LOCUS       NZ_CP083807            20644 bp    DNA     circular CON 30-MAR-2024
DEFINITION  Staphylococcus argenteus strain 1801221 plasmid p2_1801121, complete
            sequence.
ACCESSION   NZ_CP083807
VERSION     NZ_CP083807.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN21514078
            Assembly: GCF_022370435.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus argenteus
  ORGANISM  Staphylococcus argenteus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20644)
  AUTHORS   Shittu,A.O., Layer,F., Strommenger,B., Nguyen,M.-T., Bletz,S.,
            Mellmann,A. and Schaumburg,F.
  TITLE     First report of a methicillin-resistant, high-level
            mupirocin-resistant Staphylococcus argenteus
  JOURNAL   Front Cell Infect Microbiol (2022) In press
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 20644)
  AUTHORS   Mellmann,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-SEP-2021) Inst. Hygiene, University Hospital Muenster,
            Robert-Koch-Str. 41, Muenster 48149, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 184.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022370435.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 14:28:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,734
            CDSs (total)                      :: 2,652
            Genes (coding)                    :: 2,573
            CDSs (with protein)               :: 2,573
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 40 of 79
            Pseudo Genes (incomplete)         :: 35 of 79
            Pseudo Genes (internal stop)      :: 27 of 79
            Pseudo Genes (multiple problems)  :: 16 of 79
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP083807.1.
            Bacteria and source DNA available from Robert Koch Institute,
            Wernigerode Branch, Dr. Birgit Strommenger (strommengerb@rki.de).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20644
                     /organism="Staphylococcus argenteus"
                     /mol_type="genomic DNA"
                     /strain="1801221"
                     /isolation_source="nasal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:985002"
                     /plasmid="p2_1801121"
                     /geo_loc_name="Germany: Heidelberg"
                     /collection_date="2018-04-18"
                     /collected_by="Robert Koch Institute"
     gene            complement(join(20218..20644,1..1331))
                     /gene="blaR1"
                     /locus_tag="LB317_RS13530"
                     /old_locus_tag="LB317_13540"
     CDS             complement(join(20218..20644,1..1331))
                     /gene="blaR1"
                     /locus_tag="LB317_RS13530"
                     /old_locus_tag="LB317_13540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer BlaR1"
                     /protein_id="WP_031788333.1"
                     /translation="MAKLLIMSVVSFCFIFLLLVFFRYILKRYFNYSLNYKVWYLTVLA
                     GLIPFIPIKFSFIKFNNVNNQAPTVESKSHDLNHNIITTKPVQEFATDIHKFNWDSIDN
                     ICTVIWIVLVIILSFKFLKALLYLKYLKKQSLYLNENEKNKIDTILFNHQYKKNIVIRK
                     AEAIQSPITFWYGKYIILIPSSYFKSVIDKRLKYIILHEYAHAKNRDTLHLIIFNIFSI
                     IMSYNPLVHIVKRKIIHDNEVEADRFVLNNINKNEFKTYAESIMDSVLKTSFFNKNILS
                     HSFNGKKSLLKNRLINIKEADLKKQSKLILIFICIFTFFIMIIQSQFLMGQSLTDYNYK
                     NPLQSDYQILDESKNFGSNSGSFVMYSMKKDKYYIYNEKESRKRYSPDSTYKIYLALFG
                     LDRHIISDKNSRMSWNHKHYLFESWNKEQDLNTAMQNSVNWYFERISNQIPKNYTAAQL
                     KQLNYGNENLGSYKSYWMEDSLKISNLEQVIVFKNMMEQNNHFSKKAKNQLSSSLLIKK
                     NEKYELYGKTGTGIVNGKYNNGWFVGYVITNHDKYYFATHLSDGNPSGKNAELISEKIL
                     KGMGVLNGQ"
                     /name="blaR1"
     gene            1438..2283
                     /gene="blaZ"
                     /locus_tag="LB317_RS13535"
                     /old_locus_tag="LB317_13545"
     ARG             1439..2280
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            2652..3185
                     /locus_tag="LB317_RS13540"
                     /old_locus_tag="LB317_13550"
     CDS             2652..3185
                     /locus_tag="LB317_RS13540"
                     /old_locus_tag="LB317_13550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823239.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001823239.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVVGNPLLDKFMKDLIIQILAMVSEQERNESK
                     RRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRIIYHRVVEMLEEGQSISKIAKEVNIT
                     RQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            3599..3892
                     /locus_tag="LB317_RS13545"
                     /old_locus_tag="LB317_13555"
     CDS             3599..3892
                     /locus_tag="LB317_RS13545"
