LOCUS       NZ_CP087353            11084 bp    DNA     circular CON 12-SEP-2023
DEFINITION  Acinetobacter baumannii strain DB003 plasmid p2DB003, complete
            sequence.
ACCESSION   NZ_CP087353
VERSION     NZ_CP087353.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN23078445
            Assembly: GCF_024749745.1
KEYWORDS    RefSeq.
SOURCE      Acinetobacter baumannii
  ORGANISM  Acinetobacter baumannii
            Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales;
            Moraxellaceae; Acinetobacter; Acinetobacter calcoaceticus/baumannii
            complex.
REFERENCE   1  (bases 1 to 11084)
  AUTHORS   Mellmann,A.
  TITLE     Sequencing of Acinetobacter baumannii genomes to construct genome
            database for SNP detection
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11084)
  AUTHORS   Mellmann,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-NOV-2021) Inst. Hygiene, University Hospital Muenster,
            Robert-Koch-Str. 41, Muenster 48149, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 90x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/12/2023 05:19:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,069
            CDSs (total)                      :: 3,975
            Genes (coding)                    :: 3,876
            CDSs (with protein)               :: 3,876
            Genes (RNA)                       :: 94
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 32 of 99
            Pseudo Genes (incomplete)         :: 61 of 99
            Pseudo Genes (internal stop)      :: 14 of 99
            Pseudo Genes (multiple problems)  :: 7 of 99
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP087353.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..11084
                     /organism="Acinetobacter baumannii"
                     /mol_type="genomic DNA"
                     /strain="DB003"
                     /host="Homo sapiens"
                     /db_xref="taxon:470"
                     /plasmid="p2DB003"
                     /geo_loc_name="Germany"
     gene            complement(join(10925..11084,1..212))
                     /locus_tag="LO008_RS20305"
     CDS             complement(join(10925..11084,1..212))
                     /locus_tag="LO008_RS20305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000504218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000504218.1"
                     /translation="MGEKVKTYAVRLDPQVAEFYDQLANSEGIRTSKLFSKILTNDFQS
                     IAVKQQADRIEDLVNRLEKRIDDFEEDNNFSEKYYEDFSGLYFMMLWLLMKNGASKDEV
                     RMIQAKGYSYADDNYKRVK"
                     /name="hypothetical protein"
     gene            complement(484..738)
                     /locus_tag="LO008_RS20390"
     CDS             complement(484..738)
                     /locus_tag="LO008_RS20390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001014301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001014303.1"
                     /translation="MNGQKIDFLRFSKQGNKYFFPCKTKHRPYVTLANFPIQDPAHAGI
                     FLSHTTHLTMTPLKALQDKDFSDFLGSQKRVQKNGLFLE"
                     /name="hypothetical protein"
