LOCUS       NZ_CP087270             8413 bp    DNA     circular CON 11-MAY-2024
DEFINITION  Aeromonas veronii strain HD6448 plasmid pHD6448-4, complete
            sequence.
ACCESSION   NZ_CP087270
VERSION     NZ_CP087270.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN20179696
            Assembly: GCF_022921155.1
KEYWORDS    RefSeq.
SOURCE      Aeromonas veronii (Aeromonas ichthiosmia)
  ORGANISM  Aeromonas veronii
            Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
            Aeromonadaceae; Aeromonas.
REFERENCE   1  (bases 1 to 8413)
  AUTHORS   Du,H.
  TITLE     Complete sequence of strain HD6448
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8413)
  AUTHORS   Du,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-NOV-2021) Department of Clinical Laboratory, The
            Second Affiliated Hospital of Soochow University, SanXiang, Suzhou
            215004, China
REFERENCE   3  (bases 1 to 8413)
  AUTHORS   Du,H. and Yang,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUL-2021) Department of Clinical Laboratory, The
            Second Affiliated Hospital of Soochow University, Sanxiang, Suzhou
            215004, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. v3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022921155.1-RS_2024_05_11
            Annotation Date                   :: 05/11/2024 05:15:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,942
            CDSs (total)                      :: 4,781
            Genes (coding)                    :: 4,618
            CDSs (with protein)               :: 4,618
            Genes (RNA)                       :: 161
            rRNAs                             :: 11, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 11, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 122
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 163
            CDSs (without protein)            :: 163
            Pseudo Genes (ambiguous residues) :: 0 of 163
            Pseudo Genes (frameshifted)       :: 42 of 163
            Pseudo Genes (incomplete)         :: 130 of 163
            Pseudo Genes (internal stop)      :: 15 of 163
            Pseudo Genes (multiple problems)  :: 23 of 163
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP087270.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..8413
                     /organism="Aeromonas veronii"
                     /mol_type="genomic DNA"
                     /strain="HD6448"
                     /isolation_source="hospital sewage"
                     /db_xref="taxon:654"
                     /plasmid="pHD6448-4"
                     /geo_loc_name="China:Suzhou"
                     /lat_lon="31.30 N 120.58 E"
                     /collection_date="2019-06"
                     /collected_by="The Second Affiliated Hospital of Soochow
                     University"
     gene            complement(1021..>1272)
                     /locus_tag="KXU59_RS24575"
                     /old_locus_tag="LOS88_24575"
                     /old_locus_tag="LOS88_RS24575"
                     /pseudo=""
     CDS             complement(1021..>1272)
                     /locus_tag="KXU59_RS24575"
                     /old_locus_tag="LOS88_24575"
