LOCUS       NZ_CP089163            21807 bp    DNA     circular CON 13-FEB-2024
DEFINITION  Staphylococcus aureus strain UNC_SaCF11 plasmid unnamed1, complete
            sequence.
ACCESSION   NZ_CP089163
VERSION     NZ_CP089163.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN23701156
            Assembly: GCF_021172925.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 21807)
  AUTHORS   Wang,J., Franklin,T. and Wolfgang,M.
  TITLE     NIH Task A24 Option 3 - Murine Chronic Infection Model
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 21807)
  AUTHORS   Wang,J., Franklin,T. and Wolfgang,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) Genetics, University of North Carolina at
            Chapel Hill, 120 Mason Farm Road 5000 D, Genetic Medicine Building
            CB#7264, Chapel Hill, NC 27599, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 27-JUL-2021
            Assembly Method                   :: Flye v. 2.8.3
            Assembly Name                     :: Sa11_genome_20210727
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 54x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/13/2024 04:35:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,923
            CDSs (total)                      :: 2,842
            Genes (coding)                    :: 2,752
            CDSs (with protein)               :: 2,752
            Genes (RNA)                       :: 81
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 90
            CDSs (without protein)            :: 90
            Pseudo Genes (ambiguous residues) :: 0 of 90
            Pseudo Genes (frameshifted)       :: 51 of 90
            Pseudo Genes (incomplete)         :: 41 of 90
            Pseudo Genes (internal stop)      :: 21 of 90
            Pseudo Genes (multiple problems)  :: 20 of 90
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP089163.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..21807
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="UNC_SaCF11"
                     /isolation_source="sputum"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed1"
                     /geo_loc_name="USA: Boston, Massachusetts"
                     /collection_date="2018-07-11"
     gene            269..484
                     /locus_tag="LTK16_RS14350"
                     /old_locus_tag="LTK16_14350"
     CDS             269..484
                     /locus_tag="LTK16_RS14350"
                     /old_locus_tag="LTK16_14350"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_232043911.1"
                     /translation="MNAIQNSISLRKILVVSLSILTILSMVLDFNFKEAQAQNKNNIAD
                     KNVETLNEKEIEKEQKYIYGKIIILE"
                     /name="hypothetical protein"
     gene            complement(1638..>1920)
                     /locus_tag="LTK16_RS14355"
                     /old_locus_tag="LTK16_14355"
                     /pseudo=""
     CDS             complement(1638..>1920)
                     /locus_tag="LTK16_RS14355"
                     /old_locus_tag="LTK16_14355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(1931..2607)
                     /locus_tag="LTK16_RS14360"
                     /old_locus_tag="LTK16_14360"
                     /pseudo=""
     CDS             complement(1931..2607)
                     /locus_tag="LTK16_RS14360"
                     /old_locus_tag="LTK16_14360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            3018..3761
                     /locus_tag="LTK16_RS14365"
                     /old_locus_tag="LTK16_14365"
     CDS             3018..3761
                     /locus_tag="LTK16_RS14365"
                     /old_locus_tag="LTK16_14365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843758.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     gene            complement(3980..4165)
                     /locus_tag="LTK16_RS14370"
                     /old_locus_tag="LTK16_14370"
     CDS             complement(3980..4165)
                     /locus_tag="LTK16_RS14370"
                     /old_locus_tag="LTK16_14370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            4314..4385
                     /locus_tag="LTK16_RS14375"
                     /old_locus_tag="LTK16_14375"
     CDS             4314..4385
                     /locus_tag="LTK16_RS14375"
                     /old_locus_tag="LTK16_14375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(4624..4965)
                     /locus_tag="LTK16_RS14380"
                     /old_locus_tag="LTK16_14380"
     CDS             complement(4624..4965)
                     /locus_tag="LTK16_RS14380"
                     /old_locus_tag="LTK16_14380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(5052..5912)
                     /locus_tag="LTK16_RS14385"
                     /old_locus_tag="LTK16_14385"
     CDS             complement(5052..5912)
                     /locus_tag="LTK16_RS14385"