     gene            1422..2372
                     /gene="repM"
                     /locus_tag="LO008_RS20310"
     CDS             1422..2372
                     /gene="repM"
                     /locus_tag="LO008_RS20310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004786597.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepM"
                     /protein_id="WP_001205343.1"
                     /translation="MRDLVVKDNALINASYNLDLVEQRLILLAIVEARESGKGINANDP
                     LEVHADSYINQFGVHRNTAYQALKDACKDLFARQFSYQEKKANGNIRNVMSRWVSQIAY
                     NDNEATVDLIFAPAVVPFITRLEEQFTKYELQQVSSLSSAYAIRLYELLIQWRSTGKTP
                     TIELQEFRKKLGVLDNEYLRMAHLKERVLELSIKQINEHTDITVKYEQHKRGRSISGFS
                     FTFKQKKKDSPSIERDPNTLELFSKMTDAQRHMFANKLSELPEMGRYSQGTESYQQFAV
                     RIAEMLQDPAQFKELYPYLKKVGYMPSNKKDTVNG"
                     /name="repM"
     gene            2365..2940
                     /locus_tag="LO008_RS20315"
     CDS             2365..2940
                     /locus_tag="LO008_RS20315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005102333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication DNA-binding protein"
                     /protein_id="WP_001096616.1"
                     /translation="MAKLSLSEVSKKFHVDRSTIYRAVRNGRLSRSSDGQFDLAEVIRC
                     FGEPEQTSQKIESSKQEGDESTKKLIAHLENEVKKYQEREERLMQQIDRMQTLIELKSV
                     APATAAPHQDATACDTKMPQHATTQQDTDNKKNNELNIAENVAVPQQETTAYHTQTLQH
                     ATLQSVAVPQHKKRGLFGRVLNAVFDND"
                     /name="plasmid replication DNA-binding protein"
     gene            2960..3103
                     /locus_tag="LO008_RS20320"
     CDS             2960..3103
                     /locus_tag="LO008_RS20320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004786602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001125246.1"
                     /translation="MPKLKDIALGIIVAPLLIPIMLIASYQDKKALKKELDECQKEKDQ
                     AS"
                     /name="hypothetical protein"
     gene            complement(3286..4113)
                     /locus_tag="LO008_RS20325"
     CDS             complement(3286..4113)
                     /locus_tag="LO008_RS20325"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_057689930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OXA-24 family carbapenem-hydrolyzing class D
                     beta-lactamase OXA-72"
                     /protein_id="WP_000713530.1"
                     /translation="MKKFILPIFSISILVSLSACSSIKTKSEDNFHISSQQHEKAIKSY
                     FDEAQTQGVIIIKEGKNLSTYGNALARANKEYVPASTFKMLNALIGLENHKATTNEIFK
                     WDGKKRTYPMWEKDMTLGEAMALSAVPVYQELARRTGLELMQKEVKRVNFGNTNIGTQV
                     DNFWLVGPLKITPVQEVNFADDLAHNRLPFKLETQEEVKKMLLIKEVNGSKIYAKSGWG
                     MDVTPQVGWLTGWVEQANGKKIPFSLNLEMKEGMSGSIRNEITYKSLENLGII"
                     /name="OXA-24 family carbapenem-hydrolyzing class D
                     beta-lactamase OXA-72"
     gene            4265..5011
                     /locus_tag="LO008_RS20330"
     CDS             4265..5011
