LOCUS       NZ_CP086523            34058 bp    DNA     circular CON 28-MAY-2024
DEFINITION  Escherichia coli strain Ec-042-T20-ESBL plasmid pEc-042-T20-ESBL_3,
            complete sequence.
ACCESSION   NZ_CP086523
VERSION     NZ_CP086523.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN22108720
            Assembly: GCF_022759885.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 34058)
  AUTHORS   Moser,A.I., Endimiani,A., Campos-Madueno,E.I. and Vallone,A.
  TITLE     Genome plasticity in E. coli and K. pneumoniae: SNV accumulation
            over time
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 34058)
  AUTHORS   Moser,A.I., Endimiani,A., Campos-Madueno,E.I. and Vallone,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-NOV-2021) Institute for Infectious Diseases,
            University of Bern, Friedbuehlstrasse 51, Bern 3001, Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 273x
            Sequencing Technology :: Illumina NovaSeq; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022759885.1-RS_2024_05_28
            Annotation Date                   :: 05/28/2024 04:43:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,717
            CDSs (total)                      :: 4,596
            Genes (coding)                    :: 4,365
            CDSs (with protein)               :: 4,365
            Genes (RNA)                       :: 121
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 231
            CDSs (without protein)            :: 231
            Pseudo Genes (ambiguous residues) :: 0 of 231
            Pseudo Genes (frameshifted)       :: 63 of 231
            Pseudo Genes (incomplete)         :: 155 of 231
            Pseudo Genes (internal stop)      :: 41 of 231
            Pseudo Genes (multiple problems)  :: 25 of 231
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP086523.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..34058
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="Ec-042-T20-ESBL"
                     /isolation_source="stool"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pEc-042-T20-ESBL_3"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019"
                     /collected_by="Institute for Infectious Diseases Bern"
     gene            complement(join(33326..34058,1..362))
                     /locus_tag="LNN45_RS23215"
                     /old_locus_tag="LNN45_23210"
     CDS             complement(join(33326..34058,1..362))
                     /locus_tag="LNN45_RS23215"
                     /old_locus_tag="LNN45_23210"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /GO_process="GO:0030255 - protein secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000046889.1"
                     /translation="MAQGFFVKYNSTVMDSVDKISSSYQTQFANDIMSLATVSVTLYVL
                     WKGYQILASKTQTPLQDLVWDLSKFAIIIMFITNADGYLTAATDALQGMKDGFSGGVSV
                     WQTLDNLWKSTQNLGAEIYSLDKSTYVKDQGVVGQFLIWTGSLILMAVSVVVFLTADVT
                     MKLLIITAPIFIFCLMFGFIRSMFNNWLQSLFSSILTVLFASLVIRIAMDFQGMILSHA
                     IRAAQTGNVNLVSTGAMGFMAGFLGALLVLIAKGFAVQLAGAGVEGAVQGAAMMGLGAA
                     GMATGKSLMLGGRAGLGFGLGMAGRTGMNSLSGKAGNLMGRGARTAAEWAGEKGYQALA
                     PTGALGMKARRLASLEKARARNAA"
                     /name="type IV secretion system protein"
     gene            complement(374..1090)
                     /locus_tag="LNN45_RS23220"
                     /old_locus_tag="LNN45_23215"
     CDS             complement(374..1090)
                     /locus_tag="LNN45_RS23220"
                     /old_locus_tag="LNN45_23215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000832280.1"
                     /translation="MKRVKTFMLISLLTASFYSSAGIPVAIDASPEWAVEAARWTERLK
                     QWSETAQHYQSQIQAYKDQLATATGIRNIAAFTNELSNLQSELTNIYKQGNSYISDFTS
                     NPEGALSSQAKNLFSKYGAFDMCNTGYERNDNLCKARIVSTAASIEQGNEINKQLSNAM
                     SQIQSLSSRIEASKDIKESQDLANALQAQSLKMQAIKMQYDVWNNKNKADHEMLITQEQ
                     EAFIKQQKEAEPLTFD"
                     /name="type IV secretion system protein"
     gene            complement(1102..3849)
                     /locus_tag="LNN45_RS23225"
                     /old_locus_tag="LNN45_23220"
     CDS             complement(1102..3849)
                     /locus_tag="LNN45_RS23225"
                     /old_locus_tag="LNN45_23220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="WP_000105985.1"
                     /translation="MSTLYKAMTRPAMYVGVPVVPLTVVAGALFLAGVYISKLIWLAIP
                     VAVFVLRMITKQDDHIFNLYFLKLKMLGNSVCNRFFGARAFLSGQYEAVEIDEFVNAMK
                     LNERITTGKYIPYSSHVDKNIVKTKNGDYVATWQLMGINFESISAEMLETIDSQVATLV
                     RSFSGLPVSFYNHSCRASFYDAFTTKSGNKYADIISDCYYGSMKKNKFKGNTLYFTLIY
                     RPDGRVEKLEKRKKSIKEKKDDINIHVKRMNEMINTFSGALDKFTCKLLGMYEENGKVF
                     SSQLSFYNYLLTGKLQKIRVTDSPVYNVLGGVDVFFNHDTGQICRIDGNKFFRSIEIKD
                     FCSETASGVFDVLQYSDADYIITHSYTSMSKSEALSTIKRAEKQLKSTEDDAVTQLQEL
                     EKAKNDIVSGDISFGYYHFTLMVMADSIRELDESVSKITADFTDLGIIPALSTMSLPAA
                     YFAQLPAVFHLRPRLSPVSNVNFVELASFHNFYQGKRDKNCWTEAVAILKTPSKQAYYL
                     NLHNSVLFKDETGEKNLANTKVIGTAGSGKTMFLSYLACSLQKYNNPETFADSAKNKKL
                     TCVFLDKDRGAELCIRMLGGEYYTVKSGEPTGWNPFALEATKRNRIFVKQLMEILCTRN
                     GERLSTRERLLISESVDAVMDFPPGEMREYGITRMLEHLMQRDDRDEQENGIILRLSQW
                     ANGQAHGWVFDNAKDTFNIQHVNNFGIDGTEFLDDPMVCAPITFYLLYRITQLLDGRRL
                     VIFLDEFWKWLQDEAFSDFVYNKLKTIRKLNGLVIPATQSPDEILKNKISRAVVEVCST
                     SIYLANPDADYNDYVEGLKLTPEEFNIVKNLDPMSRQFLIKKSSLKKGDGKSFSALATL
                     DLSGLGGYLKILSASADNLEIFESIYHEGMEPDDWVPEYLERAI"
                     /name="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
     gene            complement(3868..4194)
                     /locus_tag="LNN45_RS23230"
                     /old_locus_tag="LNN45_23225"
     CDS             complement(3868..4194)
                     /locus_tag="LNN45_RS23230"
                     /old_locus_tag="LNN45_23225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000008647.1"
                     /translation="MSFKKSVCNRISSSVTAVMQRKNKVVMAVAGATVASPAFADGFSK
                     AETLLEKVKTGLSGLSLVTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAEVAS
                     MMVN"
                     /name="TrbC/VirB2 family protein"
     gene            complement(4208..4828)
                     /locus_tag="LNN45_RS23235"
                     /old_locus_tag="LNN45_23230"
     CDS             complement(4208..4828)
                     /locus_tag="LNN45_RS23235"
                     /old_locus_tag="LNN45_23230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_001299949.1"
                     /translation="MASLFPALLLCAASVHPDTINDIARVESGFNPYAVAEIIPERERG
                     SYGKSVISHMPKSKEEALTVIREIENRKRRYSVGLMQITNSNFSFYSTSAEKLLDPCEN
                     LSVFEKIIVDCYKRGRSLENALSCYYTGNFSNGKRKEKEFNNTSYVERIGYTGNEKKYV
                     VPGTRSNGGEQRKNRSHNASVIWPETILKSAFVDNSHPTKVIN"
                     /name="lytic transglycosylase domain-containing protein"
     gene            complement(4831..5007)
                     /locus_tag="LNN45_RS23240"
                     /old_locus_tag="LNN45_23235"
     CDS             complement(4831..5007)
                     /locus_tag="LNN45_RS23240"
                     /old_locus_tag="LNN45_23235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000660496.1"
                     /translation="MKEKPDKSSEKGVYVTIKLDPRLNAFIEEKTKTSLLSKRKQIIYL
                     LMQSMRIDGYMER"
                     /name="hypothetical protein"
     gene            complement(5184..5399)
                     /locus_tag="LNN45_RS23245"
                     /old_locus_tag="LNN45_23240"
     CDS             complement(5184..5399)
                     /locus_tag="LNN45_RS23245"
                     /old_locus_tag="LNN45_23240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000760375.1"
                     /translation="MKKYLLFALPFFVVGCSEEVKSVDWWGQHLTEAKQKQAECEKSGS
                     DSQNCKNVKQALFIQSQKDAPVPTFD"
                     /name="EexN family lipoprotein"
     gene            complement(5396..5689)
                     /locus_tag="LNN45_RS23250"
                     /old_locus_tag="LNN45_23245"
     CDS             complement(5396..5689)
                     /locus_tag="LNN45_RS23250"
                     /old_locus_tag="LNN45_23245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134733.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO:0016987 - sigma factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_000134733.1"
                     /translation="MTEHDAICISALHQIFSDEEHLSEQQKDIILMYAYGYTLNEIADF
                     KGLKPSTVRKYLDSVRAELGGVSLAGIRTLVLIRTNALLVSSLSRISERGNL"
                     /name="sigma factor-like helix-turn-helix DNA-binding
                     protein"
     gene            complement(5766..6995)
                     /gene="taxC"
                     /locus_tag="LNN45_RS23255"
                     /old_locus_tag="LNN45_23250"
     CDS             complement(5766..6995)
                     /gene="taxC"
                     /locus_tag="LNN45_RS23255"
                     /old_locus_tag="LNN45_23250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA relaxase/nickase TaxC"
                     /protein_id="WP_058815700.1"
                     /translation="MGVYVEQEYRIKRAKGTGRDPKSPKLSGRHIHASKSAFNHKVRHG
                     TDKKAYTWTPTKEVTFKITGSGKTAAGIKNGIDYITRNGELEAYCYDGKGSEQTGKGED
                     FNREFTSTLSKGNDYSRTYRGENIDHVKNMVFSPPPEAGVSREDALKATIEFLKETYPN
                     HAFVAVYHDDKEDHPHVHVNIKLRDEETGRRLRLTKSETRKFRNGFHRKLKGMGYDVTA
                     TWKKDPERKREIERLQAENPKRLRNVYKVVDFGETSYQNKAGEKRTPFLTYETLKGGKQ
                     VTIWGKDLKNHFESEKLQAGTLIKVKKLAPTLVRSPMFNDDGTVAGYRETHRNNWQIEN
                     IALERNRERQVHERETRQPEESDVKKQLSRKHEQGHNIGFALEHGFTKDSEEHKKLRIQ
                     QERNWKGLGF"
