LOCUS       NZ_CP086506            33826 bp    DNA     circular CON 28-MAY-2024
DEFINITION  Escherichia coli strain Ec-050-T5-MAC plasmid pEc-050-T5-MAC_6,
            complete sequence.
ACCESSION   NZ_CP086506
VERSION     NZ_CP086506.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN22108722
            Assembly: GCF_022759725.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33826)
  AUTHORS   Moser,A.I., Endimiani,A., Campos-Madueno,E.I. and Vallone,A.
  TITLE     Genome plasticity in E. coli and K. pneumoniae: SNV accumulation
            over time
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 33826)
  AUTHORS   Moser,A.I., Endimiani,A., Campos-Madueno,E.I. and Vallone,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-NOV-2021) Institute for Infectious Diseases,
            University of Bern, Friedbuehlstrasse 51, Bern 3001, Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 275x
            Sequencing Technology :: Illumina NovaSeq; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022759725.1-RS_2024_05_28
            Annotation Date                   :: 05/28/2024 05:24:20
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,280
            CDSs (total)                      :: 5,158
            Genes (coding)                    :: 4,888
            CDSs (with protein)               :: 4,888
            Genes (RNA)                       :: 122
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 89
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 270
            CDSs (without protein)            :: 270
            Pseudo Genes (ambiguous residues) :: 0 of 270
            Pseudo Genes (frameshifted)       :: 108 of 270
            Pseudo Genes (incomplete)         :: 174 of 270
            Pseudo Genes (internal stop)      :: 53 of 270
            Pseudo Genes (multiple problems)  :: 57 of 270
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP086506.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..33826
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="Ec-050-T5-MAC"
                     /isolation_source="stool"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pEc-050-T5-MAC_6"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018"
                     /collected_by="Institute for Infectious Diseases Bern"
     gene            join(33010..33826,1..212)
                     /gene="virB11"
                     /locus_tag="LNN49_RS25920"
                     /old_locus_tag="LNN49_25925"
     CDS             join(33010..33826,1..212)
                     /gene="virB11"
                     /locus_tag="LNN49_RS25920"
                     /old_locus_tag="LNN49_25925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401678.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_000017224.1"
                     /translation="MSGVIPVSISNKSLDFYKNQVFQSFLDIEGLTEIAVNRPGEIWTE
                     INGDWTFHNNDGVTFDFCKRFSQTLASFRGDEIGDTKPLLSATLESGERVQVVFPPACE
                     RNTISITIRKPSTRQITHKEYVANGFYDYVQSGKKHRTYDDELLDLFRARNIAAFMELA
                     VAAGKTIVFAGATGSGKTTYMKSLIDFIPLNTRLITIEDAEEIKFFIHKNYVHLFYPSE
                     SGSDSGSIITAAKLIKSCLRMKPDRILLAEIKGGDAWDFVKVAGSGHSGSMTSIHAASA
                     KDAIIQMVTKCYQNRECQNLPFDVLRKIIMDSIDIVVHVGRDGVVRHMSDIYYKGAECE
                     NF"
                     /name="virB11"
     gene            199..2061
                     /gene="taxB"
                     /locus_tag="LNN49_RS25925"
                     /old_locus_tag="LNN49_25930"
     CDS             199..2061
                     /gene="taxB"
                     /locus_tag="LNN49_RS25925"
                     /old_locus_tag="LNN49_25930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxB"
                     /protein_id="WP_000847103.1"
                     /translation="MKTFNKSQSVFIFAVMLVAAWFAGSFIFFVLYFSQIKNLKPLKAV
                     FRSIDAYRMDIFTDSLTLSVVTTDIRVLAFVALGAGFVVSLIIPVAALIKLNEKKDNIF
                     GDARFATTNDIRESNSFTLDGDEKDGIIVGIKDKKIIRYVGAAFSAMGAGTRAGKGAGI
                     VITNLMKYWWSVIILDPKRECFNITSLIRKVILGHEVYKFDPFSPVTHRFNPLYYVSMG
                     TSEGFNQLENLALIIYPYKTDGADAGSYLNKTAGGVFKSYAVALWFMIKNDKAGLKTLD
                     IEPVFSMSKINQLFERAEPEHLLSFMNDIRSELRGKDKTLADIGVAGLKAFIEMEDKTK
                     AQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNARLAEKITNIF
                     FQLAIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQV
                     GSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGSKSKSRSRGG
                     TSRSESESLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYLHEYFFGDFVKVA
                     PELANIFPRKKGKLVMPPQKVFENEIVAKGYLAVKEVPDLDKAA"
                     /name="taxB"
     gene            2070..2492
                     /locus_tag="LNN49_RS25930"
                     /old_locus_tag="LNN49_25935"
     CDS             2070..2492
                     /locus_tag="LNN49_RS25930"
                     /old_locus_tag="LNN49_25935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_001328552.1"
                     /translation="MMKKLVFLLISILAGCSSPPEPTPVQFEKANEVINPSLPYVPDFH
                     GVIKSDVSGKGWVYEITSLSGVQARTPTFYYALAHADRIVVTTHDAGLWFRIRDLLKME
                     GATAVVEWRNEKSFLPEQGKIVFIKAQNEVKNDWKK"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            2476..2781
                     /locus_tag="LNN49_RS25935"
                     /old_locus_tag="LNN49_25940"
     CDS             2476..2781
                     /locus_tag="LNN49_RS25935"
                     /old_locus_tag="LNN49_25940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000147044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_000147045.1"
                     /translation="MTGKNRVVLPALLALGLISTNANASDPCASVLCLYGKAVGQGGGS
                     ECRSAEKDFFNILKKKKGSIRWSKTFDARKAFLNQCSTADPAAISKIMSKFGRVKG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            2836..3084
                     /locus_tag="LNN49_RS25940"
                     /old_locus_tag="LNN49_25945"
     CDS             2836..3084
                     /locus_tag="LNN49_RS25940"
                     /old_locus_tag="LNN49_25945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001290044.1"
                     /translation="MSEIRFVTLESDFNNIKEIYSDDELNRLLEAVNQNCPTRIVLGSV
                     EKGKETPLKWCFRTIPERISIEEIDEIKFIQNPSEQG"
                     /name="hypothetical protein"
     gene            3176..3484
                     /locus_tag="LNN49_RS25945"
                     /old_locus_tag="LNN49_25950"
     CDS             3176..3484
                     /locus_tag="LNN49_RS25945"
                     /old_locus_tag="LNN49_25950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000647577.1"
                     /translation="MKARSVRVAGIEIIDSVKTVAYVFTEALLFMVWFSAIVYGLYRVV
                     IVLWDDPLKPQSLMEFLNFIVELYSYVLPSLAVIAVALIAVLSICKILSAIWEGRKQ"
                     /name="hypothetical protein"
     gene            3481..3975
                     /locus_tag="LNN49_RS25950"
                     /old_locus_tag="LNN49_25955"
     CDS             3481..3975
                     /locus_tag="LNN49_RS25950"
                     /old_locus_tag="LNN49_25955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="WP_001215681.1"
                     /translation="MRHFLKALSFVVSLLPATLCAAEIQGKVIRVLDGDTIEVKTLPAK
                     IVVYEVPIRVRLINIDAPEKKQAFGHWSANQLKALLAGQSVTVSYTQTDRYGRIIGRVF
                     TTNGTDASRFMVQSGAAWVYERYNTDKSLPALQREAQEQKRGLWADSNPVPPWEWRHKQ
                     N"
                     /name="thermonuclease family protein"
     gene            4057..5319
                     /locus_tag="LNN49_RS25955"
                     /old_locus_tag="LNN49_25960"
     CDS             4057..5319
                     /locus_tag="LNN49_RS25955"
                     /old_locus_tag="LNN49_25960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517490.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000517489.1"
                     /translation="MGKLTLVEQALRLHKEYYGEDNFGTVVKDCDYYPKVAEIFINRKN
                     RKIYSNLDIEPVASTVVHTGSNPVMAKAGRIKKLMFKDGSGAYRIHLGQNEVVHIIRFI
                     LNSKVRMEYAVGTTKSMSMLHNLCEAGRAKLNRSLPRKGIWKLGYYDGVYYHGKARKEE
                     IENAMRFSVHPKFDELENDFNQFFSDIDFYTRYGQSGMRKVLFTGPPGTGKTTIAKALG
                     AKYQDKYVFVYADDYFKDVCYAAAQKKIPVIIIAEEVDELYRADAGTLSFLDGADTPRN
                     VAGTYVIFSTNYPKRIDPRIRKRPGRIDRIISVGAFRTKAAAACAKMYLPEDVEIDLKE
                     LGAVLDRTTPAEIKEIINIAIGMIRGTKNELSVDVIKNARAFLKGTLDLSVQEADEDIE
                     EREELYKKNGAQPDYLSYLED"
                     /name="AAA family ATPase"
     gene            5323..5895
                     /locus_tag="LNN49_RS25960"
                     /old_locus_tag="LNN49_25965"
     CDS             5323..5895
                     /locus_tag="LNN49_RS25960"
                     /old_locus_tag="LNN49_25965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001199073.1"
                     /translation="MQYALVDALERKFLLDALEFGVLKDWKENPVKELPDIDESVHPFH
                     ICYGGYLLNPGVSDSDISRKIKDQAGFWLAAIDDTRMDCHSIAYYDIHTLPLISCGHQK
                     IVPFAALIKADECIISKIASYSGFAVTAFLRIKEWDIATNILNREGIFAFNGCERRFRV
                     VSKDNWQHTVSEERAIRCAKRLIQCKG"
                     /name="hypothetical protein"
     gene            5900..8053
                     /locus_tag="LNN49_RS25965"
                     /old_locus_tag="LNN49_25970"
     CDS             5900..8053
                     /locus_tag="LNN49_RS25965"
                     /old_locus_tag="LNN49_25970"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_001235747.1"
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPEYKAWKVETLPLRLYPVKYQPVESAAKQVKTILELIRRGDVTEIVHAGD
                     PDDEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKALARS
