LOCUS       NZ_CP085893            23957 bp    DNA     circular CON 23-DEC-2023
DEFINITION  Klebsiella pneumoniae strain 8695 plasmid p4, complete sequence.
ACCESSION   NZ_CP085893
VERSION     NZ_CP085893.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN22599454
            Assembly: GCF_020736285.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 23957)
  AUTHORS   Xu,M.
  TITLE     In vivo emergence of ceftazidime-avibactam resistance and loss of
            hypermucoviscosity in carbapenem-resistant Klebsiella pneumoniae
            during antibiotics treatment
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 23957)
  AUTHORS   Xu,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) Laboratory Medicine, College of Life
            Sciences, Wenzhou Medical University, Wenzhou Medical University,
            Wenzhou, Zhejiang 325000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: unicycler v. v0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/23/2023 20:23:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,916
            CDSs (total)                      :: 5,794
            Genes (coding)                    :: 5,614
            CDSs (with protein)               :: 5,614
            Genes (RNA)                       :: 122
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 180
            CDSs (without protein)            :: 180
            Pseudo Genes (ambiguous residues) :: 0 of 180
            Pseudo Genes (frameshifted)       :: 73 of 180
            Pseudo Genes (incomplete)         :: 112 of 180
            Pseudo Genes (internal stop)      :: 22 of 180
            Pseudo Genes (multiple problems)  :: 26 of 180
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP085893.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..23957
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="8695"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="p4"
                     /geo_loc_name="China:wenzhou"
                     /collection_date="2020"
     gene            1..1257
                     /locus_tag="LKW25_RS29355"
                     /old_locus_tag="LKW25_29355"
     CDS             1..1257
                     /locus_tag="LKW25_RS29355"
                     /old_locus_tag="LKW25_29355"
                     /inference="COORDINATES: protein motif:HMM:NF024108.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_228015059.1"
                     /translation="MFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSAMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLV
                     AGFNLSETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     KLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFRRWPHASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPADFV
                     KTTVLDNTPIRWFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARLAFSSPLRVERREISLKTFPVLAKTDPLAEY
                     LPPADGGGPKADDDFAGLY"
                     /name="TraM recognition domain-containing protein"
     gene            1257..1992
                     /gene="mobC"
                     /locus_tag="LKW25_RS29705"
                     /pseudo=""
     CDS             1257..1992
                     /gene="mobC"
                     /locus_tag="LKW25_RS29705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /name="mobC"
     gene            1999..2229
                     /locus_tag="LKW25_RS29370"
                     /old_locus_tag="LKW25_29370"
     CDS             1999..2229
                     /locus_tag="LKW25_RS29370"
                     /old_locus_tag="LKW25_29370"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_228015065.1"
                     /translation="MALYMVFIEDVEDKDGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKSHVLFHR"
                     /name="hypothetical protein"
     gene            complement(2558..2737)
                     /locus_tag="LKW25_RS29375"
                     /old_locus_tag="LKW25_29375"
     CDS             complement(2558..2737)
                     /locus_tag="LKW25_RS29375"
                     /old_locus_tag="LKW25_29375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165970.1"
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(2763..3191)
                     /locus_tag="LKW25_RS29380"
                     /old_locus_tag="LKW25_29380"
     CDS             complement(2763..3191)
                     /locus_tag="LKW25_RS29380"
                     /old_locus_tag="LKW25_29380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001140599.1"
                     /translation="MAKTLLNLSQAAQAAGITRRTLYNHVKQGKVTVSRDGKNNPVVDV
                     SELIRVYGNVNIPEKQIPGISHRENTQKNFPQEQLLAMQKELADLRQAVTLMLEDKTSR
                     EEERRQHDDERRKLQAEVDRLTTELTQKKKRFWSGWFS"
                     /name="hypothetical protein"
     gene            complement(3355..3669)
                     /locus_tag="LKW25_RS29385"
                     /old_locus_tag="LKW25_29385"
     CDS             complement(3355..3669)
                     /locus_tag="LKW25_RS29385"
                     /old_locus_tag="LKW25_29385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136729.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]; GO:0009432 - SOS response [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_071177730.1"
                     /translation="MPQVTISALAQRDLQRLQDFLKTKNRLAARKGGEVIVRAIQQLKT
                     LPDIGRPVPFLPLEYKELVIGFGDSGYVMLYRHDREMDQIVIVTVRHQKESGYPGADSL
                     "
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(3657..3935)
                     /locus_tag="LKW25_RS29390"
                     /old_locus_tag="LKW25_29390"
     CDS             complement(3657..3935)
                     /locus_tag="LKW25_RS29390"
                     /old_locus_tag="LKW25_29390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014542884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family ribbon-helix-helix protein"
                     /protein_id="WP_000093040.1"
                     /translation="MSSATSIRLDEELKDRLKTLADDRHRSAHALMLEAITEYIDREEK
                     RSQYLRDGQAAWQHYQETGLHLTAEEAEAWISTWGTENEQDAPPCHR"
                     /name="CopG family ribbon-helix-helix protein"
     gene            complement(4110..4475)
                     /locus_tag="LKW25_RS29395"
                     /old_locus_tag="LKW25_29395"
     CDS             complement(4110..4475)
                     /locus_tag="LKW25_RS29395"