                     /old_locus_tag="LOS88_RS24575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138014.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /name="Tn3 family transposase"
     gene            complement(<1261..1641)
                     /locus_tag="KXU59_RS24580"
                     /old_locus_tag="LOS88_24580"
                     /old_locus_tag="LOS88_RS24580"
                     /pseudo=""
     CDS             complement(<1261..1641)
                     /locus_tag="KXU59_RS24580"
                     /old_locus_tag="LOS88_24580"
                     /old_locus_tag="LOS88_RS24580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220837.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /name="recombinase family protein"
     gene            1974..3632
                     /locus_tag="KXU59_RS24585"
                     /old_locus_tag="LOS88_24585"
                     /old_locus_tag="LOS88_RS24585"
     CDS             1974..3632
                     /locus_tag="KXU59_RS24585"
                     /old_locus_tag="LOS88_24585"
                     /old_locus_tag="LOS88_RS24585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019752930.1"
                     /GO_process="GO:0006935 - chemotaxis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="WP_103260121.1"
                     /translation="MSDWLTRFSIKTRLISLLILLAATAAGLTMEGLNGMRSSNADINQ
                     MYNNVLLPLDKLGDLTNHMHHARTQLLLALQHQPGSAFEKAHDHPASMHFDAVDRSVGS
                     MRERLADYQRMPMSKEHQRLATELQNKLSDYLDNGVQPTLNAMRQGDYAGGNAILLNRL
                     QPAFMTTYASVRNLVESEQESANASYQRAKESFDRLVVIIGLTLVVALFLATVVALATV
                     SGITKAVRELQVGGQQLADGNLGYRVTYQGRDELGEISSSFNAMASRFHHTIQELAGAV
                     EQLAAAAEQTAQISTETSDGIRRQQLETDQVATAMNEMSATVQDVAGNAASAARAAQEA
                     DQQSESGKLVVHQTISSIDSLASEVEHAATVIHELEADSAGISSVVDVIRSIADQTNLL
                     ALNAAIEAARAGEQGRGFAVVADEVRSLASRTQQSTSEIQTMIEKLQGGANRAVAVMQS
                     SCTKAQAGKQQVASAGHMLDQISNAVAIINDMNAMIASAAEEQSSVAEEINRNVTSVSQ
                     IAEETSEASRQNVATSKQLSALATQLQRLVHMFRL"
                     /name="methyl-accepting chemotaxis protein"
     gene            complement(<3632..3901)
                     /locus_tag="KXU59_RS24590"
                     /old_locus_tag="LOS88_24590"
                     /old_locus_tag="LOS88_RS24590"
                     /pseudo=""
     CDS             complement(<3632..3901)
                     /locus_tag="KXU59_RS24590"
                     /old_locus_tag="LOS88_24590"
                     /old_locus_tag="LOS88_RS24590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003281858.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /name="transposase"
     gene            complement(4015..4884)
                     /locus_tag="KXU59_RS24595"
                     /old_locus_tag="LOS88_24595"
                     /old_locus_tag="LOS88_RS24595"
     CDS             complement(4015..4884)
                     /locus_tag="KXU59_RS24595"
                     /old_locus_tag="LOS88_24595"
                     /old_locus_tag="LOS88_RS24595"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001736514.1"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]; GO:0046872 - metal ion binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_223198360.1"
