LOCUS       NZ_CP089160            21089 bp    DNA     circular CON 13-FEB-2024
DEFINITION  Staphylococcus aureus strain UNC_SaCF18 plasmid unnamed, complete
            sequence.
ACCESSION   NZ_CP089160
VERSION     NZ_CP089160.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN23701158
            Assembly: GCF_021172885.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 21089)
  AUTHORS   Wang,J., Franklin,T. and Wolfgang,M.
  TITLE     NIH Task A24 Option 3 - Murine Chronic Infection Model
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 21089)
  AUTHORS   Wang,J., Franklin,T. and Wolfgang,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) Genetics, University of North Carolina at
            Chapel Hill, 120 Mason Farm Road 5000 D, Genetic Medicine Building
            CB#7264, Chapel Hill, NC 27599, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 27-JUL-2021
            Assembly Method                   :: Flye v. 2.8.3
            Assembly Name                     :: Sa18_genome_20210727
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 72x
            Sequencing Technology             :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/13/2024 04:21:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,987
            CDSs (total)                      :: 2,905
            Genes (coding)                    :: 2,816
            CDSs (with protein)               :: 2,816
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 50 of 89
            Pseudo Genes (incomplete)         :: 44 of 89
            Pseudo Genes (internal stop)      :: 17 of 89
            Pseudo Genes (multiple problems)  :: 21 of 89
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP089160.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..21089
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="UNC_SaCF18"
                     /isolation_source="OP Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed"
                     /geo_loc_name="USA: Chapel Hill, North Carolina"
                     /collection_date="2018-12-04"
     gene            complement(join(20512..21089,1..40))
                     /gene="cadD"
                     /locus_tag="LTK20_RS14800"
                     /old_locus_tag="LTK20_14800"
     ARG             complement(20516..21087)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="93.17"
     gene            complement(1156..1350)
                     /locus_tag="LTK20_RS14805"
                     /old_locus_tag="LTK20_14805"
     CDS             complement(1156..1350)
                     /locus_tag="LTK20_RS14805"
                     /old_locus_tag="LTK20_14805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            1460..2152
                     /locus_tag="LTK20_RS14810"
                     /old_locus_tag="LTK20_14810"
     CDS             1460..2152
                     /locus_tag="LTK20_RS14810"
                     /old_locus_tag="LTK20_14810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            complement(2320..2469)
                     /locus_tag="LTK20_RS14815"
                     /old_locus_tag="LTK20_14815"
     CDS             complement(2320..2469)
                     /locus_tag="LTK20_RS14815"
                     /old_locus_tag="LTK20_14815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(3016..>3305)
                     /locus_tag="LTK20_RS14820"
                     /old_locus_tag="LTK20_14820"
                     /pseudo=""
     CDS             complement(3016..>3305)
                     /locus_tag="LTK20_RS14820"
                     /old_locus_tag="LTK20_14820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(3325..4308)
                     /locus_tag="LTK20_RS14825"
                     /old_locus_tag="LTK20_14825"
     CDS             complement(3325..4308)
                     /locus_tag="LTK20_RS14825"
                     /old_locus_tag="LTK20_14825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            4734..5477
                     /locus_tag="LTK20_RS14830"
                     /old_locus_tag="LTK20_14830"
     CDS             4734..5477
                     /locus_tag="LTK20_RS14830"
                     /old_locus_tag="LTK20_14830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(5704..5889)
                     /locus_tag="LTK20_RS14835"
                     /old_locus_tag="LTK20_14835"
     CDS             complement(5704..5889)
                     /locus_tag="LTK20_RS14835"
                     /old_locus_tag="LTK20_14835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(5894..6232)
                     /locus_tag="LTK20_RS14840"
                     /old_locus_tag="LTK20_14840"
     CDS             complement(5894..6232)
