcc cttgataaaa gccgtattct tttagtttct taaaggcact
     1921 tgtaatagag ggggctttat ctgtgactac aaccttcggt tcatcaaact gcttcactaa
     1981 ccgcttaaga aaagcatagg ctgcttgtgt gtcccgtttt ttacgtaacc aaatatccaa
     2041 ggttaaacca tctgcaccga tggctcgata caaataatgc cattttcctt taattttgat
     2101 gtacgtttca tccattttcc atgaataaaa ggatttttta tttttctttt tccaaatttg
     2161 atagagtagt ttgccatatt cttgcaccca acgataaatc gtcgtatgag aaacgttaat
     2221 gccacgatca tataagattt cttgaacttc acgatagcta aggttataac gaagatagta
     2281 gcccacggct acaataatca catcctgctg aaattgcttt cctttaaaat gattcatcgt
     2341 cattcctcct gctatctttt tctattattc taccttattt gatagtagat ttaaaacttt
     2401 gcaacagaac cattttgtgt ataataggaa ttgaagttaa attagatgct aaaaatttgt
     2461 aattaagaag gagggattcg tcatgttggt attccaaatg cgtaatgtag ataaaacatc
     2521 tactgttttg aaacagacta aaaacagtga ttacgcagat aaataaatac gttagattaa
     2581 ttcctaccag tgactaatct tatgactttt taaacagata actaaaatta caaacaaatc
     2641 gtttaacttc tgtatttatt tacagatgta ataacttcag gagtgattac atgaacaaaa
     2701 atataaaata ttctcaaaac tttttaacga gtgaaaaagt actcaaccaa ataataaaac
     2761 aattgaattt aaaagaaacc gataccgttt acgaaattgg aacaggtaaa gggcatttaa
     2821 cgacgaaact ggctaaaata agtaaacagg taacgtctat tgaattagac agtcatctat
     2881 tcaacttatc gtcagaaaaa ttaaaactga acattcgtgt cactttaatt caccaagata
     2941 ttctacagtt tcaattccct aacaaacaga ggtataaaat tgttgggagt attccttacc
     3001 atttaagcac acaaattatt aaaaaagtgg tttttgaaag ccatgcgtct gacatctatc
     3061 tgattgttga agaaggattc tacaagcgta ccttggatat tcaccgaaca ctagggttgc
     3121 tcttgcacac tcaagtctcg attcagcaat tgcttaagct gccagcggaa tgctttcatc
     3181 ctaaaccaaa agtaaacagt gtcttaataa aacttacccg ccataccaca gatgttccag
     3241 ataaatattg gaagctatat acgtactttg tttcaaaatg ggtcaatcga gaatatcgtc
     3301 aactgtttac taaaaatcag tttcatcaag caatgaaaca cgccaaagta aacaatttaa
     3361 gtaccgttac ttatgagcaa gtattgtcta tttttaatag ttatctatta tttaacggga
     3421 ggaaataatt ctatgagtcg cttttttaaa tttggaaagt tacacgttac taaagggaat
     3481 ggagataaat tattagatat actactgaca gcttccaaga agctaaagag gtccctagcg
     3541 cctacgggga atttgtatcg ataaggggta caaattccca ctaagcgctc gggacccctt
     3601 gtaggaaaat gtcctaagtg tggcaacaat attgtattaa aaaaatcgtt ttatggttgt
     3661 tcaaattatc ctgaatgtaa gtttacttta gctgaacatt ttagaaagaa aaaactaacc
     3721 aaaacgaatg taaaagaatt actggaggga aaagaaaccc tggtaaaagg aatcaaaaac
     3781 aaagagaaaa agccctacaa tgccgttgta aaaattgggg aaaagggata tattgatttt
     3841 atctcttttt caaaataaac atggggctga cccaaaagta gctcctatat gaaaaataga
     3901 ggtctttcca tttagatagt agtggaaaga cctctattta tcttttgaaa gtgaatacaa
     3961 aaataaagca cactctgcta taatataggt gattaatcca tttgagagag gtgctttatc
     4021 atgtatcaaa attataccat aaaccaactt tgtttgccta tagatcttga aattaaatta
     4081 gaagaaaatg attttgctca tgccattgtg cagtttgttg actctattcc cgatgaagtc
     4141 tttcttcctt attatcaatc tatgggtaga ccccaatatc atcctcgtat gctactttcc
     4201 attattcttt gtgcctatat tcaaggggtt tattcgggcc gccaaataca aaatatgctg
     4261 atagatagta ttcggatgcg ctacttatct caagagcaat tccctaactt tcgtactatt
     4321 aatcgttttc gcgttcatcc gattatgaac gatattctag atcattcatt tgttcaattt
     4381 cgtgagctac tggttcaaag tggcttaatc agtggcagtg ctctatacat tgatggtaca
     4441 aaaattgaag cggatgcgaa taaatactct ttcgtttgga aaaaaagtat tttaaagtat
     4501 aaggatagcc ttgatcaaaa agcccttgaa aactaccaac aaatggtgga aacaaaaatc
     4561 ttacctgagt taatagatga tttaaaggat gaactttcta tagaagagat tgaaaggatt
     4621 cgtcaatctt tggaagaaaa ggaaaatcaa ttaattgaag cgattgacca aaccgaaaca
     4681 gtagaagggg gctgacccat tattaataag gagtggacaa catgattgat gtaaatgagc
     4741 tattggaaga agctattaga gaaactgaaa atctaaatga tggcgaagtt tttcttgtta
     4801 aagatttatt caagggatat gtggggaata ggatacccag aaaggatcga cttctgcttg
     4861 gaacgttatt tttaaaccat gttagcaaaa tgaatggtaa tttaaaggct attgaaaaga
     4921 cttcatctaa tcagcagagg tataaaaaga caattgataa gttttaacta tcttttgtga
     4981 aattaaaaaa attataaata tgttgagtag aagcaaaaga tttggcttgg aatttttaca
     5041 gcagtgaatc gataaaagga gcatgcttga tggtagataa tattattaaa tcagtagcag
     5101 agaaattatc ctctctgtct tatatagaag gtattgtttt aggtggttca cgtgcaaggg
     5161 gcacccatac agaggattcg gatatagata tcggcatcta ttacaattca gaatcatttg
     5221 acataaatac tattaatcaa ttcgctacaa agctggatga tgagcataga aataaccttg
     5281 ttgtacctcc cggagcatgg ggtgattgga ttaatggcgg cggatggtta gtcataaacg
     5341 ggtatcatgt ggatttaatt ttacgtgata ttaaacgtgt ggaacaaata atgaaagata
     5401 cagagcacgg aattgttact gccaattatc agactgggca tccccatggt tatattagtg
     5461 caatgtatcg aggagaatta gcgattagca aaatactata tgctaagaat gaaagcttat
     5521 gcgaattaaa aaaacaggca gaaacttatc ccaatgcttt gcagaaaagt ttagttaact
     5581 tttttatgtt tgaagcaggg ttctctttaa tgtttgtaaa agcaaattcg ggaacagacg
     5641 ataaatatta tattgcgggt catgtttttc gtatagtttc atgtttaaat caagtgttat
     5701 ttgcatgtaa taatgcttat tgtatcaacg aaaagaaagc tataaaactg cttgaaactt
     5761 ttgaacataa acctgaaaaa tataccgaga aggtaaatca tatttttgaa gtactcggta
     5821 tctcactttt tgaatgctac gacatgaccg agaagcttta taatgaagtg aatgaaattg
     5881 tatcggagat aaataacttt ttaaacgagg agagttcaga tgaaagaaaa caaatatgat
     5941 gataatatat tttttcaaaa atacagtcaa atgagtcgct cgcagaaagg actggctggt
     6001 gcgggagaat gggagacttt gaaaaagatg ctacctgatt ttaagggtaa gcgtgtgctt
     6061 gatttaggat gcggctatgg atggcactgt atatatgcga tggaaaacgg tgcttcctct
     6121 gtagtaggtg ttgatatttc tcataaaatg ctcgaagtag caaaaggaaa aacccatttt
     6181 ccacagattg aatatgaatg ctgtgccata gaagatgtgg atttcccaga ggagagcttt
     6241 gatgtaatac taagttcgct tgcgtttcat tatgtagcag actatgagaa tttaataaaa
     6301 aagatatata ggatgctgaa ggctggtggc aatttagttt ttacagttga acatcctgtt
     6361 tttactgctc atggaacaca agactggtat tataacgaaa aaggagaaat actgcatttc
     6421 ccggtggaca attattatta tgagggcaaa cggacagcta tgtttttgga agaaaaggtt
     6481 acaaaatatc atagaacact gaccacatat ctaaatacac tgctttcaaa tagttttata
     6541 ataaatcaga ttgtggagcc acagccgcca gagaacatga tggatattcc ggggatggcg
     6601 gatgaaatgc gacgcccaat gatgctgatt gtatcggcaa aaaagaagat gtaataatat
     6661 agaaaaaata aacgaggagt atgtaaatga gatcagaaaa agaaatgatg gatttagtac