                     /locus_tag="LO008_RS20330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005262957.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element ISAba31 family transposase"
                     /protein_id="WP_005262957.1"
                     /translation="MPRTMLTDQHWQKLKVILRNLSIHHNSNLRNFIEAILYRIRTGCP
                     WRDIPSCFGHSNSIFKRFNRWSSSGKLLRLFKLLASCPDMEWIFIDGSHVRAHQHSAGI
                     ANQSISKSVGGNSSKIHLIVDAHGNPIDFMITDGTTHDVKVAPDLISTLDLKETKVVCA
                     DKGYDSEPLREQIRKTGTKANIPKKTNSQSNNDHMDWYLYKIRHLVENMFCRLKQFRGI
                     ATRYDKLKRNYQSSVALACIFLWLPL"
                     /name="IS5-like element ISAba31 family transposase"
     gene            5282..5569
                     /locus_tag="LO008_RS20335"
     CDS             5282..5569
                     /locus_tag="LO008_RS20335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019383542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnT family toxin"
                     /protein_id="WP_000438826.1"
                     /translation="MEQYFEWDEAKNRKNQKKHDISFETASLVFEDPLRISIQDRHTNG
                     EERWQTIGRVKGVLMLLVAHTIFDEDDCEIIRIISARQVTKAERNKYEHG"
                     /name="BrnT family toxin"
     gene            5556..5870
                     /locus_tag="LO008_RS20340"
     CDS             5556..5870
                     /locus_tag="LO008_RS20340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006582675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnA antitoxin family protein"
                     /protein_id="WP_001983304.1"
                     /translation="MSMVRYSHKELNEKFGEKQDAEIQRLLAKGTVPDDQLDLSDIPEI
                     TDWSNAVRQNQFYRPVKQQTSIRLDADVLAWFKAQGKGYQTRMNEILRDAMLKELKNHQ
                     "
                     /name="BrnA antitoxin family protein"
     gene            5998..>6912
                     /gene="znuD2"
                     /locus_tag="LO008_RS20345"
                     /pseudo=""
     CDS             5998..>6912
                     /gene="znuD2"
                     /locus_tag="LO008_RS20345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932945.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor ZnuD2"
                     /name="znuD2"
     gene            6996..7988
                     /locus_tag="LO008_RS20350"
     CDS             6996..7988
                     /locus_tag="LO008_RS20350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005028482.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element ISAba23 family transposase"
                     /protein_id="WP_005028482.1"
                     /translation="MAWKQTGQLSLADSLINAHKAIEELDELHNLIDWQTIEQTLRHVH
                     SSERGESAFHPVIMFKVLLLQKLYNLSDPAMEKQLARDLLFRRFVGLSLTDDVPDHSTI
                     WRYHKHLGELRLIEPLFNQINEQLAQQNIFIKAGSVSIIDASIVEAKNKRPKKGKHTDN
                     TQDNEAAYVSKKDSTGKVKTTYGFKIHLNCDEDSFVKKVETTPANVHDSQCFTTLLTDD
                     ESAVYADSAYKSQAHDDYLAEHEPPIKNHIHDRAWRNTPLTEQQKRNNTQKSQTRNTVE
                     RVFGHFKLHYGMSKARHLGLMQFHTSTLLASMVHNLKTALSLKRKYGLA"
                     /name="IS5-like element ISAba23 family transposase"
     gene            <8161..9663
                     /gene="znuD2"