                     /locus_tag="LTK20_RS14840"
                     /old_locus_tag="LTK20_14840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            complement(6478..7086)
                     /locus_tag="LTK20_RS14845"
                     /old_locus_tag="LTK20_14845"
                     /pseudo=""
     CDS             complement(6478..7086)
                     /locus_tag="LTK20_RS14845"
                     /old_locus_tag="LTK20_14845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /name="recombinase family protein"
     gene            complement(7572..8471)
                     /locus_tag="LTK20_RS14850"
                     /old_locus_tag="LTK20_14850"
     CDS             complement(7572..8471)
                     /locus_tag="LTK20_RS14850"
                     /old_locus_tag="LTK20_14850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            complement(8570..10036)
                     /gene="msr(A)"
                     /locus_tag="LTK20_RS14855"
                     /old_locus_tag="LTK20_14855"
     ARG             complement(8574..10036)
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            10760..11434
                     /locus_tag="LTK20_RS14860"
                     /old_locus_tag="LTK20_14860"
     CDS             10760..11434
                     /locus_tag="LTK20_RS14860"
                     /old_locus_tag="LTK20_14860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(11462..11701)
                     /locus_tag="LTK20_RS14865"
                     /old_locus_tag="LTK20_14865"
     CDS             complement(11462..11701)
                     /locus_tag="LTK20_RS14865"
                     /old_locus_tag="LTK20_14865"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_232038637.1"
                     /translation="MQQNQPFNMTVTITKIQALLRRTYDFTTQVNNLTVDDCELLLDAA
                     KLKFNEETIDLTHTELQIMHSLFQKVLLQSKKYS"
                     /name="hypothetical protein"
     gene            complement(11747..12373)
                     /locus_tag="LTK20_RS14870"
                     /old_locus_tag="LTK20_14870"
     CDS             complement(11747..12373)
                     /locus_tag="LTK20_RS14870"
                     /old_locus_tag="LTK20_14870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_232038638.1"
                     /translation="MQQNHLRYVLSYRDISEILRERGVNVHHSTIYRWVQEYAPILYQI
                     WKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWLRKQRDNHSAYAFIKRL
                     IKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLNNLIEQDHRHIKVRKTR
                     YQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIMLAS"
                     /name="IS6 family transposase"
     gene            complement(12420..13094)
                     /locus_tag="LTK20_RS14875"
                     /old_locus_tag="LTK20_14875"
     CDS             complement(12420..13094)
                     /locus_tag="LTK20_RS14875"
                     /old_locus_tag="LTK20_14875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            13356..13541
                     /locus_tag="LTK20_RS14880"
                     /old_locus_tag="LTK20_14880"
     CDS             13356..13541
                     /locus_tag="LTK20_RS14880"
                     /old_locus_tag="LTK20_14880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            complement(13764..14342)
                     /locus_tag="LTK20_RS14885"
                     /old_locus_tag="LTK20_14885"
     CDS             complement(13764..14342)
                     /locus_tag="LTK20_RS14885"
                     /old_locus_tag="LTK20_14885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(14606..14986)
                     /gene="blaI"
                     /locus_tag="LTK20_RS14890"
                     /old_locus_tag="LTK20_14890"
     ARG             complement(14610..14986)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            complement(14976..16733)
                     /gene="blaR1"
                     /locus_tag="LTK20_RS14895"
                     /old_locus_tag="LTK20_14895"
     ARG             complement(14980..16733)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            16840..17685
                     /gene="blaZ"
                     /locus_tag="LTK20_RS14900"
                     /old_locus_tag="LTK20_14900"
     ARG             16841..17682
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(18211..18630)
                     /locus_tag="LTK20_RS14905"
                     /old_locus_tag="LTK20_14905"
     CDS             complement(18211..18630)
                     /locus_tag="LTK20_RS14905"
                     /old_locus_tag="LTK20_14905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            18754..19725