     6721 tttctttagc agaacaggat gaacgaacgt attcgaattg tgacccttga ggggtcacgc
     6781 gcaaatatta atatacctaa agatgaattt caggattatg atattacata ttttgtaagt
     6841 gatatagaac cgtttatatc taatgatgac tggcttaatc aatttgggaa tataataatg
     6901 atgcaaaagc cggaggatat ggaattattc ccacctgaag aaaagggatt ttcctatctt
     6961 atgctatttg atgattacaa taaaattgat cttaccttat tgcccttgga agagttagat
     7021 aattacctaa agggcgataa attaataaag gttctaattg ataaagattg tagaattaaa
     7081 agggacatag ttccgactga tatagattat catgtaagaa agccaagcgc aagggagtat
     7141 gatgattgct gcaatgaatt ttggaatgta acaccttatg ttattaaagg attgtgccgt
     7201 aaggaaattt tatttgctat tgatcatttt aatcagattg ttcgccatga gctgctgaga
     7261 atgatatcat ggaaggtcgg catcgaaaca ggctttaaat taagtgtagg caagaactat
     7321 aagtttattg aaaggtatat atccgaggat ttgtgggaga aacttttgtc cacctaccgg
     7381 atggattcct atgaaaacat atgggaagca ttatttctat gccatcaatt gttcagggcg
     7441 gtatccggtg aggtggcgga aaggcttcat tatgcctatc cggagtatga taggaatata
     7501 acaaaatata ccagggacat gtataaaaaa tacactggta aaaccggctg cctggatagc
     7561 acatatgccg ctgatataga agagaggcgg gaacagtgat tacagaaatg aaagcagggc
     7621 acctgaaaga tatcgataaa cccagcgaac catttgaggt gataggtaag attataccga
     7681 ggtatgaaaa cgagaattgg acctttacag aattactcta tgaagcgcca tatttaaaaa
     7741 gctaccaaga cgaagaggat gaagaggatg aggaggcaga ttgccttgaa tatattgaca
     7801 atactgataa gataatatat ctttactacc aagacgataa atgcgtcgga aaagttaaac
     7861 tgcgaaaaaa ttggaaccgg tacgcttata tagaagatat cgccgtatgt aaggatttca
     7921 gggggcaagg cataggcagc gcgcttatca atatatctat agaatgggca aagcataaaa
     7981 acttgcatgg actaatgctt gaaacccagg acaataacct tatagcttgt aaattctatc
     8041 ataattgtgg tttcaaaatc ggctccgtcg atactatgtt atacgccaac tttgaaaaca
     8101 actttgaaaa agctgttttc tggtatttaa ggttttagaa tgcaaggaac agtgaattgg
     8161 agttcgtctt gttataatta gcttcttggg gtatctttaa atactgtaga aaagaggaag
     8221 gaaataataa atggctaaaa tgagaatatc accggaattg aaaaaactga tcgaaaaata
     8281 ccgctgcgta aaagatacgg aaggaatgtc tcctgctaag gtatataagc tggtgggaga
     8341 aaatgaaaac ctatatttaa aaatgacgga cagccggtat aaagggacca cctatgatgt
     8401 ggaacgggaa aaggacatga tgctatggct ggaaggaaag ctgcctgttc caaaggtcct
     8461 gcactttgaa cggcatgatg gctggagcaa tctgctcatg agtgaggccg atggcgtcct
     8521 ttgctcggaa gagtatgaag atgaacaaag ccctgaaaag attatcgagc tgtatgcgga
     8581 gtgcatcagg ctctttcact ccatcgacat atcggattgt ccctatacga atagcttaga
     8641 cagccgctta gccgaattgg attacttact gaataacgat ctggccgatg tggattgcga
     8701 aaactgggaa gaagacactc catttaaaga tccgcgcgag ctgtatgatt ttttaaagac
     8761 ggaaaagccc gaagaggaac ttgtcttttc ccacggcgac ctgggagaca gcaacatctt
     8821 tgtgaaagat ggcaaagtaa gtggctttat tgatcttggg agaagcggca gggcggacaa
     8881 gtggtatgac attgccttct gcgtccggtc gatcagggag gatatcgggg aagaacagta
     8941 tgtcgagcta ttttttgact tactggggat caagcctgat tgggagaaaa taaaatatta
     9001 tattttactg gatgaattgt tttagtacct agatttagat gtctaaaaag ctttaactac
     9061 aagcttttta gacatctaat cttttctgaa gtacatccgc aactgtccat actctgatgt
     9121 tttatatctt ttctaaaagt tcgctagata gagttctata ttagagatgt aaagagtttt
     9181 ggtgaagagg tttgtgagta tggcttttat aaccagggtg caatgagaag cactaacagc
     9241 agctagctta agaacgcata ggatatactt tttatggaag tcacagagga ggaataaaat
     9301 ttgaacagga ttaacagagt aacctctatt cttattcagc tgcaatcaaa aaaaataatt
     9361 cctgccaaag aaattgcaca gcgatttaat ataagcttaa ggacagttta cagagatatc
     9421 cggacacttg aagaagccgg aataccaatt ggatctgagg ccggaaaagg atattttctt
     9481 gtagagggct tcctacttcc gccggtaatg tttacagcgg cggaagtggg tgcattgatt
     9541 acagcaggga aatttttaaa ttgccatgga gatgaatcat ttataaagga ttttgattca
     9601 gctatgtata aaatcaaatc tattttgaag catggtgaaa aaaactatgc acaggagttg
     9661 gagaacagta ttaacgtgta cagcacatct ggacagaaaa atacattggc ggataacgtt
     9721 attgcagcaa ttcagactgc aatctgcaat aaaagggtaa tatcggttct gttgcaaagt
     9781 tttaaataaa gaataaaatc ccttacggta tctatgattt aagctgggat tcccaataat
     9841 accttgattt cagtacagac cgaaaacccg aagagagtgc cttcttttcg ggttttctta
     9901 tataatcctc gaatggcttc catgccttta atcgtggtag aggcagtgcg taaacttcga
     9961 tagaatttat tgcgtctctt tactggacga tggtcttgtt caatcaaatt attcaggtat
    10021 ttaatggtac gatgttctgt cccttgataa aagccgtatt cttttagttt cttaaaggca
    10081 cttgtaatag agggggcttt atctgtgact acaaccttcg gttcatcaaa ctgcttcact
    10141 aaccgcttaa gaaaagcata ggctgcttgt gtgtcccgtt ttttacgtaa ccaaatatcc
    10201 aaggttaaac catctgcatc gatggctcga tacaaataat gccattttcc tttaattttg
    10261 atgtacgttt catccatttt ccatgaataa aaggattttt tatttttctt tttccaaatt
    10321 tgatagagta gtttgccata ttcttgcacc caacgataaa tcgtcgtatg agaaacgtta
    10381 atgccacgat catataagat ttcttgaact tcacgatagc taaggttata acgaagatag
    10441 tagcccacgg ctacaataat cacatcctgc tgaaattgct ttcctttaaa atgattcatc
    10501 gtcattcctc ctgctatctt tttctattat tctaccttat ttgatagtag atttaaaact
    10561 ttgcaacaga acccctcgga taatctcaac agcttgtaaa agtggctcat ttgcctttgt
    10621 agaatgaaat tccaatactc ttaatagcgt tggcgtatat tttcttagtg aataaaaccg
    10681 tttttgcagt aagtctaaat aatcatagtc ggcaggacgt gcaagttcct gagcctcttc
    10741 tactgaagag acaaaggtat tccattcaat aaccgattct aaaaccttaa aaacgtctaa
    10801 tttttcctct cttgctttaa ttaatgcttg tccgatgttc gtaaagtgta taactttctc
    10861 atttagcttt ttaccgtttt gtttctggat ttcctcttga gccttacgac cttttgataa
    10921 caaactaagt atttgcctat catgaatttc aaacgcttta tccgttagct cctgagtaag
    10981 ttgtaataaa tagatggtta atatcgaata acgtttattt tcttgaaagt cacggaatgc
    11041 atacggctcg tatcttgagc ctaagcgaga cagctgcaac aggcggttac ggtgcaaatg
    11101 actaatttgc actgtttcta aatccattcc tcgtatgtat tcgagtcgtt ctattatttt
    11161 tagaaaagtt tcgggtgaag gatgacccgg tggctctttt aaccaaccca atatcgtttt
    11221 attggattcg gatggatgct gcgaggtaat aatcccttca agcttttttt tttgctcatt
    11281 tgttagagat ttactaaccg tattaaatag cttcttttca gccattgccc ttgcttccca
    11341 caccattctt tcaagtgtag tgatagcagg cagtataatt ttgttttttc ttagaaaatc
    11401 tatgcattca tgcagtagat gaatggcatc accattttcc aaagctaatt gatgaaggta
    11461 cttaaatgtc attcgatatt cactcagggt aaaagttaca aagtcgtatt cacttcgaat
    11521 ttctttcaaa tgatcccaaa gtgtattttc cctttgagga taatgatcaa gcgaggatgg