                     /old_locus_tag="LKW25_29395"
                     /inference="COORDINATES: protein motif:HMM:TIGR01352.1"
                     /GO_function="GO:0015291 - secondary active transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="WP_072354022.1"
                     /translation="MKAFTLTVLAAMFLTPVHAIPLKPVTTLQPTYPVQAAAKRIEGQV
                     TATFDILDDGRVDNVSLTGCHLFFRETLTAMRHWLYPAGHPAMRQVINFEFSLKNDGLQ
                     DPRPVTTQKLNDDGCRQ"
                     /name="TonB family protein"
     gene            complement(4472..4843)
                     /gene="tolA"
                     /locus_tag="LKW25_RS29400"
                     /old_locus_tag="LKW25_29400"
     CDS             complement(4472..4843)
                     /gene="tolA"
                     /locus_tag="LKW25_RS29400"
                     /old_locus_tag="LKW25_29400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237044.1"
                     /GO_component="GO:0098567 - periplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="WP_001237044.1"
                     /translation="MRLIPFILLALCSPLLLTACKHSTTQPPKIYTLDKSSKISSYAAA
                     IKTAVEMQMFEPEAYAGKMCTVRISIQRDGTLNSAIAEGGDPKLCKAAISAVTHAKIPP
                     APDENTWQIFKNAPLDFRP"
                     /name="tolA"
     gene            complement(5117..5362)
                     /locus_tag="LKW25_RS29405"
                     /old_locus_tag="LKW25_29405"
     CDS             complement(5117..5362)
                     /locus_tag="LKW25_RS29405"
                     /old_locus_tag="LKW25_29405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032440458.1"
                     /translation="MTHLKLTPAEEKRLADAFVAQALAMGLKGNKTLPKAVKQQVRERV
                     LRAIQDEREARRAQEMRREKYEATETTFTWQPQRRR"
                     /name="hypothetical protein"
     gene            6007..7496
                     /gene="ltrA"
                     /locus_tag="LKW25_RS29410"
                     /old_locus_tag="LKW25_29410"
                     /pseudo=""
     CDS             6007..7496
                     /gene="ltrA"
                     /locus_tag="LKW25_RS29410"
                     /old_locus_tag="LKW25_29410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226014.1"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /name="ltrA"
     gene            7601..9297
                     /locus_tag="LKW25_RS29415"
                     /old_locus_tag="LKW25_29415"
                     /pseudo=""
     CDS             7601..9297
                     /locus_tag="LKW25_RS29415"
                     /old_locus_tag="LKW25_29415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            9300..9557
                     /locus_tag="LKW25_RS29420"
                     /old_locus_tag="LKW25_29420"
     CDS             9300..9557
                     /locus_tag="LKW25_RS29420"
                     /old_locus_tag="LKW25_29420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /GO_function="GO:0015643 - toxic substance binding
                     [Evidence IEA]"
                     /GO_process="GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3-like toxin immunity protein"
                     /protein_id="WP_032440455.1"
                     /translation="MGLKLRLTWFDKKTEEFKGEEYSKDFGDDGSVIESLGMPLKDNIN
                     NGEFDLKKEWVPLLQPFFKNQIKPDVDNCYIAFDYRDGNW"
                     /name="colicin E3-like toxin immunity protein"
     gene            9642..9791
                     /locus_tag="LKW25_RS29425"
                     /old_locus_tag="LKW25_29425"
     CDS             9642..9791
                     /locus_tag="LKW25_RS29425"
                     /old_locus_tag="LKW25_29425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_032440454.1"
                     /translation="MKKVKTIFLFILIVAGFLLAACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            11275..13239
                     /locus_tag="LKW25_RS29430"
                     /old_locus_tag="LKW25_29430"
     CDS             11275..13239
                     /locus_tag="LKW25_RS29430"
                     /old_locus_tag="LKW25_29430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_071177727.1"
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYSLAGFFLVIGLFF
                     GLAELWAGRMRFVGLSHKARREYADRYKRDNNRTVPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLV
                     AGVLLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSTEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSAMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLV
                     AGFNLSETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     KLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFRRWPHASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPADFV
                     KTTVLDNTPIRWFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARLAFSSPLRVERREISLKTFPVLAKTDPLAEY
                     LPPADGGGPKADDDFAGLY"
                     /name="TraM recognition domain-containing protein"
     gene            13239..13970
                     /gene="mobC"
                     /locus_tag="LKW25_RS29435"
                     /old_locus_tag="LKW25_29435"
     CDS             13239..13970
                     /gene="mobC"
                     /locus_tag="LKW25_RS29435"
                     /old_locus_tag="LKW25_29435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_071177728.1"
                     /translation="MTLEQYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQVSVWGLTPHGVAFSFDEDEPLTDVIPFQP
                     SRVSAAQLPHRLAVQSLRLSMEGRGATGWRYLHRMALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRRANGIDEIWYICPDRPTLVRVQRAILAVDEIVNPQTGEA
                     RKTVELDRERLFACFKFMTTE"
                     /name="mobC"
     gene            13977..14507
                     /locus_tag="LKW25_RS29440"
                     /old_locus_tag="LKW25_29440"
     CDS             13977..14507
                     /locus_tag="LKW25_RS29440"
                     /old_locus_tag="LKW25_29440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_071177729.1"
                     /translation="MALYMVFIEDVEDKDGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGENPQWERDKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIEVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(14534..14713)
                     /locus_tag="LKW25_RS29445"
                     /old_locus_tag="LKW25_29445"