                     /old_locus_tag="LB317_13555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            3967..5901
                     /locus_tag="LB317_RS13550"
                     /old_locus_tag="LB317_13560"
     CDS             3967..5901
                     /locus_tag="LB317_RS13550"
                     /old_locus_tag="LB317_13560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            5905..6216
                     /locus_tag="LB317_RS13555"
                     /old_locus_tag="LB317_13565"
     CDS             5905..6216
                     /locus_tag="LB317_RS13555"
                     /old_locus_tag="LB317_13565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            6228..6854
                     /locus_tag="LB317_RS13560"
                     /old_locus_tag="LB317_13570"
     CDS             6228..6854
                     /locus_tag="LB317_RS13560"
                     /old_locus_tag="LB317_13570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            7092..7721
                     /gene="mobV"
                     /locus_tag="LB317_RS13565"
                     /old_locus_tag="LB317_13575"
                     /pseudo=""
     CDS             7092..7721
                     /gene="mobV"
                     /locus_tag="LB317_RS13565"
                     /old_locus_tag="LB317_13575"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            7815..8360
                     /locus_tag="LB317_RS13570"
                     /old_locus_tag="LB317_13580"
     CDS             7815..8360
                     /locus_tag="LB317_RS13570"
                     /old_locus_tag="LB317_13580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_031788368.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSDNEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     gene            complement(8402..8686)
                     /locus_tag="LB317_RS13575"
                     /old_locus_tag="LB317_13585"
     CDS             complement(8402..8686)
                     /locus_tag="LB317_RS13575"
                     /old_locus_tag="LB317_13585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001793642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001793642.1"
                     /translation="MKTFIHNKLLYYQCQTIKGVQLFKTLLLCGKNTPFMWQKHSFYVA
                     KTLLLCGKNTPLGIEIPCCSRAEQAPKKVFKKIYKNILKSSRGATYFSS"
                     /name="hypothetical protein"
     gene            8744..9604
                     /locus_tag="LB317_RS13580"
                     /old_locus_tag="LB317_13590"
     CDS             8744..9604
                     /locus_tag="LB317_RS13580"
                     /old_locus_tag="LB317_13590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="WP_031788340.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKERENFLKQL
                     ELNWE"
                     /name="RepB family plasmid replication initiator protein"
     gene            9691..10032
                     /locus_tag="LB317_RS13585"
                     /old_locus_tag="LB317_13595"
     CDS             9691..10032
                     /locus_tag="LB317_RS13585"
                     /old_locus_tag="LB317_13595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(10271..10342)
                     /locus_tag="LB317_RS13590"
                     /old_locus_tag="LB317_13600"
     CDS             complement(10271..10342)
                     /locus_tag="LB317_RS13590"
                     /old_locus_tag="LB317_13600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            10491..10676
                     /locus_tag="LB317_RS13595"
                     /old_locus_tag="LB317_13605"
     CDS             10491..10676
                     /locus_tag="LB317_RS13595"
                     /old_locus_tag="LB317_13605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(10895..11638)
                     /locus_tag="LB317_RS13600"
                     /old_locus_tag="LB317_13610"
     CDS             complement(10895..11638)
                     /locus_tag="LB317_RS13600"
                     /old_locus_tag="LB317_13610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843757.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEAKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     gene            12049..12725
                     /locus_tag="LB317_RS13605"
                     /old_locus_tag="LB317_13615"
                     /pseudo=""
     CDS             12049..12725
                     /locus_tag="LB317_RS13605"
                     /old_locus_tag="LB317_13615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            <12736..13018
                     /locus_tag="LB317_RS13610"
                     /old_locus_tag="LB317_13620"
                     /pseudo=""
     CDS             <12736..13018
                     /locus_tag="LB317_RS13610"
