LOCUS       NZ_CP089164            20721 bp    DNA     circular CON 13-FEB-2024
DEFINITION  Staphylococcus aureus strain UNC_SaCF11 plasmid unnamed2, complete
            sequence.
ACCESSION   NZ_CP089164
VERSION     NZ_CP089164.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN23701156
            Assembly: GCF_021172925.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20721)
  AUTHORS   Wang,J., Franklin,T. and Wolfgang,M.
  TITLE     NIH Task A24 Option 3 - Murine Chronic Infection Model
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20721)
  AUTHORS   Wang,J., Franklin,T. and Wolfgang,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) Genetics, University of North Carolina at
            Chapel Hill, 120 Mason Farm Road 5000 D, Genetic Medicine Building
            CB#7264, Chapel Hill, NC 27599, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 27-JUL-2021
            Assembly Method                   :: Flye v. 2.8.3
            Assembly Name                     :: Sa11_genome_20210727
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 54x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/13/2024 04:35:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,923
            CDSs (total)                      :: 2,842
            Genes (coding)                    :: 2,752
            CDSs (with protein)               :: 2,752
            Genes (RNA)                       :: 81
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 90
            CDSs (without protein)            :: 90
            Pseudo Genes (ambiguous residues) :: 0 of 90
            Pseudo Genes (frameshifted)       :: 51 of 90
            Pseudo Genes (incomplete)         :: 41 of 90
            Pseudo Genes (internal stop)      :: 21 of 90
            Pseudo Genes (multiple problems)  :: 20 of 90
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP089164.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20721
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="UNC_SaCF11"
                     /isolation_source="sputum"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed2"
                     /geo_loc_name="USA: Boston, Massachusetts"
                     /collection_date="2018-07-11"
     gene            100..843
                     /locus_tag="LTK16_RS14470"
                     /old_locus_tag="LTK16_14470"
     CDS             100..843
                     /locus_tag="LTK16_RS14470"
                     /old_locus_tag="LTK16_14470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843758.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     gene            complement(1062..1247)
                     /locus_tag="LTK16_RS14475"
                     /old_locus_tag="LTK16_14475"
     CDS             complement(1062..1247)
                     /locus_tag="LTK16_RS14475"
                     /old_locus_tag="LTK16_14475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            1396..1467
                     /locus_tag="LTK16_RS14480"
                     /old_locus_tag="LTK16_14480"
     CDS             1396..1467
                     /locus_tag="LTK16_RS14480"
                     /old_locus_tag="LTK16_14480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(1706..2047)
                     /locus_tag="LTK16_RS14485"
                     /old_locus_tag="LTK16_14485"
     CDS             complement(1706..2047)
                     /locus_tag="LTK16_RS14485"
                     /old_locus_tag="LTK16_14485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(2134..2994)
                     /locus_tag="LTK16_RS14490"
                     /old_locus_tag="LTK16_14490"
     CDS             complement(2134..2994)
                     /locus_tag="LTK16_RS14490"
                     /old_locus_tag="LTK16_14490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            complement(3378..3914)
                     /locus_tag="LTK16_RS14495"
                     /old_locus_tag="LTK16_14495"
     CDS             complement(3378..3914)
                     /locus_tag="LTK16_RS14495"
                     /old_locus_tag="LTK16_14495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="WP_221554688.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDSYTL"
                     /name="recombinase"
     gene            complement(4008..4637)
                     /gene="mobV"
                     /locus_tag="LTK16_RS14500"
                     /old_locus_tag="LTK16_14500"
                     /pseudo=""
     CDS             complement(4008..4637)
                     /gene="mobV"
                     /locus_tag="LTK16_RS14500"
