LOCUS       NZ_CP083874            31976 bp    DNA     circular CON 05-NOV-2023
DEFINITION  Escherichia coli strain NDM5 plasmid unnamed2, complete sequence.
ACCESSION   NZ_CP083874
VERSION     NZ_CP083874.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN21398207
            Assembly: GCF_020149625.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 31976)
  AUTHORS   Simner,P., Mostafa,H., Bergman,Y., Ante,M., Tekle,T., Adebayo,A.,
            Beisken,S., Dzintars,K. and Tamma,P.D.
  TITLE     Progressive Development of Cefiderocol Resistance in Escherichia
            coli During Therapy Is Associated with Increased blaNDM-5 Copy
            Number and Gene Expression
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 31976)
  AUTHORS   Simner,P., Mostafa,H., Bergman,Y., Ante,M., Tekle,T., Adebayo,A.,
            Beisken,S., Dzintars,K. and Tamma,P.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-SEP-2021) BioIT, Ares-Genetics, Karl-Farkas-Gasse 18,
            Vienna 1180, Austria
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: JAN-2021
            Assembly Method                   :: Canu v. JAN-2021
            Assembly Name                     :: Isolate5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 285x
            Sequencing Technology :: Oxford Nanopore MiniION + Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/05/2023 01:52:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,938
            CDSs (total)                      :: 4,815
            Genes (coding)                    :: 4,483
            CDSs (with protein)               :: 4,483
            Genes (RNA)                       :: 123
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 13
            Pseudo Genes (total)              :: 332
            CDSs (without protein)            :: 332
            Pseudo Genes (ambiguous residues) :: 0 of 332
            Pseudo Genes (frameshifted)       :: 148 of 332
            Pseudo Genes (incomplete)         :: 195 of 332
            Pseudo Genes (internal stop)      :: 49 of 332
            Pseudo Genes (multiple problems)  :: 61 of 332
            Pseudo Genes (short protein)      :: 4 of 332
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP083874.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..31976
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="NDM5"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="unnamed2"
                     /geo_loc_name="USA: Baltimore"
                     /lat_lon="39.296 N 76.591 W"
                     /collection_date="2020"
                     /collected_by="Johns Hopkins University"
                     /genotype="ST167"
     gene            complement(join(31838..31976,1..>17))
                     /locus_tag="LCE27_RS23000"
                     /old_locus_tag="LCE27_23000"
                     /pseudo=""
     CDS             complement(join(31838..31976,1..>17))
                     /locus_tag="LCE27_RS23000"
                     /old_locus_tag="LCE27_23000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031587700.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /name="IS1380 family transposase"
     gene            24..548
                     /locus_tag="LCE27_RS23005"
                     /old_locus_tag="LCE27_23005"
     CDS             24..548
                     /locus_tag="LCE27_RS23005"
                     /old_locus_tag="LCE27_23005"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_224450642.1"
                     /translation="MTSSPALLPAKMPLDGLYLIPDGNGHWKFTDPRKDRDRVTTINVQ
                     NNGNVLNVIRAVKYWQRRPTMPSMSSYLLETLILDYYAGRTSCSSFVDMELEALFRHLG
                     QSVRYSVNDPKGIQGDINSLSAEARKAISDRCYLDAQKVSEARWFENNKEYEKSINKWR
                     DVFGPFFPVYG"
                     /name="hypothetical protein"
     gene            552..1484
                     /locus_tag="LCE27_RS23010"
                     /old_locus_tag="LCE27_23010"
     CDS             552..1484
                     /locus_tag="LCE27_RS23010"
                     /old_locus_tag="LCE27_23010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001710756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-4TM family putative pore-forming effector"
                     /protein_id="WP_058682609.1"
                     /translation="MNAIYTNQSTRENMDLLYAQARVYDRVKNWNRLNFLFSIIVPLLL
                     SFVTVYNRSREFVDSELLSSLLGLYGLLVLTFNIVISGHISALRRKAASIQEMYDCRVL
                     GIRRNELKVEEIPRDDIIREAAYFRDSPEKARKRFGEEGWYVSKVYDAPQAVMALLCHG
                     KNLGWDKSLREVLHVFYLSAFIVPPVAMLVYGIVMKSGLNEILFYVVFTLPVIRYFLLQ
                     FLDNRSSMKRSEKLKKYVEKELSGIRVSGRAEEEQLAYTLRNIQDEMFTYRASCPPVPN
                     GIQLIMKPKNERIYVDYFETNLKELHLQK"
                     /name="S-4TM family putative pore-forming effector"
     gene            complement(1684..2381)
                     /locus_tag="LCE27_RS23015"
                     /old_locus_tag="LCE27_23015"
     CDS             complement(join(1684..2132,2132..2381))
                     /locus_tag="LCE27_RS23015"
                     /old_locus_tag="LCE27_23015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558260.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1-like element IS1B family transposase"
                     /protein_id="WP_224434100.1"
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTIFRHFKKLRPQSVTSRIQPGSDVIV
                     CAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVFAHVFGERTMATLGRLMSLLSPFDVVIW
                     MTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVI
                     GHYLNIKHYQ"
                     /name="IS1-like element IS1B family transposase"
     gene            complement(2510..3207)
                     /locus_tag="LCE27_RS23020"
                     /old_locus_tag="LCE27_23020"
     CDS             complement(join(2510..2958,2958..3207))
                     /locus_tag="LCE27_RS23020"
                     /old_locus_tag="LCE27_23020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558260.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1-like element IS1B family transposase"
                     /protein_id="WP_224434100.1"
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTIFRHFKKLRPQSVTSRIQPGSDVIV
                     CAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVFAHVFGERTMATLGRLMSLLSPFDVVIW
                     MTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVI
                     GHYLNIKHYQ"
                     /name="IS1-like element IS1B family transposase"
     gene            3355..3513
                     /locus_tag="LCE27_RS23025"
                     /old_locus_tag="LCE27_23025"
     CDS             3355..3513
                     /locus_tag="LCE27_RS23025"
                     /old_locus_tag="LCE27_23025"
                     /inference="COORDINATES: protein motif:HMM:NF025713.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="WP_228955855.1"
                     /translation="MLRSSAAILHGINNLRNNYSMAHPTETLLNEADARFAINLVRSIM
                     TYVDELL"
                     /name="abortive infection family protein"
     gene            complement(3671..>4643)
                     /locus_tag="LCE27_RS23030"
                     /old_locus_tag="LCE27_23030"
                     /pseudo=""
     CDS             complement(3671..>4643)
                     /locus_tag="LCE27_RS23030"
                     /old_locus_tag="LCE27_23030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001420487.1"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            5400..6377
                     /locus_tag="LCE27_RS23035"
                     /old_locus_tag="LCE27_23035"
     CDS             5400..6377
                     /locus_tag="LCE27_RS23035"
                     /old_locus_tag="LCE27_23035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052630.2"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="WP_000361611.1"
                     /translation="MDKSSGELVTLTPNNNNTVQPVALMRLGVFVPTLKSLKNSKKNTL
                     SRTDATEELTRLSLARAEGFDKVEITGPRLDMDNDFKTWVGIIHSFARHNVIGDKVELP
                     FVEFAKLCGIPSSQSSRRLRERISPSLKRIAGTVISFSRTDEKHTREYITHLVQSAYYD
                     TERDIVQLQADPRLFELYQFDRKVLLQLKAINALKRRESAQALYTFIESLPRDPAPISL
                     ARLRARLNLKSPVFSQNQTVRRAMEQLREIGYLDYTEIQRGRTKFFCIHYRRPRLKAPN
                     DESKENPLQPSPAEKVSPEMAEKLALLEKLGITLDDLEKLFKSR"
                     /name="RepB family plasmid replication initiator protein"
     gene            complement(6662..7402)
                     /locus_tag="LCE27_RS23040"
                     /old_locus_tag="LCE27_23040"
     CDS             complement(6662..7402)
                     /locus_tag="LCE27_RS23040"
                     /old_locus_tag="LCE27_23040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052628.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA];