                     /locus_tag="LTK20_RS14910"
                     /old_locus_tag="LTK20_14910"
     CDS             18754..19725
                     /locus_tag="LTK20_RS14910"
                     /old_locus_tag="LTK20_14910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            complement(19897..19989)
                     /locus_tag="LTK20_RS14915"
                     /old_locus_tag="LTK20_14915"
     CDS             complement(19897..19989)
                     /locus_tag="LTK20_RS14915"
                     /old_locus_tag="LTK20_14915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(20146..20493)
                     /locus_tag="LTK20_RS14920"
                     /old_locus_tag="LTK20_14920"
     CDS             complement(20146..20493)
                     /locus_tag="LTK20_RS14920"
                     /old_locus_tag="LTK20_14920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     ARG             complement(7576..8471)
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(8571..10036)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             complement(7573..8471)
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             16841..17685
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          complement(2813..2960)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(3019..3194)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.697"
                     /coverage="94.0"
                     /evalue="1.04e-65"
     Typing          complement(3326..4308)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          4735..5477
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 caatataaag aacagcagca gcaacaaccg tttgaatcat aatacacctc attcaaaaat
       61 atttttgaat gtattataac ttatattttt aaataatcat aggtgcttta ttccaattgc
      121 tttattgacg ttgagcctcg gaacccttaa caatcccaaa acttgtcgaa tggtcggctt
      181 aatagctcac gctatgccga cattcgtctg caagtttagt taagggttct tctcaacatc
      241 aataaatttt ttcggcataa atgcgtgtct atgcgtagac atggagacac ttcagaatta
      301 tggagtgatt acatgagttt aactattttt ctttattcag ttttaggaag tttattagca
      361 aattatatct acgaaaaatc ttcaaaataa ataacttttt cggttctact ttgtacactt
      421 tatctacctg gtagacctaa ttgttattgc tttacaggtc taaaattcgt cgttataatc
      481 tagttaaatc ccgtaagggc gcacttatac gtcggataaa tcgacatgtg caaaaacgta
      541 atcgaccttc gtcgattttt ttatttcaaa attaaagaaa cggcttgaga tattccgagc
      601 agttataaaa attaatttgc gttgaatatt gctactacat tcttgaaaaa gtgatgtaga
      661 tttatagccc ataacttttt tgaattacat cgacgatacg gcgtcgaaag aaaaataaat
      721 agaccgtatg aaagaaaaag ctacctcact ttatctgggg tagcttttat tttttatgcc
      781 cttattttga attttaagag ggcattttaa agatttaggg gtgattcata tagttttata
      841 tctaaaactt atatatgctt ttaaaacgca aatatgagcc aaataaatat atgctatttt
      901 caaaaacaaa aatttgagca aaaacaataa ctatttttag acactgccca tttacatgca
      961 aattaaaaat tagcataaaa ttctttaaaa cttccccacg tttttctaaa ttcctgtagg
     1021 gcgtttttat caaaaatcaa gacaagaaga aactcgttca cactcgtttc aaaaaaacaa
     1081 gaaatctaat ctatacacct accgttttcc aaccccctca aagcatacaa attaaaaaca
     1141 aaattattca taatcttact ttcttttaac aaaaacataa aaaccataaa tagacaaatt
     1201 aactatcaaa ggcaataaac agtataaaaa aaccacgaat aaatcttcat caacatctaa
     1261 aataaaaaag aataaaacaa ttaacaaaat actaattaac aaacctaaaa gtggcaaact
     1321 ttttatatat ttttctaaat tttcattcat aaaatagact cctttcaaaa atatgtttat
     1381 aaatatatta aaataaatat tgattttata aagcgcttac ttatacaatt aaaatatctt
     1441 attatcttgg aggtatcaaa tgaaaattat aaaattattt tcaataattt ccttgttcct
     1501 actggtattt agcgcgaatt tttctaatgc ttacgcaaat gaagaacaaa aaagttcttt
     1561 actagaaaat caaaaagaaa aattgaaaag caaaaacatc gaagtatcac aaatgaccaa
     1621 gaaagaaata agttttctag aacaattgca aaataaaaat gaagatatgc aaaaattcga
     1681 aaagcaaatg aaaaaagaag gatttaaaaa aataaagcta gaagacaaaa attctaaatt
     1741 aaaatatcta gctacagaag caaatgataa aaatgcatat ggctacatag ctaataacgc
     1801 ttataaaaat gaaaaaacaa aagaaattgt agtttctgaa acaatatatg ataactacaa
     1861 caaaaaaatc acaaaattca ttgccgaaaa aagaagtatg actgaaaaca aagagggaaa
     1921 aatacttatt aacaaaaatt acgttgaata taaggctgaa aaagttgata aaaacagacc
     1981 ggtaacatat gcaggattca aatggaacgg caaagcattc gcttgtagta tggctggact
     2041 ttatgcatgt gctcactact gtggagtatg ggcaatcgta aatccaatag ccggcggtgt
     2101 atgtgaagca gtttgcggaa ctgcatttgc agctggatgc tctgtaggtt gattttattc
     2161 caattgtttt attgacgttg agcctcggaa cccttaacaa tcccaaaact tgtcgaatgg
     2221 tcggcttaat agctcacgct atgccgacat tcgtctgcaa gtttagttaa gggttcttct
     2281 caacatcaat aaattttttc ggcataaata cgatgttcct tatttatcct cataaaaaac
     2341 aatagctgaa atatataacc aattactgtg tgtttgaatt tctaatacat gaatatcatt