    11581 actaacacca atctgtttcg atatatattg tatgaccgaa tctgggatgc ttttgatatg
    11641 agtgtatggc caaccgggat accgaagaac agctaattga acagcaaatc ctaaacggtt
    11701 ttcttccctc cttcgcttat taactatttc taaatcccgt ttggaaaaag tgaagtaggt
    11761 ccccagtatc cattcatctt cagggatttg cataaaagcc tgtctctgtt ccggtgtaag
    11821 caattctcta cctctcgcaa ttttcattca gtatcattcc atttctgtat tttcaattta
    11881 ttagttcaat tatatatcaa tagagtgtac tctattgata caaatgtagt agactgataa
    11941 aatcatagtt aagagcgtct cataagactt gtctcaaaaa tgaggtgata ttttgcggaa
    12001 aatcggttat attcgtgtca gttcgactaa ccagaatcct tcaagacaat ttcagcagtt
    12061 gaacgagatc ggaatggata ttatatatga agagaaagtt tcaggagcaa caaaggatcg
    12121 cgagcaactt caaaaagtgt tagacgattt acaggaagat gacatcattt atgttacaga
    12181 cttaactcga atcactcgta gtacacaaga tctatttgaa ttaatcgata acatacgaga
    12241 taaaaaggca agtttaaaat cactaaaaga tacatggctt gatttatcag aagataatcc
    12301 atacagccaa ttcttaatta ctgtaatggc tggtgttaac caattagagc gagatcttat
    12361 tcggatgaga caacgtgaag ggattgaatt ggctaagaaa gaaggaaagt ttaaaggtcg
    12421 attaaagaag tatcataaaa atcacgcagg aatgaattat gcggtaaagc tatataaaga
    12481 aggaaatatg actgtaaatc aaatttgtga aattactaat gtatctaggg cttcattata
    12541 caggaaatta tcagaagtga ataattagcc attctgtatt ccgctaatgg gcaatatttt
    12601 taaagaagaa aaggaaacta taaaatatta acagcctcct agcgatgccg aaaagccctt
    12661 tgataaaaaa agaatcatca tcttaagaaa ttcttagtca tttattatgt aaatgcttat
    12721 aaattcggcc ctataatctg ataaattatt aagggcaaac ttatgtgaaa gggtgataac
    12781 tatgagcgat aaaatactta ttgtggatga tgaacatgaa attgccgatt tggttgaatt
    12841 atacttaaaa aacgagaatt atacggtttt caaatactat accgccaaag aagcattgga
    12901 atgtatagac aagtctgaga ttgaccttgc catattggac atcatgcttc ccggcacaag
    12961 cggccttact atctgtcaaa aaataaggga caagcacacc tatccgatta tcatgctgac
    13021 cgggaaagat acagaggtag ataaaattac agggttaaca atcggcgcgg atgattatat
    13081 aacgaagccc tttcgcccac tggagttaat tgctcgggta aaggcccagt tgcgccgata
    13141 caaaaaattc agtggagtaa aggagcagaa cgaaaatgtt atcgtccact ccggccttgt
    13201 cattaatgtt aacacccatg agtgttatct gaacgagaag cagttatccc ttactcccac
    13261 cgagttttca atactgcgaa tcctctgtga aaacaagggg aatgtggtta gctccgagct
    13321 gctatttcat gagatatggg gcgacgaata tttcagcaag agcaacaaca ccatcaccgt
    13381 gcatatccgg catttgcgcg aaaaaatgaa cgacaccatt gataatccga aatatataaa
    13441 aacggtatgg ggggttggtt ataaaattga aaaataaaaa aaacgactat tccaaactag
    13501 aacgaaaact ttacatgtat atcgttgcaa ttgttgtggt agcaattgta ttcgtgttgt
    13561 atattcgttc aatgatccga gggaaacttg gggattggat cttaagtatt ttggaaaaca
    13621 aatatgactt aaatcacctg gacgcgatga aattatatca atattccata cggaacaata
    13681 tagatatctt tatttatgtg gcgattgtca ttagtattct tattctatgt cgcgtcatgc
    13741 tttcaaaatt cgcaaaatac tttgacgaga taaataccgg cattgatgta cttattcaga
    13801 acgaagataa acaaattgag ctttctgcgg aaatggatgt tatggaacaa aagctcaaca
    13861 cattaaaacg gactctggaa aagcgagagc aggatgcaaa gctggccgaa caaagaaaaa
    13921 atgacgttgt tatgtacttg gcgcacgata ttaaaacgcc ccttacatcc attatcggtt
    13981 atttgagcct gcttgacgag gctccagaca tgccggtaga tcaaaaggca aagtatgtgc
    14041 atatcacgtt ggacaaagcg tatcgactcg aacagctaat cgacgagttt tttgagatta
    14101 cacggtataa cctacaaacg ataacgctaa caaaaacgca catagaccta tactatatgc
    14161 tggtgcagat gaccgatgaa ttttatcctc agctttccgc acatggaaaa caggcggtta
    14221 ttcacgcccc cgaggatctg accgtgtccg gcgaccctga taaactcgcg agagtcttta
    14281 acaacatttt gaaaaacgcc gctgcataca gtgaggataa cagcatcatt gacattaccg
    14341 cgggcctctc cggggatgtg gtgtcaatcg aattcaagaa cactggaagc atcccaaaag
    14401 ataagctagc tgccatattt gaaaagttct ataggctgga caatgctcgt tcttccgata
    14461 cgggtggcgc gggacttgga ttggcgattg caaaagaaat tattgttcag catggagggc
    14521 agatttacgc ggaaagcaat gataactata cgacgtttag ggtagagctt ccagcgatgc
    14581 cagacttggt tgataaaagg aggtcctaag agatgtatat aattttggct ctttgtcaaa
    14641 tgatgttggt aaagagaaat cttagaataa tggctctttg tcaataagga ctgatgggtt
    14701 gtacaaaatc aaatctgggt cagaatgaac ctcattctgg ctcagatttt ttgttatctt
    14761 actttgatta attgattgat caaaaagatt ctaattctca tgttctcaaa tgatttaaat
    14821 ccgtaggata ctcgtttcat tgtctttata tgggtattct tcgcttctat ttttccattg
    14881 gtgtaaggat agatcatcgc gttggtgatg ccttcttcat aggtcagaag gttttggagc
    14941 ttttcccgaa agccgtcatc taacgtttcg ggaagttctg ccaataagga gaaaaataag
    15001 tcagggtctt tgtctcgaaa ggcttcaact aattcatgaa aatagggata cgcctccttc
    15061 agggacgtag aaaagccaag caatcgatca atcatcatcg cttccgtaag aaatgggtat
    15121 tttggtgctc gaaaactttt ccatgttttg tattcataat ggttgatgtt tgcacgattt
    15181 tttagcaaaa agcgccagtt ctttttcagt ttttctgcct gacttttctg tcctacttta
    15241 cgaagttcat tcatttcacg gatacgcaac tcattaaagg cttgattcat gtgtttgata
    15301 atatgaaacc gatcaatcac tactttcgca tttggcagaa tacgtttggt aagctggaag
    15361 taggcggcgt tcatgtctgt gactaaaaat tttacttctt caggattagc gcagcctaag
    15421 aaatagcttg ttaatcgagg caatttacgc gtaggcaaga catcaattaa ttgtcctgtt
    15481 tcgccatctg cgcaaataaa gctcatttta tcttctatgg aagcgtgcga acgaaattca
    15541 tcaaccatca atactctggg gagaatcctc ttagattgct ttggtaagta gcttttaaac
    15601 tctttcaacg tacgaataac ggtggtcaaa gatacctgac aatttttcgc aataaaagat
    15661 aaagatactt tttcagtcag taaagaagca attttatatc tgacatgatt cgcgattgaa
    15721 tgtctgggtt gaacaaaata actttgagcc gtccaatggg ttcgacagtt tttacaggta
    15781 tagcgctgct tttttaagcg cataaccaaa ggcatgtgat tgtattgttc aaagcggaca
    15841 atcgtttcct tcttcccatt tttcactaca attactttcc cgtttccatc taccacagta
    15901 gaaccacaat ttctacaggt atggggagca ggtgagaaaa cagcatcgac gatcaacgtc
    15961 tttttcttct gaaaggtctc gtaagagacc tctgtaatca tcaaatcttt ctctattaat
    16021 cgcagcattt ttttgataga atcattcata tagcatatcg tcctctcagt tgtttatttt
    16081 gtcgtgattt aatcatacta gagaacgata tgttttttaa tacctaaaat aaaaatgggg
    16141 ctgaagaatc aattctgatt catcagtccc ataaattata gagccagaat aattggagat
    16201 caagtggatc agttcctctt gatctttttt agttgaaaat caatgcgttg ccatgacgaa
    16261 tcatgatgcg caatttgaaa ttataaaagc tacgaaagcc atatgcattt cgttttaaca
    16321 ctttgatatg gttgttcaga cattcaagtg ggccatttga ataactttgt tgtaaagcat