     CDS             complement(14534..14713)
                     /locus_tag="LKW25_RS29445"
                     /old_locus_tag="LKW25_29445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165970.1"
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(14739..15167)
                     /locus_tag="LKW25_RS29450"
                     /old_locus_tag="LKW25_29450"
     CDS             complement(14739..15167)
                     /locus_tag="LKW25_RS29450"
                     /old_locus_tag="LKW25_29450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001140599.1"
                     /translation="MAKTLLNLSQAAQAAGITRRTLYNHVKQGKVTVSRDGKNNPVVDV
                     SELIRVYGNVNIPEKQIPGISHRENTQKNFPQEQLLAMQKELADLRQAVTLMLEDKTSR
                     EEERRQHDDERRKLQAEVDRLTTELTQKKKRFWSGWFS"
                     /name="hypothetical protein"
     gene            complement(15331..15645)
                     /locus_tag="LKW25_RS29455"
                     /old_locus_tag="LKW25_29455"
     CDS             complement(15331..15645)
                     /locus_tag="LKW25_RS29455"
                     /old_locus_tag="LKW25_29455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136729.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]; GO:0009432 - SOS response [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_071177730.1"
                     /translation="MPQVTISALAQRDLQRLQDFLKTKNRLAARKGGEVIVRAIQQLKT
                     LPDIGRPVPFLPLEYKELVIGFGDSGYVMLYRHDREMDQIVIVTVRHQKESGYPGADSL
                     "
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(15633..15911)
                     /locus_tag="LKW25_RS29460"
                     /old_locus_tag="LKW25_29460"
     CDS             complement(15633..15911)
                     /locus_tag="LKW25_RS29460"
                     /old_locus_tag="LKW25_29460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014542884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family ribbon-helix-helix protein"
                     /protein_id="WP_000093040.1"
                     /translation="MSSATSIRLDEELKDRLKTLADDRHRSAHALMLEAITEYIDREEK
                     RSQYLRDGQAAWQHYQETGLHLTAEEAEAWISTWGTENEQDAPPCHR"
                     /name="CopG family ribbon-helix-helix protein"
     gene            complement(16086..16451)
                     /locus_tag="LKW25_RS29465"
                     /old_locus_tag="LKW25_29465"
     CDS             complement(16086..16451)
                     /locus_tag="LKW25_RS29465"
                     /old_locus_tag="LKW25_29465"
                     /inference="COORDINATES: protein motif:HMM:TIGR01352.1"
                     /GO_function="GO:0015291 - secondary active transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="WP_072354022.1"
                     /translation="MKAFTLTVLAAMFLTPVHAIPLKPVTTLQPTYPVQAAAKRIEGQV
                     TATFDILDDGRVDNVSLTGCHLFFRETLTAMRHWLYPAGHPAMRQVINFEFSLKNDGLQ
                     DPRPVTTQKLNDDGCRQ"
                     /name="TonB family protein"
     gene            complement(16448..16819)
                     /gene="tolA"
                     /locus_tag="LKW25_RS29470"
                     /old_locus_tag="LKW25_29470"
     CDS             complement(16448..16819)
                     /gene="tolA"
                     /locus_tag="LKW25_RS29470"
                     /old_locus_tag="LKW25_29470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237044.1"
                     /GO_component="GO:0098567 - periplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="WP_001237044.1"
                     /translation="MRLIPFILLALCSPLLLTACKHSTTQPPKIYTLDKSSKISSYAAA
                     IKTAVEMQMFEPEAYAGKMCTVRISIQRDGTLNSAIAEGGDPKLCKAAISAVTHAKIPP
                     APDENTWQIFKNAPLDFRP"
                     /name="tolA"
     gene            complement(17093..17338)
                     /locus_tag="LKW25_RS29475"
                     /old_locus_tag="LKW25_29475"
     CDS             complement(17093..17338)
                     /locus_tag="LKW25_RS29475"
                     /old_locus_tag="LKW25_29475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032440458.1"
                     /translation="MTHLKLTPAEEKRLADAFVAQALAMGLKGNKTLPKAVKQQVRERV
                     LRAIQDEREARRAQEMRREKYEATETTFTWQPQRRR"
                     /name="hypothetical protein"
     gene            17984..19473
                     /gene="ltrA"
                     /locus_tag="LKW25_RS29480"
                     /old_locus_tag="LKW25_29480"
                     /pseudo=""
     CDS             17984..19473
                     /gene="ltrA"
                     /locus_tag="LKW25_RS29480"
                     /old_locus_tag="LKW25_29480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226014.1"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /name="ltrA"
     gene            19578..21263
                     /locus_tag="LKW25_RS29485"
                     /old_locus_tag="LKW25_29485"
     CDS             19578..21263
                     /locus_tag="LKW25_RS29485"
                     /old_locus_tag="LKW25_29485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_032440457.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IMTSLPADAVTETPASTLPLDQATVRVRQRVVDVVKDERQHIAVVAGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPTAKAPPKGIVAEKGDSRPAGFTAGGNSREAVIR
                     FPKETGQKPVYVSVTDVLTPAQVKQRQEEEKRRQQAWDAAHPEEGLKRDYDKAKAELDA
                     EDKNIATLNSRIASTEKALPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQASLNAMNESLSRDKAALTGAMESRKQKEKKAKDAENKLNE
                     EKNKPRKGTKDYGHDYHPVPKTEDIKGLGELKRGDPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            21273..21530
                     /locus_tag="LKW25_RS29490"
                     /old_locus_tag="LKW25_29490"
     CDS             21273..21530
                     /locus_tag="LKW25_RS29490"
                     /old_locus_tag="LKW25_29490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /GO_function="GO:0015643 - toxic substance binding
                     [Evidence IEA]"
                     /GO_process="GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3-like toxin immunity protein"
                     /protein_id="WP_032440455.1"
                     /translation="MGLKLRLTWFDKKTEEFKGEEYSKDFGDDGSVIESLGMPLKDNIN
                     NGEFDLKKEWVPLLQPFFKNQIKPDVDNCYIAFDYRDGNW"
                     /name="colicin E3-like toxin immunity protein"