                     /old_locus_tag="LTK16_14500"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            complement(4875..5501)
                     /locus_tag="LTK16_RS14505"
                     /old_locus_tag="LTK16_14505"
     CDS             complement(4875..5501)
                     /locus_tag="LTK16_RS14505"
                     /old_locus_tag="LTK16_14505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(5513..5824)
                     /locus_tag="LTK16_RS14510"
                     /old_locus_tag="LTK16_14510"
     CDS             complement(5513..5824)
                     /locus_tag="LTK16_RS14510"
                     /old_locus_tag="LTK16_14510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            complement(5828..7762)
                     /locus_tag="LTK16_RS14515"
                     /old_locus_tag="LTK16_14515"
     CDS             complement(5828..7762)
                     /locus_tag="LTK16_RS14515"
                     /old_locus_tag="LTK16_14515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(7837..8130)
                     /locus_tag="LTK16_RS14520"
                     /old_locus_tag="LTK16_14520"
     CDS             complement(7837..8130)
                     /locus_tag="LTK16_RS14520"
                     /old_locus_tag="LTK16_14520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            complement(8544..9152)
                     /locus_tag="LTK16_RS14525"
                     /old_locus_tag="LTK16_14525"
     CDS             complement(8544..9152)
                     /locus_tag="LTK16_RS14525"
                     /old_locus_tag="LTK16_14525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001566953.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            complement(9521..10366)
                     /gene="blaZ"
                     /locus_tag="LTK16_RS14530"
                     /old_locus_tag="LTK16_14530"
     ARG             complement(9525..10366)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            10473..12230
                     /gene="blaR1"
                     /locus_tag="LTK16_RS14535"
                     /old_locus_tag="LTK16_14535"
     ARG             10474..12227
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.56"
                     /coverage="100.0"
     gene            12220..12600
                     /gene="blaI"
                     /locus_tag="LTK16_RS14540"
                     /old_locus_tag="LTK16_14540"
     ARG             12221..12597
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            12864..13457
                     /locus_tag="LTK16_RS14545"
                     /old_locus_tag="LTK16_14545"
     CDS             12864..13457
                     /locus_tag="LTK16_RS14545"
                     /old_locus_tag="LTK16_14545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            13429..14872
                     /locus_tag="LTK16_RS14550"
                     /old_locus_tag="LTK16_14550"
                     /pseudo=""
     CDS             13429..14872
                     /locus_tag="LTK16_RS14550"
                     /old_locus_tag="LTK16_14550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            14865..15680
                     /locus_tag="LTK16_RS14555"
                     /old_locus_tag="LTK16_14555"
     CDS             14865..15680
                     /locus_tag="LTK16_RS14555"
                     /old_locus_tag="LTK16_14555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(15800..16204)
                     /locus_tag="LTK16_RS14560"
                     /old_locus_tag="LTK16_14560"
     CDS             complement(15800..16204)
                     /locus_tag="LTK16_RS14560"
                     /old_locus_tag="LTK16_14560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_106669568.1"
                     /translation="MKEELYKIFMYVKTFYFQHTPFDDSYIEDIENYLLNYENNPHKSF
                     MKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKLLQKNYKTTLVDIK
                     GLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="hypothetical protein"
     gene            complement(16209..16775)
                     /locus_tag="LTK16_RS14565"
                     /old_locus_tag="LTK16_14565"
     CDS             complement(16209..16775)
                     /locus_tag="LTK16_RS14565"
                     /old_locus_tag="LTK16_14565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_049882581.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKKIKKIGCYTKRFRYI"
                     /name="DUF4062 domain-containing protein"
     gene            complement(16987..17079)
                     /locus_tag="LTK16_RS14570"
                     /old_locus_tag="LTK16_14570"