                     /old_locus_tag="LB317_13620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            14227..14844
                     /gene="cadD"
                     /locus_tag="LB317_RS13615"
                     /old_locus_tag="LB317_13625"
     ARG             14228..14841
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            14863..15210
                     /locus_tag="LB317_RS13620"
                     /old_locus_tag="LB317_13630"
     CDS             14863..15210
                     /locus_tag="LB317_RS13620"
                     /old_locus_tag="LB317_13630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            15370..15462
                     /locus_tag="LB317_RS13625"
                     /old_locus_tag="LB317_13635"
     CDS             15370..15462
                     /locus_tag="LB317_RS13625"
                     /old_locus_tag="LB317_13635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            15674..16648
                     /locus_tag="LB317_RS13630"
                     /old_locus_tag="LB317_13640"
     CDS             15674..16648
                     /locus_tag="LB317_RS13630"
                     /old_locus_tag="LB317_13640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_000072390.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKKLKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKNYKATLVDIKGLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     gene            complement(16768..17583)
                     /locus_tag="LB317_RS13635"
                     /old_locus_tag="LB317_13645"
     CDS             complement(16768..17583)
                     /locus_tag="LB317_RS13635"
                     /old_locus_tag="LB317_13645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(17576..19019)
                     /locus_tag="LB317_RS13640"
                     /old_locus_tag="LB317_13650"
                     /pseudo=""
     CDS             complement(17576..19019)
                     /locus_tag="LB317_RS13640"
                     /old_locus_tag="LB317_13650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            complement(18991..19584)
                     /locus_tag="LB317_RS13645"
                     /old_locus_tag="LB317_13655"
     CDS             complement(18991..19584)
                     /locus_tag="LB317_RS13645"
                     /old_locus_tag="LB317_13655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(19848..20228)
                     /gene="blaI"
                     /locus_tag="LB317_RS13650"
                     /old_locus_tag="LB317_13660"
     ARG             complement(19852..20228)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     ARG             1439..2283
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             1..8892
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          13076..13223
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          8745..9604
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.884"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(10896..11638)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          7093..7367
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 cgttcgaagt accaattaac tgaattttgc attgctgtat ttaaatcttg ttccttattc
       61 caagactcga aaagataatg tttatgattc catgacatac gtgaattttt atcacttata
      121 atatgacggt caagtccaaa cagtgctaaa taaattttgt aagttgaatc aggagaatat
      181 ctttttctac tttctttttc attataaata tagtatttgt ctttcttcat gctgtacata
      241 acgaaagatc cactatttga accaaaattt ttactttcat ctaaaatttg gtaatcgctt
      301 tgtaagggat ttttataatt ataatcagtt aaggattgcc ccattaaaaa ctggctttga
      361 attatcatga taaaaaaagt aaaaatacaa ataaaaatta gaattaattt tgactgcttt
      421 ttcagatcgg cttcttttat attaattaat ctatttttga gtaatgattt tttaccatta
      481 aatgaatggc ttaatatatt tttgttgaaa aatgaggttt ttaatacgga gtccataata
      541 gattccgcat aagttttaaa ttcatttttg ttaatattat taaggacaaa tctatcggct
      601 tctacttcat tgtcatgaat tatctttctt tttacaatat gtactaatgg attgtaactc
      661 ataataatag agaagatatt aaagataatt aaatgtaaag tatctctatt tttagcatga
      721 gcatattcat gcagtattat atattttagt cttttatcaa ttacactttt aaaatatgaa
      781 ctaggaatca aaataatata tttcccatac caaaaagtta ttggagattg aatagcctct
      841 gcttttcgaa tcacaatatt ttttttatat tgatggttga aaagtatcgt atctatttta
      901 tttttttcat tttcgtttag ataaagtgac tgtttcttta aatatttaag atataataag
      961 gctttcaaaa atttaaaact taaaataata actaaaacta tccaaataac tgtgcagata
     1021 ttatcaattg aatcccaatt aaacttatgg atatctgttg cgaactcttg aacaggtttg
     1081 gtggtaatta tgttatggtt caagtcgtgt gacttacttt caactgtggg cgcttgatta
     1141 ttcacattat taaattttat aaaagagaat ttaattggga taaaaggaat taatccagca
     1201 agcacagtta gataccaaac tttataattt aaactataat taaaatagcg ttttaatatg
     1261 tacctaaaaa atactaacaa tagaaatata aaacaaaagc ttactacact cattattagt
     1321 aatttagcca ttttgacacc ttctttcaaa tatttataat aaacaattga catcaatatt