                     /old_locus_tag="LTK16_14385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            complement(6296..6832)
                     /locus_tag="LTK16_RS14390"
                     /old_locus_tag="LTK16_14390"
     CDS             complement(6296..6832)
                     /locus_tag="LTK16_RS14390"
                     /old_locus_tag="LTK16_14390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="WP_221554688.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDSYTL"
                     /name="recombinase"
     gene            complement(6926..7555)
                     /gene="mobV"
                     /locus_tag="LTK16_RS14395"
                     /old_locus_tag="LTK16_14395"
                     /pseudo=""
     CDS             complement(6926..7555)
                     /gene="mobV"
                     /locus_tag="LTK16_RS14395"
                     /old_locus_tag="LTK16_14395"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            complement(7793..8419)
                     /locus_tag="LTK16_RS14400"
                     /old_locus_tag="LTK16_14400"
     CDS             complement(7793..8419)
                     /locus_tag="LTK16_RS14400"
                     /old_locus_tag="LTK16_14400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(8431..8742)
                     /locus_tag="LTK16_RS14405"
                     /old_locus_tag="LTK16_14405"
     CDS             complement(8431..8742)
                     /locus_tag="LTK16_RS14405"
                     /old_locus_tag="LTK16_14405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            complement(8746..10680)
                     /locus_tag="LTK16_RS14410"
                     /old_locus_tag="LTK16_14410"
     CDS             complement(8746..10680)
                     /locus_tag="LTK16_RS14410"
                     /old_locus_tag="LTK16_14410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(10755..11048)
                     /locus_tag="LTK16_RS14415"
                     /old_locus_tag="LTK16_14415"
     CDS             complement(10755..11048)
                     /locus_tag="LTK16_RS14415"
                     /old_locus_tag="LTK16_14415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            complement(11462..12070)
                     /locus_tag="LTK16_RS14420"
                     /old_locus_tag="LTK16_14420"
     CDS             complement(11462..12070)
                     /locus_tag="LTK16_RS14420"
                     /old_locus_tag="LTK16_14420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001566953.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            complement(12439..13284)
                     /gene="blaZ"
                     /locus_tag="LTK16_RS14425"
                     /old_locus_tag="LTK16_14425"
     ARG             complement(12443..13284)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            13391..15148
                     /gene="blaR1"
                     /locus_tag="LTK16_RS14430"
                     /old_locus_tag="LTK16_14430"
     ARG             13392..15145
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.56"
                     /coverage="100.0"
     gene            15138..15518
                     /gene="blaI"
                     /locus_tag="LTK16_RS14435"
                     /old_locus_tag="LTK16_14435"
     ARG             15139..15515
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            15782..16375
                     /locus_tag="LTK16_RS14440"
                     /old_locus_tag="LTK16_14440"
     CDS             15782..16375
                     /locus_tag="LTK16_RS14440"
                     /old_locus_tag="LTK16_14440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            16347..17790
                     /locus_tag="LTK16_RS14445"
                     /old_locus_tag="LTK16_14445"
                     /pseudo=""
     CDS             16347..17790
                     /locus_tag="LTK16_RS14445"
                     /old_locus_tag="LTK16_14445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            17783..18598
                     /locus_tag="LTK16_RS14450"
                     /old_locus_tag="LTK16_14450"
     CDS             17783..18598
                     /locus_tag="LTK16_RS14450"
                     /old_locus_tag="LTK16_14450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            18951..19532
                     /locus_tag="LTK16_RS14455"
                     /old_locus_tag="LTK16_14455"
     CDS             18951..19532
                     /locus_tag="LTK16_RS14455"
                     /old_locus_tag="LTK16_14455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_232043910.1"
                     /translation="MNAIQNSISLRKILVVSLSILTILSMVLDFNFKEAQAQNKNNIAD
                     KNVETLNEKEIEKELKYIYGKIIILDKDGTAKDVNLENAKSRYGYVPEGFQKLKNDIEN
                     KKKTSSISPRAVGGNYKNSGDCFYSEVLNSYGELLTGNIITAVFEDVKAKNLKGVAKKL
                     SKIGIKGNLAGIAATMVSKDVQCNLKYGLL"