     2401 ctttaaaaac ctattaactt gtttatctaa ttgacgatga gtaaaagtag cgaaagtttt
     2461 aatcttcatg atatctctcc ttttataaaa atagcaatcc ttattacaat attaaacact
     2521 tttattttgg attttaagag gcattttgaa gacttagagg caaatcatat aggttttgta
     2581 cttaaaaatc tatacagtct cttaaaacgc aaatatgagc caaataaata tatgctaatt
     2641 tcacaaacaa aaatttcagc aaaatcagtg actaattttt tagatactgc ccatttacat
     2701 gcaaatttaa aaattagcat aaaatacttt aaaacttccc catgtttttc taaattcctg
     2761 cagggctttt cttatcaaaa acttagaaat tttaatttaa ctctaaaatc tccgtaagag
     2821 cataagggaa atttgctatc attcaaaaat gatagatctg gcaaggccag acattccaag
     2881 ggttttaagt tattttaaag tgatatcata caaagctgta gtgtcacact tttgtgacac
     2941 tacatacagc atttgtcaca aaaataagac agcacttttt tacagaaaaa caataaaaaa
     3001 agacatcagt tatcactaat gtcttaaata ataattttgc ttttcgaaat tccaaattgc
     3061 ggtaattgaa tgtgcttttt ttcttcgtct gtcgttttat cttcatcact tgtattaatc
     3121 aaattaccat cttcggcatc gtctaagttt aaaattttat gcttttgttt aagcaatcca
     3181 ccataactta acatacgttt tcgatacaaa cctttttcta aatcacttac aatttcttga
     3241 tttttttcgt cgtcatcagt taaaaagtca gatgatttaa cggaatattt tgatgtctct
     3301 tcgagtgtta taaaatcatt tgaattattg attaaagata ttatattgtt tcatgttttt
     3361 acggcgcata taaagggcat gtgtttcttc aagttcagtt agaattgttt gcattaaata
     3421 agcttgcatt gacttgattg tttccttttg gcctttaact cccctatcat gtatagcttt
     3481 tttaagtctt tttaaagaag ttaatatttc atcctcaatg tcctctaaca tgtaatgcat
     3541 atcttcatgc cttgaattaa atgatttttt tgctttaaga ataacagcct ttatgatttc
     3601 taaatctcta taatcatatt ttaataaata attagttagt tgttctggga attcttgcaa
     3661 tagcatttct ttatcatcaa aattatgtgt aaattgattt gaatgatttg aatgattact
     3721 aatttcattt ttgtacttta tatcattcaa gtcattcata tcattattct cagtatcatt
     3781 aaagtcaatg tcattaaagt cagtatcatt agtgttcgat tttcgaactt ctggacgttc
     3841 gattttcgaa cttctggacg ttcgattttc gaacttctgg acgttcgatt ttcgaacttc
     3901 cttctcgccg taaggttcaa catcgttttc ttctttttct attttgtaaa tatcacgttc
     3961 tgtgacaata ggtttcatta aatatagaat atttggttta tttaaaccac gtcgtttttg
     4021 aatgagtaga ccatcgtttt ctaacccttt ttttattttt gttaactttt cttttttaca
     4081 atttaagatt tccattagct tttcatttga ataaacaaag taaatgttac catcttcatc
     4141 aacccagcta tttttaatag ataaatttaa gcgatcacgt aagatagcat aggctatttt
     4201 catatcatta gttagatttt tataattttc actggtaaag aatactttag ggatttgata
     4261 aaatctttct ttgtaatttt cttgcactgt aaaatattga ttttgcatga caaaaaacct
     4321 ctttccatat tttagtttgg taagaggtaa taaaacgttt ttatttagct ttacatttat
     4381 ttaatgattt aggtgcttgc actaagatat tattcattat ataatacaag tatcgaaaat
     4441 tatataaata aacagtttct aaacgtttta ttaccaaacc ccgactatta ccagtagttg
     4501 gggtttttgt tatattaagt ttattatagc actttaaata aacttataaa agggaaaata
     4561 tagctttatc aagggtttat aaacccttga taaatatcat aaacctttca taaacccttg
     4621 ataaaaaggt tgatggatgt ttatttttat ttattaatca ctttattatt aagcattata
     4681 agcttataat attttatcaa gggtttataa acattttata aagggttgat gatatgaaaa
     4741 gtgtgaaaaa gttgagtgaa gaattagggg ttagtaagca aacgattttt aataatatta
     4801 agcgattgaa tatagagaca ataaaacagg aaaacacttc gtttattaaa gaagataccg
     4861 atatagaaaa aatcattcaa agagtaaatg aaaataaaaa gaaatatggt tttgaaagta
     4921 ctactgaaga caaacaaaaa aaagggtcgg ataatattaa ttttgaatcg aaaagcgatg
     4981 ctcaaatagt agaaatcctt aaaaatcaga ttgatacttt aaataatcaa attgaaaaac
     5041 aagaaagtcg tcatgaaaca acaattgaat tttacagaaa agagttgcaa gaaagatcaa
     5101 aattgcttga aaatcagcaa gttctggcat tagagagtaa taaaaagatt caaaaattag
     5161 aaaatcaatt agaaaaagaa aaacacctta attatccctt tgatacatct actaacacta
     5221 gacaaaacgt tgatgcacaa gaaaaaacat atactactaa tcctgtaaat attaacagag
     5281 atcaggaaga aactaaagaa acagagattc aatataagga tatatctgga agtcaaagcg
     5341 acgaaagtac acaaggtgaa gaagcaaaaa aagaagacgt tccagctaat ctaaatgaca
     5401 atgatagtga tatagaagaa aagagtgaag aaacggaacc taaaaagggg ttttggagtc
     5461 gtttgtttgg tagctaaaat aattgattag gcactaaaag ttataaaatt ttagtgtctt
     5521 ttatatagtg agaacttctg gtaatcatcg attatgtaaa ctaaagtatt tcaaataatt
     5581 aactgtatta atactctcat catgattgcg ttataaacgt tcgttattga gacaaaattt
     5641 aatagtacta ctacacaaaa agagagtgcg aattcgcact ctctttttgt gataaatgaa
     5701 tggttaagaa aataattcat ccacagttgt atcaaacaat cttgccaact taaatgctaa
     5761 tgtcaatgta ggatcatatt tattgttttc tattgcatta atagtttgcc tagacacttt
     5821 taattcttta cttaaagttt cttgagaaat tcctttttgt tttctatatt ctctaattct
     5881 atttttcatt aatttaacct ttagatgtat attttttatt tgtagtatag taattaaaca
     5941 gcataagaaa tagtgctaca attataaaga aaatttctgg atattgagaa aaccaagatc
     6001 cttcaatact tggtgacaaa cctgtaaatt taagcactag tgtaaataac atacaatata
     6061 caatccaaat aaaactttta gccagtattt caataaacat tttacgttgt ctttcatcgt