                     /locus_tag="LO008_RS20355"
                     /pseudo=""
     CDS             <8161..9663
                     /gene="znuD2"
                     /locus_tag="LO008_RS20355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932945.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor ZnuD2"
                     /name="znuD2"
     gene            9968..10429
                     /locus_tag="LO008_RS20360"
     CDS             9968..10429
                     /locus_tag="LO008_RS20360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004781077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DIP1984 family protein"
                     /protein_id="WP_000761346.1"
                     /translation="MKLAEALLLRSDQQKKIISLKQRINANVLVQDGDQPSEDPNELLK
                     QVFSLIQEFQKLSYAIHETNALTKLNDGRSLLALLTLRDEFVEQHKTLTAAISNTSRES
                     DRYSTREIKWHKVIPVSSLQKQADDISLKLRDLNVLIQSTNWKIDLIEA"
                     /name="DIP1984 family protein"
     gene            complement(10752..10925)
                     /locus_tag="LO008_RS20365"
     CDS             complement(10752..10925)
                     /locus_tag="LO008_RS20365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001282484.1"
                     /translation="MSDNIIQLSKPCTLCENRQNVQLFAGLMLCGSCQENIRLTNPSMF
                     SANDEIEQKAQN"
                     /name="hypothetical protein"
     ARG             complement(3290..4113)
                     /name="blaOXA-72"
                     /gene="blaOXA-72"
                     /gene_name="OXA-24 family carbapenem-hydrolyzing class D
                     beta-lactamase OXA-72"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          1423..2372
                     /name="rep_cluster_1172"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tcctcaaaat catctattcg cttttctaat cgattcacca gatcctcaat acgatcggct
       61 tgctgtttaa cagcaataga ttgaaaatca ttggtcaaaa ttttactgaa taatttactg
      121 gttctgattc cttctgaatt agccaattga tcgtagaatt ctgctacttg tggatctaac
      181 ctgactgcat aagttttgac tttttcgccc ataaattaca cctcttatta aaattagatt
      241 ttgtacaaaa ttaaatatat ataattcaac taattaaata aaaaataata attagattac
      301 gtacaaactt atttgtacag aattaattta ttctaaaaca aaaacttatt taaatataat
      361 gcttttttta tgtacaatca tgagtacata ttttttctta aatttatcaa tatcttatct
      421 aaaaaaagtg ttgttttgat gtacaaccat gagcacagca taaaaaatag ataattcaat
      481 cacttattct aaaaaaagac catttttctg tacacgtttc tgagacccta aaaaatcgct
      541 gaaatcctta tcctgtaagg ctttgagggg tgtcatcgtt agatgcgtgg tgtgtgacaa
      601 aaaaatcccg gcatgtgccg gatcttggat tggaaaattg gctaaagtga cgtagggccg
      661 gtgcttggtt ttgcatggaa aaaagtattt atttccttgt ttagaaaaac gtaaaaaatc
      721 aattttttgt ccattcatcc aggttaaaaa tttcaaccca aaactttaat tatgaaaagc
      781 ttcatagaac gcgttcaaat gcgatttaag agcctttacc tagaaaacat agatctcata
      841 gtgaaaaaca caaaacagct caaaaaacgc aaatgagagc gaaataaaga ggtattttga
      901 ctttagatag atgcatagag cgagtgtcta cgagcgaact atcaaaattt gcgcctagac
      961 cctctgaaaa acattttttt gtcctcttta gcctaagaaa gcgtaagttt cgtgcagaaa
     1021 tttgctcctg gatcgagcgt agcgagtaaa aaagttttat gagcgaagcg aattccaagt