     1381 acaattgtaa tattattgtt ttgtaaaaat tacaactgta atatcggagg gtttattttg
     1441 aaaaagttaa tatttttaat tgtaatggct ttagttttaa gtgcatgtaa ttcaaacagt
     1501 tcacatgcca aagagttaaa tgatttagaa aaaaaatata atgctcatat tggtgtttat
     1561 gctttagata ctaaaagtgg taaggaagta aaatttaatt cagataagag atttgcctat
     1621 gcttcgactt caaaagcgat aaatagtgct attttgttag aacaagtacc ttataataag
     1681 ttaaataaaa aagtacatat taacaaagat gatatagttg cttattctcc tattttagaa
     1741 aaatatgtag gaaaagacat cactttaaaa gaacttattg aggcttcaat gacatatagt
     1801 gataatacag caaacaataa aattataaaa gaaatcgggg gaatcaaaaa agttaaacaa
     1861 cgtctaaaag aactaggaga taaagtaaca aatccagtta gatatgagat agaattaaat
     1921 tactattcgc caaagagcaa aaaagatact tcaacgcctg ctgctttcgg caagacttta
     1981 aataaactta tcgcaaatgg aaaattaagc aaaaaaaata aaaatttctt acttgattta
     2041 atgtttaata ataaaaacgg agacacttta attaaagatg gtgttccaaa agactataag
     2101 gttgctgata aaagtggtca agcaataaca tatgcttcta gaaatgatgt tgcttttgtt
     2161 tatcctaagg gccaatctga acctattgtt ttagtcattt ttacgaataa agacaataaa
     2221 agtgataagc caaatgataa gttgataagt gaaaccgcca agagtgtaat gaaggaattt
     2281 taatattcta aatgcataat aaatactgat aacatcttat agtttgtatt atattttcta
     2341 ttatcgttga catgtataat tttgatatca aaacctgatt ttccctttat tattttcgag
     2401 atttattttc ttaattctct ttaacaaact agaaatattg tatatacaaa aaatcataaa
     2461 taatagatga atagtttaat tataggtgtt catcaatcga aaaagcaacg tatcttattt
     2521 aaagtgcgtt gcttttttct catttataag gttaaataat tctcatatat caagcaaagt
     2581 gacataattg ttgaatttat agtaactgaa acgtatgatt agggtgtata ttaattatga
     2641 gatggaaatc aatgattgtt ggctatgcga gagtatcatc gaacgatcaa aatttagaaa
     2701 gacaacttga aaatttaaag acgttttgtg ctgaaaaaat atttacagaa aaacagtctg
     2761 ggaaatctat tgaaaataga ccagtacttc aagaagcact taactttttg aggatgggag
     2821 atcggtttgt agtagaatcc attgattgtt taggtcgtaa ttatgatgaa gtggttggca
     2881 atccattact ggataagttt atgaaagatt taattattca aatattagca atggtttcag
     2941 aacaagagag aaatgaaagt aaacgtcgac aagcgcaagg aattcaagtt gcgaaggaaa
     3001 aaggcgtata taaagggcgc cccttacttt attcaccaaa tgctaaagat ccacagaaac
     3061 gtattattta tcatcgcgtt gtagaaatgt tagaagaagg ccaatcaatt agtaaaattg
     3121 cgaaagaagt aaatataaca aggcagacga tttacagaat taaaaacgat aatgatttga
     3181 tttaataaac tttgtttcaa tgcaactgag agcttctcac agcgtctcaa aacagatgat
     3241 tataatctat tatgagtttt taataataag acaagaaaag agagcgtaaa tatgctctct
     3301 ctttttctca ttaacgaacg tttataacgc aatcatgatg agagtattaa tacagttaat
     3361 tatttgaaat actttagttt atataatgtt gaattatagg tagtgaaatt gtatttatta
     3421 tacattgtca tatcgttgtt taatgatagt taatttaagg ataatagaat taatattata
     3481 tatagatgaa caaaacaagc aacagagcag aaaaaacact tttagattat ttttactcat
     3541 tctctatttt atttattttt gctataataa ataaagaata ttaaatggat gtgtttttat
     3601 gaaaaagaaa tttgtttcta gttgtattgc tagtacaatc ttattcggca ctttattagg
     3661 tgtaacttat aaagctgaag ctgcaacagt acatgtagct ggtggtgttt ggagccatgg
     3721 tattggaaaa cattacgtat ggtcttatta tagtcacaat aaaagaaatc atggttcaac
     3781 agcagtaggg aaatattcat cttttagtgg tgttgctcga cctggtgttc aatctaaggc
     3841 atctgctcca aaggcttggg gtggaaacaa aacattttat agtcttcact aattacatat
     3901 attaattaag gagaatagac agaattaagt aaacttaatt ctgtctattc tcttgaaaga
     3961 ggcaatatga aaaaattcaa attattttta gattttagta ctttattatt aatttcaggg
     4021 ctattatttt tatttttctt caaagaaaat gaagaaatta tacctgaaag ttccaatatt
     4081 ttaacaatct ctaattggga taaatctaac agtaaatcaa aagtgttaga tgtcattgaa
     4141 tcaggcgcca aaaatcaaaa tatacaaata attaaatccg ttaaagattt tgataataaa
     4201 aaagaatttt ttgttttcaa ctcaaaacga aataattctg actttatacg taataaaaca
     4261 tcacttttaa ctccatcaga tttattaaac agagagataa aaggaaagta ttatattatt
     4321 ggtgaacatt tcaatgtaga agagcttacg agtgaattaa aaaaagctgg tttaacatct
     4381 gaagttgaat acataaatag aaacatatta ttttttgaat tagtcataga taatgattta
     4441 ttagtgcctt tcatattctt aggcgtatta tatcttttgt acttcttata tgacagagga
     4501 tataatttga aattttatgc tattcaaaag ctacatggct tttcaactac acgcattatt
     4561 tttcataata ttcatataaa aatcatttat tggctagtac ttaccgctat tttctttatt
     4621 gctaatatat taatcattca tatagccaat ttagaattgg atttcttaat gtttattcgt
     4681 agatttatcg tgttgctttt tgtttttgct tgtattacta cattgctgtg gctgatttcg
     4741 tatagtcttc ttttgaagtt aagtattcca ttaatcttaa aagggaaaaa aggatataag
     4801 ttttcaatat ttatgggtac cttcaccaaa tgtatcatgg tgctaatact atctttttta
     4861 ctggcacaaa atttaaatgc ttatacgaag ttaaagaata tatatgactc tgaaaaaatc
     4921 tggcaaaagt tagataatta ctatacatta gagatttctc ctaatattag aaattcagaa
     4981 gaaaaacaaa ttttagaaac taatatatac aatttaatta agaaaagcga acaacttggt
     5041 ggattgcttt taaagaataa taatatagcc aatcccgata aaaacaatta cattcctgaa
     5101 aatggcaatg tcttttttat caataacaat tttctgaatt tctataaaaa tataaatcat
     5161 gattttaaaa tgattgacaa tcattcggat aaaataaacg tgtttattcc tccaaggtta