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_001066953.1"
                     /translation="MNNVIPLQNSPERVSLLPIAPGVDFATALSLRRMATSTGATPAYL
                     LAPEVSALLFYMPDQRHHMLFATLWNTGMRIGEARMLTPESFDLNGVRPFVRILSEKVR
                     ARRGRPPKDEVRLVPLTDISYVRQMESWMITTRPRRREPLWAVTDETMRNWLKQAVRRA
                     EADGVHFSIPVTPHTFRHSYIMHMLYHRQPRKVIQALAGHRDPRSMEVYTRVFALDMAA
                     TLAVPFTGDGRDAAEILRTLPPLR"
                     /name="tyrosine-type recombinase/integrase"
     gene            complement(7523..7705)
                     /locus_tag="LCE27_RS23045"
                     /old_locus_tag="LCE27_23045"
     CDS             complement(7523..7705)
                     /locus_tag="LCE27_RS23045"
                     /old_locus_tag="LCE27_23045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_042344623.1"
                     /translation="MHVAQLPSLCIFLLSLRSSLPWHYPISPKNGKPALSPRHDWLNTG
                     SLLQNIPLRIWFYPQ"
                     /name="hypothetical protein"
     gene            complement(7772..8061)
                     /locus_tag="LCE27_RS23050"
                     /old_locus_tag="LCE27_23050"
                     /pseudo=""
     CDS             complement(7772..8061)
                     /locus_tag="LCE27_RS23050"
                     /old_locus_tag="LCE27_23050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220181.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(8083..8314)
                     /locus_tag="LCE27_RS23055"
                     /old_locus_tag="LCE27_23055"
                     /pseudo=""
     CDS             complement(8083..8314)
                     /locus_tag="LCE27_RS23055"
                     /old_locus_tag="LCE27_23055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017441118.1"
                     /GO_process="GO:0051983 - regulation of chromosome
                     segregation [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system ParD family
                     antitoxin"
                     /name="type II toxin-antitoxin system ParD family
                     antitoxin"
     gene            8846..10015
                     /locus_tag="LCE27_RS23060"
                     /old_locus_tag="LCE27_23060"
     CDS             8846..10015
                     /locus_tag="LCE27_RS23060"
                     /old_locus_tag="LCE27_23060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001072355.1"
                     /translation="MNQKWKTLIISLLTPSSIISGIALIVLWGYFSRLGRLDIFFDVMN
                     IKSILVLVCCATILSLAMIVFIFFITSFFIPVVIPQDINNLPAYNKIQGNFLSVMMLSG
                     MFPMAFIYVLYCAFDFDQNVKDNSGWLSIASMGVLIAVILAIVNKRYLEYDLSFKNNRM
                     KLLRRVQIYLVIPLSIALLVHLQLIPLEIVFSNIATSDKSVNFKVIAELAFMSYFIFLL
                     TMLPGVIYLKMNPQHKFSKRISYSFIASLMLLLIISTQITVLPVIFTHSVIKLSGISDF
                     KIHSYIIKTSEYPEEFFSNAAWDKKNIKPGDYYSVQAVSMFTTNQFILLCPKDIIKFYR
                     ESWKFELLNVDFDINTRKKLQEEAAYCVPISAISVKRWDMPLQGSKPSS"
                     /name="hypothetical protein"
     gene            <10048..10176
                     /locus_tag="LCE27_RS23065"
                     /old_locus_tag="LCE27_23065"
                     /pseudo=""
     CDS             <10048..10176
                     /locus_tag="LCE27_RS23065"
                     /old_locus_tag="LCE27_23065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014543172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS481 family transposase"
                     /name="IS481 family transposase"
     gene            complement(<10301..10504)
                     /locus_tag="LCE27_RS23070"
                     /old_locus_tag="LCE27_23070"
                     /pseudo=""
     CDS             complement(<10301..10504)
                     /locus_tag="LCE27_RS23070"
                     /old_locus_tag="LCE27_23070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052678.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            10574..11273
                     /locus_tag="LCE27_RS23075"
                     /old_locus_tag="LCE27_23075"
                     /pseudo=""
     CDS             10574..11273
                     /locus_tag="LCE27_RS23075"
                     /old_locus_tag="LCE27_23075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            complement(11389..11665)
                     /locus_tag="LCE27_RS23080"
                     /old_locus_tag="LCE27_23080"
                     /pseudo=""
     CDS             complement(11389..11665)
                     /locus_tag="LCE27_RS23080"
                     /old_locus_tag="LCE27_23080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052677.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]; GO:0009432 - SOS response [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(11665..11949)
                     /locus_tag="LCE27_RS23085"
                     /old_locus_tag="LCE27_23085"
     CDS             complement(11665..11949)
                     /locus_tag="LCE27_RS23085"
                     /old_locus_tag="LCE27_23085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="WP_001387467.1"
                     /translation="MQMKNNAAQATKVITAHVPLPMADKVDQMAARLERSRGWVIKQAL
                     SAWLAQEEERNRLTLEALDDVTSGQVIDHQAVQAWSDSLSTDNPLPVPR"
                     /name="ribbon-helix-helix domain-containing protein"
     gene            12504..13208
                     /locus_tag="LCE27_RS23090"
                     /old_locus_tag="LCE27_23090"
     CDS             12504..13208
                     /locus_tag="LCE27_RS23090"
                     /old_locus_tag="LCE27_23090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(<13263..14129)
                     /gene="intI1"
                     /locus_tag="LCE27_RS23095"
                     /old_locus_tag="LCE27_23095"
                     /pseudo=""
     CDS             complement(<13263..14129)
                     /gene="intI1"
                     /locus_tag="LCE27_RS23095"
                     /old_locus_tag="LCE27_23095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221021.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 integron integrase IntI1"
                     /name="intI1"
     gene            14274..14771
                     /gene="dfrA12"
                     /locus_tag="LCE27_RS23100"
                     /old_locus_tag="LCE27_23100"
     ARG             14275..14768
                     /name="dfrA12"
                     /gene="dfrA12"
                     /gene_name="trimethoprim-resistant dihydrofolate reductase
                     DfrA12"
                     /tool="amrfinderplus"
                     /drug_class="TRIMETHOPRIM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            14924..15172
                     /locus_tag="LCE27_RS23105"
                     /old_locus_tag="LCE27_23105"
     CDS             14924..15172
                     /locus_tag="LCE27_RS23105"
                     /old_locus_tag="LCE27_23105"
                     /inference="COORDINATES: protein motif:HMM:NF017990.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1010 domain-containing protein"
                     /protein_id="WP_224450643.1"
                     /translation="MPVLPFSGLRLHGLRRFSVFLASSPCVASASSYRFCSAVPPRWRS
                     VFSRLAPVAKFKLSVLASGSNISVKPTRILRSAYLAR"
                     /name="DUF1010 domain-containing protein"
     gene            15178..16016
                     /locus_tag="LCE27_RS23110"
                     /old_locus_tag="LCE27_23110"
                     /pseudo=""
     CDS             15178..16016
                     /locus_tag="LCE27_RS23110"
                     /old_locus_tag="LCE27_23110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749984.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="AadA family aminoglycoside
                     3''-O-nucleotidyltransferase"
                     /name="AadA family aminoglycoside
                     3''-O-nucleotidyltransferase"
     gene            16133..16480
                     /locus_tag="LCE27_RS23115"
                     /old_locus_tag="LCE27_23115"
     CDS             16133..16480
                     /locus_tag="LCE27_RS23115"
                     /old_locus_tag="LCE27_23115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /protein_id="WP_000679427.1"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAFY
                     FLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLARSP
                     SWKSLRRPTPW"
                     /name="quaternary ammonium compound efflux SMR transporter
                     QacE delta 1"
     gene            16474..17313
                     /gene="sul1"
                     /locus_tag="LCE27_RS23120"
                     /old_locus_tag="LCE27_23120"
     ARG             16475..17310
                     /name="sul1"