     6121 atcgatcttg ttgtcctttt ttatctaatg tttctgaagg taaatatttg ttagttatag
     6181 ccgtccataa acaagaaaaa attaaaataa taataaaagg aattaaattc attataacac
     6241 ctcataaatg taaaaagtat ttgacattta tgagtgtaaa tatttttgat acaaatgtca
     6301 aatacttttt acattataat atattttaaa acaccttatt agtaaaacaa ttactatata
     6361 gaaagctgcg aactcgtact cttttttctt gtataattat taaaatctca attcaataat
     6421 atgttatgga atttgagaca ctgtgagaga cgctcatttg cattgacaat caatttatca
     6481 agataatccc ttatcatgtt taattctata aactgtttgt cttgtgatat taacttcttt
     6541 cgcaatctta ctaatcgctt tgccttcttc taacatttcc accacgcgat gataaataac
     6601 acgtttctgt gggtctttag catttggtga ataaagtaaa gggcgccctt tatatacgcc
     6661 tttttccttc gcaacttgaa tcccttgcgc ttgtcgacgt ttactttcat ttctctcttg
     6721 ttctgaaacc attgctaata tttgaatgat taaatctttc ataaacttat ccagtaatgg
     6781 attgccaatt acttcattca tcataggtaa gctggtaatc attaactgaa cgtctttttc
     6841 ttttaaataa ttcacagttt caataatttc atcatagtta cgtcctaaac gatcaataga
     6901 ttccacaacg aatcgatctc ccattctgac aaaattgagt gcttattgaa atacaggtct
     6961 attttccact gactttcccg actgtttctc tgtaaagatt ttctccacac caaacgtctt
     7021 taaattatcc aattgtcttt ctaaattttg atctatcgat gatactctcg cataacctat
     7081 aatcattcat cttcactcca taataaatat acaccctaat catacgtttt aattgttata
     7141 atttcaacaa ttctttttgt atggttaggg tgtactcaaa gtgtacatat ctataattaa
     7201 aacttactaa aaataaatat agattttttc tttgtaacag aaccgttcat ttgaaggtca
     7261 tctctatcat aaatatttaa attaactaaa aattttaatc atctgtttaa tacttatgaa
     7321 atgtatttac ggtaggtatt aaaattgatg aaatttatat aagtgctttc aatgaaaatg
     7381 accgtttatt tatcctcctg atttaaggag ttagaaattt cgaaaacgat tctttccatt
     7441 tgttgcattt gttccatgtc cagatattta atacattata gaaaaccaaa gaccatcact
     7501 aattaaacgc agttttaaaa tttcatcagg attgccttcg tctttaaaat gggcctcttt
     7561 taatataagt tctactcttt catacctaac tctttcaatg ccatcgtttc atacgccgat
     7621 tctcctgatt ccatagcaaa ctcagcgata aacattggga atactgcatt gagttctatt
     7681 atatgctctt tcattcgtgg ccatatttca cctccagctt taccgtatgc tgttataagt
     7741 tgctctaatc cttcgtcgtc gaatacacga tggtgtccta taaagtccat tgatgggtcg
     7801 gagtgggttg cttcagtcca gtctatgaga cctgtgacgt ttgcttggtt atctaccatt
     7861 atatgtcctg gatgtaagtc cccatgtatc atggtcgcat gtcgaggcca tagttcgtcg
     7921 ttttctaacc attgtttcca tctgttccat aattcatctg atacgccata agtttcttta
     7981 actttattca ttcttctttg aaagtcattt tttatttctt gtatggtttt gatatttata
     8041 tgctgaacgt taatgttttc ttctggtatg ttgtgtaaat ctacgagtgt ttcagctaat
     8101 gtgttaataa agttttctgg taatggtttg tgttcaattt cccatacata attttgtatt
     8161 tctggatcta ttgtggctgc gggtttacct gtaagttttg ggtaagcaat aaggtctttt
     8221 gcatgtactt tccacttcgg tatttcaaat gaaacattct tctgtaagaa gtctaccgtt
     8281 tgtttttcgg gttttgttcg tttataaacg tcaggtcttc ttggtagtct caaaacccat
     8341 tctactccat gtttatcttt tccaaatgca acttgaaaat caagtcccga ttcattcaat
     8401 gagattgttt gaggttggat gtgtaattga tatttttctg cacatttaat aatttcatta
     8461 tgtcgagtca ttttattgga tccttatttc tattatattt ttcttgtgaa cgtatttttt
     8521 atattgatat aaatgaacct aatattcaat ataaattagt gtatagtttt taagttatat
     8581 catgaagaga ttgtcctgtt aattcccatt ttttatctga tacatgttta acaaaccttg
     8641 tatcatgtga tgtaaacaaa atgattccag gatatttatt cataaacatt tctaatgctt
     8701 ctaatgtttt aatatctaaa aaattagttg gttcatccaa aattaacata ttcgctttcg
     8761 ttgaaaataa tactgctaac gataatttcg ttctttcccc accactcaaa acattacaag
     8821 aacgatcaag tgcttcattt aaacccaagt tatttaaaat agctctactg aatgattctg
     8881 atgaatccgt ttcatccatt aaatattgca ataatgaaac gtcacgcatg tcttcataag
     8941 caagttgacg atagtatgcc atttgcactt taggagaaca atcaattccc tctatttggt
     9001 ggtaaatagc ttcaagtaaa gttgtcttac ctacaccatt tgcacctacg agcgctatat
     9061 ttttgccata tggtatttgg aatcgtactt gtgttagcag tttttgactt cctttaacca
     9121 atgttagatt ttgtgcaatg attggataat tattatggat atcataaatt ttattttgtg
     9181 ggaaattgaa ttcatgataa ctttgtggtt tttcaacttc ttccaaatgt tccattcttt
     9241 tttcaatatg cttagcttgt ttttgagcag ccttctcaac cgtgcctttt tgttttgatg
     9301 cacttaaacg atctggtgct atacttttgt ttttttgttt tgatgatgct tgtgccattt
     9361 gttgcgcttg atttcgttta gctttactgg cttgggacaa tctttgtttt tcacttatat
     9421 actgttcata ttgacgttgt tgttctaact gttcttgttc atattgattt tgatactgtg
     9481 tgtaattacc tttaaacact cttattgtgc catcttcttg tatatcccaa attgtgtcag
     9541 caatttggtc tataagtgct ctatcatgac ttactataat taaagtacca tagtaatatt
     9601 ttaaaatatt tttcagataa tctttaccaa ttttatccaa gtgatttgta ggttcatcta
     9661 aaagtaatat cggactataa tttgatatga cattagctaa tttatatttt gctttttcac
     9721 caccactcat actgtcggtt gtatgcatag gtatatggag ttcactcatt aaactaccgt
     9781 ctaacgtgtt aaaatcattt tccacatcca tgttaagctg ttcaaaatat tgaatttcgc
     9841 caaccgtttc aactgttcca gattctggtt ttgttttttg agcaatcata tttagtaatg
