LOCUS       NZ_CP084010            18220 bp    DNA     circular CON 09-NOV-2023
DEFINITION  Staphylococcus epidermidis strain NBRC 113846 plasmid unnamed2,
            complete sequence.
ACCESSION   NZ_CP084010
VERSION     NZ_CP084010.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN21163584
            Assembly: GCF_020181395.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus epidermidis
  ORGANISM  Staphylococcus epidermidis
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 18220)
  AUTHORS   Tourlousse,D.M., Narita,K., Miura,T., Furukawa,M., Shimamura,M.,
            Sekiguchi,Y. and Kawasaki,H.
  TITLE     Characterization and demonstration of mock communities as control
            reagents for accurate human microbiome community measurements
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 18220)
  AUTHORS   Tourlousse,D.M., Narita,K., Miura,T., Furukawa,M., Shimamura,M.,
            Sekiguchi,Y. and Kawasaki,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-SEP-2021) Biomedical Research Institute, National
            Institute of Advanced Industrial Science and Technology, Biomedical
            Research Institute, AIST Tsukuba Central 6, 1-1-1 Higashi, Tsukuba,
            Ibaraki 305-8566, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Flye v. 2.8.3; Racon v. 1.4.20; Medaka v. 1.2.2;
            Pilon v. 1.23
            Assembly Name                     :: Sepi_113846
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 362.0x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/09/2023 06:58:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,399
            CDSs (total)                      :: 2,315
            Genes (coding)                    :: 2,253
            CDSs (with protein)               :: 2,253
            Genes (RNA)                       :: 84
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 36 of 62
            Pseudo Genes (incomplete)         :: 32 of 62
            Pseudo Genes (internal stop)      :: 25 of 62
            Pseudo Genes (multiple problems)  :: 25 of 62
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP084010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..18220
                     /organism="Staphylococcus epidermidis"
                     /mol_type="genomic DNA"
                     /strain="NBRC 113846"
                     /isolation_source="human skin"
                     /host="Homo sapiens"
                     /db_xref="taxon:1282"
                     /plasmid="unnamed2"
                     /geo_loc_name="Japan"
                     /collection_date="2018"
     gene            join(17494..18220,1..245)
                     /locus_tag="LCR03_RS11830"
                     /old_locus_tag="LCR03_11830"
     CDS             join(17494..18220,1..245)
                     /locus_tag="LCR03_RS11830"
                     /old_locus_tag="LCR03_11830"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_049391782.1"
                     /translation="MSNFNIKEIQKEKFYQLPKVFFTNPKYTKLSNDAKITWSILRDRL
                     DLSIRNNWVDENGDIFFIYTNEKLKSILNISSPNKLSKIKKELTEADLFNQIRVGLNKP
                     NKLYIKKPEVTEADVYYISQQENDIEQHNNTDVSLSYVQKYDNDTSRNINMIHHDISKE
                     YTNDTDLSNTDYIETENNDTYDMNDTYNNQTNHNHSDHTNHQQSEFNNDALKFQVLEEL
                     PQQIKDYLSNFEIKEIRIIKSVLLKGKKSFNNTFNTYYRLEDVEFELVSVLKRFKAMLL
                     QKNETVEAMQGYLMKSIKAELEEIHTLNMRRQNMKKHNIFNQ"
                     /name="replication initiator protein A"
     gene            <262..558
                     /locus_tag="LCR03_RS11835"
                     /old_locus_tag="LCR03_11835"
                     /pseudo=""
     CDS             <262..558
                     /locus_tag="LCR03_RS11835"
                     /old_locus_tag="LCR03_11835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001568503.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(1318..1992)
                     /locus_tag="LCR03_RS11840"
                     /old_locus_tag="LCR03_11840"
     CDS             complement(1318..1992)
                     /locus_tag="LCR03_RS11840"
                     /old_locus_tag="LCR03_11840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_225088350.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKIVTDQAPSTKAAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVKKTRYQNINTAKSTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            2008..2427
                     /locus_tag="LCR03_RS11845"
                     /old_locus_tag="LCR03_11845"
     CDS             2008..2427
                     /locus_tag="LCR03_RS11845"
                     /old_locus_tag="LCR03_11845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002494373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_070858627.1"
                     /translation="MLKLYYKFNFATEPDLAYIRSMNVTEYIRQTAVGNRIKPTVIEYP
                     KEQITMDDSNSKNNTNNLYKVIEHLEEDNEALKSDRDALRQRHDQLEDDIEQYKRENEI
                     FHRLLEHFDSTAFMNFNTYRDDRPLKKEIKRLKEH"
                     /name="hypothetical protein"