                     /translation="MDMFQEARLGKAVDPSTTLPLVGEIAASVLRQPHALISVARIKTH
                     DDYTYLHSVAVCALMLSLARHLDLDEEQTRLAGIGGLMHDLGKAAMPLEVLNKPGKLTD
                     AEFAIMKRHPVEGAKMLRAGGAEPGVVDIALHHHEKIDGTGYPDRLAGDAISLLARMGA
                     ICDVYDAVTSERAYKKPWDPSAAMRQMAKWEGHFDKRIFHAFVKAVGIYPVGSLVRLSS
                     QRLAVVVEPGMESLLTPKVRVFFSLRSREPIPMQTIDLAATSCKDSITGPEDPTLWNFK
                     NLDDLWME"
                     /name="HD-GYP domain-containing protein"
     gene            complement(4968..5207)
                     /locus_tag="KXU59_RS24805"
     CDS             complement(4968..5207)
                     /locus_tag="KXU59_RS24805"
                     /inference="COORDINATES: protein motif:HMM:NF023299.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3391 domain-containing protein"
                     /protein_id="WP_345742622.1"
                     /translation="MYIHKLAGSWFRHPFWRGSFLLTEPQDLSAIRECGVGEVWVDLAK
                     SQVDPESPESPESPEPRAQSPENCRRSNLCRLVH"
                     /name="DUF3391 domain-containing protein"
     gene            complement(5506..5730)
                     /locus_tag="KXU59_RS24600"
                     /old_locus_tag="LOS88_24600"
                     /old_locus_tag="LOS88_RS24600"
     CDS             complement(5506..5730)
                     /locus_tag="KXU59_RS24600"
                     /old_locus_tag="LOS88_24600"
                     /old_locus_tag="LOS88_RS24600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004577252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_063639086.1"
                     /translation="MTELERQLLKALESLEGGYRAQHAAWESAYSDLRQMFEATSTENR
                     ALRESVGSLSKQVLHLSGQVETLSQKLKP"
                     /name="MbeD family mobilization/exclusion protein"
     gene            complement(5731..6204)
                     /locus_tag="KXU59_RS24605"
                     /old_locus_tag="LOS88_24605"
                     /old_locus_tag="LOS88_RS24605"
     CDS             complement(5731..6204)
                     /locus_tag="KXU59_RS24605"
                     /old_locus_tag="LOS88_24605"
                     /old_locus_tag="LOS88_RS24605"
                     /inference="COORDINATES: protein motif:HMM:NF016710.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_063639085.1"
                     /translation="MSKILELAKTFEESSKQQASDIETSVKNAFEPHERAILAALESSA
                     RRLNTAIDAQNRRWGWLVLKGWVFPLIGVAFLLGISWVVVWYQGRVIAENWVEISRQNK
                     TLEQLAAKGGKLELSTCGKDQRLCVKMDLKELAYGREEESERGEYPWRIPEGY"
                     /name="MbeB family mobilization protein"
     gene            complement(<6242..6892)
                     /locus_tag="KXU59_RS24610"
                     /old_locus_tag="LOS88_24610"
                     /old_locus_tag="LOS88_RS24610"
                     /pseudo=""
     CDS             complement(<6242..6892)
                     /locus_tag="KXU59_RS24610"
                     /old_locus_tag="LOS88_24610"
                     /old_locus_tag="LOS88_RS24610"
                     /inference="COORDINATES: protein motif:HMM:NF015397.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(6889..7059)