                     VADAVYGFSMTRAYTIPAKARGYQGVLSVGRVQTPVLGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVIRANWKPGEFAPLTDRKLLDKAWADGTAASLAGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKMTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFPQSLDIDSARKSKAFNSAKVTAHTAIIPTASVPDVNALSTDERNVYLAIAQ
                     HYLVQFMPEKAYQEVSVAIQCGDESFYARARKTTDSGFEAFLGAETTDEGESEDNDDSA
                     FELLCKIRTGETLTTKEVVVNEKKTTPPPLFTEASLLAALVRVADFVTDPTIKKLLKDK
                     DKDKKDEHGGIGTPATRAAILETLKKRNYITLEKGKLIPTDTGYALIDALPGIAVNPDM
                     TALWSEKQTAIENGDLTVEEFINELYGELTGMISDVDLGEMKIEPAAPAGQFQRLDSPC
                     PSCGKHIVIRPKGYFCTGCEFKIWSEFSGKKITQAQAEKLVKSGKTDLIKGFKKKSGGT
                     YDTVLVLEDKKTGKLGFPVRAKK"
                     /name="type IA DNA topoisomerase"
     gene            8050..8256
                     /gene="hha"
                     /locus_tag="LNN49_RS25970"
                     /old_locus_tag="LNN49_25975"
     CDS             8050..8256
                     /gene="hha"
                     /locus_tag="LNN49_RS25970"
                     /old_locus_tag="LNN49_25975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_000850859.1"
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
                     /name="hha"
     gene            8272..8736
                     /locus_tag="LNN49_RS25975"
                     /old_locus_tag="LNN49_25980"
     CDS             8272..8736
                     /locus_tag="LNN49_RS25975"
                     /old_locus_tag="LNN49_25980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293133.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0030527 - structural constituent of chromatin [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_001293133.1"
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFAREIDFEQLLEMQEKLNVV
                     IEERREDAEREAAERQELEAKRQQAIEYIISLGLDPESLLAPVTADTVKTRRKAKGGVR
                     KAKYRFKDENGEIREWSGNGKRPLALQKLLDEGHFMEDFLIDKLQPGQVE"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            8840..9496
                     /locus_tag="LNN49_RS25980"
                     /old_locus_tag="LNN49_25985"
     CDS             8840..9496
                     /locus_tag="LNN49_RS25980"
                     /old_locus_tag="LNN49_25985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001478769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000972911.1"
                     /translation="MMIKSKKVVVIFVALSSFLLAGCDSPKDANKQNFEKAINTRLEKE
                     CITISPLGMFDSKPYPVQIAVAQANRYTSQERADEINSRQFSALDVLVKADLLTVKNTL
                     VDDVIGFTKTGKKVPGREYALTDEGKKYLKSPERPDFCVGHYKVDEIVDFTEPGDAMGM
                     KITQVNYTFSPTSIAEWAKRDDVRAAFLGLESDLKEKQTKHITLVLKNDGWSAER"
                     /name="hypothetical protein"
     gene            9579..9968
                     /locus_tag="LNN49_RS25985"
                     /old_locus_tag="LNN49_25990"
     CDS             9579..9968
                     /locus_tag="LNN49_RS25985"
                     /old_locus_tag="LNN49_25990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_236115859.1"
                     /translation="MTLSKILTDIFRTANNLTHCKTTNQLLAGDASSTLASAILSCDRY
                     SIFEQDYPRSSLIRQAVRHTGHSVQTSLVTTFKYSVPLSGALFRHMCPYPGLFRITASF
                     SPCPVVHIHLDKNALSEKMSKFFFW"
                     /name="hypothetical protein"
     gene            10053..10877
                     /locus_tag="LNN49_RS25990"
                     /old_locus_tag="LNN49_25995"
     CDS             10053..10877
                     /locus_tag="LNN49_RS25990"
                     /old_locus_tag="LNN49_25995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001487124.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA];
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_016238959.1"
                     /translation="MSDLPASIFQISRSDAWNLTISPDAARNMRDLASQIGAGMPKYLI
                     APEVSLLLSYIDDLNIRMYFETLWNTGARLNEALALKPADFMLTPTRQYPQPVVILKTL
                     KQRLKEAERRPGRPTTRHPPLHPDPRYRKPPEPAVRLVPVLDAGYALRMREYLATWKKR
                     IKHQPVWDITSRQTPLNWINTAVARAERDGVTFSVPVTPHTFRHSYAMHLTMSGVPPRV
                     LQSLLGHRYARSTEIYTRVFSLDVLTGSGLSFTCDPQLAKQLLGYPERLNNE"
                     /name="tyrosine-type recombinase/integrase"
     gene            10982..11641
                     /locus_tag="LNN49_RS25995"
                     /old_locus_tag="LNN49_26000"
     CDS             10982..11641
                     /locus_tag="LNN49_RS25995"
                     /old_locus_tag="LNN49_26000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000516230.1"
                     /translation="MGKIITVAGHKGGIGKSTVLCSLCVCVIKKGKTACFLETDSQGSI
                     KDFIEDRKTNARLSEIPYFECYTDIPAMAQKLAARFDYVFVDTPGMKSPAFVKALSCAH
                     ILFTFIEPGSGIEINTLGRLVFDIKTAQAGVNPSMKAWIVLNKCSTNPSDSEASELRRQ
                     LNDDPDWLPVPRQRIYMRTAHKKAYNNGMGVHEYDDKRGNKARGEIELLLKETDIL"
                     /name="division plane positioning ATPase MipZ"
     gene            11807..12109
                     /locus_tag="LNN49_RS26000"
                     /old_locus_tag="LNN49_26005"
     CDS             11807..12109
                     /locus_tag="LNN49_RS26000"
                     /old_locus_tag="LNN49_26005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001062964.1"
                     /translation="MAKIPKKIDQEIKPLDLRQFVSSAAQKPASASAVTRINLTMTDDD
                     LDTAQVFQNKYGASRAEVIRAALAALRLVSAEERRRLFDDIRKNSPKAGRPTVNK"
                     /name="hypothetical protein"
     gene            12146..12397
                     /locus_tag="LNN49_RS26005"
                     /old_locus_tag="LNN49_26010"
     CDS             12146..12397
                     /locus_tag="LNN49_RS26005"
                     /old_locus_tag="LNN49_26010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001482241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000905709.1"
                     /translation="MLIKIIKSVFNFYMLCVQPFIGLVLAGYGAWKFSGDSISALLEPA
                     SYFVIGTVVLFVWYIAWQKERSKEEEFKSSIKPEDFVK"
                     /name="hypothetical protein"
     gene            12447..12662
                     /locus_tag="LNN49_RS26480"
     CDS             12447..12662
                     /locus_tag="LNN49_RS26480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000399458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000399460.1"
                     /translation="MEHCIFDLGIINYHPVITWTVPVAFFFLVLLAGIVFNIGRKSNLI
                     VFILAMLLPVTTVFIFMLLGGKIDMC"
                     /name="hypothetical protein"
     gene            complement(12969..13496)
                     /locus_tag="LNN49_RS26010"
                     /old_locus_tag="LNN49_26015"
     CDS             complement(12969..13496)
                     /locus_tag="LNN49_RS26010"
                     /old_locus_tag="LNN49_26015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="WP_000577047.1"
                     /translation="MIFNRNKKRDEQQNSSVVLPSTENVFSDFIKNNPALTTNAFTAIG
                     EVDCFTKVPLLSNKESEFLGILSRNIIPDYSVFPKIRLIEFVRPHGSEEAVKELIREVQ
                     NITCDFVLKSYDETVLAVIQFGETATVRQQKKKLIIQRVCAMTEISFFEFKNTVDMMGS
                     EDFCQFLRDDEE"
                     /name="DUF2726 domain-containing protein"
     gene            complement(13632..14036)
                     /locus_tag="LNN49_RS26015"
                     /old_locus_tag="LNN49_26020"
     CDS             complement(13632..14036)
                     /locus_tag="LNN49_RS26015"
                     /old_locus_tag="LNN49_26020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000654313.1"
                     /translation="MKDNIVDFQRIRRDLGAHSTDVANDAVYSDKKKTSRFFYLLTPVR
                     YLLAASLYLVVVIPLGILAGFRFLLQFLGGIAVMGLTIAWYMGADVSGYIVLAAWIALT
                     VCGCAEQIFEWWIESRFAFRLFGIGRTPEE"
                     /name="hypothetical protein"
     gene            complement(14102..15109)
                     /locus_tag="LNN49_RS26020"
                     /old_locus_tag="LNN49_26025"
     CDS             complement(14102..15109)
                     /locus_tag="LNN49_RS26020"
                     /old_locus_tag="LNN49_26025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243325.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000243324.1"
                     /translation="MVLKNNKNSDCNDVQSLLAQGNQLLEGAYDITLIEMRLLYLALTK
                     IDSRKPQPANEYTLFAKEYRDTFSLDSKNCYEQLKSAASSLGSKPIVTYEWNEAKKRID
                     AVKRFWFSSIRYGVGNSESDITLRFSDSVSQYLYELKSEFTQMNLEHMVKLDTPFSFRL
                     YSWLYKYKNLNRNKKHSGVISTDPITIEWMKERTGLTGKYPVYKDFKKRVLDPAVDIIN
                     ANTNLSVTYEGIKSGRKIESVVFTYLVENETHDGKKIATKPLRPRLPSRPRVIKGSSAE
                     VAWAKKCIDVMKNYLISLREYDDKLKLSRPDLQKVKLWHEITGWDFEESFWFSD"
                     /name="replication initiation protein"
     gene            16653..16988
                     /locus_tag="LNN49_RS26025"
                     /old_locus_tag="LNN49_26030"
     CDS             16653..16988
                     /locus_tag="LNN49_RS26025"
                     /old_locus_tag="LNN49_26030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004026069.1"
                     /GO_function="GO:0004540 - RNA nuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0008219 - cell death [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001147119.1"
                     /translation="MPYTAKRYQTENGEVPYTDWMKKLRRKDQTAALKVDSRIARAMGG
                     NFGDHKFERDGVWELRVDYGPGYRVYYSIEDGEIILLLIGGNKKTQTADLDKAVSYLQD
                     FKKRSKK"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            16985..17335
                     /locus_tag="LNN49_RS26030"
                     /old_locus_tag="LNN49_26035"
     CDS             16985..17335
                     /locus_tag="LNN49_RS26030"