     gene            complement(3018..3392)
                     /locus_tag="LCR03_RS11850"
                     /old_locus_tag="LCR03_11850"
     CDS             complement(3018..3392)
                     /locus_tag="LCR03_RS11850"
                     /old_locus_tag="LCR03_11850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002467994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002494371.1"
                     /translation="MKKIVYILGTIIVLGFCYFYVNLIFFDSWTRYSAEKEINNYISNH
                     DTKKLKEISANNKTYQLLKHAKHVTIKGDTDNQGGGHIGYFTSTINGKEGALFVHLNFG
                     LFPEIPKVTKLEVFDKNIYE"
                     /name="hypothetical protein"
     gene            4241..4402
                     /locus_tag="LCR03_RS11855"
                     /old_locus_tag="LCR03_11855"
     CDS             4241..4402
                     /locus_tag="LCR03_RS11855"
                     /old_locus_tag="LCR03_11855"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_162153024.1"
                     /translation="MNEREQRQKLNITLPPKLITNLDKVKTKYGINKSKQIENLISKYL
                     NEEYGNLE"
                     /name="hypothetical protein"
     gene            4422..4808
                     /locus_tag="LCR03_RS11860"
                     /old_locus_tag="LCR03_11860"
     CDS             4422..4808
                     /locus_tag="LCR03_RS11860"
                     /old_locus_tag="LCR03_11860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002494369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002494369.1"
                     /translation="MKKAIFSIIISLILVLTVTGCSNSSKEKPIKKSALEINPTSKAVN
                     ITINKKENNKPEKIGKVYRYKNNNAKEITNDGIKKDTKDTLIWKGVANKYDNVKDLLGE
                     SILYEVKYKNGDIKKFERKIKYTE"
                     /name="hypothetical protein"
     gene            complement(4968..5417)
                     /locus_tag="LCR03_RS11865"
                     /old_locus_tag="LCR03_11865"
     CDS             complement(4968..5417)
                     /locus_tag="LCR03_RS11865"
                     /old_locus_tag="LCR03_11865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002494368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002494368.1"
                     /translation="MKKLLSVFIASLLVLTGLSFSSINQGNTASAKTKYKTTITYKGQK
                     YVYVGHYKHHFSKKEVKKVVKFSKGVHSGNKLVSAASKLSKNGYVKASSAIYKAFDFGL
                     KNELKGSYFYTAAKKGTGVTISYDMYTATTGPNHTIAKNFKHSYN"
                     /name="hypothetical protein"
     gene            complement(5616..5795)
                     /locus_tag="LCR03_RS12040"
     CDS             complement(5616..5795)
                     /locus_tag="LCR03_RS12040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001829546.1"
                     /translation="MKSIVHFICLFIIFCIFGYVIDLIFFKEINIFLILESAFILSLLI
                     MPILKIVKEIEIEK"
                     /name="hypothetical protein"
     gene            complement(6029..6424)
                     /locus_tag="LCR03_RS11870"
                     /old_locus_tag="LCR03_11870"
     CDS             complement(6029..6424)
                     /locus_tag="LCR03_RS11870"
                     /old_locus_tag="LCR03_11870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002502726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="WP_002494367.1"
                     /translation="MKRKYKITGIIFIVLLIVLTLIFSIVHHYANVQKHEEAKLKQKVH
                     HIFKQKGWEDKVKEEKNIFTFNTGDNDLQVTFKDEPYNTYTYSIDEDNKVYGNAVLKDE
                     YDKDFDSKKKYKEYLRKMHFEEKYDLK"
                     /name="DUF3139 domain-containing protein"
     gene            6528..6896
                     /locus_tag="LCR03_RS11875"
                     /old_locus_tag="LCR03_11875"
     CDS             6528..6896
                     /locus_tag="LCR03_RS11875"
                     /old_locus_tag="LCR03_11875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002503834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="WP_002494366.1"
                     /translation="MKKILKILITSIIVIIITLTVWTFSVITYQEHKSEKIIDHVIERK
                     GWDKKIKNEKMSFNIMMGYAEKDIAFKDQPYSEYEYNVTPAPAPWTDDKEYKVWGETDL
                     QKKDSYYKYLLESEPYRK"
                     /name="DUF3139 domain-containing protein"
     gene            7026..7391
                     /locus_tag="LCR03_RS11880"
                     /old_locus_tag="LCR03_11880"
     CDS             7026..7391
                     /locus_tag="LCR03_RS11880"
                     /old_locus_tag="LCR03_11880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020368092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002494365.1"
                     /translation="MKWLKIIILILSLVPIEFIGLFTDYQTGLLIGYIPFIIVAILISR
                     SIFKFGLKNNISIIISRCIGTFLSWECVHWFMNIYDSSDYFKPLTTDIFALFLGAIHFI
                     VIMLIYLVIYGFSHRNN"
                     /name="hypothetical protein"
     gene            7721..7816
                     /locus_tag="LCR03_RS11885"
                     /old_locus_tag="LCR03_11885"
     CDS             7721..7816