                     /name="hypothetical protein"
     gene            complement(19858..20046)
                     /locus_tag="LTK16_RS14460"
                     /old_locus_tag="LTK16_14460"
     CDS             complement(19858..20046)
                     /locus_tag="LTK16_RS14460"
                     /old_locus_tag="LTK16_14460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001039248.1"
                     /translation="MNKNTVLDEGYVIATILNVFFLLGLIFISHLENLYILIPYVILMG
                     INAIYLVVKVMNFKKNN"
                     /name="hypothetical protein"
     gene            complement(20629..21624)
                     /locus_tag="LTK16_RS14465"
                     /old_locus_tag="LTK16_14465"
     CDS             complement(20629..21624)
                     /locus_tag="LTK16_RS14465"
                     /old_locus_tag="LTK16_14465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="WP_001199892.1"
                     /translation="MQYNTTRSITENQDNKTLKDMTKSGKQRPWREKKIDNVSYADILE
                     ILKIKKAFNVKQCGNILEFKPTDEGYLKLHKTWFCKSKLCPVCNWRRAMKNSYQAQKVI
                     EKVIKEKPKARWLFLTLSTKNAIDGDTLEQSLKHLTKAFDRLSRYKKVKQNLVGFMRST
                     EVTVNKNDGSYNQHMHVLLCVENAYFRKKENYITQEEWVNLWQRALQVDYRPVANVKAI
                     KPNRKGDKDIESAIKETSKYSVKSSDFLTDDDEKNQEIVSDLEKGLYRKRMLSYGGLLK
                     QKHKILNLDDVEDGNLINASDEDKTTDEEEKAHSITAIWNFEKQNYYLRH"
                     /name="protein rep"
     ARG             complement(12440..13284)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             5755..16048
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(1434..1581)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          complement(20395..20559)
                     /name="MOB_unknown"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="2.42e-81"
     Typing          3019..3761
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(5053..5912)
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(20630..21624)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.799"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(7281..7555)
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 cactcgtttc aaaaaacaac ctattccttc ttctttttat gaccctctaa acctaaataa
       61 attaatgtga aaaccaatga ataaataaaa ctttctaaaa agtcaaaagg attatcaaat
      121 aaaatcgaat taacaaaatt aaaaattaaa aatacagata ataaaataat caaaaagtaa
      181 aaaaacttat tcatattaaa ctcctttgtt tttatatgtt aatattatat tgaattcatt
      241 taaataacaa aacaaggggg catttacaat gaatgcaatt caaaacagta tatcactaag
      301 aaagatttta gtagtatctt taagtatttt aaccatactt tcaatggtct tggattttaa
      361 tttcaaagaa gctcaagccc aaaacaaaaa taacattgca gataaaaacg ttgaaacttt
      421 aaacgaaaaa gaaattgaaa aagaacaaaa atacatatat ggcaaaatta ttattttaga
      481 ataatcatag gtgctttatt ccaattgctt tattgacgtt gagcctcgga acccttaaca
      541 atcccaaaac ttgtcgaatg gtcggcttaa tagctcacgc tatgccgaca ttcgtctgca
      601 agtttagtta agggttcttc tcaacgcaca ataaattttc tcggcataaa tgcgtgtcta
      661 tgcgtagaca tggagacact tcagaattat ggagtgatta catgagttta actatttttc
      721 tttattcagt tttaggaagt ttattagcaa attatatcta cgaaaaatct tcaaaataaa
      781 taactttttc ggttctactt tgtacacttt atctacctgg tagacctaat tgttattgct
      841 ttacaggtct aaaattcgtc gttataatct agttaaatcc cgtaagggcg cacttatacg
      901 tcggataaat cgacatgtgc aaaaacgtaa tcgaccttcg tcgatttttt tatttcaaaa
      961 ttaaagaaac ggcttgagat attccgagca gttataaaaa ttaatttgcg ttgaatattg
     1021 ctactacatt cttgaaaaag tgatgtagat ttatagccca taactttttt gaattacatc
     1081 gacgatacgg cgtcgaaaga aaaagctacc tcactttatc tggggggctt ttatttttta
     1141 tgcccttatt ttgaatttta agagggcatt ttaaagattt aggggtgatt catatagttt
     1201 tatatctaaa acttatatac gcttttaaaa cgcaaatatg agccaaataa atatatgcta
     1261 ttttcaaaaa caaaaatttg agcaaaaaca ataactattt tttagacact gcccatttac
     1321 atgcaaatta aaaattagca taaaattctt taaaacttcc ccacgttctt ctaaattcct
     1381 gcagggcttt tcttatcaaa aacttagaaa ttttaattta actctaaaat ctccgtaaga
     1441 gcataaggga aatttgtccc catcaatgaa tgggggatct ggcaaagcca gatatttcaa
     1501 ggcttcgaaa atgtttttgt gtggggtcat aaaaagctca agtgtcacac ttttgtgaca
     1561 ctacatacag catttgtcac aaaaataaga cagcactttt tttacaaaaa agtaataaaa
     1621 aaagacatca gttatcacta atgccttaaa taataatttt gcttttcaaa attgccgtaa
     1681 tcgaatgtgc cttttcttct tcatttgcta ttttatcttc atcacttgta ttaattaaat
     1741 tgccatcttc agcatcgtct aagtttaaaa ttttatgttt ttatttaagc aatccaccat
     1801 aacttaacat acgttttcga tacaaatctt tttctagatc actgacaatt tcttgatttt
     1861 ttcatcgcta tcagttaaaa agtcagatga tttaacgaaa tattttgatg tatctttgat
     1921 tgttataaaa tcatttgaat gattgattaa agatattata ttgtttcatg tttttacggc
     1981 gcatataaag tgcatgtgtt tcttcaaatt cagttaaaat tgtttgcatt aaataacctt
     2041 gcattgactt gaatgattac taatttcatt ttcggactct atatcattca agtcattcat
     2101 atcatttatt tcagtattgt tagattcagt atagctaagt tcagtatcat tagattctgt
     2161 tttatcgact tcttgaagtc ggtttttccg acttccttgc cattgctgct ctcaacagtg