     5221 caatatcaaa aatctgaaat tcaaaaaaat caccaaggat ggattgactt tcaaaagcaa
     5281 caaaacaaaa aagtagatgt gcaagtactg tcaaaaaacg tatctgtttt ttcttttgat
     5341 cgcacaacta atttgaaatt tgggtatcta gattctccaa tagtaatgtt gttgacactt
     5401 gacgatttaa caggagattt ttatttagct gctgtttctc aaggtggata tctatttaaa
     5461 gatttagata cacttaaaca gttgcttaaa gataatcacc tagaagaaga aattagcggt
     5521 ataactaatt acaaggattc tgtgttaaat gaattaaatg aaacgaaaac aaaaatgata
     5581 ataacaatag ttactattat tattaacgtt ttcattcttt tgatagctac tgtatttgaa
     5641 acaattcaat attttagctg gaataaaaag caactattat taagaaaaat tcatggttat
     5701 tcattattca gcagtaatgt acgttattta acaatttcta tcttactttc tattatgtta
     5761 gcttacacta cgcatatttt atttggttca aagatattac tattcataat aatgtctatt
     5821 gctattattc aacatttact tcaaattgct tatattaaat atcttgaaaa atactttaaa
     5881 gatttaatga gggagattta aacaatgaaa agaactttaa ttattgtaac aattgtacta
     5941 ttaatcatca tacttagtct gttattggtt agaaatgagc atttagatcg ttttaaccca
     6001 ctgttaaaag aaaaagtatc ttatgccaaa gttccaaaag atacccagga ctatagaaat
     6061 ataactgtat actctaaaaa tggagaaaaa aagagttata aattggattt tttaggttat
     6121 gatcctacaa aagaatatgt gaaagtaaat cataaaggga aatatgtgcg ttcgatagaa
     6181 tacattacaa aagatattcc tagcttttta aaatgaggtg accgatagtg ataaaacttg
     6241 aaaatgtttt tgtaaaaaaa ggtaataaaa acattttaga cggatgtaac tttaattttg
     6301 aaaaaggaaa atcatatgct ttagttggag aaagtggcgc tggaaaatct actttactta
     6361 acataatcgc tgggttcgaa gatgtatcac aaggaagcat atatattgaa gataagttac
     6421 taaaaaagaa agtcgatttt tatagatata cgttagggta tttgtttcaa aattttgctt
     6481 tacttgaaaa tcaaacaatc agtcaaaatt tagatttagc cctaaagttc aaaaagaata
     6541 aaaaagataa tatgaactta aagaaagaag tattaaaaaa ggtcggccta gatttagata
     6601 tcaagagaat tgttagttct ctaagcggtg gtgaacaaca aagagtagca ttggcaagat
     6661 taatattaaa agatccgaaa atcattttag ctgatgaacc tactgggtca ctagatacga
     6721 aaaatggaaa aatagttatt gatttattat tgaagctact tgatgaaaat aaaactatga
     6781 ttgtcgtaac gcatgattta gagcttgcga aacgatttga tgtcatagtc aatatttctg
     6841 agcttagaag ttaagaaata ttgataggta tagccataca tagagaaaaa acaatatgaa
     6901 atatgattag tcattacttt tgagtttttt aatttaagga ctggattttc cagtcctttt
     6961 ttatgatgac aaaaaacaag cctcgcagag cacacgtttt taatgactta tttggttttt
     7021 aataagtcta gtatgttaaa acttttctgt gtttaggtgt tataatcata tgcagtggaa
     7081 gttgatttat tatgtcttat tcaattattc gagttgttaa agtgaaatca aaaacaaata
     7141 caagaggtat tcaaagacat attcaaagag aaaataaaaa ttatgaaaat atagatattg
     7201 atttaagtaa gtcatattta aactatgatt tagtcaatga tactaagttt gattttaata
     7261 aaaaaattga tgagaaaatc gaaaaaaatt ataaagggaa acgcaaaatt agaacagatg
     7321 ccattaaaca tattgatgga ttaattacat cagataatgt gttttttaat caattatctg
     7381 aagaagagac aaaatagttt tttaagcatg ctaaagcgtt cttggaagaa gaatacggta
     7441 aagaaaatct tttatatgcg acagtacata tggatgagat aacaccacat atgcattatg
     7501 gcgtagttcc tattactaaa gatggacgtt taagtgcgaa agaagttgta ggtaataaaa
     7561 aagcattaac cgaattccaa gatagattca atacgtatat taataagcaa ggctatgatt
     7621 taaaacgagg aatttctaga caacttacaa aagaaaaaca tgatcaagtt agccgttata
     7681 aacaaaaaac agaatatcat aaacaaatgc atatgcgcta gaagcaaata gaggattatt
     7741 taaagcaaga aaatgataaa ttgatacaaa actaccaaaa atcattagat acgcttaaaa
     7801 agcttctgag tgtcatgtat gaaattaaaa ctaaaaatgt aggtggatgg tttcataaag
     7861 agaagcaaga aacaggcaat attgtaatta ctaaaactga ttttgaaaaa tacactaaac
     7921 aaattaaagc agcacagatg atattagatg attatgaatg tattaaaagt gggaagtcat
     7981 taaaaaaagc agagaaacaa aatgaaagtt tagttaatga attgactagt gtccatatgg
     8041 aaaatgaaaa gctggttgaa gaatttaatg atttagcaca acgttataat tatttgttgt
     8101 cagataatga aaagaaagat aaagaactaa attatacgct taagttattc aatcaagttt
     8161 ttaaaatcat taaaagtatg atgaaagaag agcgttatca tacactaata aatcatattg
     8221 ataatcattt agacaattct aaaatacgtg aagtaatgac gatagataac aatgatgaac
     8281 agttctttaa gaagaaatat caagcacaag aacgagaaat catttttaaa gaagatagag
     8341 aagatggtta tacattataa aaatagatat ttaaatgcat ttgtttgagg ttaattattt
     8401 tttaggatga aaaataggta gcccccctcg aactttttaa tatattttta taaatctttt
     8461 taaaaacctt tttaggggct tgttcagccc tagagcaaca agggatttca atgcctaaag
     8521 gagtgttttt gccacataaa aggagtgttt ttgccacata aaaggagtgt ttttgccaca
     8581 taaaaggagt gtttttgcca cataaaagga gtgttttaaa aagttgtact ccttttatgg
     8641 tttgacattg ataataaagt agtttattgt gaataaaagt tttcaaatgg gagtgtatat
     8701 tcaaacgata ctcctttagg ttcgtaataa agggggctgt atcatgacag gagagacagt
     8761 tgtatataaa aatgaaatga atttagttcc attaaggcga tttacagcta ctgaaattaa
     8821 tttatttttt gcgatgtgta ataaattaaa agagcaagat actaatacat tacgtttgtc
     8881 ttttgatgaa ttaaaaaaat taagtaatta tagtccagaa acacgtaata ttaatagatt
     8941 tgctaatgat ttagataatg tgtataaaaa gatgttgaat ttaaccatta gatatgaaga
     9001 tgatgatgta atagaaagat tcgttttatt caatcattat agaatccata agcgagaaca