                     /locus_tag="LCR03_RS11885"
                     /old_locus_tag="LCR03_11885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002501808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_002501808.1"
                     /translation="MLAIFVYITVSIFIECCVALFKFWLEQRNKK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            8048..8659
                     /locus_tag="LCR03_RS11890"
                     /old_locus_tag="LCR03_11890"
     CDS             8048..8659
                     /locus_tag="LCR03_RS11890"
                     /old_locus_tag="LCR03_11890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_032603908.1"
                     /translation="MNKSKVAEIRKQKSLTQENLAEKAYVTVRTIQRMEAGEEVSSETL
                     KSVSNALDVTVNELFESISSSDKEEEIMEISKEQQKQFNYRKSELFTIKLITFSFIFVF
                     LGLFGIFVGELNGLEQNIYGIIWLFTLFLILAIMHYFLNVFISKKLDKKYPMTIGMKNR
                     VSNRKSEPVKNGWDFMARYWWIVFPIGGFLSWLIPELTGK"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(8707..9565)
                     /locus_tag="LCR03_RS11895"
                     /old_locus_tag="LCR03_11895"
                     /pseudo=""
     CDS             complement(8707..9565)
                     /locus_tag="LCR03_RS11895"
                     /old_locus_tag="LCR03_11895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440631.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /name="RepB family plasmid replication initiator protein"
     gene            complement(10011..10394)
                     /locus_tag="LCR03_RS11900"
                     /old_locus_tag="LCR03_11900"
     CDS             complement(10011..10394)
                     /locus_tag="LCR03_RS11900"
                     /old_locus_tag="LCR03_11900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="WP_002485672.1"
                     /translation="MKLYVNEIIRTNNFEDDDMMNKILGMWDSFYKNNDDYKGEVYAVY
                     HDYESDYKGDYSLALCTEDISADKFFEVDFADSTEYKCSGKDEIINVWKRIWGDEEENK
                     IQRSYYIDCEEYKKDGSVVIHLF"
                     /name="effector binding domain-containing protein"
     gene            complement(11049..>11308)
                     /locus_tag="LCR03_RS11905"
                     /old_locus_tag="LCR03_11905"
                     /pseudo=""
     CDS             complement(11049..>11308)
                     /locus_tag="LCR03_RS11905"
                     /old_locus_tag="LCR03_11905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001568503.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            12260..12355
                     /locus_tag="LCR03_RS11910"
                     /old_locus_tag="LCR03_11910"
     CDS             12260..12355
                     /locus_tag="LCR03_RS11910"
                     /old_locus_tag="LCR03_11910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_011276848.1"
                     /translation="MLEILVHITTTVISGCIIALFTHWLRNRKDK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            12809..13420
                     /locus_tag="LCR03_RS11915"
                     /old_locus_tag="LCR03_11915"
     CDS             12809..13420
                     /locus_tag="LCR03_RS11915"
                     /old_locus_tag="LCR03_11915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002487382.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000635275.1"
                     /translation="MIVGYARVSSVDQNLERQLENLKTFGAEKIFTEKQSGQSIENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEVINTVNYLKEKEVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDNDDLF"
                     /name="recombinase family protein"
     gene            complement(13570..14427)
                     /locus_tag="LCR03_RS11920"
                     /old_locus_tag="LCR03_11920"
     CDS             complement(13570..14427)
                     /locus_tag="LCR03_RS11920"
                     /old_locus_tag="LCR03_11920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002499202.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="WP_000162894.1"
                     /translation="MTKKMVIISFGRILLIIIGALITAYGLESILIPNNVSDGGVTGIS
                     IVGSTLFGLPLGILIGIINLPFIWLGYKQIGRKFAIFSIIGILSLSIFTSIMHHVPTII
                     EGDSLLITVVGGVVIGLGMGLALRNGGALDGIDMLAVLLSRKLPFGTSDLILFLNTFVF
                     ILVSTVFGFKGAILSALAYFIASKVIHIIEEGLSGSKTFKIITKDYDIMNKEIKERLGR
                     YCTFTKVTIDEENNSFVEISCVINKLEEQKLKEIINDVDPDAFIAIYDTAEVKAGNMKK
                     SDIY"
                     /name="YitT family protein"
     gene            complement(14676..15806)
                     /locus_tag="LCR03_RS11925"
                     /old_locus_tag="LCR03_11925"
     CDS             complement(14676..15806)
                     /locus_tag="LCR03_RS11925"
                     /old_locus_tag="LCR03_11925"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002456255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="WP_002456255.1"
                     /translation="MQSKKIFDYVIPLAEDGFEVNSELEMSIKKYSKGIDKSSPFFKGD