                     /name="taxC"
     gene            complement(6999..7502)
                     /gene="ddp1"
                     /locus_tag="LNN45_RS23260"
                     /old_locus_tag="LNN45_23255"
     CDS             complement(6999..7502)
                     /gene="ddp1"
                     /locus_tag="LNN45_RS23260"
                     /old_locus_tag="LNN45_23255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 1"
                     /protein_id="WP_000781818.1"
                     /translation="MKMIAFRLSDDELKLAEHNAISSGFTSINTFARHNVLNVDVQPSN
                     IPVSNESSKAVKTCLYPHEIELVKRNAALHGMSMSREIAIRVRQSLLKNEVCLYPDEVK
                     ELKKLSTAVDRVGRNIHFIIKGERFCTVNDPDFRKDVVEVIELCKQIDSKLETLTKSVV
                     NRFG"
                     /name="ddp1"
     gene            complement(7865..>8062)
                     /locus_tag="LNN45_RS23265"
                     /old_locus_tag="LNN45_23260"
                     /pseudo=""
     CDS             complement(7865..>8062)
                     /locus_tag="LNN45_RS23265"
                     /old_locus_tag="LNN45_23260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681609.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /name="type II toxin-antitoxin system HicB family
                     antitoxin"
     gene            complement(8313..8678)
                     /locus_tag="LNN45_RS23270"
                     /old_locus_tag="LNN45_23265"
     CDS             complement(8313..8678)
                     /locus_tag="LNN45_RS23270"
                     /old_locus_tag="LNN45_23265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000854262.1"
                     /translation="MKTLKQAAMQFASDLRNNRCFKAAYNDALLELDREDLNAIVQCTF
                     LFEPKRTLAELDKLIKKIEVEEDYEFCVSLDKGNGLHEVRTFKSEREALDAYRILTLYG
                     YTVTIEKKEGNDWLFKV"
                     /name="hypothetical protein"
     gene            complement(8770..9069)
                     /locus_tag="LNN45_RS23275"
                     /old_locus_tag="LNN45_23270"
     CDS             complement(8770..9069)
                     /locus_tag="LNN45_RS23275"
                     /old_locus_tag="LNN45_23270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000650313.1"
                     /translation="MKCSSVFTSTTNHVFTFERVTLCTIILMHKDTGQQYVVLFTDNNK
                     IRDYKTGIVPQFGELKQSDVDLVLFYRDEYEKYFDSLKDGDECLSFKDFIECLR"
                     /name="hypothetical protein"
     gene            complement(9461..9688)
                     /locus_tag="LNN45_RS23280"
                     /old_locus_tag="LNN45_23275"
     CDS             complement(9461..9688)
                     /locus_tag="LNN45_RS23280"
                     /old_locus_tag="LNN45_23275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000801440.1"
                     /translation="MKPDNTPENVKKLRLKAGLTQKECSHIYGVGLRTWQKKEEVNTQN
                     SQSLSLVEFEFLLLLAGEHPEYVLCKRESK"
                     /name="hypothetical protein"
     gene            complement(9675..9926)
                     /locus_tag="LNN45_RS23285"
                     /old_locus_tag="LNN45_23280"
     CDS             complement(9675..9926)
                     /locus_tag="LNN45_RS23285"
                     /old_locus_tag="LNN45_23280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001565860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001230708.1"
                     /translation="MRKNKGDVTYFLEKEGDNYRLTKRIKARTNVKIGNKTTKITLYDA
                     VLNENELQHIDFTCAGLRKDDETPVKNLIKEFMLNETR"
                     /name="hypothetical protein"
     gene            complement(9923..10465)
                     /locus_tag="LNN45_RS23290"
                     /old_locus_tag="LNN45_23285"
     CDS             complement(9923..10465)
                     /locus_tag="LNN45_RS23290"
                     /old_locus_tag="LNN45_23285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001083908.1"
                     /translation="MNSFFEQYHPVFEVVCRILGNGWRVNKLDDCSSRIKLTSPQFKNY
                     SVHIRMEKDRFSVVGSVDSRSWRSPHHVCTLSRKRNPVDIAADIERKILVNASQEVLQA
                     IEYEKHQVEKKDEIMILKGMLSQLVQLESWYGALTGFKAENGLNGKVTEQGDSYDLQIR
                     GLSIDQLVKITGYLKQL"
                     /name="hypothetical protein"
     gene            complement(10570..11085)
                     /locus_tag="LNN45_RS23295"
                     /old_locus_tag="LNN45_23290"
     CDS             complement(10570..11085)
                     /locus_tag="LNN45_RS23295"
                     /old_locus_tag="LNN45_23290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025396.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025396.1"
                     /translation="MNIQEALNVFGLSGELTEKDIKAAYRKAALKYHPDRNPLGAELMK
                     AVNAAFDVLMANIDKINQFQSTDEHARYNYGDDLEKVLNVLSGLSGLVFEVIGNWVWIS
                     GETITHKETLKEIGCKWAAKKKQWFYRPDEHKSYWNREEHTIEEIRAKYGTTGQRRATG
                     WQRVETRV"
                     /name="J domain-containing protein"
     gene            complement(11724..12074)
                     /locus_tag="LNN45_RS23300"
                     /old_locus_tag="LNN45_23295"
     CDS             complement(11724..12074)
                     /locus_tag="LNN45_RS23300"
                     /old_locus_tag="LNN45_23295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000127483.1"
                     /translation="MTATKNVKSQKNDYSASVDHNAAMIEELRADPDYANAYLANALEE
                     INEPGGLGGFLVALRQVIEARGGISEAARKSGLARQSIYRALSPNGNPTITTLAQLTSV
                     AGLQFTLSKSSH"
                     /name="hypothetical protein"
     gene            complement(12071..12406)
                     /locus_tag="LNN45_RS23305"
                     /old_locus_tag="LNN45_23300"
     CDS             complement(12071..12406)
                     /locus_tag="LNN45_RS23305"
                     /old_locus_tag="LNN45_23300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004026069.1"
                     /GO_function="GO:0004540 - RNA nuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0008219 - cell death [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001147119.1"
                     /translation="MPYTAKRYQTENGEVPYTDWMKKLRRKDQTAALKVDSRIARAMGG
                     NFGDHKFERDGVWELRVDYGPGYRVYYSIEDGEIILLLIGGNKKTQTADLDKAVSYLQD
                     FKKRSKK"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            13950..14957
                     /locus_tag="LNN45_RS23310"
                     /old_locus_tag="LNN45_23305"
     CDS             13950..14957
                     /locus_tag="LNN45_RS23310"
                     /old_locus_tag="LNN45_23305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243325.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000243324.1"
                     /translation="MVLKNNKNSDCNDVQSLLAQGNQLLEGAYDITLIEMRLLYLALTK
                     IDSRKPQPANEYTLFAKEYRDTFSLDSKNCYEQLKSAASSLGSKPIVTYEWNEAKKRID
                     AVKRFWFSSIRYGVGNSESDITLRFSDSVSQYLYELKSEFTQMNLEHMVKLDTPFSFRL
                     YSWLYKYKNLNRNKKHSGVISTDPITIEWMKERTGLTGKYPVYKDFKKRVLDPAVDIIN
                     ANTNLSVTYEGIKSGRKIESVVFTYLVENETHDGKKIATKPLRPRLPSRPRVIKGSSAE
                     VAWAKKCIDVMKNYLISLREYDDKLKLSRPDLQKVKLWHEITGWDFEESFWFSD"
                     /name="replication initiation protein"
     gene            15023..15427
                     /locus_tag="LNN45_RS23315"
                     /old_locus_tag="LNN45_23310"
     CDS             15023..15427
                     /locus_tag="LNN45_RS23315"
                     /old_locus_tag="LNN45_23310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000654313.1"
                     /translation="MKDNIVDFQRIRRDLGAHSTDVANDAVYSDKKKTSRFFYLLTPVR
                     YLLAASLYLVVVIPLGILAGFRFLLQFLGGIAVMGLTIAWYMGADVSGYIVLAAWIALT
                     VCGCAEQIFEWWIESRFAFRLFGIGRTPEE"
                     /name="hypothetical protein"
     gene            15563..16090
                     /locus_tag="LNN45_RS23320"
                     /old_locus_tag="LNN45_23315"
     CDS             15563..16090
                     /locus_tag="LNN45_RS23320"
                     /old_locus_tag="LNN45_23315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="WP_000577047.1"
                     /translation="MIFNRNKKRDEQQNSSVVLPSTENVFSDFIKNNPALTTNAFTAIG
                     EVDCFTKVPLLSNKESEFLGILSRNIIPDYSVFPKIRLIEFVRPHGSEEAVKELIREVQ
                     NITCDFVLKSYDETVLAVIQFGETATVRQQKKKLIIQRVCAMTEISFFEFKNTVDMMGS
                     EDFCQFLRDDEE"
                     /name="DUF2726 domain-containing protein"
     gene            complement(16397..16612)
                     /locus_tag="LNN45_RS23630"
     CDS             complement(16397..16612)
                     /locus_tag="LNN45_RS23630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000399458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000399460.1"
                     /translation="MEHCIFDLGIINYHPVITWTVPVAFFFLVLLAGIVFNIGRKSNLI
                     VFILAMLLPVTTVFIFMLLGGKIDMC"
                     /name="hypothetical protein"
     gene            complement(16662..16913)
                     /locus_tag="LNN45_RS23325"
                     /old_locus_tag="LNN45_23320"
     CDS             complement(16662..16913)
                     /locus_tag="LNN45_RS23325"
                     /old_locus_tag="LNN45_23320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001482241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000905709.1"
                     /translation="MLIKIIKSVFNFYMLCVQPFIGLVLAGYGAWKFSGDSISALLEPA
                     SYFVIGTVVLFVWYIAWQKERSKEEEFKSSIKPEDFVK"
                     /name="hypothetical protein"
     gene            complement(16950..17252)
                     /locus_tag="LNN45_RS23330"
                     /old_locus_tag="LNN45_23325"
     CDS             complement(16950..17252)
                     /locus_tag="LNN45_RS23330"
                     /old_locus_tag="LNN45_23325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001062964.1"