     CDS             complement(16987..17079)
                     /locus_tag="LTK16_RS14570"
                     /old_locus_tag="LTK16_14570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(17248..17595)
                     /locus_tag="LTK16_RS14575"
                     /old_locus_tag="LTK16_14575"
     CDS             complement(17248..17595)
                     /locus_tag="LTK16_RS14575"
                     /old_locus_tag="LTK16_14575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(17614..18231)
                     /gene="cadD"
                     /locus_tag="LTK16_RS14580"
                     /old_locus_tag="LTK16_14580"
     ARG             complement(17618..18231)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            complement(19441..>19723)
                     /locus_tag="LTK16_RS14585"
                     /old_locus_tag="LTK16_14585"
                     /pseudo=""
     CDS             complement(19441..>19723)
                     /locus_tag="LTK16_RS14585"
                     /old_locus_tag="LTK16_14585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(19734..20410)
                     /locus_tag="LTK16_RS14590"
                     /old_locus_tag="LTK16_14590"
                     /pseudo=""
     CDS             complement(19734..20410)
                     /locus_tag="LTK16_RS14590"
                     /old_locus_tag="LTK16_14590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     ARG             complement(9522..10366)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             2837..13130
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(19237..19384)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          101..843
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(2135..2994)
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(4363..4637)
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 gaatttatat ttttatttgt cgattacttt attattaatc gttataagct tataatattt
       61 tactaagggt ttataaacat tttataaagg gttgatgata tgaaaagtgt aaaaaggttg
      121 agtgaagaat taggggttag taagcaaacg atttttaata atattaagag attgaatata
      181 gagacaataa aacaggaaaa cacttcgttt attaaagaag ataccgatat agaaaaaatc
      241 attcaaagag taaatgaaaa taaaaagaaa tatggttttg aaagtgctac tgaagacaaa
      301 caaaaaaaag agtcggataa tattaatttt gaatctaaaa gcgatgctca aatagtagaa
      361 atacttaaaa atcagattaa tactttaaat aatcaaattg aaaaacaaga aagtcgtcat
      421 gaaacaacaa ttgaatttta cagaaaagag ttgcaagaaa gatcaaaatt gcttgagaat
      481 cagcaagttc tggcattaga gagtaataaa aagattcaaa aattagaaaa tcaattagaa
      541 aaagaaaaac accttaatta tccctttgat acatctacta acgctagaca aaacgttgat
      601 gcacaagaaa aaacatatac tactagtcct gtaaatatta accgagatca ggaagaaact
      661 aaagaaacag agattcaata taaggatata tctggaagtc aaagcgacga aagtacacaa
      721 ggtgaagaag cacaaagaga agacgtttca gctaatccaa atgacaatga tagtgatata
      781 gaagaaaaga gtgaagaaac ggaacctaaa aaggggtttt ggagtcgtct atttggtaac
      841 taattttaat taaaaaggta cgacaagttc ataaattagc cgtgcttttt tatgtgaatt
      901 gaacttctga taatcatcga ttatgttaac caaacaaaaa gccataaatg cctatatgac
      961 ggcatttatg gctttttact ttcattatct tttatgcatc ttttatacat cgttgatttg
     1021 acgcgttttc attcttttgc attggcaagt attttgtatc tttattcagt tactatttct
     1081 tttctccaac ctaacaaacc atctttaact ctaataatat gtttgccacg ccagacactt
     1141 cttacttcga aataatacca ttccccgttt ttgttgagga aataaatatc ttgataacct
     1201 tctttaatga catattttgt agcttcttgt ctttgatcgc caaacattat caatcccacc
     1261 cttatattta tttatcttta atatataaca acatttatta atattcatgt tatttcatgg
     1321 aaggagagat ttgttataat gtgaaggtcg tctatctctc agatgtcaat tcggcgtaga
     1381 gaggaggtgc gatttatgaa tgaaattctt gttcacatca tgacaacggc aatcagtggt
     1441 tgtctcgtta cgttatttgg ttattagctc cataaacgtg ataaaaaata atatagacga
     1501 ttaaagccaa ttcaccaaaa aaccccgaac tacggcgaat agttcggggt tttgtgcgtt
     1561 tacaaacgaa attcttgtta cttttagtat atatttcata ttgccttttg taaactcttc
     1621 tattcttatc aatacatttc aaggtgtcgt aaaaatactt tcctttttca tattgcctga
     1681 tgtgcattaa attttgattt taaaatcaac ccatgaacga atgaatggcc caaactaaaa
     1741 atccggcaac aggaaagaaa agccaccaaa aatcataaag aaaatcaact atggaaggta
     1801 ccctgttact ctctctataa tttccctcta aaataacttt tttaaaacgt gcatctcctt
     1861 taattaaatg ctctaaagag attccgaata aatcgctcat agcaatcaaa atatctaagg
     1921 aaggatagtt tttggcactt tcccatttag aaacactttg tctggaaacc tttaatatat
     1981 tggctaattc ctcttgagac catcctttta attctctctg ttcttttata gcttcagcta
     2041 atttcataaa atcactcctt aactcaaact ataattaaaa taattgaaaa gtcacgatac
     2101 ttttagttaa ccaactcgca acgaaaagtt gcgttattcc caattcagtt caagttgttt
     2161 taaaaaatcc tctcgttctt tctctaattg tgggtcgtaa tctttttgag gttgcttttc