                     /old_locus_tag="LNN49_26035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000127483.1"
                     /translation="MTATKNVKSQKNDYSASVDHNAAMIEELRADPDYANAYLANALEE
                     INEPGGLGGFLVALRQVIEARGGISEAARKSGLARQSIYRALSPNGNPTITTLAQLTSV
                     AGLQFTLSKSSH"
                     /name="hypothetical protein"
     gene            17974..18489
                     /locus_tag="LNN49_RS26035"
                     /old_locus_tag="LNN49_26040"
     CDS             17974..18489
                     /locus_tag="LNN49_RS26035"
                     /old_locus_tag="LNN49_26040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025396.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025396.1"
                     /translation="MNIQEALNVFGLSGELTEKDIKAAYRKAALKYHPDRNPLGAELMK
                     AVNAAFDVLMANIDKINQFQSTDEHARYNYGDDLEKVLNVLSGLSGLVFEVIGNWVWIS
                     GETITHKETLKEIGCKWAAKKKQWFYRPDEHKSYWNREEHTIEEIRAKYGTTGQRRATG
                     WQRVETRV"
                     /name="J domain-containing protein"
     gene            18594..19136
                     /locus_tag="LNN49_RS26040"
                     /old_locus_tag="LNN49_26045"
     CDS             18594..19136
                     /locus_tag="LNN49_RS26040"
                     /old_locus_tag="LNN49_26045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001083908.1"
                     /translation="MNSFFEQYHPVFEVVCRILGNGWRVNKLDDCSSRIKLTSPQFKNY
                     SVHIRMEKDRFSVVGSVDSRSWRSPHHVCTLSRKRNPVDIAADIERKILVNASQEVLQA
                     IEYEKHQVEKKDEIMILKGMLSQLVQLESWYGALTGFKAENGLNGKVTEQGDSYDLQIR
                     GLSIDQLVKITGYLKQL"
                     /name="hypothetical protein"
     gene            19133..19384
                     /locus_tag="LNN49_RS26045"
                     /old_locus_tag="LNN49_26050"
     CDS             19133..19384
                     /locus_tag="LNN49_RS26045"
                     /old_locus_tag="LNN49_26050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001565860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001230708.1"
                     /translation="MRKNKGDVTYFLEKEGDNYRLTKRIKARTNVKIGNKTTKITLYDA
                     VLNENELQHIDFTCAGLRKDDETPVKNLIKEFMLNETR"
                     /name="hypothetical protein"
     gene            19371..19598
                     /locus_tag="LNN49_RS26050"
                     /old_locus_tag="LNN49_26055"
     CDS             19371..19598
                     /locus_tag="LNN49_RS26050"
                     /old_locus_tag="LNN49_26055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000801440.1"
                     /translation="MKPDNTPENVKKLRLKAGLTQKECSHIYGVGLRTWQKKEEVNTQN
                     SQSLSLVEFEFLLLLAGEHPEYVLCKRESK"
                     /name="hypothetical protein"
     gene            19990..20289
                     /locus_tag="LNN49_RS26055"
                     /old_locus_tag="LNN49_26060"
     CDS             19990..20289
                     /locus_tag="LNN49_RS26055"
                     /old_locus_tag="LNN49_26060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000650313.1"
                     /translation="MKCSSVFTSTTNHVFTFERVTLCTIILMHKDTGQQYVVLFTDNNK
                     IRDYKTGIVPQFGELKQSDVDLVLFYRDEYEKYFDSLKDGDECLSFKDFIECLR"
                     /name="hypothetical protein"
     gene            20381..20746
                     /locus_tag="LNN49_RS26060"
                     /old_locus_tag="LNN49_26065"
     CDS             20381..20746
                     /locus_tag="LNN49_RS26060"
                     /old_locus_tag="LNN49_26065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000854262.1"
                     /translation="MKTLKQAAMQFASDLRNNRCFKAAYNDALLELDREDLNAIVQCTF
                     LFEPKRTLAELDKLIKKIEVEEDYEFCVSLDKGNGLHEVRTFKSEREALDAYRILTLYG
                     YTVTIEKKEGNDWLFKV"
                     /name="hypothetical protein"
     gene            <20997..21194
                     /locus_tag="LNN49_RS26065"
                     /old_locus_tag="LNN49_26070"
                     /pseudo=""
     CDS             <20997..21194
                     /locus_tag="LNN49_RS26065"
                     /old_locus_tag="LNN49_26070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681609.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /name="type II toxin-antitoxin system HicB family
                     antitoxin"
     gene            21557..22060
                     /gene="ddp1"
                     /locus_tag="LNN49_RS26070"
                     /old_locus_tag="LNN49_26075"
     CDS             21557..22060
                     /gene="ddp1"
                     /locus_tag="LNN49_RS26070"
                     /old_locus_tag="LNN49_26075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 1"
                     /protein_id="WP_000781818.1"
                     /translation="MKMIAFRLSDDELKLAEHNAISSGFTSINTFARHNVLNVDVQPSN
                     IPVSNESSKAVKTCLYPHEIELVKRNAALHGMSMSREIAIRVRQSLLKNEVCLYPDEVK
                     ELKKLSTAVDRVGRNIHFIIKGERFCTVNDPDFRKDVVEVIELCKQIDSKLETLTKSVV
                     NRFG"
                     /name="ddp1"
     gene            22064..23293
                     /gene="taxC"
                     /locus_tag="LNN49_RS26075"
                     /old_locus_tag="LNN49_26080"
     CDS             22064..23293
                     /gene="taxC"
                     /locus_tag="LNN49_RS26075"
                     /old_locus_tag="LNN49_26080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA relaxase/nickase TaxC"
                     /protein_id="WP_000539545.1"
                     /translation="MGVYVEQEYRIKRAKGTGRDPKSPKLSGRHIHASKSAFNHKVRHG
                     TDKKAYTWTPTKEVTFKITGSGKTAAGIKNGIDYITRNGELEAYCYDGKGSEQTGKGED
                     FNREFTSTLSKGNDYSRTYRGENIDHVKNMVFSPPPEAGVSREDALKATIEFLKETYPN
                     HAFVAVYHDDKEDHPHVHVNIKLRDEETGRRLRLTKSETRKFRNGFHRKLKGMGYDVTA
                     TWKKDPERKREIERLQAENPKRLRNVYKVVDFGETSYQNKAGEKRTPFLTYETLKGGKQ
                     VTIWGKDLKNHFESEKLQPGTLIKVKKLAPTLVRSPMFNDDGTVAGYRETHRNNWQIEN
                     IALERNRERQVHERETRQPEESDVKKQLSRKHEQGHNIGFALEHGFTKDSEEHKKLRIQ
                     QERNWKGLGF"
                     /name="taxC"
     gene            23370..23663
                     /locus_tag="LNN49_RS26080"
                     /old_locus_tag="LNN49_26085"
     CDS             23370..23663
                     /locus_tag="LNN49_RS26080"
                     /old_locus_tag="LNN49_26085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134733.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO:0016987 - sigma factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_000134733.1"
                     /translation="MTEHDAICISALHQIFSDEEHLSEQQKDIILMYAYGYTLNEIADF
                     KGLKPSTVRKYLDSVRAELGGVSLAGIRTLVLIRTNALLVSSLSRISERGNL"
                     /name="sigma factor-like helix-turn-helix DNA-binding
                     protein"
     gene            23660..23875
                     /locus_tag="LNN49_RS26085"
                     /old_locus_tag="LNN49_26090"
     CDS             23660..23875
                     /locus_tag="LNN49_RS26085"
                     /old_locus_tag="LNN49_26090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000760375.1"
                     /translation="MKKYLLFALPFFVVGCSEEVKSVDWWGQHLTEAKQKQAECEKSGS
                     DSQNCKNVKQALFIQSQKDAPVPTFD"
                     /name="EexN family lipoprotein"
     gene            24052..24228
                     /locus_tag="LNN49_RS26090"
                     /old_locus_tag="LNN49_26095"
     CDS             24052..24228
                     /locus_tag="LNN49_RS26090"
                     /old_locus_tag="LNN49_26095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000660496.1"
                     /translation="MKEKPDKSSEKGVYVTIKLDPRLNAFIEEKTKTSLLSKRKQIIYL
                     LMQSMRIDGYMER"
                     /name="hypothetical protein"
     gene            24231..24851
                     /locus_tag="LNN49_RS26095"
                     /old_locus_tag="LNN49_26100"
     CDS             24231..24851
                     /locus_tag="LNN49_RS26095"
                     /old_locus_tag="LNN49_26100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_111530677.1"
                     /translation="MASLFPALLLCAASVHPDTINDIARVESGFNPYAVAEIIPERERG
                     SYGKSVISHMPKSKEEALTVIREIENRKRRYSVGLMQITNSNFSFYSTSAEKLLDPCEN
                     LSVFEKIIVDCYKRGRGLENALSCYYTGNFSNGKRKEKEFNNTSYVERIGYTGNEKKYV
                     VPGTRSNGGEQRKNRSHNASVIWPETILKSAFVDNSHPTKVIN"
                     /name="lytic transglycosylase domain-containing protein"
     gene            24865..25191
                     /locus_tag="LNN49_RS26100"
                     /old_locus_tag="LNN49_26105"
     CDS             24865..25191
                     /locus_tag="LNN49_RS26100"
                     /old_locus_tag="LNN49_26105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000008647.1"
                     /translation="MSFKKSVCNRISSSVTAVMQRKNKVVMAVAGATVASPAFADGFSK
                     AETLLEKVKTGLSGLSLVTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAEVAS
                     MMVN"
                     /name="TrbC/VirB2 family protein"
     gene            25210..27957
                     /locus_tag="LNN49_RS26105"
                     /old_locus_tag="LNN49_26110"
     CDS             25210..27957
                     /locus_tag="LNN49_RS26105"
                     /old_locus_tag="LNN49_26110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="WP_000105985.1"
                     /translation="MSTLYKAMTRPAMYVGVPVVPLTVVAGALFLAGVYISKLIWLAIP
                     VAVFVLRMITKQDDHIFNLYFLKLKMLGNSVCNRFFGARAFLSGQYEAVEIDEFVNAMK