    16381 ttttgatttg tggcagaaat ttctggaacg ttctcaaggt cgtctgatag ccttcgggaa
    16441 gcatgatatt attggtaagt agttcttcaa acgatacgta gtctcgttcc tttacagcgt
    16501 aaagaaagtc ttgatataac tgatagccta cacgcaaagc agggctccct ttcagtaagc
    16561 gatccacaat atcggtctct gttaaatgag ctttgaagcc aggtcgccaa aggcgtcgag
    16621 tataatcaag cttgcgttca tctttttgaa gaagtttcca gtatcttttt aattgcttac
    16681 ctaattgata gtgtttttgt tctttgcttt ttaatagttg gttcgtttct ttgattcgat
    16741 gattgcgaaa ggtacgacca atatgttgga cgatgtgaaa ccggtcaata atcagctgtg
    16801 cttttggaaa cagcttttta acgagcgata cataaggagc gtacatatca atcacgatcc
    16861 attcgaccgc ttcacgaatt tctcgtgaaa aatgactaaa ataacgtttt aaaaaaggca
    16921 gttgtcggtt ctcgacaatg tccaataagc gctgtgtttg tccatccatc atgatgaaac
    16981 tcatagcacc tgaaacaccc cgaactgatt tgaattcatc aaaacaaagt accttaggta
    17041 acggtgtccg aaaaggattc aacggacgat aaaatcgctt cataatacgg taaacagaag
    17101 agaccgatag atttttctga gcggcgatct ctgtcattga ggtatttttt ttcagacgag
    17161 tcacgacaga ccagcggact ttctcactga tgaaacaatg ttttttcgca acagaagtat
    17221 ctgcgacaaa ggtccgctga caagctttgc atttgaagcg ttgctttttc aattcgaggt
    17281 aggtacggta ttcagaaaca tcgttcatta acaaccggac ggttgttgta ccccaacgca
    17341 caatatctga agcaatctgg tgtttacagt ggatgcattc ttgggctgta taaatcaagt
    17401 ttccacgata aatatgacag atttgccctt tgtatttttc ttttgtgaga caattttcgt
    17461 taaaagtaac tgataagtct agaatatcta atgtttcttt gataaggtga gtgtaagaca
    17521 tcttgattcc tccttttggg ttggttcgcc aaattaattc taaaggattt caaggtgtct
    17581 tttctatatg ttttggaaaa taaaaaagat gctggtgtca tccaccaaca tcaaaaagta
    17641 tagagccata attttttagg aaaatctcaa ggttatcttt actttttctt aggaaattaa
    17701 caatttaata ttaagaaacg gctcgttctt acacggtaga cttaataccg taagaacgag
    17761 ccgttttcgt tcttcagaga aagatttgac aagattacca ttggcatccc cgttttattt
    17821 ggtgcctttc acagaaaggg ttggtcttaa ttatgaataa catcggcatt actgtttatg
    17881 gatgtgagca ggatgaggca gatgcattcc atgctctttc gcctcgcttt ggcgttatgg
    17941 caacgataat taacgccaac gtgtcggaat ccaacgccaa atccgcgcct ttcaatcaat
    18001 gtatcagtgt gggacataaa tcagagattt ccgcctctat tcttcttgcg ctgaagagag
    18061 ccggtgtgaa atatatttct acccgaagca tcggctgcaa tcatatagat acaactgctg
    18121 ctaagagaat gggcatcact gtcgacaatg tggcgtactc gccggatagc gttgccgatt
    18181 atactatgat gctaattctt atggcagtac gcaacgtaaa atcgattgtg cgctctgtgg
    18241 aaaaacatga tttcaggttg gacagcgacc gtggcaaggt actcagcgac atgacagttg
    18301 gtgtggtggg aacgggccag ataggcaaag cggttattga gcggctgcga ggatttggat
    18361 gtaaagtgtt ggcttatagt cgcagccgaa gtatagaggt aaactatgta ccgtttgatg
    18421 agttgctgca aaatagcgat atcgttacgc ttcatgtgcc gctcaatacg gatacgcact
    18481 atattatcag ccacgaacaa atacagagaa tgaagcaagg agcatttctt atcaatactg
    18541 ggcgcggtcc acttgtagat acctatgagt tggttaaagc attagaaaac gggaaactgg
    18601 gcggtgccgc attggatgta ttggaaggag aggaagagtt tttctactct gattgcaccc
    18661 aaaaaccaat tgataatcaa tttttactta aacttcaaag aatgcctaac gtgataatca
    18721 caccgcatac ggcctattat accgagcaag cgttgcgtga taccgttgaa aaaaccatta
    18781 aaaactgttt ggattttgaa aggagacagg agcatgaata gaataaaagt tgcaatactg
    18841 tttgggggtt gctcagagga gcatgacgta tcggtaaaat ctgcaataga gatagccgct
    18901 aacattaata aagaaaaata cgagccgtta tacattggaa ttacgaaatc tggtgtatgg
    18961 aaaatgtgcg aaaaaccttg cgcggaatgg gaaaacgaca attgctattc agctgtactc
    19021 tcgccggata aaaaaatgca cggattactt gttaaaaaga accatgaata tgaaatcaac
    19081 catgttgatg tagcattttc agctttgcat ggcaagtcag gtgaagatgg atccatacaa
    19141 ggtctgtttg aattgtccgg tatccctttt gtaggctgcg atattcaaag ctcagcaatt
    19201 tgtatggaca aatcgttgac atacatcgtt gcgaaaaatg ctgggatagc tactcccgcc
    19261 ttttgggtta ttaataaaga tgataggccg gtggcagcta cgtttaccta tcctgttttt
    19321 gttaagccgg cgcgttcagg ctcatccttc ggtgtgaaaa aagtcaatag cgcggacgaa
    19381 ttggactacg caattgaatc ggcaagacaa tatgacagca aaatcttaat tgagcaggct
    19441 gtttcgggct gtgaggtcgg ttgtgcggta ttgggaaaca gtgccgcgtt agctgttggc
    19501 gaggtggacc aaatcaggct gcagtacgga atctttcgta ttcatcagga agtcgagccg
    19561 gaaaaaggct ctgaaaacgc agttataacc gttcccgcag acctttcagc agaggagcga
    19621 ggacggatac aggaaacggc aaaaaaaata tataaagcgc tcggctgtag aggtctagcc
    19681 cgtgtggata tgtttttaca agataacggc cgcattgtac tgaacgaagt caatactctg
    19741 cccggtttca cgtcatacag tcgttatccc cgtatgatgg ccgctgcagg tattgcactt
    19801 cccgaactga ttgaccgctt gatcgtatta gcgttaaagg ggtgataagc atggaaatag
    19861 gatttacttt tttagatgaa atagtacacg gtgttcgttg ggacgctaaa tatgccactt
    19921 gggataattt caccggaaaa ccggttgacg gttatgaagt aaatcgcatt gtagggacat
    19981 acgagttggc tgaatcgctt ttgaaggcaa aagaactggc tgctacccaa gggtacggat
    20041 tgcttctatg ggacggttac cgtcctaatc gtgctgtaaa ctgttttatg caatgggctg
    20101 cacagccgga aaataacctg acaaaggaaa gttattatcc caatattgac cgaactgaga
    20161 tgatttcaaa aggatacgtg gcttcaaaat caagccatag ccgcggcagt gccattgatc
    20221 ttacgcttta tcgattagac acgggtgagc ttgtaccaat ggggagccga tttgatttta
    20281 tggatgaacg ctctcatcat gcggcaaatg gaatatcatg caatgaagcg caaaatcgca
    20341 gacgtttgcg ctccatcatg gaaaacagtg ggtttgaagc atatagcctc gaatggtggc
    20401 actatgtatt aagagacgaa ccatacccca atagctattt tgatttcccc gttaaataaa
    20461 cttttaaccg ttgcacggac aaactatata agctaactct ttcggcagga aacccgacgt
    20521 atgtaactgg ttcttaggga atttatatat agtagatagt attgaagagg ttctgttgca
    20581 aagttttaaa taaagaataa aatcccttac ggtatctatg atttaagctg ggattcccaa
    20641 taataccttg atttcagtac agaccgaaaa cccgaagaga gtgccttctt ttcgggtttt
    20701 cttatataat cctcgaatgg cttccatgcc tttaatcgtg gtagaggcag tgcgtaaact
    20761 tcgatagaat ttattgcgtc tctttactgg acgatggtct tgttcaatca aattattcag
    20821 gtatttaatg gtacgatgtt ctgtcccttg ataaaagccg tattctttta gtttcttaaa
    20881 ggcacttgta atagaggggg ctttatctgt gactacaacc ttcggttcat caaactgctt
    20941 cactaaccgc ttaagaaaag cataggctgc ttgtgtgtcc cgttttttac gtaaccaaat
    21001 atccaaggtt aaaccatctg catcgatggc tcgatacaaa taatgccatt ttcctttaat
    21061 tttgatgtac gtttcatcca ttttccatga ataaaaggat tttttatttt tctttttcca
    21121 aatttgatag agtagtttgc catattcttg cacccaacga taaatcgtcg tatgagaaac
    21181 gttaatgcca cgatcatata agatttcttg aacttcacga tagctaaggt tataacgaag