                     /translation="MAKIPKKIDQEIKPLDLRQFVSSAAQKPASASAVTRINLTMTDDD
                     LDTAQVFQNKYGASRAEVIRAALAALRLVSAEERRRLFDDIRKNSPKAGRPTVNK"
                     /name="hypothetical protein"
     gene            complement(17418..18077)
                     /locus_tag="LNN45_RS23335"
                     /old_locus_tag="LNN45_23330"
     CDS             complement(17418..18077)
                     /locus_tag="LNN45_RS23335"
                     /old_locus_tag="LNN45_23330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000516230.1"
                     /translation="MGKIITVAGHKGGIGKSTVLCSLCVCVIKKGKTACFLETDSQGSI
                     KDFIEDRKTNARLSEIPYFECYTDIPAMAQKLAARFDYVFVDTPGMKSPAFVKALSCAH
                     ILFTFIEPGSGIEINTLGRLVFDIKTAQAGVNPSMKAWIVLNKCSTNPSDSEASELRRQ
                     LNDDPDWLPVPRQRIYMRTAHKKAYNNGMGVHEYDDKRGNKARGEIELLLKETDIL"
                     /name="division plane positioning ATPase MipZ"
     gene            complement(18182..19006)
                     /locus_tag="LNN45_RS23340"
                     /old_locus_tag="LNN45_23335"
     CDS             complement(18182..19006)
                     /locus_tag="LNN45_RS23340"
                     /old_locus_tag="LNN45_23335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001487124.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA];
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_016238959.1"
                     /translation="MSDLPASIFQISRSDAWNLTISPDAARNMRDLASQIGAGMPKYLI
                     APEVSLLLSYIDDLNIRMYFETLWNTGARLNEALALKPADFMLTPTRQYPQPVVILKTL
                     KQRLKEAERRPGRPTTRHPPLHPDPRYRKPPEPAVRLVPVLDAGYALRMREYLATWKKR
                     IKHQPVWDITSRQTPLNWINTAVARAERDGVTFSVPVTPHTFRHSYAMHLTMSGVPPRV
                     LQSLLGHRYARSTEIYTRVFSLDVLTGSGLSFTCDPQLAKQLLGYPERLNNE"
                     /name="tyrosine-type recombinase/integrase"
     gene            complement(19091..19480)
                     /locus_tag="LNN45_RS23345"
                     /old_locus_tag="LNN45_23340"
     CDS             complement(19091..19480)
                     /locus_tag="LNN45_RS23345"
                     /old_locus_tag="LNN45_23340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_223196981.1"
                     /translation="MTLSKILTDIFRTANNLTHCKTTNQLLAGDASSTLASAILSCDRY
                     SIFEQDYPRSGLIRQAVRHTGHSVQTSLVTTFKYSVPLSGALFRHMCPYPGLFRITASF
                     SPCPVVHIHLDKNALSEKMSKFFFW"
                     /name="hypothetical protein"
     gene            complement(19563..20219)
                     /locus_tag="LNN45_RS23350"
                     /old_locus_tag="LNN45_23345"
     CDS             complement(19563..20219)
                     /locus_tag="LNN45_RS23350"
                     /old_locus_tag="LNN45_23345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001478769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000972911.1"
                     /translation="MMIKSKKVVVIFVALSSFLLAGCDSPKDANKQNFEKAINTRLEKE
                     CITISPLGMFDSKPYPVQIAVAQANRYTSQERADEINSRQFSALDVLVKADLLTVKNTL
                     VDDVIGFTKTGKKVPGREYALTDEGKKYLKSPERPDFCVGHYKVDEIVDFTEPGDAMGM
                     KITQVNYTFSPTSIAEWAKRDDVRAAFLGLESDLKEKQTKHITLVLKNDGWSAER"
                     /name="hypothetical protein"
     gene            complement(20323..20787)
                     /locus_tag="LNN45_RS23355"
                     /old_locus_tag="LNN45_23350"
     CDS             complement(20323..20787)
                     /locus_tag="LNN45_RS23355"
                     /old_locus_tag="LNN45_23350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293133.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0030527 - structural constituent of chromatin [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_001293133.1"
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFAREIDFEQLLEMQEKLNVV
                     IEERREDAEREAAERQELEAKRQQAIEYIISLGLDPESLLAPVTADTVKTRRKAKGGVR
                     KAKYRFKDENGEIREWSGNGKRPLALQKLLDEGHFMEDFLIDKLQPGQVE"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            complement(20803..21009)
                     /gene="hha"
                     /locus_tag="LNN45_RS23360"
                     /old_locus_tag="LNN45_23355"
     CDS             complement(20803..21009)
                     /gene="hha"
                     /locus_tag="LNN45_RS23360"
                     /old_locus_tag="LNN45_23355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_000850859.1"
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
                     /name="hha"
     gene            complement(21006..23159)
                     /locus_tag="LNN45_RS23365"
                     /old_locus_tag="LNN45_23360"
     CDS             complement(21006..23159)
                     /locus_tag="LNN45_RS23365"
                     /old_locus_tag="LNN45_23360"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_001235747.1"
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPEYKAWKVETLPLRLYPVKYQPVESAAKQVKTILELIRRGDVTEIVHAGD
                     PDDEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKALARS
                     VADAVYGFSMTRAYTIPAKARGYQGVLSVGRVQTPVLGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVIRANWKPGEFAPLTDRKLLDKAWADGTAASLAGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKMTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFPQSLDIDSARKSKAFNSAKVTAHTAIIPTASVPDVNALSTDERNVYLAIAQ
                     HYLVQFMPEKAYQEVSVAIQCGDESFYARARKTTDSGFEAFLGAETTDEGESEDNDDSA
                     FELLCKIRTGETLTTKEVVVNEKKTTPPPLFTEASLLAALVRVADFVTDPTIKKLLKDK
                     DKDKKDEHGGIGTPATRAAILETLKKRNYITLEKGKLIPTDTGYALIDALPGIAVNPDM
                     TALWSEKQTAIENGDLTVEEFINELYGELTGMISDVDLGEMKIEPAAPAGQFQRLDSPC
                     PSCGKHIVIRPKGYFCTGCEFKIWSEFSGKKITQAQAEKLVKSGKTDLIKGFKKKSGGT
                     YDTVLVLEDKKTGKLGFPVRAKK"
                     /name="type IA DNA topoisomerase"
     gene            complement(23164..23736)
                     /locus_tag="LNN45_RS23370"
                     /old_locus_tag="LNN45_23365"
     CDS             complement(23164..23736)
                     /locus_tag="LNN45_RS23370"
                     /old_locus_tag="LNN45_23365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001199073.1"
                     /translation="MQYALVDALERKFLLDALEFGVLKDWKENPVKELPDIDESVHPFH
                     ICYGGYLLNPGVSDSDISRKIKDQAGFWLAAIDDTRMDCHSIAYYDIHTLPLISCGHQK
                     IVPFAALIKADECIISKIASYSGFAVTAFLRIKEWDIATNILNREGIFAFNGCERRFRV
                     VSKDNWQHTVSEERAIRCAKRLIQCKG"
                     /name="hypothetical protein"
     gene            complement(23740..25002)
                     /locus_tag="LNN45_RS23375"
                     /old_locus_tag="LNN45_23370"
     CDS             complement(23740..25002)
                     /locus_tag="LNN45_RS23375"
                     /old_locus_tag="LNN45_23370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517490.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000517489.1"
                     /translation="MGKLTLVEQALRLHKEYYGEDNFGTVVKDCDYYPKVAEIFINRKN
                     RKIYSNLDIEPVASTVVHTGSNPVMAKAGRIKKLMFKDGSGAYRIHLGQNEVVHIIRFI
                     LNSKVRMEYAVGTTKSMSMLHNLCEAGRAKLNRSLPRKGIWKLGYYDGVYYHGKARKEE
                     IENAMRFSVHPKFDELENDFNQFFSDIDFYTRYGQSGMRKVLFTGPPGTGKTTIAKALG
                     AKYQDKYVFVYADDYFKDVCYAAAQKKIPVIIIAEEVDELYRADAGTLSFLDGADTPRN
                     VAGTYVIFSTNYPKRIDPRIRKRPGRIDRIISVGAFRTKAAAACAKMYLPEDVEIDLKE
                     LGAVLDRTTPAEIKEIINIAIGMIRGTKNELSVDVIKNARAFLKGTLDLSVQEADEDIE
                     EREELYKKNGAQPDYLSYLED"
                     /name="AAA family ATPase"
     gene            complement(25084..25578)
                     /locus_tag="LNN45_RS23380"
                     /old_locus_tag="LNN45_23375"
     CDS             complement(25084..25578)
                     /locus_tag="LNN45_RS23380"
                     /old_locus_tag="LNN45_23375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="WP_001215681.1"
                     /translation="MRHFLKALSFVVSLLPATLCAAEIQGKVIRVLDGDTIEVKTLPAK
                     IVVYEVPIRVRLINIDAPEKKQAFGHWSANQLKALLAGQSVTVSYTQTDRYGRIIGRVF
                     TTNGTDASRFMVQSGAAWVYERYNTDKSLPALQREAQEQKRGLWADSNPVPPWEWRHKQ
                     N"
                     /name="thermonuclease family protein"
     gene            complement(25575..25883)
                     /locus_tag="LNN45_RS23385"
                     /old_locus_tag="LNN45_23380"
     CDS             complement(25575..25883)
                     /locus_tag="LNN45_RS23385"
                     /old_locus_tag="LNN45_23380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000647577.1"
                     /translation="MKARSVRVAGIEIIDSVKTVAYVFTEALLFMVWFSAIVYGLYRVV
                     IVLWDDPLKPQSLMEFLNFIVELYSYVLPSLAVIAVALIAVLSICKILSAIWEGRKQ"
                     /name="hypothetical protein"
     gene            complement(25975..26409)
                     /locus_tag="LNN45_RS23390"
                     /old_locus_tag="LNN45_23385"
     CDS             complement(25975..26409)
                     /locus_tag="LNN45_RS23390"
                     /old_locus_tag="LNN45_23385"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_242881453.1"
                     /translation="MKVTKSIIAVLLCLSAGSAYADCEYYLTGNKETLNISDCVDGVKG
                     IANSALSNSQNAQNKEKVDFLNAIKTGHSGFIAGNPAHALDDKTMNAIIQNYVATIVPG
                     KIGNCKETSFTKYCSRTIPERISIEEIDEIKFIQNPSEQG"
                     /name="hypothetical protein"
     gene            complement(26510..26815)
                     /locus_tag="LNN45_RS23395"
                     /old_locus_tag="LNN45_23390"
     CDS             complement(26510..26815)
                     /locus_tag="LNN45_RS23395"
                     /old_locus_tag="LNN45_23390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000147044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_000147045.1"
