LOCUS       NZ_CP088193            30822 bp    DNA     circular CON 21-MAY-2024
DEFINITION  Enterococcus faecium strain S2-6b plasmid pS2-6b-b, complete
            sequence.
ACCESSION   NZ_CP088193
VERSION     NZ_CP088193.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN23424489
            Assembly: GCF_023375205.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30822)
  AUTHORS   Biggel,M.
  TITLE     Characteristics of florfenicol resistant enterococci from fattening
            pigs
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 30822)
  AUTHORS   Biggel,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-NOV-2021) Institute for Food Safety and Hygiene,
            University of Zurich, Winterthurerstrasse 272, Zurich 8057,
            Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 99x,185x
            Sequencing Technology :: Illumina MiniSeq, Oxford Nanopore Minion
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_023375205.1-RS_2024_05_21
            Annotation Date                   :: 05/21/2024 04:26:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,678
            CDSs (total)                      :: 2,588
            Genes (coding)                    :: 2,490
            CDSs (with protein)               :: 2,490
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 98
            CDSs (without protein)            :: 98
            Pseudo Genes (ambiguous residues) :: 0 of 98
            Pseudo Genes (frameshifted)       :: 40 of 98
            Pseudo Genes (incomplete)         :: 56 of 98
            Pseudo Genes (internal stop)      :: 24 of 98
            Pseudo Genes (multiple problems)  :: 17 of 98
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP088193.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..30822
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="S2-6b"
                     /isolation_source="fecal sample"
                     /host="Sus scrofa domesticus"
                     /db_xref="taxon:1352"
                     /plasmid="pS2-6b-b"
                     /collection_date="2021"
                     /collected_by="ILS, University of Zurich"
     gene            complement(join(30271..30822,1..402))
                     /locus_tag="LQ050_RS13155"
                     /old_locus_tag="LQ050_13155"
     CDS             complement(join(30271..30822,1..402))
                     /locus_tag="LQ050_RS13155"
                     /old_locus_tag="LQ050_13155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_000429439.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLFE
                     KDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGSPG
                     SEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAADYII
                     AMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQKTID
                     KYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYYEQHGD
                     IEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
                     /name="ParA family protein"
     gene            1014..2507
                     /locus_tag="LQ050_RS13160"
                     /old_locus_tag="LQ050_13160"
     CDS             1014..2507
                     /locus_tag="LQ050_RS13160"
                     /old_locus_tag="LQ050_13160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="WP_000947691.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSKQ
                     LMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINTFV
                     VDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVIDVA
                     KKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSMKLES
                     DQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTLSLAYY
                     SSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELCQQWVSP
                     TLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLNLSKKELA
                     SQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLSKEKRLDYS
                     TRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
                     /name="primase C-terminal domain-containing protein"
     gene            2642..2938
                     /locus_tag="LQ050_RS13165"
                     /old_locus_tag="LQ050_13165"
     CDS             2642..2938
                     /locus_tag="LQ050_RS13165"
                     /old_locus_tag="LQ050_13165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication control protein PrgN"
                     /protein_id="WP_000053907.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTRE
                     KTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
                     /name="replication control protein PrgN"
     gene            3039..3890
                     /locus_tag="LQ050_RS13170"
                     /old_locus_tag="LQ050_13170"
     CDS             3039..3890
                     /locus_tag="LQ050_RS13170"
                     /old_locus_tag="LQ050_13170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002287227.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILDL
                     TVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAGKL
                     FKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILFFVG
                     YVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKGIRSI
                     LKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDLELPMK
                     DK"
                     /name="hypothetical protein"
     gene            3911..4123
                     /locus_tag="LQ050_RS13175"
                     /old_locus_tag="LQ050_13175"
     CDS             3911..4123
                     /locus_tag="LQ050_RS13175"
                     /old_locus_tag="LQ050_13175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002324171.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIEY
                     RTEYLELTNQTDFLLIRKQQEQEKN"
                     /name="hypothetical protein"
     gene            4556..5236
                     /locus_tag="LQ050_RS13180"
                     /old_locus_tag="LQ050_13180"
     CDS             4556..5236
                     /locus_tag="LQ050_RS13180"
                     /old_locus_tag="LQ050_13180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(<5282..5620)
                     /locus_tag="LQ050_RS13185"
                     /old_locus_tag="LQ050_13185"
                     /pseudo=""
     CDS             complement(<5282..5620)
                     /locus_tag="LQ050_RS13185"
                     /old_locus_tag="LQ050_13185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001611915.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(5865..7127)
                     /gene="mobV"
                     /locus_tag="LQ050_RS13190"
                     /old_locus_tag="LQ050_13190"
                     /pseudo=""
     CDS             complement(5865..7127)
                     /gene="mobV"
                     /locus_tag="LQ050_RS13190"
                     /old_locus_tag="LQ050_13190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            complement(7691..9067)
                     /gene="tet(L)"
                     /locus_tag="LQ050_RS13195"
                     /old_locus_tag="LQ050_13195"
     ARG             complement(7695..9067)