     2221 atatgaccgt tcttctaacc atttaggcgt cttttcacgc ctcacatatt gtcttgattt
     2281 atctatcttg gacatttgag gttgtcgttt gttatgaatg cgtttctcag cgtcaaatgt
     2341 gaactctatc cattcaattt tacgcccttt tttcgctttg attttattga tagtaagatt
     2401 attaaatata gaacctaatt caataataat aggtttaaaa acatttttgt taatatcagt
     2461 catacgataa gatttaggta tatctaaacg atttttaaaa tcatcgatgt gaatttttaa
     2521 atagcctgta tgtttgtatt gtttaagtaa tctaaacata tttttagaat atgtagattt
     2581 aagcctagtc atttctttta attcaaattt tgtaaaatta ttagtaattg aattcaatat
     2641 gtgttttaaa tttgaagaag ttgatatttc tagatattgt tctcgcttat ggattctata
     2701 atgattgaat aaaacgaatc tttctattac atcatcatct tcatatctaa tggttaaatt
     2761 caacatcttt ttatacacat tatctaaatc attagcaaat ctattaatat tacgtgtttc
     2821 tggactataa ttacttaatt tttttaattc atcaaaagac aaacgtaatg tattagtatc
     2881 ttgctctttt aatttattac acatcgcaaa aaataaatta atttcagtag ctgtaaatcg
     2941 ccttaatgga actaaattca tttcattttt atatacaact gtctctcctg tcatgataca
     3001 gcccccttta ttacgaacct aaaggagtat cgtttgaata tacactccca tttgaaaact
     3061 tttattcaca ataaactact ttattatcaa tgtcaaacca taaaaggagt acaacttttt
     3121 aaaacactcc ttttatgtgg caaaaacact ccttttatgt ggcaaaaaca ctccttttat
     3181 gtggcaaaaa cactcctttt atgtggcaaa aacactcctt taggcattga aatcccttgt
     3241 tgctctaggg ctgaacaagc ccctaaaaag gtttttaaaa agatttataa aaatatatta
     3301 aaaagttcga ggggggctac ctatttttca tcctaaaaaa taattaacct caaacaaatg
     3361 catttaaata tctattttta taatgtataa ctatcttctt taaaaatgat ttctcgttct
     3421 tgtgcttgat atttcttctt aaagaactgt tcatcattgt tatctatcgt cattacttca
     3481 cgtattttag aattgtctaa atgattatca atatgattta ttagtgtatg ataacgctct
     3541 tctttcatca tacttttaat gattttaaaa acttgattga ataacttaag cgtataattt
     3601 agttctttat ctttcttttc attctctgac aacaaataat tataacgttg tgctaaatca
     3661 ttaaattctt caaccagctt ttcattttcc atatggacac tagtcaattc attaactaaa
     3721 ctttcatttt gtttctctgc tttttttaat gacttcccac ttttaataca ttcataatca
     3781 tctaatatca tctgtgctgc tttaatttgt ttagtgtatt tttcaaaatc agttttagta
     3841 attacaatat tgcctgtttc ttgcttctct ttatgaaacc atccacctac atttttagtt
     3901 ttaatttcat acatgacact cagaagcttt ttaagcgtat ctaatgattt ttggtagttt
     3961 tgtatcaatt tatcattttc ttgctttaaa taatcctcta tttgcttcta gcgcatatgc
     4021 atttgtttat gatattctgt tttttgttta taacggctaa cttgatcatg tttttctttt
     4081 gtaagttgtc tagaaattcc tcgttttaaa tcatagcctt gcttattaat atacgtattg
     4141 aatctatctt ggaattcggt taatgctttt ttattaccta caacttcttt cgcacttaaa
     4201 cgtccatctt tagtaatagg aactacgcca taatgcatat gtggtgttat ctcatccata
     4261 tgtactgtcg catataaaag attttcttta ccgtattctt cttccaagaa cgctttagca
     4321 tgcttaaaaa actattttgt ctcttcttca gataattgat taaaaaacac attatctgat
     4381 gtaattaatc catcaatatg tttaatggca tctgttctaa ttttgcgttt ccctttataa
     4441 tttttttcga ttttctcatc aattttttta ttaaaatcaa acttagtatc attgactaaa
     4501 tcatagttta aatatgactt acttaaatca atatctatat tttcataatt tttattttct
     4561 ctttgaatat gtctttgaat acctcttgta tttgtttttg atttcacttt aacaactcga
     4621 ataattgaat aagacataat aaatcaactt ccactgcata tgattataac acctaaacac
     4681 agaaaagttt taacatacta gacttattaa aaaccaaata agtcattaaa aacgtgtgct
     4741 ctgcgaggct tgttttttgt catcataaaa aaggactgga aaatccagtc cttaaattaa
     4801 aaaactcaaa agtaatgact aatcatattt catattgttt tttctctatg tatggctata
     4861 cctatcaata tttcttaact tctaagctca gaaatattga ctatgacatc aaatcgtttc
     4921 gcaagctcta aatcatgcgt tacgacaatc atagttttat tttcatcaag tagcttcaat
     4981 aataaatcaa taactatttt tccatttttc gtatctagtg acccagtagg ttcatcagct
     5041 aaaatgattt tcggatcttt taatattaat cttgccaatg ctactctttg ttgttcacca
     5101 ccgcttagag aactaacaat tctcttgata tctaaatcta ggccgacctt ttttaatact
     5161 tctttcttta agttcatatt atctttttta ttctttttga actttagggc taaatctaaa
     5221 ttttgactga ttgtttgatt ttcaagtaaa gcaaaatttt gaaacaaata ccctaacgta
     5281 tatctataaa aatcgacttt cttttttagt aacttatctt caatatatat gcttccttgt
     5341 gatacatctt cgaacccagc gattatgtta agtaaagtag attttccagc gccactttct
     5401 ccaactaaag catatgattt tcctttttca aaattaaagt tacatccgtc taaaatgttt
     5461 ttattacctt tttttacaaa aacattttca agttttatca ctatcggtca cctcatttta
     5521 aaaagctagg aatatctttt gtaatgtatt ctatcgaacg cacatatttc cctttatgat
     5581 ttactttcac atattctttt gtaggatcat aacctaaaaa atccaattta taactctttt
     5641 tttctccatt tttagagtat acagttatat ttctatagtc ctgggtatct tttggaactt
     5701 tggcataaga tactttttct tttaacagtg ggttaaaacg atctaaatgc tcatttctaa
     5761 ccaataacag actaagtatg atgattaata gtacaattgt tacaataatt aaagttcttt
     5821 tcattgttta aatctccctc attaaatctt taaagtattt ttcaagatat ttaatataag
     5881 caatttgaag taaatgttga ataatagcaa tagacattat tatgaatagt aatatctttg