                     /translation="MTGKNRVVLPALLALGLISTNANASDPCASVLCLYGKAVGQGGGS
                     ECRSAEKDFFNILKKKKGSIRWSKTFDARKAFLNQCSTADPAAISKIMSKFGRVKG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            complement(26799..27221)
                     /locus_tag="LNN45_RS23400"
                     /old_locus_tag="LNN45_23395"
     CDS             complement(26799..27221)
                     /locus_tag="LNN45_RS23400"
                     /old_locus_tag="LNN45_23395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_001328552.1"
                     /translation="MMKKLVFLLISILAGCSSPPEPTPVQFEKANEVINPSLPYVPDFH
                     GVIKSDVSGKGWVYEITSLSGVQARTPTFYYALAHADRIVVTTHDAGLWFRIRDLLKME
                     GATAVVEWRNEKSFLPEQGKIVFIKAQNEVKNDWKK"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            complement(27230..29092)
                     /gene="taxB"
                     /locus_tag="LNN45_RS23405"
                     /old_locus_tag="LNN45_23400"
     CDS             complement(27230..29092)
                     /gene="taxB"
                     /locus_tag="LNN45_RS23405"
                     /old_locus_tag="LNN45_23400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxB"
                     /protein_id="WP_000847103.1"
                     /translation="MKTFNKSQSVFIFAVMLVAAWFAGSFIFFVLYFSQIKNLKPLKAV
                     FRSIDAYRMDIFTDSLTLSVVTTDIRVLAFVALGAGFVVSLIIPVAALIKLNEKKDNIF
                     GDARFATTNDIRESNSFTLDGDEKDGIIVGIKDKKIIRYVGAAFSAMGAGTRAGKGAGI
                     VITNLMKYWWSVIILDPKRECFNITSLIRKVILGHEVYKFDPFSPVTHRFNPLYYVSMG
                     TSEGFNQLENLALIIYPYKTDGADAGSYLNKTAGGVFKSYAVALWFMIKNDKAGLKTLD
                     IEPVFSMSKINQLFERAEPEHLLSFMNDIRSELRGKDKTLADIGVAGLKAFIEMEDKTK
                     AQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNARLAEKITNIF
                     FQLAIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQV
                     GSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGSKSKSRSRGG
                     TSRSESESLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYLHEYFFGDFVKVA
                     PELANIFPRKKGKLVMPPQKVFENEIVAKGYLAVKEVPDLDKAA"
                     /name="taxB"
     gene            complement(29079..30107)
                     /gene="virB11"
                     /locus_tag="LNN45_RS23410"
                     /old_locus_tag="LNN45_23405"
     CDS             complement(29079..30107)
                     /gene="virB11"
                     /locus_tag="LNN45_RS23410"
                     /old_locus_tag="LNN45_23405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401678.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_000017224.1"
                     /translation="MSGVIPVSISNKSLDFYKNQVFQSFLDIEGLTEIAVNRPGEIWTE
                     INGDWTFHNNDGVTFDFCKRFSQTLASFRGDEIGDTKPLLSATLESGERVQVVFPPACE
                     RNTISITIRKPSTRQITHKEYVANGFYDYVQSGKKHRTYDDELLDLFRARNIAAFMELA
                     VAAGKTIVFAGATGSGKTTYMKSLIDFIPLNTRLITIEDAEEIKFFIHKNYVHLFYPSE
                     SGSDSGSIITAAKLIKSCLRMKPDRILLAEIKGGDAWDFVKVAGSGHSGSMTSIHAASA
                     KDAIIQMVTKCYQNRECQNLPFDVLRKIIMDSIDIVVHVGRDGVVRHMSDIYYKGAECE
                     NF"
                     /name="virB11"
     gene            complement(30109..31227)
                     /gene="virB10"
                     /locus_tag="LNN45_RS23415"
                     /old_locus_tag="LNN45_23410"
     CDS             complement(30109..31227)
                     /gene="virB10"
                     /locus_tag="LNN45_RS23415"
                     /old_locus_tag="LNN45_23410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_000131271.1"
                     /translation="MTDMKKTDDLVDDANQSKLESKPVHDIGDIRNKNNRMRSGFLFGL
                     MAVLVIGIFALKTYKNYFADDQQKASESTGDTSISQVSKIRTGLGQNFDPVENKAIINP
                     GATGSGNTVSDGHKEVPQEGFRKYLSIPVAGQGGSQTGASGSSRTSQTSEPQEERKESK
                     ENVPGKSGMKVTAINLDPDLYIEENRLIPCALTTRFVSDVAGRISCVFTEDVWSANHHT
                     KLLEQGTKAFGRYQTGTLNHGQGRMFVMWEQLRTPDNKRIDMVNTAAAGPLGEAGIDGW
                     IDSHFWERFGGSLMLSMVQDVAAAAADNAPGKDRNVDYTENSRQAMAEMAKVALENSIN
                     IPPTMYKNQGDIITIMVGEDIDFSDIYELKVK"
                     /name="virB10"
     gene            complement(31220..32128)
                     /gene="virB9"
                     /locus_tag="LNN45_RS23420"
                     /old_locus_tag="LNN45_23415"
     CDS             complement(31220..32128)
                     /gene="virB9"
                     /locus_tag="LNN45_RS23420"
                     /old_locus_tag="LNN45_23415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_001299943.1"
                     /translation="MMKKLFIATCLLLPGLVYSAATPLPSGFDARMQTVSYNGANTTVI
                     RSKTGFLTSVVFDEGEAVISAKAGFPAGWEITTDDNVVYINPRPVVQEQEGDEGEKLKK
                     VFQPTEKEWDTNLFVRTTKRIYSLDLILLSEEKQAQPAYVVQFRYPSEIAKKNAEEVRL
                     AKEKQEKLRQKKLISESFEKADAPKNWDYFMRVNEKYDSRRIAPDFAYDNGIFTFLGFN
                     SGKVFPAPFAVRDGQEQTLAFNVETKGKYKIMVIHNVNDKFVLRYGNSVVGVVNKSFGK
                     VLTDQRNTSSPAVERVEVNND"
                     /name="virB9"
     gene            complement(32125..32811)
                     /locus_tag="LNN45_RS23425"
                     /old_locus_tag="LNN45_23420"
     CDS             complement(32125..32811)
                     /locus_tag="LNN45_RS23425"
                     /old_locus_tag="LNN45_23420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001290765.1"
                     /translation="MSEKIEKKIETAKSFERQLYAENERSKKNAWRVAVAASLLSLCLG
                     AAICVLVPLKEKELAIVAVGEKTGRTELITQVKQEKILQSEALGRYFVNTYITLREGYN
                     YPSLQYDYETVQLYSSNTVKDDYLRLYNSDMAPDKIYHNNGSYVAVEVISNIISDATAP
                     DKLASVRFKKTTRNFTTGQVSVSYWTARVTYRFEPEKSVKSSSRELNPLGFTVTSYQTD
                     REVRGE"
                     /name="type IV secretion system protein"
     Typing          13951..14957
                     /name="IncX4"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.802"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(5770..6995)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.756"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(4..362)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.167"
                     /coverage="99.0"
                     /evalue="8.409999999999999e-61"
     Typing          complement(27234..29092)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.839"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(31224..32128)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(32129..32811)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.4399999999999998e-137"
     Typing          complement(33351..34057)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="99.0"
                     /evalue="3.11e-97"
ORIGIN
        1 tccgcgccaa gattttgcgt acttttccat aagttatcta aagtttgcca gacactcacc
       61 cctccagaaa aaccatcttt catgccttgc aacgcatcag tggccgcagt taaataccca
      121 tccgcattag ttataaacat gattatgatt gcaaattttg atagatccca tactaaatcc
      181 tgcaagggcg tctgagtttt actggcaagt atttgatatc ctttccatag tacatataac
      241 gtaaccgata ccgtcgctaa cgacataata tcattagcaa attgtgtttg ataactggag
      301 ctgattttat ctaccgaatc cataacggta gaattatatt taacgaaaaa cccctgagcc
      361 atatatccac cttttaatca aaagttaatg gttcagcttc tttctgctgt ttaataaagg
      421 cctcttgttc ttgtgtgatc aacatctcat gatctgcttt atttttatta ttccagacat
      481 catactgcat ttttatcgcc tgcattttta acgactgcgc ctgtaatgcg ttagccaaat
      541 cctgggattc tttgatatcc tttgaagcct caattcggct acttaaactc tgaatctgag
      601 acattgcatt tgataactgc ttattgatct catttccctg ttcaatactg gcagccgttg
      661 acacaatccg tgctttacag agattatcat tacgttcata gcccgtatta cacatatcga
      721 aggctccata cttgctgaac agatttttag cctggctgct caatgcacct tcgggattac
      781 tggtaaaatc agaaatataa ctgttcccct gcttataaat atttgtcagt tctgattgta
      841 gattacttag ttcatttgtg aatgccgcaa tattccttat acctgttgcc gtggctaact
      901 ggtctttata tgcctgaatc tgactctgat aatgttgcgc agtttcggac cattgtttga
      961 gtcgttctgt ccatcttgcg gcttcaacag cccattccgg actggcatca atagcaaccg
     1021 gaattcctgc gctactataa aatgaagccg tcaataatga tatcagcata aatgttttta
     1081 cacgcttcat aaattcacct gtcagattgc ccgttcgaga tattcaggaa cccagtcatc
     1141 aggctccatt ccttcatgat aaatactttc aaaaatttcc agattatctg cactagcaga
     1201 caatattttc agatatccac caagtcccga taaatcaagt gtcgcaagtg ctgaaaatga
     1261 tttaccatcc ccctttttaa gactgctttt tttaatcagg aactgtctcg acattggatc
     1321 aagattttta acaatattaa attcttctgg tgtcagctta agcccttcca cataatcatt
     1381 gtaatcggca tcagggttag ccagataaat actggtgctg catacttcaa ccacagcccg
     1441 tgaaatctta ttcttcagta tttcatccgg agactgagtt gccggaataa ccagcccgtt
     1501 cagcttacga attgttttca gcttgttata gacaaagtcg ctgaatgctt catcctgtag
     1561 ccatttccag aactcatcca ggaagataac aagacgccga ccgtcaagaa gctgcgtaat
     1621 gcgatacagc agatagaaag taattggtgc acataccatc ggatcatcaa gaaactcggt
     1681 gccatcaatg ccaaaattat tgacatgctg aatattgaat gtgtctttag cattatcaaa
     1741 aacccagcca tgagcctgac cattagccca ttgggacaac cgaaggataa tcccgttctc
     1801 ctgctcatcc cgatcatctc tctgcataag atgctcaagc attctggtaa tgccatattc
     1861 ccgcatttcg ccaggaggaa aatccatcac agcatcaaca ctttcgctaa taagcaatct
     1921 ttctcttgtc gataatcttt caccatttct ggtacacaga atctccatca gttgcttgac
     1981 aaaaatacgg ttacgttttg ttgcctccag agcaaaagga ttccatcctg tcggctcacc
     2041 gctttttacg gtgtaatatt ccccaccaag cattcggata cataattcag cccctctgtc
     2101 cttatcaaga aagacacacg ttaacttctt attttttgca gaatcagcaa aagtttcggg
     2161 gttattgtat ttctgtaatg aacaggcaag atatgacaga aacattgtct tacctgaacc
     2221 cgccgttcct ataactttag tattagcaag attcttttca cctgtttcat ctttaaacag
     2281 tactgagtta tgtaaattca gataatacgc ctgtttgctt ggtgttttga gaatagcaac
     2341 cgcttctgtc cagcagtttt tatcgcgttt cccctggtag aaattatgga atgatgccag
     2401 ttcgacaaaa tttacattcg ataccggaga taaacgtggc cttaaatgaa aaaccgccgg