                     /locus_tag="KXU59_RS24615"
                     /old_locus_tag="LOS88_24615"
                     /old_locus_tag="LOS88_RS24615"
     CDS             complement(6889..7059)
                     /locus_tag="KXU59_RS24615"
                     /old_locus_tag="LOS88_24615"
                     /old_locus_tag="LOS88_RS24615"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_164882767.1"
                     /translation="MNEYGVAEYDYTLIRLPGEQGWSLRLLKDGQEVSGEVYQEHDEAL
                     SVATVWLCSES"
                     /name="hypothetical protein"
     gene            complement(7059..7400)
                     /gene="mobC"
                     /locus_tag="KXU59_RS24620"
                     /old_locus_tag="LOS88_24620"
                     /old_locus_tag="LOS88_RS24620"
     CDS             complement(7059..7400)
                     /gene="mobC"
                     /locus_tag="KXU59_RS24620"
                     /old_locus_tag="LOS88_24620"
                     /old_locus_tag="LOS88_RS24620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005322038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="WP_063639083.1"
                     /translation="MTPAKRERVIKIRVTDEEFARLKGLSGDERLAEWMRSQCLGHDKA
                     AARRRTPVPKADPALLRQIAGIGNNLNQVARRVNSGEWGAVERVQVIAVLMAMERALQA
                     LSVPSTEVT"
                     /name="mobC"
     gene            complement(7397..7702)
                     /locus_tag="KXU59_RS24625"
                     /old_locus_tag="LOS88_24625"
                     /old_locus_tag="LOS88_RS24625"
     CDS             complement(7397..7702)
                     /locus_tag="KXU59_RS24625"
                     /old_locus_tag="LOS88_24625"
                     /old_locus_tag="LOS88_RS24625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005322034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_063639082.1"
                     /translation="MKDARDDQTLDLLPSGKRRGRPPTGKALSPAAKQAAYRARQREKT
                     VTVTLNRPDCGELEIFLLNLRDGRTSTLAPEVVARLHDAVRSAWLGQLHSGNGDQK"
                     /name="hypothetical protein"
     Typing          complement(5427..6892)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="92.025"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 cccgttctgc ccgaccttca cacccgctac ggcaacaatc acttgcgtcc aatccgagcg
       61 aatacgacaa agcgccaaag gtgaaagcct ttggtaacag ggttcgagca ggggtttgat
      121 acttgaacag tgggccgcac gcggctaaac tgagggggta cttaacggta tccgcttcct
      181 gctcgaagct gttacccacc ggattccaag gccggcaagc cgaggaacac cgggcaaaga
      241 acccgcctag ataggtgggt tttttgtttt ctggtgggca ggttacgctt gatcagagga
      301 tctgatcaag atcatttaga atacgaacct cacagaacga gcgtagagct cactcgccac
      361 ctaacccata gcatttccat agcaggaaca aaaaacgcgc catagcgcgt tttaatgaag
      421 gatccgaaga gatggaaaag gatcctgtct tgattacggc atattcgtta tcggagttct
      481 acgccgcgca acagtccccc cagccgatac agccgtctca agctgatgat cttggcgaag
      541 agaaagctga acatcgacat taaaaccaca agccgcatgc tcgtcacaga taaacgcctc
      601 tgtgtttggt gcccaaatcg ccgaagtgtc ttctcggcga agccttacag aaaaattatt
      661 tgtcgccggg ttacggcaac cggcaatgat acaggaggtc cagcacttat tctggccatg