     9901 tggttttgcc agtaccatta cccccaataa gtgctatttt ttcaaattgg taagcgtaaa
     9961 gatgaccgat gttaagtgat cgtaaatctg tcaatttatg attgatttgg ttaaatttaa
    10021 ttgtatattg ttccatattt atacactcct tgtatattta aaggacgtgt acgcaaaaaa
    10081 atgagacagg ctactcccgt ctcattcaca ttacactttc aaacacttaa aaatttatta
    10141 tgatgtttta gtatttgaaa gcgtttatta ttcctatcga aggataaaaa atgacataag
    10201 tcatcctatg agtgtgtatt gcggacaagc ctttttgaat taatttagtt ttgtattcaa
    10261 aaaggtttat ttgagtctca tagaagctgt cattttaatc ctccttcatc gataaaatag
    10321 taatgttaat ataacatttt gttggttttt ttacaatata tctctaagta gaaagattat
    10381 ataacaaaag tataaaaata caattttaga ttgattatac atctccttaa tttagagtgt
    10441 actcataaaa tacggttctg ttgcaaagtt gaatttataa tataatttta acaaaaagga
    10501 gtcttctgta tgaactattt cagatataaa caatttaaca aggatgttat cactgtagcc
    10561 gttggctact atctaagagg ttctgttgca aagttgaatt tatagtataa ttttaacaaa
    10621 aaggagtctt ctgtatgaac tatttcagat ataaacaatt taacaaggat gttatcactg
    10681 tagccgttgg ctactatcta agaggttctg ttgcaaagtt gaatttatag tataatttta
    10741 acaaaaagga gtcttctgta tgaactattt cagatataaa caatttaaca aggatgttat
    10801 cactgtagct gttggctact atctaagata tgcattgagt tatcgtgata tatctgaaat
    10861 attaagggaa cgtggtgtaa acgttcatca ttcaacggtc taccgttggg ttcaagaata
    10921 tgccccaatt ttatatcaaa tttggaagaa aaagcataaa aaagcttatt acaaatggcg
    10981 tattgatgag acgtacatca aaataaaagg aaaatggagc tatttatatc gtgccattga
    11041 tgcagaggga catacattag atatttggtt gcgtaagcaa cgagataatc attcagcata
    11101 tgcgtttatc aaacgtctca ttaaacaatt tggtaaacct caaaaggtaa ttacagatca
    11161 ggcaccttca acgaaggtag caatggttaa agtaattaaa gcttttaaac ttaaacctga
    11221 ctgccattgt acatcgaaat atctgaataa cctcattgag caagatcacc gtcatattaa
    11281 agtaagaaag acaaggtatc aaagtatcaa tacagcaaag aatactttaa aaggtattga
    11341 gtgtatttac gctctatata aaaagaaccg caggtctctt cagatctacg gattttcgcc
    11401 atgccacgaa attagcatca tgctagcaag ttaagcgaac actgacatga taaattagtg
    11461 gttagctata ttttttactt tgcaacagaa ccttctggaa taagctatgc atgatttgca
    11521 attcagtgtg tgtcaggtct atggtttctt cattaaattt aagctttgct gcatcaagta
    11581 gtaactcgca atcatctact gttaaattat taacttgagt ggtgaaatca tacgtgcggc
    11641 gtaatagtgc ttgaatctta gtaattgtaa cagtcatatt aaatggctgg ttctgttgca
    11701 aagtaaaaaa tatagctaat cactaatata tcatgtcagt gttcgtttaa cttgctagca
    11761 tgatgctaat ttcgtggcat ggggaaaatc cgtagatctg aagagaccta cggttctttt
    11821 tatatagagc gtaaatacat tcaatacctt ttaaagtatt ctttgccgta ttgatacttt
    11881 gatatcttgt ctttcttact ttaatatgac ggtgatcttg ctcaatgagg ttattcagat
    11941 atttcgatgt acaatgacag tcaggtttaa gtttaaaagc tttaattatt ttagccattg
    12001 ctgccttcgt tgaaggtgcc tgatctgtaa ctaccttttg aggcttacca aattgtttaa
    12061 tgagacgttt gataaacgca tatgctgaat gattatctcg ttgcttacgc aaccaaatat
    12121 ctaatgtatg tccctctgta tcaatggcac gatataaata gctccatttt ccttttattt
    12181 tgatatacgt ctcatcaata cgccatttgt aataagcttt tttatgcttt ttcttccaaa
    12241 tttgatataa aattggggca tattcttgaa cccaacggta gatcgttgaa tgatgaacgt
    12301 ttacaccacg ttctcttaat atttcagata tatcacgata gctcaataca tatcttagat
    12361 ggttctgttg caaagtaaaa aaatatagct aaccactaat ttatcatgtc agtgttcgct
    12421 taacttgcta gcatgatgct aatttcgtgg catggcgaaa atccgtagat ctgaagagac
    12481 ctgcggttct ttttatatag agcgtaaata cactcaatac cttttaaagt attctttgct
    12541 gtattgatac tttgatacct tgtctttctt actttaatat gacggtgatc ttgctcaatg
    12601 aggttattca gatatttcga tgtacaatgg cagtcaggtt taagtttaaa agctttaatt
    12661 actttaacca ttgctacctt cgttgaaggt gcctgatctg taattacctt ttgaggttta
    12721 ccaaattgtt taatgagacg tttgataaac gcatatgctg aatgattatc tcgttgctta
    12781 cgcaaccaaa tatctaatgt atgtccctct gcatcaatgg cacgatataa atagctccat
    12841 tttcctttta ttttgatgta cgtctcatca atacgccatt tgtaataagc ttttttatgc
    12901 tttttcttcc aaatttgata taaaattggg gcatattctt gaacccaacg gtagaccgtt
    12961 gaatgatgaa cgtttacacc acgttccctt aatatttcag atatatcacg ataactcaat
    13021 gcatatctta gatagtagcc aacagctaca gtgataacat ccttgttaaa ttgtttatat
    13081 ctgaaatagt tcatacagaa gactcctttt tgttaaaatt atactataaa ttcaactttg
    13141 caacagaacc tcatttacta tatgggcatc tctttcatta ttaatacaaa gctttgtatc
    13201 tccgatatta ggcaaaggtg taaacgaatt aggtgatact ataggattca acattatatt
    13261 aatcgtttct ttaataatga ttatcttctt attttttata aatcgtagta aaaatatctc
    13321 ctatgattat ataaaagttc aaagaggtga agccaatgaa taaattagaa aaatggtctt
    13381 tggtatttat tatttttaca tttctctctt cattagcact tttatatttc aaatataatt
    13441 ttagttcggt tatgccagtc ctaagtcttt ctattttaac tatactaata ttgttgacga
    13501 gtattattac tgtagtttca gttaatgatg aagatactta aaacgttcat tagtgaaaca
    13561 ggtattatat taaaaaagcg tacgaatttg tacgcttttt tcttgtgtta ttattaaaat