     9061 atatctagaa atatcaactt cttcaaattt aaaacacata ttgaattcaa ttactaataa
     9121 ttttacaaaa tttgaattaa aagaaatgac taggcttaaa tctacatatt ctaaaaatat
     9181 gtttagatta cttaaacaat acaaacatac aggctattta aaaattcaca tcgatgattt
     9241 taaaaatcgt ttagatatac ctaaatctta tcgtatgact gatattaaca aaaatgtttt
     9301 taaacctatt attattgaat taggttctat atttaataat cttactatca ataaaatcaa
     9361 agcgaaaaaa gggcgtaaaa ttgaatggat agagttcaca tttgacgctg agaaacgcat
     9421 tcataacaaa cgacaacctc aaatgtccaa gatagataaa tcaagacaat atgtgaggcg
     9481 tgaaaagacg cctaaatggt tagaagaacg gtcatatgaa aagcaacctc aaaaagatta
     9541 cgacccacaa ttagagaaag aacgagagaa ttttttaaaa caacttgaac tgaattggga
     9601 ataacgcaac ttttcgttgc gagttggtta actaaaagta tcgtgacttt tcaattattt
     9661 taattatagt ttgagttaag gagtgatttt atgaaattag ctgaagctat aaaagaacag
     9721 agagaattaa aaggatggtc tcaagaggaa ttagccaata tattaaaggt ttccagacaa
     9781 agtgtttcta aatgggaaag tgccaaaaac tatccttcct tagatatttt gattgctatg
     9841 agcgatttat tcggaatctc tttagagcat ttaattaaag gagatgcacg ttttaaaaaa
     9901 gttattttag agggaaatta tagagagagt aacagggtac cttccatagt tgattttctt
     9961 tatgattttt ggtggctttt ctttcctgtt gccggatttt tagtttgggc cattcattcg
    10021 ttcatgggtt gattttaaaa tcaaaattta atgcacatca ggcaatatga aaaaggaaag
    10081 tatttttacg acaccttgaa atgtattgat aagaatagaa gagtttacaa aaggcaatat
    10141 gaaatatata ctaaaagtaa caagaatttc gtttgtaaac gcaccaaacc ccgaactatt
    10201 cgccgtagtt cggggttttt tggtgaattg gctttaatcg tctatattat tttttatcac
    10261 gtttatggag ctaataacca aataacgtaa cgagacaacc actgattgcc gttgtcatga
    10321 tgtgaacaag aatttcattc ataaatcgca cctcctctct acgccgaatt gacatctgag
    10381 agatagacga ccttcacatt ataacaaatc tctccttcca tgaaataaca tgaatattaa
    10441 taaatgttgt tatatattaa agataaataa atataagggt gggattgata atgtttggcg
    10501 atcaaagaca agaagctaca aaatatgtca ttaaagaagg ttatcaagat atttatttcc
    10561 tcaacaaaaa cggggaatgg tattatttcg aagtaagaag tgtctggcgt ggcaaacata
    10621 ttattagagt taaagatggt ttgttaggtt ggagaaaaga aatagtaact gaataaagat
    10681 acaaaatact tgccaatgca aaagaatgaa aacgcgtcaa atcaacgatg tataaaagat
    10741 gcataaaaga taatgaaagt aaaaagccat aaatgccgtc atataggcat ttatggcttt
    10801 ttgtttggtt aatataatcg atgattatca gaagttcaat tcacataaaa aagcacggct
    10861 aatttatgaa cttgtcgtac ctttttaatt aaaattagtt accaaataga cgactccaaa
    10921 accccttttt agcttccgtt tcttcactct tttcttctat atcactatca ttgtcatttg
    10981 gattagctga aacgtcttct ctttgtgctt cttcaccttg tgtactttcg tcgctttgac
    11041 ttccagatat atccttatat tgaatctctg tttctttagt ttcttcctga tctcggttaa
    11101 tatttacagg actagtagta tatgtttttt cttgtgcatc aacgttttgt ctagcgttag
    11161 tagatgtatc aaagggataa ttaaggtgtt tttctttttc taattgattt tctaattttt
    11221 gaatcttttt attactctct aatgccagaa cttgctgatt ctcaagcaat tttgatcttt
    11281 cttgcaactc ttttctgtaa aattcaattg ttgtttcatg acgactttct tgtttttcaa
    11341 tttgattatt taaagtatta atctgatttt taagtatttc tactatttga gcatcgcttt
    11401 tagattcaaa attaatatta tccgactctt ttttttgttt gtcttcagta gcactttcaa
    11461 aaccatattt ctttttattt tcatttactc tttgaatgat tttttctata tcggtatctt
    11521 ctttaataaa cgaagtgttt tcctgtttta ttgtctctat attcaatctc ttaatattat
    11581 taaaaatcgt ttgcttacta acccctaatt cttcactcaa cctttttaca cttttcatat
    11641 catcaaccct ttataaaatg tttataaacc cttagtaaaa tattataagc ttataacgat
    11701 taataataaa gtaatcgaca aataaaaata taaattcgcc aaccttttta tcaagggttt
    11761 gtaaagggtt tatggtgttt atcaaaggtt tataaaccta tattttccct tttttaagtt
    11821 tattcaaagt gctataataa ccttaatata acaaaaaccc caactactgg taatagtcgg
    11881 ggtttggtaa taaaacgttt agaaactgtt tatttatata attttcgata cttagattat
    11941 ataatgaata atatcttagt gcaagcacct agattattaa ataaacacaa aaaatgtaag
    12001 cgttttatta cctcttacca aactaaaatt cggaaagagg tttttattat gtcaattaaa
    12061 ctttacaaca taaatgagga atacagagaa aagttttatc aaataccgaa agtatttttt
    12121 acaaatccta aatatatcaa gttatccaat gatgcaaaaa tggcatgggg tattcttaga
    12181 gatcgtttag atttatcaat taaaaatggt tgggttgatt ctaaaacagg taatatttat
    12241 ttttattaca aaaatgaaaa cccacaaaat atattaaatt gtaaaaaaga taaagtaatt
    12301 aaaataaaga aagaacttaa ttgaagccga attactacta caagaaagac aaggtttaaa
    12361 taagacaaat aaactttatt tagttaaacc agaagtaaca gaagatgata tttataaaat
    12421 tcaaaagcaa gaaaacactg ttgagagcag caatggcaag gaagtcggaa aaaccgactt
    12481 caagaagtcg ataaaacaga atctaatgat actgaactta gctatactga atctaacaat
    12541 actgaaataa atgatatgaa tgacttgaat gatatagagt ccgaaaatga aattagtaat
    12601 cattcaagtc aatgcaaggt tatttaatgc aaacaatttt aactgaattt gaagaaacac
    12661 atgcacttta tatgcgccgt aaaaacatga aacaatataa tatctttaat caatcattca
    12721 aatgatttta taacaatcaa agatacatca aaatatttcg ttaaatcatc tgacttttta
    12781 actgatagcg atgaaaaaat caagaaattg tcagtgatct agaaaaagat ttgtatcgaa
    12841 aacgtatgtt aagttatggt ggattgctta aataaaaaca taaaatttta aacttagacg
    12901 atgctgaaga tggcaattta attaatacaa gtgatgaaga taaaatagca aatgaagaag