                     /name="tet(L)"
                     /gene="tet(L)"
                     /gene_name="tetracycline efflux MFS transporter Tet(L)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="98.69"
                     /coverage="100.0"
     gene            complement(9261..11180)
                     /gene="tet(M)"
                     /locus_tag="LQ050_RS13200"
                     /old_locus_tag="LQ050_13200"
     ARG             complement(9265..11180)
                     /name="tet(M)"
                     /gene="tet(M)"
                     /gene_name="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(11196..11312)
                     /locus_tag="LQ050_RS13205"
                     /old_locus_tag="LQ050_13205"
     CDS             complement(11196..11312)
                     /locus_tag="LQ050_RS13205"
                     /old_locus_tag="LQ050_13205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="WP_001791010.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
                     /name="tetracycline resistance determinant leader peptide"
     gene            complement(11557..12489)
                     /locus_tag="LQ050_RS13210"
                     /old_locus_tag="LQ050_13210"
     CDS             complement(11557..12489)
                     /locus_tag="LQ050_RS13210"
                     /old_locus_tag="LQ050_13210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="WP_001224319.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVLL
                     GLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSIDN
                     RMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQLITE
                     GENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSITTNEI
                     NEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTVSLTVE
                     YIDQQTKATQVSQFDLVLEKNGSNWKIVK"
                     /name="conjugal transfer protein"
     gene            complement(12486..>13199)
                     /locus_tag="LQ050_RS13215"
                     /old_locus_tag="LQ050_13215"
                     /pseudo=""
     CDS             complement(12486..>13199)
                     /locus_tag="LQ050_RS13215"
                     /old_locus_tag="LQ050_13215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /name="C40 family peptidase"
     gene            13231..13911
                     /locus_tag="LQ050_RS13220"
                     /old_locus_tag="LQ050_13220"
     CDS             13231..13911
                     /locus_tag="LQ050_RS13220"
                     /old_locus_tag="LQ050_13220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_013646119.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            14668..16296
                     /gene="poxtA"
                     /locus_tag="LQ050_RS13225"
                     /old_locus_tag="LQ050_13225"
     CDS             14668..16296
                     /gene="poxtA"
                     /locus_tag="LQ050_RS13225"
                     /old_locus_tag="LQ050_13225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002415638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein PoxtA"
                     /protein_id="WP_002415638.1"
                     /translation="MKGKNMNLAFGLEEIYEDAEFQIGDLDKVGIVGVNGAGKTTLFRL
                     LLGELELDNGSLTSGNARIGYLPQEIVLEDEDITVWDFLFEGRPIKKYEQELEEIYKKL
                     ETAVNAEQEALLARMGTLQERLEYFDFYEAETILLEFADKMSIDAELYHRPMRELSGGQ
                     KSKMAFARLLYSKPEILLLDEPTNHLDVSTKDFVIKYLKNYRGSVLIISHDIDFLNRII
                     NKIMYINKATHKISVYDGDYYIYKKKYAEEQRIREMAIVQQEKEIKELSDFVQKAKQAS
                     QTNHHLKRMGQERALRLDKKRGELQKRNRLYKRVKMDIRPKREGAQVPLEVENITFHYS
                     GYPTLYQNLSFQINGRERFLVVGENGVGKSTLLKLMMGILSPDEGCIRFNQKTDIAYYA
                     QELEQLDENKTVIDNVESEGYTPWQIRAVLSNFLFYDDDVNKKVSVLSPGEKARVALCK
                     ILLQKANLLILDEPTNHLDPETQKIIGGNFNLFEGTIIAVSHNPSFVEQIGISRMLILP
                     SGRIEPYSRELLEYYYEINGSVAKF"
                     /name="poxtA"
     gene            16350..17030
                     /locus_tag="LQ050_RS13230"
                     /old_locus_tag="LQ050_13230"
     CDS             16350..17030
                     /locus_tag="LQ050_RS13230"
                     /old_locus_tag="LQ050_13230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_013646119.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            17034..17564
                     /locus_tag="LQ050_RS13235"
                     /old_locus_tag="LQ050_13235"
     CDS             17034..17564
                     /locus_tag="LQ050_RS13235"
                     /old_locus_tag="LQ050_13235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002510381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_125276271.1"
                     /translation="MDTVRDFILYLKLCNRTVTRYILKQKTLGLFFLALTPVIDLILLI
                     TTGIDLMNGATAATPHAIAAVYISVSLVFGKSMINWADDRFGYYVMKQGPKPYKPVGLA
                     YSKNYAKSWLKHLLSYIIGTGILHLIIFLINDKSRTEAMDNVIHVWTIVIIIDLIICIS
                     YFVWPPKNTESKL"
                     /name="hypothetical protein"
     gene            17701..17958
                     /locus_tag="LQ050_RS13240"
                     /old_locus_tag="LQ050_13240"
     CDS             17701..17958
                     /locus_tag="LQ050_RS13240"
                     /old_locus_tag="LQ050_13240"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_013330744.1"
                     /translation="MTKYSESFKEMIVDLANNGTKAKDLSSEYGISEAAIYKWKKLYTK
                     DSKTGVNEKQMQTLRKEIKQLKLENEILRKAAAIFAQDPL"
                     /name="transposase"
     gene            <18312..18665
                     /locus_tag="LQ050_RS13245"
                     /old_locus_tag="LQ050_13245"
                     /pseudo=""
     CDS             <18312..18665
                     /locus_tag="LQ050_RS13245"
                     /old_locus_tag="LQ050_13245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019169163.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            19069..20478
                     /gene="fexB"
                     /locus_tag="LQ050_RS13250"
                     /old_locus_tag="LQ050_13250"
     ARG             19070..20475
                     /name="fexB"
                     /gene="fexB"
                     /gene_name="chloramphenicol/florfenicol efflux MFS
                     transporter FexB"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(20808..22142)
                     /locus_tag="LQ050_RS13255"
                     /old_locus_tag="LQ050_13255"
     CDS             complement(20808..22142)
                     /locus_tag="LQ050_RS13255"
                     /old_locus_tag="LQ050_13255"
                     /inference="COORDINATES: protein motif:HMM:NF037897.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_159373660.1"
                     /translation="MQQNQWEDILKWGTVIVPETSSYISDNPIQELDDMGFNSLPLNDN
                     HIIKENTTTEKRSKIDNLYHGSKEDFTEFKIPRFHKNGGTLGFGTYLTDSLQRAKSYAD
                     NDGYLYTIELNDELQNSTPLNASKVTLTTNQVAKIIEKIAQKQIDEEEYPYILSDWEEP
                     TSETAMDAGNKKIAYNIAEKIIDDTDDLSIINGINNQLGGNDSGAETLIPVLNEMGIHY
                     AELDVEYYDNSKEYVVFNPKDIKIVNQKLTKPEQSKKFVSDVDIKSLEEKAIKTIAKSE
                     LIVKANNPVEAMQKLYNNDLKSAIKASFILYDLPEDKIDSSKKNVTWEDLVNIEKSYNV