    13621 ctcataacag gaaaatatta tgagatttta gacgctgtca gaacgtctct tttacatcga
    13681 gtgacattga atcaaagtct ttgtatgtta atgatatata aaattattta gtagattcat
    13741 tatagtaagc tagattagtt gctctacttg tttttattct cttttgcctc taatttattg
    13801 agataacgat aaatagttgt acgtgaaact tgccactgct ctgcaattgt tttaattggc
    13861 gtaccattat cataaagtgt cttaagtaag tttaaatctt gtttatttaa tttttcaggt
    13921 ctacctccat atcggcctct agcacgtgct gcaattcgac cggctgatga tcgctctaaa
    13981 attaaattac gttcaaactc tgcaaatgct gcgaataaat gaaataataa ttgtcctgta
    14041 gaacttgatt tatccatcgt tatattttct tctaaactat gaaaactcac acctcgttcg
    14101 ttaagttcat taactaacgt gattaaatcc tccatgttcc gtcctagtct atctaatctc
    14161 caaacaacaa tcgtatctcc tgacctcgca aattcaattg ctttatctaa accaggtcgc
    14221 ttactttttg aaccactcat atggtcatta aatatctttt cacaaccata tgtatttaat
    14281 cgatcctcct gtaaattcaa attttgtaat ccagttgaaa ctcttgcata acctattttc
    14341 aaaatacaga cctcctatat acacctttag tgtaccataa cttgattacg aggtcttttg
    14401 tgaacataga ttttttgttg ggtttttgaa cacataattc tatgtaatac ttacttattt
    14461 agacaaaaaa caagagtgta cagaaaatgg ttattttctg gacactctca tctttaataa
    14521 tatattttaa atgtcattaa caaaactaat ttaataagag tcaagtatgg tttacatatg
    14581 tattatgttt gaaacatacc tctaattact ttttactaat atcatttaaa atgtctcgca
    14641 attcttcaat ttctttgtta tttaattctt catttttcgc aaaattcagc actaaacttt
    14701 tcatatcccc tccatacagt ttattaagaa aggttttagc agttttcatt ttaatatcgt
    14761 cttctttaat atttgatgag taaaaataaa tattttctga tttgtatcgt tttataatct
    14821 cttttttata tagtcttgtg attaatgttc taatcgtttt atcactaact tctttatatt
    14881 tttgaatttc aactacaatt tcattagctg atactgattt tttatcccat attatattca
    14941 taacatccca ttcagccata gatatttcaa cttgcttatt ggtcatttaa aacacccatt
    15001 ccttttaata ttttttcact tattaattca gcatttttcc cagacgggtt tccatctgat
    15061 aaatgtgtag caaaataata cttatcatga tttgtaatta cgtaacctac aaaccaccca
    15121 ttattatact tcccgtttac tatacctgta cctgttttcc catacagttc atacttttca
    15181 tttttcttaa tcaataatga agaagataat tgattctttg cttttttact aaaatggtta
    15241 ttttgttcca tcatattttt aaaaactatt acttgttcaa gattagatat tttcaaacta
    15301 tcttccatcc aatagctttt ataacttccc aaattttcat taccataatt taattgcttg
    15361 agttgagccg cagtatagtt ctttggtatt tgattactaa tacgttcgaa gtaccaatta
    15421 actgaatttt gcattgctgt atttaaatct tgttccttat tccaagactc gaaaagataa
    15481 tgtttatgat tccatgacat acgtgaattt ttatcactta taatatgacg gtcaagtcca
    15541 aacagtgcta aataaatttt gtaagttgaa tcaggagaat atctttttct actttctttt
    15601 tcattataaa tatagtattt gtctttcttc atgctgtaca taacgaaaga tccactattt
    15661 gaaccaaaat ttttactttc atctaaaatt tggtaatcgc tttgtaaggg ctttttataa
    15721 ttataatcag ttaaggattg ccccattaaa aactggcttt gaattatcat gataaaaaaa
    15781 gtaaaaatac aaataaaaat tagaattaat tttgactgct ttttcagatc ggcttctttt
    15841 atattaatta atctactttt gagtaatgat tttttaccat taaatgaatg gcttaatata
    15901 tttttgttgg aaaatggggt ttttaatacg gagtccataa tagattccgc ataagtttta
    15961 aattcatttt tgttaatatt attaaggaca aatctatcgg cttctacttc attgtcatga
    16021 attatctttc tttttacaat atgtactaat ggattgtaac tcataataat agagaagata
    16081 ttaaagataa ttaaatgtaa agtatctcta tttttagcat gagcatattc atgcagtatt
    16141 atatatttta gtcttttatc aattacactt ttaaaatatg aactaggaat caaaataata
    16201 tatttcccat accaaaaagt tattggagat tgaatagcct ctgcttttcg aatcacaata
    16261 ttttttttat attgatggtt gaaaagtatc gtatctattt tatttttttc attttcgttt
    16321 agataaagtg actgtttctt taaatattta agatataata aggctttcaa aaatttaaaa
    16381 cttaaaataa taactaaaac tatccaaata actgtgcaga tattatcaat tgaatcccaa
    16441 ttaaacttat ggatatctgt tgtgaactct tgaataggtt tggtggtatt tatgttatgg
    16501 ttcaaatcgt gtgacttact ttcaactgtg ggcgcttgat tattcacatt attaaatttt
    16561 ataaaagaga atttaattgg gataaaagga attaatccag caagcatagt tagataccaa
    16621 actttataat ttaaactata attaaaatag cgttttaata tgtacctaaa aaatactaac
    16681 aatagaaata taaaacaaaa gcttactacg ctcattatta gtaatttagc cattttgaca
    16741 ccttctttca aatatttata ataaacaatt gacatcaata ttacaattgt aatattattg
    16801 atttataaaa attacaactg taatatcgga gggtttattt tgaaaaagtt aatattttta
    16861 attgtaattg ctttagtttt aagtgcatgt aattcaaaca gttcacatgc caaagagtta
    16921 aatgatttag aaaaaaaata taatgctcat attggtgttt atgctttaaa tactaaaagt
    16981 ggtaaggaag taaaatttaa ttcagataag agatttgcct atgcttcgac ttcaaaagcg
    17041 ataaatagtg ctattttgtt agaacaagta ccttataata agttaaataa aaaagtacat
    17101 attaacaaag atgatatagt tgcttattct cctattttag aaaaatatgt aggaaaagat
    17161 atcactttaa aagaacttat tgaggcttca atgacatata gtgataatac agcaaacaat
    17221 aaaattataa aagaaatcgg tggaatcaaa aaagttaaac aacgtctaaa agaactagga
    17281 gataaagtaa caaatccagt tagatatgag atagaattaa attactattc accaaagagc