    12961 aaaaggcaca ttcgattacg gcaattttga aaagcaaaat tattatttaa ggcattagtg
    13021 ataactgatg tcttttttta ttactttttt gtaaaaaaag tgctgtctta tttttgtgac
    13081 aaatgctgta tgtagtgtca caaaagtgtg acacttgagc tttttatgac cccacacaaa
    13141 aacattttcg aagccttgaa atatctggct ttgccagatc ccccattcat tgatggggac
    13201 aaatttccct tatgctctta cggagatttt agagttaaat taaaatttct aagtttttga
    13261 taagaaaagc cctgcaggaa tttagaagaa cgtggggaag ttttaaagaa ttttatgcta
    13321 atttttaatt tgcatgtaaa tgggcagtgt ctaaaaaata gttattgttt ttgctcaaat
    13381 ttttgttttt gaaaatagca tatatttatt tggctcatat ttgcgtttta aaagcgtata
    13441 taagttttag ataaaactat atgaatcacc cctaaatctt taaaatgccc tcttaaaatt
    13501 caaaataagg gcataaaaaa taaaagcccc cccagataaa gtgaggtagc tttttctttc
    13561 gacgccgtat cgtcgatgta attcaaaaaa gttatgggct ataaatctac atcacttttt
    13621 caagaatgta gtagcaatat tcaacgcaaa ttaattttta taactgctcg gaatatctca
    13681 agccgtttct ttaattttga aataaaaaaa tcgacgaagg tcgattacgt ttttgcacat
    13741 gtcgatttat ccgacgtata agtgcgccct tacgggattt aactagatta taacgacgaa
    13801 ttttagacct gtaaagcaat aacaattagg tctaccaggt agataaagtg tacaaagtag
    13861 aaccgaaaaa gttatttatt ttgaagattt ttcgtagata taatttgcta ataaacttcc
    13921 taaaactgaa taaagaaaaa tagttaaact catgtaatca ctccataatt ctgaagtgtc
    13981 tccatgtcta cgcatagaca cgcatttatg ccgagaaaat ttattgtgcg ttgagaagaa
    14041 cccttaacta aacttgcaga cgaatgtcgg catagcgtga gctattaagc cgaccattcg
    14101 acaagttttg ggattgttaa gggttccgag gctcaacgtc aataaagcaa ttggaataaa
    14161 gcacctatga ttatttaaaa atataagtta taatacattc aaaaatattt ttgaatgagg
    14221 tgtattatga ttcaaacggt tgttgctgct gctgttcttt atattgctac agcagttgat
    14281 ttattagtaa ttttattaat attttttgct agagcaaaga ctagaaaaga atatagaaat
    14341 atttatgttg gtcaatattt agggtctatt attttaatat tagttagttt gtttttagct
    14401 tttgtattaa attatgttcc agaaaagtgg atattaggtt tattgggttt aataccaatt
    14461 tatcttggaa ttaaagtggc tatttatgat gattgtgaag gagaaaagag agctaaaaaa
    14521 gaattgaatg aaaaaggatt gtctaaatta gttggtacgg ttgcaattgt tacgatagca
    14581 agttgtggcg ccgataatat tggtttattt gttccttatt ttgtgacatt aagtgttact
    14641 aatttattac ttactctgtt tgtcttttta attttaattt tcttcttggt gtttactgca
    14701 caaaaattag ctaatatccc aggaattgga gaaattgttg agaaatttag tcgttggatt
    14761 atggctatca tttatatagc tttaggttta tttattatta ttgaaaatga cactattcaa
    14821 acaattttag gatttatatt ttaatttagg gtgtgatttt atatgagtta tgaaaatact
    14881 tgtgatgtga tctgtgtaca tgaggataaa gttaacaatg ctttaagttt tttagaagat
    14941 gataaatcta agaaattact taacatttta gaaaaaattt gtgatgagaa gaaattgaaa
    15001 atcatattat ctttgattaa agaagatgag ttgtgtgttt gtgatatttc tttgatattg
    15061 aaaatgagtg ttgcttcaac ttcacatcat ttaaggcttt tatataaaaa tgaggtactt
    15121 gatttttata aagatggaaa gatggcatat tattttatta aagacgatga aataagagag
    15181 tttttctcta aaaatcagga gggtttttga aacgagtttc ttcttgtctt gatactataa
    15241 aaaacaaagt tatataacat aagacgactt atcggaagtt atctatcatc gtatattcgg
    15301 agatgatata atatacaggt cgcctatctc tcaggcgtca attcagacgc agagaggagg
    15361 tgcattactt tgctaatcat tttcgttcac atcatagcac cagtcatcag tggctgtgct
    15421 gttgcgtatt atacttattg gcttagtaaa cgcaacaaat aattaatagg cgactttata
    15481 agccagcatc gaaaaaatcc ccacactatt gcagtagtgt ggggattggt gcattaattg
    15541 ttaatcattt tcgttatcta gattataaca ctggttagta gaggaatgca aaaagataat
    15601 attttaagta gtctttttgg atattatcat atgatatatt tatgtaaatt gattttttat
    15661 taaaggagca tatatgagta atactaaaat taaatatcaa atttttattt catcaactta
    15721 tttagattta atagaagagc gtcaagcagt agtagaagca gttttaaaca gtaataatat
    15781 tccagcaggt atggaacttt ttaactcaag tagtaaaagc caatgggaaa taataacaca
    15841 atggatcaat gaatcagatg cagtgatatt attgttaggt tctagttatg gaacaattga
    15901 tagtgaagaa aatattagct atacagaaat ggagtacaat tttgctaaat ctttaggtaa
    15961 acctatatat gtttttgaga tgaataaagc atctaccgaa tccgcggaaa agtctaaaaa
    16021 attagatgag tttaagacaa aagttaaaga aaatagacta attagtccaa atattaatga
    16081 tatttcggaa ttaaaaagta aagtatctca gactttaatg caaagtgtac ctagtgaaat
    16141 taaagaaaat agtggatgga taagagtaca ggattgtggt aaaaatgtaa aaaaattaaa
    16201 aaaattggat gctatacaaa gagatttaga tacatatgat tttttgaaag aagaacttta
    16261 taaaatattc atgtatgtaa aaacttttta tttccagcac acaccatttg atgatagtta
    16321 tattgaagat atagaaaact acctgctaaa ttatgaaaat aatccacata aatcattcat
    16381 gaaaataaaa gtttatgatt ataaaaactt tttaaaacat ttaaaaaaca tattgatttt
    16441 aattaaacaa ggaaaaaagc cattagctca agccggtcat tttaaattaa gcttttacga
    16501 agaggattta aaattgttac aaaaaaatta taaggctacg ctagtcgata ttaaaggatt
    16561 gaataaacat ttttataagg aatgtgatag gtgcttaaaa gcatataata tttttattga
    16621 gggtataaat aaacatttat atgaatgata taagtacacc ctaatcatac atatataatt
    16681 gttgtcactt tactcgatat atgagaatga ctttacctaa taaatgagaa aagcaacgca
    16741 ctatattaaa atgcgttgct ttttctatta tcgaatacct ataactaaac tatctctagc