                     /gene="sul1"
                     /gene_name="sulfonamide-resistant dihydropteroate synthase
                     Sul1"
                     /tool="amrfinderplus"
                     /drug_class="SULFONAMIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            17718..19259
                     /locus_tag="LCE27_RS23125"
                     /old_locus_tag="LCE27_23125"
     CDS             17718..19259
                     /locus_tag="LCE27_RS23125"
                     /old_locus_tag="LCE27_23125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000050481.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91-like element ISCR1 family transposase"
                     /protein_id="WP_000050481.1"
                     /translation="MSLARNATASQSPTQTNGYERHQPDQTLLYQLVEQHYPAFKASLE
                     AQGQHLPRYIQQEFNDLLQCGRLEYGFMRVRCEDCHHERLVAFSCKRRGFCPSCGARRM
                     AESAALLIDEVFPKEPIRQWVLSFPFQLRFLLARHPQLMGQVLSIVYRTLSTHLIKKAG
                     YTKASAQTGSVTLIQRFGSALNLNVHYHMLFLDGVYAEDDYGKQRFHRVKAPTYDELNT
                     LAHTLSHRIARCMEKRGILERDAENTWLTLEEGEDDTLTQLHGASVTYRIAVGPQQGRK
                     VFTLQTLPGREDKADSSSRVANHAGFSLHAGVMAEAHQRDKLERLCRYISRPAVSEKRL
                     ALTANGQVRYELKTPYRNGTTHVIFEPLDFIAKLAALVPKPRVNLTRFHGVFAPNSKHR
                     VQVTPAKRGKKPDKSEGLDTNWRDKSPAERHRAMTWMQRLKRVFNIDIEVCEHCGGHVK
                     VIASIEDPKVIEQILKHLKQKTAKANAAKQRELPPERAPPLTPSLFDPSQSRLFD"
                     /name="IS91-like element ISCR1 family transposase"
     gene            19572..>19946
                     /locus_tag="LCE27_RS23130"
                     /old_locus_tag="LCE27_23130"
                     /pseudo=""
     CDS             19572..>19946
                     /locus_tag="LCE27_RS23130"
                     /old_locus_tag="LCE27_23130"
                     /inference="COORDINATES: protein motif:HMM:NF022853.3"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD family protein"
                     /name="protein-disulfide reductase DsbD family protein"
     gene            <20046..20603
                     /locus_tag="LCE27_RS23135"
                     /old_locus_tag="LCE27_23135"
                     /pseudo=""
     CDS             <20046..20603
                     /locus_tag="LCE27_RS23135"
                     /old_locus_tag="LCE27_23135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006399920.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocation (TAT) pathway signal
                     sequence domain protein"
                     /name="twin-arginine translocation (TAT) pathway signal
                     sequence domain protein"
     gene            complement(20614..21252)
                     /locus_tag="LCE27_RS23140"
                     /old_locus_tag="LCE27_23140"
     CDS             complement(20614..21252)
                     /locus_tag="LCE27_RS23140"
                     /old_locus_tag="LCE27_23140"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201168.1"
                     /GO_function="GO:0004640 - phosphoribosylanthranilate
                     isomerase activity [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="WP_004201168.1"
                     /translation="MPAKIKICGISTPEALDATIAARADYAGLVFYPASPRAVTSNVAG
                     ALTSRAAGQIAMVGLFVDADDAVIADALVAAKLNALQLHGSESPERVAQLRARFGKPVW
                     KALPVASASDVARAAAYAGAADLILFDAKTPKGALPGGMGLAFDWSLLAGYRGALPWGL
                     AGGLNPTNVAEAIARTGAPLVDTSSGVESAPGVKDTDKITNFAFAVRLA"
                     /name="phosphoribosylanthranilate isomerase"
     gene            complement(21257..21621)
                     /gene="ble"
                     /locus_tag="LCE27_RS23145"
                     /old_locus_tag="LCE27_23145"
                     /pseudo=""
     CDS             complement(21257..21621)
                     /gene="ble"
                     /locus_tag="LCE27_RS23145"
                     /old_locus_tag="LCE27_23145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201167.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="bleomycin binding protein Ble-MBL"
                     /name="ble"
     gene            complement(21625..22437)
                     /locus_tag="LCE27_RS23150"
                     /old_locus_tag="LCE27_23150"
     CDS             complement(21625..22437)
                     /locus_tag="LCE27_RS23150"
                     /old_locus_tag="LCE27_23150"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032492661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="subclass B1 metallo-beta-lactamase NDM-5"
                     /protein_id="WP_023408309.1"
                     /translation="MELPNIMHPVAKLSTALAAALMLSGCMPGEIRPTIGQQMETGDQR
                     FGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLLVDTAWTDDQTAQILNW
                     IKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGLVAAQHSLTF
                     AANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLG
                     DADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR"
                     /name="subclass B1 metallo-beta-lactamase NDM-5"
     gene            complement(22538..>22831)
                     /locus_tag="LCE27_RS23155"
                     /old_locus_tag="LCE27_23155"
                     /pseudo=""
     CDS             complement(22538..>22831)
                     /locus_tag="LCE27_RS23155"
                     /old_locus_tag="LCE27_23155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611607.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /name="IS30 family transposase"
     gene            22996..23700
                     /locus_tag="LCE27_RS23160"
                     /old_locus_tag="LCE27_23160"
     CDS             22996..23700
                     /locus_tag="LCE27_RS23160"
                     /old_locus_tag="LCE27_23160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            23822..24736
                     /locus_tag="LCE27_RS23165"
                     /old_locus_tag="LCE27_23165"
     CDS             23822..24736
                     /locus_tag="LCE27_RS23165"
                     /old_locus_tag="LCE27_23165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(A) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_023063803.1"
                     /translation="MTVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVDD
                     GRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTAMV
                     IQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVADDV
                     DRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMIDWSE
                     ARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVTYALFA
                     LDSGNEEYLAAAKAQLAAAEAAE"
                     /name="Mph(A) family macrolide 2'-phosphotransferase"
     gene            24733..25969
                     /gene="mrx(A)"
                     /locus_tag="LCE27_RS23170"
                     /old_locus_tag="LCE27_23170"
                     /gene_synonym="mrx"
                     /pseudo=""
     CDS             24733..25969
                     /gene="mrx(A)"
                     /locus_tag="LCE27_RS23170"
                     /old_locus_tag="LCE27_23170"
                     /gene_synonym="mrx"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004159.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide resistance MFS transporter Mrx(A)"
                     /name="mrx(A)"
     gene            25959..26552
                     /gene="mphR(A)"
                     /locus_tag="LCE27_RS23175"
                     /old_locus_tag="LCE27_23175"
     CDS             25959..26552
                     /gene="mphR(A)"
                     /locus_tag="LCE27_RS23175"
                     /old_locus_tag="LCE27_23175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide-binding transcriptional repressor
                     MphR(A)"
                     /protein_id="WP_106490008.1"
                     /translation="MNTDARPKLKSDDEVLEAATVVLKRCGPIEFTLSGVAKEVGLSRA
                     ALIQRFTNRDTLLVRMMERGVEQVRHYLNAIPIGAGPQGLWEFLQVLVRSMNTRNDFSV
                     NYLISWYELQVPELRTLAIQRNRAVVEGIRKRLPPGAPAAAELLLHSVIAGATMQWAVD
                     PDGELADHVLAQIAAILCLMFPEHDDFQLLQAHA"
                     /name="mphR(A)"
     gene            complement(27045..>27509)
                     /locus_tag="LCE27_RS23180"
                     /old_locus_tag="LCE27_23180"
                     /pseudo=""
     CDS             complement(27045..>27509)
                     /locus_tag="LCE27_RS23180"
                     /old_locus_tag="LCE27_23180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389365.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS6100 family transposase"
                     /name="IS6-like element IS6100 family transposase"