     1081 ttcttttgct tttttttaaa gtcacgccag tattaaccaa aaaattgccc caacgaactg
     1141 agcgaaagcg aagttcaata gagtttgagc gaagcgaaaa ccaagggcaa tttttcattc
     1201 cctgggcttt taattatttt aaagttttta aatactttta aatggcttga aagccttatg
     1261 aataaagggt tttagctctt atatgtccac gtttaccttg caatatgtcc acgtttacct
     1321 tgcaatatgt ccacgtttac cttgcaatat gtccacgttt accttgcatt agtacacaaa
     1381 taatattaac gtgtacttat acacaataaa aaatagtggc tatgagagat ttagttgtaa
     1441 aggacaatgc cttaatcaac gcaagctata acttagactt agtagaacaa cgtttaattt
     1501 tattggctat tgttgaagca agggaaagtg ggaaagggat taatgcaaat gatccattag
     1561 aagttcatgc agatagttat atcaatcaat ttggtgtaca ccgtaataca gcttatcaag
     1621 ccttaaaaga tgcttgtaag gatttattcg cgcgtcaatt tagctatcaa gagaaaaaag
     1681 ctaatgggaa tatccgaaat gttatgagtc gttgggtatc tcaaattgct tataacgaca
     1741 atgaagcaac tgtagactta atatttgcac ctgctgttgt tcccttcata acccgactgg
     1801 aagaacaatt tactaaatat gaattacagc aagttagtag tcttagtagc gcttatgcca
     1861 ttcgcttata tgagcttcta attcagtggc gaagcactgg taaaacccca accatagaac
     1921 tacaagaatt tagaaagaag ttaggcgttc ttgataatga atatttacgg atggctcatt
     1981 taaaagagcg tgttttagag ctttcaatta aacaaataaa tgagcatacg gatataactg
     2041 taaaatatga acagcataaa agaggacgtt ctatttcagg attttctttt acctttaaac
     2101 agaagaagaa ggatagccca tcaatagaaa gagatccgaa cactttggag cttttttcaa
     2161 agatgaccga tgctcaacgg catatgtttg caaataaact ttcagaactc cctgaaatgg
     2221 gtcgctattc acaaggaaca gaaagctacc aacagtttgc tgtacgtatt gctgagatgc
     2281 tacaagatcc cgctcaattc aaagagctat acccatacct aaaaaaagtg ggatacatgc
     2341 catcaaataa aaaggacacc gtaaatggct aagttatcac taagtgaagt atctaaaaaa
     2401 tttcatgtgg atagatcaac catttacaga gctgtacgta atggacgttt atcacgctcc
     2461 agtgatggac aattcgatct agcagaggtc atacgatgct ttggagaacc tgagcaaaca
     2521 tctcaaaaaa ttgaatcatc taagcaagaa ggtgatgaat ctacaaaaaa acttattgcc
     2581 catttagaaa atgaagtcaa aaaataccaa gaacgtgaag aacggttaat gcaacaaatt
     2641 gaccgtatgc aaacactcat tgagctgaaa agtgttgcac ctgccacagc agcaccacac
     2701 caagatgcta cggcatgcga caccaagatg ccacagcatg cgacaacaca acaagacact
     2761 gataacaaaa agaataatga attaaatatt gcagaaaatg tagcagtgcc acagcaagaa
     2821 actacggcat accacaccca aacgctacag catgccacgt tgcaaagtgt ggcagtgcca
     2881 caacacaaaa aacgtggttt atttggccgt gtgctgaatg ccgtctttga taatgactga
     2941 gcaataaggg tgaaagatca tgccgaaact gaaagacatt gccctgggaa ttattgtagc
     3001 tccgctgctg atcccgatca tgctgattgc atcgtaccag gataaaaagg cgctgaagaa
     3061 agagctggat gaatgccaaa aagaaaaaga ccaggcatcc tgattattca attgagctaa
     3121 tcaaaagtgt ggaacattga tgaaataata gcgtggaacg tgaaaagtca taaaaaaagc
     3181 ccgaacaggg atgctcgggc tataaactag aaactacagc gttgaattat aaggataatt
     3241 atacagcatt tcgtataagg cgtattatgt taattttaga aattattaaa tgattccaag
     3301 attttctagc gacttataag taatttcatt acgaatagaa ccagacattc cttctttcat
     3361 ttctaagttg agcgaaaagg ggattttttt tccattagct tgctccaccc aaccagtcaa
     3421 ccaacctacc tgtggagtaa catccattcc ccatccactt tttgcataaa tcttactacc
     3481 atttacttct ttaattagaa gcattttttt aacttcttct tgagtttcta atttaaaagg
     3541 taatcggtta tgtgcaaggt catcggcaaa attaacttct tgtactggtg taattttaag