    21241 atagtagccc acggctacaa taatcacatc ctgctgaaat tgctttcctt taaaatgatt
    21301 catcgtcatt cctcctgcta tctttttcta ttattctacc ttatttgata gtagatttaa
    21361 aactttgcaa cagaaccgag gagactgaaa atgaagaagt tgtttttttt attgttattg
    21421 ttattcttaa tatacttagg ttatgactac gttaatgaag cactgttttc tcaggaaaaa
    21481 gtcgaatttc aaaattatga tcaaaatccc aaagaacatt tagaaaatag tgggacttct
    21541 gaaaataccc aagagaaaac aattacagaa gaacaggttt atcaaggaaa tctgctatta
    21601 atcaatagta aatatcctgt tcgccaagaa agtgtgaagt cagatatcgt gaatttatct
    21661 aaacatgacg aattaataaa tggatacggg ttgcttgata gtaatattta tatgtcaaaa
    21721 gaaatagcac aaaaattttc agagatggtc aatgatgctg taaagggtgg cgttagtcat
    21781 tttattatta atagtggcta tcgagacttt gatgagcaaa gtgtgcttta ccaagaaatg
    21841 ggggctgagt atgccttacc agcaggttat agtgagcata attcaggttt atcactagat
    21901 gtaggatcaa gcttgacgaa aatggaacga gcccctgaag gaaagtggat agaagaaaat
    21961 gcttggaaat acgggttcat tttacgttat ccagaggaca aaacagagtt aacaggaatt
    22021 caatatgaac catggcatat tcgctatgtt ggtttaccac atagtgcgat tatgaaagaa
    22081 aagaatttcg ttctcgagga atatatggat tacctaaaag aagaaaaaac catttctgtt
    22141 agtgtaaatg gggaaaaata tgagatcttt tattatcctg ttactaaaaa taccaccatt
    22201 catgtgccga ctaatcttcg ttatgagata tcaggaaaca atatagacgg tgtaattgtg
    22261 acagtgtttc ccggatcaac acatactaat tcaaggaggt aaggatggcg gaatgaaacc
    22321 aacgaaatta atgaacagca ttattgtact agcacttttg gggtaacgtt agctttttaa
    22381 tttaaaaccc acgttaacta ggacattgct atactaatga tacaacttaa acaaaagaat
    22441 tagaggaaat tatattggga aaaatattat ctagaggatt gctagcttta tatttagtga
    22501 cactaatctg gttagtgtta ttcaaattac aatacaatat tttatcagta tttaattatc
    22561 atcaaagaag tcttaacttg actccattta ctgctactgg gaatttcaga gagatgatag
    22621 ataatgttat aatctttatt ccatttggct tgcttttgaa tgtcaatttt aaagaaatcg
    22681 gatttttacc taagtttgct tttgtactgg ttttaagtct tacttttgaa ataattcaat
    22741 ttatcttcgc tattggagcg acagacataa cagatgtaat tacaaatact gttggaggct
    22801 ttcttggact gaaattatat ggtttaagca ataagcatat gaatcaaaaa aaattagaca
    22861 gagttattat ttttgtaggt atacttttgc tcgtattatt gctcgtttac cgtacccatt
    22921 taagaataaa ttacgtgtaa gatgtctaaa tcaagcaatc tgatctttca tacacataaa
    22981 gatattgaat gaattggatt agatggaaaa cgggatgtgg ggaaactcgc ccgtaggtgt
    23041 gaagtgaggg gaaaaccggt gataaagtaa aaagcttacc taacactata gtaacaaaga
    23101 aagcccaatt atcaatttta gtgctgagga attggtctct ttaataaatt tccttaacgt
    23161 tgtaaatccg cattttcctg acggtacccc caaactaaga tttcatagat agattttctg
    23221 ataactttaa aaaacacgaa tagcggaaag gatgtcttca ttcgctaaag agtaataaac
    23281 tacttttcca tcttgacgtg attttgccat tccatgtttt tttaaaaaac gtaaatggtg
    23341 tgacgttgta gcgacactag cagtaagtat ttctgctaaa tcacagacgc acatttcctt
    23401 ataggtttct aaagcataga aaattttaat tctagaaaaa tcgctgaaac atttccctaa
    23461 cacaagtaag tttgaaaaat ctttttgatc caatttattt tttattccat ttactttttc
    23521 tttatgtacg acagtcactt ggcaaacttt tttcattcat ctcacctcac attcaaacga
    23581 ttatttgaat gaagtatacc tatttgatca ctcttttgtc aatctacctt aattccaata
    23641 cactattata agcaatttca tgtattgaag taaacttact tgcaagtgcg tttttgattc
    23701 caagttaaaa acatattatt attctacata atttcctaat caaataaaac tcctttgaaa
    23761 attgttctaa aggagtttta ttattttgta tttctactaa aaatagcgta caatgtaatt
    23821 actaagtaat tacgaaatgt aaaataatgg aggaaataat atgattacaa aaacaagaaa
    23881 acaaggaaat tctattatgt taacggtccc taaagaattc gatgtgccca atggtgttga
    23941 agtagaagct aagcttgtag agaatggtat cctttatgag tttgtagagc ctaaaaaaga
    24001 attttttgat tttagtgaag atattttggc tgatattctt tcagaaggtt atagcaaaca
    24061 agagatctta aaagaattta gaaatagaaa aaatgcgtta acttctgcat ttaaatctat
    24121 tgctgaagat actgttgcaa attctaaacc gatgacaaaa gaggagttgg cagcagaaat
    24181 tggcttatga gattctacct tctaaacacg taataaagta tctaaaaaaa ttaaaagaga
    24241 aaacattaaa agaacaattt ttaacgataa tttatgatga gatagcagtt cgtcctcatt
    24301 cgggagaaca aaaaacgggt gatttatcag gaatttgggc tattggattc aagtatgcag
    24361 gtacgacata tcgcgttgca tatgaaatta aagataatgc agtgatacct atcttactat
    24421 gtggaacgca tgaaaatttt tatgaacaat taaaaaagat taggtaagaa cccaatgttt
    24481 caacttgaga ggatagacga cactttaaaa gataattttt aacagctgag agttgtaata
    24541 ccctataatt ttaaaccact aacctatata tttatgaaaa atagaaaaaa ttaaaacgca
    24601 ttttaagcct ctttcaaatt aaaagcttca tccttatgca caaagagggc ttaaaatgcg
    24661 ttattttata ttgtttttta gtaataataa aaaaatcact ctaattctcc cataaatatt
    24721 atagattcct aaagattaaa atagattatt ccctattgtc ttttaagtag cggtagagtg
    24781 ttgccttgct aataccagtc atttccgtaa tttcttttac gctataaacc tgacttttat
    24841 acaattttac tgctcgatca acatctttct ggttcactcg tggacggcca cctttacgac
    24901 ctctcgcacg tgcacttttc aaaccttctt tggtacgttc aacaattaaa tcacgttcga
    24961 actgactaaa tgcttggaag acagtcatca ttaagcgtcc gtgaggcgtg ctggtatcga
    25021 agttttcttt caagctcacc agcttaacat ggtgttcttc aaaataggta acaaggtcaa
    25081 tcaaatcctt tgtactacga cccaatcgag aaaaactttc tacaattacc gtatctcccg
    25141 gacgaatttt atcttttaaa cgatttagtt ggggacgaac cgctttggtt cccgtcattt
    25201 tctcagttag gatttcatta caattttgtt cattgagtaa gtctaattga cgatttagtt
    25261 cttgtgaacg tgtactcact cgggcataac cataaatgta tccactcatg cttttcttcc
    25321 tttcgtactt taattctggc ttgattgtat cataaaaggg agttatagat acatagttaa
    25381 tgcaacaagt tatgatacaa aatatgacct cttttattta ataaaagagg tcatttcatt
    25441 ttgtctcata atcgattgtt tttgatacga gtgtgtatac gaaataaaca aaaaaatctt
    25501 aagtaaattt ctagatacct aatttaatcc taactagtgt atcctaaagt taataacgag
    25561 tttatcacaa tgaaaattat aaaatgctcc catattagat ataacatgca atatttgaat
    25621 tagaactaca aaatttattc gttttataaa gtaaataatg ttgagatact aaggaataga
    25681 atattataag gaattgagct gaatgtattg gataaaaaaa gaataacttt attagagatg
    25741 gactataaaa atgctcgtaa ttttcttctg aagtctgaaa gctatttgaa tgctcagcta
    25801 ccagaatata ttagttttga cgaaacttta aaatctgcta aaaaagtttt aacttcgccg
    25861 tttgtataat taagcgagac aaataaaaaa gccatttatg ttacactcaa attgtaatac
    25921 ccgctaaagc atacaaggag agtgaacata aatgacttat acccatctta caccaaacga
    25981 gcttgtaatg atagaagcat attttcatca agaaactccg gttgctatcg ttgcgaagca
    26041 gcttaaacgt ggacgccaaa caatttacaa tgtctataac tttctcaaat gtggtggaac