     gene            21615..21764
                     /locus_tag="LKW25_RS29495"
                     /old_locus_tag="LKW25_29495"
     CDS             21615..21764
                     /locus_tag="LKW25_RS29495"
                     /old_locus_tag="LKW25_29495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_032440454.1"
                     /translation="MKKVKTIFLFILIVAGFLLAACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            23248..23700
                     /locus_tag="LKW25_RS29500"
                     /old_locus_tag="LKW25_29500"
     CDS             23248..23700
                     /locus_tag="LKW25_RS29500"
                     /old_locus_tag="LKW25_29500"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_228015057.1"
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYSLAGFFLVIGLFF
                     GLAELWAGRMRFVGLSHKARREYADRYKRDNNRTVPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGRNRPAPGPLCERRLLPAAAG"
                     /name="hypothetical protein"
     BGC             2891..23957
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(9895..10473)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.282"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(21868..22446)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.282"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          1258..1496
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="96.25"
                     /coverage="100.0"
                     /evalue="4.86e-108"
     Typing          1646..1989
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="92.174"
                     /coverage="100.0"
                     /evalue="4.86e-108"
     Typing          13240..13967
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="93.416"
                     /coverage="100.0"
                     /evalue="1.37e-140"
ORIGIN
        1 gtgtttctgg gtaaggatga gcagggccag ccggtgctgg tccctcgtga tacctggcgc
       61 aagaccaata ttcagatcct cggcctgccc gggagcggca agagcgcgat ggccaccaac
      121 gcgctcattc gctgcgtacg cgatttcggg gacgctgtgg tgtacttcga ccccaaaggg
      181 gacgcgtggg cgccgcacgt cttccgggcg cactgcccgg acttcaccct gctggatctg
      241 cggccgggga aaccggcgca gctgaatctg ttccgcgatc tcgaccagta cgccctgaag
      301 aatctgctgg ttgccgggtt taacctgagt gagaccggcg acgtggcgga ccactaccgc
      361 atcagcgagc agaaagcggc gaagctgatt gcggagcagt tcccgcaggg ggcaaacatt
      421 cagcaggtgc tggcggcggc gtacgcgttg ccggaggccc tgaaaaagga cgtgaagggg
      481 ctgatcacca agctggagaa cgtggccgac ctgagcgtcc tgcagacgga cagcggtatc
      541 gatgtggcgg ggataatcaa cggcggcggc tgcctgtacg tcatcggctc gatggacgat
      601 gaggcggtga tccgggtgca gaagatgctg tttgcccgct gcgcgcaaat catcattgcg
      661 cgggatgagt tccggaggtg gccgcacgcg agcatcatgc tcgatgagat taaatatctg
      721 ctgtcgaagt acgtgctgaa cgcgctgggg acgctgcgca gccgggactg caacctgctg
      781 ctcgcgcacc agtcgctggg cgacttcggt cagtgcgggc aggatctgcc cgctgatttt
      841 gtgaaaacca cggtactgga taacacgccg atccgctggt tctatcgcgc ggccagccag
      901 gagtccgcgc agtgggcggc gggccagacc ggggagatcc gggtggacgt ggagcgccgc
      961 cgggccagcc gggaggcggg gaacgtggag cacatcagcg gcgacagctt catccagaag
     1021 gaggcgcggc cgctgtttga cgtgaacacc ctgcaacacc tgcctgacgg gttcgcggtg
     1081 atgaccgggc tgggcgtggc gcggctggcg ttcagcagcc cgctgcgggt tgagcgccgg
     1141 gaaatttcgc tgaaaacctt cccggtgctg gcgaaaacgg acccgctggc ggagtacctg
     1201 cctccggccg acggcggcgg accaaaagcg gatgatgatt ttgcggggct ttactgatga
     1261 cactggagca gtacaacgtc agccacgcga agcggcaggc gcggaacgcg gagaaaacac
     1321 ggctgaccct gcgctggctg cgggaagagc tgtgttccac ggcggagctg gttgcgcgac
     1381 ggctggggat tgcggcggta cagccggttt accgcttcct ggacagtctg gtggcgaaag
     1441 ggctgctggt ccgggcgaaa tacccggttg acggccgtca ggtcagcgtg tggggggctg
     1501 acgccgcacg ggggtggcgt tctcgttcga cgaggacgag ccgctgacgg acgttattcc
     1561 gtttcagccg tcaagggtgt cggcggcgca gctgccgcac cggctggccg tgcagtccct
     1621 gcgcctctcc atggagggcc ggggggggcc accggctggc ggtacctgca ccgtatggcc
     1681 ctgaaaggga tgaaagtgcc ggacgcgctg gcggagctgg acggcagaac ggtggcattt
     1741 gaggtagagc gcaccgtcaa gagccgcagg cggtatcagg aagtggtgtc cgggtatctg
     1801 ttcaaccgcc gggcgaacgg catcgatgaa atctggtaca tctgccctga ccggccgacg
     1861 cttgtccggg tacagcgggc gattctggcg gtggatgaaa tcgtgaatcc acagaccggc
     1921 gaggcccgca aaacggtgga gctggaccgg gagaggctgt tcgcgtgctt taaatttatg
     1981 acaacggagt gagggattat ggcgctgtac atggtattta ttgaggacgt ggaagacaaa
     2041 gacggcgagc gctgcattat gccaaccagc gagcatctgg aagacatggt ggtgctcgcc
     2101 tggcagaccg gggcgtatgt tttctgtttt gtcgaccggg cccagcatct ggcgatgatg
     2161 aaatccatcg ggatgtatga cgagcggctc aacagcgacg aaaaaagcca cgtacttttt
     2221 caccggtgaa aatccgcaat gggaacggga caaacccaca ggaatgaagc tgtgtgatta
     2281 cctctatcga aaggtggagc ggttcgccat cgagaacggt gtgcaggtgg ttgatgccgg
     2341 gaagtgctca ccggagcaga ttaacgcgat gattgaggtg gtcagcgagc ggcacgggga
     2401 aagcgcggtg aacgagaagc tgaaagcgga gctgatgcgg gaatataaca gccgctattt
     2461 taacgtgccg gtgcctgaac tgccggagga caaacccgcc cgccggtggt ggccgttcgg
     2521 caaaaaaata acgccagcac cggcatggcc ggtgctgtta ttcttccccg agcttatccc
     2581 gcatcacctg ccagagtgtt tccgcatcct cgtgaagccg ttcgcacatg tcggccgggg
     2641 tatccatgtc cagctcgttc agcttttcca gcaacagcag cgactgatcc ttaatgaatt
     2701 tagccatatt gagggcagtt ttttcctgct tcgtcatgtt ctccattccc ttcggtaagt
     2761 tctcagctaa accagccgga ccagaagcgt tttttcttct gtgtcagttc tgttgtcaat
     2821 ctgtccactt cggcctggag tttccggcgc tcatcatcgt gctggcggcg ttcttcttcc
     2881 cgggatgttt tatcttccag catcagggtg acagcctgcc ggagatcggc cagttccttt
     2941 tgcattgcca gaagctgttc ctgtgggaaa tttttttgtg tattttcacg gtgtgaaatg
     3001 ccgggaattt gtttctcagg gatattcaca tttccgtata cacggatcag ttctgacaca
     3061 tccacgacag ggttgttttt cccgtcacgt gacacggtaa cctttccctg ttttacatga
     3121 ttgtatagcg ttcttctggt aatgcccgcg gcttgtgctg cctgtgaaag gttgagcaat
     3181 gttttcgcca ctgtataccc ctgattttat cgggtgtgaa aggtgtgtaa tttctcacgg
     3241 taaatgtatc gctgaatttt acccgttttt ccgttcagga tgtggttttc tgacgcgctg
     3301 cgcttgtcaa accggcgacg gccacgcaat gaattgcgcc cccgtcatcg gttattagag
     3361 gctgtctgcc cccggatacc cggattcttt ctgatgcctg acggtgacga tcacaatctg
     3421 gtccatttcc cggtcgtggc ggtagagcat cacatagcca ctgtcgccaa acccgatcac
     3481 cagttcctta tattccagcg gcagaaacgg caccgggcgg ccaatgtctg gcaatgtttt
     3541 cagttgctgg atagcccgga cgatcacctc acctcctttt ctggctgcca gccgattttt