     3601 ggggccaact aaccaaaaat tatcgacctg tgttccaata tttgtatttc caaaattaac
     3661 ccgctttact tctttctgca ttagctctag gccagtccgt cttgcaagct cttgatatac
     3721 tggaactgct gacaatgcca ttgcctcacc taaagtcata tctttctccc acataggata
     3781 agttcttttt ttaccatccc atttgaaaat ctcatttgtt gttgctttat gattttctag
     3841 cccgattaaa gcatttagca tcttaaatgt tgatgcaggg acatattctt tatttgctcg
     3901 tgcaagagca ttaccatagg tgctaagatt tttaccctct ttaataataa ttacaccctg
     3961 tgtttgagct tcatcaaaat agcttttaat agctttttca tgttgctgag aagaaatatg
     4021 aaaattatct tcagatttag ttttaataga tgaacatgca ctgagagaaa ctagaataga
     4081 aatgctgaat ataggaagta taaatttttt cattacaaat tcatgttagg ggaaattttg
     4141 gggcttagag tataatattt ttattaaaaa agttaaaact cttttagggt gtgttgacac
     4201 ttttagctta aaaaaatagc gaagtagtaa aatcaaatca ccaaacccaa ttttactatt
     4261 cgctatgcct cgtaccatgc tgacagatca acactggcaa aagttgaaag ttattctgcg
     4321 taatttatcc attcaccaca actcaaattt acgcaatttt attgaagcta ttctctatag
     4381 aattagaaca ggctgtccgt ggcgagatat tccttcttgt tttggtcatt ccaactctat
     4441 tttcaaacgt tttaatcgtt ggtcaagcag cggtaagtta cttagattat tcaaattact
     4501 agcctcatgc cccgatatgg agtggatttt tattgatggc tctcatgtac gtgctcatca
     4561 acattctgcc ggcatagcga atcaatctat ttctaaaagt gtaggaggaa actcctcaaa
     4621 aatacatttg attgttgatg cacatggcaa tcctattgat ttcatgatta ccgatggaac
     4681 cacacatgat gttaaagttg cgcctgattt aatatcaaca ttagatttaa aagagacaaa
     4741 agtggtatgc gcagataaag gctatgattc agaaccactg cgtgaacaga tcaggaaaac
     4801 agggactaaa gcgaatatac caaagaaaac gaatagccaa tcgaacaatg accatatgga
     4861 ctggtattta tataaaatca ggcatttagt tgaaaatatg ttttgtagat taaagcaatt
     4921 tagaggaata gctactcgat atgacaagct caaaagaaat tatcaaagtt ctgttgcctt
     4981 agcctgtata tttttatggc tacctttata gggttaatta tgaacagtaa gtgtcaacag
     5041 accctaattt aacataatgg cgattatacg aagtacactt gtatattaat ataaatatca
     5101 actacttaat aaaaatagaa aaatcccaaa atgcccaaaa agccgacttt gaaacaagtc
     5161 ggctttttta tgagcagttt tgatacttct tgccaataat tttgactaaa aattacacga
     5221 atctggttga gtgatacaat tttgtgatac attattgtat atacaaattt gaatgttttt
     5281 tatggaacag tattttgaat gggatgaggc taagaatcga aagaatcaga aaaagcatga
     5341 tatctctttc gaaactgcaa gccttgtttt tgaagatcca ttacggatct caatccaaga
     5401 cagacatacc aatggtgaag aacgttggca aaccattgga cgagttaaag gcgtactaat
     5461 gttattggtg gctcacacca tttttgatga agatgactgt gaaatcatcc gaatcattag
     5521 tgcaaggcaa gtcactaaag cggagcgaaa caaatatgag catggttaga tactcacaca
     5581 aagagctgaa tgagaaattt ggtgagaagc aagatgctga aattcaacgc ttgcttgcta
     5641 aaggcacggt tcctgatgat cagctagatc tatcagatat tcctgaaatt acagactgga
     5701 gcaatgctgt acgccaaaat caattttacc gcccagtaaa gcaacaaact tcaattcggt
     5761 tagatgctga tgtacttgct tggttcaaag cacaaggcaa aggttatcaa acacgtatga
     5821 atgaaatttt acgagatgct atgctaaaag aattaaaaaa tcatcaataa gaatgggagc
     5881 ttaggctccc atttttgact tcatttttag gggggattac cattcaaaaa tttaaatagt
     5941 agattttata aatttttaag tgttatatta taatataaca ttaaatttgg ttgttttatg
     6001 ctaaataaaa gtaaactatt tttagcttta attactttag gggcctcgaa aattttattg