                     LNERITTGKYIPYSSHVDKNIVKTKNGDYVATWQLMGINFESISAEMLETIDSQVATLV
                     RSFSGLPVSFYNHSCRASFYDAFTTKSGNKYADIISDCYYGSMKKNKFKGNTLYFTLIY
                     RPDGRVEKLEKRKKSIKEKKDDINIHVKRMNEMINTFSGALDKFTCKLLGMYEENGKVF
                     SSQLSFYNYLLTGKLQKIRVTDSPVYNVLGGVDVFFNHDTGQICRIDGNKFFRSIEIKD
                     FCSETASGVFDVLQYSDADYIITHSYTSMSKSEALSTIKRAEKQLKSTEDDAVTQLQEL
                     EKAKNDIVSGDISFGYYHFTLMVMADSIRELDESVSKITADFTDLGIIPALSTMSLPAA
                     YFAQLPAVFHLRPRLSPVSNVNFVELASFHNFYQGKRDKNCWTEAVAILKTPSKQAYYL
                     NLHNSVLFKDETGEKNLANTKVIGTAGSGKTMFLSYLACSLQKYNNPETFADSAKNKKL
                     TCVFLDKDRGAELCIRMLGGEYYTVKSGEPTGWNPFALEATKRNRIFVKQLMEILCTRN
                     GERLSTRERLLISESVDAVMDFPPGEMREYGITRMLEHLMQRDDRDEQENGIILRLSQW
                     ANGQAHGWVFDNAKDTFNIQHVNNFGIDGTEFLDDPMVCAPITFYLLYRITQLLDGRRL
                     VIFLDEFWKWLQDEAFSDFVYNKLKTIRKLNGLVIPATQSPDEILKNKISRAVVEVCST
                     SIYLANPDADYNDYVEGLKLTPEEFNIVKNLDPMSRQFLIKKSSLKKGDGKSFSALATL
                     DLSGLGGYLKILSASADNLEIFESIYHEGMEPDDWVPEYLERAI"
                     /name="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
     gene            27969..28685
                     /locus_tag="LNN49_RS26110"
                     /old_locus_tag="LNN49_26115"
     CDS             27969..28685
                     /locus_tag="LNN49_RS26110"
                     /old_locus_tag="LNN49_26115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000832280.1"
                     /translation="MKRVKTFMLISLLTASFYSSAGIPVAIDASPEWAVEAARWTERLK
                     QWSETAQHYQSQIQAYKDQLATATGIRNIAAFTNELSNLQSELTNIYKQGNSYISDFTS
                     NPEGALSSQAKNLFSKYGAFDMCNTGYERNDNLCKARIVSTAASIEQGNEINKQLSNAM
                     SQIQSLSSRIEASKDIKESQDLANALQAQSLKMQAIKMQYDVWNNKNKADHEMLITQEQ
                     EAFIKQQKEAEPLTFD"
                     /name="type IV secretion system protein"
     gene            28697..29791
                     /locus_tag="LNN49_RS26115"
                     /old_locus_tag="LNN49_26120"
     CDS             28697..29791
                     /locus_tag="LNN49_RS26115"
                     /old_locus_tag="LNN49_26120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001677777.1"
                     /GO_process="GO:0030255 - protein secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000046889.1"
                     /translation="MAQGFFVKYNSTVMDSVDKISSSYQTQFANDIMSLATVSVTLYVL
                     WKGYQILASKTQTPLQDLVWDLSKFAIIIMFITNADGYLTAATDALQGMKDGFSGGVSV
                     WQTLDNLWKSTQNLGAEIYSLDKSTYVKDQGVVGQFLIWTGSLILMAVSVVVFLTADVT
                     MKLLIITAPIFIFCLMFGFIRSMFNNWLQSLFSSILTVLFASLVIRIAMDFQGMILSHA
                     IRAAQTGNVNLVSTGAMGFMAGFLGALLVLIAKGFAVQLAGAGVEGAVQGAAMMGLGAA
                     GMATGKSLMLGGRAGLGFGLGMAGRTGMNSLSGKAGNLMGRGARTAAEWAGEKGYQALA
                     PTGALGMKARRLASLEKARARNAA"
                     /name="type IV secretion system protein"
     gene            30306..30992
                     /locus_tag="LNN49_RS26120"
                     /old_locus_tag="LNN49_26125"
     CDS             30306..30992
                     /locus_tag="LNN49_RS26120"
                     /old_locus_tag="LNN49_26125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001290765.1"
                     /translation="MSEKIEKKIETAKSFERQLYAENERSKKNAWRVAVAASLLSLCLG
                     AAICVLVPLKEKELAIVAVGEKTGRTELITQVKQEKILQSEALGRYFVNTYITLREGYN
                     YPSLQYDYETVQLYSSNTVKDDYLRLYNSDMAPDKIYHNNGSYVAVEVISNIISDATAP
                     DKLASVRFKKTTRNFTTGQVSVSYWTARVTYRFEPEKSVKSSSRELNPLGFTVTSYQTD
                     REVRGE"
                     /name="type IV secretion system protein"
     gene            30989..31897
                     /gene="virB9"
                     /locus_tag="LNN49_RS26125"
                     /old_locus_tag="LNN49_26130"
     CDS             30989..31897
                     /gene="virB9"
                     /locus_tag="LNN49_RS26125"
                     /old_locus_tag="LNN49_26130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_001299943.1"
                     /translation="MMKKLFIATCLLLPGLVYSAATPLPSGFDARMQTVSYNGANTTVI
                     RSKTGFLTSVVFDEGEAVISAKAGFPAGWEITTDDNVVYINPRPVVQEQEGDEGEKLKK
                     VFQPTEKEWDTNLFVRTTKRIYSLDLILLSEEKQAQPAYVVQFRYPSEIAKKNAEEVRL
                     AKEKQEKLRQKKLISESFEKADAPKNWDYFMRVNEKYDSRRIAPDFAYDNGIFTFLGFN
                     SGKVFPAPFAVRDGQEQTLAFNVETKGKYKIMVIHNVNDKFVLRYGNSVVGVVNKSFGK
                     VLTDQRNTSSPAVERVEVNND"
                     /name="virB9"
     gene            31890..33008
                     /gene="virB10"
                     /locus_tag="LNN49_RS26130"
                     /old_locus_tag="LNN49_26135"
     CDS             31890..33008
                     /gene="virB10"
                     /locus_tag="LNN49_RS26130"
                     /old_locus_tag="LNN49_26135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_000131271.1"
                     /translation="MTDMKKTDDLVDDANQSKLESKPVHDIGDIRNKNNRMRSGFLFGL
                     MAVLVIGIFALKTYKNYFADDQQKASESTGDTSISQVSKIRTGLGQNFDPVENKAIINP
                     GATGSGNTVSDGHKEVPQEGFRKYLSIPVAGQGGSQTGASGSSRTSQTSEPQEERKESK
                     ENVPGKSGMKVTAINLDPDLYIEENRLIPCALTTRFVSDVAGRISCVFTEDVWSANHHT
                     KLLEQGTKAFGRYQTGTLNHGQGRMFVMWEQLRTPDNKRIDMVNTAAAGPLGEAGIDGW
                     IDSHFWERFGGSLMLSMVQDVAAAAADNAPGKDRNVDYTENSRQAMAEMAKVALENSIN
                     IPPTMYKNQGDIITIMVGEDIDFSDIYELKVK"
                     /name="virB10"
     Typing          complement(14103..15109)
                     /name="IncX4"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.802"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          22065..23290
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          200..2058
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.839"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          28698..29767
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.72"
                     /coverage="100.0"
                     /evalue="6.640000000000001e-173"
     Typing          30307..30989
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.4399999999999998e-137"
     Typing          30990..31894
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tgacgtccat tcacgcggcc tcggcaaaag atgccatcat tcagatggtg acaaaatgtt
       61 atcagaacag agaatgtcaa aatcttcctt ttgatgttct tcgtaaaatc attatggaca
      121 gtattgatat tgttgttcat gtaggcaggg atggtgttgt caggcatatg agcgacatct
      181 attacaaagg ggctgaatgt gaaaactttt aataagtcgc aatctgtttt tatattcgct
      241 gttatgcttg ttgcggcatg gtttgcaggt tcatttattt tctttgtgct ttacttcagc
      301 cagataaaga atctgaaacc attgaaggct gtgttcagat ccattgatgc gtacaggatg
      361 gatattttta cagacagcct tactttatct gttgtgacta cggatatcag agttttagcc
      421 tttgttgcac ttggagcagg atttgtcgtg tctcttatta tccctgttgc ggcgttgata
      481 aaactgaacg agaagaaaga taatattttt ggtgatgcgc gatttgcgac aactaatgat
      541 attcgtgagt ctaacagttt cacgcttgac ggtgacgaaa aagacgggat tatcgttggt
      601 ataaaagaca agaaaatcat acgctatgtg ggagcagcat tcagtgcgat gggagccgga
      661 acaagggctg gtaaaggtgc aggtatagtc atcactaatc ttatgaagta ctggtggagt
      721 gttattattc tcgatccaaa aagggagtgt tttaatatca ccagtcttat caggaaggtg
      781 attttaggtc atgaggttta taaatttgat ccctttagtc cggtaacgca ccgctttaac
      841 cctttgtatt atgtcagcat gggaacgagt gaaggtttta atcagcttga aaatcttgcg
      901 ttgattattt acccctataa gacagatggt gcggatgctg gtagctatct taataagacg
      961 gcggggggtg tttttaaatc ttatgctgtc gctttatggt ttatgattaa gaatgataag
     1021 gctggactaa aaacgcttga tattgagcct gtcttctcaa tgtctaaaat taatcagctt
     1081 tttgagcgtg cagaacccga acatcttctt tcattcatga atgatattcg ttcagaatta
     1141 agggggaaag acaaaacgct tgctgatatt ggtgtcgctg gccttaaggc attcattgag
     1201 atggaggata aaacaaaagc acaactcaaa agcaactttc ttaatggatt atcaccgttt
     1261 gctaacccca atgtggcaaa tgctactgat ggaaatgatt ttgatttgcg gcaggtgcgg
     1321 aaaaagcgga tgacaattta tttctgtatt tctggtgata atgccaggtt ggctgaaaaa
     1381 ataacaaata ttttctttca gcttgctata caggtgaatc ttgaaaagat gccaacggat
     1441 gatccggaaa taaaacatga ctgccttttt ctactggatg aattcccgtc aattggtgct
     1501 gtagattaca tcaagagtaa atctggactc attgctggtt acaagctgaa attgttgatt
     1561 gtttaccagg tcggctctca gcttgaggaa atctacagtt atgcaggcag taaaacatta
     1621 ctggcaagtg caccctgtaa aatcgtttat tccgcttctg atgttaaaga tgcgcgggag
     1681 ttatcagaag cgatgggaac acgaacagta actatcggtt cgaaaagcaa aagtcgtagt
     1741 cgtggaggaa catcgagatc tgaatcagaa agccttattg agcgtccact ggtaacaaca
     1801 aatgaactac ttacactgaa atttagtgaa gaaatcctgg caatgaaggg agaaaacccg
     1861 attcgttgtg aaaaggcatt ctactatctc catgagtatt tctttggtga ttttgtgaag
     1921 gttgctccgg aacttgcaaa cattttcccc aggaagaaag gaaagttggt tatgcctcca
     1981 cagaaagtat ttgaaaatga aatcgtcgca aaagggtatc tggcagtaaa agaagttcct
     2041 gatctcgata aagcggcata aaggagaaca tgatgaagaa gttagtgttt ttattgattt
     2101 ctatccttgc tggttgttca tcaccgccag agccaacacc cgtgcagttt gaaaaggcaa
     2161 atgaagtgat caatccctca ttgccatatg tccccgattt tcacggtgtc ataaagtcag
     2221 acgttagcgg taaaggatgg gtttatgaga tcacttcctt atccggagta caggccagaa
     2281 cgccgacgtt ttattacgct ctggctcatg cggacaggat tgtagtgaca acacatgatg
     2341 ctgggctgtg gtttcgaatc agagatctgt tgaagatgga aggggcaaca gcagtcgtgg
     2401 agtggcgaaa cgagaaaagt tttttacctg aacagggaaa aatagttttc attaaagcac
     2461 aaaacgaggt gaaaaatgac tggaaaaaat agagtggttt tacctgcctt gctggcgtta
     2521 ggattaatat caacaaatgc taatgcatct gatccttgcg cttcggtact ttgcttatat
     2581 ggaaaagcag tcgggcaagg tggagggagt gagtgcagaa gtgctgaaaa ggattttttt
     2641 aatattctga aaaagaaaaa aggaagcatt cgctggagta aaacatttga tgcccgtaaa
     2701 gcatttctga atcagtgttc aacggctgat ccggctgcta tctcaaaaat tatgagtaag