      721 ccttcggtct atatttttta tccttaacaa ataaagactt acctcttagc tcacaacgtt
      781 cagccaaaat gtggccaact aactaaatcc ttatcatggg gtaacagggg atgtaagccg
      841 gaaccccaga aatttccgtc accctagttg ggtgggctca acactcgtgt caccagctac
      901 cttctggaga atcgagctcg gccatccctc cctggacggg catcgctcga cgatgttcaa
      961 cggctccctc acggggccgt cgttttgggg gagcccgcag aattcggaaa aaatcgtacg
     1021 ctaaggtttt ccgggcatcc gtaggggccg aaacttcccg tcttccagtc tgcggctctg
     1081 ccgccagacg taatcgccgg ttaggttgat gtgctcccag cccagcggcg acaggaattg
     1141 cagcagctcg ccgtccaccg gcttgccggc ctcgaccaac ccctgggtgg cgcgctccag
     1201 gtacaccgtg ttccacagca cgatagccgc cgtcaccagg ttgaggccgc tggcccggta
     1261 gcgctgctgc tcacagatca gcgcacgctc gaactcggcg aaggccccca tcaccgacag
     1321 catcaggttg gccatcggcg agtcctcgcc ggtgaatacc agcccctcct tcaagaactc
     1381 gatgcgtacg ccgcgctggg tcagcttctg tacaaggcgg cgcaggtcgt cgaggttgcg
     1441 ggccagacga tccatgctgt gcaccaccac ggtgtcgccc tcgcggacga agctcagtag
     1501 cgcttcgagc tgggggcgct gggtgtcctt tcccgaggct ttgtcggtga acaccttgct
     1561 cacctgggtc tgttccagct ggcgttccgg gttctggtcg aagctgctga cccggacgta
     1621 gccgatgcgg tgcccctgca cgatgtctcc ttggttgaag gcggcttaag tgctccttct
     1681 gttccgttgt gcctcaaacc ccgtttctgt caggctgaaa tctatgacct tcgcgggcat
     1741 gtgtcaaaaa atgcgaaaga tgactctatt ctgacgaagc ggcgcggcct tgcctgacat
     1801 ccagttaggg tatagcctag ccggacagcc ttcatggctt gtttttgatt taagtactaa
     1861 attgccccag accatacggc gagaagcctt gagggggagc ctgactcaag atttcaaatg
     1921 aaccagccga tacaatgaag gcacattgat atgcctaata atgaggtgaa gtggtgagtg
     1981 attggctaac ccgtttttca attaaaaccc gtctcatcag tttgctcatt ctgctagctg
     2041 ctacggctgc cggcctgaca atggaggggc ttaacggcat gcgcagcagc aatgccgata
     2101 ttaaccagat gtacaacaac gttctgctac cgctcgataa gcttggcgac ctcaccaatc
     2161 acatgcacca tgcacgcact cagcttttgc ttgctctgca acatcagcct ggtagtgcgt
     2221 tcgaaaaggc acatgaccac cccgcgagca tgcatttcga tgctgtggat agaagcgtag
     2281 gcagcatgcg tgagcgcctt gctgactatc agcgtatgcc aatgagcaaa gagcatcagc
     2341 gcttggccac tgaactgcaa aacaagctgt ctgattatct ggataatggt gttcaaccga
     2401 cgctcaatgc aatgcgccaa ggtgactatg cgggagggaa tgcaatcctg ctgaatcgct
     2461 tacaacctgc atttatgacg acctatgcca gcgtgcgtaa tctggttgag tcggagcagg
     2521 agagcgccaa tgcaagctac cagcgcgcta aagagagctt cgatcgtctg gttgtgataa
     2581 tcggtctcac gctagtggtt gctctgtttc tggccacagt cgtggctttg gctactgtat
     2641 ctggcatcac aaaagctgtt cgcgagcttc aagtcggcgg tcagcagcta gctgatggca
     2701 atttgggcta tcgagttacc tatcaggggc gtgatgagct gggcgaaatc tctagctcat
     2761 tcaatgcaat ggcttcgcgt tttcaccaca ccattcaaga gttggcgggg gctgtggagc
     2821 aactggcagc cgcagctgag cagactgctc agatcagcac tgaaaccagt gacggcatcc
     2881 gccgccagca gttggagaca gatcaggttg ctactgcgat gaacgaaatg tcagctactg
     2941 tgcaggatgt ggctgggaac gcggccagtg cagcaagagc agcacaggaa gcagatcagc
     3001 agtcggaaag tggaaagctt gttgttcatc aaacaatctc ttctatcgac agcctagcca
     3061 gtgaagttga gcacgcggcc accgttatcc atgagcttga agcagacagt gctggtatta
     3121 gctctgtggt ggatgtcatt cgcagcatcg ccgatcaaac caatttactt gcccttaatg
     3181 cggctattga agctgcaaga gctggtgagc aagggcgagg ctttgctgtg gtggcggatg
     3241 aggtgcgctc gcttgcttcg cgcacgcaac agtcaaccag cgaaattcag accatgattg