     6061 gcagctgaag ggcctgttac taccttaaat acaatagtat taactgcaca atctgatgag
     6121 ttagggtctg agctgttagg caaaagtcta aatgttagta atcagtttat tgatactagt
     6181 aaacttaaac agcgttcgac aactctaggg gatgccttgg gtacggaatt aggaattcat
     6241 tctaatcaat atggaggtgg agcatctact cctattattc gtgggcagga aggaaaacgt
     6301 attaaagttt tacagaataa tgctgacgtg ttggatatgt ctaatatgtc cccagatcac
     6361 gctgtcacag ttgaaccaag tttagctaag tctattgaaa ttatacgtgg tgcaagtacc
     6421 cttttgtata gttcaaatag tgcggcaggg gtagtcaatg tcattgacta taaaattcca
     6481 acccaaatgc ctcaagacgg attagagggt aatactacat tacgttttaa tactggcagt
     6541 aatgagaagt tgaccacagc aggtgtaaca gttggcttaa gcccacatgt agctttacgg
     6601 gcagaagggt tatatcgtaa tgctggtaac tataaaactc ctcattacca gtctagctct
     6661 tataattctt tagaagatct tgaaaaccaa aacagtattt ataaaaattt aaaatattta
     6721 ccagaaagct gggcagagtc gagagtaggt acgcttggat tatcctggat agacgataat
     6781 acttatttag gagtttctta tacacatcgt catgatgaat atggtttacc agcccatagc
     6841 catttatatg aaggttgtgg tgcctctgca atcggtatcg attcacgaat tagtggatta
     6901 aaaaattatc tgaaaccttt gcacgaataa acacacaaaa gtccattaaa ttggtataat
     6961 acaataaaat caatcaccta gcaaaagaca cgactatggc atggaaacaa acagggcaac
     7021 tctccctagc agacagtctc attaacgctc acaaagccat cgaagaatta gatgaactac
     7081 acaacctaat tgactggcaa actatcgagc aaaccttacg ccacgttcat agcagtgagc
     7141 gtggggaatc tgcctttcac cctgtcatca tgtttaaagt attactctta caaaaactct
     7201 ataacctatc ggatccagcc atggaaaaac aactggcacg agacttacta tttcgtcgct
     7261 ttgttggcct atcattaacg gatgatgtac ccgaccatag caccatttgg cgataccaca
     7321 aacacctagg tgagcttaga ctgattgaac cattgttcaa ccaaatcaat gagcaactag
     7381 cccaacaaaa catttttatc aaagcgggca gtgtcagcat catcgatgcc agtatcgttg
     7441 aagctaaaaa caaacgacct aagaaaggca aacacaccga caatacccaa gataacgaag
     7501 ccgcctatgt cagtaaaaaa gacagtacag gtaaagtaaa aaccacctac ggctttaaaa
     7561 ttcatctcaa ctgtgatgaa gacagctttg tcaaaaaggt tgaaactacc cctgccaatg
     7621 tccatgattc ccaatgtttt accacgctgt taacagatga tgaatcagcc gtgtatgctg
     7681 acagtgcgta taaaagccaa gcccatgatg actaccttgc cgagcatgaa ccaccgataa
     7741 aaaatcatat tcatgataga gcatggcgca atacaccctt aaccgaacag caaaaacgca
     7801 ataataccca aaagagccaa actagaaaca ccgttgagcg ggtctttgga cattttaaac
     7861 tgcattatgg gatgagcaaa gctcgtcatt tagggttaat gcaatttcat accagcactt
     7921 tgcttgcaag catggtgcat aatttaaaaa ctgccctaag cttgaaacga aaatacggac
     7981 tcgcctaggg ttattgtgcc tgttggttag taagctcagc caatagacac aaatttaaca
     8041 accatttgga gattttatcc atgatttagc cattgttttg cttatttcat tgccattctt
     8101 tgtttttttt cggtttggtg gtatgcctcg agcaaagggg ctgtttcgtg caaaggtctc
     8161 tatcttttat attatcctca attgatggat gagcaagata ttaattacat aaatccacgt
     8221 cctgattgtc atcagcataa tcatattcat gaaactaatt tctctcataa tgctccttat
     8281 attgatttaa atactcgacg ttatgatgtg cgtggagaat tcactcaacc atttaccggt
     8341 attgacaaaa ttcgtacctc attgagttat atagattatt ttcacaatga actcgaggga
     8401 gataagatta ctaacttttt taaaaataca ggaaaagtag gccgcataga gttatcacat
     8461 cagccattag gggaattaac cggtatcttg gggctacaat atttggaaca ggataatagt
     8521 gctttatcac cagtccattc tcaagaaggc cataccacct atctagataa tcagcagcta