     2221 ttttcttgct tttgaatttt ataaatatca tcttctgtta cttctggttt aactaaataa
     2281 agtttatttg tcttatttaa accttgtctt tcttgtagta gtaattcggc ttcaattaag
     2341 ttctttcttt attttaatta ctttatcttt tttacaattt aatatatttt gtgggttttc
     2401 atttttgtaa taaaaataaa tattacctgt tttagaatca acccaaccat ttttaattga
     2461 taaatctaaa cgatctctaa gaatacccca tgtcattttt gcatcattgg ataacttgat
     2521 atatttagga tttgtaaaaa atactttcgg tatttgataa aacttttctc tgtattcctc
     2581 atttatgttg taaagtttaa ttgacataat aaaaacctct ttccgaattt tagtttggta
     2641 agaggtaata aaacgcttac attttttgtg tttatttaat aatctaggtg cttgcactaa
     2701 gatattattc attatataat ctaagtatcg aaaattatat aaataaacag tttctaaacg
     2761 ttttattacc aaaccccgac tattaccagt agttggggtt tttgttatat taaggttatt
     2821 atagcacttt gaataaactt aaaaaaggga aaatataggt ttataaacct ttgataaaca
     2881 ccataaaccc tttacaaacc cttgataaaa aggttggcga atttatattt ttatttgtcg
     2941 attactttat tattaatcgt tataagctta taatatttta ctaagggttt ataaacattt
     3001 tataaagggt tgatgatatg aaaagtgtaa aaaggttgag tgaagaatta ggggttagta
     3061 agcaaacgat ttttaataat attaagagat tgaatataga gacaataaaa caggaaaaca
     3121 cttcgtttat taaagaagat accgatatag aaaaaatcat tcaaagagta aatgaaaata
     3181 aaaagaaata tggttttgaa agtgctactg aagacaaaca aaaaaaagag tcggataata
     3241 ttaattttga atctaaaagc gatgctcaaa tagtagaaat acttaaaaat cagattaata
     3301 ctttaaataa tcaaattgaa aaacaagaaa gtcgtcatga aacaacaatt gaattttaca
     3361 gaaaagagtt gcaagaaaga tcaaaattgc ttgagaatca gcaagttctg gcattagaga
     3421 gtaataaaaa gattcaaaaa ttagaaaatc aattagaaaa agaaaaacac cttaattatc
     3481 cctttgatac atctactaac gctagacaaa acgttgatgc acaagaaaaa acatatacta
     3541 ctagtcctgt aaatattaac cgagatcagg aagaaactaa agaaacagag attcaatata
     3601 aggatatatc tggaagtcaa agcgacgaaa gtacacaagg tgaagaagca caaagagaag
     3661 acgtttcagc taatccaaat gacaatgata gtgatataga agaaaagagt gaagaaacgg
     3721 aacctaaaaa ggggttttgg agtcgtctat ttggtaacta attttaatta aaaaggtacg
     3781 acaagttcat aaattagccg tgctttttta tgtgaattga acttctgata atcatcgatt
     3841 atgttaacca aacaaaaagc cataaatgcc tatatgacgg catttatggc tttttacttt
     3901 cattatcttt tatgcatctt ttatacatcg ttgatttgac gcgttttcat tcttttgcat
     3961 tggcaagtat tttgtatctt tattcagtta ctatttcttt tctccaacct aacaaaccat
     4021 ctttaactct aataatatgt ttgccacgcc agacacttct tacttcgaaa taataccatt
     4081 ccccgttttt gttgaggaaa taaatatctt gataaccttc tttaatgaca tattttgtag
     4141 cttcttgtct ttgatcgcca aacattatca atcccaccct tatatttatt tatctttaat
     4201 atataacaac atttattaat attcatgtta tttcatggaa ggagagattt gttataatgt
     4261 gaaggtcgtc tatctctcag atgtcaattc ggcgtagaga ggaggtgcga tttatgaatg
     4321 aaattcttgt tcacatcatg acaacggcaa tcagtggttg tctcgttacg ttatttggtt
     4381 attagctcca taaacgtgat aaaaaataat atagacgatt aaagccaatt caccaaaaaa
     4441 ccccgaacta cggcgaatag ttcggggttt tgtgcgttta caaacgaaat tcttgttact
     4501 tttagtatat atttcatatt gccttttgta aactcttcta ttcttatcaa tacatttcaa
     4561 ggtgtcgtaa aaatactttc ctttttcata ttgcctgatg tgcattaaat tttgatttta
     4621 aaatcaaccc atgaacgaat gaatggccca aactaaaaat ccggcaacag gaaagaaaag
     4681 ccaccaaaaa tcataaagaa aatcaactat ggaaggtacc ctgttactct ctctataatt
     4741 tccctctaaa ataacttttt taaaacgtgc atctccttta attaaatgct ctaaagagat
     4801 tccgaataaa tcgctcatag caatcaaaat atctaaggaa ggatagtttt tggcactttc
     4861 ccatttagaa acactttgtc tggaaacctt taatatattg gctaattcct cttgagacca
     4921 tccttttaat tctctctgtt cttttatagc ttcagctaat ttcataaaat cactccttaa
     4981 ctcaaactat aattaaaata attgaaaagt cacgatactt ttagttaacc aactcgcaac
     5041 gaaaagttgc gttattccca attcagttca agttgtttta aaaaatcctc tcgttctttc
     5101 tctaattgtg ggtcgtaatc tttttgaggt tgcttttcat atgaccgttc ttctaaccat
     5161 ttaggcgtct tttcacgcct cacatattgt cttgatttat ctatcttgga catttgaggt
     5221 tgtcgtttgt tatgaatgcg tttctcagcg tcaaatgtga actctatcca ttcaatttta
     5281 cgcccttttt tcgctttgat tttattgata gtaagattat taaatataga acctaattca
     5341 ataataatag gtttaaaaac atttttgtta atatcagtca tacgataaga tttaggtata
     5401 tctaaacgat ttttaaaatc atcgatgtga atttttaaat agcctgtatg tttgtattgt
     5461 ttaagtaatc taaacatatt tttagaatat gtagatttaa gcctagtcat ttcttttaat
     5521 tcaaattttg taaaattatt agtaattgaa ttcaatatgt gttttaaatt tgaagaagtt
     5581 gatatttcta gatattgttc tcgcttatgg attctataat gattgaataa aacgaatctt
     5641 tctattacat catcatcttc atatctaatg gttaaattca acatcttttt atacacatta
     5701 tctaaatcat tagcaaatct attaatatta cgtgtttctg gactataatt acttaatttt
     5761 tttaattcat caaaagacaa acgtaatgta ttagtatctt gctcttttaa tttattacac
     5821 atcgcaaaaa ataaattaat ttcagtagct gtaaatcgcc ttaatggaac taaattcatt
     5881 tcatttttat atacaactgt ctctcctgtc atgatacagc cccctttatt acgaacctaa
     5941 aggagtatcg tttgaatata cactcccatt tgaaaacttt tattcacaat aaactacttt
     6001 attatcaatg tcaaaccata aaaggagtac aactttttaa aacactcctt ttatgtggca
     6061 aaaacactcc ttttatgtgg caaaaacact ccttttatgt ggcaaaaaca ctccttttat