     gene            complement(27561..28265)
                     /locus_tag="LCE27_RS23185"
                     /old_locus_tag="LCE27_23185"
     CDS             complement(27561..28265)
                     /locus_tag="LCE27_RS23185"
                     /old_locus_tag="LCE27_23185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(<28342..>30560)
                     /locus_tag="LCE27_RS23190"
                     /old_locus_tag="LCE27_23190"
                     /pseudo=""
     CDS             complement(<28342..>30560)
                     /locus_tag="LCE27_RS23190"
                     /old_locus_tag="LCE27_23190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611787.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /name="Tn3-like element Tn3 family transposase"
     gene            <30574..30918
                     /locus_tag="LCE27_RS23195"
                     /old_locus_tag="LCE27_23195"
                     /pseudo=""
     CDS             <30574..30918
                     /locus_tag="LCE27_RS23195"
                     /old_locus_tag="LCE27_23195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016943399.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="WbuC family cupin fold metalloprotein"
                     /name="WbuC family cupin fold metalloprotein"
     gene            complement(30965..>31738)
                     /gene="bla"
                     /locus_tag="LCE27_RS23200"
                     /old_locus_tag="LCE27_23200"
                     /pseudo=""
     CDS             complement(30965..>31738)
                     /gene="bla"
                     /locus_tag="LCE27_RS23200"
                     /old_locus_tag="LCE27_23200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011091028.1"
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]; GO:0046677 - response to antibiotic
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase"
                     /name="bla"
     ARG             16134..16477
                     /name="qacEdelta1"
                     /gene="qacEdelta1"
                     /gene_name="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             23823..24724
                     /name="mph(A)"
                     /gene="mph(A)"
                     /gene_name="Mph(A) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(21629..22437)
                     /name="blaNDM-5"
                     /gene="blaNDM-5"
                     /gene_name="subclass B1 metallo-beta-lactamase NDM-5"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             15179..15966
                     /name="aadA2"
                     /gene="aadA2"
                     /gene_name="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA2"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             23823..24736
                     /name="mphA"
                     /gene="mphA"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="100.0"
                     /coverage="101.0"
     ARG             15191..15969
                     /name="aadA2"
                     /gene="aadA2"
                     /gene_name="ANT(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(30966..31693)
                     /name="CTX-M-163"
                     /gene="CTX-M-163"
                     /gene_name="CTX-M beta-lactamase"
                     /tool="rgi"
                     /drug_class="cephalosporin"
                     /identity="99.59"
                     /coverage="83.16"
     ARG             24734..25962
                     /name="Mrx"
                     /gene="Mrx"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="100.0"
                     /coverage="99.27"
     Typing          5401..6377
                     /name="IncFIB"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.875"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ctggtcagca aggactggga attttgacat cgtcccctgc tttattacca gcgaagatgc
       61 ctttggacgg actttacctg atccccgatg gcaacggcca ctggaagttt accgaccccc
      121 gtaaagacag ggacagagtc actactatca atgtgcagaa taacggcaat gtgctcaatg
      181 tcatcagagc agtcaaatac tggcagcggc gaccgacgat gccatccatg agttcctacc
      241 tgctggaaac gctgattctg gactattacg ccggcaggac atcctgctca tcgtttgttg
      301 acatggagct ggaagcgctt ttccgccacc ttggtcaatc cgtgcggtac tctgtcaacg
      361 atcccaaagg catacagggt gatatcaact cactttcagc cgaggcacgt aaggcgatat
      421 cggacagatg ttatctcgat gcgcaaaagg tatcggaggc gagatggttt gaaaataata
      481 aagagtatga aaaatccatc aataaatggc gcgatgtgtt cgggccattc tttcctgttt
      541 acgggtgaat catgaatgcc atttacacaa accagtcgac cagagaaaac atggatttac
      601 tgtatgcgca ggcccgtgtc tacgacaggg taaaaaactg gaacagactg aattttctct
      661 tcagcatcat cgtaccgctc ctgctttctt tcgttaccgt atacaaccgg agccgggaat
      721 ttgtcgattc agagttgttg tcttcgctgt tggggttata tggactcctg gtgcttacct
      781 ttaacattgt tatcagtgga cacatctcgg ctctgcgcag gaaggcagcc tcaatccagg
      841 aaatgtacga ctgccgggta cttggcatcc ggcgtaatga actgaaggtg gaggagatcc
      901 cacgggatga catcatccgg gaagctgcat attttagaga cagcccggaa aaagcacgaa
      961 agcgatttgg cgaagagggg tggtacgtca gtaaggtgta tgacgcgccg caggccgtaa
     1021 tggcgctcct ttgccacgga aaaaatctcg gctgggacaa atcgctcagg gaggttctgc
     1081 acgtatttta tctttccgct tttattgtcc cgcctgtcgc gatgcttgtt tacggcatcg
     1141 tcatgaaatc cgggctgaat gagatcctct tctatgtggt gttcacactg ccggtcatcc
     1201 gctatttctt gcttcagttt ctggataatc gcagcagtat gaaaagaagc gagaagctga
     1261 aaaagtacgt tgagaaggaa ttatccggca taagggtgtc cggaagggca gaagaagagc
     1321 aactggctta tacgctccgg aatatccaag atgagatgtt tacctaccgg gcctcatgtc
     1381 cgcccgtacc caacggtatt cagctgataa tgaagcccaa aaatgaacga atttatgttg
     1441 attactttga aacaaatctg aaggagctgc accttcagaa gtaatccctc cttagctccg
     1501 gtgtaggatt tacgtatgcc ggagcacatc cgataaacaa ttcttggttg cctgagtgtc
     1561 agcgtaaacc catagtcacc ttcgcctcag acggttagta acacagtatt gcaaacaaca
     1621 tttcagctcc tttgaaatta aaaggacaac tcttgatgct ctcatgacgg taatgactcc
     1681 aacttactga tagtgtttta tgttcagata atgcccgatg actttgtcat gcagctccac
     1741 cgattttgag aacgacagcg acttccgtcc cagccgtgcc aggtgctgcc tcagattcag
     1801 gttatgccgc tcaattcgct gcgtatatcg cttgctgatt acgtgcagct ttcccttcag
     1861 gcgggattca tacagcggcc agccatccgt catccatatc accacgtcaa agggtgacag
     1921 caggctcata agacgcccca gcgtcgccat agtgcgttca ccgaatacgt gcgcaaaaac
     1981 cgtcttccgg agcctgtcat acgcgtaaaa cagccagcgc tggcgcgatt tagccccgac
     2041 gtatccccac tgttcgtcca tttccgcgca gacgatgacg tcactgcccg gctgtatgcg
     2101 cgaggttacc gactgcggcc tgagtttttt aaatggcgga aaatcgtgtt gaggccaacg
     2161 cccataatgc gggcggttgc ccggcatcca acgccattca tggccatatc aatgattttc
     2221 tggtgcgtac cgggttgaga agcggtgtaa gtgaactgca gttgccatgt tttacggcag
     2281 tgagagcaga gatagcgctg atgtccggca gtgcttttgc cgttacgcac caccccgtca
     2341 gtagctgaac aggagggaca gctgatagaa acagaagcca caggagcacc tcaaaaacac
     2401 catcatacac taaatcagta agttggcagc atcaccctga aactactgtc atgaagccgc
     2461 gtttagcttc acctgtagca gcatcagtaa agccggtaat gactccaact tactgatagt
     2521 gttttatgtt cagataatgc ccgatgactt tgtcatgcag ctccaccgat tttgagaacg
     2581 acagcgactt ccgtcccagc cgtgccaggt gctgcctcag attcaggtta tgccgctcaa
     2641 ttcgctgagt gtaacgcttg ctgattacgt gcagctttcc cttcaggcgg gattcataca
     2701 gcggccagcc atccgtcatc catatcacca cgtcaaaggg tgacagcagg ctcataagac
     2761 gccccagcgt cgccatagtg cgttcaccga atacgtgcgc aaaaaccgtc ttccggagcc
     2821 tgtcatacgc gtaaaacagc cagcgctggc gcgatttagc cccgacgtat ccccactgtt
     2881 cgtccatttc cgcgcagacg atgacgtcac tgcccggctg tatgcgcgag gttaccgact
     2941 gcggcctgag ttttttaaat ggcggaaaat cgtgttgagg ccaacgccca taatgcgggc
     3001 ggttgcccgg catccaacgc cattcatggc catatcaatg attttctggt gcgtaccggg
     3061 ttgagaagcg gtgtaagtga actgcagttg ccatgtttta cggcagtgag agcagagata
     3121 gcgctgatgt ccggcagtgc ttttgccgtt acgcaccacc ccgtcagtag ctgaacagga
     3181 gggacagctg atagaaacag aagccacagg agcacctcaa aaacaccatc atacactaaa
     3241 tcagtaagtt ggcagcatca ccgtacaaat gataatgttc caggcttgct ttccctgata
     3301 actgcacatc tcaaagacct gcctgatgat ggaagaaatg aagatgtgtt taaaatgttg
     3361 agatcatctg ccgcaatact tcatgggatc aataacctgc gtaacaatta cagcatggcc
     3421 catcctactg aaactttgct gaatgaagcc gatgcccgtt ttgccataaa tctggttcgt
     3481 tccatcatga cttatgttga tgagttgctt tagttttaat aaaaatatga gactcacagc
     3541 gaacagatag aacttcaacg aagaagtgaa gtacggccag aatttcgagc tctggccctc
     3601 cggaagatgc cggacagacg catcatcccg tcgcggccgc ttccattttt tgtgtactca
     3661 acctgccgga tcaggatggc ggcaggattt gcacccgatg ttccagccgc cttgcctctt
     3721 cctgatcccg gtattccctc gcctttttca tcatttctgc cgttggctcc tgcagtttgt
     3781 cgagaaactc cttagatcgt ttagccaccg actgaaggga gacactgtcc gtcctgccgg
     3841 tattgcgatt ggtgtaaacc aggcgggtaa gggggtctgg ttaactcctt cccttccata
     3901 aagcgtttga agatccagag atatatatca accagctcca gccctgcact ttttgtaccc