                     FSYYQNNLYGSELVEPDLNNPYQENTKILDNKATQKQPALSDQYKALHDKLKEPGANKQ
                     QIQEQLNKVKIEISQKTQQQLKDFAKANPDLKQPRVKKEQQALQR"
                     /name="hypothetical protein"
     gene            22204..22884
                     /locus_tag="LQ050_RS13260"
                     /old_locus_tag="LQ050_13260"
     CDS             22204..22884
                     /locus_tag="LQ050_RS13260"
                     /old_locus_tag="LQ050_13260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_013646119.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     ARG             23844..25468
                     /name="poxtA"
                     /gene="poxtA"
                     /gene_name="ABC-F type ribosomal protection protein PoxtA"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL/OXAZOLIDINONE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             14669..16293
                     /name="poxtA"
                     /gene="poxtA"
                     /gene_name="ABC-F type ribosomal protection protein PoxtA"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL/OXAZOLIDINONE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            25525..26205
                     /locus_tag="LQ050_RS13270"
                     /old_locus_tag="LQ050_13270"
     CDS             25525..26205
                     /locus_tag="LQ050_RS13270"
                     /old_locus_tag="LQ050_13270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_013646119.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            26403..27008
                     /locus_tag="LQ050_RS13275"
                     /old_locus_tag="LQ050_13275"
     CDS             26403..27008
                     /locus_tag="LQ050_RS13275"
                     /old_locus_tag="LQ050_13275"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="WP_000599739.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTFK
                     GLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEIIKK
                     YVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDLEIR
                     YLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
                     /name="protein adenylyltransferase Fic"
     gene            27024..27596
                     /locus_tag="LQ050_RS13280"
                     /old_locus_tag="LQ050_13280"
     CDS             27024..27596
                     /locus_tag="LQ050_RS13280"
                     /old_locus_tag="LQ050_13280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000170424.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRDR
                     PKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTSMG
                     RMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELLTSG
                     KSYKEVEAITGFSRSTLFRIKKKIEES"
                     /name="recombinase family protein"
     gene            complement(28029..28988)
                     /locus_tag="LQ050_RS13285"
                     /old_locus_tag="LQ050_13285"
     CDS             complement(28029..28988)
                     /locus_tag="LQ050_RS13285"
                     /old_locus_tag="LQ050_13285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS1252 family transposase"
                     /protein_id="WP_000222577.1"
                     /translation="MTYTHLTTDELVMIESYYHQNIKIVKIAEYLKRSRTPIYNVINFL
                     KEGHTALEYYQQYKENKKRCGRRNIVLPKKQQSYIKEKIAQGWTPDVIIGRKEKPISCS
                     VRTLYRQFKEKVFDESTLPMKGKRKPNGHQERRGKQAFKRNIVERETDYPTFKEEFGHI
                     EGDTIVGIHHKSAVITLVERLSKIIITLKPEGRKAIDIENTLNHWFGSIPRHLFKSITF
                     DCGKEFSNWKALSNQHDIAIYFADPGTPSQRALNENSNGLLRKDGLPKNMDFNQVDQAF
                     ISSVANKRNNIPRKSLDYQTPLEVFMSYMNEDILSSLI"
                     /name="IS30-like element IS1252 family transposase"
     gene            complement(29116..29796)
                     /locus_tag="LQ050_RS13290"
                     /old_locus_tag="LQ050_13290"
     CDS             complement(29116..29796)
                     /locus_tag="LQ050_RS13290"
                     /old_locus_tag="LQ050_13290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(30024..30299)
                     /gene="prgO"
                     /locus_tag="LQ050_RS13295"
                     /old_locus_tag="LQ050_13295"
     CDS             complement(30024..30299)
                     /gene="prgO"
                     /locus_tag="LQ050_RS13295"
                     /old_locus_tag="LQ050_13295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="WP_001196543.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVDP
                     PVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
                     /name="prgO"
     Typing          1015..2507
                     /name="rep_cluster_185"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(5869..7127)
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="95.952"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tctcaattct tctaaaggtt taatgaaggc caatgatctc ttacgacgat caggatattt
       61 ttcggacaag tattcattaa gttcttcaga tccaggagag ccagccataa tatataaatg
      121 tggacttact tgagtaatac ctgaaaccca gtcccctttt ttgattgctg cagacatgga
      181 tcgatcaaag ctagtaattt gatacgttga tccaatgttg gaagtagtat ttctttgttg
      241 gtcataatca attagcaaca cgtctttttc aaaaagttga ctagaaacaa tcgctaataa
      301 atcattgtct gtagtcttac caatgccgcc ttttctacct gtaagcatta caacttttcc
      361 tagtttatct gatgttttaa atgcagtccg taagttttcc atagttccct ccaatttcct
      421 atactaaata tatttagtat acttcatata cttaatatat tcgatatatc taatatactc
      481 caaattgata agaattcaga ctttataagg aatatagtgg atatactaaa tatatttgct
      541 atattcagta tatcagatat attcaaaatg tcaaaatata tttgtgcgtt ttgcgttgac
      601 aatttagagt gaaaagaggt aaacttaatt ctatagaaac cacagataat tcactattta
      661 caaagtagca aaagcagtgg tactctttaa acagaaaaat tacataaaaa aaagagacgg
      721 aaataattga ttttagcaga atcaattatt tctgaatcac atggttagga catgtgttca
      781 cgctcgtctc aagaatatgt aagtagctac caactactta tattaaaagt tgatcggata
      841 ccttttccga ttgcctttat tctaccaaaa aaaggcgagc aactcaacag aagaaagttt
      901 atttagtgta cttaaattaa atattcttaa acactgaaga gagaacacat actatggctg
      961 agattaaagc taaactgtgt tctctttttg tttgagaaag gacgttacaa tcgatgttga
     1021 gcgaaattta ttcagctatt cttaaaaacg gcttacgtac atacaaatat cgaaacagca
     1081 ccatgaaacc tgcaggtcat attgattcca gtaggagtgg tgctatcttt gcgtaccgta
     1141 gcaagcaatt aatgaatgtt gggcgtggta tggtcattac ttcggaagaa gctattttag
     1201 agaacgaaaa gaaactaacg cattggacac ctaataccta tcgctttggt acttatgcgg
     1261 atgattatcg aacagtggtt aaaggtcatt ctgagaaaaa cttaagtcaa atcaacacat
     1321 ttgtagttga tatcgattca aaagagaacc atcaaggcga aattatttta gcctgtttag
     1381 atcaagtggg ctacatgcca acgctaattt tagaatcaga tcatggttat caagtttatt
     1441 ttgtactaaa gacaccaggc tatgtcacaa agaaaagcaa tttcaaggtg atcgatgtag
     1501 caaaaaaaat ttcaaaaaca attcgtctac agttggctga aaaattgtcc ggagtggatc
     1561 taggatgtaa ccacttcgga attgctcgat tcccacaaga aaataatatt gtttttaaag
     1621 aaatgaacta tcagtattct tttgctgact ggattcaatg gtcgatgaag cttgaatcag
     1681 atcaaaaaac aaaagaagat cgagaacgaa aactaattgt ctttcctgag aaaaaagaaa
     1741 ttcgtcaagt agatgaaccg tggttcgata tgttacttca taaagcaaac atcgtcggcg
     1801 gagaaggacg tcttggtcga aataatgtga ttttcacgct ttctttagct tattactctt