     5941 aaccaaataa aatatgcgta gtgtaagcta acataataga aagtaagata gaaattgtta
     6001 aataacgtac attactgctg aataatgaat aaccatgaat ttttcttaat aatagttgct
     6061 ttttattcca gctaaaatat tgaattgttt caaatacagt agctatcaaa agaatgaaaa
     6121 cgttaataat aatagtaact attgttatta tcatttttgt tttcgtttca tttaattcat
     6181 ttaacacaga atccttgtaa ttagttatac cgctaatttc ttcttctagg tgattatctt
     6241 taagcaactg tttaagtgta tctaaatctt taaatagata tccaccttga gaaacagcag
     6301 ctaaataaaa atctcctgtt aaatcgtcaa gtgtcaacaa cattactatt ggagaatcta
     6361 gatacccaaa tttcaaatta gttgtgcgat caaaagaaaa aacagatacg ttttttgaca
     6421 gtacttgcac atctactttt ttgttttgtt gcttttgaaa gtcaatccat ccttggtgat
     6481 ttttttgaat ttcagatttt tgatattgta accttggagg aataaacacg tttattttat
     6541 ccgaatgatt gtcaatcatt ttaaaatcat gatttatatt tttatagaaa ttcagaaaat
     6601 tgttattgat aaaaaagaca ttgccatttt caggaatgta attgttttta tcgggattgg
     6661 ctatattatt attctttaaa agcaatccac caagttgttc gcttttctta attaaattgt
     6721 atatattagt ttctaaaatt tgtttttctt ctgaatttct aatattagga gaaatctcta
     6781 atgtatagta attatctaac ttttgccaga ttttttcaga gtcatatata ttctttaact
     6841 tcgtataagc atttaaattt tgtgccagta aaaaagatag tattagcacc atgatacatt
     6901 tggtgaaggt acccataaat attgaaaact tatatccttt tttccctttt aagattaatg
     6961 gaatacttaa cttcaaaaga agactatacg aaatcagcca cagcaatgta gtaatacaag
     7021 caaaaacaaa aagcaacacg ataaatctac gaataaacat taagaaatcc aattctaaat
     7081 tggctatatg aatgattaat atattagcaa taaagaaaat agcggtaagt actagccaat
     7141 aaatgatttt tatatgaata ttatgaaaaa taatgcgtgt agttgaaaag ccatgtagct
     7201 tttgaatagc ataaaatttc aaattatatc ctctgtcata taagaagtac aaaagatata
     7261 atacgcctaa gaatatgaaa ggcactaata aatcattatc tatgactaat tcaaaaaata
     7321 atatgtttct atttatgtat tcaacttcag atgttaaacc agcttttttt aattcactcg
     7381 taagctcttc tacattgaaa tgttcaccaa taatataata ctttcctttt atctctctgt
     7441 ttaataaatc tgatggagtt aaaagtgatg ttttattacg tataaagtca gaattatttc
     7501 gttttgagtt gaaaacaaaa aattcttttt tattatcaaa atctttaacg gatttaatta
     7561 tttgtatatt ttgatttttg gcgcctgatt caatgacatc taacactttt gatttactgt
     7621 tagatttatc ccaattagag attgttaaaa tattggaact ttcaggtata atttcttcat
     7681 tttctttgaa gaaaaataaa aataatagcc ctgaaattaa taataaagta ctaaaatcta
     7741 aaaataattt gaattttttc atattgcctc tttcaagaga atagacagaa ttaagtttac
     7801 ttaattctgt ctattctcct taattaatat atgtaattag tgaagactat aaaatgtttt
     7861 gtttccaccc caagcctttg gagcagatgc cttagattga acaccaggtc gagcaacacc
     7921 actaaaagat gaatatttcc ctactgctgt tgaaccatga tttcttttat tgtgactata
     7981 ataagaccat acgtaatgtt ttccaatacc atggctccaa acaccaccag ctacatgtac
     8041 tgttgcagct tcagctttat aagttacacc taataaagtg ccgaataaga ttgtactagc
     8101 aatacaacta gaaacaaatt tctttttcat aaaaacacct ccatttaata ttctttattt
     8161 attatagcaa aaataaataa aatagagaat gagtaaaaat aatctaaaag tgttttttct
     8221 gctctgttgc ttgttttgtt catctatata taatattaat tctattatcc ttaaattaac
     8281 tatcattaaa caacgatatg acaatgtata ataaatacaa tttcactacc tataattcaa
     8341 cattatataa actaaagtat ttcaaataat taactgtatt aatactctca tcatgattgc
     8401 gttataaaca ttcgttaatg agaaaaagag agagcatatt tacgctctct tttcttgtct
     8461 tattattaaa aactcataat agattataat catctgtttt gagacgctgt gagaagctct
     8521 cagttgcatt gaaacaaagt ttattaaatc aaatcattat cgtttttaat tctgtaaatc
     8581 gtctgccttg ttatatttac ttctttcgca attttactaa ttgattggcc ttcttctaac
     8641 atttctacaa cgcgatgata aataatacgt ttctgtggat ctttagcatt tggtgaataa
     8701 agtaaggggc gccctttata tacgcctttt tccttcgcaa cttgaattcc ttgcgcttgt
     8761 cgacgtttac tttcatttct ctcttgttct gaaaccattg ctaatatttg aataattaaa
     8821 tctttcataa acttatccag taatggattg ccaaccactt cattcatcat aggtaagcta
     8881 gtaatcatta attgtacttc tttgtctttt aaataattaa cggtatgaat cacttcatca
     8941 taattacgac ctaaacaatc aatggattct actacaaacc gatctcccat cctcaaaaag
     9001 ttaagtgctt cttgaagtac tggtctattt tcaatagatt tcccagactg tttttctgta
     9061 aatatttttt cagcacaaaa cgtctttaaa ttttcaagtt gtctttctaa attttgatcg
     9121 ttcgatgata ctctcgcata gccaacaatc attgatttcc atctcataat taatatacac
     9181 cctaatcata cgtttcagtt actataaatt caacaattat gtcactttgc ttgatatatg
     9241 agaattattt aaccttataa atgagaaaaa agcaacgcac tttaaataag atacgttgct
     9301 ttttcgattg atgaacacct ataattaaac tattcatcta ttatttatga ttttttgtat
     9361 atacaatatt tctagtttgt taaagagaat taagaaaata aatctcgaaa ataataaagg
     9421 gaaaatcagg ttttgatatc aaaattatac atgtcaacga taatagaaaa tataatacaa
     9481 actataagat gttatcagta tttattatgc atttagaata ttaaaattcc ttcattacac
     9541 tcttggcggt ttcacttatc aacttatcat ttggcttatc acttttattg tctttattcg