     2461 aagctgggca aaatatgccg ctggcaatga catggttgac aatgccggaa taatgcccag
     2521 gtcagtaaag tctgccgtaa ttttacttac agattcgtca agctccctga tactgtccgc
     2581 cattaccatt agcgtgaaat ggtagtaacc aaaggatata tcaccggaca caatatcatt
     2641 ttttgccttt tccagttcct gcaattgagt aaccgcatca tcttctgtac tctttaactg
     2701 tttttccgca cgtttaatgg tactcaatgc ttctgatttg ctcatggatg tatatgaatg
     2761 cgtaataata tagtcagcat cagaatactg gagcacatca aaaacaccgg atgcagtctc
     2821 actacagaaa tctttaattt caatagaacg aaagaattta tttccatcaa tgcggcatat
     2881 ctgtccggta tcatggttaa aaaacacatc cactccacca agaacgttat acaccggaga
     2941 atcagttact ctgatttttt gcaacttccc tgtcagaaga taattataga atgacagttg
     3001 agaagaaaat acctttccgt tctcctcata cataccaaga agtttacagg taaatttatc
     3061 aagagcgcca gagaatgtat taatcatttc attcattctc ttcacatgaa tgttaatatc
     3121 atctttcttt tctttaatac tttttttgcg tttttccagt ttttctacac gcccgtctgg
     3181 tctgtagatc agcgtaaagt aaagagtgtt ccccttgaat ttatttttct tcatcgaacc
     3241 ataataacaa tctgatatta tatcagcata tttattacct gattttgtgg taaaggcatc
     3301 ataaaaactc gccctgcatg aatggttata aaatgaaacg ggcagtccgg aaaatgaacg
     3361 aacaagagtg gcaacctgtg agtcaatagt ttctaacatc tccgcagaga ttgactcaaa
     3421 gttaatcccc atcagttgcc atgtcgctac ataatcaccg ttttttgttt tgacgatgtt
     3481 tttatcaacg tggcttgaat atgggatata tttaccagta gtgattcgct cattcagttt
     3541 catggcatta acaaactcat caatttcaac agcttcatat tgtccggaga ggaacgctcg
     3601 tgcgccaaaa aaacgattac acactgagtt tccgagcatt ttcagcttaa gaaagtaaag
     3661 gttaaaaatg tggtcgtcct gtttagttat cattctgaga acaaaaaccg cgacaggaat
     3721 agccagccag atcagcttgc tgatataaac ccccgccaga aataacgccc ctgcaaccac
     3781 agtaagaggg acgacaggaa cacccacata catagcaggg cgtgtcatcg ctttataaag
     3841 tgtagacata ctatcgtccc cgctttatta gttaaccatc attgatgcaa cttcagccgc
     3901 actggcgata acaattgccc cgatgatgat aggtgagcat tcacgaatcg tgcttccacc
     3961 aaacagaacc ttgtagccga cccacagaca ggcaatagtc accgtgacca gtgaaagacc
     4021 actaagccct gttttaacct tttccagcag cgtttccgct tttgaaaatc catccgcaaa
     4081 ggccggtgat gcaactgttg ccccggcgac tgccataact accttatttt tacgctgcat
     4141 tacagcagtg acagatgaac tgatacgatt acatactgat ttcttaaatg acattttata
     4201 agtcctgtta attaataact tttgttggat gtgagttatc aacaaaagca gatttcagaa
     4261 tggtttcggg ccagataact gacgcattgt gtgaacgatt ttttcgctgt tctcccccgt
     4321 tgcttcttgt acctggtaca acatattttt tttcgttccc tgtataacca attcgctcaa
     4381 cataacttgt attattaaat tctttttctt ttcgcttacc gttactaaaa tttcctgtat
     4441 agtaacaact aagcgcattc tccaggctcc tccctcgttt ataacaatcc acgataatct
     4501 tttcgaaaac agacaagttt tcacacggat caaggagttt ttctgcggac gtggaataaa
     4561 aagaaaaatt actgttggta atctgcatca atccgacaga ataacgtctt tttctgtttt
     4621 caatttctct gataactgta agagcttcct ccttactttt gggcatatga ctgataacac
     4681 ttttgccata gctaccgcgt tccctttcag gaataatttc agccacagca taaggattga
     4741 agccactctc gacccgtgca atatcattta tcgtatccgg atgaactgac gccgcacaca
     4801 gcaacaatgc tgggaataaa gacgccatag ctaacgctcc atatatccat caatacgcat
     4861 actctgcatt aataagtaaa taatttgctt cctcttacta agcaaagatg ttttcgtttt
     4921 ctcttcgata aatgcattca accttggatc gagttttatt gtgacataaa cccctttttc
     4981 cgatgactta tctggtttct ccttcattta atcaatccac tataagtgtg ttttggattt
     5041 gttttagatg cgaacatgat tcgcaaaata acaatgctca acaatacgat caaataccat
     5101 tgacaaaatg gtcatgttat gattcgtgtg atcatgcaaa aaaaagcgcc catatgggcg
     5161 ctttagtatg atttaaacat tagttaatcg aatgtaggga ctggagcatc cttctgagac
     5221 tgaataaaca atgcttgttt aacattctta cagttctgag aatcagagcc agacttctca
     5281 cactctgcct gcttttgttt agcttccgta agatgctgcc cccaccaatc cacacttttt
     5341 acttcttcac tacaaccaac aacgaagaac ggcaaagcaa aaagcagata ttttttcata
     5401 aattccccct ctcactgatc ctggaaagac ttgacacgag aagggcatta gtccgaatga
     5461 gtaccagtgt tctgatccct gccaacgaga cacctcccag ttcagctctt acagaatcaa
     5521 gatattttct gacagttgaa ggctttagtc ctttgaaatc agcaatttca ttcagggtat
     5581 agccataagc gtacatcaga ataatgtctt tttgttgctc actcaaatgt tcttcatcac
     5641 taaaaatttg atgaagtgca gaaatgcaga tagcatcatg ctcagtcatg ataacctccc
     5701 tcgtaggttg ttgtgattag caggtgagca aagtagccgc tttgttcacc tgcgccgaaa
     5761 tcaaattaaa atcccaggcc tttccagttc ctctcttgct gtattcttag ttttttatgt
     5821 tcttctgaat cctttgtaaa cccgtgttca agagcaaacc cgatattgtg accttgctca
     5881 tgttttctgg atagctgctt tttaacgtcg ctctcttccg gctgcctggt ttcacgctca
     5941 tgaacctgac gttctctgtt ccgctcaagg gcaatatttt caatctgcca gttattgcga
     6001 tgcgtttccc tgtagcctgc aacagttcca tcatcattaa acatcgggct acgtacaagc
     6061 gtaggagcca gttttttaac tttgataagc gttcctgcct ggagcttttc agactcgaaa
     6121 tgatttttca ggtctttacc ccaaatcgta acctgctttc caccttttaa agtttcataa
     6181 gtgaggaaag gtgttcgttt ttcccctgcc ttattctgat atgaagtctc cccaaaatcc
     6241 acaaccttgt aaacattccg gagtcttttc ggattttcag cctgtaatcg ctcaatctcc
     6301 cgtttacgtt cgggatcttt tttccatgta gcggtaacat catatcccat acctttcagt
     6361 tttctatgaa aaccgtttct gaactttctg gtttcagact tagtaagtct taatctcctt
     6421 cctgtttctt catcacgaag tttaatatta acatgtacat gaggatgatc ttctttatca
     6481 tcatggtata cggcaacgaa agcatggttt ggataagtct ctttaagaaa ttctatcgta
     6541 gctttcagag cgtcttccct gcttactcca gcttctggtg gtggtgaaaa gaccatgttt
     6601 ttcacatgat cgatgttttc tccacgatat gttctggagt aatcatttcc tttagataaa
     6661 gttgaagtaa actccctgtt aaagtcttct cctttccctg tttgctcgga accttttcca
     6721 tcataacagt aagcctcaag ttcaccatta cgggtaatgt aatcaatacc gtttttgata
     6781 cctgcggcag ttttccctga acctgtgatt ttaaaagtga cttcttttgt tggcgtccag
     6841 gtatatgctt tcttgtctgt gccatgtctg actttatgat taaaagccga tttactggca
     6901 tgtatatgtc ttcccgataa cttaggagat ttcggatcac gcccagtccc tttagcgcgt
     6961 ttaatacggt attcctgttc tacatacaca cccataaatc acccaaatct gttaacaaca
     7021 ctcttggtta acgtttcaag ttttgaatca atttgcttac atagttcaat cacttcaaca
     7081 acgtcttttc tgaaatcagg atcgttaacc gtgcaaaatc tttcaccttt tatgataaaa
     7141 tgaatgttgc gaccaacacg atctacagca gttgataatt ttttaagttc cttaacttca
     7201 tcagggtaaa gacagacttc attctttaac aaagactgac gcacacgaat agcaatttct
     7261 ctgctcatgc tcatgccgtg aagggctgca ttacgtttaa caagttctat ttcatgaggg
     7321 tataaacagg ttttaacagc ctttgatgat tcattgctga cgggtatatt tgatggttga
     7381 acatcaacat taagtacatt atgcctggca aatgtattga tgctggtaaa cccacttgat
     7441 atagcgttat gctctgcaag ttttaactca tcatcactaa gtctgaacgc tatcatcttc
     7501 ataactcacc ccaacagagc ctgcggcagg cacaggcaaa aacatcgttt ttggacaatc
     7561 atggataaaa tgttaacatt ttgaccatga ttgtctatcc tgcattgatt gtaccatatg
     7621 tggcactgtg cctggctata aaatcgtcgc tgcatatgcc cagatttcgt tgctgaaagg
     7681 ttctttcgtc ttcgaccatc tggcaaacgt atagctgata gatttgtgaa agaaaaaaca
     7741 ggcctggcag ggctgggaat tgttacggct gaagccgtaa cgctttttaa gtcctcgctg
     7801 cgctgcgggg cttccggcgc aaagcgcctc ccatgccctt acagggcata aaaaacaagg
     7861 gtaattaagc ccctgcgcga tgattgctga cttctttttc cagagcctta ttaacaaagg
     7921 cattcaacga taagtcttct tccatcgcca tttctgctac ccgacgatgc agttctggat
     7981 caagcctgac gttaaacacg cctttaaacg gggtatcagg ttcctttcca tcctccacac
     8041 aagactgtaa atacagatct acacatagca tttttgtcaa aaaatacaaa ggggcagaaa
     8101 gccccttttt ttatttaaaa catttcatac ccttgcaggt agtttaacca ccaccggaat
     8161 tgatcccatt cactaaattt cattgccgga attctggttt cccagccttt gacaagggaa
     8221 tcagcaagct gtacgatctg ccgcgttgac atttaaaaac ctcattcagt tttgattgtc
     8281 gataacgtga tcaggttggt ggaacaacct gatcacacct tgaatagcca gtcattaccc
     8341 tccttctttt ctatagttac tgtgtatccg taaagggtca aaatgcgata agcatccaac
     8401 gcctcacgct cacttttaaa tgttctgact tcgtgtaatc cattaccttt atcaagggat
     8461 acacaaaact cataatcttc ttctacttct atctttttaa ttaatttatc aagttcggct
     8521 aatgttcgtt ttggctcaaa aagaaatgtg cattgtacaa tggcatttaa atcttcccga
     8581 tcaagctcta acagagcatc attataagca gctttaaaac agcgattatt acgcagatca
     8641 gatgcaaact gcattgcggc ttgttttaac gttttcatga atttcccttg cattgatgtt
     8701 aatagacaat ttcagaatca atattgaaat ttccagaaaa tgcagggttc ccccctgcat
     8761 ttataatgct taacgaaggc actcaataaa atctttaaaa ctcaagcatt catcgccatc
     8821 ttttaacgaa tcaaaatatt tttcatattc gtccctgtag aaaaggacta aatcaacatc
     8881 actctgctta agttcgccaa actgaggaac aattccggtt ttatagtcac gaattttatt
     8941 gttatcagta aataggacaa catactgttg tcccgtatcc ttatgcataa ggataatagt
     9001 gcaaagcgtt actcgttcga atgtgaaaac atgattagtg gttgaagtaa aaacagatga
     9061 gcatttcatt ttaaatctcc tgccctgctg ggctattgtg agaggggcca ttcccctttc
     9121 gatgaaataa taatacgact ttcaagtcgt atttgcaagt gttctcccgt ttttttactc
     9181 gataagtgat tgttatcacg tttttaatcc gcgtaagcgg atggaagggg cgaacgaaaa
     9241 taccagggca gcacaggcca tcccttcacc ctgcaaagcc caactgacca gcaggccatg
     9301 attatgctga tttgcgccgc agaatgccgc agttagcgct cgcgccagcg agtttacgcc
     9361 gtccagggtt cccctggacg gggcgctgta ctgcgcgtgt gagcgtcagc gagctacggg
     9421 cgcaactcca ggtactaata taaaaccatc acaggtcatt ttattttgac tcccttttgc
     9481 agagcacgta ttcaggatgt tctcctgcaa gtaacaaaag aaactcaaac tcaaccagtg
     9541 acagactttg actgttttga gtattaactt cctctttttt ctgccaggtt cttagcccaa
     9601 caccataaat atgactgcat tccttttgtg ttaatcctgc ttttaaacgt aattttttta
     9661 cattttcagg tgtattatcg ggtttcattt aacataaact ccttaattaa attcttaact
     9721 ggcgtctcat cgtctttcct taatccggca cacgtaaaat caatatgttg taattcattc
     9781 tcattcagta cggcatcata caatgtgatt ttcgtagttt tgttcccgat tttaacattt
     9841 gttctggctt ttatcctttt tgtaagcctg taattgtcac cttctttttc aagaaaataa
     9901 gtcacatcac ctttattttt tctcataact gtttcaaata ccctgtaatt ttaacaagtt
     9961 gatctatact caagccccga atctgtaaat cataactgtc gccctgttcg gtgactttac
    10021 cgttcaatcc gttttcagct ttaaagcctg tcaatgcccc ataccagctt tcaagctgga
    10081 caagttgcga taacatacct ttcaggatca taatttcgtc ctttttttcc acctggtgtt
    10141 tctcatactc aatcgcctgt aacacctcct gcgaagcatt taccagaatt tttcgctcga
    10201 tatcggctgc aatatcaacg ggattccgtt ttctggataa cgtgcaaaca tgatgcggac
    10261 tacgccagga gcgactatcc acactcccca caacagaaaa ccggtctttt tccatccgaa
    10321 tatgcacaga gtaattttta aactgcggtg acgtcagttt tatacgagac gaacaatcat