     3961 gactggaaaa ccagcggttc agccggcatg ttcgtcacat ccatgaccgg taaaccggga
     4021 ccgtgtaccc acggcatctc acgtatctgg taatagaact ccctcagctc ccgctgggtg
     4081 gtgttgaact gtgactgctg gtccacaacg atgtcggctt tgcgatttgg tgctcccagg
     4141 cgggaacaga taccgcgcaa tacgaactga aatccaacca tattgggcat gatctgcagc
     4201 ttttgtttac cggttttgca gttatatccc agttcgtcaa agtgggtcat cgcccaggac
     4261 aacgcatcgg taatcaattc aatgtaacgg cggtccccca gggtatgaac gcgcgcaagc
     4321 agctcactgc agacctcact gaacagagat gaggaccttc catcatgggc ttcgaggcgg
     4381 gcacgccacg ctttttcagc cagttcatta tcgaacaggc ttgccagatt cagtagcagc
     4441 gggtaacgaa agggggtcca gtaggcaacc ctgggcactg caggattcat cccctgatcg
     4501 aagaacgaaa taatggcgtg atcccgttta acgaccagcc agacatcaaa ccgtatccgg
     4561 tgcttcttct gcaggacaag caacgtatca accacctcat caaggcggtg catgccaagc
     4621 tctgcggcgt gcagacgctg tacttgtcaa cgccacgatc tttgaccgtc ttatatcgac
     4681 agagttatcc ggcatggtgt caatccgttc acaatttttc catcggagca gcctaccacc
     4741 ggtgataacc agactttgcc tgtagtttgt atacacaatc cctggcattg aaacacacat
     4801 atgaagtgta cttcggatat gaccgtacgc tcaggaagta cggcagattc cgtcaaaaat
     4861 tacctgtaaa gacagacatc agaaaaaacg gtgctcgccg cagaccggtg accgggcgaa
     4921 gcccgcgaac cggcgaggaa gcgcaatgga tctgtaatca cagtgagcag gtacgccctg
     4981 aagccttcat aatcggtagt gtatgctgtt tttccggaat gatttatcca catatccgga
     5041 ggcccgatcc agtaaacaga tccatgaatg atcaacaaag gatccattaa agatccccat
     5101 accgctgcaa accttgtcac tcatgggccg ggaccacgat cacataagct gtggcatgtt
     5161 actgataaac tgtaacatgc taatgataag ctgtattcag taatccatat actgaagtaa
     5221 gttaatgaca taaactatgg tcagtatgcc agactcagtt gttaaataca ggctgcaggt
     5281 ttttcttcag tcagttagcg gagttctgac acacgatttt ctgtttattc ttttactgtc
     5341 cacaggctgg aggctttctg gaaaacgaaa attcagacat caaaaaactg ttcggcgagg
     5401 tggataagtc ctccggtgag ctggtgacac tgacaccaaa caataacaac accgtacaac
     5461 ctgtggcgct gatgcgtctg ggcgtttttg taccgaccct taaatcactg aagaacagta
     5521 aaaaaaatac actgtcacgt actgatgcca cggaagagct gacacgtctt tccctggccc
     5581 gtgctgaggg attcgataag gttgagatca ccggcccccg cctggatatg gataatgatt
     5641 tcaagacctg ggtggggatc attcattcct ttgcccgcca taacgtgatt ggtgacaaag
     5701 ttgaactgcc ttttgttgag tttgcaaaac tgtgtggtat accttcaagc cagtcatccc
     5761 gcaggctgcg tgagcgcatc agcccttccc tgaagcgcat tgccggtacc gtgatttcgt
     5821 tttcccgtac cgatgagaag cacacccggg aatacatcac ccatctggta cagtcagcct
     5881 actacgatac tgagcgggat attgttcagt tacaggccga tccccgcctg tttgaactgt
     5941 accagtttga cagaaaagtc cttctccagc ttaaggcgat taatgccctg aagcgacggg
     6001 agtccgccca ggcactctac acctttatag agagcctgcc ccgggatccg gcaccgatat
     6061 cgctggcgcg gctgcgtgca cgcctcaatc tgaagtctcc tgtattttcc cagaaccaga
     6121 cggtcagacg ggcaatggag cagttgcgcg agattggata tcttgattac acggagatcc
     6181 agcgggggcg gacaaaattc ttctgtattc actaccggcg tccccggtta aaagcgccga
     6241 atgacgagag taaggaaaat ccgttgcaac cttcacctgc ggaaaaagtc agtccggaga
     6301 tggcggagaa gcttgccctg cttgagaaac tgggcatcac gctggatgac ctggaaaaac
     6361 tcttcaaatc ccgctgaaca taaactgtag tcagtgaaga gcgctccttt actgactaca
     6421 gcttatatta tcaggtacag tgagtggtct gctcactgca gtttatattc agtttcctgc
     6481 agtgctgtct gtagctgagc tgccatccgc ctgtccctta cgtaagtgag cccgtaacct
     6541 gatgctgagg cattgctccc ttcataaaac atgacttact cactacagct tatatacatg
     6601 ctccagctta tgttatgtct gttctgctga ccacagctta tataaggaag cgcgtatgcc
     6661 gtcacctcag gggaggcagt gtacgcagga tctccgcagc atcccgcccg tcacctgtga
     6721 aaggcactgc cagcgtggca gccatatcca gtgcaaacac tctggtataa acctccatcg
     6781 aacgtggatc cctgtgacca gccagtgcct gaatgacttt ccggggctgg cggtgataga
     6841 gcatgtgcat gatatagctg tgccggaagg tgtgtggtgt gaccggaatc gaaaagtgta
     6901 ccccgtcagc ttcggcccgt ctgacagcct gcttcagcca gttgcgcatg gtttcgtcgg
     6961 tcacggccca taatggttca cgacgacggg gccgggtggt gatcatccag ctttccatct
     7021 gcctgacata gcttatatct gtcagcggca ccagtcgcac ttcatctttt ggcgggcgtc
     7081 cgcgtcgcgc acgcactttt tcggacagga tccgcacaaa cggtcttact ccattcaggt
     7141 caaatgattc cggcgtcagc atccgggctt cgccaatacg cattccggta ttccagaggg
     7201 tggcgaacag catatggtga cgctgatccg gcatatagaa gagaagggca ctcacttccg
     7261 gggccagcag gtaggccggt gtggcccccg tggaagtggc cattcttctc agggagagcg
     7321 ctgttgcaaa atccaccccc ggcgcaatgg gtaacaggga gacgcgttct ggtgaattct
     7381 gcaggggaat gacattgttc atgagttatt tttcacgtag cacacgcact gtttatggat
     7441 acaggtattc tgacctgaac gcccggatcc ttccacgaca ataaatcgca gcgcgcggat
     7501 ccttttgttt gcttatcacg cattattgcg ggtaaaacca aatacgtaaa ggtatgtttt
     7561 gcagcaggga tcccgtatta agccagtcgt ggcgcgggct gagggctggt ttgccgtttt
     7621 tgggagaaat ggggtaatgc cagggcaaag atgatcgcaa ggaaaggaga aaaatacaca
     7681 gagaggggag ttgcgctacg tgaattctgg ctaggtacac ccctgtaacc ctgccagttt
     7741 tcacgcaacg caatgtggtg gctgattact gtcagttgaa atgacggctg gcatcctgat
     7801 gctgacttaa tatacgaata ataacaattt cagtatcagt ctgcagaaaa taaaccatat
     7861 gccgttcaac gggtagtgcg aatgtgtatt ccccagttca ggagggggag taccgatatt
     7921 atgattactc ataacctgaa aaatgtcgga tatctgatta atatatttat cagcctactc
     7981 ttcaccgaaa tggtggtacc cgtaatgcta gatatcctcc agatcctgac tggctttagg
     8041 tgtgagttta acggttttca ccggaagccc tcgcgccagc tttcactttt tcagaaacgc
     8101 attttttccc acgacacagg ttcaccgctg ctcaagcctt ctgccagtaa atcccgcagg
     8161 acacctggag acgtgactct gcctgtttct ctcgaaggag acgaagtgac tcgcggatta
     8221 cctcactctg tgtacgataa tcacctgatt ctatgagaga ttctatgtac tcccagagtt
     8281 catctccgag agcaactgtc attgttctgg ccatatcaag cctcgtgatt gtaagtttaa
     8341 attttacatg cagtttattc gatactcaaa ggtgcttcca gtacagaaca tttgggagaa
     8401 ttggggtaat gcctggaaca gacagatacg gagaaaaacc ctgcagataa ccttatacga
     8461 caactgaagg tgtctgatgc catattctta gctacttctc tgtcttcagg cggcttagtc
     8521 acaacataag accgatgcat aataagcata ttttttcatg ttatggtctt gttcatgcat
     8581 gaactattat ctattcagtc acttttaaag ttttatatca tactgcatat gatatatatc
     8641 atctcctata ttcagactaa aaatattatg acgatggtca aatgaattta gtgaaaacgc
     8701 tacctaaaac aatatgctta tgatataact tatcaagaat atgcgacaat cttcttgaaa
     8761 ggttacggag aagagtcaga taatgaagtg ttataactca ttcagctttt ttatgttctc
     8821 tttatagtaa aaccaggaga ttaagatgaa tcagaagtgg aagacgttaa ttatttcatt
     8881 attaacacca tcaagtatta tatcagggat tgcgttgata gttctctggg gatatttcag
     8941 tcgcctgggc cgactagata ttttctttga tgtaatgaat attaaaagca tcttggtatt
     9001 ggtttgttgt gcaactatac tatcattggc tatgatagta tttatctttt ttataacctc
     9061 tttttttata cccgtagtta ttcctcagga tataaataat cttcctgctt acaataagat
     9121 tcagggtaat tttttatctg tgatgatgtt atctggcatg ttccccatgg cctttatata
     9181 tgtgttatac tgtgcatttg attttgatca gaatgttaaa gataactctg gctggttatc
     9241 tattgcaagt atgggtgtac tgatagctgt tattttagcc atagtaaata agaggtatct
     9301 tgaatatgac ttatcgttta aaaacaatag aatgaaactg ttgagacgtg ttcagatcta
     9361 tcttgtcatt ccgttgtcta ttgctttact ggtgcatctt cagttaattc ctctggagat
     9421 agtttttagt aatattgcaa cttcagataa gagtgttaat ttcaaagtga tagctgaact
     9481 ggctttcatg tcatatttta tctttcttct gacaatgctt cctggagtca tttatctgaa
     9541 aatgaatcca cagcataaat tttcaaaaag aattagctat tcatttatcg catccttgat
     9601 gttattatta ataatatcga ctcaaataac cgtgttacca gtgattttta cccattccgt
     9661 tattaagcta tcaggtataa gtgacttcaa aatacatagc tacattatta aaacaagtga
     9721 atatcctgaa gagttttttt ccaatgcagc atgggataaa aaaaatataa aaccggggga
     9781 ttattactct gtgcaggctg tttctatgtt tacgacaaac cagtttattc tcctttgtcc
     9841 taaggatatt ataaagtttt atcgggaaag ctggaagttc gagttgctta atgtagactt
     9901 cgatataaat accaggaaga aactccagga agaagctgca tattgcgtac caatttctgc
     9961 aatatctgta aaacgatggg atatgcctct tcagggctcg aaaccctcaa gttagaaggc
    10021 aactagggcg actgtattct gtgacgaaat gaatggctgg ctcactataa taatgagcga
    10081 acccatcagg gaaaaatgtg caatgggcgg acgccaatgg aaacgttact cgatggaaaa
    10141 cgcatctggg ccgagaaaaa tttaagccag atgtaatctg acagatacct gtataaataa
    10201 ccgataactg tcagatcagg tctgagctaa tacatttcaa taaaggtact tgctcgcgct
    10261 ctgtcatttt ctgaaactct tcatgctgca tttcgatttt ccttctaaga tcataactcg
    10321 catacctgtt ctttttatgt atatctatat ctatttttgt gacgagttca aaccacaatg
    10381 ttcgcgctcc ccatgcagcg ttatgaaaca tttccgcaac ggctatagag tctgtattaa
    10441 ctgcttcagt catgtagtcg ctaatacgtt cagcggtaat tttcgttatt tcatcgtaat
    10501 tcattttatc tcctacaagg tgatgctgcc aacttactga tttagtgtat gatggtgttt
    10561 ttgaggtgct ccagtggctt ctgtttctat cagctgtccc tcctggtttc agctactgac
    10621 ggggtggtgc gtaacggcaa aagcaccgcc ggacatcagc gctatctctg ctctcactgc
    10681 cgtaaaacat ggcaactgca gttcacttac accgcttctc aacccggtac gcaccagaaa
    10741 atcattgata tggccatgaa tggcgttgga tgccgggcaa ctgcccgcat tatgggcgtt
    10801 ggcctcaaca cgattttacg tcacttaaaa aactcaggcc gcagtcggta acctcgcgca
    10861 tacagccggg cagtgacgtc attgtctgcg cggaaatgga cgaacagtgg ggatacgtcg
    10921 gggctaaatc gcgccagcgc tggctgtttt acgcgtatga caggctccgg aagacggttt