     6121 gtggcaaaaa cactccttta ggcattgaaa tcccttgttg ctctagggct gaacaagccc
     6181 ctaaaaaggt ttttaaaaag atttataaaa atatattaaa aagttcgagg ggggctacct
     6241 atttttcatc ctaaaaaata attaacctca aacaaatgca tttaaatatc tatttttata
     6301 atgtataact atcttcttta aaaatgattt ctcgttcttg tgcttgatat ttcttcttaa
     6361 agaactgttc atcattgtta tctatcgtca ttacttcacg tattttagaa ttgtctaaat
     6421 gattatcaat atgatttatt agtgtatgat aacgctcttc tttcatcata cttttaatga
     6481 ttttaaaaac ttgattgaat aacttaagcg tataatttag ttctttatct ttcttttcat
     6541 tctctgacaa caaataatta taacgttgtg ctaaatcatt aaattcttca accagctttt
     6601 cattttccat atggacacta gtcaattcat taactaaact ttcattttgt ttctctgctt
     6661 tttttaatga cttcccactt ttaatacatt cataatcatc taatatcatc tgtgctgctt
     6721 taatttgttt agtgtatttt tcaaaatcag ttttagtaat tacaatattg cctgtttctt
     6781 gcttctcttt atgaaaccat ccacctacat ttttagtttt aatttcatac atgacactca
     6841 gaagcttttt aagcgtatct aatgattttt ggtagttttg tatcaattta tcattttctt
     6901 gctttaaata atcctctatt tgcttctagc gcatatgcat ttgtttatga tattctgttt
     6961 tttgtttata acggctaact tgatcatgtt tttcttttgt aagttgtcta gaaattcctc
     7021 gttttaaatc atagccttgc ttattaatat acgtattgaa tctatcttgg aattcggtta
     7081 atgctttttt attacctaca acttctttcg cacttaaacg tccatcttta gtaataggaa
     7141 ctacgccata atgcatatgt ggtgttatct catccatatg tactgtcgca tataaaagat
     7201 tttctttacc gtattcttct tccaagaacg ctttagcatg cttaaaaaac tattttgtct
     7261 cttcttcaga taattgatta aaaaacacat tatctgatgt aattaatcca tcaatatgtt
     7321 taatggcatc tgttctaatt ttgcgtttcc ctttataatt tttttcgatt ttctcatcaa
     7381 tttttttatt aaaatcaaac ttagtatcat tgactaaatc atagtttaaa tatgacttac
     7441 ttaaatcaat atctatattt tcataatttt tattttctct ttgaatatgt ctttgaatac
     7501 ctcttgtatt tgtttttgat ttcactttaa caactcgaat aattgaataa gacataataa
     7561 atcaacttcc actgcatatg attataacac ctaaacacag aaaagtttta acatactaga
     7621 cttattaaaa accaaataag tcattaaaaa cgtgtgctct gcgaggcttg ttttttgtca
     7681 tcataaaaaa ggactggaaa atccagtcct taaattaaaa aactcaaaag taatgactaa
     7741 tcatatttca tattgttttt tctctatgta tggctatacc tatcaatatt tcttaacttc
     7801 taagctcaga aatattgact atgacatcaa atcgtttcgc aagctctaaa tcatgcgtta
     7861 cgacaatcat agttttattt tcatcaagta gcttcaataa taaatcaata actatttttc
     7921 catttttcgt atctagtgac ccagtaggtt catcagctaa aatgattttc ggatctttta
     7981 atattaatct tgccaatgct actctttgtt gttcaccacc gcttagagaa ctaacaattc
     8041 tcttgatatc taaatctagg ccgacctttt ttaatacttc tttctttaag ttcatattat
     8101 cttttttatt ctttttgaac tttagggcta aatctaaatt ttgactgatt gtttgatttt
     8161 caagtaaagc aaaattttga aacaaatacc ctaacgtata tctataaaaa tcgactttct
     8221 tttttagtaa cttatcttca atatatatgc ttccttgtga tacatcttcg aacccagcga
     8281 ttatgttaag taaagtagat tttccagcgc cactttctcc aactaaagca tatgattttc
     8341 ctttttcaaa attaaagtta catccgtcta aaatgttttt attacctttt tttacaaaaa
     8401 cattttcaag ttttatcact atcggtcacc tcattttaaa aagctaggaa tatcttttgt
     8461 aatgtattct atcgaacgca catatttccc tttatgattt actttcacat attcttttgt
     8521 aggatcataa cctaaaaaat ccaatttata actctttttt tctccatttt tagagtatac
     8581 agttatattt ctatagtcct gggtatcttt tggaactttg gcataagata ctttttcttt
     8641 taacagtggg ttaaaacgat ctaaatgctc atttctaacc aataacagac taagtatgat
     8701 gattaatagt acaattgtta caataattaa agttcttttc attgtttaaa tctccctcat
     8761 taaatcttta aagtattttt caagatattt aatataagca atttgaagta aatgttgaat
     8821 aatagcaata gacattatta tgaatagtaa tatctttgaa ccaaataaaa tatgcgtagt
     8881 gtaagctaac ataatagaaa gtaagataga aattgttaaa taacgtacat tactgctgaa
     8941 taatgaataa ccatgaattt ttcttaataa tagttgcttt ttattccagc taaaatattg
     9001 aattgtttca aatacagtag ctatcaaaag aatgaaaacg ttaataataa tagtaactat
     9061 tgttattatc atttttgttt tcgtttcatt taattcattt aacacagaat ccttgtaatt
     9121 agttataccg ctaatttctt cttctaggtg attatcttta agcaactgtt taagtgtatc
     9181 taaatcttta aatagatatc caccttgaga aacagcagct aaataaaaat ctcctgttaa
     9241 atcgtcaagt gtcaacaaca ttactattgg agaatctaga tacccaaatt tcaaattagt
     9301 tgtgcgatca aaagaaaaaa cagatacgtt ttttgacagt acttgcacat ctactttttt
     9361 gttttgttgc ttttgaaagt caatccatcc ttggtgattt ttttgaattt cagatttttg
     9421 atattgtaac cttggaggaa taaacacgtt tattttatcc gaatgattgt caatcatttt
     9481 aaaatcatga tttatatttt tatagaaatt cagaaaattg ttattgataa aaaagacatt
     9541 gccattttca ggaatgtaat tgtttttatc gggattggct atattattat tctttaaaag
     9601 caatccacca agttgttcgc ttttcttaat taaattgtat atattagttt ctaaaatttg
     9661 tttttcttct gaatttctaa tattaggaga aatctctaat gtatagtaat tatctaactt
     9721 ttgccagatt ttttcagagt catatatatt ctttaacttc gtataagcat ttaaattttg
     9781 tgccagtaaa aaagatagta ttagcaccat gatacatttg gtgaaggtac ccataaatat
     9841 tgaaaactta tatccttttt tcccttttaa gattaatgga atacttaact tcaaaagaag
     9901 actatacgaa atcagccaca gcaatgtagt aatacaagca aaaacaaaaa gcaacacgat
     9961 aaatctacga ataaacatta agaaatccaa ttctaaattg gctatatgaa tgattaatat