    10381 caagtttgtt cacgcgccag ccgttcccca ggatacggca gacaacttca aagacagggt
    10441 gatattgttc aaaaaaagag ttcatctgtt tccctttttg ctacgtggct cctgttcccg
    10501 tctttttggg ttcgatgccc caaaagacgg gctggctata atatcggggg cttctcgccc
    10561 ccgttctggt tagactctgg tttccacgcg ttgccaccct gtcgccctgc gctgtccggt
    10621 tgtaccgtat tttgcgcgga tttcttctat cgtgtgttct tcacgattcc agtaactttt
    10681 atgttcgtct ggacgataaa accattgttt tttctttgcc gcccatttac acccgatttc
    10741 ttttaaagtt tccttatgtg taatagtttc tccactaatc cagacccagt tacctatcac
    10801 ttcaaatacc agaccagata aaccagaaag aacgtttaat actttttcca ggtcatcacc
    10861 gtaattatat cgagcatgtt catcagtact ctggaactga tttattttat caatatttgc
    10921 catcaataca tcaaaagctg catttaccgc tttcatcagt tcagccccta acgggttacg
    10981 atctggatga tattttaagg cggcttttct gtatgctgct ttgatatctt tttcagttaa
    11041 ttcgccggat aatccaaaaa cgtttaatgc ttcctggata ttcatttttt aaatctcctg
    11101 ccctgctggg ctattgtgag aggggccatt cccctttcga tgaaataata atacgacctt
    11161 taagtcgtat ttgcaagtat tctcccgttt tttttactcg ataagtgatt gttatcacgt
    11221 tttttaatcc gcgtaagcgg atggaagggg cgaacgaaaa taccagggca gcacaggagc
    11281 cacatcgccc cgaagcgcgg cgcagccgct gacgaacgta ccaggatgca cagggccatc
    11341 ccttcaccct gcaaagccta actgaccagc aggccatgat tatgctgatt tgcgccgcag
    11401 aatgccgcag ttagcgcgag cgcaagcgag tttacgccgt cctggtgcgt cgcaacagga
    11461 cggggcgctg tactgcgcgt gtgagcatca gcgaactacg ggcgcaacgc gccagaatct
    11521 gctctatgtt aatgctaatg tatgcataca ttagcattaa cacacgcatc cacatcgcct
    11581 ttaaatgtgt attaatacac accattaaac tattgccagt acgcaattgt acgatttgcc
    11641 gattaaatac cggtgaacgt cgggcgggat aactgcggtt ttgatggcat ggaaattccc
    11701 ccgcttaggg ggaactggag agattagtgg ctggatttac tgagagtgaa ctgtaatccg
    11761 gctaccgatg taagttgtgc aagcgttgtg atggtcgggt taccgttggg ggataatgcg
    11821 cggtaaatac tctgacgggc aaggccagat ttcctggcag cttcggaaat cccccctcgc
    11881 gcctcgatta cctgacgtag cgcaacaaga aaaccaccta aaccaccagg ctcgtttatt
    11941 tcttccaggg cattagcaag ataagcgttt gcataatcag gatctgcgcg caattcttca
    12001 atcatggcgg cattgtgatc aacggatgcc gaataatcat ttttctgcga cttcacattt
    12061 ttggttgctg tcattttttt gacctctttt taaaatcttg cagataacta acggctttat
    12121 ctaaatcggc tgtctgagtt tttttattcc ctccaatgag cagaagaatt atttcgccat
    12181 cttcgattga ataataaacc ctgtaaccag gaccgtaatc aacccgtaat tcccatacac
    12241 cgtccctttc gaatttatga tctccaaaat ttccgcccat agcgcgggca attctggaat
    12301 ccacctttaa cgctgcggtc tggtctttac gtcttaattt tttcatccag tcggtgtacg
    12361 gaacctcacc gttttctgtc tgatatcgtt tcgccgtgta aggcatcttg ccgccctcat
    12421 tcccttaacc tgtgtacatt gtctcttata agtgacaaca gatcaagaaa aatgtctctt
    12481 taaagtgaga aatcctagct ttctggaagg ttctgtaacg cattctgagc attttttccg
    12541 tttcattgta cttagcccta gtcttaacag cgtttaacgc ctctcaacgc tttttagcag
    12601 ccttgttgct gtgatctgta gtcatgatcc ggatagtagt taaatcttga tcaaaatttc
    12661 ttcaaggcaa cgtgtgtttt gtgaataccc cctaaaacgc gctgtatcgc gttttaagcg
    12721 atttttttca tttcgcatgg ttttcctcat ggttgtatcg aacgaagcgg cagagagcga
    12781 ttcagggctt ctctgtgaca ctttggggag gggcattgct ggatctgttg atttatgtat
    12841 cgttgaaatg aagtggtcac ataaatcaat tggcaaaaga atatatcatg ttgatattaa
    12901 aggtatttta ttgaaacatg agaagatcct cggttagcaa aatgaggatc ataattaaaa
    12961 gaactctttc aataaaatca gctagttata ttaaaccgcc ctcggaatga aatattcagg
    13021 ttgtgactaa acatgagaac tttctcggtc ttcacaggat cagattctga tgaacagaaa
    13081 gcctctgtaa gcgtttttcg cgcctcccat gccctaaggg gtatttaaac ccgtttcgtg
    13141 cgcctgagac gcttctgaac gtgttttata ggctatcaag cgactcatca ccgaaggaac
    13201 aacaacagaa ttaccagcga tatgtgagaa atgactccgc tcgccgcagt cgaacgaccg
    13261 agcggagcga gttagtgagc gaggaagcgg aatgtcttcg atgcagcata tgaatccgta
    13321 cgctctggtc tgacctcatc ttgtgatttt gctgattcca actcaaaaaa ttcacaatgc
    13381 gctctattct ttttttctaa tttctttttt ctaaaagata gatcactcct atgttacata
    13441 taatatttcc tttttcatgg tcgttttttc ttttgttttt caattgattg caatgctaac
    13501 tagggacaga tttatggtta aaaggggaca gatttatggt tatttgcgtt tttatcaggg
    13561 gacagattta tggttaaaag gggacagatt tatggtcaac tagggacaga tttagtgtgg
    13621 ataacttttt tatccacagg ttgtggataa ctttttttag attcaactcg gattcgttat
    13681 ggattctcta tgaatctgaa ttggattagt gacttagatc acatttagga tgtttggctc
    13741 gatgggtttt tgatgatgca ttccctcctg gtttgctgta ttgactgcct ctgactgagg
    13801 gtgaaaatgc gccgttcagc caggtttgac ccttcaaaca ggggacagat ttatggttta
    13861 ttagctatgt agggacaaaa aaaaattgcg tccctaattt gggtgtgaga aacttctttt
    13921 gatttttaac tcacaggaag gggagctgta tggtcttaaa gaataataaa aatagcgact
    13981 gtaatgatgt tcaaagtttg ttggcacagg gaaatcaatt gctggaaggt gcatacgata
    14041 taacgctaat tgaaatgcgt cttctgtatc tggcattgac taagattgat agccgtaaac
    14101 cacagcctgc aaatgaatat acattgtttg cgaaggaata cagggacact ttttctttag
    14161 attcgaaaaa ttgttatgaa cagttaaaat ctgctgcgag ttctttaggc tcaaagccaa
    14221 ttgttacgta tgaatggaac gaggcaaaaa aaaggatcga tgcagtcaaa cgattctggt
    14281 tttcttcaat aagatatggt gttgggaata gtgaaagtga cataactttg cgtttttcag
    14341 attcggttag tcaatatctt tatgaactga aaagcgaatt tacacaaatg aatcttgaac
    14401 atatggtgaa actggatacg ccattttcat ttcgacttta ttcatggttg tataaatata
    14461 agaatctgaa cagaaataag aaacatagtg gagtgatctc gacagatcct ataaccattg
    14521 aatggatgaa ggagcgaacc gggcttacag ggaaatatcc agtatataag gattttaaga
    14581 aacgggtgct tgatcctgct gttgatatta tcaatgcaaa tacgaatctg agtgttacct
    14641 atgaaggtat taagtccggc agaaagatcg agtctgttgt gttcacatat cttgtagaga
    14701 atgaaacaca tgatggaaaa aaaatagcaa ctaaaccgtt acgccctcga ttgccatcaa
    14761 gaccaagggt cattaaagga agctctgcgg aggtagcctg ggcaaaaaaa tgtatcgatg
    14821 ttatgaaaaa ttatcttatc tctttaaggg aatatgatga taagttaaaa ttatcaaggc
    14881 cagatcttca gaaggttaag ttatggcatg aaataaccgg atgggatttc gaagagtcgt
    14941 tctggtttag tgattaaaga atgctactgt ttacgttacc tgttttttct ctttttataa
    15001 ctcacttaaa agagaggatg atatgaaaga taacatcgtg gattttcaac gtatcaggag
    15061 agacctgggc gctcattcaa cagatgttgc aaatgatgcc gtttattctg acaaaaagaa
    15121 aacatccagg ttcttttatc tgctgacacc tgtcagatac cttctggctg cttcccttta
    15181 tctggttgtt gttattccat tggggattct tgcgggattt cgtttcttgt tgcagttttt
    15241 aggcggtatc gcagtgatgg ggttaactat cgcctggtac atgggtgcag atgtcagtgg
    15301 ttacattgtt cttgctgcat ggatcgcctt aactgtttgt ggttgcgcag agcagatttt
    15361 tgaatggtgg atcgaaagcc gttttgcgtt ccgtcttttt ggtatcggga gaacgccgga
    15421 agaatgagcg ctgatcttac agacagtaaa gaacaatgca ggatagacaa ttatggtcaa
    15481 aatgttaaca ttttatccat gattgtccaa aaacgatgtt ttttcctgtg cctgccgcag
    15541 gctcttttaa aaggaatatg aaatgatatt taaccgtaat aaaaaacgag atgaacaaca
    15601 gaattcttct gttgttttgc catcaactga aaatgtattc tctgatttta ttaagaacaa
    15661 tccagctttg acaaccaatg cttttacagc cattggggag gttgattgtt ttactaaagt
    15721 acccttactc tcaaataagg aatcagagtt tttaggcatt ctttcacgta atattatacc
    15781 tgattattcc gtttttccca aaatacgact cattgaattt gttcgtcctc atggtagcga
    15841 ggaagctgta aaagaattaa tccgtgaagt gcagaatata acctgtgatt ttgtcctgaa
    15901 atcatatgat gaaacagtcc ttgctgttat ccagtttggt gaaactgcaa ccgtcagaca
    15961 gcaaaagaaa aaactgatta tccagcgtgt gtgtgctatg acagaaattt cttttttcga
    16021 atttaaaaat actgtcgata tgatggggag cgaagacttt tgtcagttcc tgcgagatga
    16081 tgaagagtaa aaatattaga aattaaaaat aagcccacat atttgcgtgc ttaacaaacg
    16141 cattgtcata atttattgtt tgttatcctc taaaataatt aataatggtc ctaacatagt
    16201 tgtaaatacc aatgctgcta taccaatcat accgtacttg tttggtacac atgataataa
    16261 taaagagcac gtagatacag ttatataaaa tattctgaag ttactttttt taaatagtga
    16321 tgatatatat attatacata acgctataag attaaacgcg attgaattta tcattgttta
    16381 atcctctttt aattggtcag cacatatcga tcttaccgcc cagtaacata aaaatgaaaa
    16441 ccgttgttac tgggagcaac attgccagga tgaaaacgat tagattactt ttcctgccaa
    16501 tattgaatac tataccagcc agcaatacta aaaagaaaaa tgcaactggt actgtccatg
    16561 taatgacagg atgatagttt ataatgccta aatcaaagat gcagtgttcc atagattgag
    16621 tgccctaatg tctgattata aactggtatt attacgtatc ctcacttcac aaaatcttct
    16681 ggttttatac ttgatttaaa ctcttcttct ttagaacgtt ctttttgcca tgctatatac
    16741 catacaaaca aaacaacagt tccaatgaca aagtacgatg ctggttccag taatgctgag
    16801 atactgtcac ctgaaaattt ccatgcacca taacccgcaa gaaccagtcc aataaaaggc
    16861 tgcacacaga gcatgtaaaa attgaataca gatttaatta tctttatgag catattttta
    16921 tcccctttaa tagtgtgtaa taaaacactc tatttattca cggttggtct tcctgctttc
    16981 gggctgtttt tccttatatc atcaaacagc ctccgacgtt cttctgctga taccagacgt
    17041 aacgctgcca gtgctgctct gattacttca gcacggcttg caccgtactt gttctggaac
    17101 acctgcgctg tatccagatc atcatctgtc atagtcagat ttatacgcgt tactgcggat
    17161 gccgatgctg gtttttgtgc agcagaactt acaaactggc gtaaatccag tggtttaatt
    17221 tcctgatcta ttttctttgg gatctttgcc ataaggtatc ctttttataa ggtgtgtaac
    17281 tatacacatc atttatggca gggaaagttc cggcatccac gtactgcaaa ttgccaggct
    17341 tggtcagata agccatcccc gccgtatatc gcatcggata tgggtatatt atcaaatttg
    17401 gtgtgtaata atacacatta cagaatatcc gtttctttta acaataactc aatctcgcca
    17461 cgggctttgt ttccccgttt atcatcgtat tcatgtacgc ccataccgtt gttataggct
    17521 tttttatgcg cagtacgcat atagatacgc tggcggggaa ccggaagcca gtctggatca
    17581 tcattgagtt gtcggcgcag ttctgacgct tcactgtctg acgggttagt tgagcactta
    17641 ttcaggacaa tccatgcttt cattgacgga ttgactccgg cctgtgctgt tttaatgtcg
    17701 aaaaccagcc gtcccagtgt gttgatctca atgcctgatc ctggctcaat gaatgtgaaa
    17761 agaatgtgag cacaactcag agctttaacg aacgccggag atttcatgcc tggtgtatca
    17821 acaaacacat aatcaaagcg ggcggccagc ttttgtgcca tagccggaat atccgtgtag
    17881 cattcgaaat acggtatttc tgacagtctg gcgttggttt tacgatcctc gatgaaatcc
    17941 ttgatacttc cctgtgagtc tgtttccagg aaacaggctg ttttcccttt ctttatgaca
    18001 catacacata aggaacaaag cacggtgctt tttcctatgc cgcctttgtg tcctgcaact
    18061 gtaatgattt ttcccatcac aaaatcctcc tggttaaata gtgtgtatta atacacaatc
    18121 ttttgtggtg aaagtataac cgtacaattg cgtgctggca atagtttaat ggtgtgtatt
    18181 attactcatt attaaggcgc tcagggtacc caagaagctg ttttgcaagc tgtggatcgc