                     GNTVKNGDIVKQPQLTKTLKGIKNNGPNYFYDKLAKHLTTELNGQIDKTDFNNYKSKQK
                     KPSETKYLNTHVYSSSNPLGGGLMLQGLKLDEMLNNGQSDEQYLNSVLSGRDLMYSNRD
                     IVNAKTNFSQEYLSNMYISNKYNNQNTSDSISDNSVKKTSTLHFVVVDKQGQMTSTTNT
                     LSGYFGSGKYMDEGFYMNNSMTNFSDNKDSNNYHAKNTVPRSYISPTIIVGPDYYMGIG
                     SPGGNKIPTILNEVIIDYLRGNGSLQDSIYKPRFYNDGNTVHFEKGMNKKYLDILQNQG
                     YNIKEEKDNPNFGSVQAGIYHIKNKKTEIANDVGTR"
                     /name="gamma-glutamyltransferase"
     gene            15801..16200
                     /locus_tag="LCR03_RS11930"
                     /old_locus_tag="LCR03_11930"
                     /pseudo=""
     CDS             15801..16200
                     /locus_tag="LCR03_RS11930"
                     /old_locus_tag="LCR03_11930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002499214.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /name="VOC family protein"
     gene            complement(16320..17000)
                     /locus_tag="LCR03_RS11935"
                     /old_locus_tag="LCR03_11935"
     CDS             complement(16320..17000)
                     /locus_tag="LCR03_RS11935"
                     /old_locus_tag="LCR03_11935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_002503026.1"
                     /translation="MKSMKEIADELNVTKMTVYNNAKKANVKFQKIDNVNYLTSEDEII
                     VINRIRKNQNKNDDFESEKKEEPNNDNLVKDETIKQLYNQIDIYKEQSNRDKEQINTLN
                     RLLENQQVLALESNKKIKKLEDQLEEERRLNYSFDTSVNERQNVNVQEATFTGESKDTD
                     QQQEWEQPTEVQHKDIPEEKENENLNEEPSTIDDKQFEEIDNEYEDKEEKPPKKGFWSR
                     LFGN"
                     /name="DUF536 domain-containing protein"
     Typing          complement(8806..9565)
                     /name="rep_cluster_1442"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="87.927"
                     /coverage="88.0"
                     /evalue="0.0"
     Typing          17495..18220
                     /name="rep_cluster_1110"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="94.223"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gtgttttact caaagggaaa aaatctttta acaacacatt taatacatat tatcgtttag
       61 aagatgtcga atttgaactt gtcagtgttt taaaacgttt taaagccatg ctgctacaaa
      121 agaatgaaac cgttgaagct atgcaaggat atttaatgaa atcgattaaa gctgaacttg
      181 aagaaataca cacacttaat atgcgtcgtc aaaacatgaa aaaacataat atctttaacc
      241 aataatttag ataatcttat agcaatcaaa gagacatcaa agtattcggt taagtcctct
      301 gattatttaa caggagaccg tgaaaaagat gcagagattg ttaatgattt agagcaaggt
      361 ttatacagaa aacgcatgtt gagttatggt gtattgctta agaaaaaaca taaacttttg
      421 aatttagatg atgccgaaga tggtaactta attcaaacaa gtgatgaaga aaaaacgaca
      481 gaagaagaac aaaaagctca ttcaattacg gcaatttgga atttcgaaaa gcaaaattac
      541 ttcttaaaaa atttgtaatg ctgtctaaat ataataatat tctttgtaag aatttcagaa
      601 aaatatatac catatggaga ccgaatgtat accaaatgga gacaaattta tgtctccatt
      661 tggtatacat tttttatttt tggtatccat ttgggagaca tttttgattt tgggtagcta
      721 ttcggtagct tttgtgtagc cgttcgggag tcatataaca atttttatcg cataaatagg
      781 aatcccattt gacactgtca aatcaatatt ttgcacagaa atggctactg aatggagaca
      841 tttggagaca tttctgtgca ggattcctct tatgctcttg aatttgttat agtttcatta
      901 tacaccatag atacagcgag ttcatacctg aaaagacgat ttaacgagaa gaatataaca
      961 acaataatta ggttaacttt atgaatttcc agatcgattt aatacgaaag acaaagaaaa
     1021 taaaaacaaa aaaagactcg atttaataac cgagtcgaag aaaaatattg atagaacgac
     1081 gttattattt tcaatgattc cttaaaaaat gttaaaaaag ttaggcgaat aattacttaa
     1141 tttacttcat tttttgactt catacatata ttcattatta taattttaac gagtttttta
     1201 gttactgtaa gtgaactatt cccatgttta aatttaatat ttctatctaa gatttgaatg
     1261 gttctgttgc aaagtaaaaa atatagctaa tcactaatat atcatgtcag tgttcgttta
     1321 acttgctagc atgatgctaa tttcgtggca tggagaaaat ccgtagatct gaagagacct
     1381 acggttcttt ttatatagag cgtaaataca ttcaatacct tttaaagtac tttttgccgt
     1441 attgatattt tgatatcttg tcttttttac tttaatatga cggtgatctt gctcaatgag
     1501 gttattcaga tatttcgatg tacaatgaca gtcaggttta agtttaaaag ctttaattac
     1561 tttagccatt gctgccttcg ttgaaggtgc ctgatctgta actatctttt gaggcttacc
     1621 aaattgttta atgagacgtt tgataaacgc atatgctgaa tgattatctc gttgcttacg
     1681 caaccaaata tctaatgtat gtccctctgt atcaatggca cgatataaat agctccattt
     1741 tccttttatt ttgatatacg tttcatcaat acgccatttg taataagctt ttttatgctt
     1801 tttcttccaa atttgatata aaattggggc atattcttga acccaacggt agatcgttga
     1861 atgatgaacg tttacaccac gttctcttaa tatttcagat atatcacgat agctcaatgc
     1921 atatcttaga tagtagccaa cggctacagt gataacatcc ttgttaaatt gtttatatct
     1981 gaaatagttc atacagaaga ctcctttttg ttaaaattat attataaatt caactttgca
     2041 acagaaccag atttagccta catacgtagt atgaatgtca cagaatatat acgccaaaca
     2101 gctgtgggta atcggattaa accgacggtg attgaatatc caaaagagca aataacgatg
     2161 gatgattcta attctaagaa taatacgaat aatttgtata aagttattga acatctagaa
     2221 gaagacaacg aagcactcaa atcagacaga gacgcacttc gacaacgtca tgaccaactt