    26101 agcacttgaa tactttgaac aatacaaaga aaataagcga cgttgtggga gaaccgaaat
    26161 catttttcct gctgaggaaa aagaatacat tgaaaaaaga tcaactgaag gttggacccc
    26221 agacgtcatt attggccgtg cagagcgaac cttctcttgt tcaataagta ccctctatcg
    26281 ccggtttaag acgggagaat tcaatgtttt acatttaccg atgcaaggaa aacgaaaacc
    26341 aaatggttat aaggaaaaac gtggaaaaca ggcattcaaa agaaatattt ctgaacgtaa
    26401 aaaagattat gtcgttttcg aagaagaatt tggacattta gagggtgata cgattgtcgg
    26461 catccaccat aaaagtgccg tcatcacact cgttgagcga ctttcaaaag ccattatcgt
    26521 cttgaaacca gaaggccgta aggcagttga tattgaaaat tcgattaatg aatggcttca
    26581 atccgtaccc aaaaatcttt tcaaatcaat tacctttgat tgtggaaaag aattctctaa
    26641 ttggaaaagt attagtaata cgaatgatat tgatatttat ttcgcagacc caggaacgcc
    26701 ttcccaacgg ggattaaatg aacattcaaa cggactcctc cgaaaagatg gactaccaaa
    26761 agaaatggac ttcaaccaag tcaatcaagg attcatctca tccgttgcgt ccaaaagaaa
    26821 ccatatccct agaaaatcac taaattacca aacaccatta gaagtttttt tgagttacgt
    26881 aaatggaaag ttttgtctcg cttaatttga caaataatac ttcaaaaaaa aaccaaccga
    26941 aagatataaa agatattgta gatacacgaa tgtataaaga acgtgatgac ttaaactata
    27001 cgcttattat caataaagat ggaaactatt catggcgtcc tctcgttcta ctacatccta
    27061 ttctatatgt agatttggtt aattgtctca ctaaagaaga ccattgggag gagttaaaaa
    27121 agaggtttag tgaatttaac agaattaggc agaagtcgcc catcctctat aggtgggtga
    27181 tgaatgccgt tcggtatgag ggttaccgtt ggtaactcga agaccgacaa ctaaggcgta
    27241 ttgccttttt attttgttcc atgttacaat cagtctatac aagaaatgag ttgatataac
    27301 atggaattag atacaaataa tcattcagta tttcttcttt attaccacct tgttttagta
    27361 acgaaatatc gtagacaagt gattgatgat gaaatatctg attatgccaa aactactttt
    27421 gaaagaattt cagaatcgta tcacattact ttagtggagt ggaatcatga taaagaccac
    27481 gttcatatta tgttcaaagc tcaacctaaa acagaattga caaaattcat caatgcctat
    27541 aaaagtgcca gctcaagatt gataaaacgt gactttccaa gagtcaaaca atttctttgg
    27601 aaagaaatgt tctggtctaa aagtttttgt cttctgacaa ctggtggcgc accaattgat
    27661 gtgattaaga agtatatcca aaatcaagga aacaatcata aatagaaagt aggtgaactt
    27721 tatggaacaa ctaaaagcat acaaattcag aatctatcca acagaggaac aagaaatctt
    27781 ctttgccaaa tcttttggtt gtgtccgtaa ggtctacaat ctaatgcttg atgaccgaaa
    27841 aaaggcgtat gaagaagtta aaaatgattc ttctaaaaaa atgacttttc cgacaccagc
    27901 taaatacaag aaagaatttc cgtttttgaa agaaattgat agccttgctt tagccaatgc
    27961 ccaacttaat ttagataaag catacaagaa tttttttcgg gataaatccg ttggatttcc
    28021 acgtttcaaa agtaagaaaa atcctgttca gagttataca acgaataatc aaaatggtac
    28081 agttgctttg attgatagta aattcatcaa agttcctaaa ttgaagtcat tagtaagaat
    28141 taagcttcat agacaaccaa aagggattat caaatctgct acaatatcac gtcattctag
    28201 cggtaaatac tatatttctt tgttgtgtaa agaagaaatt atcgaattac ctaaaactaa
    28261 ttccacaatt ggtattgact taggtattat ggactttgcg attctttctg atggacaaaa
    28321 aattgataat aataaattca cgtccaaaat ggaaaagaaa ctaaagcgtg aacaacgcaa
    28381 attgtctagg cgtgctttat tggctaaaaa taaaggtacc aatctatttg aagctaaaaa
    28441 ttatcaaaaa caaaaacgca aagtagctag attgcatgaa aaagtaatga atcaacgtac
    28501 tgattttctg aataagttga gtacagaaat gatcaaaaat cacgatatta tctgtattga
    28561 agacttaaac acaaaaggta tgttgcgaaa tcataaatta gctaaaagta tttctgatgt
    28621 ttcttggtca aagtttgtga ctaaattaca atacaaggct gactggtatg gacgaaaaat
    28681 catcaaagta gataaatggt ttccgtctag tcagatttgt tcagagtgcg gacataaaga
    28741 tggcaagaaa tctcttgaaa ttcgagaatg gacttgtcct gtttgtcata ctcatcatga
    28801 tcgtgatatc aatgctagta tcaatattct gaccgaaggt ctaagactac attctatggg
    28861 attggcttag atccaatcat caagaaccgt aggaactacg gggatagctt ggtaaataag
    28921 agacaccgct gttagtaaag aaatacgcta tcaagtatgc tctattccca agaagctccc
    28981 acttcaagcg ttaagaaccg tcaggtttag ctaagtggtg agtagttcac aaaagataaa
    29041 aatattaact gttattctat acctgttgaa gcttccaaag gttcaaaaag gacagatctt
    29101 ggtgaaacaa tactaaactg gtgggaatat tttgaacaaa aaagcttagc tcagaatatt
    29161 aaataccaat attgcatgtt tactgacatc gctgattgtt atccatcaat ttatactcac
    29221 tctataacat gggccatgta tggtaaagaa aaagttaaaa atgatgaaaa taagtgttcg
    29281 ggctcacttg gcgataaaat agataaaaaa atatctggaa tgcaacacaa tcaaacaaat
    29341 ggtatccctc agggttccgt tcttatggat tttgtagcag agatcgttct agggtatgtt
    29401 gatttgagat tatcgaaaga attaaaaaaa ttagaaaatt taaaagatta caaagtactc
    29461 agatatagag atgattatag aatattttca aataatcgta atgatttgga acaaattatg
    29521 aaagtgttat cagaagtctt atatgattta aattttaagt taaattctag taaaacaaaa
    29581 ttatcagatg atattatcat agattctatc aaaaaagata agctctattg ggaagaaatt
    29641 aaggcaagta taagaatgaa tgccacaaac ttagatggtg atagagaaat tcgttatagt
    29701 ataaatttac aaaaacattt attggaaata aaaaagttag cagataagca tcctaattca
    29761 ggccaattga aaaaagcact ttctgagttt aataaagaac gcattattaa aatcacttca
    29821 aagccgaacg atcttttacc acttattggt atcctggtag atatcatgat aaataacccg
    29881 ggttctttgc cgcagtgtgt cttaattata gggcagttat taaatttcga aaatgagagt
    29941 aaggctagag aaatagttga aatgattata aacaaatatg ctttaaagcc aaatactgaa
    30001 tttatgatga tatggtttca aagattgacc accatttttg gagaaatgtt tgatagtgtt
    30061 ttatcatccg aatttgtatc taaaatcaaa gatcctgtct ctaatcagat gttttctgta
    30121 gactggctaa atgaagatgc taagaaatct ttttatgaag ggaccattaa agacgaagag
    30181 aaatatatta aaatgagtaa gaaaatatat attactgaat ttgatgattt taatgattat
    30241 cctttttaag tgaaaattta gaatgaatat aaaaaacatt acaatctaat ttttttaaaa
    30301 aaatgttata tcggaagtaa tctcttgatt tctatactat aagataagaa aaccactatt
    30361 taacaaggtt attcgaacct tattttaagt tacttattat ttaatgtatc gaaaaaggtg
    30421 aaataggttt gttataataa gaattaagta agacatgaat tgtctaagca aatgtagctt
    30481 atccatttca ttaaaataca tatggtgaaa aaacaagttc aaatagtaac taatttttta
    30541 aaaaactgat ttataaaaaa tacaacacga atgaggaaaa taaccaatga cagaacaaat
    30601 cgaaaaaaat tcaaaaagct tatatcaggc actgtggaat tccgcagata tcctgcgttc
    30661 aaaaatggac gctaatgaat acaagagcta tttactaggc ttggtctttt ataaatactt
    30721 atccgacaac atgctgcggt atgtctccgt tctattggag gaagaaacgg acgacctaaa
    30781 taaagcacaa gacctttacg ttgaagcatt taaagatgca gatataaagg atgatctctt
    30841 gtatgaacta aaagatgagt tttcatatac catcgcaccc gcattgacct ttaccgcgca