     3601 ggttttgaga aagtcctgaa ggcgttgtaa atcgcgctgt gccagcgcgg aaatcgttac
     3661 ctgtggcatg gcggagcatc ctgctcgttc tcagttcccc aggtacttat ccaggcttcc
     3721 gcttcttccg cagtaaggtg cagacccgtt tcctgatagt gctgccatgc ggcctgtccg
     3781 tcccgcaggt actggctgcg cttctcttcc cggtcgatgt attcggtgat tgcctccagc
     3841 attagcgcgt gcgctgagcg gtgccggtca tcggccagcg ttttcagccg gtccttaagt
     3901 tcttcatcga gcctgatgga tgttgctgat gacataaaag cccctttgta gtcatatgta
     3961 ttacacatga ctactttaat ccgtggcggc gctatttgcc agaaatacgg cttttgctgc
     4021 ccatttttca gcttcgcttc cactaatcag ggctgctaca ggctcactca tcatccagga
     4081 ctattgcagc ctgcgggtta aaggacctgt tactggcggc aaccatcatc attgagcttt
     4141 tgggtggtga ctggtcgcgg atcctgtaag ccgtcatttt tcagactgaa ttcaaaattt
     4201 ataacctgtc gcattgccgg gtgccctgcg ggatatagcc agtgcctcat tgccgtcagc
     4261 gtttcccgaa aaaaaaggtg acagccggta agcgacacgt tgtccactcg tccatcgtcc
     4321 agaatatcaa acgtggcggt cacctgacct tcgatgcgtt ttgctgcggc ctgtaccggg
     4381 taggttggct gcagtgtggt tacgggtttt agtggtatcg catgtaccgg agtgaggaac
     4441 atggccgcca gcactgtcag agtaaaagct ttcatggtct gaaatccaga ggggcgtttt
     4501 tgaatatttg ccaggtattt tcatccggtg ccggcggaat tttggcgtgg gtaacggctg
     4561 atattgctgc tttacagagt ttcggatctc ctccttcagc aatggcgctg ttcagagtgc
     4621 catcacgttg tatggatatc cgcacggtgc acatttttcc cgcataggcc tctggttcaa
     4681 acatctgcat ttcaacagcg gtcttgatgg ccgcagcgta gctactgatt ttagatgact
     4741 tatccagagt ataaattttc ggcggctggg tggtggaatg cttacaggcc gtcaggagta
     4801 aggggctgca caatgccagc aggataaagg gtattaaacg catcgggttg atgacctgtc
     4861 agtaaaaaat gttacatgta tatttgtcac tctttacggc cacgttcatt tacataaaca
     4921 cggcttatcg tatcgttttt acaccaaacg gcccgccatg cagttgcgtg cataggcatg
     4981 cagcgggtta caatttaccg ggcgcgtttc cggcggtttt ccgggtggtt tgttgcctgt
     5041 tttatcccgt agccgccgga aacgccctca gaccgtctga gcggtgcggg caatgcgacg
     5101 ttatggtaaa taccccttac cggcggcgct gtggctgcca ggtgaaggtg gtttccgtag
     5161 cctcgtattt ctcccgacgc atttcctgcg cccgcctggc ttcacgttcg tcctgaatgg
     5221 cacgaagcac cctttcccgc acctgttgtt ttaccgcctt tggcagcgtt ttgttccctt
     5281 tcaggcccat ggccagtgcc tgagcgacaa aggcgtccgc caggcgcttt tcttcagcgg
     5341 gagtcagttt caggtgcgtc atagtggcct ccgggcgtct caggtttccc gaacagttta
     5401 accgcaggtc ctctcctcat gccagttagc tttcagatgt gtctatacca tctgaaatgt
     5461 aagtgtgatg aatgtcttaa ataataaaat ttgttgccat gagaaatttt cgggaaaaga
     5521 cgcgatctgc ttacaggtgg ctccgggcgc ttttttgtgc ctgaagatga gaactaatct
     5581 catatattga cacctgaaaa cgggaggagt aaggtaataa ttatactgtg tatatgtaca
     5641 gtgtgcgccg ggagaccggt tagagatcaa ggggtgaaag tccccgacca ttgaaggacc
     5701 agcaatccac aaggtccccg agtcatgcgt tgcataccgc gaggtatggg gcgaagcgtt
     5761 gacaggggtg ttgacaggcc agccattgag ccacgaaatg tatattaaat taccgggtgc
     5821 cgacgttgta ctgttaacgg aaggcaacat catagggtgc gacactgcga gtgccacatg
     5881 gacccggcgg ggtctgagac cctggcatgt caatacgatc tctacgcggg aaccgggaga
     5941 tctcccctct gaccatctgc cagtgtcgga gatggcccgc accgggaaga cgaggagtca
     6001 tagccggtga tgtacggaga ggagaagtcg gactcgctca tagtagcggc gaagcaggcg
     6061 aacaacccga aaggagcgga gtcagtggag cgaaggagcg gggccaaggg gaacgcggaa
     6121 cagccacaca tgcgccggac acagagccgg gaaagcatgt cacagaggct gtcacgcgtg
     6181 cgggaagctg cgaagcagcg gaagaaagaa cggtttacag cattgttcca cctgctgaca
     6241 gtcgaagcac tggaagccgc attcctctcc ctgagcagga aagcggccgc cggagtggat
     6301 ggcatcaggt ggatggacta cgccggaaac atgaagaaca acataacaga tctgcaccgg
     6361 aggctacatc agggcagcta cagggcgcag cccggcaggc gtcactacat cccaaaagcg
     6421 gatggaaaac aacgcccgct cggcatcgcc tcgctggagg acaagatcgt ccagtatgcg
     6481 ctggtgaaaa tcctgaacgc agtctatgaa aacgacttta tgggggttct catacgggtt
     6541 cagacccggg cgaagccagc acgatgcact ggacgcactg gccacagggc tggtacgcac
     6601 taacgtaaac tgggtactgg atgccgacat cagtcagttc ttcgacaggg tgagccacga
     6661 atggctgatc aggttcacag agcatcggat cggcgaccgg agggtaatca ggctcatacg
     6721 taagtggctc acagccggga cgtcggagga gggtcaatgg cgagcaacgg aggaaggcac
     6781 cccacagggt gcggtcatct caccgctgct ggcaaacata tacctccact acgtcttcga
     6841 tctgtgggcg catcagtggc gacgtcgcta tgccacaggc aatgtggtaa tggtcagata
     6901 cgccgatgac atcgtcatcg ggttcgacaa acgatacgat gcccggcgct tccgtatagc
     6961 catgcagcgc agactgaggg agttcggact cacggttcac ccggagaaaa cccgtctgat
     7021 ggagttcggc cgcttcgctg ccgaaaaccg tgccatcagg ggaaaaaggc aaaccagaaa
     7081 cgttcaactt cctcgggttc acgcacatca gcgggaaaga tcgcaacggc aggttcatgc
     7141 tgatacgaaa gacccgccgg gatcggatga cggcaactct gaaagccatc aaagacggtc
     7201 tgcgaaggcg ctggcattac tcaatccccg aacagggaaa atggctcagg agagtggttc
     7261 agggatacct gaactatcac tcggtaccgg gcaacttccc caccatgcag aagttcagga
     7321 cacacgtaac aaacctctgg cgccgggcgc tcaggcgcag gagccagaag gatgatacga
     7381 cctggacgaa agcaaacaaa ctggcagccg catggctacc aagggttcgg gttcttcatc
     7441 catggcctgt ggagcggttc accgccagac acccgaggca ggagcccggt gcgtaaatcg
     7501 cgcacgccgg gatctgtgcg gggggtatcc ggtaacgggt atccctaccg cgacatgttg
     7561 gctttaattt attgttttaa atgtcaaaga ggaaaacggt atgagtggtg gagacggtcg
     7621 aggtccgggt aattcaggtc tgggacataa tggtggtcag gccagtggga atgtgaacgg
     7681 tacgtctggt aaaggtggcc cttcatcagg tggtggtacg gatccaaaca gcgggccggg
     7741 ctggggtacg acgcatacgc cgaatggaga tattcataac tataatcccg gggggagttt
     7801 ggtaacggcg ggagtaaacc cggtggtaat ggtggtaaca gcggcaatca tagcggtagc
     7861 tctggtggcg gacagtcttc ggccactgcg atggccttcg gtctgcctgc cctggctact
     7921 ccgggggctg aaggactggc tttatcagtt tccggcgatg cgttgtcggc cgccgttgct
     7981 gatgtgctgg ctgccctgaa ggggccgttt aagtttggtc tgtgggggat tgcgatctac
     8041 ggtgtgctgc cttctgagat tgcaaaagat gatccgaaaa tgatgtcaaa aattatgacg
     8101 tcattaccgg ccgatgcggt gacggagact ccggcaagta ctttaccact ggaccaggcg
     8161 acggttcgtg tcagacaacg ggttgtggat gtggtgaagg atgagcggca gcatattgcg
     8221 gttgtcgcag gtcggccaat gagtgtccct gtggtggatg cgaaaccgac aaaacgtccg
     8281 ggggtattca gtgtgtcgat tccgggtctc ccgtctctgc aggtgagcgt accgaaaggt
     8341 gttccgacag cgaaagcccc gccaaaaggc attgttgctg aaaaaggtga ttcacgtccg
     8401 gctggtttta cagccggtgg taactcccgt gaggccgtta ttcgtttccc gaaagagacc
     8461 ggacagaagc cggtttatgt gtcggtgaca gatgttctta ccccggcaca ggtaaaacag
     8521 cgtcaggagg aagaaaagcg tcgccagcag gcatgggacg ccgctcatcc ggaagagggg
     8581 ctgaaaagag actatgataa agcgaaagct gagctggatg ccgaagataa aaatattgcg
     8641 accttaaaca gccgcattgc atcgacagag aaggcgctcc ccggtgcaag ggctgctgtt