     3301 aaaaactgca gggcggggca aatcgtgctg ttgcggtcat gcaaagtagt tgcaccaaag
     3361 cacaagctgg taaacaacag gttgccagcg caggtcatat gctggatcag atcagtaacg
     3421 ctgttgcgat tattaatgac atgaatgcca tgattgcatc tgccgctgag gagcaaagct
     3481 ctgtcgcgga ggagatcaat cgtaacgtta ctagtgtcag ccagattgcc gaggaaacta
     3541 gcgaggcttc ccgtcagaat gttgccacca gtaagcaact atctgctctg gcaacccaac
     3601 ttcagcgtct ggtgcatatg ttccgtcttt aggcaaactg acgcaggatt gtagtctcgt
     3661 acagcgcctc ctccatcgcc gggtcgctgt agccgaacca gttctgcatc aaatgcacgc
     3721 acaacatcgc catcagcgga taggctggac tgccgccttc acccttcggg tagtgcggct
     3781 cgatcaaggc gatcaaaccc ttccacggca ccacctgatc catctcgatc aggaacaact
     3841 ctttgcgggc ctgcttgcgc ttgccggcat actcggcgta ggcgaaggtc atctgcttca
     3901 tcggaaaact cggcgggtgg aatccgggta ttttgccaaa atcaggaagt cttcttcaga
     3961 gtttccttag cgtacgtttt tctccgaatt ctgcggggtc cccttttgtg ggggctattc
     4021 catccacaag tcgtcgaggt tcttgaagtt ccagagcgtc gggtcttcgg ggccagtgat
     4081 actgtccttg caactcgtgg ccgccaggtc gatggtctgc atcgggatcg gctctctcga
     4141 gcgtagcgag aagaacacgc gaaccttggg agtcagcagt gattccattc ccggctcaac
     4201 gacaacggcc agacgctgag aggacaggcg aaccaaggag ccgacggggt agatgcccac
     4261 ggccttgacg aaggcgtgga agatgcgttt gtcgaaatgg ccctcccact tggccatctg
     4321 ccgcatcgcc gcggacgggt cccacggctt tttgtaggct cgctccgacg tcacggcatc
     4381 atagacgtcg cagattgcgc ccatgcgggc caggagtgaa atggcgtcac cggccaagcg
     4441 atccgggtag ccggttccgt cgatcttctc gtgatggtgc agggcaatgt ccaccacccc
     4501 gggctcggcc ccgcctgcgc gcagcatctt tgcgccctcc acagggtggc gcttcatgat
     4561 ggcgaactcg gcatcggtga gcttgcctgg tttgttaagc acttccagcg gcatcgcggc
     4621 cttgcctagg tcgtgcatca gtccgccgat gccagccagg cgcgtttgct cctcgtctag
     4681 atcgagatgc cgggccagcg atagcatcag ggcgcagacg gcaaccgagt gcaggtaggt
     4741 gtaatcgtcg tgcgttttga tgcgtgcgac gctgatgagg gcatgaggtt ggcgcagcac
     4801 cgaggcagcg atttctccga ccagcggcaa cgtcgtgctt gggtcgacgg ccttgccaag
     4861 ccgggcttcc tggaacatgt ccatgacttg gaacttggcc gcaagacaga gtttccgtgc
     4921 ataacacatt tcgctctcca ttgaggttgc gccgtcactt ttcttgctta gtggactaga
     4981 cggcagagat tgctcctccg acaattctct gggctctggg ctctgggctc tgggctctct
     5041 gggctctctg ggctctctgg gtcgacttgg cttttggcca agtcgaccca gacctccccg
     5101 acgccacatt ctcgaatggc agagagatcc tgaggctcgg tcagcaggaa gctgccgcgc
     5161 cagaatgggt gtcgaaacca agagccggcg agcttgtgga tgtacatgcc gagacgaagc
     5221 tcggatacgg gaatgcgttt taccaactta ttttcctttc tgagttgggt ggttaggcgt
     5281 gcgccgaggc tggcacccag cggtagagcg gaggtaaggt cacgccaaga ttcttggatc
     5341 agccggaacc gccgaaattg ggattccggc gtacaacccc taacaggggc atcaacaatg
     5401 aagtggggcc cactgacccc actcaatcac cgtactccct gtcaccatac tctcgatact
     5461 cccgcccgag gctcatagag ctacgccgcg gctccagctc aatgttcagg gcttcaattt
     5521 ttggctcaat gtctcgactt gaccgctcaa gtgcaacacc tgcttgctca agctccccac
     5581 gctctctcgc aatgcccggt tctcggtaga ggtggcctcg aacatctgcc gcaaatcgct
     5641 gtaggcgctc tcccaggccg cgtgctgcgc tctgtacccg ccttccaagc tctctaacgc
     5701 tttcaataac tgccgctcta gttccgtcat tcagtacccc tccgggatcc tccagggata
     5761 ttcccctctc tctgattcct cttcgcggcc ataggccaac tccttcaagt ccatcttcac
     5821 gcacagccgc tggtccttgc cgcacgtcga cagttccaat tttccgccct tcgctgccaa