    30901 agtggcagcc attcatgatg gatcttttca attagaagac ctggtacaag gtttccgtga
    30961 cattgaacaa tccagcgaaa actttgagaa cttatttgaa gacattgatc tgtattctaa
    31021 aaaactgggg tcaaccccac aaaaacaaaa taaaaccatc gcagatgtta tgaaagaatt
    31081 agaagggtta aacatggcgg ggcatgctgg cgatgtctta ggcgatgcct atgagtactt
    31141 aattggccaa ttcgcatctg aatccggtaa aaaagccggt gaattctata ccccacaacc
    31201 ggtcgcaaaa ttgatgacac aaattgtttt acaaggaaaa gaagataaaa aaggcttttc
    31261 tgtttacgac gcgaccatgg gttcgggctc gttacttttg aacgctaaaa aatattccca
    31321 tcaaccggga accatttctt atttcggaca agagttgaat acgtctacct ataatttggc
    31381 gcgtatgatg gcgcgtatga acatgatttt gcatggggtt cccattgcca accaacactt
    31441 gcataatgcg gataccttgg atcaagactg gccaacagaa gagccaacga acttcgatgg
    31501 ggtgctcatg aacccaccgt attctgcaaa atggtcggct gataaaggct tcttagatga
    31561 cccacgcttc tctgcctatg gcgtattagc ccctaaatca aaagcggact ttgctttctt
    31621 attacatggc tactatcatt tgaaagatac gggcgtcatg gccattgttt tgccacatgg
    31681 ggtgctcttt agagggggcg cagaagggaa gatacgcaaa gccttgttag aaaatggtgc
    31741 cattgacacc gtcattggct tacctgctaa catcttcttt aatacgtcca ttcggttctg
    31801 ttgcaaagtt ttaaataaag aataaaatcc cttacggtat ctatgattta agctgggatt
    31861 cccaataata ccttgatttc agtacagacc gaaaacccga agagagtgcc ttcttttcgg
    31921 gttttcttat ataatcctcg aatggcttcc atgcctttaa tcgtggtaga ggcagtgcgt
    31981 aaacttcgat agaatttatt gcgtctcttt actggacgat ggtcttgttc aatcaaatta
    32041 ttcaggtatt taatggtacg atgttctgtc ccttgataaa agccgtattc ttttagtttc
    32101 ttaaaggcac ttgtaataga gggggcttta tctgtgacta caaccttcgg ttcatcaaac
    32161 tgcttcacta accgcttaag aaaagcatag gctgcttgtg tgtcccgttt tttacgtaac
    32221 caaatatcca aggttaaacc atctgcatcg atggctcgat acaaataatg ccattttcct
    32281 ttaattttga tgtacgtttc atccattttc catgaataaa aggatttttt atttttcttt
    32341 ttccaaattt gatagagtag tttgccatat tcttgcaccc aacgataaat cgtcgtatga
    32401 gaaacgttaa tgccacgatc atataagatt tcttgaactt cacgatagct aaggttataa
    32461 cgaagatagt agcccacggc tacaataatc acatcctgct gaaattgctt tcctttaaaa
    32521 tgattcatcg tcattcctcc tgctatcttt ttctattatt ctaccttatt tgatagtaga
    32581 tttaaaactt tgcaacagaa ccataaaagc tacgaaagcc atatgcattt cgttttaaca
    32641 ctttgatatg gttgttcaga cattcaagtg ggccatttga ataactttgt tgtaaagcat
    32701 ttttgatttg tggcagaaat ttctggaacg ttctcaaggt cgtctgatag ccttcgggaa
    32761 gcatgatatt attggtaagt agttcttcaa acgatacgta gtctcgttcc tttacagcgt
    32821 aaagaaagtc ttgatataac tgatagccta cacgcaaagc agggctccct ttcagtaagc
    32881 gatccacaat atcggtctct gttaaatgag ctttgaagcc aggtcgccaa aggcgtcgag
    32941 tataatcaag cttgcgttca tctttttgaa gaagtttcca gtatcttttt aattgcttac
    33001 ctaattgata gtgtttttgt tctttgcttt ttaatagttg gttcgtttct ttgattcgat
    33061 gattgcgaaa ggtacgacca atatgttgga cgatgtgaaa ccggtcaata atcagctgtg
    33121 cttttggaaa cagcttttta acgagcgata cataaggagc gtacatatca atcacgatcc
    33181 attcgaccgc ttcacgaatt tctcgtgaaa aatgactaaa ataacgtttt aaaaaaggca
    33241 gttgtcggtt ctcgacaatg tccaataagc gctgtgtttg tccatccatc atgatgaaac
    33301 tcatagcacc tgaaacaccc cgaactgatt tgaattcatc aaaacaaagt accttaggta
    33361 acggtgtccg aaaaggattc aacggacgat aaaatcgctt cataatacgg taaacagaag
    33421 agaccgatag atttttctga gcggcgatct ctgtcattga ggtatttttt ttcagacgag
    33481 tcacgacaga ccagcggact ttctcactga tgaaacaatg ttttttcgca acagaagtat
    33541 ctgcgacaaa ggtccgctga caagctttgc atttgaagcg ttgctttttc aattcgaggt
    33601 aggtacggta ttcagaaaca tcgttcatta acaaccggac ggttgttgta ccccaacgca
    33661 caatatctga agcaatctgg tgtttacagt ggatgcattc ttgggctgta taaatcaagt
    33721 ttccacgata aatatgacag atttgccctt tgtatttttc ttttgtgaga caattttcgt
    33781 taaaagtaac tgataagtct agaatatcta atgtttcttt gataaggtga gtgtaagaca
    33841 tcttgattcc tccttttggg ttggttcgcc aaattaattc taaaggattt caaggtgtct
    33901 tttctatatg ttttggaaaa taaaaaagat gctggtgtca tccaccaaca tcaaaaagta
    33961 tagagccgat aataaaagca gcatgatcaa ctatttgtca ttgaccatgc tgtctttttt
    34021 tattctatac acggtttgtc tcgtaacatt gtagtcttta gcaatcttag caatcgcaac
    34081 accattttta agatcttcaa cgatgctttt gtaaacaagg cgacgttggg gatcttttgc
    34141 gtctgcactg tataatttgg gccgcccttt gtagacgccg tttgcttttg cgatcttaat
    34201 tccttgtgcc tggcgacgtt tcgattcagt ccgttcttgt tcagcgatca tggccaaaat
    34261 ttggatgatc agatccttaa tgaatttatc caggagagga ttgccaattg cttcagccat
    34321 gatcggtaaa ctagtaatga tcagcttcac atttttcttc ttcaagtaat tgactgaagt
    34381 gatgatctcg tcataatttc ttccaagtcg atcaatagct tccacaataa aaatatcttg
    34441 atctcggacg taatctaatg cttcttggaa aacaggtcga tgagtaatcg ttgcgccaga
    34501 ttgtttctcg atgaaaattc tctctgcacc gaattttttc atttcttcaa tctggcgttg
    34561 ttcattttga tcgatcgatg agacacgtat gtatgcaact ctcaaaactt ttacctactt
    34621 tctgcaacta tttaaaatac accctaatca tacacgagga agccatattt ttcaatgtta
    34681 taccagtgtc tatttagggt aaaccttata tagacaaaaa ctaatgatgg aggaaatagt
    34741 atgtgtcact tttcttttta aatggcaata ttttttgtaa ataaatgtca atcaagaaaa
    34801 tttaaacgat tatgacatta aaaatatatt ttatgaattt tctagtatat aacttgattt
    34861 atctgttaag atttattaag aaaacgtttt cttatttttg atttcgaggt gatagacaat
    34921 gaaaaataag tttattttat ctttaggtat tttaactatt ggaattagtg taactggaac
    34981 tacaattcct acatttgctg atagtacaaa tgaaccaact actgtagtag ataataacca
    35041 agaattaact cctttagata ggaacggaat agccattggt aacccaacta acgacttaac
    35101 tgttactgaa aattatttaa tagtttctcc attacttgct cgagcagctt ctaaaacgat
    35161 acgagtgaca ggaacgatga tttttgataa agttggttgg ccttctagac ctcctcaatc
    35221 acggaattgg aaagaaaaaa gaaatggtta ttggtactat ggaaaattgt atttacaaag
    35281 ttataaatca gctggaaaca attggattgc gacttattca ggaaccttaa ctagaaagta
    35341 gggatttttt atgccagaat ttgtgaacac accaaatttt tatcaagata gcgatattct
    35401 aagtaaaatt aatttaccga aagaagaatc agctttacaa gttcagcgaa ctttacagga
    35461 gacacaaaaa attcaaaaat caatttctaa tctagaagat tctgaagaaa aaagaaaaaa
    35521 aagagaccaa aaaacatatc aaaaagaaaa ataatgattt taaaaaaaga gtgtctagtc
    35581 gacattcttt ttttctaatt gaaagtgttc ataaaatcac ccatttctgg acactttctt
    35641 tttttgcttt atttttcaaa aaaacaattc atttcatgtt cataaaccca taacaatatc
    35701 tatgttcagt taaactatat ggataaagtt atgttacaat aaaattaatg aaggagtgat