    10021 attagcaata aagaaaatag cggtaagtac tagccaataa atgattttta tatgaatatt
    10081 atgaaaaata atgcgtgtag ttgaaaagcc atgtagcttt tgaatagcat aaaatttcaa
    10141 attatatcct ctgtcatata agaagtacaa aagatataat acgcctaaga atatgaaagg
    10201 cactaataaa tcattatcta tgactaattc aaaaaataat atgtttctat ttatgtattc
    10261 aacttcagat gttaaaccag ctttttttaa ttcactcgta agctcttcta cattgaaatg
    10321 ttcaccaata atataatact ttccttttat ctctctgttt aataaatctg atggagttaa
    10381 aagtgatgtt ttattacgta taaagtcaga attatttcgt tttgagttga aaacaaaaaa
    10441 ttctttttta ttatcaaaat ctttaacgga tttaattatt tgtatatttt gatttttggc
    10501 gcctgattca atgacatcta acacttttga tttactgtta gatttatccc aattagagat
    10561 tgttaaaata ttggaacttt caggtataat ttcttcattt tctttgaaga aaaataaaaa
    10621 taatagccct gaaattaata ataaagtact aaaatctaaa aataatttga attttttcat
    10681 attgcctctt tcaagagaat agacagaatt aagtttactt aattctgtct attctcctta
    10741 attaatatat gtaattagtg aagactataa aatgttttgt ttccacccca agcctttgga
    10801 gcagatgcct tagattgaac accaggtcga gcaacaccac taaaagatga atatttccct
    10861 actgctgttg aaccatgatt tcttttattg tgactataat aagaccatac gtaatgtttt
    10921 ccaataccat ggctccaaac accaccagct acatgtactg ttgcagcttc agctttataa
    10981 gttacaccta ataaagtgcc gaataagatt gtactagcaa tacaactaga aacaaatttc
    11041 tttttcataa aaacacctcc atttaatatt ctttatttat tatagcaaaa ataaataaaa
    11101 tagagaatga gtaaaaataa tctaaaagtg ttttttctgc tctgttgctt gttttgttca
    11161 tctatatata atattaattc tattatcctt aaattaacta tcattaaaca acgatatgac
    11221 aatgtataat aaatacaatt tcactaccta taattcaaca ttatataaac taaagtattt
    11281 caaataatta actgtattaa tactctcatc atgattgcgt tataaacatt cgttaatgag
    11341 aaaaagagag agcatattta cgctctcttt tcttgtctta ttattaaaaa ctcataatag
    11401 attataatca tctgttttga gacgctgtga gaagctctca gttgcattga aacaaagttt
    11461 attaaatcaa atcattatcg tttttaattc tgtaaatcgt ctgccttgtt atatttactt
    11521 ctttcgcaat tttactaatt gattggcctt cttctaacat ttctacaacg cgatgataaa
    11581 taatacgttt ctgtggatct ttagcatttg gtgaataaag taaggggcgc cctttatata
    11641 cgcctttttc cttcgcaact tgaattcctt gcgcttgtcg acgtttactt tcatttctct
    11701 cttgttctga aaccattgct aatatttgaa taattaaatc tttcataaac ttatccagta
    11761 atggattgcc aaccacttca ttcatcatag gtaagctagt aatcattaat tgtacttctt
    11821 tgtcttttaa ataattaacg gtatgaatca cttcatcata attacgacct aaacaatcaa
    11881 tggattctac tacaaaccga tctcccatcc tcaaaaagtt aagtgcttct tgaagtactg
    11941 gtctattttc aatagatttc ccagactgtt tttctgtaaa tattttttca gcacaaaacg
    12001 tctttaaatt ttcaagttgt ctttctaaat tttgatcgtt cgatgatact ctcgcatagc
    12061 caacaatcat tgatttccat ctcataatta atatacaccc taatcatacg tttcagttac
    12121 tataaattca acaattatgt cactttgctt gatatatgag aattatttaa ccttataaat
    12181 gagaaaaaag caacgcactt taaataagat acgttgcttt ttcgattgat gaacacctat
    12241 aattaaacta ttcatctatt atttatgatt ttttgtatat acaatatttc tagtttgtta
    12301 aagagaatta agaaaataaa tctcgaaaat aataaaggga aaatcaggtt ttgatatcaa
    12361 aattatacat gtcaacgata atagaaaata taatacaaac tataagatgt tatcagtatt
    12421 tattatgcat ttagaatatt aaaattcctt cattacactc ttggcggttt cacttatcaa
    12481 cttatcattt ggcttatcac ttttattgtc tttattcgta aaaatgacta aaacaatagg
    12541 ttcagattgg cccttaggat aaacaaaagc aacatcattt ctagaagcat atgttattgc
    12601 ttgaccactt ttatcagcaa ccttatagtc ttttggaaca ccatctttaa ttaaagtgtc
    12661 tccgttttta ttattaaaca ttaaatcaag taagaaattt ttattttttt tgcttaattt
    12721 tccatttgcg ataagtttat ttaaagtctt gccgaaagca gcaggcgttg aagtatcttt
    12781 tttgctcttt ggcgaatagt aatttaattc tatctcatat ctaactggat ttgttacttt
    12841 atctcctagt tcttttagac gttgtttaac ttttttgatt ccaccgattt cttttataat
    12901 tttattgttt gctgtattat cactatatgt cattgaagcc tcaataagtt cttttaaagt
    12961 gatgtctttt cctacatatt tttctaaaat aggagaataa gcaactatat catctttgtt
    13021 aatatgtact tttttattta acttattata aggtacttgt tctaacaaaa tagcactatt
    13081 tatcgctttt gaagtcgaag cataggcaaa tctcttatct gaattaaatt ttacttcctt
    13141 accactttta gtatctaaag cataaacacc aatatgagca ttatattttt tttctaaatc
    13201 atttaactct ttggcatgtg aactgtttga attacatgca cttaaaacta aagccattac
    13261 aattaaaaat attaactttt tcaaaataaa ccctccgata ttacagttgt aatttttaca
    13321 aaacaataat attacaattg taatattgat gtcaattgtt tattataaat atttgaaaga
    13381 aggtgtcaaa atggctaaat tactaataat gagtgtagta agcttttgtt ttatatttct
    13441 attgttagta ttttttaggt acatattaaa acgctatttt aattatagtt taaattataa
    13501 agtttggtat ctaactgtgc ttgctggatt aattcctttt atcccaatta aattctcttt
    13561 tataaaattt aataatgtga ataatcaagc gcccacagtt gaaagtaagt cacacgactt
    13621 gaaccataac ataattacca ccaaacctgt tcaagagttc gcaacagata tccataagtt
    13681 taattgggat tcaattgata atatctgcac agttatttgg atagttttag ttattatttt
    13741 aagttttaaa tttttgaaag ccttattata tcttaaatat ttaaagaaac agtcacttta
    13801 tctaaacgaa aatgaaaaaa ataaaataga tacgatactt ttcaaccatc aatataaaaa
    13861 aaatattgtg attcgaaaag cagaggctat tcaatctcca ataacttttt ggtatgggaa
    13921 atatattatt ttgattccta gttcatattt taaaagtgta attgataaaa gactaaaata