     1861 caggttatgc attggatact tgcgaataca atatgttcac attcaacgaa cggttacagg
     1921 aaccgctatc tgaagcagaa ttagtaaaga ttgtacgtag tgcttattct ggtaattatc
     1981 aagcagcaag cagagaattc attattgaat tgtgccagca atgggtttca ccaaccttaa
     2041 aaaataatga tctgttcatt caacgacgtg gctggtggaa atttaaaaag ccacgagatc
     2101 aaagaaaata tagtcataaa aatgaatgga aagaagatct attggcttat ctaagcgaaa
     2161 aaagtcttgc tagtgagcct tatttgaacc tgtcaaaaaa agaattggct tcacaactaa
     2221 cgatgcccaa gcgaacactt gataagatct taaatgagtt acgagaggag aataaagtct
     2281 tctacaaggt aacacgagga agaaatggcg gaatgatcat tgcttcagtc aaaacgttgt
     2341 tcgcgagggt tattcaacta agtaaagaaa agagactaga ttattcaaca aggatcacag
     2401 aggtatttgg actcaacgag agcttagtag aagagacatt tagacaatta tcaaccccct
     2461 tgaaccctct taaagaagtg aatctttttg aagtagatac aggttgaaaa ataaaaggtg
     2521 caaattgccc tatacaatat atctatgata cttctgtagg tgttgctccc tttgcctagc
     2581 tacgtgtagg tggtatactt ataactgcgt atgcagtctt atgtatcatg gaggaagttg
     2641 tatgtcgtta aaaaattatg tctattcaca tcctgttaat gtgtttatca ttggtcgttt
     2701 gggattatct gtggaagtgt tctgtgagct ttatggtttt aagcagggga ctttgtcttc
     2761 ttgggttacc agggaaaaaa cagttgcttc tttgccgatt gagtttcttc atgggttgtc
     2821 cttagcttct ggggagacta tggatcaggt atatgattgt ttgtgtgtgt tagagcagga
     2881 gtatattgag tataaaatag ctaacgagtt aagaaaaagg aagaagtata tccagtagta
     2941 gtttttattt acttaaaaaa ttggttcatt gagcaaccta tcgctgctaa agtagcaaag
     3001 gaaaacgtta aaggaaagaa tttagggaag aaatcgaaat gaaatcggac gactggattg
     3061 aacacacctg gcttcctctg aaaagaaata gcaaacgaaa gaaattttgg gtattgcaat
     3121 tatggccatt aggaaaactt tgtagttacg gggcacgact tattcttgat ttaaccgttt
     3181 actcgattgg agtatttgga acggcttatt acttgataaa tgatcccaat aggattgcag
     3241 catcagacat ttttacagtg ctaatgacgt tgatttttgt catgctattg tctattttta
     3301 ctcaattagt catgcaattt accaggcaaa aattaacagc aggaaaactt ttcaaaagcc
     3361 tattcgattt aattgttgta aatgcaattc tagcgacttt aataaaacaa attgaacaat
     3421 ctggaagaac aacaaaagga gtgaaggatt ttttattgac gtttattcac tttgtaaatg
     3481 gacacatgta tttgtttgaa gtgggtatta ttctcttttt tgtcgggtat gtatccacga
     3541 aacttattaa acgttcaatt gaaaaagaaa ttgaaattga cctgattccg acacttcttg
     3601 gttatgagta caatgttgat tttggaagat atgacgaatt gatcaatacg gatatcgttc
     3661 acacgagtat ccatgaatct actgttaagg gcatcagatc tattttaaaa aatggccagg
     3721 aaatgaaagc aatagatcga agaaaagaga tctacaattt ttatgaagtc gaagcaagcc
     3781 tacgatatgg catcggaaaa ttgtggttag atggaagtaa tattcgtcaa aacaaaccat
     3841 acattttttg gaacagtagt gatttagaac ttccaatgaa agataaataa ttatggagaa
     3901 tcgtttgaaa atgattcctc tatacaggat tgtgcttata gttggcatgg agttaaaaac
     3961 cttaaagaag gagcagttat tcaaagtgaa agaacgtcat aatcagttac tatgtagtaa
     4021 aacgggtacg atgaacattg aataccgaac agaatattta gaattaacga atcaaactga
     4081 ttttttgttg attcgaaagc aacaagagca agaaaaaaat taatggctac ttatagccaa
     4141 ttgattgatg aatgggaaca attcaaggaa tctaaaattc cagaacgtct ctaaaagcct
     4201 ttatttgtaa agagcataag gaaacgtggg aacacttttt aaaaaaagtg ttccaatagg
     4261 ctgtgcctat tacgtttctc aaaaataaat gtgggaacaa aatatttaaa aataggatag
     4321 tgaaaggata gtgaaggata gtaaaaggag ggtagtagga tagcaaaaag gataggctcc
     4381 ttttcgctat cctttttaaa ttggaggaat taatatggaa gtaagaataa gaaatgtgga
     4441 tgagaaaatc gtaagagaaa ttgatcgaag atgtgacgaa cggttctgtt gcaaagtttt
     4501 aaatctacta tcaaataagg tagaataata gaaaaagata gcaggaggaa tgacgatgaa
     4561 tcattttaaa ggaaagcaat ttcagcagga tgtgattatt gtagccgtgg gctactatct
     4621 tcgttataac cttagctatc gtgaagttca agaaatctta tatgatcgtg gcattaacgt
     4681 ttctcatacg acgatttatc gttgggtgca agaatatggc aaactactct atcaaatttg
     4741 gaaaaagaaa aataaaaaat ccttttattc atggaaaatg gatgaaacgt acatcaaaat
     4801 taaaggaaaa tggcattatt tgtatcgagc catcgatgca gatggtttaa ccttggatat
     4861 ttggttacgt aaaaaacggg acacacaagc agcctatgct tttcttaagc ggttagtgaa
     4921 gcagtttgat gaaccgaagg ttgtagtcac agataaagcc ccctctatta caagtgcctt
     4981 taagaaacta aaagaatacg gcttttatca agggacagaa catcgtacca ttaaatacct
     5041 gaataatttg attgaacaag accatcgtcc agtaaagaga cgcaataaat tctatcgaag
     5101 tttacgcact gcctctacca cgattaaagg catggaagcc attcgaggat tatataagaa
     5161 aacccgaaaa gaaggcactc tcttcgggtt ttcggtctgt actgaaatca aggtattatt
     5221 gggaatccca gcttaaatca tagataccgt aagggatttt attctttatt taaaactttg
     5281 caacagaacc cttttgttta ataacttcag caacaacctt ttgtgactga atgccatgtt
     5341 tcattgctct cctccagttg cacattggac aaagcctgga tttacaaaac cacactcgat
     5401 acaactttct ttcgcctgtt tcacgatttt gtttatactc taatatttca gcacaatctt
     5461 ttactctttc agccttttta aattcaagaa tatgcagaag ttcaaagtaa tcaacattag
     5521 cgattttctt ttctctccat ggtctcactt ttccactttt tgtcttgtcc actaaaaccc
     5581 ttgatttttc atctgaataa atgctactat taggacacat aatattaaaa gaaaccccca
     5641 tctatttagt tatttgtttg gtcacttata actttaacag atggggtttt tctgtgcaac
     5701 caattttaag ggttttcaat actttaaaac acatacatac caacacttca acgcaccttt
     5761 cagcaactaa aataaaaatg acgttatttc tatatgtatc aagataagaa agaacaagtt
     5821 caaaaccatc aaaaaaagac accttttcag gtgctttttt tattttataa actcattccc
     5881 tgatctcgac ttcgttcttt ttttacctct cggttatgag ttagttcaaa ttcgttcttt
     5941 ttaggttcta aatcgtgttt ttcttggaat tgtgctgttt tatcctttac cttgtctaca
     6001 aaccccttaa aaacgttttt aaaggctttt aagccgtctg tacgttcctt aaggaattcc
     6061 ttagtgcttt catagattaa actcacatca cgctttaaat cgcttatttt agactttaaa
     6121 gacttgtttt cttcaagcaa ctcattataa tcatttacat tttcattaaa tcgctctaca
     6181 agaccactat atttttcttt aacttgccca tgttctttac ttaatttttt atattctctc
     6241 gccatatcag tactcatgag atttctaaca tgctgtttta acctatcgtt atctctcgca
     6301 gcagtcacta agtttttata atcacgctcc gatataacaa catttttggt tggtttcttt
     6361 tctgttttca ttatttcttt tcccaaacca aacatggact tttcacccgt tggcacttca
     6421 acacttttca tgtgtcgttt cgctggtact tctaaatctg atttaacttt atcgctataa
     6481 gcagtccatt catctttttt aactgctaaa tttttttcta gaaaatcaat ctctttttcc
     6541 aaagtttgtt ttttaaattt agctgtctca atatgtttac ggtcagagcc acgttcacca
     6601 cgcttcaact caaaaccctg ttttttcata tgctcgggga atttatcttg tagccataac
     6661 agttcttgac gattaaacac attttttcct tgcagttttc catcacgcat aggcacaaca
     6721 cctaaatgca tgtgaggggt ttgctcatca ttatgaactg ttgcataagc aatattttgc
     6781 ttgccatatc gttcggaaaa taatttataa ctttcctcaa aaaatcgttt ttattctcct
     6841 ggatccagtt gctcaaaaaa atctcggtca gatgttacta gcaactcatt tacaagaaca
     6901 gcatctttcc tcgtttttct tgtacctgtt ttttgtgatt caataatttc tttgacacgt
     6961 tcgttgtaat caatattttt atcatttttc aaatcataat tttcacgtgt tcgctcatgg
     7021 tcaatatcat cattcgttct actttttcgc tctctttgat tatgaaattg catgcctttt
     7081 agtccagctg atttcacttt ttgcattcta caaactgcat aactcatatg taaatcgctc
     7141 ctttttaggt ggcacaaatg tgaggcattt tcgctctttc cggcaaccac ttccaagtaa
     7201 agtataacac actatacttt atattcataa agtgtgtgct ctgcgaggct gtcggcagtg
     7261 ccgaccaaaa ccataaaacc tttaagacct ttcttttttt tacgagaaaa aagaaacaaa
     7321 aaaacctgcc ctctgccacc tcagcaaagg ggggttttgc tctcgtgctc gtttaaaaat
     7381 cagcaaggga caggtagtat tttttgagaa gatcactcaa aaaatctcca cctttaaacc
     7441 cttgccaatt tttattttgt ccgttttgtc tagcttaccg aaagccagac tcagcaagaa
     7501 taaaattttt attgtctttc ggttttctag tgtaacggac aaaaccactc aaaataaaaa
     7561 agatacaaga gaggtctctc gtatctttta ttcagcaatc gcgcccttta atggaacaaa