     2761 ttcggacgcg ttaagggctg attaaaacct gatacccgcg ccaacgggta tcagtggaca
     2821 tacaggagaa aaattatgag cgaaatccga tttgtaactc tggaatccga ctttaacaat
     2881 attaaagaaa tttattctga tgatgagtta aaccgtttgc tggaagctgt taatcagaat
     2941 tgcccgacca gaattgtgtt gggtagcgtg gagaagggga aagaaacacc actcaagtgg
     3001 tgttttagaa caataccaga gcgtatttca attgaggaaa tcgatgaaat aaaatttatc
     3061 cagaatcctt ctgaacaggg ataaaggtaa acgccgcaga ttccagattt taatctggga
     3121 tttgcggggt tgaacaaccg aagggcgtta gtttcccgtt atccatgagg tatatatgaa
     3181 agcaagaagt gtgagagttg ccggaattga aattatcgat agtgttaaaa cggtcgctta
     3241 tgtttttact gaggccttac tgtttatggt ctggttttcg gcaattgtct atgggcttta
     3301 tcgtgttgtt atcgttttat gggatgatcc tttaaagccg caatcgctca tggaatttct
     3361 taatttcata gttgagttgt atagctatgt acttccttcg ttggctgtta tcgcagtggc
     3421 tttaatcgcc gttttatcca tttgtaaaat actctcagca atatgggagg gaagaaagca
     3481 atgagacatt ttcttaaggc tctttccttt gttgtttccc tgttaccagc tacattgtgt
     3541 gcggctgaaa tccaggggaa agttattcgc gttctcgatg gcgacaccat agaagttaaa
     3601 acactacccg cgaaaattgt tgtgtatgaa gttccgatca gggttcgatt gataaatatc
     3661 gatgctcctg aaaagaaaca ggctttcggg cactggtcag caaatcagct taaagctctg
     3721 ctcgcaggac aatcagttac cgtctcttat acgcagacag accgctacgg acgcattatc
     3781 ggtcgtgtgt tcacgacgaa cggcacggat gccagccgct ttatggttca gtctggcgct
     3841 gcatgggtat atgaacgtta caacacagat aaatcattac cggctttgca acgggaagcg
     3901 caggaacaaa agcgtggttt atgggctgac agtaatccgg ttccaccgtg ggaatggcga
     3961 cataaacaga actgacgcgc gttgcttgtc caacccctcc actaccttaa ataaatttca
     4021 ggcagtgtca cggttttaaa tatacatggt gcgcttatgg gtaaattaac tctggtagag
     4081 caggctttac ggcttcacaa agaatattac ggtgaagata attttggaac tgtcgtaaag
     4141 gattgtgatt actatcctaa agtggcagag atttttataa acagaaagaa ccgtaaaatt
     4201 tattcgaatc tggatatcga acctgttgct tcaaccgttg ttcatacggg aagtaaccct
     4261 gttatggcta aagctgggag aattaaaaaa cttatgttca aagatggttc tggtgcatac
     4321 aggattcatc ttggtcaaaa tgaagttgtt catattattc gcttcattct taactctaaa
     4381 gtcaggatgg agtacgccgt tgggactact aaaagtatgt caatgctcca caatctttgc
     4441 gaggcaggac gcgctaaatt aaaccgctca ttgccacgta aaggtatctg gaaacttggg
     4501 tactatgatg gtgtttatta tcacggtaag gcaagaaagg aggaaattga aaatgctatg
     4561 cgtttctcag ttcatccaaa atttgacgag ctggaaaacg actttaatca gttcttttct
     4621 gatattgatt tctatacccg gtatggtcag tcaggtatgc gtaaagtgct ctttactggc
     4681 ccccctggaa caggcaagac aactatcgca aaagctttgg gggcaaagta tcaggataag
     4741 tatgtttttg tttatgccga tgattacttt aaagatgttt gctacgctgc tgctcagaag
     4801 aaaatacccg tcattattat agctgaagag gttgatgaac tttatcgggc tgatgccgga
     4861 acgttaagtt ttcttgatgg agctgataca ccgcgaaatg tcgcaggtac atatgtgatc
     4921 ttttctacaa actatccaaa acgcatcgac ccacgtatta ggaaacgtcc aggtcgaatt
     4981 gacaggataa tctctgtagg tgctttcaga accaaagctg ctgccgcttg cgccaaaatg
     5041 tacttaccag aagatgtaga aattgacctt aaagagcttg gcgcagtgct ggacagaacg
     5101 actccggctg aaatcaagga aattattaat atcgcaatcg gaatgattcg cggaaccaaa
     5161 aatgaattat cagtggatgt aataaaaaat gctcgtgcct ttttgaaagg aacccttgat
     5221 ctgagcgtgc aggaagcaga tgaagatata gaggaaaggg aagagcttta taaaaagaac
     5281 ggggcgcaac ctgactattt aagttacctg gaggattaac acatgcaata tgcattagtt
     5341 gatgcgctgg aacgaaaatt tttgctggat gctcttgaat ttggtgttct gaaggactgg
     5401 aaagaaaatc cggtaaaaga acttcctgat attgatgaat ctgttcaccc cttccatatc
     5461 tgttatggtg gatatttatt aaaccctggt gtttcagatt cagatattag cagaaaaata
     5521 aaagaccagg caggattctg gctggcagct attgatgata cccgcatgga ttgtcattca
     5581 atagcttatt atgatattca cacactccct ctgatttcgt gtggtcatca aaagatagtt
     5641 ccttttgccg cgttaataaa agctgatgaa tgcatcattt caaaaattgc ttcgtattct
     5701 ggttttgctg taacagcctt tttgagaatt aaagagtggg atattgcaac taatatactt
     5761 aaccgtgagg gaatttttgc ctttaatggc tgtgagcgca gattcagagt agtaagtaaa
     5821 gataactggc aacatacagt atcggaagaa cgcgctatcc gttgtgccaa aagattaatt
     5881 caatgtaaag gataacaaaa tgagactttt tatcgcagaa aaacccgcag tagcaaatga
     5941 tattgttaag gcacttggtg gcaattttac ccgccatgat ggctggtttg aaagtgataa
     6001 cgccattgtg actaactgtt ttggtcatat tatcgaatca cagccgccgg aaaactataa
     6061 tcctgaatac aaagcctgga aggttgaaac gcttccttta cgtctttatc ccgtgaagta
     6121 tcagcctgtt gaaagtgcag caaaacaggt taaaacgatt ctcgagctta tcagacgtgg
     6181 agacgtgact gaaattgttc acgctggcga tcctgatgat gagggacagc tacttgttga
     6241 tgaagtcctg gaatatgcag gaaacacaaa acccgtaaag cgcgttctga ttaacgacaa
     6301 cacgcttccg gcagtgaaaa aggcactggc aaatcttaaa gataatcgtg atttcaaagg
     6361 gctttacctt aaggcgctgg cgcgttcagt tgctgatgcc gtctatggct tctccatgac
     6421 gcgtgcttac accattccgg caaaagccag aggatatcag ggtgttctgt ctgtcgggcg
     6481 cgtccagact cccgttcttg gcctgattgt gaatcgtacc cgtgctaacc agaaccataa
     6541 atccagtttt tactacacca tgaccggagt ctttcagcgt ggtgctgatg ttatcagggc
     6601 gaactggaag ccaggggaat ttgctccgct gaccgaccgt aaattacttg ataaagcgtg
     6661 ggcagacgga acggcagcat cccttgcagg aaaaccggct acagttgaag cggcagcaac
     6721 tgatgataaa aaaacggctg caccgttgcc gtttaacctg gtcagactcc agcaatacat
     6781 gaacaaaaag ttcaaaatga cggcacaaaa aacactggat attacgcaac aattacgtga
     6841 aaaatataaa gcgattactt ataaccgctc tgattgctca tatctttctg atgaacaatt
     6901 cagcgaagcg ccgcaggtta tcgatgccct gaaatcagtc tttcctcagt cgctggatat
     6961 tgattctgca cgtaaaagca aagcgtttaa cagtgcaaag gtgactgcgc atactgcaat
     7021 aatcccgacc gccagtgtgc ctgatgttaa cgcactcagc accgatgagc gcaatgttta
     7081 cctggcgatc gcacaacact atcttgttca gttcatgcct gaaaaagcat accaggaagt
     7141 atcggttgcc attcagtgtg gtgatgagtc gttctatgcc cgtgccagaa aaacaactga
     7201 cagcggattt gaggcgtttc ttggcgcgga aaccacagac gaaggtgaat cagaagataa
     7261 tgatgattcc gcttttgaac tgctctgtaa aattcgcaca ggagaaacac tgacgacaaa
     7321 agaagttgtc gttaatgaga agaaaacaac accgccgcca ttatttaccg aagcctcctt
     7381 gcttgctgcg cttgttcgcg tcgcggattt tgtcactgac ccaacgatta agaaattgct
     7441 gaaagataag gataaagaca aaaaagatga acatggtggc attggtacgc cagctacccg
     7501 cgcagccatt ctggaaacac tgaagaaaag aaactatatc acgctggaaa aagggaaact
     7561 tattcctact gataccggat atgcgcttat tgatgccctg cctggtatag cggttaatcc
     7621 tgatatgaca gcattatggt ctgaaaagca gacagccatt gaaaatggcg acctgacggt
     7681 tgaagagttt attaatgagc tgtacggtga actgacaggc atgatttctg atgttgacct
     7741 gggcgagatg aagattgaac ccgctgcgcc agcagggcag tttcaacgcc tggactctcc
     7801 ctgcccttcc tgtggtaaac atattgttat cagaccaaaa ggttatttct gtaccggatg
     7861 tgaatttaaa atctggagtg agttttctgg taagaaaatc acccaggcgc aggcagaaaa
     7921 actggttaaa tcagggaaaa ccgatttgat taagggattt aaaaagaaaa gcggtggaac
     7981 gtatgataca gttcttgttc ttgaggataa gaaaacaggg aagctgggtt ttccggtaag
     8041 ggctaagaag tgaaaacaaa gcaggaatgg ctttttcagt taagaaaatg tacatcaaga
     8101 gatactcttg aaaaagttat tgagattaac cgttacaaac tgcctttatc agaatcagag
     8161 gcattttatt ctgccgcaga tcatcgccgc gcagaactgg tgatgaataa actgtatgat
     8221 aaggttcctt ccggcgtctg gaagtacgtc cactaaacaa gaggattaat tatgagcgaa
     8281 ctgactaaag aagatgaata cggcattatc agccggacta tgatgaatat tcgttcattg
     8341 cgtgtttttg cccgtgagat tgattttgag cagttgctcg aaatgcagga aaagctcaac
     8401 gttgttattg aagaacgtcg tgaagatgct gaacgtgaag cggctgaacg ccaggaactt
     8461 gaagccaaac gtcagcaggc cattgaatac atcatatctt taggtcttga tcccgaatca
     8521 ctccttgctc ctgtaacagc tgatacagtg aaaactaggc ggaaagccaa aggcggagta
     8581 agaaaggcta aataccgctt taaggatgaa aatggcgaga tcagagaatg gtctggtaat
     8641 ggcaagcgtc cgcttgcttt acagaagctg cttgatgagg gccatttcat ggaagatttc
     8701 ctcattgaca aactgcaacc tgggcaggtt gaataaaata atcgtgatgc cgtcgcaaac
     8761 aagtttgcga cggcaaatgg aggggacaga acagccagcg gcgctggcaa gaaattttat
     8821 cgtttgataa agagggaaaa tgatgatcaa atcaaaaaaa gtagtggtta tttttgttgc
     8881 tttgagttca ttcttgctgg cagggtgtga ttcaccaaaa gatgctaata agcaaaactt
     8941 tgaaaaagct attaatactc gactagagaa ggaatgcatt accattagtc cgctgggaat
     9001 gtttgatagt aagccttatc cggttcagat agctgtggct caggctaatc gatacacatc
     9061 tcaggaacgg gcagatgaaa taaattctcg acagttttcc gcgctggatg tactggtcaa
     9121 agccgattta ttgacagtaa aaaataccct ggttgatgac gttattggtt ttactaagac
     9181 gggtaaaaaa gtgccaggtc gtgaatatgc tctgacagat gaggggaaaa aatatctgaa
     9241 gtctccggaa cgacctgatt tttgcgtcgg tcattataag gtggatgaga tagttgattt
     9301 taccgaacct ggtgatgcta tgggaatgaa gatcacgcag gtgaattaca cattcagtcc
     9361 caccagtatc gctgaatggg cgaaacgcga tgatgttcgg gctgcatttt taggacttga
     9421 gtctgatttg aaagagaaac aaacaaaaca tattacactg gttttgaaaa atgatggatg
     9481 gtctgctgaa cggtaggctg taatggtgtt gctacgtgaa aaatacccca cgtatatccc
     9541 ctgctttttc acggatttca cgtagcgcac cgccgttaat gactctatca aaaatactca
     9601 ccgatatttt tcgcactgca aacaacctaa ctcactgtaa aacaacaaat cagcttctcg
     9661 ccggtgacgc atcgagcacg ctggccagcg cgatcctcag ctgcgaccgc tacagtattt
     9721 ttgaacaaga ttaccctcgc tccagtttaa ttcgccaggc agttagacat acaggtcatt
     9781 ctgtccagac ttcattagtt acaacattca aatattctgt tcctttatcc ggtgccctgt
     9841 tccggcatat gtgcccatat cctgggttat tcaggataac cgcttccttt tcgccctgcc
     9901 ctgtcgttca tatccacctg gacaaaaatg cattatcgga aaaaatgtcc aaattttttt
     9961 tttggtgatc ggaatttttg ttgtcggacg cacctctgct tcaggtcata attgctggca
    10021 cgtccagaaa aacaggtgcg gagattaaaa aattgagtga cttacccgcc agcattttcc
    10081 agatttcacg tagcgacgcc tggaatttaa ccatctctcc cgatgcagcc cgtaatatgc
    10141 gggatcttgc atcacagatt ggcgcaggaa tgccaaaata tctgatagca ccggaagtct
    10201 cactgcttct ctcctacatc gatgatctga acatacgtat gtactttgag acgctctgga
    10261 ataccggagc acgactgaac gaagctctgg cgctgaaacc tgccgatttt atgctgactc
    10321 cgacgcggca gtacccgcaa cccgtggtga tcctgaaaac actcaagcaa cgtctaaaag
    10381 aagcagaaag aagaccagga cgtccgacca ccagacatcc accattacat cctgatccgc
    10441 gatacagaaa accaccagag cctgctgtaa ggctggttcc tgttctggat gccggatacg
    10501 cattgcgtat gcgggaatac ctggcgacct ggaaaaagcg gatcaaacat cagcctgtgt