    13981 tataatactg catgaatatg ctcatgctaa aaatagagat actttacatt taattatctt
    14041 taatatcttc tctattatta tgagttacaa tccattagta catattgtaa aaagaaagat
    14101 aattcatgac aatgaagtag aagccgatag atttgtcctt aataatatta acaaaaatga
    14161 atttaaaact tatgcggaat ctattatgga ctccgtatta aaaacctcat ttttcaacaa
    14221 aaatatatta agccattcat ttaatggtaa aaaatcatta ctcaaaaata gattaattaa
    14281 tataaaagaa gccgatctga aaaagcagtc aaaattaatt ctaattttta tttgtatttt
    14341 tacttttttt atcatgataa ttcaaagcca gtttttaatg gggcaatcct taactgatta
    14401 taattataaa aagcccttac aaagcgatta ccaaatttta gatgaaagta aaaattttgg
    14461 ttcaaatagt ggatctttcg ttatgtacag catgaagaaa gacaaatact atatttataa
    14521 tgaaaaagaa agtagaaaaa gatattctcc tgattcaact tacaaaattt atttagcact
    14581 gtttggactt gaccgtcata ttataagtga taaaaattca cgtatgtcat ggaatcataa
    14641 acattatctt ttcgagtctt ggaataagga acaagattta aatacagcaa tgcaaaattc
    14701 agttaattgg tacttcgaac gtattagtaa tcaaatacca aagaactata ctgcggctca
    14761 actcaagcaa ttaaattatg gtaatgaaaa tttgggaagt tataaaagct attggatgga
    14821 agatagtttg aaaatatcta atcttgaaca agtaatagtt tttaaaaata tgatggaaca
    14881 aaataaccat tttagtaaaa aagcaaagaa tcaattatct tcttcattat tgattaagaa
    14941 aaatgaaaag tatgaactgt atgggaaaac aggtacaggt atagtaaacg ggaagtataa
    15001 taatgggtgg tttgtaggtt acgtaattac aaatcatgat aagtattatt ttgctacaca
    15061 tttatcagat ggaaacccgt ctgggaaaaa tgctgaatta ataagtgaaa aaatattaaa
    15121 aggaatgggt gttttaaatg gccaataagc aagttgaaat atctatggct gaatgggatg
    15181 ttatgaatat aatatgggat aaaaaatcag tatcagctaa tgaaattgta gttgaaattc
    15241 aaaaatataa agaagttagt gataaaacga ttagaacatt aatcacaaga ctatataaaa
    15301 aagagattat aaaacgatac aaatcagaaa atatttattt ttactcatca aatattaaag
    15361 aagacgatat taaaatgaaa actgctaaaa cctttcttaa taaactgtat ggaggggata
    15421 tgaaaagttt agtgttgaat tttgcgaaaa atgaagaatt aaataacaaa gaaattgaag
    15481 aattgcgaga tattttaaat gatattagta aaaagtaatt agaggtatgt ttcaaacata
    15541 atacatatgt aaactatgct tgactcttat taaattagtt ttgttaatga catttaaaat
    15601 atattattaa agatgagagt gtacagaaaa taaccatttt ctgtacactc ttcttttatg
    15661 tctaaataag taagaattac ataggattat gtgttcaaaa acccaacaaa aaatctatgt
    15721 tcataaaaga ccttgtaatt aagttatggt acactgaaga tgtatatagg aggtttgtat
    15781 tttgaaaata ggttatgcaa gagtttcaac tggattacaa aatttaaatt tacaggagga
    15841 tcgattaaat acatatggtt gtgaaaagat atttaatgac catatgagtg gttcaaaaag
    15901 taaaagacct ggtttagata aagcaattga atttgcgagg tcaggagata cgattgttgt
    15961 ttggagatta gatagattgg gacgtaatat ggaggattta atcacattag ttaatgagct
    16021 taacgaacga ggtgtaagtt tccatagttt agaagaaaat ataacaatgg ataaatcaag
    16081 ttcaactgga caattattat ttcatttatt cgcagcattt gcagaatttg aacgtaattt
    16141 aattttagag cgttcttcag ctggccgaat tgcagcacgt gctagaggcc gatatggagg
    16201 cagaccagaa aaattaaatc aaaaagattt aaacttactt aagacccttt atgataatgg
    16261 cacgccaatt aagacaattg cagaacagtg gcatgtttca cgtacaacaa tttatcgtta
    16321 cctcaataaa ttggaggaca aggaagatga aaaacaagga gaagtatcta actaattttt
    16381 ctgaagccaa acgtaaaaaa gctactcaaa agtacaatat tataaaacct tttatcctag
    16441 gcgaacaatc tttatcaagt atttctaaaa gtaaagggat tgcgttaagc accctttata
    16501 ggtggaataa gtcatataaa gaacaaggac ttaaaggact aatctatgcg acaagagctg
    16561 ataaaggaac acgtaaaata gaaccaaaga taattgatga aattgaacgc cttgcgctta
    16621 tgaataaaag aaatagtata gccacaattc ataggaaaat cactaattac tgtaaagaaa
    16681 ataattttga tataccaagt tataaacaaa tttatagtgt tattaaagcg atgcctaagt
    16741 ctgttattga tttctctcat cagggtgaaa aatactatca aaataagtac gatttaatac
    16801 aaattagaga atcctcgaga cccaatgaaa tatggcaagc agaccatact ttgctagata
    16861 tctttatatt agaccaaaaa ggtaatatca atagaccatg gctaactatt attatggatg
    16921 actatagtcg tgcaattgca ggctatttct taagttttga tgccccccaa tgctcaaaac
    16981 acagcattaa cactacacca agcaatatgg aataaaaatg ataccaattg gccagtgtgt
    17041 ggtatacccg aaaaattcta cacagatcat ggaagtgact ttacttcaca tcatatggaa
    17101 caagtcgcta ttgatttgaa aattaacttg atgttttcga aagttggtgt tcctcgtggt
    17161 cgtggaaaaa tagaacgatt ctttcagaca gttaatcaaa ctttcttaga acaactgcct
    17221 ggatatataa acaataatga tactcctagt aatctaataa attttcacaa ttttgaagaa
    17281 aaattacgtt actttttaat tgaagattat aatcaaaaag aacatagtac tattcatacc
    17341 acgcctatca gtcattggaa tagtaatcac tttttcccta atatgccaag tagcttagaa
    17401 caacttgatt tattattgtt ggaaatacct aaatctagaa aagttcattc agatggcatt
    17461 cattttcaag gttttcgata cagtaatact aatctagaag cttatgtagg tgaatatgta
    17521 ctgattcgtt ataacccaaa tgatatggct gaaatacgtg tgttttatag agatgaattt
    17581 ctttgtactg ctatatgtcc agaaatagct gattactcca tagatataaa agacatacag
    17641 cacgctcgta gtcagagaag aaaacactta aaacaaaata ttgctagtcc aagtaccacg
    17701 gaattaatta aggaagaaaa aaattgtggt tattcacctc aagaaacgac taaaaacgtc
    17761 aaaaaattaa agagatatcg taatgactaa aaatcaaaat ttcattgaaa cgaaagagta
    17821 taaacgcttt gctgaatttt gtgatgcttg tattaaatat cagtatattg gtatatgtta