     8701 caggaagccg ataaaaaggt aaaagaggca gaggcaaata aagatgattt tgtgacttat
     8761 aacccgcctc atgaatatgg ctccgggtgg caggatcagg ttcgctatct tgataaggat
     8821 attcagaatc agaatgagaa attaaaagcg gctcaggcat ctttaaacgc aatgaatgaa
     8881 tccttatcca gagataaggc tgcacttacc ggggcgatgg agagccggaa acaaaaggag
     8941 aaaaaagcga aggatgcaga aaataagtta aatgaggaaa agaacaagcc tcgcaagggg
     9001 actaaagact acggccatga ttatcatcca gtacctaaaa cagaagacat aaagggactt
     9061 ggagagttaa agcgaggtga tcctaaaaca cctaaacaag gtggtggtgg taagcgggcc
     9121 cgatggtatg gcgataaaaa acgtaaaatt tatgaatggg attcccagca cggtgagctt
     9181 gaagggtatc gtgccagtga tggcgaacac ctaggcgcat ttgatcccaa aacgggtaag
     9241 caggttaaag ggccagatcc aaaacggaac attaaaaaaa atatctttga gaggtaaata
     9301 tggggcttaa attacgtttg acatggtttg ataagaaaac tgaagagttt aaaggggaag
     9361 agtattctaa agactttggt gacgatggtt ctgtcattga aagcttggga atgcctttaa
     9421 aggataatat taataatggt gagtttgatt tgaagaaaga atgggttcct ttactacagc
     9481 cattttttaa aaatcaaata aaacctgatg tggataattg ttatatagct tttgattatc
     9541 gggacggtaa ctggtaacaa aaaattatca aggatgattt gaaatactga cttccggtgt
     9601 tcagggatga atgccggagt ctttaaatac agggaaagta tatgaaaaag gtaaagacta
     9661 tttttctttt tatattgatt gttgctggct ttcttctggc cgcatgtcag gcaaattata
     9721 tccgggatgt tcagggcgga acggtggcac catcgtcctc ctctgaactg acggggatcg
     9781 cggttcagta gaaaagatca aaggatcttc ttgagatcct ttttttctgc gcgtaatctt
     9841 ttgccctgta aacgaaaaaa ccacctgggg aggtggtttg atcgaaggtt aagtcagttg
     9901 gggaactgct taaccgtggt aactggcttt cgcagagcac agcaaccaaa tctgtccttc
     9961 cagtgtagcc ggactttggc gcacacttca agagcaaccg cgtgtttagc taaacaaatc
    10021 ctctgcgaac tcccagttac caatggctgc tgccagtggc gttttgcgtg ctttcccggg
    10081 ttggactcaa gtgaacagtt accggataag gcgcagcagt cgggctgaac ggggagttct
    10141 tgcttacagc ccagcttgga gcgaacgacc tacaccgagc cgagatacca gtgtgtgagc
    10201 tatgagaaag cgccacactt cccgcaaggg agaacggcgg acaggtatcc ggtaaacggc
    10261 agggtcggaa caggagagcg caagagggag cgacctaccg gaaacggtgg ggatctttaa
    10321 gtcctgtcgg gtttcgcccg tactgtcaga ttcatggttg agcctcacgg ctcccacaga
    10381 tgcaccgaaa aagcgtctgt ttatgtgaac tctggcagga gggcggagcc tatggaaaaa
    10441 cgccaccggc gcggccctgc cgttttgcct cacatgttag tcccctgctt atccacggaa
    10501 tctgtgggta actttgtatg tgtccgcagc gcccgccgca gtctcacgcc cggagcgtag
    10561 cgaccgagtg agcgaggagg cgcaatttcc ccggcacctg caagacggtc accggacgcg
    10621 ctgatgtggg atattgtccc ctgattaagt ctttctattc cctgacgatc aattatcagg
    10681 ataggtgaac catgtcggtt tttcgctgaa cattttacgt taacctatct ctgttgcttt
    10741 tttctccttg cggagaaatg caagtcatcc ccgctggggc gtggctgact tcaggggaaa
    10801 agaccttgct tacgctggct ggacgccacc gacgcacggt cttttcccct ctttctggct
    10861 ctgtccggct ggacgccggc cacgccagaa attcacccgg cccccgtcag gctcacgcct
    10921 gaccacccac aaaaatccac ggtgctggac gcacctgacg aagcagcaaa gctgctcctg
    10981 attttgcggg tggtcagccg ctcgctatgg cgaactctga cgggggccgg aacaccggaa
    11041 aagaccgcac tggggtgccg ccttttcctc tcacacgctg gggcgtgctc gttgttcctc
    11101 cggggctgcg ccttttccgc atggggcgga aagaggctgg cctccgcggt gaaagctgaa
    11161 cgcaatcacc acggacgtga ccgccgccgc catgccttgg ggcatgtccg cggcttgtgc
    11221 agcgggggct gcgcatcacg ccggtaaacc cgtcgtctga aggagagaga ttgcatgttt
    11281 aatacggatt cgcttgcctg gcagtggcat atcccggagc tggcccggca gatttacccg
    11341 tgggtcagct ggctgtaccg ggagtattac agtctggccg gtttttttct ggttatcggc
    11401 ctgtttttcg gtctggctga actctgggcc ggccgaatgc gttttgtggg gctgagccat
    11461 aaggcgcggc gggagtatgc cgatcgctat aagcgcgata ataaccggac tgtgccattt
    11521 tcggtgctgg cctcgctgga ttcacccggg cggatggtca gggcacggcg acatgtctgg
    11581 aactacgcgt actggctgac cggcgctgcc ggtctggccc ttctgggggg gctggttgtc
    11641 gccgtgttta tcgagagctg gggagaaacc gtcctgcgcc cggacctcta tgcgaacgca
    11701 gattattacc tgctgcagcc ggctaacctg ttcgggatag cctggtgtgc cggagggctt
    11761 gtcgccggcg tccttctggc gcggctgctg gcgttcctgc tgcttgatgg tcattttgcg
    11821 gccgctgacg aggcggtgaa cgcgaaactg aatcaggaga gccggcgcag cagccagcgg
    11881 accggagaaa tgacagacgt ccgccacctg catttcgggg agccggtacc ggttaacgcg
    11941 ctggccgatt tttccacgga gcaggcccgg aaacagcagg cggtgtttct gggtaaggat
    12001 gagcagggcc agccggtgct ggtccctcgt gatacctggc gcaagaccaa tattcagatc
    12061 ctcggcctgc ccgggagcgg caagagcgcg atggccacca acgcgctcat tcgctgcgta
    12121 cgcgatttcg gggacgctgt ggtgtacttc gaccccaaag gggacgcgtg ggcgccgcac
    12181 gtcttccggg cgcactgccc ggacttcacc ctgctggatc tgcggccggg gaaaccggcg
    12241 cagctgaatc tgttccgcga tctcgaccag tacgccctga agaatctgct ggttgccggg
    12301 tttaacctga gtgagaccgg cgacgtggcg gaccactacc gcatcagcga gcagaaagcg
    12361 gcgaagctga ttgcggagca gttcccgcag ggggcaaaca ttcagcaggt gctggcggcg
    12421 gcgtacgcgt tgccggaggc cctgaaaaag gacgtgaagg ggctgatcac caagctggag
    12481 aacgtggccg acctgagcgt cctgcagacg gacagcggta tcgatgtggc ggggataatc
    12541 aacggcggcg gctgcctgta cgtcatcggc tcgatggacg atgaggcggt gatccgggtg
    12601 cagaagatgc tgtttgcccg ctgcgcgcaa atcatcattg cgcgggatga gttccggagg
    12661 tggccgcacg cgagcatcat gctcgatgag attaaatatc tgctgtcgaa gtacgtgctg
    12721 aacgcgctgg ggacgctgcg cagccgggac tgcaacctgc tgctcgcgca ccagtcgctg
    12781 ggcgacttcg gtcagtgcgg gcaggatctg cccgctgatt ttgtgaaaac cacggtactg
    12841 gataacacgc cgatccgctg gttctatcgc gcggccagcc aggagtccgc gcagtgggcg
    12901 gcgggccaga ccggggagat ccgggtggac gtggagcgcc gccgggccag ccgggaggcg
    12961 gggaacgtgg agcacatcag cggcgacagc ttcatccaga aggaggcgcg gccgctgttt
    13021 gacgtgaaca ccctgcaaca cctgcctgac gggttcgcgg tgatgaccgg gctgggcgtg
    13081 gcgcggctgg cgttcagcag cccgctgcgg gttgagcgcc gggaaatttc gctgaaaacc
    13141 ttcccggtgc tggcgaaaac ggacccgctg gcggagtacc tgcctccggc cgacggcggc
    13201 ggaccaaaag cggatgatga ttttgcgggg ctttactgat gacactggag cagtacaacg
    13261 tcagccacgc gaagcggcag gcgcggaacg cggagaaaac acggctgacc ctgcgctggc
    13321 tgcgggaaga gctgtgttcc acggcggagc tggttgcgcg acggctgggg attgcggcgg
    13381 tacagccggt ttaccgcttc ctggacagtc tggtggcgaa agggctgctg gtccgggcga
    13441 aatacccggt tgacggccgt caggtcagcg tgtgggggct gacgccgcac ggggtggcgt
    13501 tctcgttcga cgaggacgag ccgctgacgg acgttattcc gtttcagccg tcaagggtgt
    13561 cggcggcgca gctgccgcac cggctggccg tgcagtccct gcgcctctcc atggagggcc
    13621 ggggggccac cggctggcgg tacctgcacc gtatggccct gaaagggatg aaagtgccgg
    13681 acgcgctggc ggagctggac ggcagaacgg tggcatttga ggtagagcgc accgtcaaga
    13741 gccgcaggcg gtatcaggaa gtggtgtccg ggtatctgtt caaccgccgg gcgaacggca