     7621 aagatttgaa ttcctgttat aaaaaaagga tcaattttga actctctccc aaagttgatc
     7681 ccttaacgat ttagaaatcc ctttgagaat gtttatatac attcaaggta accagccaac
     7741 taatgacaat gattcctgaa aaaagtaata acaaattact atacagataa gttgactgat
     7801 caacttccat aggtaacaac ctttgatcaa gtaagggtat ggataataaa ccacctacaa
     7861 ttgcaatacc tgttccctct gataaaaagc tggtaaagtt aagcaaactc attccagcac
     7921 cagcttcctg ctgtttcaag ctacttgaaa caattgttga tataactgtt ttggtgaacg
     7981 aaagcccacc taaaacaaat acgattataa ttgtcatgaa ccatgatgtt gtttctaaaa
     8041 gaaaggaagc agttaaaaag ctaacagaaa gaaatgtaac tccgatgttt aacacgtata
     8101 aaggacctct tctatcaaca agtatcccac caatgtagcc gaaaataatg acactcattg
     8161 ttccagggaa aataattaca cttccgattt cggcagtact tagctggtaa acatctttca
     8221 tcatataagg aaccatagag acaaaccctg ctactgttcc aaatataatt cccccacaaa
     8281 gaactccaat cataaaaggt atatttttcc ctaatccggg atcaacaaaa ggatctgtta
     8341 ctttcctgat atgttttaca aatatcagga atgacagcac gctaacgata agaaaagaaa
     8401 tgctatatga tgttgtaaac aacataaaaa atacaatgcc tacagacatt agtataattc
     8461 ctttgatatc aaaatgacct tttatcctta cttctttctt taataatttc ataagaaacg
     8521 gaacagtgat aattgttatc ataggaatga gtagaagata gtaccaatga atataatggg
     8581 ctatcattcc accaatcgct ggaccgactc cttctcccat ggctactatc gatccaataa
     8641 gaccaaatgc tttaccccta ttttcctttg gaatatagcg cgcaactata accattacga
     8701 gtgctggaaa tgcagctgca ccagcccctt gaataaaacg agccataata agtaaggaaa
     8761 agaaagaatg gccaacaaac ccaattaacg acccgaaaca atttattata attccaaata
     8821 ggagtaacct tttgatgcct aattgatcag atagctttcc atatacagct gttccaatgg
     8881 aaaaggttaa cataaaggct gtgttcaccc agtttgtact cgcaggtgtt ttattaaaat
     8941 aatttgcaat atcaggtaat gagacgttca aaaccatttc atttaatacg ctaaaaaaag
     9001 ataaaatgca aagccaaatt aaaatttggt tgtgtcgtaa attcgattgt gaaaaggatg
     9061 tattcacatt tcaacctcca ataatgaggg cagacgtagt ttatagggtt aatgatacgc
     9121 ttccctcttt taattgaacc ctgttacatt aattacactt cataattaat tcctccttta
     9181 cactttaatt caaatcttta ttaaaaaata tttcatctta tttaacaaga aaccatattt
     9241 atataacaac ataaaataca ctaagttatt ttattgaaca tatatcgtac tttatctatc
     9301 cgactatttg gacgacgggg ctggcaaaca ggttcaccgg tagtaacatg gtaccctttt
     9361 aactctgtta aacaaacact acgtccattt gtaaagaaag ttaaatcact acgatattct
     9421 tgaatacacc gagcagggat ttctccacta agaatgacct cattattttt caattgagtg
     9481 tctacgatgt tcgcacaata tttaggagca tcgttgtatg ctcgtgaaag atattcctgt
     9541 ggcgcataaa ttttaaaact aagatatggc tctaacaatt ctgttccagc tttttttaag
     9601 acttgttcca atacaatagg agcaagcatc cgaaaatctg ctggggtact aacagggcta
     9661 tagtataagc catacttaaa acagatttta caatccgtca cattccaacc atataatcct
     9721 tgttcgcaac catagcgtat cccttccata actgcatttt gaaatgattg atttaagtat
     9781 ccaagagaaa ccgagctctc atactgcatt ccacttccca acggaagcgg tgatacagat
     9841 aaaccaatgg aagcccagaa aggatttggc ggcacttcga tgtgaatggt atattctgca
     9901 ttttttaacg gtctctccat ataaatgact gtaggctctt ttagttctat ctccacatga
     9961 tacttttctt gcaacagtgc actaatcact tccatttgta ctttccctaa gaaagaaagt
    10021 ataatttcat gtgtcgtaga atccacataa tattgtagaa gcgggtcact gtcggagatt
    10081 tctaaaagtg catcaagtaa catttccctt tgttgaggtt tgctcggttc aacagttgtt
    10141 tgcagcagag ggagcggatt ttcaattctc tctctctgtg gcaatagctt tgtatctcca
    10201 agaacactat ttagcttcaa aaactcattt tgcaaaataa caatttcccc ggaataagcc
    10261 ttatcaattt tacataattc accatttatt gaagtataca tttctgtaat ttttattttt
    10321 tccttttccg atattctaac cgaatcccgc aaatgcagga ttccgccata aaggcgtaca
    10381 tatgcaagac gttgtctttc ttccgaatat tcaattttga agacatttcc gcaaagttca
    10441 gacttctttc tgtatgttga tgaataaaat ttattcgtta tcacttctat aagctgctca
    10501 atccctatgt tgctttttgc gcttccatga taaacagggt acaaggagca attctgaaat
    10561 cttctgattt cctcttgttc gagttctaat gcttctaatg atttaccgga catatatttc
    10621 tctaaaaggt catcatttcc ttctattacc acatcccatt gctcaggttc cgtacagctc
    10681 atcacacaca tattagggtg cagctctact ttctgtttga ttataatttc catagaaagt
    10741 ttctctttaa tatcctgata aaccgttgat aaatcaattc cattttggtc aatcttattg
    10801 ataaaaaaga ttgtgggaat ccccattttc ctaagtgcat gaaataatat acgagtttgt
    10861 gcttgtacgc catcttttgc agaaatcagt agaattgccc catctaaaac tgataatgaa
    10921 cgatatactt ctgctaagaa atccatatgt cctggcgtgt ctatgatgtt caccttcgta
    10981 ttttcccact gaaaagaggt tattcctgtc tgaattgtaa ttcctctctg acgttctaaa
    11041 agcgtattat ccgtcctcgt tgtacctttg tccacgcttc ctaattctgt aatcgctcca
    11101 ctgttatata ataagctttc tgttaaggta gtttttcctg catcaacatg agctaaaact
    11161 ccaatattaa taattttcat gtgattttcc tccattcaaa aacccaaaag ggcataaaaa
    11221 tcccagtgat aaatactttt atcactggga tttttatgca taaccatagg tatacaaagc
    11281 atacagatat tctctggata ctttagaatc acatgataaa ggtattctta aactgggtac
    11341 aaaaaactaa gccctcctaa aaaaggacat ctaattattt gttcctgcta tcaaattgac
    11401 agtttattta agaatacctt gccgcatatt tattaactcc ttttaaatag tcacttaaat
    11461 aatagcacgt aagagcatat ttgtaaagga atctccaatt ttttatcaaa aagagtacat
    11521 gattacaaag tatctgtaat catgtaccaa tatttgttat tttacaatct tccaattact
    11581 cccgttcttt tcaagtacca aatcaaattg agatacctgc gttgctttgg tctgctggtc
    11641 gatatactcc actgtcagcg ataccgtgac ttgattatcc ttacgattgt gaataggatt
    11701 taccagttct tgaaagatgt actcttttcc gattggtttt aatatcccgt cattcacata
    11761 gtaggaaagt tcactggctg tcgctgtagg atagagcttg aagaacgtcg ttaaaaactc
    11821 attgatttca ttggttgtaa tggaatcaac cgtcccctca ctttcaatgg cttttggttt
    11881 ataacttgat ttcttaggta tgttggtaat ggtcggattc ttaaccagta ccatatttcc
    11941 agaaccatct acatagacac tcactatata agcagagtgg acggtctttg tattttctcc
    12001 ctctgtaatg agctggtcta cactgtaggt tacattaaac tcattgtcgc cagttggctc
    12061 taccgtccat atctgaaatc ctcttacaga agacgataca ggaatatctt tgcgtactgt
    12121 atcaacattg agagcttgaa gttcatctgt cagatagcct tttagacttt ccattcgatt
    12181 atcaatggac ttatcggatt gctcccatga atagtagact ttcgcaaagt tctctacaaa
    12241 attttctaca tgatgagtat caacgtattc cttttctatg atagttgttt cgtgaatagt
    12301 atgagtatct atagctgtaa agtgcttgaa tatcgcaaag ctgaaactaa gccctaaaag
    12361 tacccacaag gcaatcacaa cctttttatg aggattgacc ttatagacac gaggtttctt
    12421 ttcctttggt atctgttttt ctttattctg attttttcta aatttcatca ttaaatcttc
    12481 ctttctcatt gtttgattcg tcctgctccc actaaatgct gttgccagta ggggcttgtt
    12541 aagtcggcat aaccgattgg gtcgcctgca tgaaacatac ggttattgcc aaggtatatc
    12601 ccaacatgag taatataaga gccagcgtta taggtagaat gaaagaaaac caaatcgcca
    12661 gcttgtgctt ccgatagtgg gatatgctgg gtcacatcat attgctgttg tgcggttcgt
    12721 ggtaagttaa ttccagcttt tccatacgtc cattgtgtca gtccgctaca atcaaaagaa
    12781 gtagtcgggg aagctccacc gtaaacgtat cgccagccct catatttcag tgcttcgtcc
    12841 atgatggctt gtaccgtatc atcatcaaac tctgttgtga caagatactg cgttaccagt
    12901 tgcacataaa acatattgcc atagttgtat cgccagcccc cattgatagg tatggctatg
    12961 ggattggggt aagacacttt ttcgccacct gaatactctt ttgagaaact ttgagccagt
    13021 tcaaaggtat atttatttcc acgattagcc acatacccta agaaaccacc accataattg
    13081 taggactgga taaccgattc taaatctaca ctgagccttt cgctactggc taataattca
    13141 ctgaaatact tcacacggtt ctgttgcaaa gttttaaatc tactatcaaa taaggtagaa
    13201 taatagaaaa agatagcagg aggaatgacg atgaatcatt ttaaaggaaa gcaatttcag
    13261 caggatgtga ttattgtagc cgtgggctac tatcttcgtt ataaccttag ctatcgtgaa
    13321 gttcaagaaa tcttatatga tcgtggcatt aacgtttctc atacgacgat ttatcgttgg
    13381 gtgcaagaat atggcaaact actctatcaa atttggaaaa agaaaaataa aaaatccttt