    10561 gggacataac atcgagacag acaccgctga actggataaa caccgcagtg gcacgggcag
    10621 agcgtgacgg cgtaacattt tcggttccgg tcactcctca cacgttccgc cacagctacg
    10681 ccatgcacct gacaatgagt ggcgttcctc cgcgcgtcct gcaatccctg ctgggacacc
    10741 gttatgcaag aagcaccgag atttacaccc gcgttttttc gctggacgtc cttacaggaa
    10801 gtggcctgtc ctttacctgc gatccacagc ttgcaaaaca gcttcttggg taccctgagc
    10861 gccttaataa tgagtaataa tacacaccat taaactattg ccagcacgca attgtacggt
    10921 tatactttca ccacaaaaga ttgtgtatta atacacacta tttaaccagg aggattttgt
    10981 gatgggaaaa atcattacag ttgcaggaca caaaggcggc ataggaaaaa gcaccgtgct
    11041 ttgttcctta tgtgtatgtg tcataaagaa agggaaaaca gcctgtttcc tggaaacaga
    11101 ctcacaggga agtatcaagg atttcatcga ggatcgtaaa accaacgcca gactgtcaga
    11161 aataccgtat ttcgaatgct acacggatat tccggctatg gcacaaaagc tggccgcccg
    11221 ctttgattat gtgtttgttg atacaccagg catgaaatct ccggcgttcg ttaaagctct
    11281 gagttgtgct cacattcttt tcacattcat tgagccagga tcaggcattg agatcaacac
    11341 actgggacgg ctggttttcg acattaaaac agcacaggcc ggagtcaatc cgtcaatgaa
    11401 agcatggatt gtcctgaata agtgctcaac taacccgtca gacagtgaag cgtcagaact
    11461 gcgccgacaa ctcaatgatg atccagactg gcttccggtt ccccgccagc gtatctatat
    11521 gcgtactgcg cataaaaaag cctataacaa cggtatgggc gtacatgaat acgatgataa
    11581 acggggaaac aaagcccgtg gcgagattga gttattgtta aaagaaacgg atattctgta
    11641 atgtgtatta ttacacacca aatttgataa tatacccata tccgatgcga tatacggcgg
    11701 ggatggctta tctgaccaag cctggcaatt tgcagtacgt ggatgccgga actttccctg
    11761 ccataaatga tgtgtatagt tacacacctt ataaaaagga taccttatgg caaagatccc
    11821 aaagaaaata gatcaggaaa ttaaaccact ggatttacgc cagtttgtaa gttctgctgc
    11881 acaaaaacca gcatcggcat ccgcagtaac gcgtataaat ctgactatga cagatgatga
    11941 tctggataca gcgcaggtgt tccagaacaa gtacggtgca agccgtgctg aagtaatcag
    12001 agcagcactg gcagcgttac gtctggtatc agcagaagaa cgtcggaggc tgtttgatga
    12061 tataaggaaa aacagcccga aagcaggaag accaaccgtg aataaataga gtgttttatt
    12121 acacactatt aaaggggata aaaatatgct cataaagata attaaatctg tattcaattt
    12181 ttacatgctc tgtgtgcagc cttttattgg actggttctt gcgggttatg gtgcatggaa
    12241 attttcaggt gacagtatct cagcattact ggaaccagca tcgtactttg tcattggaac
    12301 tgttgttttg tttgtatggt atatagcatg gcaaaaagaa cgttctaaag aagaagagtt
    12361 taaatcaagt ataaaaccag aagattttgt gaagtgagga tacgtaataa taccagttta
    12421 taatcagaca ttagggcact caatctatgg aacactgcat ctttgattta ggcattataa
    12481 actatcatcc tgtcattaca tggacagtac cagttgcatt tttcttttta gtattgctgg
    12541 ctggtatagt attcaatatt ggcaggaaaa gtaatctaat cgttttcatc ctggcaatgt
    12601 tgctcccagt aacaacggtt ttcattttta tgttactggg cggtaagatc gatatgtgct
    12661 gaccaattaa aagaggatta aacaatgata aattcaatcg cgtttaatct tatagcgtta
    12721 tgtataatat atatatcatc actatttaaa aaaagtaact tcagaatatt ttatataact
    12781 gtatctacgt gctctttatt attatcatgt gtaccaaaca agtacggtat gattggtata
    12841 gcagcattgg tatttacaac tatgttagga ccattattaa ttattttaga ggataacaaa
    12901 caataaatta tgacaatgcg tttgttaagc ccgcaaatat gtgggcttat ttttaatttc
    12961 taatattttt actcttcatc atctcgcagg aactgacaaa agtcttcgct ccccatcata
    13021 tcgacagtat ttttaaattc gaaaaaagaa atttctgtca tagcacacac acgctggata
    13081 atcagttttt tcttttgctg tctgacggtt gcagtttcac caaactggat aacagcaagg
    13141 actgtttcat catatgattt caggacaaaa tcacaggtta tattctgcac ttcacggatt
    13201 aattctttta cagcttcctc gctaccatga ggacgaacaa attcaatgag tcgtattttg
    13261 ggaaaaacgg aataatcagg tataatatta cgtgaaagaa tgcctaaaaa ctctgattcc
    13321 ttatttgaga gtaagggtac tttagtaaaa caatcaacct ccccaatggc tgtaaaagca
    13381 ttggttgtca aagctggatt gttcttaata aaatcagaga atacattttc agttgatggc
    13441 aaaacaacag aagaattctg ttgttcatct cgttttttat tacggttaaa tatcatttca
    13501 tattcctttt aaaagagcct gcggcaggca caggaaaaaa catcgttttt ggacaatcat
    13561 ggataaaatg ttaacatttt gaccatgatt gtctatcctg cattgttctt tactgtctgt
    13621 aagatcagcg ctcattcttc cggcgttctc ccgataccaa aaagacggaa cgcaaaacgg
    13681 ctttcgatcc accattcaaa aatctgctct gcgcaaccac aaacagttaa ggcgatccat
    13741 gcagcaagaa caatgtaacc actgacatct gcacccatgt accaggcgat agttaacccc
    13801 atcactgcga taccgcctaa aaactgcaac aagaaacgaa atcccgcaag aatccccaat
    13861 ggaataacaa caaccagata aagggaagca gccagaaggt atctgacagg tgtcagcaga
    13921 taaaagaacc tggatgtttt ctttttgtca gaataaacgg catcatttgc aacatctgtt
    13981 gaatgagcgc ccaggtctct cctgatacgt tgaaaatcca cgatgttatc tttcatatca
    14041 tcctctcttt taagtgagtt ataaaaagag aaaaaacagg taacgtaaac agtagcattc
    14101 tttaatcact aaaccagaac gactcttcga aatcccatcc ggttatttca tgccataact
    14161 taaccttctg aagatctggc cttgataatt ttaacttatc atcatattcc cttaaagaga
    14221 taagataatt tttcataaca tcgatacatt tttttgccca ggctacctcc gcagagcttc
    14281 ctttaatgac ccttggtctt gatggcaatc gagggcgtaa cggtttagtt gctatttttt
    14341 ttccatcatg tgtttcattc tctacaagat atgtgaacac aacagactcg atctttctgc
    14401 cggacttaat accttcatag gtaacactca gattcgtatt tgcattgata atatcaacag
    14461 caggatcaag cacccgtttc ttaaaatcct tatatactgg atatttccct gtaagcccgg
    14521 ttcgctcctt catccattca atggttatag gatctgtcga gatcactcca ctatgtttct
    14581 tatttctgtt cagattctta tatttataca accatgaata aagtcgaaat gaaaatggcg
    14641 tatccagttt caccatatgt tcaagattca tttgtgtaaa ttcgcttttc agttcataaa
    14701 gatattgact aaccgaatct gaaaaacgca aagttatgtc actttcacta ttcccaacac
    14761 catatcttat tgaagaaaac cagaatcgtt tgactgcatc gatccttttt tttgcctcgt
    14821 tccattcata cgtaacaatt ggctttgagc ctaaagaact cgcagcagat tttaactgtt
    14881 cataacaatt tttcgaatct aaagaaaaag tgtccctgta ttccttcgca aacaatgtat
    14941 attcatttgc aggctgtggt ttacggctat caatcttagt caatgccaga tacagaagac
    15001 gcatttcaat tagcgttata tcgtatgcac cttccagcaa ttgatttccc tgtgccaaca
    15061 aactttgaac atcattacag tcgctatttt tattattctt taagaccata cagctcccct
    15121 tcctgtgagt taaaaatcaa aagaagtttc tcacacccaa attagggacg caattttttt
    15181 ttgtccctat atagctaata aaccataaat ctgtcccctg tttgaagggt caaacctggc
    15241 tgaacggcgc attttcaccc tcagtcagag gcagtcaata cagcaaacca ggagggaatg
    15301 catcatcaaa aacccatcga gccaaacatc ctaaatgtga tctaagtcac taatccaatt
    15361 cagattcata gagaatccat aacgaatccg agttgaatct aaaaaaagtt atccacaacc
    15421 tgtggataaa aaagttatcc acactaaatc tgtccctagt tgaccataaa tctgtcccct
    15481 tttaaccata aatctgtccc ctgataaaaa cgcaaataac cataaatctg tcccctttta
    15541 accataaatc tgtccctagt tagcattgca atcaattgaa aaacaaaaga aaaaacgacc
    15601 atgaaaaagg aaatattata tgtaacatag gagtgatcta tcttttagaa aaaagaaatt
    15661 agaaaaaaag aatagagcgc attgtgaatt ttttgagttg gaatcagcaa aatcacaaga
    15721 tgaggtcaga ccagagcgta cggattcata tgctgcatcg aagacattcc gcttcctcgc
    15781 tcactaactc gctccgctcg gtcgttcgac tgcggcgagc ggagtcattt ctcacatatc
    15841 gctggtaatt ctgttgttgt tccttcggtg atgagtcgct tgatagccta taaaacacgt
    15901 tcagaagcgt ctcaggcgca cgaaacgggt ttaaataccc cttagggcat gggaggcgcg
    15961 aaaaacgctt acagaggctt tctgttcatc agaatctgat cctgtgaaga ccgagaaagt
    16021 tctcatgttt agtcacaacc tgaatatttc attccgaggg cggtttaata taactagctg
    16081 attttattga aagagttctt ttaattatga tcctcatttt gctaaccgag gatcttctca
    16141 tgtttcaata aaataccttt aatatcaaca tgatatattc ttttgccaat tgatttatgt
    16201 gaccacttca tttcaacgat acataaatca acagatccag caatgcccct ccccaaagtg
    16261 tcacagagaa gccctgaatc gctctctgcc gcttcgttcg atacaaccat gaggaaaacc
    16321 atgcgaaatg aaaaaaatcg cttaaaacgc gatacagcgc gttttagggg gtattcacaa
    16381 aacacacgtt gccttgaaga aattttgatc aagatttaac tactatccgg atcatgacta
    16441 cagatcacag caacaaggct gctaaaaagc gttgagaggc gttaaacgct gttaagacta
    16501 gggctaagta caatgaaacg gaaaaaatgc tcagaatgcg ttacagaacc ttccagaaag
    16561 ctaggatttc tcactttaaa gagacatttt tcttgatctg ttgtcactta taagagacaa
    16621 tgtacacagg ttaagggaat gagggcggca agatgcctta cacggcgaaa cgatatcaga
    16681 cagaaaacgg tgaggttccg tacaccgact ggatgaaaaa attaagacgt aaagaccaga
    16741 ccgcagcgtt aaaggtggat tccagaattg cccgcgctat gggcggaaat tttggagatc
    16801 ataaattcga aagggacggt gtatgggaat tacgggttga ttacggtcct ggttacaggg
    16861 tttattattc aatcgaagat ggcgaaataa ttcttctgct cattggaggg aataaaaaaa
    16921 ctcagacagc cgatttagat aaagccgtta gttatctgca agattttaaa aagaggtcaa
    16981 aaaaatgaca gcaaccaaaa atgtgaagtc gcagaaaaat gattattcgg catccgttga
    17041 tcacaatgcc gccatgattg aagaattgcg cgcagatcct gattatgcaa acgcttatct
    17101 tgctaatgcc ctggaagaaa taaacgagcc tggtggttta ggtggttttc ttgttgcgct
    17161 acgtcaggta atcgaggcgc gaggggggat ttccgaagct gccaggaaat ctggccttgc
    17221 ccgtcagagt atttaccgcg cattatcccc caacggtaac ccgaccatca caacgcttgc
    17281 acaacttaca tcggtagccg gattacagtt cactctcagt aaatccagcc actaatctct
    17341 ccagttcccc ctaagcgggg gaatttccat gccatcaaaa ccgcagttat cccgcccgac
    17401 gttcaccggt atttaatcgg caaatcgtac aattgcgtac tggcaatagt ttaatggtgt
    17461 gtattaatac acatttaaag gcgatgtgga tgcgtgtgtt aatgctaatg tatgcataca
    17521 ttagcattaa catagagcag attctggcgc gttgcgcccg tagttcgctg atgctcacac
    17581 gcgcagtaca gcgccccgtc ctgttgcgac gcaccaggac ggcgtaaact cgcttgcgct
    17641 cgcgctaact gcggcattct gcggcgcaaa tcagcataat catggcctgc tggtcagtta
    17701 ggctttgcag ggtgaaggga tggccctgtg catcctggta cgttcgtcag cggctgcgcc
    17761 gcgcttcggg gcgatgtggc tcctgtgctg ccatggtatt ttcgttcgcc ccttccatcc
    17821 gcttacgcgg attaaaaaac gtgataacaa tcacttatcg agtaaaaaaa acgggagaat
    17881 acttgcaaat acgacttaaa ggtcgtatta ttatttcatc gaaaggggaa tggcccctct
    17941 cacaatagcc cagcagggca ggagatttaa aaaatgaata tccaggaagc attaaacgtt
    18001 tttggattat ccggcgaatt aactgaaaaa gatatcaaag cagcatacag aaaagccgcc
    18061 ttaaaatatc atccagatcg taacccgtta ggggctgaac tgatgaaagc ggtaaatgca
    18121 gcttttgatg tattgatggc aaatattgat aaaataaatc agttccagag tactgatgaa
    18181 catgctcgat ataattacgg tgatgacctg gaaaaagtat taaacgttct ttctggttta
    18241 tctggtctgg tatttgaagt gataggtaac tgggtctgga ttagtggaga aactattaca