    17881 tggtcaacct ggtgtcggaa aaactttatc gtctaggtat tacacaaatt gggatactat
    17941 tgaaaaacaa gttaaccata gaggttggga agatttagct agtaaaacga ccgatgacat
    18001 actatcggtg gataaaatat tttataatgc accagcagaa aaacaaacta aattaaggaa
    18061 tgatttatat agtattactg caatcattga tttgggtcaa aaattacatg ttgtaaataa
    18121 gtatggacat gaacatagta aacattatag tgatatgttt aaatatattg atttaattat
    18181 agtagatgag attgatcgcc ttaaagtgca acatttagag caattaagag ctatttatga
    18241 tgaacataat ttagcaatga tatttattgg tatgccgggt atagagaaaa aactatctcg
    18301 ttatcctcaa ctatattcgc gtataggttt tgcgcatgaa tttgataatc taagtaaaga
    18361 tgagacgcat catatattag aatataagtg gcaagactta ggatttgatt taaaactcga
    18421 agactttact gattatgagg caataacgac gattattaaa attacaaaag ggaattttag
    18481 gctgattcat cgtttatttg cgcagataga cagaattatg gatataaatg gtttagataa
    18541 aataagtaca gaagttgtag aaacagctag agatagttta gttataggta ttcgataata
    18601 gaaaaagcaa cgcattttaa tatagtgcgt tgcttttctc atttattagg taaagtcatt
    18661 ctcatatatc gagtaaagtg acaacaatta taaaaaaaca acctattcct tcttcttttt
    18721 atgaccctct aaacctaaat aaattaatgt gaaaaccaat gaataaataa aactttctaa
    18781 aaagtcaaaa ggattatcaa ataaaatcga attaacaaaa ttaaaaatta aaaatacaga
    18841 taataaaata atcaaaaagt aaaaaaactt attcatatta aactcctttg tttttatatg
    18901 ttaatattat attgaattca tttaaataac aaaacaaggg ggcatttaca atgaatgcaa
    18961 ttcaaaacag tatatcacta agaaagattt tagtagtatc tttaagtatt ttaaccatac
    19021 tttcaatggt cttggatttt aatttcaaag aagctcaagc ccaaaacaaa aataacattg
    19081 cagataaaaa cgttgaaact ttaaacgaaa aagaaattga aaaagaacta aaatacatat
    19141 atggcaaaat tattatttta gataaagacg gaacagctaa agatgttaat ctagaaaatg
    19201 ccaaatctcg atatggatat gttcctgaag gattccaaaa actaaaaaac gacatagaga
    19261 ataaaaagaa aactagttca atatcaccta gagcagttgg tgggaactac aaaaatagcg
    19321 gtgactgttt ctattctgaa gttttaaact catatggaga acttttaact ggaaacataa
    19381 tcacagcagt ttttgaagat gttaaagcca aaaacttaaa gggcgtagca aaaaaattat
    19441 ctaaaattgg gataaaagga aacctagctg gaatcgcagc tactatggtt tcgaaggatg
    19501 tacaatgtaa tcttaaatac gggttacttt agatactatt tattccaatt gctttattga
    19561 cgttgagcct cggaaccctt aacaatccca aaacttgtcg aatggtcggc ttaatagctc
    19621 acgctatgcc gacattcgtc tgcaagttta gttaagggtt cttctcaaca tcaataaatt
    19681 ttctcggcat aaatgcgtcg tctatttttt attatcttca tgataatcat atttttcttc
    19741 catctcgtca aaagcatcat ctttatagaa aaacaaaaag taagcaacaa caccaatagg
    19801 aataaaaaaa cagtgtgaaa acaagaagaa actcgtttca aaatcccctc aaatattcta
    19861 attattcttt ttgaaattca taaccttaac aaccaaataa atagcattta ttcccatcaa
    19921 aataacatac ggaattaata tatataaatt ttccaaatga gatataaaaa ttaatccaag
    19981 taaaaagaaa acatttaaaa tagttgctat aacgtaacct tcatctaaca ctgtgttttt
    20041 attcaaaata aacactcctt ttttaaaaaa ctttatcaca agacttactc aaattataaa
    20101 tacctttatt ttgagtttta agggggtatt ttaaaggttt agggggtatc atataggttt
    20161 ttaacttaaa aatatataca agctcttaaa acgcaaatat gagccaaata aatatatggt
    20221 aatttcacaa acaaaaattt cagcaaaacc agtgactaat tttttaacac tgcccattta
    20281 catgcaaatt aaaaattagc ataaaatcct ttaaaacttc cacatgtttt tctaaattcc
    20341 tgcagggcgt tttttatcaa aaatcgagaa tttttaattt ttctctaaaa actccgtaag
    20401 agcataagga gaatttgcta tcattcaaaa atgataggtc tggcaaagcc agaaattcca
    20461 ggggttttaa ggtattttaa agtgatatca tacaaagctg tactgtctta tttttgtgac
    20521 acaatatatt gcgtttgtct tatttttgtg acactacata cagcatttgt cacaaaaata
    20581 agacagtact tttttataaa aaatcaacaa aaaagacatt agtcaacact aatgtcttaa
    20641 ataataattt tgcttttcga aattccaaat tgcggtaatt gaatgtgctt tttcttcttc
    20701 gtctgttgtt ttatcttcat cacttgcatt aatcaaatta ccatcttcga catcgtctaa
    20761 gtttaaaatt ttatgttttt gtttaagcaa tccaccataa cttaacatac gttttcgata
    20821 caaacctttt tctaaatcac ttacaatttc ttgatttttt tcatcatcat cagttaaaaa
    20881 atcagatgat ttaaccgaat attttgaggt ctctttgatt gccgattcaa tgtctttatc
    20941 gccttttcta ttcggtttga tcgctttaac attagcaaca ggtcgatagt caacttgtaa
    21001 cgctctttgc cataaattaa cccattcttc ttgagttata taattctctt tttttctaaa
    21061 atatgcattt tcaacacata acaaaacatg catgtgctga ttataactac cgtcattttt
    21121 attaacggta acttctgttg aacgcataaa tccaacaaga ttttgtttaa cctttttata
    21181 tctactcaac ctatcaaatg ctttagttag atgcttcaaa ctttgttcta aagtatctcc
    21241 atctatcgca ttttttgttg aaagtgttaa aaacaaccaa cgtgcttttg gcttttcctt
    21301 aattactttt tcaatcactt tttgagcttg ataactattt ttcatagcac gtctccaatt
    21361 acaaaccgga cataattttg atttacaaaa ccatgtctta tgtaacttca aatagccttc
    21421 atcagttggc ttaaattcta aaatattacc acattgtttt acattaaaag cctttttgat
    21481 ttttaaaatt tctagtatat ctgcatagct tacattatct attttctttt ctctccatgg
    21541 gcgttgtttc ccacttttcg tcatatcttt taacgtttta ttatcttgat tttcggttat
    21601 acttctagta gtattatatt gcatataaaa agacccccag tattatttaa gattcgacac
    21661 cttaataata taactggggt tttttattgt caaattttcc tttcacgcac aaaaacacgt
    21721 ttaaacactg taatatcaac agttacagct atatatataa aatcgagtta tttctatata
    21781 gtatcaagac aagaagaaac tcgttca
//