    17341 aaaaaagata cttcaacgcc tgctgctttc ggcaagactt taaataaact tatcgcaaat
    17401 ggaaaattaa gcaaaaaaaa taaaaatttc ttacttgatt taatgtttaa taataaaaac
    17461 ggagacactt taattaaaga tggtgttcca aaagactata aggttgctga taaaagtggt
    17521 caagcaataa catatgcttc tagaaatgat gttgcttttg tttatcctaa gggccaatct
    17581 gaacctattg ttttagtcat ttttacgaat aaagacaata aaagtgataa gccaaatgat
    17641 aagttgataa gtgaaaccgc caagagtgta atgaaggaat tttaatattc taaatgcata
    17701 ataaatactg ataacatctt atagtttgta ttatattttg tattatcgtt gacatgtata
    17761 attttgatat caaaaactga ttttcccttt attattttcg agatttattt tcttaattct
    17821 ctttaacaaa ctagaaatat tgtatataca aaaaatcata aataatagat gaatagttta
    17881 attataggtg ttcatcaatc gaaaaagcaa cgtatcttat ttaaagtgcg ttgctttttt
    17941 ctcatttata aggttaaata attctcatat atcaagcaaa gtgacaatag cattttacaa
    18001 gtatttttta ttgttcgatt agggtaaacc taaataatac ataaattata ttacaatatg
    18061 tttattatag aggctaaagt atcttagaaa tttggatagt aggtttttcg ggaataaaag
    18121 tatagttggc tttaatatat aattaagcta agctatcatt tatatttact cgattataat
    18181 tcgcacttca acttttttat aacgtaaaaa ttaaaacgta gttttattta tctttagtaa
    18241 tatcttttta aacactacag tttcttcatt agttaaatta gcgaagtaat gattattaag
    18301 ttgataggct ttcttttcta atgttggcca taagtctttt gctttatttg tactgtttat
    18361 tagcacagtt cttctatttt cattatcagt ttgacgtgtt attagatcct ttttggacat
    18421 cttatctaat attccagata ttgttgaagg ttctaaattt aaagtattac caatcgcttt
    18481 aggtgtattc aaattactat taatcaagca attcaaaaca ccatattctg ctggagtaat
    18541 attataggga cttaataaac ttttaaaatg tttaaaaact ctattctgag aagtactcaa
    18601 caaataattt atacaattat ctaattccac aactaaaacc tctcttaaat cattagtatt
    18661 gactcgctta tcatatcatg ataagttttg taggaaaata gttttgcaac aaaaacatac
    18721 ttctacaaaa caattgtgaa agaaggctaa taaatgttca atgcggtagt agtgagaaaa
    18781 agtgcatcaa atgttagtta taaagtagaa aaagttgatg aatctcattt atcgaagggt
    18841 gatgtattag taaaagtggt atactcttca ataaattata aggatatgct agctttacaa
    18901 tataaaggcg gtgtaattag agattatcct atgattcctg gtatagattt tgcaggtatt
    18961 gttgaatcaa gttcgaatga taagtttaaa gaaggcgata atgtattagt tactggttat
    19021 gatgttggcg tgacacatac aggtggattt tcagaatatg cacaagtgcc tggagagtgg
    19081 attgttccta ttccccaaga aatgtctatt aaagagtcta tggtatatgg cacagccggt
    19141 tttacggcag cattatcaat ttttgaacta gaaaaatatg gaatgaatat caaatcacaa
    19201 cctgaaattt tagtgtctgg ggctacaggt ggtgtgggca gtgttgctat acaaatttta
    19261 cataaaattg gatatgaaaa tatcactgct atcgtaagaa aagaaaagca aatagaaatc
    19321 gcaaaaaaat taggtgcaaa acaagtaata ataattgaag atgataataa accgcttaaa
    19381 aaaggtattt ttgattattt cttagataca gtggggagta atgtaacatt atacggttta
    19441 aaacgtctaa attatcaagg tgttgctact gtatgtggaa atgtagcagg aaattcactt
    19501 aacgctaata tattaccgtt tattcttaga ggtattaaat taattggcat tgattctgta
    19561 tatgttgatc ataatatccg tgaagatata tggagtaagt tagcaaatga atggaatata
    19621 ggaaattcac ttctatacaa tgaaattgga tttgaagaat tctataaaac gatagatcag
    19681 cttttaaaag gacaacattt aggaagaact attttaaaag tataagtgtg agtattcatt
    19741 aatacattta ctattaattc aatcattttg catttctcta ctaaccagtg ttataattta
    19801 tataacgaaa atgattaaca attaatgcac caatccccac actattgcag tagtgtgggg
    19861 attttttcga tgctggctta taaagtcgcc tattaattat ttgttgcgtt tactaagcca
    19921 ataagtataa tacgcaacag cacagccact gatgactggt gctatgatgt gaacgaaaat
    19981 gattagcaaa gtaatgcacc tcctctcttc gtcaattgac gcctgagaga taggcgactc
    20041 tattattata ccatctgtga atatacaagc atatctactt ccgataagtc gtcttatgtt
    20101 atataacttt gttttttata gtatcaagac aagaagaaac tcgtttcaaa aaccctcatg
    20161 atttttagag aaaaactctc ttatttcatc gtctttaata aaataatatg ccatctttcc
    20221 atctttataa aaatcaagta cctcattttt atataaaagc cttaaatgat gtgaagttga
    20281 agcaacactc attttcaata tcaaagaaat atcacaaaca cacaactcat cttctttaat
    20341 caaagataat atgattttca atttcttctc atcacaaatt ttttctaaaa tgttaagtaa
    20401 tttcttagat ttatcatctt ctaaaaaact taaagcattg ttaactttat cctcatgtac
    20461 acagatcaca tcacaagtat tttcataact catataaaat cacaccctaa attaaaatat
    20521 aaatcctaaa attgtttgaa tagtgtcatt ttcaataata ataaataaac ctaaagctat
    20581 ataaataata gccataatcc aacgactaaa tttctcaaca atttctccaa ttcctggaat
    20641 attagctaat ttttgtgcag taaacaccaa gaagaaaatt aaaattaaaa agacaaacag
    20701 agtaagtaat aaattagtaa cacttaatgt cacaaaatac ggaacaaata aaccaatatt
    20761 atcggcgcca caacttgcta tcgtaacaat tgcaaccgta ccaactaatt tagacaatcc
    20821 tttttcattc aattcttttt tagctctctt ttctccttca caatcatcat aaatagccac
    20881 tttaattcca agataaattg gtattaaacc caataaacct aatatccact tttctggaac
    20941 ataatttaat acaaaagcta aaaacaaact aactaatatt aaaataatag accctaaata
    21001 ttgaccaaca taaatatctc tatattcttt tctagtcttt gctctagcaa aaaatattaa
    21061 taaaattact aataaatcaa ctgctgtag
//