    18301 cataaggaaa ctttaaaaga aatcgggtgt aaatgggcgg caaagaaaaa acaatggttt
    18361 tatcgtccag acgaacataa aagttactgg aatcgtgaag aacacacgat agaagaaatc
    18421 cgcgcaaaat acggtacaac cggacagcgc agggcgacag ggtggcaacg cgtggaaacc
    18481 agagtctaac cagaacgggg gcgagaagcc cccgatatta tagccagccc gtcttttggg
    18541 gcatcgaacc caaaaagacg ggaacaggag ccacgtagca aaaagggaaa cagatgaact
    18601 ctttttttga acaatatcac cctgtctttg aagttgtctg ccgtatcctg gggaacggct
    18661 ggcgcgtgaa caaacttgat gattgttcgt ctcgtataaa actgacgtca ccgcagttta
    18721 aaaattactc tgtgcatatt cggatggaaa aagaccggtt ttctgttgtg gggagtgtgg
    18781 atagtcgctc ctggcgtagt ccgcatcatg tttgcacgtt atccagaaaa cggaatcccg
    18841 ttgatattgc agccgatatc gagcgaaaaa ttctggtaaa tgcttcgcag gaggtgttac
    18901 aggcgattga gtatgagaaa caccaggtgg aaaaaaagga cgaaattatg atcctgaaag
    18961 gtatgttatc gcaacttgtc cagcttgaaa gctggtatgg ggcattgaca ggctttaaag
    19021 ctgaaaacgg attgaacggt aaagtcaccg aacagggcga cagttatgat ttacagattc
    19081 ggggcttgag tatagatcaa cttgttaaaa ttacagggta tttgaaacag ttatgagaaa
    19141 aaataaaggt gatgtgactt attttcttga aaaagaaggt gacaattaca ggcttacaaa
    19201 aaggataaaa gccagaacaa atgttaaaat cgggaacaaa actacgaaaa tcacattgta
    19261 tgatgccgta ctgaatgaga atgaattaca acatattgat tttacgtgtg ccggattaag
    19321 gaaagacgat gagacgccag ttaagaattt aattaaggag tttatgttaa atgaaacccg
    19381 ataatacacc tgaaaatgta aaaaaattac gtttaaaagc aggattaaca caaaaggaat
    19441 gcagtcatat ttatggtgtt gggctaagaa cctggcagaa aaaagaggaa gttaatactc
    19501 aaaacagtca aagtctgtca ctggttgagt ttgagtttct tttgttactt gcaggagaac
    19561 atcctgaata cgtgctctgc aaaagggagt caaaataaaa tgacctgtga tggttttata
    19621 ttagtacctg gagttgcgcc cgtagctcgc tgacgctcac acgcgcagta cagcgccccg
    19681 tccaggggaa ccctggacgg cgtaaactcg ctggcgcgag cgctaactgc ggcattctgc
    19741 ggcgcaaatc agcataatca tggcctgctg gtcagttggg ctttgcaggg tgaagggatg
    19801 gcctgtgctg ccctggtatt ttcgttcgcc ccttccatcc gcttacgcgg attaaaaacg
    19861 tgataacaat cacttatcga gtaaaaaaac gggagaacac ttgcaaatac gacttgaaag
    19921 tcgtattatt atttcatcga aaggggaatg gcccctctca caatagccca gcagggcagg
    19981 agatttaaaa tgaaatgctc atctgttttt acttcaacca ctaatcatgt tttcacattc
    20041 gaacgagtaa cgctttgcac tattatcctt atgcataagg atacgggaca acagtatgtt
    20101 gtcctattta ctgataacaa taaaattcgt gactataaaa ccggaattgt tcctcagttt
    20161 ggcgaactta agcagagtga tgttgattta gtccttttct acagggacga atatgaaaaa
    20221 tattttgatt cgttaaaaga tggcgatgaa tgcttgagtt ttaaagattt tattgagtgc
    20281 cttcgttaag cattataaat gcagggggga accctgcatt ttctggaaat ttcaatattg
    20341 attctgaaat tgtctattaa catcaatgca agggaaattc atgaaaacgt taaaacaagc
    20401 cgcaatgcag tttgcatctg atctgcgtaa taatcgctgt tttaaagctg cttataatga
    20461 tgctctgtta gagcttgatc gggaagattt aaatgccatt gtacaatgca catttctttt
    20521 tgagccaaaa cgaacattag ccgaacttga taaattaatt aaaaagatag aagtagaaga
    20581 agattatgag ttttgtgtat cccttgataa aggtaatgga ttacacgaag tcagaacatt
    20641 taaaagtgag cgtgaggcgt tggatgctta tcgcattttg accctttacg gatacacagt
    20701 aactatagaa aagaaggagg gtaatgactg gctattcaag gtgtgatcag gttgttccac
    20761 caacctgatc acgttatcga caatcaaaac tgaatgaggt ttttaaatgt caacgcggca
    20821 gatcgtacag cttgctgatt cccttgtcaa aggctgggaa accagaattc cggcaatgaa
    20881 atttagtgaa tgggatcaat tccggtggtg gttaaactac ctgcaagggt atgaaatgtt
    20941 ttaaataaaa aaaggggctt tctgcccctt tgtatttttt gacaaaaatg ctatgtgtag
    21001 atctgtattt acagtcttgt gtggaggatg gaaaggaacc tgataccccg tttaaaggcg
    21061 tgtttaacgt caggcttgat ccagaactgc atcgtcgggt agcagaaatg gcgatggaag
    21121 aagacttatc gttgaatgcc tttgttaata aggctctgga aaaagaagtc agcaatcatc
    21181 gcgcaggggc ttaattaccc ttgtttttta tgccctgtaa gggcatggga ggcgctttgc
    21241 gccggaagcc ccgcagcgca gcgaggactt aaaaagcgtt acggcttcag ccgtaacaat
    21301 tcccagccct gccaggcctg ttttttcttt cacagatcta tcagctatac gtttgccaga
    21361 tggtcgaaga cgaaagaacc tttcagcaac gaaatctggg catatgcagc gacgatttta
    21421 tagccaggca cagtgccaca tatggtacaa ccaatgcagg atagacaatc atggtcaaaa
    21481 tgttaacatt ttatccatga ttgtccaaaa acgatgtttt tgcctgtgcc tgccgcaggc
    21541 tctgttgggg tgagttatga agatgatagc gttcagactt agtgatgatg agttaaaact
    21601 tgcagagcat aacgctatat caagtgggtt taccagcatc aatacatttg ccaggcataa
    21661 tgtacttaat gttgatgttc aaccatcaaa tatacccgtc agcaatgaat catcaaaggc
    21721 tgttaaaacc tgtttatacc ctcatgaaat agaacttgtt aaacgtaatg cagcccttca
    21781 cggcatgagc atgagcagag aaattgctat tcgtgtgcgt cagtctttgt taaagaatga
    21841 agtctgtctt taccctgatg aagttaagga acttaaaaaa ttatcaactg ctgtagatcg
    21901 tgttggtcgc aacattcatt ttatcataaa aggtgaaaga ttttgcacgg ttaacgatcc
    21961 tgatttcaga aaagacgttg ttgaagtgat tgaactatgt aagcaaattg attcaaaact
    22021 tgaaacgtta accaagagtg ttgttaacag atttgggtga tttatgggtg tgtatgtaga
    22081 acaggaatac cgtattaaac gcgctaaagg gactgggcgt gatccgaaat ctcctaagtt
    22141 atcgggaaga catatacatg ccagtaaatc ggcttttaat cataaagtca gacatggcac
    22201 agacaagaaa gcatatacct ggacgccaac aaaagaagtc acttttaaaa tcacaggttc
    22261 agggaaaact gccgcaggta tcaaaaacgg tattgattac attacccgta atggtgaact
    22321 tgaggcttac tgttatgatg gaaaaggttc cgagcaaaca gggaaaggag aagactttaa
    22381 cagggagttt acttcaactt tatctaaagg aaatgattac tccagaacat atcgtggaga
    22441 aaacatcgat catgtgaaaa acatggtctt ttcaccacca ccagaagctg gagtaagcag
    22501 ggaagacgct ctgaaagcta cgatagaatt tcttaaagag acttatccaa accatgcttt
    22561 cgttgccgta taccatgatg ataaagaaga tcatcctcat gtacatgtta atattaaact
    22621 tcgtgatgaa gaaacaggaa ggagattaag acttactaag tctgaaacca ggaagttcag
    22681 aaacggtttt catagaaaac tgaaaggtat gggatatgat gttaccgcta catggaaaaa
    22741 agatcccgaa cgtaaacggg agattgagcg attacaggct gaaaatccga aaagactccg
    22801 gaatgtttac aaggttgtgg attttgggga gacttcatat cagaataagg caggggaaaa
    22861 acgaacacct ttcctcactt atgaaacttt aaaaggtgga aagcaggtta cgatttgggg
    22921 taaagacctg aaaaatcatt tcgagtctga aaagctccag ccaggaacgc ttatcaaagt
    22981 taaaaaactg gctcctacgc ttgtacgtag cccgatgttt aatgatgatg gaactgttgc
    23041 aggctacagg gaaacgcatc gcaataactg gcagattgaa aatattgccc ttgagcggaa
    23101 cagagaacgt caggttcatg agcgtgaaac caggcagccg gaagagagcg acgttaaaaa
    23161 gcagctatcc agaaaacatg agcaaggtca caatatcggg tttgctcttg aacacgggtt
    23221 tacaaaggat tcagaagaac ataaaaaact aagaatacag caagagagga actggaaagg
    23281 cctgggattt taatttgatt tcggcgcagg tgaacaaagc ggctactttg ctcacctgct
    23341 aatcacaaca acctacgagg gaggttatca tgactgagca tgatgctatc tgcatttctg
    23401 cacttcatca aatttttagt gatgaagaac atttgagtga gcaacaaaaa gacattattc
    23461 tgatgtacgc ttatggctat accctgaatg aaattgctga tttcaaagga ctaaagcctt
    23521 caactgtcag aaaatatctt gattctgtaa gagctgaact gggaggtgtc tcgttggcag
    23581 ggatcagaac actggtactc attcggacta atgcccttct cgtgtcaagt ctttccagga
    23641 tcagtgagag ggggaattta tgaaaaaata tctgcttttt gctttgccgt tcttcgttgt
    23701 tggttgtagt gaagaagtaa aaagtgtgga ttggtggggg cagcatctta cggaagctaa
    23761 acaaaagcag gcagagtgtg agaagtctgg ctctgattct cagaactgta agaatgttaa
    23821 acaagcattg tttattcagt ctcagaagga tgctccagtc cctacattcg attaactaat
    23881 gtttaaatca tactaaagcg cccatatggg cgcttttttt tgcatgatca cacgaatcat
    23941 aacatgacca ttttgtcaat ggtatttgat cgtattgttg agcattgtta ttttgcgaat
    24001 catgttcgca tctaaaacaa atccaaaaca cacttatagt ggattgatta aatgaaggag
    24061 aaaccagata agtcatcgga aaaaggggtt tatgtcacaa taaaactcga tccaaggttg
    24121 aatgcattta tcgaagagaa aacgaaaaca tctttgctta gtaagaggaa gcaaattatt
    24181 tacttattaa tgcagagtat gcgtattgat ggatatatgg agcgttagct atggcgtctt
    24241 tattcccagc attgttgctg tgtgcggcgt cagttcatcc ggatacgata aatgatattg
    24301 cacgggtcga gagtggcttc aatccttatg ctgtggctga aattattcct gaaagggaac
    24361 gcggtagcta tggcaaaagt gttatcagtc atatgcccaa aagtaaggag gaagctctta
    24421 cagttatcag agaaattgaa aacagaaaaa gacgttattc tgtcggattg atgcagatta
    24481 ccaacagtaa tttttctttt tattccacgt ccgcagaaaa actccttgat ccgtgtgaaa
    24541 acttgtctgt tttcgaaaag attatcgtgg attgttataa acgagggagg ggcctggaga
    24601 atgcgcttag ttgttactat acaggaaatt ttagtaacgg taagcgaaaa gaaaaagaat
    24661 ttaataatac aagttatgtt gagcgaattg gttatacagg gaacgaaaaa aaatatgttg
    24721 taccaggtac aagaagcaac gggggagaac agcgaaaaaa tcgttcacac aatgcgtcag
    24781 ttatctggcc cgaaaccatt ctgaaatctg cttttgttga taactcacat ccaacaaaag
    24841 ttattaatta acaggactta taaaatgtca tttaagaaat cagtatgtaa tcgtatcagt
    24901 tcatctgtca ctgctgtaat gcagcgtaaa aataaggtag ttatggcagt cgccggggca
    24961 acagttgcat caccggcctt tgcggatgga ttttcaaaag cggaaacgct gctggaaaag
    25021 gttaaaacag ggcttagtgg tctttcactg gtcacggtga ctattgcctg tctgtgggtc
    25081 ggctacaagg ttctgtttgg tggaagcacg attcgtgaat gctcacctat catcatcggg
    25141 gcaattgtta tcgccagtgc ggctgaagtt gcatcaatga tggttaacta ataaagcggg
    25201 gacgatagta tgtctacact ttataaagcg atgacacgcc ctgctatgta tgtgggtgtt
    25261 cctgtcgtcc ctcttactgt ggttgcaggg gcgttatttc tggcgggggt ttatatcagc
    25321 aagctgatct ggctggctat tcctgtcgcg gtttttgttc tcagaatgat aactaaacag
    25381 gacgaccaca tttttaacct ttactttctt aagctgaaaa tgctcggaaa ctcagtgtgt
    25441 aatcgttttt ttggcgcacg agcgttcctc tccggacaat atgaagctgt tgaaattgat
    25501 gagtttgtta atgccatgaa actgaatgag cgaatcacta ctggtaaata tatcccatat
    25561 tcaagccacg ttgataaaaa catcgtcaaa acaaaaaacg gtgattatgt agcgacatgg
    25621 caactgatgg ggattaactt tgagtcaatc tctgcggaga tgttagaaac tattgactca
    25681 caggttgcca ctcttgttcg ttcattttcc ggactgcccg tttcatttta taaccattca
    25741 tgcagggcga gtttttatga tgcctttacc acaaaatcag gtaataaata tgctgatata
    25801 atatcagatt gttattatgg ttcgatgaag aaaaataaat tcaaggggaa cactctttac
    25861 tttacgctga tctacagacc agacgggcgt gtagaaaaac tggaaaaacg caaaaaaagt
    25921 attaaagaaa agaaagatga tattaacatt catgtgaaga gaatgaatga aatgattaat
    25981 acattctctg gcgctcttga taaatttacc tgtaaacttc ttggtatgta tgaggagaac