    13801 tcgatgaaat ctggtacatc tgccctgacc ggccgacgct tgtccgggta cagcgggcga
    13861 ttctggcggt ggatgaaatc gtgaatccac agaccggcga ggcccgcaaa acggtggagc
    13921 tggaccggga gaggctgttc gcgtgcttta aatttatgac aacggagtga gggattatgg
    13981 cgctgtacat ggtatttatt gaggacgtgg aagacaaaga cggcgagcgc tgcattatgc
    14041 caaccagcga gcatctggaa gacatggtgg tgctcgcctg gcagaccggg gcgtatgttt
    14101 tctgttttgt cgaccgggcc cagcatctgg cgatgatgaa atccatcggg atgtatgacg
    14161 agcggctcaa cagcgacgaa aaagccacgt actttttcac cggtgaaaat ccgcaatggg
    14221 aacgggacaa acccacagga atgaagctgt gtgattacct ctatcgaaag gtggagcggt
    14281 tcgccatcga gaacggtgtg caggtggttg atgccgggaa gtgctcaccg gagcagatta
    14341 acgcgatgat tgaggtggtc agcgagcggc acggggaaag cgcggtgaac gagaagctga
    14401 aagcggagct gatgcgggaa tataacagcc gctattttaa cgtgccggtg cctgaactgc
    14461 cggaggacaa acccgcccgc cggtggtggc cgttcggcaa aaaataacgc cagcaccggc
    14521 atggccggtg ctgttattct tccccgagct tatcccgcat cacctgccag agtgtttccg
    14581 catcctcgtg aagccgttcg cacatgtcgg ccggggtatc catgtccagc tcgttcagct
    14641 tttccagcaa cagcagcgac tgatccttaa tgaatttagc catattgagg gcagtttttt
    14701 cctgcttcgt catgttctcc attcccttcg gtaagttctc agctaaacca gccggaccag
    14761 aagcgttttt tcttctgtgt cagttctgtt gtcaatctgt ccacttcggc ctggagtttc
    14821 cggcgctcat catcgtgctg gcggcgttct tcttcccggg atgttttatc ttccagcatc
    14881 agggtgacag cctgccggag atcggccagt tccttttgca ttgccagaag ctgttcctgt
    14941 gggaaatttt tttgtgtatt ttcacggtgt gaaatgccgg gaatttgttt ctcagggata
    15001 ttcacatttc cgtatacacg gatcagttct gacacatcca cgacagggtt gtttttcccg
    15061 tcacgtgaca cggtaacctt tccctgtttt acatgattgt atagcgttct tctggtaatg
    15121 cccgcggctt gtgctgcctg tgaaaggttg agcaatgttt tcgccactgt atacccctga
    15181 ttttatcggg tgtgaaaggt gtgtaatttc tcacggtaaa tgtatcgctg aattttaccc
    15241 gtttttccgt tcaggatgtg gttttctgac gcgctgcgct tgtcaaaccg gcgacggcca
    15301 cgcaatgaat tgcgcccccg tcatcggtta ttagaggctg tctgcccccg gatacccgga
    15361 ttctttctga tgcctgacgg tgacgatcac aatctggtcc atttcccggt cgtggcggta
    15421 gagcatcaca tagccactgt cgccaaaccc gatcaccagt tccttatatt ccagcggcag
    15481 aaacggcacc gggcggccaa tgtctggcaa tgttttcagt tgctggatag cccggacgat
    15541 cacctcacct ccttttctgg ctgccagccg atttttggtt ttgagaaagt cctgaaggcg
    15601 ttgtaaatcg cgctgtgcca gcgcggaaat cgttacctgt ggcatggcgg agcatcctgc
    15661 tcgttctcag ttccccaggt acttatccag gcttccgctt cttccgcagt aaggtgcaga
    15721 cccgtttcct gatagtgctg ccatgcggcc tgtccgtccc gcaggtactg gctgcgcttc
    15781 tcttcccggt cgatgtattc ggtgattgcc tccagcatta gcgcgtgcgc tgagcggtgc
    15841 cggtcatcgg ccagcgtttt cagccggtcc ttaagttctt catcgagcct gatggatgtt
    15901 gctgatgaca taaaagcccc tttgtagtca tatgtattac acatgactac tttaatccgt
    15961 ggcggcgcta tttgccagaa atacggcttt tgctgcccat ttttcagctt cgcttccact
    16021 aatcagggct gctacaggct cactcatcat ccaggactat tgcagcctgc gggttaaagg
    16081 acctgttact ggcggcaacc atcatcattg agcttttggg tggtgactgg tcgcggatcc
    16141 tgtaagccgt catttttcag actgaattca aaatttataa cctgtcgcat tgccgggtgc
    16201 cctgcgggat atagccagtg cctcattgcc gtcagcgttt cccgaaaaaa aaggtgacag
    16261 ccggtaagcg acacgttgtc cactcgtcca tcgtccagaa tatcaaacgt ggcggtcacc
    16321 tgaccttcga tgcgttttgc tgcggcctgt accgggtagg ttggctgcag tgtggttacg
    16381 ggttttagtg gtatcgcatg taccggagtg aggaacatgg ccgccagcac tgtcagagta
    16441 aaagctttca tggtctgaaa tccagagggg cgtttttgaa tatttgccag gtattttcat
    16501 ccggtgccgg cggaattttg gcgtgggtaa cggctgatat tgctgcttta cagagtttcg
    16561 gatctcctcc ttcagcaatg gcgctgttca gagtgccatc acgttgtatg gatatccgca
    16621 cggtgcacat ttttcccgca taggcctctg gttcaaacat ctgcatttca acagcggtct
    16681 tgatggccgc agcgtagcta ctgattttag atgacttatc cagagtataa attttcggcg
    16741 gctgggtggt ggaatgctta caggccgtca ggagtaaggg gctgcacaat gccagcagga
    16801 taaagggtat taaacgcatc gggttgatga cctgtcagta aaaaatgtta catgtatatt
    16861 tgtcactctt tacggccacg ttcatttaca taaacacggc ttatcgtatc gtttttacac
    16921 caaacggccc gccatgcagt tgcgtgcata ggcatgcagc gggttacaat ttaccgggcg
    16981 cgtttccggc ggttttccgg gtggtttgtt gcctgtttta tcccgtagcc gccggaaacg
    17041 ccctcagacc gtctgagcgg tgcgggcaat gcgacgttat ggtaaatacc ccttaccggc
    17101 ggcgctgtgg ctgccaggtg aaggtggttt ccgtagcctc gtatttctcc cgacgcattt
    17161 cctgcgcccg cctggcttca cgttcgtcct gaatggcacg aagcaccctt tcccgcacct
    17221 gttgttttac cgcctttggc agcgttttgt tccctttcag gcccatggcc agtgcctgag
    17281 cgacaaaggc gtccgccagg cgcttttctt cagcgggagt cagtttcagg tgcgtcatag
    17341 tggcctccgg gcgtctcagg tttcccgaac agtttaaccg caggtcctct cctcatgcca
    17401 gttagctttc agatgtgtct ataccatctg aaatgtaagt gtgatgaatg tcttaaataa
    17461 taaaatttgt tgccatgaga aattttcggg aaaagacgcg atctgcttac aggtggctcc
    17521 gggcgctttt ttgtgcctga agatgagaac taatctcata tattgacacc tgaaaacggg
    17581 aggagtaagg taataattat actgtgtata tgtacagtgt gcgccgggag accggttaga
    17641 gatcaagggg tgaaagtccc cgaccattga aggaccagca atccacaagg tccccgagtc
    17701 atgcgttgca taccgcgagg tatggggcga agcgttgaca ggggtgttga caggccagcc
    17761 attgagccac gaaatgtata ttaaattacc gggtgccgac gttgtactgt taacggaagg
    17821 caacatcata gggtgcgaca ctgcgagtgc cacatggacc cggcggggtc tgagaccctg
    17881 gcatgtcaat acgatctcta cgcgggaacc gggagatctc cccctctgac catctgccag
    17941 tgtcggagat ggcccgcacc gggaagacga ggagtcatag ccggtgatgt acggagagga
    18001 gaagtcggac tcgctcatag tagcggcgaa gcaggcgaac aacccgaaag gagcggagtc
    18061 agtggagcga aggagcgggg ccaaggggaa cgcggaacag ccacacatgc gccggacaca
    18121 gagccgggaa agcatgtcac agaggctgtc acgcgtgcgg gaagctgcga agcagcggaa
    18181 gaaagaacgg tttacagcat tgttccacct gctgacagtc gaagcactgg aagccgcatt
    18241 cctctccctg agcaggaaag cggccgccgg agtggatggc atcaggtgga tggactacgc
    18301 cggaaacatg aagaacaaca taacagatct gcaccggagg ctacatcagg gcagctacag
    18361 ggcgcagccc ggcaggcgtc actacatccc aaaagcggat ggaaaacaac gcccgctcgg
    18421 catcgcctcg ctggaggaca agatcgtcca gtatgcgctg gtgaaaatcc tgaacgcagt
    18481 ctatgaaaac gactttatgg gggttctcat acgggttcag acccgggcga agccagcacg
    18541 atgcactgga cgcactggcc acagggctgg tacgcactaa cgtaaactgg gtactggatg
    18601 ccgacatcag tcagttcttc gacagggtga gccacgaatg gctgatcagg ttcacagagc
    18661 atcggatcgg cgaccggagg gtaatcaggc tcatacgtaa gtggctcaca gccgggacgt
    18721 cggaggaggg tcaatggcga gcaacggagg aaggcacccc acagggtgcg gtcatctcac
    18781 cgctgctggc aaacatatac ctccactacg tcttcgatct gtgggcgcat cagtggcgac
    18841 gtcgctatgc cacaggcaat gtggtaatgg tcagatacgc cgatgacatc gtcatcgggt