    18241 aggtaaagga caggccactt cctgtaagga cgtccagcga aaaaacgcgg gtgtaaatct
    18301 cggtgcttct tgcataacgg tgtcccagca gggattgcag gacgcgcgga ggaacgccac
    18361 tcattgtcag gtgcatggcg tagctgtggc ggaacgtgtg aggagtgacc ggaaccgaaa
    18421 atgttacgcc gtcacgctct gcccgtgcca ctgcggtgtt tatccagttc agcggtgtct
    18481 gtctcgatgt tatgtcccac acaggctgat gtttgatccg ctttttccag gtcgccaggt
    18541 attcccgcat acgcaatgcg tatccggcat ccagaacagg aaccagcctt acagcaggct
    18601 ctggtggttt tctgtatcgc ggatcaggat gtaatggtgg atgtctggtg gtcggacgtc
    18661 ctggtcttct ttctgcttct tttagacgtt gcttgagtgt tttcaggatc accacgggtt
    18721 gcgggtactg ccgcgtcgga gtcagcataa aatcggcagg tttcagcgcc agagcttcgt
    18781 tcagtcgtgc tccggtattc cagagcgtct caaagtacat acgtatgttc agatcatcga
    18841 tgtaggagag aagcagtgag acttccggtg ctatcagata ttttggcatt cctgcgccaa
    18901 tctgtgatgc aagatcccgc atattacggg ctgcatcggg agagatggtt aaattccagg
    18961 cgtcgctacg tgaaatctgg aaaatgctgg cgggtaagtc actcaatttt ttaatctccg
    19021 cacctgtttt tctggacgtg ccagcaatta tgacctgaag cagaggtgcg tccgacaaca
    19081 aaaattccga tcaccaaaaa aaaaatttgg acattttttc cgataatgca tttttgtcca
    19141 ggtggatatg aacgacaggg cagggcgaaa aggaagcggt tatcctgaat aacccaggat
    19201 atgggcacat atgccggaac agggcaccgg ataaaggaac agaatatttg aatgttgtaa
    19261 ctaatgaagt ctggacagaa tgacctgtat gtctaactgc ctgccgaatt aaaccggagc
    19321 gagggtaatc ttgttcaaaa atactgtagc ggtcgcagct gaggatcgcg ctggccagcg
    19381 tgctcgatgc gtcaccggcg agaagctgat ttgttgtttt acagtgagtt aggttgtttg
    19441 cagtgcgaaa aatatcggtg agtatttttg atagagtcat taacggcggt gcgctacgtg
    19501 aaatccgtga aaaagcaggg gatatacgtg gggtattttt cacgtagcaa caccattaca
    19561 gcctaccgtt cagcagacca tccatcattt ttcaaaacca gtgtaatatg ttttgtttgt
    19621 ttctctttca aatcagactc aagtcctaaa aatgcagccc gaacatcatc gcgtttcgcc
    19681 cattcagcga tactggtggg actgaatgtg taattcacct gcgtgatctt cattcccata
    19741 gcatcaccag gttcggtaaa atcaactatc tcatccacct tataatgacc gacgcaaaaa
    19801 tcaggtcgtt ccggagactt cagatatttt ttcccctcat ctgtcagagc atattcacga
    19861 cctggcactt ttttacccgt cttagtaaaa ccaataacgt catcaaccag ggtatttttt
    19921 actgtcaata aatcggcttt gaccagtaca tccagcgcgg aaaactgtcg agaatttatt
    19981 tcatctgccc gttcctgaga tgtgtatcga ttagcctgag ccacagctat ctgaaccgga
    20041 taaggcttac tatcaaacat tcccagcgga ctaatggtaa tgcattcctt ctctagtcga
    20101 gtattaatag ctttttcaaa gttttgctta ttagcatctt ttggtgaatc acaccctgcc
    20161 agcaagaatg aactcaaagc aacaaaaata accactactt tttttgattt gatcatcatt
    20221 ttccctcttt atcaaacgat aaaatttctt gccagcgccg ctggctgttc tgtcccctcc
    20281 atttgccgtc gcaaacttgt ttgcgacggc atcacgatta ttttattcaa cctgcccagg
    20341 ttgcagtttg tcaatgagga aatcttccat gaaatggccc tcatcaagca gcttctgtaa
    20401 agcaagcgga cgcttgccat taccagacca ttctctgatc tcgccatttt catccttaaa
    20461 gcggtattta gcctttctta ctccgccttt ggctttccgc ctagttttca ctgtatcagc
    20521 tgttacagga gcaaggagtg attcgggatc aagacctaaa gatatgatgt attcaatggc
    20581 ctgctgacgt ttggcttcaa gttcctggcg ttcagccgct tcacgttcag catcttcacg
    20641 acgttcttca ataacaacgt tgagcttttc ctgcatttcg agcaactgct caaaatcaat
    20701 ctcacgggca aaaacacgca atgaacgaat attcatcata gtccggctga taatgccgta
    20761 ttcatcttct ttagtcagtt cgctcataat taatcctctt gtttagtgga cgtacttcca
    20821 gacgccggaa ggaaccttat catacagttt attcatcacc agttctgcgc ggcgatgatc
    20881 tgcggcagaa taaaatgcct ctgattctga taaaggcagt ttgtaacggt taatctcaat
    20941 aactttttca agagtatctc ttgatgtaca ttttcttaac tgaaaaagcc attcctgctt
    21001 tgttttcact tcttagccct taccggaaaa cccagcttcc ctgttttctt atcctcaaga
    21061 acaagaactg tatcatacgt tccaccgctt ttctttttaa atcccttaat caaatcggtt
    21121 ttccctgatt taaccagttt ttctgcctgc gcctgggtga ttttcttacc agaaaactca
    21181 ctccagattt taaattcaca tccggtacag aaataacctt ttggtctgat aacaatatgt
    21241 ttaccacagg aagggcaggg agagtccagg cgttgaaact gccctgctgg cgcagcgggt
    21301 tcaatcttca tctcgcccag gtcaacatca gaaatcatgc ctgtcagttc accgtacagc
    21361 tcattaataa actcttcaac cgtcaggtcg ccattttcaa tggctgtctg cttttcagac
    21421 cataatgctg tcatatcagg attaaccgct ataccaggca gggcatcaat aagcgcatat
    21481 ccggtatcag taggaataag tttccctttt tccagcgtga tatagtttct tttcttcagt
    21541 gtttccagaa tggctgcgcg ggtagctggc gtaccaatgc caccatgttc atcttttttg
    21601 tctttatcct tatctttcag caatttctta atcgttgggt cagtgacaaa atccgcgacg
    21661 cgaacaagcg cagcaagcaa ggaggcttcg gtaaataatg gcggcggtgt tgttttcttc
    21721 tcattaacga caacttcttt tgtcgtcagt gtttctcctg tgcgaatttt acagagcagt
    21781 tcaaaagcgg aatcatcatt atcttctgat tcaccttcgt ctgtggtttc cgcgccaaga
    21841 aacgcctcaa atccgctgtc agttgttttt ctggcacggg catagaacga ctcatcacca
    21901 cactgaatgg caaccgatac ttcctggtat gctttttcag gcatgaactg aacaagatag
    21961 tgttgtgcga tcgccaggta aacattgcgc tcatcggtgc tgagtgcgtt aacatcaggc
    22021 acactggcgg tcgggattat tgcagtatgc gcagtcacct ttgcactgtt aaacgctttg
    22081 cttttacgtg cagaatcaat atccagcgac tgaggaaaga ctgatttcag ggcatcgata
    22141 acctgcggcg cttcgctgaa ttgttcatca gaaagatatg agcaatcaga gcggttataa
    22201 gtaatcgctt tatatttttc acgtaattgt tgcgtaatat ccagtgtttt ttgtgccgtc
    22261 attttgaact ttttgttcat gtattgctgg agtctgacca ggttaaacgg caacggtgca
    22321 gccgtttttt tatcatcagt tgctgccgct tcaactgtag ccggttttcc tgcaagggat
    22381 gctgccgttc cgtctgccca cgctttatca agtaatttac ggtctgtcag cggagcaaat
    22441 tcccctggtt tccagttcgc cctgataaca tcagcaccac gctgaaagac tccggtcatg
    22501 gtgtagtaaa aactggattt atggttctgg ttagcacggg tacgattcac aatcaggcca
    22561 agaacgggag tctggacgcg cccgacagac agaacaccct gatatcctct ggcttttgcc
    22621 ggaatggtgt aagcacgcgt catggagaag ccatagacgg catcagcaac tgaacgcgcc
    22681 agcgccttaa ggtaaagccc tttgaaatca cgattatctt taagatttgc cagtgccttt
    22741 ttcactgccg gaagcgtgtt gtcgttaatc agaacgcgct ttacgggttt tgtgtttcct
    22801 gcatattcca ggacttcatc aacaagtagc tgtccctcat catcaggatc gccagcgtga
    22861 acaatttcag tcacgtctcc acgtctgata agctcgagaa tcgttttaac ctgttttgct
    22921 gcactttcaa caggctgata cttcacggga taaagacgta aaggaagcgt ttcaaccttc
    22981 caggctttgt attcaggatt atagttttcc ggcggctgtg attcgataat atgaccaaaa
    23041 cagttagtca caatggcgtt atcactttca aaccagccat catggcgggt aaaattgcca
    23101 ccaagtgcct taacaatatc atttgctact gcgggttttt ctgcgataaa aagtctcatt
    23161 ttgttatcct ttacattgaa ttaatctttt ggcacaacgg atagcgcgtt cttccgatac
    23221 tgtatgttgc cagttatctt tacttactac tctgaatctg cgctcacagc cattaaaggc
    23281 aaaaattccc tcacggttaa gtatattagt tgcaatatcc cactctttaa ttctcaaaaa
    23341 ggctgttaca gcaaaaccag aatacgaagc aatttttgaa atgatgcatt catcagcttt
    23401 tattaacgcg gcaaaaggaa ctatcttttg atgaccacac gaaatcagag ggagtgtgtg
    23461 aatatcataa taagctattg aatgacaatc catgcgggta tcatcaatag ctgccagcca
    23521 gaatcctgcc tggtctttta tttttctgct aatatctgaa tctgaaacac cagggtttaa
    23581 taaatatcca ccataacaga tatggaaggg gtgaacagat tcatcaatat caggaagttc
    23641 ttttaccgga ttttctttcc agtccttcag aacaccaaat tcaagagcat ccagcaaaaa
    23701 ttttcgttcc agcgcatcaa ctaatgcata ttgcatgtgt taatcctcca ggtaacttaa
    23761 atagtcaggt tgcgccccgt tctttttata aagctcttcc ctttcctcta tatcttcatc
    23821 tgcttcctgc acgctcagat caagggttcc tttcaaaaag gcacgagcat tttttattac
    23881 atccactgat aattcatttt tggttccgcg aatcattccg attgcgatat taataatttc
    23941 cttgatttca gccggagtcg ttctgtccag cactgcgcca agctctttaa ggtcaatttc
    24001 tacatcttct ggtaagtaca ttttggcgca agcggcagca gctttggttc tgaaagcacc
    24061 tacagagatt atcctgtcaa ttcgacctgg acgtttccta atacgtgggt cgatgcgttt
    24121 tggatagttt gtagaaaaga tcacatatgt acctgcgaca tttcgcggtg tatcagctcc
    24181 atcaagaaaa cttaacgttc cggcatcagc ccgataaagt tcatcaacct cttcagctat
    24241 aataatgacg ggtattttct tctgagcagc agcgtagcaa acatctttaa agtaatcatc
    24301 ggcataaaca aaaacatact tatcctgata ctttgccccc aaagcttttg cgatagttgt
    24361 cttgcctgtt ccaggggggc cagtaaagag cactttacgc atacctgact gaccataccg
    24421 ggtatagaaa tcaatatcag aaaagaactg attaaagtcg ttttccagct cgtcaaattt
    24481 tggatgaact gagaaacgca tagcattttc aatttcctcc tttcttgcct taccgtgata
    24541 ataaacacca tcatagtacc caagtttcca gataccttta cgtggcaatg agcggtttaa
    24601 tttagcgcgt cctgcctcgc aaagattgtg gagcattgac atacttttag tagtcccaac
    24661 ggcgtactcc atcctgactt tagagttaag aatgaagcga ataatatgaa caacttcatt
    24721 ttgaccaaga tgaatcctgt atgcaccaga accatctttg aacataagtt ttttaattct
    24781 cccagcttta gccataacag ggttacttcc cgtatgaaca acggttgaag caacaggttc
    24841 gatatccaga ttcgaataaa ttttacggtt ctttctgttt ataaaaatct ctgccacttt
    24901 aggatagtaa tcacaatcct ttacgacagt tccaaaatta tcttcaccgt aatattcttt
    24961 gtgaagccgt aaagcctgct ctaccagagt taatttaccc ataagcgcac catgtatatt
    25021 taaaaccgtg acactgcctg aaatttattt aaggtagtgg aggggttgga caagcaacgc
    25081 gcgtcagttc tgtttatgtc gccattccca cggtggaacc ggattactgt cagcccataa
    25141 accacgcttt tgttcctgcg cttcccgttg caaagccggt aatgatttat ctgtgttgta
    25201 acgttcatat acccatgcag cgccagactg aaccataaag cggctggcat ccgtgccgtt
    25261 cgtcgtgaac acacgaccga taatgcgtcc gtagcggtct gtctgcgtat aagagacggt
    25321 aactgattgt cctgcgagca gagctttaag ctgatttgct gaccagtgcc cgaaagcctg
    25381 tttcttttca ggagcatcga tatttatcaa tcgaaccctg atcggaactt catacacaac
    25441 aattttcgcg ggtagtgttt taacttctat ggtgtcgcca tcgagaacgc gaataacttt
    25501 cccctggatt tcagccgcac acaatgtagc tggtaacagg gaaacaacaa aggaaagagc
    25561 cttaagaaaa tgtctcattg ctttcttccc tcccatattg ctgagagtat tttacaaatg
    25621 gataaaacgg cgattaaagc cactgcgata acagccaacg aaggaagtac atagctatac
    25681 aactcaacta tgaaattaag aaattccatg agcgattgcg gctttaaagg atcatcccat
    25741 aaaacgataa caacacgata aagcccatag acaattgccg aaaaccagac cataaacagt
    25801 aaggcctcag taaaaacata agcgaccgtt ttaacactat cgataatttc aattccggca
    25861 actctcacac ttcttgcttt catatatacc tcatggataa cgggaaacta acgcccttcg
    25921 gttgttcaac cccgcaaatc ccagattaaa atctggaatc tgcggcgttt acctttatcc
    25981 ctgttcagaa ggattctgga taaattttat ttcatcgatt tcctcaattg aaatacgctc
    26041 tggtatagtt ctagagcaat actttgtgaa agaagtttct ttgcagttac ctattttacc
    26101 gggaacgatc gttgccacgt agttctgaat gatggcgttc atagtcttat catccaatgc