    13441 tattcatgga aaatggatga aacgtacatc aaaattaaag gaaaatggca ttatttgtat
    13501 cgagccatcg atgcagatgg tttaaccttg gatatttggt tacgtaaaaa acgggacaca
    13561 caagcagcct atgcttttct taagcggtta gtgaagcagt ttgatgaacc gaaggttgta
    13621 gtcacagata aagccccctc tattacaagt gcctttaaga aactaaaaga atacggcttt
    13681 tatcaaggga cagaacatcg taccattaaa tacctgaata atttgattga acaagaccat
    13741 cgtccagtaa agagacgcaa taaattctat cgaagtttac gcactgcctc acccacgatt
    13801 aaaggcatgg aagccatccg aggattatat aagaaaaccc gaaaagaagg cactctcttc
    13861 gggttttcgg tctgtactga aatcaaggta ttattgggaa tcccagctta aatcatagat
    13921 accgtaaggg attttattct ttatttaaaa ctttgcaaca gaaccaaaat gagcatttct
    13981 tactatccta ttaaacgagt atagctatcc tatcggcagt agcgttgtct atggttatgg
    14041 cttgcctgca tattaaaaaa gggcaaaaga aaaacagagg attttacccc tctgtttcct
    14101 cttttgcgtt acatattcag tttacagttg tacaatactt ggtctataaa caaactgtaa
    14161 agtgagcagc ttagatgagc tattgacata tgcactcaag ctctctataa ttaaaatata
    14221 aaataagaga gggtgagcac agtgttattc gggaagtttt gcattgattt tggctctaca
    14281 caacaatata agacagagca ttgtgtggag cccaatcaga taaaatgttt atttgagagg
    14341 cagggctatt taaatcagaa atttgtgatt taagagcctt atttgtgttg cctttcaata
    14401 agcaaactca atgattggat atgtggccgt agacaatgtt ttgtctacgg ccttttgctg
    14461 tctatatttc atctatgtta ttggcatagt gtctgaaaaa gcagagggct acgtctatgg
    14521 gacgtattgc tacctctgct tttatttttt aaatgatgat atcagagaag aaaatatatc
    14581 cccgcacagg agataatcaa gcaaggaaaa ctgtaagcca taaaatgatg gcttgcagta
    14641 tgtatgacga tggaggaatg atacaagatg aaaggtaaaa atatgaattt agcctttggg
    14701 ttggaagaaa tttatgagga tgctgagttt caaatcggag atttggataa ggtcggtatt
    14761 gtcggcgtga acggagccgg aaagaccacc ttgttccgcc tgctgttggg agaacttgaa
    14821 cttgataatg gttcactgac cagtggaaat gcccgtattg gttatctccc acaggaaatt
    14881 gtcttggaag atgaggatat taccgtttgg gatttccttt ttgagggacg tccgattaaa
    14941 aagtatgagc aggaattgga agaaatctat aaaaagcttg aaaccgcagt caatgcagag
    15001 caggaagcac tgcttgcccg aatgggaaca ttgcaagaac gcttggagta tttcgacttc
    15061 tatgaggcag aaacaattct gttggagttt gcagataaaa tgagcattga tgcagaatta
    15121 tatcatcgtc cgatgagaga gctttcaggc ggacaaaaat ccaaaatggc atttgccaga
    15181 ctactatatt caaaaccgga aattctattg ttggatgagc ctaccaacca tttagatgtc
    15241 agcacaaagg attttgttat aaaatactta aagaattata ggggttcggt actgattatc
    15301 agccatgata ttgattttct aaatcggatt atcaacaaaa ttatgtacat caacaaagct
    15361 acccataaaa tatctgttta tgatggagac tactacatct acaagaaaaa gtatgcagag
    15421 gaacagcgga ttcgtgaaat ggcgattgta cagcaggaaa aagaaataaa ggagctttcc
    15481 gattttgtac aaaaagcaaa acaagccagt cagaccaatc atcacctcaa acgaatgggt
    15541 caagagcgag ccttgcggct tgataaaaag cgtggagagc tgcaaaagag aaatcgactg
    15601 tacaagcgtg tgaagatgga tattcgcccc aagcgtgaag gggcacaagt tcccttagag
    15661 gtggaaaata tcaccttcca ctattcgggg tatcccaccc tttatcagaa cctttccttt
    15721 cagattaacg gaagagaacg atttcttgtg gtgggtgaaa acggtgtcgg taaatccacc
    15781 ttattgaaat tgatgatggg tattctcagt ccagatgaag gatgcattcg ctttaaccag
    15841 aaaactgata ttgcatatta tgcacaggaa ctcgaacagc ttgatgaaaa caaaacggtc
    15901 attgacaatg tggagtctga aggatataca ccgtggcaaa tcagagccgt actgagcaac
    15961 ttcctgtttt atgatgacga tgtaaacaag aaagtatctg tgctgtcccc tggagaaaaa
    16021 gcaagggttg ccctttgcaa aatcctatta cagaaagcca atcttttgat actggacgag
    16081 ccgaccaacc accttgaccc agaaacgcag aaaatcattg gcggcaactt caatttgttt
    16141 gagggaacca ttattgccgt tagccataac ccatcctttg tggaacaaat cggaattagc
    16201 cgtatgctta ttttgcccag cggtcgaatt gaaccctatt cccgtgagct gcttgagtat
    16261 tattatgaaa tcaacggttc tgttgcaaag ttttaaatct actatcaaat aaggtagaat
    16321 aatagaaaaa gatagcagga ggaatgacga tgaatcattt taaaggaaag caatttcagc
    16381 aggatgtgat tattgtagcc gtgggctact atcttcgtta taaccttagc tatcgtgaag
    16441 ttcaagaaat cttatatgat cgtggcatta acgtttctca tacgacgatt tatcgttggg
    16501 tgcaagaata tggcaaacta ctctatcaaa tttggaaaaa gaaaaataaa aaatcctttt
    16561 attcatggaa aatggatgaa acgtacatca aaattaaagg aaaatggcat tatttgtatc
    16621 gagccatcga tgcagatggt ttaaccttgg atatttggtt acgtaaaaaa cgggacacac
    16681 aagcagccta tgcttttctt aagcggttag tgaagcagtt tgatgaaccg aaggttgtag
    16741 tcacagataa agccccctct attacaagtg cctttaagaa actaaaagaa tacggctttt
    16801 atcaagggac agaacatcgt accattaaat acctgaataa tttgattgaa caagaccatc
    16861 gtccagtaaa gagacgcaat aaattctatc gaagtttacg cactgcctca cccacgatta
    16921 aaggcatgga agccatccga ggattatata agaaaacccg aaaagaaggc actctcttcg
    16981 ggttttcggt ctgtactgaa atcaaggtat tattgggaat cccagcttaa attatagata
    17041 ccgtaaggga ttttattctt tatttaaaac tttgcaacag aaccgtaaca agatatatct
    17101 taaaacaaaa aacactaggt ctatttttcc tagcacttac accagttata gatttaatat
    17161 tacttataac aacaggtata gacctcatga atggagcaac agctgcaacc cctcatgcta
    17221 tagctgcggt ctatatttca gtatctcttg tctttgggaa aagcatgata aattgggcag
    17281 atgatagatt tggatattat gtgatgaaac aaggacccaa accttacaaa cctgtaggat
    17341 tagcttactc taaaaactat gctaaaagtt ggttgaaaca tttactttct tacattatag
    17401 gaacaggtat tttgcatttg attatttttt taattaatga taaaagtcgt acagaagcta
    17461 tggataatgt tattcatgtt tggacaattg tcattattat tgacttaatc atttgtattt
    17521 catattttgt gtggccacca aaaaatacgg aaagtaaatt atgattacaa ttttaaaaaa
    17581 agaaaatact gacgttttga actgacctca attagtggga gttggtgcta gtatgaaaat
    17641 taggacgcct tttcgtagag tcttgaatca aatataatga gactaaggaa ggtgtctaaa
    17701 atgacaaagt acagtgaatc ttttaaagaa atgattgttg atttagctaa taatgggaca
    17761 aaagcgaagg atttaagtag cgagtatggc atttcagaag cagccattta taaatggaaa
    17821 aaattataca cgaaagactc taaaaccggt gttaatgaaa aacaaatgca aacccttaga
    17881 aaagaaataa aacaacttaa actcgaaaat gaaatactaa gaaaggcagc cgccatattc
    17941 gctcaagatc cactttaact aaagtccgtt ggattaaacg ctattcaaaa atctttaatg
    18001 ccagccatct atgccgcata ttaaatgttc caagaagctt atattattac tgtattaaag
    18061 agaaatattc tgttagaaat gagagactcc ttcgttttaa agttttaatc aaagccttat
    18121 accatcaata taatggcatc tatggtgcgc ctaaaatcca cgcttttttg acacaaaaag
    18181 gctataatgt ttctgttaag tatgttcaaa aaatcatgcg gttacttggc attacttctg
    18241 ttaccattaa aaaattcaaa cactatacta attccaaagt taaaggtgtc tttaaaaata
    18301 tgctgaaaag tatgatgcta tctatcttaa agaatgcaac catcctaatg aaatttggca
    18361 agcagatcat actatgttag atatagaggt tttaaacgaa aaaaacaaac ttgaaagacc
    18421 ttggctaact gttgtcttag atgatttcag aacaagaaag aaatgagagt aaacgtcggc
    18481 aaacgcaagg gattaaagta gcgaaagaaa aaggagtata caaaggacga cctgtacttt
    18541 attcaccaaa tgcaaaagat tctcaaaaac gtttagttta ttactgagtt atagaaatgt
    18601 tagacaaatg tttttcaatt agcaatatag ttacggaagt agatgttact agacaaacta
    18661 tatagagtat taaaaataat caaataaact cataatttta aaatttacta ctctattttg
    18721 ctcaaaatag agataaaact gacaaattta ctcttttgtg ttattttggt atagattaat
    18781 ataagaggag gataaaaatg atggaaatgg tgtttaccct ttataaaaca attaaagttt
    18841 cagactatct caaagttgag ggacaagtat gtactttttt aaacagaata ccaaaatcca
    18901 gactttttac tataatcctt acgtaaaaaa gtaaaatatt gatttatgta acaaaagtct
    18961 gatcttaaga ttaggttttt tatttggata attgagaggt gaaattgatg gttaaagcag
    19021 tcgatttagc cttctaaaat gagcatttaa attttaggag gctgtaaaat gaatcatcaa
    19081 aatgaaaaaa atatagcatc aaatgtgttg ttaattagta tcttaggctt gtctgtttta
    19141 gtgggttcag ttactgcaga tatggttaat cctgttctcg gtgtgattgg aaaagaatta
    19201 ggtgggtctg aggcgcaagt tagttgggtc gtaagtggtg ttgccttagt tctatctata