     9601 taaaaatgac taaaacaata ggttcagatt ggcccttagg ataaacaaaa gcaacatcat
     9661 ttctagaagc atatgttatt gcttgaccac ttttatcagc aaccttatag tcttttggaa
     9721 caccatcttt aattaaagtg tctccgtttt tattattaaa cattaaatca agtaagaaat
     9781 ttttattttt tttgcttaat tttccatttg cgataagttt atttaaagtc ttgccgaaag
     9841 cagcaggcgt tgaagtatct tttttgctct ttggcgaata gtaatttaat tctatctcat
     9901 atctaactgg atttgttact ttatctccta gttcttttag acgttgttta acttttttga
     9961 ttccaccgat ttcttttata attttattgt ttgctgtatt atcactatat gtcattgaag
    10021 cctcaataag ttcttttaaa gtgatgtctt ttcctacata tttttctaaa ataggagaat
    10081 aagcaactat atcatctttg ttaatatgta cttttttatt taacttatta taaggtactt
    10141 gttctaacaa aatagcacta tttatcgctt ttgaagtcga agcataggca aatctcttat
    10201 ctgaattaaa ttttacttcc ttaccacttt tagtatctaa agcataaaca ccaatatgag
    10261 cattatattt tttttctaaa tcatttaact ctttggcatg tgaactgttt gaattacatg
    10321 cacttaaaac taaagccatt acaattaaaa atattaactt tttcaaaata aaccctccga
    10381 tattacagtt gtaattttta caaaacaata atattacaat tgtaatattg atgtcaattg
    10441 tttattataa atatttgaaa gaaggtgtca aaatggctaa attactaata atgagtgtag
    10501 taagcttttg ttttatattt ctattgttag tattttttag gtacatatta aaacgctatt
    10561 ttaattatag tttaaattat aaagtttggt atctaactgt gcttgctgga ttaattcctt
    10621 ttatcccaat taaattctct tttataaaat ttaataatgt gaataatcaa gcgcccacag
    10681 ttgaaagtaa gtcacacgac ttgaaccata acataattac caccaaacct gttcaagagt
    10741 tcgcaacaga tatccataag tttaattggg attcaattga taatatctgc acagttattt
    10801 ggatagtttt agttattatt ttaagtttta aatttttgaa agccttatta tatcttaaat
    10861 atttaaagaa acagtcactt tatctaaacg aaaatgaaaa aaataaaata gatacgatac
    10921 ttttcaacca tcaatataaa aaaaatattg tgattcgaaa agcagaggct attcaatctc
    10981 caataacttt ttggtatggg aaatatatta ttttgattcc tagttcatat tttaaaagtg
    11041 taattgataa aagactaaaa tatataatac tgcatgaata tgctcatgct aaaaatagag
    11101 atactttaca tttaattatc tttaatatct tctctattat tatgagttac aatccattag
    11161 tacatattgt aaaaagaaag ataattcatg acaatgaagt agaagccgat agatttgtcc
    11221 ttaataatat taacaaaaat gaatttaaaa cttatgcgga atctattatg gactccgtat
    11281 taaaaacctc atttttcaac aaaaatatat taagccattc atttaatggt aaaaaatcat
    11341 tactcaaaaa tagattaatt aatataaaag aagccgatct gaaaaagcag tcaaaattaa
    11401 ttctaatttt tatttgtatt tttacttttt ttatcatgat aattcaaagc cagtttttaa
    11461 tggggcaatc cttaactgat tataattata aaaagccctt acaaagcgat taccaaattt
    11521 tagatgaaag taaaaatttt ggttcaaata gtggatcttt cgttatgtac agcatgaaga
    11581 aagacaaata ctatatttat aatgaaaaag aaagtagaaa aagatattct cctgattcaa
    11641 cttacaaaat ttatttagca ctgtttggac ttgaccgtca tattataagt gataaaaatt
    11701 cacgtatgtc atggaatcat aaacattatc ttttcgagtc ttggaataag gaacaagatt
    11761 taaatacagc aatgcaaaat tcagttaatt ggtacttcga acgtattagt aatcaaatac
    11821 caaagaacta tactgcggct caactcaagc aattaaatta tggtaatgaa aatttgggaa
    11881 gttataaaag ctattggatg gaagatagtt tgaaaatatc taatcttgaa caagtaatag
    11941 tttttaaaaa tatgatggaa caaaataacc attttagtaa aaaagcaaag aatcaattat
    12001 cttcttcatt attgattaag aaaaatgaaa agtatgaact gtatgggaaa acaggtacag
    12061 gtatagtaaa cgggaagtat aataatgggt ggtttgtagg ttacgtaatt acaaatcatg
    12121 ataagtatta ttttgctaca catttatcag atggaaaccc gtctgggaaa aatgctgaat
    12181 taataagtga aaaaatatta aaaggaatgg gtgttttaaa tggccaataa gcaagttgaa
    12241 atatctatgg ctgaatggga tgttatgaat ataatatggg ataaaaaatc agtatcagct
    12301 aatgaaattg tagttgaaat tcaaaaatat aaagaagtta gtgataaaac gattagaaca
    12361 ttaatcacaa gactatataa aaaagagatt ataaaacgat acaaatcaga aaatatttat
    12421 ttttactcat caaatattaa agaagacgat attaaaatga aaactgctaa aacctttctt
    12481 aataaactgt atggagggga tatgaaaagt ttagtgttga attttgcgaa aaatgaagaa
    12541 ttaaataaca aagaaattga agaattgcga gatattttaa atgatattag taaaaagtaa
    12601 ttagaggtat gtttcaaaca taatacatat gtaaactatg cttgactctt attaaattag
    12661 ttttgttaat gacatttaaa atatattatt aaagatgaga gtgtacagaa aataaccatt
    12721 ttctgtacac tcttctttta tgtctaaata agtaagaatt acataggatt atgtgttcaa
    12781 aaacccaaca aaaaatctat gttcataaaa gaccttgtaa ttaagttatg gtacactgaa
    12841 gatgtatata ggaggtttgt attttgaaaa taggttatgc aagagtttca actggattac
    12901 aaaatttaaa tttacaggag gatcgattaa atacatatgg ttgtgaaaag atatttaatg
    12961 accatatgag tggttcaaaa agtaaaagac ctggtttaga taaagcaatt gaatttgcga
    13021 ggtcaggaga tacgattgtt gtttggagat tagatagatt gggacgtaat atggaggatt
    13081 taatcacatt agttaatgag cttaacgaac gaggtgtaag tttccatagt ttagaagaaa
    13141 atataacaat ggataaatca agttcaactg gacaattatt atttcattta ttcgcagcat
    13201 ttgcagaatt tgaacgtaat ttaattttag agcgttcttc agctggccga attgcagcac
    13261 gtgctagagg ccgatatgga ggcagaccag aaaaattaaa tcaaaaagat ttaaacttac