     5881 ctgctccaat gtcttgttct ggcgtgagat ctctacccag ttctcggcga tgaccctgcc
     5941 ctggtaccac accacgaccc agctgatccc cagcagaaac gccaccccga tcaacggaaa
     6001 gacccacccc ttcaacacca gccagcccca cctccggttc tgggcgtcga tagcggtgtt
     6061 caatctccgc gcgcttgatt ccaacgccgc gagaatagct ctctcgtgcg gctcgaacgc
     6121 gttcttcacg ctcgtttcga tatcgctcgc ctgctgcttc gagctctctt cgaaggtctt
     6181 ggccagctct aaaatcttgc tcatacaggg ccccttttag ccggatattc cgcccccctt
     6241 ccgggtcggc aatgctgata ctcttgcggg tctcccgcac cacctcaaag ccgtgttgct
     6301 tcaacgtggc caccacgtct ccccggtcgg ccagctcacc ggccgccgcc agtgaaagca
     6361 gaccgtcggt gatcgcttgt gccgcgtcct gtttggcttt tggcaagttg ctgggggtca
     6421 tcaatgcccg tttgttcaag ggatcatccg ggtcatgcaa gcccaactgg gcgttgacca
     6481 ccaccttcca cgcatcgatg cggggccggt cggcccggtc gaaatagggt tgcagccgct
     6541 tgccactcag cagttcgata ttcgggatca cgaagttgag ctcaagccgt tctttgtccc
     6601 ggtgctccac ccacaggcag gcgtactgat cccgatccag ccccggcaat aacgcacgct
     6661 cgaagctgtc catcagcttg tccttgtcct ccctgggcaa atccgcttcc tggaacgaca
     6721 gcacgccaga ggtgtacttt ttggcgtagg ggctgctgtc gatcagcgcc tcgatgagac
     6781 ccggatcgcc acggtcaagg gtcgccccct cccgatcccg ctgcggcccc agcaggtaat
     6841 cgaccgggcc gctaccgcgc cccacaccac gggcatgaaa tttgacgatc atgactcgct
     6901 gcacagccag acggtggcca cactgagcgc ttcatcgtgc tcctggtaaa cctccccgct
     6961 gacctcctgg ccgtccttca acaaccgcaa gctccacccc tgttcgccgg gcaaccggat
     7021 cagggtgtag tcatactcgg ctacgccgta ttcgttcatc acgttacctc cgttgagggg
     7081 acagacaggg cctgcaaagc acgctccatc gccatcagca cagcgatcac ctggacacgt
     7141 tcaaccgcac cccactcccc gctattcact cgccgcgcta cctggttgag gttgttgccg
     7201 atcccggcta tctgcctcag cagagccgga tcggctttgg gtaccggtgt ccgccgtcga
     7261 gcggcggcct tgtcgtgccc aagacactgg ctccgcatcc attcggccag ccgttcatcg
     7321 ccactcaagc ccttgagccg ggcaaattcc tcgtcggtga ctcggatctt gatcacccgt
     7381 tcacgtttgg ccggggtcat ttctggtcac cgttaccgga atgaagctgc cccagccacg
     7441 ccgaccgcac agcatcatgc aaccgggcca ccacctcggg ggccaaggtc gaggttcggc
     7501 catcccgtag gttcagcagg aagatctcca gctcgccaca atccggacga tttaaggtaa
     7561 cggtgaccgt tttttcccgt tgccgtgccc ggtaagcagc ttgcttggcg gcagggctca
     7621 acgccttgcc ggtaggtggc cgaccccggc gcttgccact cggcaacaag tccagcgtct
     7681 ggtcgtctcg tgcatccttc atccgatcac ctcaattacg gtaactgtga ccatatacct
     7741 atcctgtccg ccgacctggg aaagcccgga acggggtttt tcggggcggt ggaggcaggg
     7801 ggtttcgggg gcggcacgcc cctgaaccag cttcacagag gaaccgaaga cgcgaagcgg
     7861 ctaagggccc tctgtgtatg ctggcttaga gtcaagtttg acatagccgg aataggttgt
     7921 aaccacctgt tggcgagact agttaaagta acagtgacta taattagagg gcttcgaggg
     7981 taggtaaccg gtaggaggca aaaagagctc aacgaggggg tgatgatacg tgccctgggg
     8041 aaacaaaaaa cgggagaaaa ggatgttggc aagccgccac agtttgccgg gctctcctat
     8101 ctttcgctgc gcttcaagat aggagagccc tcctacagac ccatatcgat ttgaggtctt
     8161 ttacaggata agctcgcctt gctccggact atcgagactg cttgcggcag ctccctctca
     8221 cgcgctccag agaacacacc ccgtcccgct gcactctgct ttagcccccg cctgttggtc
     8281 gggctgccgc gccgtttttt aagagctggc cgtggttggt tccccgttac gctctacttg
     8341 cagatgcccc agggttgcga gtcctgggag gctgtggtgc gcgattgcac gcttgggcag
     8401 tatgtgagat ttc
//