     2281 gaagatgata tagaacaata caaaagggag aatgagatat ttcatcgctt gttagagcac
     2341 tttgatagta ctgcatttat gaattttaat acgtatcgtg atgatagacc attaaaaaaa
     2401 gaaattaaac gattgaaaga acattaaaaa ggctactcaa aaaatgttta tcgtaagaaa
     2461 tggggcaaaa agaagacatt aatgctttct attttttgtt gtaccaataa ttaataatac
     2521 aaaaaataga aaacctaata aataaaatat tttttctcct aaaggatttc caatgatatt
     2581 ttcattcaat cctataatca aacaaactat aaaaataaca ataataatgc ctgaataaat
     2641 cttatttttt aataacataa aattaacctt tcttttctat aaaatctggg atactaccaa
     2701 taattaaccc caataaaaat acaaatctga aaaaatatga atatagtcta aaaaaggaaa
     2761 tcaaatatta atttcacaat tagcaataat ataaatgcta tcactgtact atttaacaaa
     2821 atatacatga tttttttgta tatttcatga ctattttttc tcttaaaaaa atcataaaaa
     2881 cactccagat tcttagccag atttctaacg attatcatag catagaagct taatgctata
     2941 tggacgtaat tagctatatt tttctaactt tgcaacagaa ccagaataac taacacgaaa
     3001 aatgagtagc aattatgcta ctcataaata tttttatcaa aaacttccaa cttggttact
     3061 ttaggaattt caggaaacaa accaaaatta agatgtacaa aaagcgctcc ttctttacca
     3121 ttaatcgtac tagtaaaata ccctatatga cctccacctt gattatctgt atctcctttt
     3181 attgtcacat gtttagcatg tttcaaaagt tgatatgttt tattattcgc ggatatttct
     3241 tttagtttct ttgtatcatg atttgaaata taattattta tttctttttc agcagaataa
     3301 cgtgtccaac tatcaaaaaa aattaaattt acataaaaat aacaaaagcc taaaactata
     3361 atagtaccaa gtatataaac tatttttttc atttaaagac tccttatctc ctcaaaatat
     3421 ttaagttttt atggtaaatt aaagtggttc tgttgcaaag tcagaaacat aaggttatat
     3481 acttatcttt ctgactttgc aacagaaccc tattttaact atagttttaa attgctttat
     3541 tgacgttgaa cctccgaatc tttaacaatc cctaaactta tcgaatcgtc ggcttaatag
     3601 cttacgctat gccgacattc ggcttcaagt ttagttaagg gttcttctca acatcaataa
     3661 attttctcgg tataaatgcg tgtgatatga ttaatgtagt actccctttc atttaataca
     3721 tcaaaaacta ttcttcagac tactcatttt ttgagtagtc tttttatttt gcattttaag
     3781 ccctttctag aacattttat taaaaaatga ctaaaaactt ttttgttcaa cagataggct
     3841 ataaatcatt ttaaaatttc tttctcaaca ctttcagaaa ggaaaatata ttttttatct
     3901 caattgttct tcttagaaaa aagctaaaac ctgaaaaagt aggtatataa tgtaactttt
     3961 gtattttaaa gagcataagg aaatccatta ccgcttaagg tagtattcag catagctgaa
     4021 ggactatctt accatttgct ttgctcattt attcttagtt gaaaactata gggctttttt
     4081 gagaggaaaa aattgttttt cttttatcgt ttgtcgtaat tataatagct ccataaagta
     4141 aaaaacaaac tatactatac ttcttttatg ggtacaaact tgactttgta cgcatgtaat
     4201 gctactttat acgcataaat aaaaggagag tgttgtgggt ttgaatgaaa gagaacaaag
     4261 acaaaagtta aatattactc ttcctcctaa attaataact aatttagata aagttaaaac
     4321 aaaatatggt attaataaat ctaaacaaat tgaaaattta atatcaaaat atttaaatga
     4381 agaatatggt aatcttgaat aagcaaaaaa ggatgattag aatgaaaaaa gcaatattta
     4441 gtattattat ttctcttatt ttagttctaa ctgttactgg atgtagtaat agttctaaag
     4501 aaaaaccaat taaaaaaagt gcattagaaa ttaatcctac aagtaaagct gttaatatta
     4561 caataaataa aaaagaaaat aacaaacctg aaaaaattgg gaaagtgtat cgatataaaa
     4621 ataacaatgc aaaagaaatt actaatgacg gtattaaaaa agatactaaa gatacattga
     4681 tttggaaagg tgtagcaaac aaatacgaca atgtaaaaga tttattagga gaaagtattc
     4741 tttatgaagt taaatataaa aatggggata taaaaaaatt cgagagaaaa attaaatata
     4801 ctgaataaaa ttgaaagtag tgatgataat ggaaaatatt ttaagaataa tagctgaaat
     4861 attatctaat atctatgaat tcataaatta tggtctaaaa ttcaaccgtt caaaaaagct
     4921 tgaaaataaa tgtgagggga aggattaatc cttcccctca catttattta attataacta
     4981 tgtttaaaat tcttagctat agtatggttc ggacctgttg ttgcagtata catatcataa
     5041 gaaattgtta cgcctgtacc ttttttagct gctgtgtaaa aatagctacc ttttaattca
     5101 tttttcaatc caaaatcaaa ggctttataa atagccgagg atgctttaac ataaccattt
     5161 ttactaagtt tactagcagc agatactaat ttgtttcctg aatgaactcc tttagaaaat
     5221 ttaactactt ttttaacttc ttttttagaa aaatggtgtt tataatgacc aacatataca
     5281 tatttttgac ctttgtaagt tatagttgtt ttatattttg ttttagcact cgcagtatta
     5341 ccttgattaa ttgaagaaaa agataatccg gttaaaacta ataaacttgc aataaaaact
     5401 gaaagtaact ttttcataaa aagacctcct gtaaaatatt tatatgttta aatatgactt
     5461 tatcatataa attaagttat aactacttta attaaaaaaa ttaacactat atatattttt
     5521 ttaaaattca gttaataaag atggatcttt attaactgaa ttttagtagc ctatttttat
     5581 taaacattaa gtatagaaaa tggtatttac cagttctatt tttcaatttc tatctctttt
     5641 acaatcttta atatcggcat gattagtaat gataaaataa aggctgattc taaaatcaga
     5701 aaaatattta tttctttaaa aaatattaaa tctatcacat atccaaaaat acaaaatatg
     5761 ataaagaggc aaataaaatg aacaattgat ttcaatgcta atactccttt ttgctttcta
     5821 agctatttta aactttatac aggcttttca tttaatatca tataggtaat tttagtatat
     5881 ttcatattaa agacgcgcat atgcttttaa aatggcatat ataagcctcc aaattacaag
     5941 atagaaaacg aatcataaaa aagcattaaa caaattgaaa gaacactaaa aagcaagcga
     6001 ctatcaatta tcgtagtcgc ttgctttttt atttcagatc atatttttct tcaaaatgca
     6061 tttttcttaa atattctttg tacttttttt tactatcaaa atctttatca tattcatctt
     6121 tcaaaacagc atttccatat actttattgt cttcatcaat agaatatgta tacgtattat
     6181 aaggctcatc tttaaaagtg acttgtaaat cattatctcc agtattgaac gtaaatatat
     6241 ttttttcttc tttaacttta tcttcccaac ctttttgttt gaaaatatgg tgaacttttt