    26041 ggaaaggtat tttcttctca actgtcattc tataattatc ttctgacagg gaagttgcaa
    26101 aaaatcagag taactgattc tccggtgtat aacgttcttg gtggagtgga tgtgtttttt
    26161 aaccatgata ccggacagat atgccgcatt gatggaaata aattctttcg ttctattgaa
    26221 attaaagatt tctgtagtga gactgcatcc ggtgtttttg atgtgctcca gtattctgat
    26281 gctgactata ttattacgca ttcatataca tccatgagca aatcagaagc attgagtacc
    26341 attaaacgtg cggaaaaaca gttaaagagt acagaagatg atgcggttac tcaattgcag
    26401 gaactggaaa aggcaaaaaa tgatattgtg tccggtgata tatcctttgg ttactaccat
    26461 ttcacgctaa tggtaatggc ggacagtatc agggagcttg acgaatctgt aagtaaaatt
    26521 acggcagact ttactgacct gggcattatt ccggcattgt caaccatgtc attgccagcg
    26581 gcatattttg cccagcttcc ggcggttttt catttaaggc cacgtttatc tccggtatcg
    26641 aatgtaaatt ttgtcgaact ggcatcattc cataatttct accaggggaa acgcgataaa
    26701 aactgctgga cagaagcggt tgctattctc aaaacaccaa gcaaacaggc gtattatctg
    26761 aatttacata actcagtact gtttaaagat gaaacaggtg aaaagaatct tgctaatact
    26821 aaagttatag gaacggcggg ttcaggtaag acaatgtttc tgtcatatct tgcctgttca
    26881 ttacagaaat acaataaccc cgaaactttt gctgattctg caaaaaataa gaagttaacg
    26941 tgtgtctttc ttgataagga cagaggggct gaattatgta tccgaatgct tggtggggaa
    27001 tattacaccg taaaaagcgg tgagccgaca ggatggaatc cttttgctct ggaggcaaca
    27061 aaacgtaacc gtatttttgt caagcaactg atggagattc tgtgtaccag aaatggtgaa
    27121 agattatcga caagagaaag attgcttatt agcgaaagtg ttgatgctgt gatggatttt
    27181 cctcctggcg aaatgcggga atatggcatt accagaatgc ttgagcatct tatgcagaga
    27241 gatgatcggg atgagcagga gaacgggatt atccttcggt tgtcccaatg ggctaatggt
    27301 caggctcatg gctgggtttt tgataatgct aaagacacat tcaatattca gcatgtcaat
    27361 aattttggca ttgatggcac cgagtttctt gatgatccga tggtatgtgc accaattact
    27421 ttctatctgc tgtatcgcat tacgcagctt cttgacggtc ggcgtcttgt tatcttcctg
    27481 gatgagttct ggaaatggct acaggatgaa gcattcagcg actttgtcta taacaagctg
    27541 aaaacaattc gtaagctgaa cgggctggtt attccggcaa ctcagtctcc ggatgaaata
    27601 ctgaagaata agatttcacg ggctgtggtt gaagtatgca gcaccagtat ttatctggct
    27661 aaccctgatg ccgattacaa tgattatgtg gaagggctta agctgacacc agaagaattt
    27721 aatattgtta aaaatcttga tccaatgtcg agacagttcc tgattaaaaa aagcagtctt
    27781 aaaaaggggg atggtaaatc attttcagca cttgcgacac ttgatttatc gggacttggt
    27841 ggatatctga aaatattgtc tgctagtgca gataatctgg aaatttttga aagtatttat
    27901 catgaaggaa tggagcctga tgactgggtt cctgaatatc tcgaacgggc aatctgacag
    27961 gtgaatttat gaagcgtgta aaaacattta tgctgatatc attattgacg gcttcatttt
    28021 atagtagcgc aggaattccg gttgctattg atgccagtcc ggaatgggct gttgaagccg
    28081 caagatggac agaacgactc aaacaatggt ccgaaactgc gcaacattat cagagtcaga
    28141 ttcaggcata taaagaccag ttagccacgg caacaggtat aaggaatatt gcggcattca
    28201 caaatgaact aagtaatcta caatcagaac tgacaaatat ttataagcag gggaacagtt
    28261 atatttctga ttttaccagt aatcccgaag gtgcattgag cagccaggct aaaaatctgt
    28321 tcagcaagta tggagccttc gatatgtgta atacgggcta tgaacgtaat gataatctct
    28381 gtaaagcacg gattgtgtca acggctgcca gtattgaaca gggaaatgag atcaataagc
    28441 agttatcaaa tgcaatgtct cagattcaga gtttaagtag ccgaattgag gcttcaaagg
    28501 atatcaaaga atcccaggat ttggctaacg cattacaggc gcagtcgtta aaaatgcagg
    28561 cgataaaaat gcagtatgat gtctggaata ataaaaataa agcagatcat gagatgttga
    28621 tcacacaaga acaagaggcc tttattaaac agcagaaaga agctgaacca ttaacttttg
    28681 attaaaaggt ggatatatgg ctcaggggtt tttcgttaaa tataattcta ccgttatgga
    28741 ttcggtagat aaaatcagct ccagttatca aacacaattt gctaatgata ttatgtcgtt
    28801 agcgacggta tcggttacgt tatatgtact atggaaagga tatcaaatac ttgccagtaa
    28861 aactcagacg cccttgcagg atttagtatg ggatctatca aaatttgcaa tcataatcat
    28921 gtttataact aatgcggatg ggtatttaac tgcggccact gatgcgttgc aaggcatgaa
    28981 agatggtttt tctggagggg tgagtgtctg gcaaacttta gataacttat ggaaaagtac
    29041 gcaaaatctt ggcgcggaaa tatactcttt agataaatca acatatgtta aagatcaagg
    29101 tgtagttgga cagtttttaa tatggactgg ctcgcttatt ttaatggctg ttagtgtggt
    29161 tgttttttta acagcagatg taacgatgaa actcctgatt attacagcac cgatatttat
    29221 cttttgtctt atgtttggtt ttattcggag catgtttaat aattggttac aatcgttatt
    29281 ctccagtatt ctgacagttc tatttgccag tttagtgatt cggatagcaa tggattttca
    29341 agggatgatc ctttcccatg ctattcgtgc tgcacaaaca ggaaatgtaa atcttgtatc
    29401 tacaggtgct atgggcttta tggctgggtt tttgggggct ttattggttc ttatagctaa
    29461 aggttttgct gtccagttag caggtgcagg tgttgaaggt gctgttcagg gcgcagccat
    29521 gatggggctg ggtgctgctg gtatggctac tggtaagtct ctgatgcttg gcggtcgtgc
    29581 tggtttaggt tttggcttag ggatggccgg aagaacgggc atgaattctt tatctgggaa
    29641 agcagggaat ctgatggggc gtggtgcgcg aacagccgct gaatgggcgg gtgaaaaggg
    29701 atatcaggcg ctggctccga caggtgcttt ggggatgaag gcgagaagac ttgcatccct
    29761 ggaaaaagca cgagcgagga atgccgcatg aatataatga aacgtttttt ttatgtgatg
    29821 tccctgaact ggatactgac gtttgttgat aaacatatca cctccggatg gagcaggaag
    29881 agaaagctaa taacccagct tattatttta atcacgggaa ttaccttatt taaggtctta
    29941 ggtggaatca gtcagagctg gttgtgacat gcttcattat tttgtcatga tactttattt
    30001 tgtcctaatc cttcttttag gagtgtttac ctgcttcgca ggaataagac ttggtttagg
    30061 gcttgcgggg aaatggagaa agggtatgga tcttcgcttt ttgcttctta ttggtgggat
    30121 tctttttctt catcttggcc tttatctctt aaaggtgttc gtgaacgctt aataaggtga
    30181 atttatgcga tgtgtgattc ttttgttttt cctgtttcag atttccggat gtaccacaag
    30241 gaataccctt ccttctgatg tttccggcga actggaaccc attaaccaca gccaggtaat
    30301 cagttatgag tgaaaaaatc gaaaagaaga ttgagacagc taaatccttc gaaagacaac
    30361 tctatgcaga aaatgaacgg tctaagaaaa atgcatggcg tgttgcagtg gcagcatcat
    30421 tactgtcctt atgtcttggg gctgcaattt gtgttcttgt gccattaaaa gaaaaagagc
    30481 ttgctattgt ggctgttggc gaaaaaacag gccgtacaga actgattact caggttaaac
    30541 aggaaaagat cctgcaatct gaagcgcttg ggcggtattt tgtaaacacg tatattactt
    30601 tacgtgaagg ttataattat ccgtctcttc agtatgatta tgagactgta cagctatata
    30661 gctcgaatac agtaaaggac gattatcttc gtctgtataa cagcgatatg gctcctgata
    30721 aaatttatca taataacggt tcttacgttg cggttgaggt catctccaat attatttctg
    30781 acgcaaccgc gccagataaa ctggcctctg tgcgttttaa aaaaacgacg agaaacttca
    30841 cgaccggaca ggtttcagtt tcatactgga cggctcgtgt gacatatcgt tttgaaccag
    30901 aaaagtcggt taaaagttcc agtcgtgagc ttaatcctct cggttttacg gtaaccagtt
    30961 accagacaga tcgggaagtc aggggggaat gatgaagaaa ttatttattg ctacatgttt
    31021 attgcttcct gggcttgtgt attcagcagc gactccgtta ccttctggat ttgatgcaag
    31081 gatgcagact gtgagttata acggtgcgaa tacgaccgtt atccggtcaa agacaggatt
    31141 tctcacatca gttgtttttg atgaaggtga ggctgttatc agtgcaaagg ctggttttcc
    31201 tgccggatgg gaaatcacaa ccgatgataa tgttgtttac atcaatccgc gtcccgttgt
    31261 tcaggaacag gaaggcgatg aaggcgaaaa actgaaaaag gttttccagc caacagaaaa
    31321 ggaatgggac acgaatcttt ttgtcagaac aacaaagcgg atttacagtc ttgatctaat
    31381 ccttctgtca gaagaaaaac aagcgcaacc tgcttatgtt gtacaattcc gctatccatc
    31441 agaaatagcg aaaaagaatg cagaagaagt aaggctggca aaagaaaaac aggaaaaact
    31501 cagacagaag aaactgattt ctgaaagttt tgaaaaagcc gatgcgccta aaaactggga
    31561 ttatttcatg cgagtcaatg aaaaatatga cagtcgtcgt atcgcccctg attttgctta
    31621 tgataatggc atatttacct ttttaggttt taactcaggg aaagtattcc cagctccatt
    31681 tgctgtaaga gatggtcagg aacagacact tgcttttaat gtggaaacaa aaggcaagta
    31741 taaaatcatg gttatccaca acgttaatga caaatttgtt ttacgctatg gaaacagcgt
    31801 tgttggtgtt gtgaataaat ctttcggaaa agtattaacc gaccagagga atacatcttc
    31861 tcctgcggta gaacgtgttg aggtgaataa tgactgatat gaaaaaaaca gatgatttag
    31921 ttgatgatgc gaatcagtca aagctggaaa gtaaacccgt tcatgatatc ggtgatatca
    31981 ggaacaaaaa taatcgtatg cgttctggct ttctgtttgg tctgatggct gtattagtta
    32041 ttggtatttt tgcgctgaaa acatataaaa attattttgc agatgaccag cagaaagcat
    32101 cagaatcaac aggcgatacc agcatttctc aggtaagtaa aatccgtact ggtcttggtc
    32161 agaattttga ccctgttgag aacaaagcaa ttatcaatcc aggcgctact ggttctggta
    32221 atactgtttc tgacggtcat aaagaagtgc cacaggaggg gttcaggaaa tatttgtcaa
    32281 tacctgttgc tggtcaggga gggagtcaga ctggcgcgag tggcagcagc aggacatcgc
    32341 agacatcaga gccacaggaa gaaaggaaag aatcaaaaga aaatgtgcct ggtaaatcag
    32401 gaatgaaagt gactgcgatt aatctcgatc ctgatctcta tattgaggaa aacaggctta
    32461 taccgtgtgc tttaaccaca cgctttgttt ctgatgttgc aggtcgtatc agttgtgttt
    32521 ttacagaaga tgtatggagt gctaatcacc acacaaaatt actggaacag ggaactaagg
    32581 cttttggtcg ttaccagacc ggaacgctga atcatggaca gggcagaatg ttcgttatgt
    32641 gggagcagtt gcggacgcct gataataaac gaatcgatat ggtaaataca gcagcggctg
    32701 gtcccctggg ggaagcaggc attgatggat ggatcgattc tcacttctgg gagcgttttg
    32761 gtggttctct tatgctcagt atggttcagg atgtagcggc ggcggcggcg gataatgcac
    32821 ctggtaaaga tcgtaatgtg gattataccg aaaactcacg acaggcaatg gctgaaatgg
    32881 ctaaagttgc acttgagaat tcgataaata ttcctccaac aatgtataaa aaccaaggtg
    32941 acataatcac tattatggtc ggggaagaca ttgatttttc tgatatctat gagttaaagg
    33001 taaaatagta tgagtggcgt tattcctgtc agcattagca ataaatcgct cgatttttat
    33061 aaaaatcaag tattccagtc ttttcttgat attgaagggc taacagaaat tgctgtcaac
    33121 cgtcctggtg aaatctggac ggaaattaat ggtgactgga cattccataa taatgacggt
    33181 gtgacctttg atttttgtaa acgtttttct cagacgctgg catcatttcg gggagatgaa
    33241 atcggcgata ccaagccatt actttcagca acactggaat caggagaacg tgtacaggtc
    33301 gtttttcctc ctgcatgtga gagaaatact atttcaatca ctatacgtaa accatcgaca
    33361 cggcagataa cgcataaaga atatgtggcg aacggttttt atgattatgt ccagtcagga
    33421 aaaaaacaca ggacatacga tgatgagctt cttgatttat tcagagcgag aaatatcgct
    33481 gcttttatgg agcttgccgt agcagcaggg aaaaccattg tatttgccgg agcaacgggt
    33541 tccggtaaaa caacctatat gaagagtctc atcgatttca taccattgaa tacgcggctg
    33601 attacgattg aagatgcgga ggaaatcaaa ttttttattc ataaaaatta tgtgcatctt
    33661 ttttaccctt cggaatccgg cagtgattcc ggctctatca taacagcagc gaaattaatc
    33721 aaatcctgtt tgagaatgaa acctgacaga attttactgg cggaaattaa aggtggcgat
    33781 gcctgggatt ttgtgaaagt tgctggttct ggtcacagtg gaagca
//