    13321 ttaagaccct ttatgataat ggcacgccaa ttaagacaat tgcagaacag tggcatgttt
    13381 cacgtacaac aatttatcgt tacctcaata aattggagga caaggaagat gaaaaacaag
    13441 gagaagtatc taactaattt ttctgaagcc aaacgtaaaa aagctactca aaagtacaat
    13501 attataaaac cttttatcct aggcgaacaa tctttatcaa gtatttctaa aagtaaaggg
    13561 attgcgttaa gcacccttta taggtggaat aagtcatata aagaacaagg acttaaagga
    13621 ctaatctatg cgacaagagc tgataaagga acacgtaaaa tagaaccaaa gataattgat
    13681 gaaattgaac gccttgcgct tatgaataaa agaaatagta tagccacaat tcataggaaa
    13741 atcactaatt actgtaaaga aaataatttt gatataccaa gttataaaca aatttatagt
    13801 gttattaaag cgatgcctaa gtctgttatt gatttctctc atcagggtga aaaatactat
    13861 caaaataagt acgatttaat acaaattaga gaatcctcga gacccaatga aatatggcaa
    13921 gcagaccata ctttgctaga tatctttata ttagaccaaa aaggtaatat caatagacca
    13981 tggctaacta ttattatgga tgactatagt cgtgcaattg caggctattt cttaagtttt
    14041 gatgcccccc aatgctcaaa acacagcatt aacactacac caagcaatat ggaataaaaa
    14101 tgataccaat tggccagtgt gtggtatacc cgaaaaattc tacacagatc atggaagtga
    14161 ctttacttca catcatatgg aacaagtcgc tattgatttg aaaattaact tgatgttttc
    14221 gaaagttggt gttcctcgtg gtcgtggaaa aatagaacga ttctttcaga cagttaatca
    14281 aactttctta gaacaactgc ctggatatat aaacaataat gatactccta gtaatctaat
    14341 aaattttcac aattttgaag aaaaattacg ttacttttta attgaagatt ataatcaaaa
    14401 agaacatagt actattcata ccacgcctat cagtcattgg aatagtaatc actttttccc
    14461 taatatgcca agtagcttag aacaacttga tttattattg ttggaaatac ctaaatctag
    14521 aaaagttcat tcagatggca ttcattttca aggttttcga tacagtaata ctaatctaga
    14581 agcttatgta ggtgaatatg tactgattcg ttataaccca aatgatatgg ctgaaatacg
    14641 tgtgttttat agagatgaat ttctttgtac tgctatatgt ccagaaatag ctgattactc
    14701 catagatata aaagacatac agcacgctcg tagtcagaga agaaaacact taaaacaaaa
    14761 tattgctagt ccaagtacca cggaattaat taaggaagaa aaaaattgtg gttattcacc
    14821 tcaagaaacg actaaaaacg tcaaaaaatt aaagagatat cgtaatgact aaaaatcaaa
    14881 atttcattga aacgaaagag tataaacgct ttgctgaatt ttgtgatgct tgtattaaat
    14941 atcagtatat tggtatatgt tatggtcaac ctggtgtcgg aaaaacttta tcgtctaggt
    15001 attacacaaa ttgggatact attgaaaaac aagttaacca tagaggttgg gaagatttag
    15061 ctagtaaaac gaccgatgac atactatcgg tggataaaat attttataat gcaccagcag
    15121 aaaaacaaac taaattaagg aatgatttat atagtattac tgcaatcatt gatttgggtc
    15181 aaaaattaca tgttgtaaat aagtatggac atgaacatag taaacattat agtgatatgt
    15241 ttaaatatat tgatttaatt atagtagatg agattgatcg ccttaaagtg caacatttag
    15301 agcaattaag agctatttat gatgaacata atttagcaat gatatttatt ggtatgccgg
    15361 gtatagagaa aaaactatct cgttatcctc aactatattc gcgtataggt tttgcgcatg
    15421 aatttgataa tctaagtaaa gatgagacgc atcatatatt agaatataag tggcaagact
    15481 taggatttga tttaaaactc gaagacttta ctgattatga ggcaataacg acgattatta
    15541 aaattacaaa agggaatttt aggctgattc atcgtttatt tgcgcagata gacagaatta
    15601 tggatataaa tggtttagat aaaataagta cagaagttgt agaaacagct agagatagtt
    15661 tagttatagg tattcgataa tagaaaaagc aacgcatttt aatatagtgc gttgcttttc
    15721 tcatttatta ggtaaagtca ttctcatata tcgagtaaag tgacaacaat tatatatgta
    15781 tgattagggt gtacttatat cattcatata aatgtttatt tataccctca ataaaaatat
    15841 tatatgcttt taagcaccta tcacattcct tataaaaatg tttattcaat cctttaatat
    15901 cgactagcgt agtcttataa tttttttgta acaattttaa atcctcttcg taaaagctta
    15961 atttaaaatg accggcttga gctaatggct tttttccttg tttaattaaa atcaatatgt
    16021 tttttaaatg ttttaaaaag tttttataat cataaacttt tattttcatg aatgatttat
    16081 gtggattatt ttcataattt agcaggtagt tttctatatc ttcaatataa ctatcatcaa
    16141 atggtgtgtg ctggaaataa aaagttttta catacatgaa tattttataa agttcttctt
    16201 tcaaaaaatc atatgtatct aaatctcttt gtatagcatc caattttttt aatttttttt
    16261 acatttttac cacaatcctg tactcttatc catccactat tttctttaat ttcactaggt
    16321 acactttgca ttaaagtctg agatacttta ctttttaatt ccgaaatatc attaatattt
    16381 ggactaatta gtctattttc tttaactttt gtcttaaact catctaattt tttagacttt
    16441 tccgcggatt cggtagatgc tttattcatc tcaaaaacat atataggttt acctaaagat
    16501 ttagcaaaat tgtactccat ttctgtatag ctaatatttt cttcactatc aattgttcca
    16561 taactagaac ctaacaataa tatcactgca tctgattcat tgatccattg tgttattatt
    16621 tcccattggc ttttactact tgagttaaaa agttccatac ctgctggaat attattactg
    16681 tttaaaactg cttctactac tgcttgacgc tcttctatta aatctaaata agttgatgaa
    16741 ataaaaattt gatatttaat tttagtatta ctcatatatg ctcctttaat aaaaaatcaa
    16801 tttacataaa tatatcatat gataatatcc aaaaagacta cttaaaatat tatctttttg
    16861 cattcctcta ctaaccagtg ttataatcta gataacgaaa atgattaaca attaatgcac
    16921 caatccccac actactgcaa tagtgtgggg attttttcga tgctggctta taaagtcgcc
    16981 tattaattat ttgttgcgtt tactaagcca ataagtataa tacgcaacag cacagccact