     6301 gttttagttt agcttcttca tgtttttgaa cattagcata atggtgcact atactaaaaa
     6361 ttaatgttaa aacgataaga agaacgataa agatgatacc tgtaatttta tattttcttt
     6421 tcatattagt ctccttaagc aaatttattt aattaatatt ttgtaaaatt aaatacaata
     6481 atacatattt atcataaaaa ttattaaaaa agaggaatta tacaaaaatg aagaaaatct
     6541 taaaaatatt aataacttct attattgtta tcattattac cttaacagtt tggactttta
     6601 gtgtgattac ttatcaggaa cacaagagtg agaaaatcat cgatcacgtt atagaacgta
     6661 agggttggga taaaaaaata aaaaatgaaa aaatgagttt taatattatg atgggatatg
     6721 ctgaaaaaga tattgctttt aaagatcaac catatagtga gtatgagtat aacgtgacac
     6781 cagcaccagc accatggaca gatgataaag aatataaggt atggggggaa acagatttac
     6841 aaaagaaaga ctcctattat aaatatcttt tagaatcaga accttacaga aaataatata
     6901 aatgtataac ataataaaaa atagagatca ttcatctatc acttaaagac agcgtagact
     6961 tttacctaat tatattaata aaatgatatt gaaggaaaaa taatattgaa aagagaaatt
     7021 ttaaaatgaa atggttaaaa atcattatat taattttatc tttagttcca atagaattta
     7081 tcggattatt tactgattat caaacaggtt tattaatagg ttacatccca tttataatag
     7141 ttgctatatt aataagtaga tctattttta aattcggctt aaaaaataat ataagtatta
     7201 taataagtag atgtattgga acatttcttt cttgggaatg tgttcattgg tttatgaata
     7261 tttacgattc atcagattat tttaaacctc ttactacaga tattttcgca ttatttttag
     7321 gagctattca tttcatagtt attatgctta tatatttagt tatctatggt ttttctcatc
     7381 gcaataatta actattatgt tacttatatt acaggacaca aagattaatt taacaatgtt
     7441 tgtgtttttg agtatttata caaaggcact acccataata gttaattatg ttaactcatc
     7501 aaagaggctt aaacgctgtg aaatcaacgt ttaagccttt tctttatgat tatcgtttat
     7561 gcatctttta tacatcattg atctcatgcg ttttcataag ttttcataaa gagaaatttt
     7621 ttatttttat gcaatgtata tcacgtagct cacatggtat attatatgaa gtcgtctttt
     7681 cctcagacgt caatttgacg tagagagggg gtgcgatgaa atgttagcga tatttgttta
     7741 tataacagta tctattttta tagagtgctg tgttgcgttg tttaaatttt ggctagaaca
     7801 acgtaataaa aaataagacg gcatagtcaa caccgaaaaa accccagcct attgcagtag
     7861 gctggggttt ggtgcgtaaa tgctagcaat atttgttaat ttcagtatat cctttcttat
     7921 gctttttgta aaattagata tatactttct tttaagaata taattttgaa gtaactgtcg
     7981 tttcattgtc gtccatctgt cggtaatttt tcgtgttcat tttttagttg aggagtagtt
     8041 tatgagtatg aacaaatcaa aagttgcaga aattagaaaa caaaaatcgt taactcaaga
     8101 aaatttagca gaaaaggctt atgtaacagt aagaacaatt caaagaatgg aggctggaga
     8161 agaagttagt agtgaaacac ttaaaagtgt ctcaaacgca ttagatgtga cagtcaatga
     8221 actattcgaa tctatctcgt cttctgataa ggaggaggaa ataatggaaa tatctaaaga
     8281 acaacaaaag cagtttaatt atcgtaaaag tgaacttttt actattaaat taataacatt
     8341 tagttttatt tttgtgtttt taggactatt tggaatcttt gtaggtgagt taaacggttt
     8401 agaacaaaat atttacggaa tcatttggct ttttactttg tttttgatct tagcaataat
     8461 gcattatttt ttaaatgttt ttatttcaaa aaaattagat aaaaaatatc ctatgactat
     8521 tggaatgaaa aatagagtat ctaatagaaa aagtgaacct gtaaaaaatg gctgggattt
     8581 tatggctaga tattggtgga ttgtctttcc tattggaggt tttctaagtt ggttaatacc
     8641 tgaattaaca ggaaaataaa atacaaaata aaagatcttt agcacacttg ctaaagatct
     8701 tttatcttaa tcttcccaat caacttgaag ttgttttaag aatgcttttc gctctttttc
     8761 taattgtgga tcatactcac tttttaattt ttttttcata agtacgttct tctaatcatc
     8821 tcggcgtttt ttcacgactg atatattgtc tttgtttacc tacattagtc atttgaggtt
     8881 gtcgcttgtt atgaatgcgt ttctcagcgt caaacgtaaa ctctaaccac tcaattttac
     8941 gtcctttttt tgctttaatt ttattgatat taagattatt aaaaattgaa gcaagttcat
     9001 taattatagg ctttaataca cgtttggtta tatcattcat ttgataagtt ttaggtatat
     9061 ctagacgatt tttaaaatca gctatattta tttttacata accagtatgt ttatattgtt
     9121 taagcaatct aaacatattt ttagcgtaag tagatttaag atgcgtcatt tcttttaatt
     9181 caaatttagt aaaatcagct gttatagaat ttaaaatatg ttttaaatca ggattaacac
     9241 taatagataa acattcttcg tctaaatcta ctttgtatga agtaaataaa acaaattttt
     9301 caaaagacct accattacgt tctacatatg ttagattcaa cattttatcg tatacgtgct
     9361 ctaaatcatt aataaagcgt tcttgagaac gcgtgtagta gttacttaaa tattttaatt
     9421 cttcaaaagg aataattact tttctcgtat cttgctcttt aagtttattg cataatgtaa
     9481 agaataaatc tacttcagta cttgtaaagc gtcttaatga gactaaattc atttcatttc
     9541 tatatactac tgtttcacca gacataaaaa aacacctctc ttaatatata agtgacttaa
     9601 atttaaaaac gtccctttta gcatttcaaa tccattgtca ctctaaggct caaatgacgc
     9661 ctaaaaaggt tttaaaaaga tttataaaaa gatattaaaa agttcggggc aatttgcccc
     9721 tcacaaattc aaaagacaaa aaggaaacca accacatttg tggttggttt ttattattta
     9781 aaaaagtaat aagtgatata actttaaagc aattggaata aagcattaaa aaatagccac
     9841 tcaatttgtg agtagctatg tgttgggcga agaactatta catgttaaaa gaattaatga
     9901 tgtttgagga taatgctata tttttacttt aacacttatt taattacagt gcattcaaaa
     9961 gtatttaacg atgagatttt ttggcttttt tgaaactcgt ttcaaaaaac ctaaaaaaga
    10021 tgtataacaa ctgacccatc ttttttatat tcttcgcaat caatataata acttctttga
    10081 atcttatttt cttcttcatc tccccaaata cgtttccata cgtttataat ttcatctttt
    10141 ccagagcact tatattcagt actatcagca aagtcaactt cgaaaaattt atctgccgaa
    10201 atatcttctg tacacaaagc taatgaataa tcgcctttat aatccgattc ataatcatga