     8581 ttaaatcgaa atgtcactaa aaactttagt gtatttggcc tagaaaaata taactggaac
     8641 gactttactt tcgaactagg tgctcgtata gaaaagcaga aagttagtat ggattatgat
     8701 atagaaaaaa ttaaagattc aatgaaacct tggcctaata aatataacag tccttatgta
     8761 gaaaaaaata ataaaatcag ggctcaaaat ttaaaatcta ttttagaagc tgttcaacct
     8821 aacaaagaaa cagctttttc ttatgcaggt acagtccact ggagatttgc tccaaattat
     8881 atcttatcat taacaggtac acatcaagaa agattaccta atgcacaaga aatgtatact
     8941 catggtatgc atctcgctac taattctttt gaaataggta accgctttct aagaaaagag
     9001 aaatccaata atttagaaat cagtctggcc tataaggatg atttacttga ttatcaaatc
     9061 agtacttact attatgattt tgataactat atatatttac agacactcaa tgaagtttta
     9121 ggaactacaa aagttagaga tcagcataca ctacgtatta atcattatag ccagtctgct
     9181 gctaattttt atggattaga gggcaacata gggtatcaat ttaattctgt ttatcacggc
     9241 tctctttttg gagattatgt gaaaggccgt ttaacaaatt tacctgatgc tgtaattgca
     9301 tacgatatct ggaatagaga accgacttta gctccccaaa aggatcgtta cactcctaga
     9361 ttacctcctg ctcgtttggg tacacgacta aaagctgatt ttgatgaatc gcttaaaggt
     9421 gaaatagaat attatcgagt ctttaaacaa gataatattt ctaaatttga gcaggttaca
     9481 tcaggttata atatgcttaa tatgacttta gcatataaaa ataagctatc tcacacagaa
     9541 tatgatttat tctttaaagc gaataattta cttgatcaga aagtctatgc ccatgaaaca
     9601 tttttgccat atattcccca aattggaaga aattttagtt taggcttaaa tcttaatttc
     9661 tagataagat actgtaatct tctaagaaaa tttcttagaa gatttttctt ataaaatgat
     9721 tagattaata attaaggtaa gcgtccgctg aatcccatac ctatttttta attcgattta
     9781 ggtttccagc agtgtggcag taactcttca atctgggtca ctttatgtgt cggcagcctt
     9841 ttcagcactg aatagccacc gattttgtag acacctttta gctagataaa aagcaatttt
     9901 tttgatcttt aaagaatgag gatataagct gtttaaaact taattctaat tggttaatag
     9961 gtgaaaaatg aaattagcag aagctctctt acttcgaagt gatcaacaaa aaaaaattat
    10021 ttcactaaaa caacgtatca atgcaaatgt attggtacaa gatggtgatc aaccatctga
    10081 agatccaaat gaactactaa aacaagtatt ttctttaatt caagaatttc aaaaattaag
    10141 ttatgcaatt catgaaacta atgctttaac aaaattaaat gatggccgtt ctctacttgc
    10201 tttattgact ttgcgtgatg aatttgtaga acagcacaaa accctaactg cagcaataag
    10261 taatacatct cgtgaatctg atcgttatag tacgcgggaa ataaagtggc ataaagttat
    10321 tccagtttca tcattacaaa aacaagctga tgatattagt cttaaattac gtgatttaaa
    10381 cgtgttaatt cagtcgacta attggaaaat tgatttgatt gaagcctaat agtcctttag
    10441 atataatcaa gttgaacata ctgggcgagt acaagatccc ttacttccac aacataggat
    10501 tgtaaataaa gtgtagtggc ttgcaaagca agtggataag cttaaaattt taagtacaaa
    10561 tcaatccatc acttggcata actcaaatct ttgtgcaaac aaagttacac gttacttata
    10621 actaccatgt actgacagta tgttcacctc aattactaaa aataaagaaa tgaacaagca
    10681 tcagctcaac tacatttcta tttttaattc agttcggcat ttaacataaa atctcttata
    10741 cgaagcccag gttaattctg ggctttttgt tcaatctcat cattggccga gaacatactt
    10801 ggattcgtaa gcctgatatt ttcctgacaa cttccacaca gcatcaatcc tgcaaaaagt
    10861 tgtacatttt gtctattttc acaaagcgta catggctttg aaagctgaat aatattatct
    10921 gacactactt taccctctta tagttatcat ctgcatatga ataaccttta gcttgtatca
    10981 ttctaacctc atctttagaa gcgccatttt tcattaagag ccacaacatc atgaaatata
    11041 gtccagaaaa gtcttcatag tatttttcag aaaaattgtt atct
//