    10981 ttgcgcacgt attcggtgaa cgcactatgg cgacgctggg gcgtcttatg agcctgctgt
    11041 caccctttga cgtggtgata tggatgacgg atggctggcc gctgtatgaa tcccgcctga
    11101 agggaaagct gcacgtaatc agcaagcgat atacgcagcg aattgagcgg cataacctga
    11161 atctgaggca gcacctggca cggctgggac ggaagtcgct gtcgttctca aaatcggtgg
    11221 agctgcatga caaagtcatc gggcattatc tgaacataaa acactatcaa taagttggag
    11281 tcattaccct cctacaagat tatttaatgg aatgcaaaat atctggtctg ataataatgt
    11341 tccagaatta atatctgcag gctatgttaa gttgtcccca cacacaatct acctgttttc
    11401 tcgtgtgtgc cacagacgca atacataaat agtctggcca ttaatttcgt aacggatttc
    11461 gtactcgcca gcaaaaatcc gtctgacctc cctgggttca aactgaaaca actgttctcc
    11521 catacgtgga tgagttaaca gaatgaccgg tgcctgtgtc agggactgta ccgtttctgg
    11581 cggcagcagg tttactggcc agcaccagaa aatcaaataa ccgcgacaaa tcagaaagcg
    11641 ccttactggt ccacttcagt tccatcagcg tggcaccggt aacggattgt cagtactgag
    11701 gctgtccgac caggcctgta cagcctgatg gtcgataacc tgtccggatg tcacatcgtc
    11761 cagggcttcc agcgtcaggc gattacgctc ctcctcctgg gcaagccatg cagaaagcgc
    11821 ctgtttgata acccagcccc gggaacgttc cagtctggcg gccatctggt cgactttatc
    11881 agccataggt aatggcacat gcgcggtaat tacttttgtt gcttgtgcgg cattgttttt
    11941 catttgcata tccgattagt tgttaatcat atttaatcat agtgattact ttcagacgga
    12001 acaaggcaaa taatgcgcgt cagcgcatgt aaggcggcat acggaggtta catgtagcac
    12061 aggtgtaaaa ccgccgaagc ccggcgtaag ccggtactga ttgatagatt tcaccttacc
    12121 cttttccatc ctgctaagcc acacccgctt tcagctatga gagagccttt gtgcgcagtc
    12181 ggggcgtatc tccgcgttag cgggccgtga gggacgctta cgagcgtgga tgagagacgt
    12241 acagtggttt cttctagctt ttatttcctc tcaggtcccg aattgtcaac ttctgaatcg
    12301 tgggggcccc tttggggtga cgattcagtg gttgacaact gcacataaaa caccctgtgt
    12361 gtggggtgat ggttcacgta gtggtccatc gccctgccag gggtcagtcg ccactacacc
    12421 atcacttgag aaagagaagg ggcactgttg caaatagtcg gtggtgataa acttatcatc
    12481 cctttttgct gatggagctg cacatgaacc cattcaaagg ccggcatttt cagcgtgaca
    12541 tcattctgtg ggccgtacgc tggtactgca aatacggcat cagttaccgt gagctgcagg
    12601 agatgctggc tgaacgcgga gtgaatgtcg atcactccac gatttaccgc tgggttcagc
    12661 gttatgcgcc tgaaatggaa aaacggctgc gctggtactg gcgtaaccct tccgatcttt
    12721 gcccgtggca catggatgaa acctacgtga aggtcaatgg ccgctgggcg tatctgtacc
    12781 gggccgtcga cagccggggc cgcactgtcg atttttatct ctcctcccgt cgtaacagca
    12841 aagctgcata ccggtttctg ggtaaaatcc tcaacaacgt gaagaagtgg cagatcccgc
    12901 gattcatcaa cacggataaa gcgcccgcct atggtcgcgc gcttgctctg ctcaaacgcg
    12961 aaggccggtg cccgtctgac gttgaacacc gacagattaa gtaccggaac aacgtgattg
    13021 aatgcgatca tggcaaactg aaacggataa tcggcgccac gctgggattt aaatccatga
    13081 agacggctta cgccaccatc aaaggtattg aggtgatgcg tgcactacgc aaaggccagg
    13141 cctcagcatt ttattatggt gatcccctgg gcgaaatgcg cctggtaagc agagtttttg
    13201 aaatgtaagg cctttgaata agacaaaagg ctgcctcatc gctaactttg caacagtgcc
    13261 ctgcggagca aggccgtcgc gaacgagtgg cggagggtgt gcggtgtggc gggcttcgtg
    13321 atgcctgctt gttctacggc acgtttgaag gcgcgctgaa aggtctggtc atacatgtga
    13381 tggcgacgca cgacaccgct ccgtggatcg gtcgaatgcg tgtgctgcgc aaaaacccag
    13441 aaccacggcc aggaatgccc ggcgcgcgga tacttccgct caagggcgtc gggaagcgca
    13501 acgccgctgc ggccctcggc ctggtccttc agccaccatg cccgtgcacg cgacagctgc
    13561 tcgcgcaggc tgggtgccaa gctctcgggt aacatcaagg cccgatcctt ggagcccttg
    13621 ccctcccgca cgatgatcgt gccgtgatcg aaatccagat ccttgacccg cagttgcaaa
    13681 ccctcactga tccgcatgcc cgttccatac agaagctggg cgaacaaacg atgctcgcct
    13741 tccagaaaac cgaggatgcg aaccacttca tccggggtca gcaccaccgg caagcgccgc
    13801 gacggccgag gtcttccgat ctcctgaagc cagggcagat ccgtgcacag caccttgccg
    13861 tagaagaaca gcaaggccgc caatgcctga cgatgcgtgg agaccgaaac cttgcgctcg
    13921 ttcgccagcc aggacagaaa tgcctcgact tcgctgctgc ccaaggttgc cgggtgacgc
    13981 acaccgtgga aacggatgaa ggcacgaacc cagtggacat aagcctgttc ggttggtaag
    14041 ctgtaatgca agtagcgtat gcgctcacgc aactggtcca gaaccttgac cgaacgcagc
    14101 ggtggtaacg gcgcagtggc ggttttcatg gcttgttatg actgtttttt tgtacagtct
    14161 atgcctcggg catccaagca gcaagcgcgt tacgccgtgg gtcgatgttt gatgttatgg
    14221 agcagcaacg atgttacgca gcagggcagt cgccctaaaa caaagttagc catatgaact
    14281 cggaatcagt acgcatttat ctcgttgctg cgatgggagc caatcgggtt attggcaatg
    14341 gtcctaatat cccctggaaa attccgggtg agcagaagat ttttcgcaga ctcactgagg
    14401 gaaaagtcgt tgtcatgggg cgaaagacct ttgagtctat cggcaagcct ctaccgaacc
    14461 gtcacacatt ggtaatctca cgccaagcta actaccgcgc cactggctgc gtagttgttt
    14521 caacgctgtc gcacgctatc gctttggcat ccgaactcgg caatgaactc tacgtcgcgg
    14581 gcggagctga gatatacact ctggcactac ctcacgccca cggcgtgttt ctatctgagg
    14641 tacatcaaac cttcgagggt gacgccttct tcccaatgct caacgaaaca gaattcgagc
    14701 ttgtctcaac cgaaaccatt caagctgtaa ttccgtacac ccactccgtt tatgcgcgtc
    14761 gaaacggcta accattccgt caacgggacg ccaaaatgct gcgcattttg gttccctccg
    14821 ctgcgctccg gctctcgtta cgtccaacgt tagcaccact taaacccagc tttatttagc
    14881 tcatgtttat tcaaacggca tttagctttt caggcgttat tcagtgcctg ttttgccttt
    14941 ttccgggctt cgcctgcatg ggctgcgcag gttttcagtc tttttggcct ctagcccttg
    15001 cgtagcaagc gcaagcagct atcgtttttg cagtgctgtg ccgcctcggt ggcgcagcgt
    15061 tttttcacgg ttagcgcccg tcgccaaatt caagttatcc gttttggctt ctggttctaa
    15121 catttcggtc aagccgaccc gcattctgcg gtcggcttac ctcgcccgtt agacatcatg
    15181 agggaagcgg tgaccatcga aatttcgaac caactatcag aggtgctaag cgtcattgag
    15241 cgccatctgg aatcaacgtt gctggccgtg catttgtacg gctccgcagt ggatggcggc
    15301 ctgaagccat acagcgatat tgatttgttg gttactgtgg ccgtaaagct tgatgaaacg
    15361 acgcggcgag cattgctcaa tgatcttatg gaggcttcgg ctttccctgg cgagagcgag
    15421 acgctccgcg ctatagaagt cacccttgtc gtgcatgacg acatcatccc gtggcgttat
    15481 ccggctaagc gcgagctgca atttggagaa tggcagcgca atgacattct tgcgggtatc
    15541 ttcgagccag ccatgatcga cattgatcta gctatcctgc ttacaaaagc aagagaacat
    15601 agcgttgcct tggtaggtcc ggcagcggag gaattctttg acccggttcc tgaacaggat
    15661 ctattcgagg cgctgaggga aaccttgaag ctatggaact cgcagcccga ctgggccggc
    15721 gatgagcgaa atgtagtgct tacgttgtcc cgcatttggt acagcgcaat aaccggcaaa
    15781 atcgcgccga aggatgtcgc tgccgactgg gcaataaaac gcctacctgc ccagtatcag
    15841 cccgtcttac ttgaagctaa gcaagcttat ctgggacaaa aagaagatca cttggcctca
    15901 cgcgcagatc acttggaaga atttattcgc tttgtgaaag gcgagatcat caagtcagtt
    15961 ggtaaatgat gtctaacaat tcgttcaagc cgaccgcgct acgcgcggcg gcttaactcc
    16021 ggcgttagat gcactaagca cataattgct cacagccaaa ctatcaggtc aagtctgctt
    16081 ttattatttt taagcgtgca taataagccc tacacaaatt gggagatata tcatgaaagg
    16141 ctggcttttt cttgttatcg caatagttgg cgaagtaatc gcaacatccg cattaaaatc
    16201 tagcgagggc tttactaagc ttgccccttc cgccgttgtc ataatcggtt atggcatcgc
    16261 attttatttt ctttctctgg ttctgaaatc catccctgtc ggtgttgctt atgcagtctg
    16321 gtcgggactc ggcgtcgtca taattacagc cattgcctgg ttgcttcatg ggcaaaagct
    16381 tgatgcgtgg ggctttgtag gtatggggct cataattgct gcctttttgc tcgcccgatc
    16441 cccatcgtgg aagtcgctgc ggaggccgac gccatggtga cggtgttcgg cattctgaat
    16501 ctcaccgagg actccttctt cgatgagagc cggcggctag accccgccgg cgctgtcacc
    16561 gcggcgatcg aaatgctgcg agtcggatca gacgtcgtgg atgtcggacc ggccgccagc
    16621 catccggacg cgaggcctgt atcgccggcc gatgagatca gacgtattgc gccgctctta
    16681 gacgccctgt ccgatcagat gcaccgtgtt tcaatcgaca gcttccaacc ggaaacccag
    16741 cgctatgcgc tcaagcgcgg cgtgggctac ctgaacgata tccaaggatt tcctgaccct
    16801 gcgctctatc ccgatattgc tgaggcggac tgcaggctgg tggttatgca ctcagcgcag
    16861 cgggatggca tcgccacccg caccggtcac cttcgacccg aagacgcgct cgacgagatt
    16921 gtgcggttct tcgaggcgcg ggtttccgcc ttgcgacgga gcggggtcgc tgccgaccgg
    16981 ctcatcctcg atccggggat gggatttttc ttgagccccg caccggaaac atcgctgcac
    17041 gtgctgtcga accttcaaaa gctgaagtcg gcgttggggc ttccgctatt ggtctcggtg
    17101 tcgcggaaat ccttcttggg cgccaccgtt ggccttcctg taaaggatct gggtccagcg
    17161 agccttgcgg cggaacttca cgcgatcggc aatggcgctg actacgtccg cacccacgcg
    17221 cctggagatc tgcgaagcgc aatcaccttc tcggaaaccc tcgcgaaatt tcgcagtcgc
    17281 gacgccagag accgagggtt agatcatgcc tagcattcac cttccggccg cccgctaaat
    17341 atctcctttt gggttgttaa taaaacatcc aataagttga ctgtgcgtga aaaagaaagt
    17401 tttgtgtgat ggcgttgaag atcgcaccgt taagctctta tgtgggatgg tgcagagctc
    17461 gacgactacc gataaaacgc aaccgccgca aacagacaag aaaaagcccc aactgataac
    17521 agttggggct tcagtattgt gattggtgga gcaatagcac cctgaaccca aaaccttctc
    17581 gctcaaccgg tagtggctga taacaactcg tgagggctat tgcgggttaa gcatttagcg
    17641 atgtctaggg ccagactgga cgtctgaacg caagccgctg atactgtaca taaccacagt
    17701 atcagcggag gatacccatg tcgctggcaa ggaacgccac ggcgagtcaa tcgcccactc
    17761 aaacaaacgg ttacgaacgc caccaacccg accagacgct gctctaccag ctggttgagc
    17821 agcactaccc agccttcaaa gcctcactcg aagcccaagg tcaacacctg cctcgctaca
    17881 tccaacaaga attcaacgac ctcctccaat gtggccgtct ggagtatggt ttcatgcggg