    35761 ttttttgaaa ataggatacg cccgggtatc tactggttta caaaatttgg atttacaaga
    35821 agacagccta aataaatttg gttgtgaaaa aatttttact gatcatatga gtggggcaaa
    35881 aagtaatcga ccaggattag aaatggccat tgattttgtt cgctctggcg atacacttgt
    35941 cgtttggcgc ttagatcgtt taggtagaaa tatggaagat ttgatttcaa tcgtcaatcg
    36001 actgaatgag cgtggtgtga gttttcatag tattcaagaa aatattacga tggacaaatc
    36061 aagttctaca ggacagctca tgtttcattt gtttgcggca tttgcagaat ttgagcgtaa
    36121 tttgatcctg gaacgatccg cagcaggacg agcagctgct cgtgcaagag gacggtttgg
    36181 tggtcgtcct gaaaaattgt ctgaacaaga tttggaatta ctgaagactt tagtggatag
    36241 cggtacacct attaagacta ttgcggaacg gtggaacgtc tcaagaacca ccatttatcg
    36301 ttatttggca aaaatggagg agaaaaatgg aaagacaaat tctcattagt ttttgtcatt
    36361 taatgctgaa aatttttgcc atttatctag aaaagtgaca atagtatgag aattttttgt
    36421 aagtgtctac tgataactta ttctcaaata tttagctatt tcttctttac aacatcgaac
    36481 atatgtttgt ataatgtgga agaatggagt gttatttatg atggattatt caaaagagcc
    36541 agtaaatgat tactttttaa tcgatatgaa aagcttttac gcaagtgtcg aatgtataga
    36601 aagaaattta gatccattaa caacagaact tgttgttatg agtcgatctg ataatactgg
    36661 ttcaggattg atattagctt cttctcctga agcaaaaaag cggtatggta ttacaaatgt
    36721 gagtagacca cgtgacttac cacaaccatt tcctaaaaca ctacacgttg ttccaccacg
    36781 tatgaaccta tatatcaagc gaaatatgca ggtaaataat attttcagaa gatatgtggc
    36841 tgatgaagat ctactgattt actcgatcga tgaatcgatt ttaaaagtga caaaatcact
    36901 gaatcttttt acgactgaag aaacacgaag tcagcgaagg aagaagctcg ctcaaatgat
    36961 ccaagaacgt attaaagaag agttaggttt gattgctacg gtaggcgtcg gcgataatcc
    37021 ccttttggct aaattagcct tagacaatga agcaaagcat aatgaaggat ttattgcgga
    37081 atggacgtac gaaaacgttc ctgagaaagt atggaatatt cccgaaatga cggacttttg
    37141 gggaattggt tcgcgaatga aaaaaaggct caaccaaatg ggaattttga gcattagaga
    37201 ccttgctaac tggaatcctt atacgattaa gaatagatta ggtgtgattg gattacagct
    37261 gtacttccat gctaatggga tcgatcgaac agatatagca atcccaccag aaccgacaaa
    37321 ggaaaaatca tatggaaatt cacaagtgtt accacgagat tatactagaa gaaatgaaat
    37381 cgagctggtg gtaaaagaaa tggcggaaca agtagcgata cgcattaggc agcataactg
    37441 taaaacaggt tgtgtccatt tacacattgg cacgtcgatc ttagaaacga gaccagggtt
    37501 ttcacaccag atgaagatcc ctatcacaga taatacaaag gaattgcaga attattgtct
    37561 tttcttgttt gataagtatt atgaaggaca agaagtaagg catgttggaa taacctatag
    37621 caagcttgtg tacaccgatt cgcttcagct ggatttattt agtgatccac aaaagcaaat
    37681 tgacgaagaa aatttagata aaattattga caagattcgg caaaaatatg gttttacgtc
    37741 gattgtacat gcttcttcaa tgttagaagg cgctagaagc attactagaa gcacacttgt
    37801 tggtggtcat gcgggcggaa atgggggaat taaaaatgat tgattacaat gatcgtggac
    37861 gtttaaagtg ggcagggttt tatttatctg atcatactga agaaattgat gccgacaatg
    37921 aacaacgaac cagtcaaaat ttagcaaaag aacaaatgac gactgaagag attgcggaag
    37981 tattgaacgc tgcagtcata aaaaatagat cagtatctat tcaaaaagaa gaacgaaacg
    38041 ctgaaggata ctatccagaa gatatcattg gcaagatctt aggtagtgat gagctgggga
    38101 tctacgttgg aaaagacaaa attcactacg acgaaatacg tcatatcgaa ttttaccagg
    38161 ataataaatg gagtcgatta gaatgaacat tatccagcaa tatgagctaa agtatataac
    38221 ctttgatcag ctatcagaag agatttgggg ttatggccaa cgtttgataa atgaggttgg
    38281 tgttgagcgc ttctctttct atgtagaagc tgcagcaggt tatcataatt ttaggtttta
    38341 tatcttcccg ttatatatat aaggtatttt acggattcta tagagttatc tctatgaatc
    38401 cttttttgtt tttacaaata ggagtagata ctagaataat gcgtgtgtta aactattatt
    38461 gcaaacgcaa taataaaaga aagtaggctt acgcaccatg tctatcaata catttgttta
    38521 ctcgcacccg atcaatgttt acattatcaa gaatttagga atcactgtag aacaattttg
    38581 tgagttatat gcctacccac aaggaacggt tgcaagctgg ataacccgac aacgtagaat
    38641 aaaatcatta cctgcttcat tcgtttatga tttaagcctg gcctctagtt taaacatgtc
    38701 tgatgtttat gaaaagctcc tgtctttaga aaaagaatat gattccttca agattaaaca
    38761 tgataaaaaa ataaaaaaac atatataata tcaatcacaa ttgtataata ttacgatatc
    38821 ttaatatcat gatatcgtaa tattgttttt ttctaagaaa atgcactata agaagggaat
    38881 tattagtaac aatatagaca gtttagtaat gtttaaatta ttctagttgc tgctcgcaaa
    38941 acatatttct tatcattaat aaaaaatttt aaagtaataa aaagtgatta ttttaatttc
    39001 gaataacata tgaataatct ttatatccga accgatatat atctttaaaa caaaataatc
    39061 acacaatatt acaatataat gcatatacga tattgcaata tcacaatatt atgatataat
    39121 tatattataa tataagatga atgggggata ttttaatggc aagaatattg tcagtagcca
    39181 atcaaaaagg tggagtttct aaaactacga ctagcgttaa tttagcagca tgtttgaaat
    39241 ttgtttacgg taaaaatgta cttttagtgg acattgatcc tcagggaaat gctacagata
    39301 atgtaggttt cgatatagat ggaacaaacc aacctacaat ttatgaagta ttaaaagggg
    39361 aggctgacat tacagatgct attctggact ataaaggaat tgatgttttg ccagccgaca
    39421 tagccctttc ttctgcagag agggaattta ctcaagtagg aagtgaacac aggcttaaaa
    39481 gagtacttca accaatcaag gacaactatg attatattat aattgattgt ccaccaagtt
    39541 taggaatgct tacagtcaac gcatttactg tttctgatga aattatcatt ccagttgaag
    39601 ctgcgtattt ctcattaaaa ggactaataa agttaagtga aactattgaa acggtaaaag
    39661 aatatacgaa cgacaagctt gaagtacgag gagttctatt tactaagtat aataagcgtt
    39721 ataacatttc taaagaaatg acgtctgcag caaccgaaat ttctagagtc attggtgcaa
    39781 aaattttcaa aacttatatt cgtaggacaa taaccgttga cgaagcgcaa gctgctggat
    39841 cagatctaat caattttaat aaaccctcaa cagctgaaga tgactataaa gcatttacag
    39901 aagaatattt aaaagaagtt ggtgattttg atggcagaag ataatcgcag tcaagctgca
    39961 gtaagtagat tactaggaaa taaaaataaa aagaatttta aatcaaaaga agtagaagaa
    40021 atcgaattaa ccaagaaaaa tataagtaaa gtcataaaag atcaaggaag tagtgtaaga
    40081 acagcagata gcattcgtat aaatccaatt ctaatgtcag cactcaaata ttggacgact
    40141 attgctgaat cagacaaaag taaaccagac gttatagaag atgcgctatt aaagtccata
    40201 cctgaagaat acttgattga aggatataaa ctagcaaaga aacaaaataa aatttaattt
    40261 acattcaata tcacgatatc ataatatcgt gatatttttt ttataaaaat cagtagtatc
    40321 aaagctgata agtcgcttat cttcatattg taatattacg atatcgtgat ataatattat
    40381 tgtaatatcg tgatatagtt actatgagct taaaccttga aatagagcgg tttgctttaa
    40441 tttatttttt aaggtaaact aaaaaaagat aaaaaaagac tactgcttta acaaagtttg
    40501 gcgacttatc agcagtagaa aaatatatag tggatagata tatttgttta attcattgta
    40561 acatagtttt gaacaaaacg ctatcctaca gaaagaggat tggct
//