    10261 taaactgcat atacttcccc tttataatca tcattatttt tataaaaact atcccacata
    10321 cctaaaattt tattcatcat atcatcatct tcgaagttat ttgttctgat aatttcgtta
    10381 acgtacaact tcataaaaaa accccttttc tttttaattt actaaaaaca ttgcattatt
    10441 ccaattgctc aacgtcaata aattttctcg gcataaatgc atgtgatatg attaatgtag
    10501 tactcccttt catttaatac atcaaaaact attcttcaga ctactcgaaa aatgagtagt
    10561 ctttttattt tgcattttaa gccctttcta ggacatttta ttattccacg taataataaa
    10621 agactaaaaa cttttttcat tcaacagaga agctataaat cgctttaaaa tttctttctc
    10681 aaaactttta gaaagaaaaa tgtatttttt atctcgattg ctcttctcag caaaaagcta
    10741 aagcctaaaa aataggtgta aaatataact ttaacatttt aaattaaatt aaagagcata
    10801 agaggaatcc tgcacaaaaa gtctccattc ggtagccatt tttgttaaaa gcattgattt
    10861 gacagtgtca aataggattc ccatttatgc gctgaaattt gttatatgga gaccgaatgt
    10921 atactcaaaa gatactgaat agatcccaaa aattaaaaat agctaccgaa tggagacata
    10981 aaaatggagc catttggtat acatttttat gaaatcctta caaaaaatat tattatattt
    11041 agacagcatt acaaattttt taagagataa ttttgttttc gaagtgtcca attgctgtaa
    11101 ttgaatgtgt tttttcttta tcaattgttt gaattaaatt accatcttca gcgttatcta
    11161 aatttaaaag tttatgtttt tatttaagta attacatcga aacttagtat acgttttcga
    11221 tataaaattc attctaagtc attaacaatt tctgcatttt ttcagggggt cttgttaaat
    11281 aatcgagcga aataatggaa tattttgatt agtttttgta ggatttatgc gccgtttttt
    11341 catatgttag acaagcgtaa aaacaaaagt agagcacaca tttatgctaa gaaattttaa
    11401 taatgttgtg aggctctcta actaaatttt aagacgaatg gcgtatagtg tgagcgatga
    11461 agtcgacaat tctacaagtt tgggaattgt taagagtttc aaaaatcaat gttaatacat
    11521 taatttcaat tctaattctg tactcatttt acagttaata aaatgagtat tattaggcta
    11581 ataatactta ttatgagatt aattaagttt ataaaagtct tagagatttt cttgtcattg
    11641 tattctagac ttttatatag aagcatgtaa tatataaaca aatttgctgt aaacattccg
    11701 aatattgaag ctaagattcc aaaatgaatc tccataaaaa tagtttgaat aaaaaatatg
    11761 agaatgaaat tataaaaaat aataagattt cataaattaa cagaatcatg atttttctcc
    11821 tataaattaa agaaaacata aatcataatc aattttttaa tgttcaaagc gaaaattatt
    11881 aggaaatctg ttaaatgaaa tgacgcaaat ttaagagtat ataggatcaa ggaaaagcat
    11941 attagacttt aaaaggtgct aaaaagtatt attggaaagt aagtataaaa tcaataattc
    12001 tattacaaat gcaatagtca ttagtaaact agtaaattta tttacttata gtgatgtatt
    12061 taattactat aataaacttg aaatatactt ataaagtatc tcttttgcct ctagatatca
    12121 tagaaatggt tctggatctc actatcatta cataaaatga cttatcggaa gtacatatgc
    12181 ttcaaaagat acagatggta taataatgga gtcgcctatc tctcaggcgt caatttgacg
    12241 tagggaggag gtgttattca tgttggaaat ccttgttcac atcacgacca cagtcatcag
    12301 tggttgtatt attgcgttat ttacgcattg gctgcgtaat cgcaaagaca aataggcgac
    12361 aatagccaca cctacaaaaa tcccctcact atttacggta gtgaggggat tggtgtatcc
    12421 atgctggatt ccttgttaag tgcattataa catcatagtg tagaggaatg caaaattagt
    12481 atctatatag gaggatgaaa taaaatagaa agttttatag gatttctaac agtttttttc
    12541 tttgctttaa tgatcatcac tttttctttt acagctatac tatatataat aaaaggactt
    12601 tataatgaac aagcaacagg tgctttatta gctagtacaa tatttatgat tatatttatt
    12661 ttttctgctc ttttctattt atatttagtg aaaagataat gtaaaaatgt taatcataag
    12721 tacaccctaa tcatacaaaa tgaattgttg aaattacagc aattaaaatg tatgattagg
    12781 gtgtatatta attatgaggt gaaactaaat gattgtgggc tatgcgcggg tatcatcagt
    12841 agatcaaaat ttagaaagac aacttgaaaa tttaaaaaca tttggtgctg aaaaaatttt
    12901 tacagaaaaa caatcaggtc aatctataga aaacagaccc gtctttcaag aagcattgaa
    12961 ctttgtgaga atgggagatc gttttgtcgt ggaatcaatt gatcgtttag gtcgtaatta
    13021 tgatgaagtc attaataccg ttaattatct taaagagaaa gaagtacaat tgatgattac
    13081 cagtctacca atgatgaatg aagtcattgg taatccatta ttagataaat ttatgaaaga
    13141 tttaattata cagatattag caatggtttc agaacaagaa agaaatgaaa gtaaacgtcg
    13201 acaagctcaa gggattcaag ttgcgaaaga gaaaggcgta tataaaggac gacctttatt
    13261 atattctccc aatgcgaaag atcctcaaaa acgtgttatc tatcatcgtg ttgtagaaat
    13321 gttagaggaa ggcaaagcga ttagtaaaat tgcgaaagaa gtgaatatta caagacaaac
    13381 tgtttataga attaaacacg ataacgatga tttgttttaa taaacggttt ttcaatgcaa
    13441 atgagagctt ctcacagcgt ctgaaaactt atggtgatca attattctga gattttaata
    13501 ttaaaacaag aaaagagaga accaataaaa agctacctaa taactggtag ctttttattt
    13561 atcgtaattt taatatatat ctgatttttt catatttcca gccttaactt ctgctgtatc
    13621 atatattgcg ataaatgcgt ctgggtctac atcatttata atttctttaa gtttttgttc
    13681 ttcgagttta ttaataacac aagaaatttc tacaaatgaa ttattttctt catcaatagt
    13741 cacttttgta aatgtgcaat accttcccag tctttcttta atttctttat tcataatgtc
    13801 ataatctttt gtaataattt taaacgtttt cgaaccactt agtccttctt caataatatg
    13861 tataactttt gaagcaataa aatatgcgag cgctgataaa atggcacctt taaagccaaa
    13921 aacagtagaa acaagtataa atacgaatgt attgagaaat aaaattaaat cacttgttcc
    13981 gaaaggtaac tttctagata ataaaacggc taacatatct ataccatcta atgccccacc
    14041 atttctaagg gcaagaccca tgcctaatcc aataacaact ccaccaacta cagtaataag
    14101 tagtgaatca ccttcaataa ttgttggtac atgatgcata atcgaagtga atatagataa
    14161 tgataagata cctattattg aaaatatagc aaacttacgt ccgatttgtt tataacctaa