    17941 ttcgctgcga ggattgtcat cacgagcgtc tggtcgcctt cagctgtaaa cgacgcggct
    18001 tttgccctag ctgcggtgcc cgccggatgg ccgagagtgc ggcgctgctg atagacgaag
    18061 tcttccccaa ggagcccatt cgccagtggg tgctcagctt tcctttccag ctacgctttt
    18121 tgctggctcg ccatccccag ctgatgggcc aggtcttgag tatcgtctat cgtacactct
    18181 caactcatct gatcaaaaaa gccggttaca ccaaagcctc tgcacaaact ggctcagtga
    18241 ctcttatcca acgctttggc tccgcgctaa atctcaatgt ccactaccac atgctgtttc
    18301 tcgatggtgt ctatgccgaa gatgactatg gcaagcaacg cttccatcgt gtcaaggcac
    18361 ccacttacga tgagctgaat acgctcgctc acaccctcag ccatcgcatc gctcgctgca
    18421 tggaaaagcg tgggattttg gagcgtgatg ccgagaatac gtggttgaca ctggaagagg
    18481 gcgaagacga tacgctgact caattacatg gtgcttcggt tacgtatcgc attgccgtcg
    18541 gcccccagca agggcgcaaa gtcttcaccc tgcaaacctt gccagggcgt gaggataaag
    18601 ccgactcaag cagtcgagta gccaaccatg ctggtttctc gctacacgcc ggtgtgatgg
    18661 ccgaagcgca tcagcgggat aagcttgagc gcttgtgtcg ctacattagt cggccagcgg
    18721 tttcagaaaa acgtctggca ttaaccgcca atgggcaggt gcgttacgag ctcaaaactc
    18781 cgtaccgcaa tggcaccacc catgtgatct tcgagccgct ggacttcatc gccaaactcg
    18841 ctgcgttggt acctaagccg cgagtcaacc tcacacgctt ccacggcgtc tttgcaccga
    18901 acagcaaaca ccgagttcaa gtaacacccg ccaagcgggg caagaagccc gacaaatcgg
    18961 aaggtctcga tactaactgg cgtgacaaga gtcctgcaga gcgccaccgc gccatgacct
    19021 ggatgcaacg cctcaagcga gtcttcaata ttgatattga agtctgcgaa cactgcggcg
    19081 gtcacgtcaa agtgattgcc agcatcgaag atccgaaggt cattgagcag attctcaagc
    19141 atctgaaaca gaaaacagcc aaggcgaatg ccgccaagca gcgtgagctg ccaccagaac
    19201 gagcgccgcc actgactccc agcctgttcg atccatcaca gagtcgtctc tttgactgac
    19261 gaccccaaat ccaacactgc tcaacactgc caacttttaa acggggcggt ggggcagttt
    19321 gtatctctcg agctatcagg ctagagattt taccgccaaa tcgaacctta ttagagcggt
    19381 ttaggctgga ccggcagtta aaattggggc ttgagcggta aacgagtgag ggaatttcag
    19441 gtaagatact tcggatgagg agcaaaaagg tggtttatac ttcctatacc cgctcgcggt
    19501 cgaagccgcg tccggcctgc ccgaatacct gcaatggctg gccgccgaga gccgaccggt
    19561 aaactgagcc aatgaccgca tccacgatcc gcctgcgccg ctggctggcc gggctcgccc
    19621 tgctgcttgc gctgcccgcg acctcggccg tcgcccagga cttcgaactg ccgccggtcg
    19681 acgaggtctt cgtcctgtcc gcgcaggcca ccgcgccgga ccgcatcgag gtgcgctggc
    19741 ggatcgccga cggctattac ctgtaccggc accgcacctc ggtcaaggcc gatgccgcct
    19801 tcaccggcgc gaccatggcg ctgccgaagg gcaaggccta ccgcgacgaa ttcttcggcg
    19861 acgtcgaaac ctaccgcaag gaattgctcg gcaccctcac cggcacgccc gcggccggcg
    19921 cgagcgcgac caccctgacc gtgaagtacc agggctgcgc cgatgccggc gtgtgctacc
    19981 cgccgcagac ccgcaccctg aaggtcgcgt tgccgggcga agcgggcgct ggcggcttcg
    20041 gctgtaaggc gcgcgggctg catgattatg tcgtcaagaa cggctctgcc gatcatccca
    20101 acgccgaggt gaaattcgca ctgggtgatg tggtcaacac catgatcggc tgcactaatg
    20161 gtgaaacgat catgctgtgc cacgacacct cgctgccgcg cccctattct ctcggctttc
    20221 gggtgcaagg caccgagggg ctgtggatgg acgtcaacaa gtcgatctat ctggagggca
    20281 agagcccaca gccgcaccgc tgggagcctg ccgagggctg gtttgcgaaa tacgatcacc
    20341 cgctatggaa acgctacgcc gatctggcgg caggggccgg gcatggcggg atggactggt
    20401 tcgtgatcca cgcttttgtc gaggcgctga aggccaaggc cccgatgcca atcgacattt
    20461 acgacgcgct ggcctggagc gcgatcacgc ctctgtcgga acaatcgatt gctgagggca
    20521 atcgcacgtt agattttccc gacttcaccc gagggcagtg gcgcacccgc aagccgatct
    20581 ttgcgctgaa cgacgcctat tgatcgacgc gatttaggcc aagcgcaccg caaaggcgaa
    20641 attggtaatc ttgtcggtat ccttgacgcc cggcgcgctt tcgacgccgc tggaggtatc
    20701 gaccagcggc gctccggtgc gcgcaatcgc ctcggcaaca ttcgtcggat ttagcccgcc
    20761 tgccagcccc cacggcaagg caccgcgata tccggccagc agcgaccagt cgaacgccaa
    20821 ccccatgccg ccgggcagcg cgcctttggg ggtcttggcg tcgaacaaga tcaagtccgc
    20881 cgccccggca taggctgcgg cgcgtgcgac atcgctggcg ctggcgacgg gcagcgcctt
    20941 ccacaccggc ttgccaaacc gcgcgcgcaa ctgggccacg cgttcgggcg attccgaacc
    21001 gtgcagctgc agcgcgttca gcttggctgc caccagtgcg tcggcgatga cagcatcatc
    21061 cgcatcgacg aacaaaccga ccatggcgat ctggccagct gcgcgcgatg tcaaagcgcc
    21121 cgcgacattc gacgtaaccg cacggggcga cgctggatag aacaccaacc cggcatagtc
    21181 cgcccgcgcc gcgatggtcg catcgagcgc ctcgggtgtg ctgatcccgc aaatcttgat
    21241 tttcgcgggc atgcggtcag tcggggttct ggatcagccg caccagcgtg cagtcgggat
    21301 cgatcaggta gccgatcctc aggccgctcg cctccagttg cggagctttg aagcgcggcc
    21361 agccggtgct ttttcctcgg ctcccgccgc gttcaccaat gccaccatgg catcgagatc
    21421 atccaaccgc aggcaacagc cgaacgagct cgtagctggg tcgaggtcag gataggggaa
    21481 gaattcgagc tgcaaaccgc cgcgctgcag gatcatccag ccgcgatcct tccaactcgt
    21541 cgcaaagccc agcttcgcat aaaacgcctc tgtcacatcg aaatcgcgcg atggcagatt
    21601 gggggtgacg tggtcagcca tggctcagcg cagcttgtcg gccatgcggg ccgtatgagt
    21661 gattgcggcg cggctatcgg gggcggaatg gctcatcacg atcatgctgg ccttggggaa
    21721 cgccgcacca aacgcgcgcg ctgacgcggc gtagtgctca gtgtcggcat caccgagatt
    21781 gccgagcgac ttggccttgc tgtccttgat caggcagcca ccaaaagcga tgtcggtgcc
    21841 gtcgatccca acggtgatat tgtcactggt gtggccgggg ccggggtaaa ataccttgag
    21901 cgggccaaag ttgggcgcgg ttgctggttc gacccagcca ttggcggcga aagtcaggct
    21961 gtgttgcgcc gcaaccagcc cctcttgcgg ggcaagctgg ttcgacaacg cattggcata
    22021 agtcgcaatc cccgccgcat gcagcgcgtc cataccgccc atcttgtcct gatgcgcgtg
    22081 agtcaccacc gccagcgcga ccggcaggtt gatctcctgc ttgatccagt tgaggatctg
    22141 ggcggtctgg tcatcggtcc aggcggtatc gaccaacagc acgcggccgc catccctgac
    22201 gatcaaaccg ttggaagcga ctgccccgaa acccggcatg tcgagatagg aagtgtgctg
    22261 ccagacattc ggtgcgagct ggcggaaaac cagatcgcca aaccgttggt cgccagtttc
    22321 catttgctgg ccaatcgtcg ggcggatttc accgggcatg cacccgctca gcatcaatgc
    22381 agcggctaat gcggtgctca gcttcgcgac cgggtgcata atattgggca attccatcaa
    22441 gttttccttt tattcagcat taaaaacccc gcaaatgcga ggcctagtaa atagatgatc
    22501 ttaatttggt tcactgtagc aaaaatatgg ggcgaattca aacatgaggt gcgacagttt
    22561 caaaagccat atgataatca acaagctgag caaatttctc taatggtgta agccaatcta
    22621 acgcctttct aggacgagta ttcagtgaca tggcaacttg atttaaataa tgctgatctg
    22681 cctgatttaa atcaatccct ttaggtaaat attgcctaat taaaccattc atattttcgc
    22741 atgtgccttt ttgccagggt gaatgtgggt cacagaaata tacatctatg cctaaatctt
    22801 cttcgagtat tttatgttga gcacttttct ttcacccaat gggtgaaagc tgaatttcga
    22861 aggaatgcat atttatcaag gctttgatta tgctttttga agtactgacg tagaatctag
    22921 gtatgagtaa acggcactgt tgcaaatagt cggtggtgat aaacttatca tccccttttg
    22981 ctgatggagc tgcacatgaa cccattcaaa ggccggcatt ttcagcgtga catcattctg
    23041 tgggccgtac gctggtactg caaatacggc atcagttacc gtgagctgca ggagatgctg
    23101 gctgaacgcg gagtgaatgt cgatcactcc acgatttacc gctgggttca gcgttatgcg
    23161 cctgaaatgg aaaaacggct gcgctggtac tggcgtaacc cttccgatct ttgcccgtgg
    23221 cacatggatg aaacctacgt gaaggtcaat ggccgctggg cgtatctgta ccgggccgtc
    23281 gacagccggg gccgcactgt cgatttttat ctctcctccc gtcgtaacag caaagctgca
    23341 taccggtttc tgggtaaaat cctcaacaac gtgaagaagt ggcagatccc gcgattcatc
    23401 aacacggata aagcgcccgc ctatggtcgc gcgcttgctc tgctcaaacg cgaaggccgg
    23461 tgcccgtctg acgttgaaca ccgacagatt aagtaccgga acaacgtgat tgaatgcgat
    23521 catggcaaac tgaaacggat aatcggcgcc acgctgggat ttaaatccat gaagacggct
    23581 tacgccacca tcaaaggtat tgaggtgatg cgtgcactac gcaaaggcca ggcctcagca
    23641 ttttattatg gtgatcccct gggcgaaatg cgcctggtaa gcagagtttt tgaaatgtaa
    23701 ggcctttgaa taagacaaaa ggctgcctca tcgctaactt tgcaacagtg ccggattgaa
    23761 tataaccgac gtgactgtta catttaggtg gctaaacccg tcaagccctc aggagtgaat
    23821 catgaccgta gtcacgaccg ccgatacctc ccaactgtac gcacttgcag cccgacatgg
    23881 gctcaagctc catggcccgc tgactgtcaa tgagcttggg ctcgactata ggatcgtgat
    23941 cgccaccgtc gacgatggac gtcggtgggt gctgcgcatc ccgcgccgag ccgaggtaag
    24001 cgcgaaggtc gaaccagagg cgcgggtgct ggcaatgctc aagaatcgcc tgccgttcgc
    24061 ggtgccggac tggcgcgtgg ccaacgccga gctcgttgcc tatcccatgc tcgaagactc
    24121 gactgcgatg gtcatccagc ctggttcgtc cacgcccgac tgggtcgtgc cgcaggactc
    24181 ggaggtcttc gcggagagct tcgcgaccgc gctcgccgcc ctgcatgccg tccccatttc
    24241 cgccgccgtg gatgcgggga tgctcatccg tacaccgacg caggcccgtc agaaggtggc
    24301 cgacgacgtt gaccgcgtcc gacgcgagtt cgtggtgaac gacaagcgcc tccaccggtg
    24361 gcagcgctgg ctcgacgacg attcgtcgtg gccagatttc tccgtggtgg tgcatggcga
    24421 tctctacgtg ggccatgtgc tcatcgacaa cacggagcgc gtcagcggga tgatcgactg
    24481 gagcgaggcc cgcgttgatg accctgccat cgacatggcc gcgcacctta tggtctttgg
    24541 tgaagagggg ctcgcgaagc tcctcctcac gtatgaagcg gccggtggcc gggtgtggcc
    24601 gcggctcgcc caccacatcg cggagcgcct tgcgttcggg gcggtcacct acgcactctt
    24661 cgccctcgac tcgggtaacg aagagtacct cgctgcggcg aaggcgcagc tcgccgcagc
    24721 ggaagcagcg gaatgagcga acgtcgatat agcccgctcg cgacgctgtt cgcggcgacc
    24781 tttctcttcc ggatcggcaa cgcggtggcg gccctcgcgc ttccatggtt cgtcctgtct
    24841 catacaaaga gcgcggcctg ggcgggcgcc acggccgcta gcagcgtcat cgcgaccatc
    24901 atcggcgcgt gggttggtgg tggcctcgtc gatcggttcg ggcgcgcgcc cgtcgcattg