    16801 tgtttctaca acttctgtac ttattttatc taaaccattt atatccataa ttctgtctat
    16861 ctgcgcaaat aaacgatgaa tcagcctaaa attccctttt gtaattttaa taatcgtcgt
    16921 tattgcctca taatcagtaa agtcttcgag ttttaaatca aatcctaagt cttgccactt
    16981 atattctaat atatgatgcg tctcatcttt acttagatta tcaaattcat gcgcaaaacc
    17041 tatacgcgaa tatagttgag gataacgaga tagttttttc tctatacccg gcataccaat
    17101 aaatatcatt gctaaattat gttcatcata aatagctctt aattgctcta aatgttgcac
    17161 tttaaggcga tcaatctcat ctactataat taaatcaata tatttaaaca tatcactata
    17221 atgtttacta tgttcatgtc catacttatt tacaacatgt aatttttgac ccaaatcaat
    17281 gattgcagta atactatata aatcattcct taatttagtt tgtttttctg ctggtgcatt
    17341 ataaaatatt ttatccaccg atagtatgtc atcggtcgtt ttactagcta aatcttccca
    17401 acctctatgg ttaacttgtt tttcaatagt atcccaattt gtgtaatacc tagacgataa
    17461 agtttttccg acaccaggtt gaccataaca tataccaata tactgatatt taatacaagc
    17521 atcacaaaat tcagcaaagc gtttatactc tttcgtttca atgaaatttt gatttttagt
    17581 cattacgata tctctttaat tttttgacgt ttttagtcgt ttcttgaggt gaataaccac
    17641 aatttttttc ttccttaatt aattccgtgg tacttggact agcaatattt tgttttaagt
    17701 gttttcttct ctgactacga gcgtgctgta tgtcttttat atctatggag taatcagcta
    17761 tttctggaca tatagcagta caaagaaatt catctctata aaacacacgt atttcagcca
    17821 tatcatttgg gttataacga atcagtacat attcacctac ataagcttct agattagtat
    17881 tactgtatcg aaaaccttga aaatgaatgc catctgaatg aacttttcta gatttaggta
    17941 tttccaacaa taataaatca agttgttcta agctacttgg catattaggg aaaaagtgat
    18001 tactattcca atgactgata ggcgtggtat gaatagtact atgttctttt tgattataat
    18061 cttcaattaa aaagtaacgt aatttttctt caaaattgtg aaaatttatt agattactag
    18121 gagtatcatt attgtttata tatccaggca gttgttctaa gaaagtttga ttaactgtct
    18181 gaaagaatcg ttctattttt ccacgaccac gaggaacacc aactttcgaa aacatcaagt
    18241 taattttcaa atcaatagcg acttgttcca tatgatgtga agtaaagtca cttccatgat
    18301 ctgtgtagaa tttttcgggt ataccacaca ctggccaatt ggtatcattt ttattccata
    18361 ttgcttggtg tagtgttaat gctgtgtttt gagcattggg gggcatcaaa acttaagaaa
    18421 tagcctgcaa ttgcacgact atagtcatcc ataataatag ttagccatgg tctattgata
    18481 ttaccttttt ggtctaatat aaagatatct agcaaagtat ggtctgcttg ccatatttca
    18541 ttgggtctcg aggattctct aatttgtatt aaatcgtact tattttgata gtatttttca
    18601 ccctgatgag agaaatcaat aacagactta ggcatcgctt taataacact ataaatttgt
    18661 ttataacttg gtatatcaaa attattttct ttacagtaat tagtgatttt cctatgaatt
    18721 gtggctatac tatttctttt attcataagc gcaaggcgtt caatttcatc aattatcttt
    18781 ggttctattt tacgtgttcc tttatcagct cttgtcgcat agattagtcc tttaagtcct
    18841 tgttctttat atgacttatt ccacctataa agggtgctta acgcaatccc tttactttta
    18901 gaaatacttg ataaagattg ttcgcctagg ataaaaggtt ttataatatt gtacttttga
    18961 gtagcttttt tacgtttggc ttcagaaaaa ttagttagat acttctcctt gtttttcatc
    19021 ttccttgtcc tccaatttat tgaggtaacg ataaattgtt gtacgtgaaa catgccactg
    19081 ttctgcaatt gtcttaattg gcgtgccatt atcataaagg gtcttaagta agtttaaatc
    19141 tttttgattt aatttttctg gtctgcctcc atatcggcct ctagcacgtg ctgcaattcg
    19201 gccagctgaa gaacgctcta aaattaaatt acgttcaaat tctgcaaatg ctgcgaataa
    19261 atgaaataat aattgtccag ttgaacttga tttatccatt gttatatttt cttctaaact
    19321 atggaaactt acacctcgtt cgttaagctc attaactaat gtgattaaat cctccatatt
    19381 acgtcccaat ctatctaatc tccaaacaac aatcgtatct cctgacctcg caaattcaat
    19441 tgctttatct aaaccaggtc ttttactttt tgaaccactc atatggtcat taaatatctt
    19501 ttcacaacca tatgtattta atcgatcctc ctgtaaattt aaattttgta atccagttga
    19561 aactcttgca taacctattt tcaaaataca aacctcctat atacatcttc agtgtaccat
    19621 aacttaatta caaggtcttt tatgaacata gattttttgt tgggtttttg aacacataat
    19681 cctatgtaat tcttacttat ttagacataa aagaagagtg tacagaaaat ggttattttc
    19741 tgtacactct catctttaat aatatatttt aaatgtcatt aacaaaacta atttaataag
    19801 agtcaagcat agtttacata tgtattatgt ttgaaacata cctctaatta ctttttacta
    19861 atatcattta aaatatctcg caattcttca atttctttgt tatttaattc ttcatttttc
    19921 gcaaaattca acactaaact tttcatatcc cctccataca gtttattaag aaaggtttta
    19981 gcagttttca ttttaatatc gtcttcttta atatttgatg agtaaaaata aatattttct
    20041 gatttgtatc gttttataat ctctttttta tatagtcttg tgattaatgt tctaatcgtt
    20101 ttatcactaa cttctttata tttttgaatt tcaactacaa tttcattagc tgatactgat
    20161 tttttatccc atattatatt cataacatcc cattcagcca tagatatttc aacttgctta
    20221 ttggccattt aaaacaccca ttccttttaa tattttttca cttattaatt cagcattttt
    20281 cccagacggg tttccatctg ataaatgtgt agcaaaataa tacttatcat gatttgtaat
    20341 tacgtaacct acaaaccacc cattattata cttcccgttt actatacctg tacctgtttt
    20401 cccatacagt tcatactttt catttttctt aatcaataat gaagaagata attgattctt
    20461 tgctttttta ctaaaatggt tattttgttc catcatattt ttaaaaacta ttacttgttc
    20521 aagattagat attttcaaac tatcttccat ccaatagctt ttataacttc ccaaattttc
    20581 attaccataa tttaattgct tgagttgagc cgcagtatag ttctttggta tttgattact
    20641 aata
//