    17041 gatgactggt gctatgatgt gaacgaaaat gattagcaaa gtaatgcacc tcctctctgc
    17101 gtctgaattg acgcctgaga gataggcgac ctgtatatta tatcatctcc gaatatacga
    17161 tgatagataa cttccgataa gtcgtcttat gttatataac tttgtttttt atagtatcaa
    17221 gacaagaaga aactcgtttc actcgtttca aaaaccctcc tgatttttag agaaaaactc
    17281 tcttatttca tcgtctttaa taaaataata tgccatcttt ccatctttat aaaaatcaag
    17341 tacctcattt ttatataaaa gccttaaatg atgtgaagtt gaagcaacac tcattttcaa
    17401 tatcaaagaa atatcacaaa cacacaactc atcttcttta atcaaagata atatgatttt
    17461 caatttcttc tcatcacaaa ttttttctaa aatgttaagt aatttcttag atttatcatc
    17521 ttctaaaaaa cttaaagcat tgttaacttt atcctcatgt acacagatca catcacaagt
    17581 attttcataa ctcatataaa atcacaccct aaattaaaat ataaatccta aaattgtttg
    17641 aatagtgtca ttttcaataa taataaataa acctaaagct atataaatga tagccataat
    17701 ccaacgacta aatttctcaa caatttctcc aattcctggg atattagcta atttttgtgc
    17761 agtaaacacc aagaagaaaa ttaaaattaa aaagacaaac agagtaagta ataaattagt
    17821 aacacttaat gtcacaaaat acggaacaaa taaaccaata ttatcggcgc cacaacttgc
    17881 tatcgtaaca attgcaaccg taccaactaa tttagacaat cctttttcat tcaattcttt
    17941 tttagctctc ttttctcctt cacaatcatc ataaatagcc actttaattc caagataaat
    18001 tggtattaaa cccaataaac ctaatatcca cttttctgga acataattta atacaaaagc
    18061 taaaaacaaa ctaactaata ttaaaataat agaccctaaa tattgaccaa cataaatatt
    18121 tctatattct tttctagtct ttgctctagc aaaaaatatt aataaaatta ctaataaatc
    18181 aactgctgta gcaatataaa gaacagcagc agcaacaacc gtttgaatca taatacacct
    18241 cattcaaaaa tatttttgaa tgtattataa cttatatttt taaataatca taggtgcttt
    18301 attccaattg ctttattgac gttgagcctc ggaaccctta acaatcccaa aacttgtcga
    18361 atggtcggct taatagctca cgctatgccg acattcgtct gcaagtttag ttaagggttc
    18421 ttctcaacgc acaataaatt ttctcggcat aaatgcgtgt ctatgcgtag acatggagac
    18481 acttcagaat tatggagtga ttacatgagt ttaactattt ttctttattc agttttagga
    18541 agtttattag caaattatat ctacgaaaaa tcttcaaaat aaataacttt ttcggttcta
    18601 ctttgtacac tttatctacc tggtagacct aattgttatt gctttacagg tctaaaattc
    18661 gtcgttataa tctagttaaa tcccgtaagg gcgcacttat acgtcggata aatcgacatg
    18721 tgcaaaaacg taatcgacct tcgtcgattt ttttatttca aaattaaaga aacggcttga
    18781 gatattccga gcagttataa aaattaattt gcgttgaata ttgctactac attcttgaaa
    18841 aagtgatgta gatttatagc ccataacttt tttgaattac atcgacgata cggcgtcgaa
    18901 agaaaaagct acctcacttt atctgggggg cttttatttt ttatgccctt attttgaatt
    18961 ttaagagggc attttaaaga tttaggggtg attcatatag ttttatatct aaaacttata
    19021 tacgctttta aaacgcaaat atgagccaaa taaatatatg ctattttcaa aaacaaaaat
    19081 ttgagcaaaa acaataacta ttttttagac actgcccatt tacatgcaaa ttaaaaatta
    19141 gcataaaatt ctttaaaact tccccacgtt cttctaaatt cctgcagggc ttttcttatc
    19201 aaaaacttag aaattttaat ttaactctaa aatctccgta agagcataag ggaaatttgt
    19261 ccccatcaat gaatggggga tctggcaaag ccagatattt caaggcttcg aaaatgtttt
    19321 tgtgtggggt cataaaaagc tcaagtgtca cacttttgtg acactacata cagcatttgt
    19381 cacaaaaata agacagcact ttttttacaa aaaagtaata aaaaaagaca tcagttatca
    19441 ctaatgcctt aaataataat tttgcttttc aaaattgccg taatcgaatg tgccttttct
    19501 tcttcatttg ctattttatc ttcatcactt gtattaatta aattgccatc ttcagcatcg
    19561 tctaagttta aaattttatg tttttattta agcaatccac cataacttaa catacgtttt
    19621 cgatacaaat ctttttctag atcactgaca atttcttgat tttttcatcg ctatcagtta
    19681 aaaagtcaga tgatttaacg aaatattttg atgtatcttt gattgttata aaatcatttg
    19741 aatgattgat taaagatatt atattgtttc atgtttttac ggcgcatata aagtgcatgt
    19801 gtttcttcaa attcagttaa aattgtttgc attaaataac cttgcattga cttgaatgat
    19861 tactaatttc attttcggac tctatatcat tcaagtcatt catatcattt atttcagtat
    19921 tgttagattc agtatagcta agttcagtat cattagattc tgttttatcg acttcttgaa
    19981 gtcggttttt ccgacttcct tgccattgct gctctcaaca gtgttttctt gcttttgaat
    20041 tttataaata tcatcttctg ttacttctgg tttaactaaa taaagtttat ttgtcttatt
    20101 taaaccttgt ctttcttgta gtagtaattc ggcttcaatt aagttctttc tttattttaa
    20161 ttactttatc ttttttacaa tttaatatat tttgtgggtt ttcatttttg taataaaaat
    20221 aaatattacc tgttttagaa tcaacccaac catttttaat tgataaatct aaacgatctc
    20281 taagaatacc ccatgtcatt tttgcatcat tggataactt gatatattta ggatttgtaa
    20341 aaaatacttt cggtatttga taaaactttt ctctgtattc ctcatttatg ttgtaaagtt
    20401 taattgacat aataaaaacc tctttccgaa ttttagtttg gtaagaggta ataaaacgct
    20461 tacatttttt gtgtttattt aataatctag gtgcttgcac taagatatta ttcattatat
    20521 aatctaagta tcgaaaatta tataaataaa cagtttctaa acgttttatt accaaacccc
    20581 gactattacc agtagttggg gtttttgtta tattaaggtt attatagcac tttgaataaa
    20641 cttaaaaaag ggaaaatata ggtttataaa cctttgataa acaccataaa ccctttacaa
    20701 acccttgata aaaaggttgg c
//