    24961 atctcgggtg tggtgggcgg cgtggccatg gcgagcatcc cactgctcga tgccgttggc
    25021 gccctctcga acactgggct gatcgcttgc gtggtgctcg gtgccgcgtt cgacgcaccc
    25081 ggtatggccg cgcaggacag tgagctgccc aaactcggcc acgtcgccgg gctctccgtt
    25141 gagcgcgtct cgtcactgaa agcggtgatc gggaacgtcg cgattctagg tggcccggcc
    25201 cttgggggcc gcaatcggcc tgcttggcgc tgcgccaacg ctcgggctga cggcgttctg
    25261 ctccgtcctt gcaggtctgc tcggcgcgtg ggtgcttccc gcgcgtgccg ctcggacgat
    25321 gaccacgacg gcgactctct ccatgcgcgc cggcgtcgct tttctctgga gcgaacccct
    25381 gctgcgccct ctctttggta tagtgatgat cttcgtgggc atcgttggcg ccaacggcag
    25441 cgtcatcatg cctgcgctgt ttgtagatgc aggacgccaa gtagcagagc tcgggctgtt
    25501 ctcctcaatg atgggggctg gtggtctcct tggcattgcc attcatgcgt cggtcggcgc
    25561 ccggatatca gcgcagaact ggctggcggt ggcattttgt ggctctgcgg tgggctcgct
    25621 tctgctttca cagttgccag gcgtgccggt gctgatgttg ttgggcgcgc tcgtgggact
    25681 gctgaccggc tcagtctctc ccattctcaa cgctgccatc tacaaccgca cgccgccaga
    25741 acttctcggc cgggtactcg gcacggtctc ggcggtgatg ctgtcagcct cgcccatggt
    25801 tatgcttgcg gccggcgcgt ttgtcgacct tgctggtccg ctccctggcc tcgttgtatc
    25861 ggccgtgttt gcggggctcg tggctctact ctcgctccgt cttcaatttg ctacaatggc
    25921 ggcggcagcc acagcctccg ccccaaccca tacagaaggt gaacactgat gcccgcccca
    25981 agctcaagtc cgatgacgag gtactcgagg ccgccaccgt agtgctgaag cgttgcggtc
    26041 ccatagagtt cacgctcagc ggagtagcaa aggaggtggg gctctcccgc gcagcgttaa
    26101 tccagcgctt caccaaccgc gatacgctgc tggtgaggat gatggagcgc ggcgtcgagc
    26161 aggtgcggca ttacctgaat gcgataccga taggcgcagg gccgcaaggg ctctgggaat
    26221 ttttgcaggt gctcgttcgg agcatgaaca ctcgcaacga cttctcggtg aactatctca
    26281 tctcctggta cgagctccag gtgccggagc tacgcacgct tgcgatccag cggaaccgcg
    26341 cggtggtgga ggggatccgc aagcgactgc ccccaggtgc tcctgcggca gctgagttgc
    26401 tcctgcactc ggtcatcgct ggcgcgacga tgcagtgggc cgtcgatccg gatggtgagc
    26461 tagctgatca tgtgctggct cagatcgctg ccatcctgtg tttaatgttt cccgaacacg
    26521 acgatttcca actcctccag gcacatgcgt aaacggaggt gtgcagagtc cctgcggcag
    26581 gcgacgaaca cgaccgtcgt cgattagtac cggtacggtc ggtggtatcg aagtcttgat
    26641 caccactcag gtctacggct tacaaatggt gaccatcccg atacttgcgt cagagcaccg
    26701 ggccgattct ttgacagtga atcactcccg taaggttgtg ccggtgtggg tgtcccgggt
    26761 cgagacgata ctccgccaat gcgcccagca aacaacctgg ccatcgcagg tggtggggag
    26821 cggtgtggcg gatgagttgg acaagttggt gtagcagcac gagcacggcg agataacatc
    26881 gcaggagttc gacatgctca agagacagct gattgcgaat cgcgatgcag attcataacc
    26941 cgattgcggg ttggcttcac tccaccatca ccgagcagac tagcacggcg ggctctgttg
    27001 caaagattgg cggcagtcag aggtaggctg tcgctctgcg ccgatcaggc ggctgctgcg
    27061 aaatggtggt tgagcatgcc catggcctcc gtcagcgccg agggcccaat gccaaaagct
    27121 ctctccacaa ggcgcacctc gcccctgatg ccgggctgca ggcaccaggg gcgagcctgt
    27181 cctttgcgca gggctcgcat gacttcgaat cccttgatcg tggcataggc cgtggggatc
    27241 gatttgaaac cgcgcaccgg cttgatcagt atcttgagct ttccgtgatc ggcctcgatc
    27301 acgttattga gatacttcac ctgccggtgg gccgtctccc ggtccagctt tccttcgcgc
    27361 ttcaattcgg tgatcgctgc accatagctc ggcgctttgt cggtattgag cgtggcaggc
    27421 ttttcccagt gcttcaggcc tcgcagggcc ttgcccagga accgcttcgc tgccttggcg
    27481 ctgcgggtcg gcgacaggta gaaatcgagg cactgttgca aagttagcga tgaggcagcc
    27541 ttttgtctta ttcaaaggcc ttacatttca aaaactctgc ttaccaggcg catttcgccc
    27601 aggggatcac cataataaaa tgctgaggcc tggcctttgc gtagtgcacg catcacctca
    27661 atacctttga tggtggcgta agccgtcttc atggatttaa atcccagcgt ggcgccgatt
    27721 atccgtttca gtttgccatg atcgcattca atcacgttgt tccggtactt aatctgtcgg
    27781 tgttcaacgt cagacgggca ccggccttcg cgtttgagca gagcaagcgc gcgaccatag
    27841 gcgggcgctt tatccgtgtt gatgaatcgc gggatctgcc acttcttcac gttgttgagg
    27901 attttaccca gaaaccggta tgcagctttg ctgttacgac gggaggagag ataaaaatcg
    27961 acagtgcggc cccggctgtc gacggcccgg tacagatacg cccagcggcc attgaccttc
    28021 acgtaggttt catccatgtg ccacgggcaa agatcggaag ggttacgcca gtaccagcgc
    28081 agccgttttt ccatttcagg cgcataacgc tgaacccagc ggtaaatcgt ggagtgatcg
    28141 acattcactc cgcgttcagc cagcatctcc tgcagctcac ggtaactgat gccgtatttg
    28201 cagtaccagc gtacggccca cagaatgatg tcacgctgaa aatgccggcc tttgaatggg
    28261 ttcatgtgca gctccatcag caaaagggga tgataagttt atcaccaccg actatttgca
    28321 acagtgccct atttttcggg gatctgattg ccctctggca atatcattca gcacgccata
    28381 gtcggcatca tggtccattc gccagaaaac cgaagcaccg gcatcagcca ggcgtggaga
    28441 aaactggtat cccagcagcc agaaaaggcc aaagacaagt tcgctggcac ctgctgtatc
    28501 ggtcataatt tcggttggat tcagcccggt ctcctgttcc agaagacctt ccagcacaaa
    28561 gatagagtcc ctcagcgtcc ccggtataac gatgccatga aagccggaat actgatcgga
    28621 cacaaagttg taccaggtga tccctctgtt attaccaaag tatttgcggt tcggtccggc
    28681 attgattgtt ctgactggcg taacaaagcg cattccatct gcagatgcca cttctcctcc
    28741 accccatatc tgtgccagtg gcagcgttgc ctgaaaatca accagtctgg cattagcgct
    28801 ggtgatagtt tcagcccgca gatagttcgc ttttgtccag ttcagccggt gtcgggtcag
    28861 tgcaggaaca tttgatctga tcagtggttc cagaccgata ttgcaggctt cagccatcag
    28921 cacggcgctg atgctgacgg gcagatcatc aactctggca ctggcttcac tagcatggaa
    28981 aaactcatca gcaaatccgg tatgggcgtt aatttcgagc agcaactccg ttaaatccac
    29041 cggagggagt agatcactga tcattttgct cagtcgtttc agactgtccg gctcatcaag
    29101 actggcgagg ggagaaattg tcaaccgggg cttcgggcca gaaacatcga gttcgacagc
    29161 ctcattttcg caaagacgtg cagcaacctg tctgtaacga ctatcaagct gatgacccag
    29221 agattttatt gcttcctgcg ggtctgtcgg gtgccccaaa gaacgataaa ccttaatccg
    29281 gtttgcctgc cagtcagcac cctgtagtaa tcttgcacga ggatctcccc accggttact
    29341 gccggtaacg tagacatccc tccgcctcag actatcctgc agtttactga gaaagcagag
    29401 cgtgtatccc ctgcgggtga tatgtttttc cttgttaatc accagccgtt tccatgaccg
    29461 actgataatt tccgttggtg cgtcgtcaaa aaactgccgc cgtgagctga actcccggct
    29521 gaggtagtca caggcattca gagtggtaac cccggcaggt gcggatgaaa atttaacggt
    29581 attcagcaga tggggcagga aacgacgaac gcgcccgtac tgctccacca tttcttcatg
    29641 aaaattatcg tctgagggcc gggcaatttc acggacaagc gtgatgattt cagccagctt
    29701 ttgccttggg atgtagctga acacctcagc acgaatcgat tcgtccggtg tttcttcttt
    29761 cagcaggtac gaacatgcgc tggcgagcgc caatgcagat ttatccagat ccttcagcga
    29821 gcggagccgt tttttctgcc caatctttct ggcgtcacgg atgataacgg ccagcatggc
    29881 gtccagaacg tccaatgcat catccagcgc cagcgtttcc atgcaaggac aaaggcaacc
    29941 agaaccgcca tccttttctg cggtgacatc ctggcaatat tgaacaccga agtcatacca
    30001 gcataacgtg cgagattttt caggcgcaca gccgggagtg tactcaggtt ttcagcatgc
    30061 aggccaaaat cgttcagagt tttccagcgt tcaattgctt cattaaacgc cggaccactg
    30121 atggtcacag ggcccttttt cagtgattcc agtaaagaca ggcggctgca atcagttggc
    30181 cccagcagca tctccagctg tgaacgctgt tcggctgacg gtatcagtgc cagtttgttc
    30241 cacaggcgca acgtcgcctt ttcccttacc tctgaaatca accgggtcag cgtagtggct
    30301 ccggggagaa taatacgatg ttgcataagc caccctgtcg ccagatcgaa aagcaggcca
    30361 ggacgttcgt tgcttatcca gctccgggta tataaaagac gggtaaggcg aaatgtccag
    30421 ggccaggcaa attcacgata ctgatagtgc tgacgtatca gcgctgcatg ctcacggcgg
    30481 gtattttccc tctgaccgta ttctgcaaga acggtgatat cacgaatccc gagctgtctg
    30541 gcggtaaaat gccggacgcc ggaaggaata tgacctggga cctacgtgcg cccgcaccga
    30601 caccctcaca ccttcgagct actgttgcca ttaaggggtc gtttcgtggt gctgaatttt
    30661 gacgatcggg gtaccgtcac ccatcgggcg atattggggg aaacctgtac ggtgctggag
    30721 atggccgcag gaacctggca tgccgtgctg tcgctggata ccggtggcat aatttttgaa
    30781 gtaaaacacg gtggctatca acccgtggct gccgatgact atgcgcactg ggctccagcg
    30841 gaaggagaac caggaaccac ggagcttatg gcctggtatg cgcaagcgca ggtgggcgac
    30901 agcacttttg ccgtctaagg cgataaacaa aaacggaatg agtttcccca ttccgtttcc
    30961 gctattacaa accgtcggtg acgattttag ccgccgacgc taatacatcg cgacggcttt
    31021 ctgccttagg ttgaggctgg gtgaagtaag tgaccagaat cagcggcgca cgatcttttg
    31081 gccagatcac cgcgatatcg ttggtggtgc catagccacc gctgccggtt ttatccccca
    31141 caacccagga agcaggcagt ccagcctgaa tgctcgctgc accggtggta ttgcctttca
    31201 tccatgtcac cagctgcgcc cgttggctgt cgcccaatgc tttacccagc gtcagattcc
    31261 gcagagtttg cgccattgcc cgaggtgaag tggtatcacg cggatcgccc ggaatggcgg
    31321 tgtttaacgt cggctcggta cggtcgagac ggaacgtttc gtctcccagc tgtcgggcga
    31381 acgcggtgac gctagccggg ccgccaacgt gagcaatcag cttattcatc gccacgttat
    31441 cgctgtactg tagcgcggcc gcgctaagct cagccagtga catcgtccca ttgacgtgct
    31501 tttccgcaat cggattatag ttaacaaggt cagatttttt gatctcaact cgctgattta
    31561 acagattcgg ttcgctttca cttttcttca gcaccgcggc cgcggccatc actttactgg
    31621 tgctgcacat cgcaaagcgc tcatcagcac gataaagtat ttgcgaatta tctgctgtgt
    31681 taatcaatgc cacacccagt ctgcctcccg actgccgctc taattcggca agtttttgta
    31741 tttacaacca cctttcaatc atttttgata aatcattgat ttcatctttg ctgcaatgat
    31801 acttaataaa ctctgcaagt tatccacaag agcaacacta aattttattg atgatattct
    31861 tattatacca gacattttca tacactccct tgtacggata attttccgac aacttcatga
    31921 ttacatatct tgcggttttg attatttttg ctgcaagaaa tacatacttc aaacga
//