    26161 atgagcagga ttaccagcta taaagccaga gtgacctgtt tttattgcat taagaaaatc
    26221 aaccttttct ttattttgag cattctgtga gtttgacagc gcactattgg ctatgccttt
    26281 tacaccatca acacaatccg aaatattaag agtttccttg ttacctgtaa ggtaatactc
    26341 acaatctgca tatgcactac cagcagataa gcacaataaa acagctataa tagatttggt
    26401 tactttcatt tctaacctca gtgattgtaa ctaatcatca cattccgttg gcgcggtatg
    26461 tgatacttgc agtcccctga tacccgttgg cgcgggtatc aggttttaat cagcccttaa
    26521 cgcgtccgaa cttactcata atttttgaga tagcagccgg atcagccgtt gaacactgat
    26581 tcagaaatgc tttacgggca tcaaatgttt tactccagcg aatgcttcct tttttctttt
    26641 tcagaatatt aaaaaaatcc ttttcagcac ttctgcactc actccctcca ccttgcccga
    26701 ctgcttttcc atataagcaa agtaccgaag cgcaaggatc agatgcatta gcatttgttg
    26761 atattaatcc taacgccagc aaggcaggta aaaccactct attttttcca gtcatttttc
    26821 acctcgtttt gtgctttaat gaaaactatt tttccctgtt caggtaaaaa acttttctcg
    26881 tttcgccact ccacgactgc tgttgcccct tccatcttca acagatctct gattcgaaac
    26941 cacagcccag catcatgtgt tgtcactaca atcctgtccg catgagccag agcgtaataa
    27001 aacgtcggcg ttctggcctg tactccggat aaggaagtga tctcataaac ccatccttta
    27061 ccgctaacgt ctgactttat gacaccgtga aaatcgggga catatggcaa tgagggattg
    27121 atcacttcat ttgccttttc aaactgcacg ggtgttggct ctggcggtga tgaacaacca
    27181 gcaaggatag aaatcaataa aaacactaac ttcttcatca tgttctcctt tatgccgctt
    27241 tatcgagatc aggaacttct tttactgcca gatacccttt tgcgacgatt tcattttcaa
    27301 atactttctg tggaggcata accaactttc ctttcttcct ggggaaaatg tttgcaagtt
    27361 ccggagcaac cttcacaaaa tcaccaaaga aatactcatg gagatagtag aatgcctttt
    27421 cacaacgaat cgggttttct cccttcattg ccaggatttc ttcactaaat ttcagtgtaa
    27481 gtagttcatt tgttgttacc agtggacgct caataaggct ttctgattca gatctcgatg
    27541 ttcctccacg actacgactt ttgcttttcg aaccgatagt tactgttcgt gttcccatcg
    27601 cttctgataa ctcccgcgca tctttaacat cagaagcgga ataaacgatt ttacagggtg
    27661 cacttgccag taatgtttta ctgcctgcat aactgtagat ttcctcaagc tgagagccga
    27721 cctggtaaac aatcaacaat ttcagcttgt aaccagcaat gagtccagat ttactcttga
    27781 tgtaatctac agcaccaatt gacgggaatt catccagtag aaaaaggcag tcatgtttta
    27841 tttccggatc atccgttggc atcttttcaa gattcacctg tatagcaagc tgaaagaaaa
    27901 tatttgttat tttttcagcc aacctggcat tatcaccaga aatacagaaa taaattgtca
    27961 tccgcttttt ccgcacctgc cgcaaatcaa aatcatttcc atcagtagca tttgccacat
    28021 tggggttagc aaacggtgat aatccattaa gaaagttgct tttgagttgt gcttttgttt
    28081 tatcctccat ctcaatgaat gccttaaggc cagcgacacc aatatcagca agcgttttgt
    28141 ctttccccct taattctgaa cgaatatcat tcatgaatga aagaagatgt tcgggttctg
    28201 cacgctcaaa aagctgatta attttagaca ttgagaagac aggctcaata tcaagcgttt
    28261 ttagtccagc cttatcattc ttaatcataa accataaagc gacagcataa gatttaaaaa
    28321 caccccccgc cgtcttatta agatagctac cagcatccgc accatctgtc ttataggggt
    28381 aaataatcaa cgcaagattt tcaagctgat taaaaccttc actcgttccc atgctgacat
    28441 aatacaaagg gttaaagcgg tgcgttaccg gactaaaggg atcaaattta taaacctcat
    28501 gacctaaaat caccttcctg ataagactgg tgatattaaa acactccctt tttggatcga
    28561 gaataataac actccaccag tacttcataa gattagtgat gactatacct gcacctttac
    28621 cagcccttgt tccggctccc atcgcactga atgctgctcc cacatagcgt atgattttct
    28681 tgtcttttat accaacgata atcccgtctt tttcgtcacc gtcaagcgtg aaactgttag
    28741 actcacgaat atcattagtt gtcgcaaatc gcgcatcacc aaaaatatta tctttcttct
    28801 cgttcagttt tatcaacgcc gcaacaggga taataagaga cacgacaaat cctgctccaa
    28861 gtgcaacaaa ggctaaaact ctgatatccg tagtcacaac agataaagta aggctgtctg
    28921 taaaaatatc catcctgtac gcatcaatgg atctgaacac agccttcaat ggtttcagat
    28981 tctttatctg gctgaagtaa agcacaaaga aaataaatga acctgcaaac catgccgcaa
    29041 caagcataac agcgaatata aaaacagatt gcgacttatt aaaagttttc acattcagcc
    29101 cctttgtaat agatgtcgct catatgcctg acaacaccat ccctgcctac atgaacaaca
    29161 atatcaatac tgtccataat gattttacga agaacatcaa aaggaagatt ttgacattct
    29221 ctgttctgat aacattttgt caccatctga atgatggcat cttttgccga ggccgcgtga
    29281 atggacgtca tgcttccact gtgaccagaa ccagcaactt tcacaaaatc ccaggcatcg
    29341 ccacctttaa tttccgccag taaaattctg tcaggtttca ttctcaaaca ggatttgatt
    29401 aatttcgctg ctgttatgat agagccggaa tcactgccgg attccgaagg gtaaaaaaga
    29461 tgcacataat ttttatgaat aaaaaatttg atttcctccg catcttcaat cgtaatcagc
    29521 cgcgtattca atggtatgaa atcgataaga ctcttcatat aggttgtttt accggaaccc
    29581 gttgctccgg caaatacaat ggttttccct gctgctacgg caagctccat aaaagcagcg
    29641 atatttctcg ctctgaataa atcaagaagc tcatcatcgt atgtcctgtg tttttttcct
    29701 gactggacat aatcataaaa accgttcgcc acatattctt tatgcgttat ctgccgtgtc
    29761 gatggtttac gtatagtgat tgaaatagta tttctctcac atgcaggagg aaaaacgacc
    29821 tgtacacgtt ctcctgattc cagtgttgct gaaagtaatg gcttggtatc gccgatttca
    29881 tctccccgaa atgatgccag cgtctgagaa aaacgtttac aaaaatcaaa ggtcacaccg
    29941 tcattattat ggaatgtcca gtcaccatta atttccgtcc agatttcacc aggacggttg
    30001 acagcaattt ctgttagccc ttcaatatca agaaaagact ggaatacttg atttttataa
    30061 aaatcgagcg atttattgct aatgctgaca ggaataacgc cactcatact attttacctt
    30121 taactcatag atatcagaaa aatcaatgtc ttccccgacc ataatagtga ttatgtcacc
    30181 ttggttttta tacattgttg gaggaatatt tatcgaattc tcaagtgcaa ctttagccat
    30241 ttcagccatt gcctgtcgtg agttttcggt ataatccaca ttacgatctt taccaggtgc
    30301 attatccgcc gccgccgccg ctacatcctg aaccatactg agcataagag aaccaccaaa
    30361 acgctcccag aagtgagaat cgatccatcc atcaatgcct gcttccccca ggggaccagc
    30421 cgctgctgta tttaccatat cgattcgttt attatcaggc gtccgcaact gctcccacat
    30481 aacgaacatt ctgccctgtc catgattcag cgttccggtc tggtaacgac caaaagcctt
    30541 agttccctgt tccagtaatt ttgtgtggtg attagcactc catacatctt ctgtaaaaac
    30601 acaactgata cgacctgcaa catcagaaac aaagcgtgtg gttaaagcac acggtataag
    30661 cctgttttcc tcaatataga gatcaggatc gagattaatc gcagtcactt tcattcctga
    30721 tttaccaggc acattttctt ttgattcttt cctttcttcc tgtggctctg atgtctgcga
    30781 tgtcctgctg ctgccactcg cgccagtctg actccctccc tgaccagcaa caggtattga
    30841 caaatatttc ctgaacccct cctgtggcac ttctttatga ccgtcagaaa cagtattacc
    30901 agaaccagta gcgcctggat tgataattgc tttgttctca acagggtcaa aattctgacc
    30961 aagaccagta cggattttac ttacctgaga aatgctggta tcgcctgttg attctgatgc
    31021 tttctgctgg tcatctgcaa aataattttt atatgttttc agcgcaaaaa taccaataac
    31081 taatacagcc atcagaccaa acagaaagcc agaacgcata cgattatttt tgttcctgat
    31141 atcaccgata tcatgaacgg gtttactttc cagctttgac tgattcgcat catcaactaa
    31201 atcatctgtt tttttcatat cagtcattat tcacctcaac acgttctacc gcaggagaag
    31261 atgtattcct ctggtcggtt aatacttttc cgaaagattt attcacaaca ccaacaacgc
    31321 tgtttccata gcgtaaaaca aatttgtcat taacgttgtg gataaccatg attttatact
    31381 tgccttttgt ttccacatta aaagcaagtg tctgttcctg accatctctt acagcaaatg
    31441 gagctgggaa tactttccct gagttaaaac ctaaaaaggt aaatatgcca ttatcataag
    31501 caaaatcagg ggcgatacga cgactgtcat atttttcatt gactcgcatg aaataatccc
    31561 agtttttagg cgcatcggct ttttcaaaac tttcagaaat cagtttcttc tgtctgagtt
    31621 tttcctgttt ttcttttgcc agccttactt cttctgcatt ctttttcgct atttctgatg
    31681 gatagcggaa ttgtacaaca taagcaggtt gcgcttgttt ttcttctgac agaaggatta
    31741 gatcaagact gtaaatccgc tttgttgttc tgacaaaaag attcgtgtcc cattcctttt
    31801 ctgttggctg gaaaaccttt ttcagttttt cgccttcatc gccttcctgt tcctgaacaa
    31861 cgggacgcgg attgatgtaa acaacattat catcggttgt gatttcccat ccggcaggaa
    31921 aaccagcctt tgcactgata acagcctcac cttcatcaaa aacaactgat gtgagaaatc
    31981 ctgtctttga ccggataacg gtcgtattcg caccgttata actcacagtc tgcatccttg
    32041 catcaaatcc agaaggtaac ggagtcgctg ctgaatacac aagcccagga agcaataaac
    32101 atgtagcaat aaataatttc ttcatcattc ccccctgact tcccgatctg tctggtaact
    32161 ggttaccgta aaaccgagag gattaagctc acgactggaa cttttaaccg acttttctgg
    32221 ttcaaaacga tatgtcacac gagccgtcca gtatgaaact gaaacctgtc cggtcgtgaa
    32281 gtttctcgtc gtttttttaa aacgcacaga ggccagttta tctggcgcgg ttgcgtcaga
    32341 aataatattg gagatgacct caaccgcaac gtaagaaccg ttattatgat aaattttatc
    32401 aggagccata tcgctgttat acagacgaag ataatcgtcc tttactgtat tcgagctata
    32461 tagctgtaca gtctcataat catactgaag agacgggtaa ttataacctt cacgtaaagt
    32521 aatatacgtg tttacaaaat accgcccaag cgcttcagat tgcaggatct tttcctgttt
    32581 aacctgagta atcagttctg tacggcctgt tttttcgcca acagccacaa tagcaagctc
    32641 tttttctttt aatggcacaa gaacacaaat tgcagcccca agacataagg acagtaatga
    32701 tgctgccact gcaacacgcc atgcattttt cttagaccgt tcattttctg catagagttg
    32761 tctttcgaag gatttagctg tctcaatctt cttttcgatt ttttcactca taactgatta
    32821 cctggctgtg gttaatgggt tccagttcgc cggaaacatc agaaggaagg gtattccttg
    32881 tggtacatcc ggaaatctga aacaggaaaa acaaaagaat cacacatcgc ataaattcac
    32941 cttattaagc gttcacgaac acctttaaga gataaaggcc aagatgaaga aaaagaatcc
    33001 caccaataag aagcaaaaag cgaagatcca taccctttct ccatttcccc gcaagcccta
    33061 aaccaagtct tattcctgcg aagcaggtaa acactcctaa aagaaggatt aggacaaaat
    33121 aaagtatcat gacaaaataa tgaagcatgt cacaaccagc tctgactgat tccacctaag
    33181 accttaaata aggtaattcc cgtgattaaa ataataagct gggttattag ctttctcttc
    33241 ctgctccatc cggaggtgat atgtttatca acaaacgtca gtatccagtt cagggacatc
    33301 acataaaaaa aacgtttcat tatattcatg cggcattcct cgctcgtgct ttttccaggg
    33361 atgcaagtct tctcgccttc atccccaaag cacctgtcgg agccagcgcc tgatatccct
    33421 tttcacccgc ccattcagcg gctgttcgcg caccacgccc catcagattc cctgctttcc
    33481 cagataaaga attcatgccc gttcttccgg ccatccctaa gccaaaacct aaaccagcac
    33541 gaccgccaag catcagagac ttaccagtag ccataccagc agcacccagc cccatcatgg
    33601 ctgcgccctg aacagcacct tcaacacctg cacctgctaa ctggacagca aaacctttag
    33661 ctataagaac caataaagcc cccaaaaacc cagccataaa gcccatagca cctgtagata
    33721 caagatttac atttcctgtt tgtgcagcac gaatagcatg ggaaaggatc atcccttgaa
    33781 aatccattgc tatccgaatc actaaactgg caaatagaac tgtcagaata ctggagaata
    33841 acgattgtaa ccaattatta aacatgctcc gaataaaacc aaacataaga caaaagataa
    33901 atatcggtgc tgtaataatc aggagtttca tcgttacatc tgctgttaaa aaaacaacca
    33961 cactaacagc cattaaaata agcgagccag tccatattaa aaactgtcca actacacctt
    34021 gatctttaac atatgttgat ttatctaaag agtatatt
//