    19261 gcaattccct tttatggacg tttatctgat tttttaaata ttaaaaaact ctttactaac
    19321 ggatttctaa tattaactat aggaagttta atatgtatat tcgcgcccaa tttaattatt
    19381 ttagtattgg gtagaatgtt tcaaggagct ggcatggcag ccatacctgt gctatctatt
    19441 gttataatat ctaaaattta tccgcctgga cagagaggaa gaattttagg tattattgct
    19501 ggttgtattg gcgttggcac tgcaggaggc ccaatatttg gcggcgttgt aggacaatta
    19561 ttaggttggc aatcattatt ttgggtcact tttgttctgg gtttaattat agttctaggt
    19621 gttcaaatat caatgcctaa aatagaatca ccagataata acagtcatca aaattttgat
    19681 gttttaggtg gactattatt aggattaacc gtaggtggtt ttttacttgg tattacgctt
    19741 tcagaaatgt atggtttgat ttctatacaa acaaccacaa gtttttctat atctatgata
    19801 gctttaatag tgttaatata tcgcgtgatt aatgttaaaa atccttttat ccctccagtt
    19861 atattgaaga accgtttata tgtaagctca attttcattg tatttctttc aatgtttgct
    19921 tatgtctcta tgcttgtttt tattccatta ttagttgttg aggttaatgg gttaagtact
    19981 ggacaggcag gcttaatatt actttctggt ggtgtcgctg ttgcaatcct ttcaccaata
    20041 gtgggaagat tatctgacaa agtgcatcct aaaatactat tattagttgg actaattatt
    20101 atgggcttat cttctttata tatgagcttc gtagcaggcg catcacctgt attattatct
    20161 atcgggagtt tagggatagg tatcgctttt gcatttatta actctccagt gaataatgtt
    20221 gcagtacttg ctttacctaa agaacaagtt ggtgtaggta cggggttgtt tcaaggtgca
    20281 atgtatcttg gggcaggaac aggtgcctca ctaatagggg ctttattgtc aatgagacat
    20341 ggggttaaag catcttttaa tcctttttat actttaactg ccccgcacta ttctgatata
    20401 tttttaacca ttacgtgcat cgtgttagtt gctttaattg ttactttaaa tataagtagt
    20461 agggatttaa agcaataaaa cctttttatt acacagatat acatctgttt ttaaatatta
    20521 ttcagaaact aaattgttaa tagcaagaac aactaaataa ttttaaaaaa cagggcttat
    20581 taacaagccc tgttttgcat tttagccaag aaaataacca gtttctgtac actatctaac
    20641 tatcactttt ttcaattcat aatattgtat agcattccat acgtttcatt ttctcattta
    20701 ttaagtaaaa tcattctaat ttagcaagta aagtcacaac ggtcttagaa tgcgcctctc
    20761 aaacgtcaaa atacaaaaaa gcgcctataa ataggcgctt tttatgatta tcgttgcaaa
    20821 gcttgctgtt ctttttttac tcttggttgc ttcaaatctg ggttagcttt tgcaaagtct
    20881 tttaattgtt gctgggtctt ttgactaatt tcgattttaa ctttgtttag ttgttcctgt
    20941 atttgttgtt tatttgcacc tggctctttt aacttatcat gcaatgcttt gtattgatct
    21001 gataaggctg gttgtttttg tgtggcttta ttatcaagaa tcttagtgtt ttcctgatat
    21061 ggattgttca aatcaggttc tacaagttca ctaccgtata agttgttttg ataataacta
    21121 aacacattat atgatttttc tatgttgact aaatcttccc atgtaacatt ctttttactg
    21181 ctgtcgattt tatcttctgg taaatcatat aatataaagc tggcttttat agcgcttttt
    21241 aaatcattgt tataaagctt ttgcatagct tcaactgggt tgtttgcttt aacaattagt
    21301 tcagattttg cgattgtttt tatagctttt tcttccaagg attttatatc aacatcacta
    21361 acaaactttt tactttgttc tggttttgtt agtttctgat taacgatttt aatatccttt
    21421 ggattaaata caacgtattc tttggaatta tcatagtatt caacatctaa ttctgcatag
    21481 tgaataccca tttcatttaa aacaggaatt agtgtttctg ctccactatc gttaccgcct
    21541 aattgattgt ttatgccatt gataatgctt aaatcatcag tatcatcaat aatcttttca
    21601 gctatattat aagcaatttt tttgttgcct gcgtccattg ctgtttcact agttggttct
    21661 tcccaatcgg acaagatgta ggggtattct tcttcatcaa tctgtttctg tgctatcttt
    21721 tcaattattt tagcgacttg attagttgtt aatgtaactt tgctggcgtt caaaggtgta
    21781 ctattttgta gttcatcatt caattcaata gtatacaaat agccgtcatt atctgcataa
    21841 gatttagctc tttgcaagct atcagttaga taagttccaa agcctaatgt tccaccattt
    21901 ttatgaaatc ttggtatttt aaattcagta aaatcctctt ttgacccatg atataaattg
    21961 tctattttac ttcgcttttc agttgtagta ttttctttaa tgatgtgatt atcatttaaa
    22021 ggtaagctat tgaatcccat atcatctaat tcttgaattg ggttatcgct aatgtagcta
    22081 cttgtttctg gtacaataac tgtcccccat tttaaaatat cttcccattg gttctgttgc
    22141 aaagttttaa atctactatc aaataaggta gaataataga aaaagatagc aggaggaatg
    22201 acgatgaatc attttaaagg aaagcaattt cagcaggatg tgattattgt agccgtgggc
    22261 tactatcttc gttataacct tagctatcgt gaagttcaag aaatcttata tgatcgtggc
    22321 attaacgttt ctcatacgac gatttatcgt tgggtgcaag aatatggcaa actactctat
    22381 caaatttgga aaaagaaaaa taaaaaatcc ttttattcat ggaaaatgga tgaaacgtac
    22441 atcaaaatta aaggaaaatg gcattatttg tatcgagcca tcgatgcaga tggtttaacc
    22501 ttggatattt ggttacgtaa aaaacgggac acacaagcag cctatgcttt tcttaagcgg
    22561 ttagtgaagc agtttgatga accgaaggtt gtagtcacag ataaagcccc ctctattaca
    22621 agtgccttta agaaactaaa agaatacggc ttttatcaag ggacagaaca tcgtaccatt
    22681 aaatacctga ataatttgat tgaacaagac catcgtccag taaagagacg caataaattc
    22741 tatcgaagtt tacgcactgc ctcacccacg attaaaggca tggaagccat ccgaggatta
    22801 tataagaaaa cccgaaaaga aggcactctc ttcgggtttt cggtctgtac tgaaatcaag
    22861 gtattattgg gaatcccagc ttaaatcata gataccgtaa gggattttat tctttattta
    22921 aaactttgca acagaaccac atgacaaatg caagctttgg aatttacatt attcattatc
    22981 ctgttgttgt gtgggtatgc tacttgcttt acagttacct caacttaccg atgatattta
    23041 tctatattct tgctttaggg cttgaactga tactgacacc gttaatttat gagctgttta
    23101 aaaggattcc tgtagttcgc tttttagtat tggggataaa aaaatgagca tttcttacta
    23161 tcctattaaa cgagtatagc tatcctatcg gcagtagcgt tgtctatggt tatggcttgc
    23221 ctgcatatta aaaaagggca aaagaaaaac agaggatttt acccctctgt ttcctctttt
    23281 gcgttacata ttcagtttac agttgtacaa tacttggtct ataaacaaac tgtaaagtga
    23341 gcagcttaga tgagctattg acatatgcac tcaagctctc tataattaaa atataaaata
    23401 agagagggtg agcacagtgt tattcgggaa gttttgcatt gattttggct ctacacaaca
    23461 atataagaca gagcattgtg tggagcccaa tcagataaaa tgtttatttg agaggcaggg
    23521 ctatttaaat cagaaatttg tgatttaaga gccttatttg tgttgccttt caataagcaa
    23581 actcaatgat tggatatgtg gccgtagaca atgttttgtc tacggccttt tgctgtctat
    23641 atttcatcta tgttattggc atagtgtctg aaaaagcaga gggctacgtc tatgggacgt
    23701 attgctacct ctgcttttat tttttaaatg atgatatcag agaagaaaat atatccccgc
    23761 acaggagata atcaagcaag gaaaactgta agccataaaa tgatggcttg cagtatgtat
    23821 gacgatggag gaatgataca agatgaaagg taaaaatatg aatttagcct ttgggttgga
    23881 agaaatttat gaggatgctg agtttcaaat cggagatttg gataaggtcg gtattgtcgg
    23941 cgtgaacgga gccggaaaga ccaccttgtt ccgcctgctg ttgggagaac ttgaacttga
    24001 taatggttca ctgaccagtg gaaatgcccg tattggttat ctcccacagg aaattgtctt
    24061 ggaagatgag gatattaccg tttgggattt cctttttgag ggacgtccga ttaaaaagta
    24121 tgagcaggaa ttggaagaaa tctataaaaa gcttgaaacc gcagtcaatg cagagcagga
    24181 agcactgctt gcccgaatgg gaacattgca agaacgcttg gagtatttcg acttctatga
    24241 ggcagaaaca attctgttgg agtttgcaga taaaatgagc attgatgcag aattatatca
    24301 tcgtccgatg agagagcttt caggcggaca aaaatccaaa atggcatttg ccagactact
    24361 atattcaaaa ccggaaattc tattgttgga tgagcctacc aaccatttag atgtcagcac
    24421 aaaggatttt gttataaaat acttaaagaa ttataggggt tcggtactga ttatcagcca
    24481 tgatattgat tttctaaatc ggattatcaa caaaattatg tacatcaaca aagctaccca
    24541 taaaatatct gtttatgatg gagactacta catctacaag aaaaagtatg cagaggaaca
    24601 gcggattcgt gaaatggcga ttgtacagca ggaaaaagaa ataaaggagc tttccgattt
    24661 tgtacaaaaa gcaaaacaag ccagtcagac caatcatcac ctcaaacgaa tgggtcaaga
    24721 gcgagccttg cggcttgata aaaagcgtgg agagctgcaa aagagaaatc gactgtacaa
    24781 gcgtgtgaag atggatattc gccccaagcg tgaaggggca caagttccct tagaggtgga
    24841 aaatatcacc ttccactatt cggggtatcc caccctttat cagaaccttt cctttcagat
    24901 taacggaaga gaacgatttc ttgtggtggg tgaaaacggt gtcggtaaat ccaccttatt
    24961 gaaattgatg atgggtattc tcagtccaga tgaaggatgc attcgcttta accagaaaac