    14221 ccatataaat ggtaaattga ttattcctat taatattcct aaaggtaaac caaacaaagt
    14281 ggaacctaca atactaatcc ctgtgactcc tccgtcagaa acgttatttg ggattaatat
    14341 agattccaaa ccatatgctg taataagtgc cccaattata ataagtaaaa tcctgccgaa
    14401 tgatataatc accatttttt ttgtcatttt tgaactccta tttttattat taaaaagtct
    14461 tcacctatat tataacttgt tttatcaatt taatgaaatt ggtgttaatg attgatatca
    14521 tattttttta aacaaaattc taaaaaagat aatttaatgt ttaatcagcg tctaatactc
    14581 aaagtaaata aatgaaaaat ttcccaaggc atttacaaat atattaaaat acaccaatct
    14641 ctaaaatttt gaagattggt gtattttaaa tcagtttatc tggttcctac atcatttgca
    14701 atttcagttt ttttattttt aatatgataa atacctgctt gaacacttcc aaaattagga
    14761 ttatcttttt cttctttaat attgtaacct tgattttgaa gtatatctaa atacttttta
    14821 ttcatccctt tttcaaaatg tactgtatta ccatcattat aaaatctagg tttatatata
    14881 ctatcttgca acgatccatt acctctaagg taatcaataa ttacttcatt aagaatagtt
    14941 ggtattttat ttccaccagg gctaccaatt cccatatagt agtctggtcc aactataatt
    15001 gttggagata tatatgacct tggcacagta tttttagcat gataattgtt actatcttta
    15061 ttatcagaga agttcgtcat ggaattattc atatagaatc cttcatccat atatttacca
    15121 gacccaaagt atcctgatag tgtatttgtc gtactcgtca tttgaccttg tttgtcaacg
    15181 actacaaagt gtaaagtact cgttttctta acactattat cgctaataga gtcagatgta
    15241 ttttgattgt tatatttatt acttatatac atatttgaaa ggtattcttg agagaagttc
    15301 gttttagcat taacgatatc tctattactg tacattaaat ctcttcctga taaaacacta
    15361 tttaagtatt gttcatcact ttgaccatta ttaagcatct catctaattt taaaccttgt
    15421 agcattaatc cgccacctaa gggattagat gatgaataaa catgggtatt taaatacttt
    15481 gtttcacttg gttttttctg ttttgattta taattattaa aatcagtttt atcaatctgg
    15541 ccgtttaatt ctgtagttag atgctttgca agtttatcgt aaaagtaatt aggcccatta
    15601 tttttaatgc cttttaatgt tttagtaagt tgtggctgct ttacaatatc tccattttta
    15661 acagtattac catctccttt gaaaaaagga gatgatttat caataccttt gctatatttt
    15721 tttatactca tttctaattc agaattaact tcaaaaccgt cttctgctaa aggaataaca
    15781 taatcaaata tttttttact ttgcaacaga acccatattt tttaatcact aataatgcag
    15841 aaaaattaag aatacgctta gaagaattat ttaatgcaaa tacagtttat atacaaagaa
    15901 taaaagatag accattagaa gcgcgtaaag atgttgatga aagagattta gaaaaaattg
    15961 atcaatgtgt tattttattt ggtgatgtga aattaatgat tgcagatgat actgaaggac
    16021 ttccaattac taaaggaaat aatgtttctt tgtgtgtgac attcgaaaat gtcgaagaca
    16081 caaagagaat ttatgataaa ttcgttgaat taggctccga aattttacac ggaaggttac
    16141 ggatatgtta aagatgaatt cggaattgct tatcatctct ttaccaaaag aaaaaattaa
    16201 aaaaagagca tatatcatat gctctttttt taatcataat ttacataatc gatgattatc
    16261 agaagttcta gcataaaaaa gcactacaag ttcatgagct tgtagtgctt tttattgtgt
    16321 taattaccaa acaaccgact ccagaaacct tttttaggtg gtttttcttc cttatcttcg
    16381 tattcattat ctatttcttc gaattgttta tcgtctattg tggatggttc ttcattgagg
    16441 ttttcattct ctttctcttc aggtatatct ttatgctgca cctctgtagg ctgttcccat
    16501 tcttgttgtt gatcagtatc tttagactct ccagtaaatg ttgcttcttg tacattaaca
    16561 ttttgtctct cattaacaga cgtatcaaaa gaataattaa gtcgtctttc ttcctctaat
    16621 tgatcttcta attttttaat ctttttatta ctttctaatg ctaatacttg ttgattctct
    16681 aaaagtctat taagtgtatt tatttgctct ttatctctat ttgattgttc tttatatata
    16741 tctatctggt tatataattg ttttattgtc tcatctttca ccaggttatc attattaggt
    16801 tcttcttttt tttcgctttc aaaatcatca ttcttatttt gattttttct tattcggttt
    16861 attactataa tttcatcttc actggttaag taatttacgt tatcgatttt ttgaaatttc
    16921 acatttgctt ttttagcatt attataaaca gtcatttttg ttacgtttaa ttcatcagca
    16981 atttctttca tactcttcat ataacgccct ccatatagtt atatacataa cgtttatatc
    17041 attatacagc cattatattt gttattacaa ggttatataa ttctttatac acatatccat
    17101 atataactat acgtataagg tttcaaccca attatataac acttatacac cctttatact
    17161 tgctatataa gcgtttatac ggtgttatac gatataccca tataaaataa tttatacaaa
    17221 gatttatctt tctttgaaag tgcatacacc caaatgtata taaacaattt aacaaaactt
    17281 ttaaaagtgt taatataaat atataaaaga aacctaacta cgggaatagt caggtttctt
    17341 cggtaataaa acaagtagtt tgtttgttta tatagttgtt atatttttat tatatatact
    17401 aagaattatt agtgcaagtc gaatacatat aaacttactt atagcttttt tattacctct
    17461 tttagaaatt taaatatgaa agaggttttt tgtatgtcca actttaatat taaagaaatc
    17521 caaaaagaga aattttatca attacctaaa gtttttttta cgaatcctaa atatactaaa
    17581 ctatctaatg atgcaaaaat aacttggtca atactaagag atcgtttaga tttatctata
    17641 agaaataatt gggtagatga aaatggagat atatttttta tttataccaa tgaaaagctt
    17701 aagtctattt taaatattag tagtccaaat aagctatcta aaataaaaaa agaattaaca
    17761 gaagctgatt tatttaatca aattagagta ggtttgaata aacctaataa gttatatatt
    17821 aaaaaaccag aagtaacaga agctgatgta tattatattt cacaacaaga aaacgatata
    17881 gaacagcata ataacacgga cgtatcatta tcatacgtcc agaaatatga taatgatacg
    17941 tcaagaaata ttaatatgat acatcatgac atatcaaaag aatacactaa tgatactgat
    18001 ttaagtaata ctgattatat agagactgag aataatgata cgtatgatat gaatgataca
    18061 tataacaatc aaacaaacca taatcattcg gatcatacaa atcaccaaca atccgaattt
    18121 aataatgatg cacttaaatt ccaagtactc gaagaattgc cacaacaaat caaagattac
    18181 ttaagtaatt ttgaaattaa agaaattcgt attattaaaa
//