    18901 tcgacaaacg atacgatgcc cggcgcttcc gtatagccat gcagcgcaga ctgagggagt
    18961 tcggactcac ggttcacccg gagaaaaccc gtctgatgga gttcggccgc ttcgctgccg
    19021 aaaaccgtgc catcagggga aaaaggcaaa ccagaaacgt tcaacttcct cgggttcacg
    19081 cacatcagcg ggaaagatcg caacggcagg ttcatgctga tacgaaagac ccgccgggat
    19141 cggatgacgg caactctgaa agccatcaaa gacggtctgc gaaggcgctg gcattactca
    19201 atccccgaac agggaaaatg gctcaggaga gtggttcagg gatacctgaa ctatcactcg
    19261 gtaccgggca acttccccac catgcagaag ttcaggacac acgtaacaaa cctctggcgc
    19321 cgggcgctca ggcgcaggag ccagaaggat gatacgacct ggacgaaagc aaacaaactg
    19381 gcagccgcat ggctaccaag ggttcgggtt cttcatccat ggcctgtgga gcggttcacc
    19441 gccagacacc cgaggcagga gcccggtgcg taaatcgcgc acgccgggat ctgtgcgggg
    19501 ggtatccggt aacgggtatc cctaccgcga catgttggct ttaatttatt gttttaaatg
    19561 tcaaagagga aaacggtatg agtggtggag acggtcgagg tccgggtaat tcaggtctgg
    19621 gacataatgg tggtcaggcc agtgggaatg tgaacggtac gtctggtaaa ggtggccctt
    19681 catcaggtgg tggtacggat ccaaacagcg ggccgggctg gggtacgacg catacgccga
    19741 atggagatat tcataactat aatccggggg agtttggtaa cggcgggagt aaacccggtg
    19801 gtaatggtgg taacagcggc aatcatagcg gtagctctgg tggcggacag tcttcggcca
    19861 ctgcgatggc cttcggtctg cctgccctgg ctactccggg ggctgaagga ctggctttat
    19921 cagtttccgg cgatgcgttg tcggccgccg ttgctgatgt gctggctgcc ctgaaggggc
    19981 cgtttaagtt tggtctgtgg gggattgcga tctacggtgt gctgccttct gagattgcaa
    20041 aagatgatcc gaaaatgatg tcaaaaatta tgacgtcatt accggccgat gcggtgacgg
    20101 agactccggc aagtacttta ccactggacc aggcgacggt tcgtgtcaga caacgggttg
    20161 tggatgtggt gaaggatgag cggcagcata ttgcggttgt cgcaggtcgg ccaatgagtg
    20221 tccctgtggt ggatgcgaaa ccgacaaaac gtccgggggt attcagtgtg tcgattccgg
    20281 gtctcccgtc tctgcaggtg agcgtaccga aaggtgttcc gacagcgaaa gccccgccaa
    20341 aaggcattgt tgctgaaaaa ggtgattcac gtccggctgg ttttacagcc ggtggtaact
    20401 cccgtgaggc cgttattcgt ttcccgaaag agaccggaca gaagccggtt tatgtgtcgg
    20461 tgacagatgt tcttaccccg gcacaggtaa aacagcgtca ggaggaagaa aagcgtcgcc
    20521 agcaggcatg ggacgccgct catccggaag aggggctgaa aagagactat gataaagcga
    20581 aagctgagct ggatgccgaa gataaaaata ttgcgacctt aaacagccgc attgcatcga
    20641 cagagaaggc gctccccggt gcaagggctg ctgttcagga agccgataaa aaggtaaaag
    20701 aggcagaggc aaataaagat gattttgtga cttataaccc gcctcatgaa tatggctccg
    20761 ggtggcagga tcaggttcgc tatcttgata aggatattca gaatcagaat gagaaattaa
    20821 aagcggctca ggcatcttta aacgcaatga atgaatcctt atccagagat aaggctgcac
    20881 ttaccggggc gatggagagc cggaaacaaa aggagaaaaa agcgaaggat gcagaaaata
    20941 agttaaatga ggaaaagaac aagcctcgca aggggactaa agactacggc catgattatc
    21001 atccagtacc taaaacagaa gacataaagg gacttggaga gttaaagcga ggtgatccta
    21061 aaacacctaa acaaggtggt ggtggtaagc gggcccgatg gtatggcgat aaaaaacgta
    21121 aaatttatga atgggattcc cagcacggtg agcttgaagg gtatcgtgcc agtgatggcg
    21181 aacacctagg cgcatttgat cccaaaacgg gtaagcaggt taaagggcca gatccaaaac
    21241 ggaacattaa aaaatatctt tgagaggtaa atatggggct taaattacgt ttgacatggt
    21301 ttgataagaa aactgaagag tttaaagggg aagagtattc taaagacttt ggtgacgatg
    21361 gttctgtcat tgaaagcttg ggaatgcctt taaaggataa tattaataat ggtgagtttg
    21421 atttgaagaa agaatgggtt cctttactac agccattttt taaaaatcaa ataaaacctg
    21481 atgtggataa ttgttatata gcttttgatt atcgggacgg taactggtaa caaaaaatta
    21541 tcaaggatga tttgaaatac tgacttccgg tgttcaggga tgaatgccgg agtctttaaa
    21601 tacagggaaa gtatatgaaa aaggtaaaga ctatttttct ttttatattg attgttgctg
    21661 gctttcttct ggccgcatgt caggcaaatt atatccggga tgttcagggc ggaacggtgg
    21721 caccatcgtc ctcctctgaa ctgacgggga tcgcggttca gtagaaaaga tcaaaggatc
    21781 ttcttgagat cctttttttc tgcgcgtaat cttttgccct gtaaacgaaa aaaccacctg
    21841 gggaggtggt ttgatcgaag gttaagtcag ttggggaact gcttaaccgt ggtaactggc
    21901 tttcgcagag cacagcaacc aaatctgtcc ttccagtgta gccggacttt ggcgcacact
    21961 tcaagagcaa ccgcgtgttt agctaaacaa atcctctgcg aactcccagt taccaatggc
    22021 tgctgccagt ggcgttttgc gtgctttccc gggttggact caagtgaaca gttaccggat
    22081 aaggcgcagc agtcgggctg aacggggagt tcttgcttac agcccagctt ggagcgaacg
    22141 acctacaccg agccgagata ccagtgtgtg agctatgaga aagcgccaca cttcccgcaa
    22201 gggagaacgg cggacaggta tccggtaaac ggcagggtcg gaacaggaga gcgcaagagg
    22261 gagcgaccta ccggaaacgg tggggatctt taagtcctgt cgggtttcgc ccgtactgtc
    22321 agattcatgg ttgagcctca cggctcccac agatgcaccg aaaaagcgtc tgtttatgtg
    22381 aactctggca ggagggcgga gcctatggaa aaacgccacc ggcgcggccc tgccgttttg
    22441 cctcacatgt tagtcccctg cttatccacg gaatctgtgg gtaactttgt atgtgtccgc
    22501 agcgcccgcc gcagtctcac gcccggagcg tagcgaccga gtgagcgagg aggcgcaatt
    22561 tccccggcac ctgcaagacg gtcaccggac gcgctgatgt gggatattgt cccctgatta
    22621 agtctttcta ttccctgacg atcaattatc aggataggtg aaccatgtcg gtttttcgct
    22681 gaacatttta cgttaaccta tctctgttgc ttttttctcc ttgcggagaa atgcaagtca
    22741 tccccgctgg ggcgtggctg acttcagggg aaaagacctt gcttacgctg gctggacgcc
    22801 accgacgcac ggtcttttcc cctctttctg gctctgtccg gctggacgcc ggccacgcca
    22861 gaaattcacc cggcccccgt caggctcacg cctgaccacc cacaaaaatc cacggtgctg
    22921 gacgcacctg acgaagcagc aaagctgctc ctgattttgc gggtggtcag ccgctcgcta
    22981 tggcgaactc tgacgggggc cggaacaccg gaaaagaccg cactggggtg ccgccttttc
    23041 ctctcacacg ctggggcgtg ctcgttgttc ctccggggct gcgccttttc cgcatggggc
    23101 ggaaagaggc tggcctccgc ggtgaaagct gaacgcaatc accacggacg tgaccgccgc
    23161 cgccatgcct tggggcatgt ccgcggcttg tgcagcgggg gctgcgcatc acgccggtaa
    23221 acccgtcgtc tgaaggagag agattgcatg tttaatacgg attcgcttgc ctggcagtgg
    23281 catatcccgg agctggcccg gcagatttac ccgtgggtca gctggctgta ccgggagtat
    23341 tacagtctgg ccggtttttt tctggttatc ggcctgtttt tcggtctggc tgaactctgg
    23401 gccggccgaa tgcgttttgt ggggctgagc cataaggcgc ggcgggagta tgccgatcgc
    23461 tataagcgcg ataataaccg gactgtgcca ttttcggtgc tggcctcgct ggattcaccc
    23521 gggcggatgg tcagggcacg gcgacatgtc tggaactacg cgtactggct gaccggcgct
    23581 gccggtctgg cccttctggg ggggctggtt gtcgccgtgt ttatcgagag ctgggggaga
    23641 aaccgtcctg cgcccggacc tctatgcgaa cgcagattat tacctgctgc agccggctaa
    23701 cctgttcggg atagcctggt gtgccggagg gcttgtcgcc ggcgtccttc tggcgcggct
    23761 gctggcgttc ctgctgcttg atggtcattt tgcggccgct gacgaggcgg tgaacgcgaa
    23821 actgaatcag gagagccggc gcagcagcca gcggaccgga gaaatgacag acgtccgcca
    23881 cctgcatttc ggggagccgg taccggttaa cgcgctggcc gattttttcc acggagcagg
    23941 cccggaaaca gcaggcg
//