    25021 tgatattgca tattatgcac aggaactcga acagcttgat gaaaacaaaa cggtcattga
    25081 caatgtggag tctgaaggat atacaccgtg gcaaatcaga gccgtactga gcaacttcct
    25141 gttttatgat gacgatgtaa acaagaaagt atctgtgctg tcccctggag aaaaagcaag
    25201 ggttgccctt tgcaaaatcc tattacagaa agccaatctt ttgatactgg acgagccgac
    25261 caaccacctt gacccagaaa cgcagaaaat cattggcggc aacttcaatt tgtttgaggg
    25321 aaccattatt gccgttagcc ataacccatc ctttgtggaa caaatcggaa ttagccgtat
    25381 gcttattttg cccagcggtc gaattgaacc ctattcccgt gagctgcttg agtattatta
    25441 tgaaatcaac ggttctgttg caaagtttta aatctactat caaataaggt agaataatag
    25501 aaaaagatag caggaggaat gacgatgaat cattttaaag gaaagcaatt tcagcaggat
    25561 gtgattattg tagccgtggg ctactatctt cgttataacc ttagctatcg tgaagttcaa
    25621 gaaatcttat atgatcgtgg cattaacgtt tctcatacga cgatttatcg ttgggtgcaa
    25681 gaatatggca aactactcta tcaaatttgg aaaaagaaaa ataaaaaatc cttttattca
    25741 tggaaaatgg atgaaacgta catcaaaatt aaaggaaaat ggcattattt gtatcgagcc
    25801 atcgatgcag atggtttaac cttggatatt tggttacgta aaaaacggga cacacaagca
    25861 gcctatgctt ttcttaagcg gttagtgaag cagtttgatg aaccgaaggt tgtagtcaca
    25921 gataaagccc cctctattac aagtgccttt aagaaactaa aagaatacgg cttttatcaa
    25981 gggacagaac atcgtaccat taaatacctg aataatttga ttgaacaaga ccatcgtcca
    26041 gtaaagagac gcaataaatt ctatcgaagt ttacgcactg cctcacccac gattaaaggc
    26101 atggaagcca tccgaggatt atataagaaa acccgaaaag aaggcactct cttcgggttt
    26161 tcggtctgta ctgaaatcaa ggtattattg ggaatcccag cttaaattat agataccgta
    26221 agggatttta ttctttattt aaaactttgc aacagaacca actagactgt gcaaaataga
    26281 gacacttgaa aaatctatcg ggggtcagaa acttaatagt ttttgacaca taaacaaaat
    26341 cgcgatataa tggggttgag agtgtttcat aaacttatgt cataaagtta aggagatttc
    26401 gcatgatttt agagaataaa ttgggattaa ccaatcaagt tgagttggct aaggttgaag
    26461 aaaaactcag taaacaaaaa gcgaaagaat tgtacgattg tggaaaaata aatgaaatcg
    26521 aagttggtac atttaaaggt ttatctgaaa ttcatgaatt tctattttcg gatatttacg
    26581 attttgccgg aaaaatccga tcggtcaata ttgcaaaagg aaattttcga tttgcaccag
    26641 ttatgtattt agaacattcg ttacagcata ttgatcagat gccacaaact tcttttgaag
    26701 agattatcaa gaaatatgtg gagatgaata tcgctcaccc atttcgagaa ggaaatggcc
    26761 gaagtactag aatttggctg gatctcattt taaaggaaga attgcaaaaa gttgtagatt
    26821 ggaacttaat cgataaagca gactatcttt ctgcaatgga gcgaagtccc ataaacgatt
    26881 tggaaatacg ctatctaatt tccaatgctc tgactgataa aattgacgat cgcgagttat
    26941 atatgaaagg aatcgatgtc agctatttct atgaagggta ttctgagtat acgatagatg
    27001 atttgtaaaa gtaggtggac caaatgacga aatatggata tgcacgtgtc tcaaccgctt
    27061 ctcaaagtac aaaagaacaa attcaacagt tgcttgagaa cggcgtagag aagaagaata
    27121 ttttttcaga aaaatttacg ggtacaaaac gggatcggcc aaaattcaat cagctgttgg
    27181 ctggtctgaa gcctggagat gaaatagttg ttacgaagct tgatcgattt gctcgtaaca
    27241 cgagagaagc attagagatc attgaacctt tactcgatga taacgtaacg atcaaggttt
    27301 tgaatctagg aacgattgaa aatacgtcca tggggcgaat ggtgacacgg acgttgttga
    27361 gtgtagcaga aatggaacgt gatatgattg tggaacgtac ccaagaagga aaaatgtttg
    27421 caagaaagaa taatcctaat ttcagagaag gacgtccgaa agcaacaatc acaccgaaga
    27481 agaggcacgc atatgaactg cttacttcag gtaaatcgta taaggaagtt gaagctataa
    27541 ccggtttcag tcgcagtacg ctttttagaa taaagaagaa aattgaagaa agttaaaaaa
    27601 gaagtctcag cgaaccagac aggtaaatac ttaatgcgtt ctagatatga gtctattagc
    27661 atgttgtgaa atataatatt tttttattta cttgatttct gctcaaaaaa tgtgtatggt
    27721 aactgtaaaa ggtaaagtaa ttaaaggtat gctagccacg cttactatat taggatacca
    27781 tcatatattt ataatgaacg atttgttcgt ctaccaaaca acacatatcg ttcagcgtaa
    27841 gtcacgttta ggaacgtggc ttttttagtg ttattatcga taaataatct attgactcta
    27901 ttgattttat ctccatatcc ctacggtgtt gattgtcttt agatctttca tttaagaacc
    27961 aaataactat cataaaaatc agcactgctg ctaaggttct gttgcaaagt tttaaataat
    28021 ttgatttgtc aaattaagct agacaaaata tcttcattca tgtaactcat aaatacttcc
    28081 aggggtgttt gataatccaa ggactttcgt ggaatattgt ttctcttatt cgccactgaa
    28141 gagataaaag cttggtcgac ttgattaaaa tccatgtttt ttggcagacc atcttttcgc
    28201 agcaagccat tggaattttc attcagtgct cgttgcgaag gagtccctgg atcagcgaaa
    28261 taaatagcga tgtcatgttg gttacttaaa gccttccaat tagagaattc tttcccacaa
    28321 tcaaaggtaa tggatttaaa taaatgtctg ggaatcgatc caaaccagtg gttcagagta
    28381 ttctcaatat cgatcgcctt gcgcccctcg ggcttcaagg tgatgatgat tttcgataga
    28441 cgttctacca aagttatgac agcactctta tgatgaatgc ctacaatggt atcgccttcg
    28501 atatggccga actcttcttt aaatgtcggg taatcagttt ctctttcaac gatattccgt
    28561 ttaaaagcct gttttcctcg gcgttcttga tgtccatttg gtttccgctt acccttcatg
    28621 ggcaaagtcg attcatcgaa caccttttcc ttgaactggc gataaagggt tcttacggaa
    28681 cagctgattg gtttctcttt acgcccaatg ataacgtctg gcgtccagcc ttgggcaatt
    28741 ttttctttaa tgtaggactg ttgtttcttt ggcaagacga tgtttcgtct gccacaccgt
    28801 ttcttatttt ctttatactg ttggtagtat tcgagggccg tatggccttc tttcaagaaa
    28861 ttaatgacgt tataaatcgg tgttcgagat cgtttcaggt actcagcaat tttcacaatt
    28921 ttgatgtttt ggtggtagta agactctatc atcaccagtt catccgtggt aagatgggtg
    28981 taggtcattc gtgatcactc ctatgttttc tttagtcgga attacatttt gagtgtagca
    29041 cgaatggctt atttatttgt ctagcttaat tttacaatcg gcgtaaagaa taaaatccct
    29101 tacggtatct atgatttaag ctgggattcc caataatacc ttgatttcag tacagaccga
    29161 aaacccgaag agagtgcctt cttttcgggt tttcttatat aatcctcgaa tggcttccat
    29221 gcctttaatc gtggtagagg cagtgcgtaa acttcgatag aatttattgc gtctctttac
    29281 tggacgatgg tcttgttcaa tcaaattatt caggtattta atggtacgat gttctgtccc
    29341 ttgataaaag ccgtattctt ttagtttctt aaaggcactt gtaatagagg gggctttatc
    29401 tgtgactaca accttcggtt catcaaactg cttcactaac cgcttaagaa aagcataggc
    29461 tgcttgtgtg tcccgttttt tacgtaacca aatatccaag gttaaaccat ctgcatcgat
    29521 ggctcgatac aaataatgcc attttccttt aattttgatg tacgtttcat ccattttcca
    29581 tgaataaaag gattttttat ttttcttttt ccaaatttga tagagtagtt tgccatattc
    29641 ttgcacccaa cgataaatcg tcgtatgaga aacgttaatg ccacgatcat ataagatttc
    29701 ttgaacttca cgatagctaa ggttataacg aagatagtag cccacggcta caataatcac
    29761 atcctgctga aattgctttc ctttaaaatg attcatcgtc attcctcctg ctatcttttt
    29821 ctattattct accttatttg atagtagatt taaaactttg caacagaacc atatttagta
    29881 tagtaaaaac tagaaacaat aaaatttgtg aatgttgtat acccccaaac aatacacata
    29941 ttttgaagga ttaggattaa taaagctaaa aatatagtaa gtatactaaa tatatttact
    30001 atatctagta tacttactat attttaatct tttgatcgtc tattatatat aatccgttcc
    30061 tcgtcgttta aagtatcaac ataggcgtcc attgcaagtt tgactatttc atacatagga
    30121 atatcttttg cataactaag atcccgaatg gtttttagta cgggaggatc tacttgaact
    30181 ggttttcttt ctttcgcagt gtactttcgt tcccctaact cgacattaat atcatcttta
    30241 attgaaatat cttcagcacc aattttcttc ttatctttgt tcgttggtaa taatgccatt
    30301 tagtttaatc tcctttccaa gaggtaggat atgattggcc attgagtcag catatttagg
    30361 tgtataatca aatccttcaa tatcaccatg ttgttcatag tattcaattc tttcttctaa
    30421 ttctgtaaag atgtctgcaa aaatagccca ccatcttcga tctacataat catttaattg
    30481 gataccattc tcaccataca tttctaaccg atccgagcct ttaacaatgc ttttaaaaat
    30541 gtttgattca ccatacttat caattgtttt ttgatagttt gcgtgttgag aggaacgtcg
    30601 cactgagaaa agaacaggca aaattccaat gatttgaaga tgagactctt caaaattcgt
    30661 gacaatcgga actaaaactt tattaataaa atcttctgtt ccttccattg cgtaccgttt
    30721 taattcttgc attgcaataa tataatctgc agcagttaag aatgcacgaa ccacattatc
    30781 tgttgatggt gggcagtcga taaagatata atcgaaattt tt
//
